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Shiraishi Yutaro  白石 勇太郎

ORCIDConnect your ORCID iD *help
Researcher Number 10894412
Other IDs
Affiliation (Current) 2025: 大阪大学, 大学院薬学研究科, 特任講師(常勤)
Affiliation (based on the past Project Information) *help 2022 – 2024: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 43020:Structural biochemistry-related
Keywords
Principal Investigator
パパイン様プロテアーゼ / COVID19 / 溶液NMR / 核磁気共鳴分光法 / Gタンパク質共役型受容体 / アレスチン / 核磁気共鳴法
  • Research Projects

    (2 results)
  • Research Products

    (10 results)
  •  Structural basis underlying the substrate selectivity of papain-like protease from SARS-CoV-2Principal Investigator

    • Principal Investigator
      白石 勇太郎
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Institute of Physical and Chemical Research
  •  Elucidation of the mechanism of arrestin activation by G protein-coupled receptors using nuclear magnetic resonancePrincipal Investigator

    • Principal Investigator
      Shiraishi Yutaro
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Institute of Physical and Chemical Research

All 2023 2022

All Journal Article Presentation

  • [Journal Article] NMR Characterization of the Papain-like Protease from SARS-CoV-2 Identifies the Conformational Heterogeneity in Its Inhibitor-Binding Site2023

    • Author(s)
      Shiraishi Yutaro、Shimada Ichio
    • Journal Title

      Journal of the American Chemical Society

      Volume: 145 Issue: 30 Pages: 16669-16677

    • DOI

      10.1021/jacs.3c04115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K15052
  • [Journal Article] Function-Related Conformational Dynamics of GPCRs Revealed by Solution NMR2022

    • Author(s)
      UEDA Takumi、KOFUKU Yutaka、TAKEUCHI Koh、IMAI Shunsuke、SHIRAISHI Yutaro、SHIMADA Ichio
    • Journal Title

      Nihon Kessho Gakkaishi

      Volume: 64 Issue: 4 Pages: 279-284

    • DOI

      10.5940/jcrsj.64.279

    • ISSN
      0369-4585, 1884-5576
    • Year and Date
      2022-12-15
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-22K15052, KAKENHI-PUBLICLY-21H05509, KAKENHI-PROJECT-20H03375, KAKENHI-PROJECT-21H02619
  • [Presentation] SARS-CoV-2由来パパイン様プロテアーゼの阻害剤結合ポケットが示す構造柔軟性2023

    • Author(s)
      白石勇太郎,嶋田一夫
    • Organizer
      第62回NMR討論会
    • Data Source
      KAKENHI-PROJECT-22K15052
  • [Presentation] 交換モンテカルロ法を利用した、タンパク質の動的構造平衡と機能の解明2023

    • Author(s)
      上田卓見,今井駿輔,横溝智貴,猪野麻巳子,白石勇太郎,幸福裕,竹内恒,嶋田一夫
    • Organizer
      第62回NMR討論会
    • Data Source
      KAKENHI-PROJECT-22K15052
  • [Presentation] マイクロ RNA 前駆体 pre-miR-21 の構造平衡が成熟阻害剤の活性へ及ぼす影響の NMR 解析2023

    • Author(s)
      西村優平,徳永裕二,幸福裕,白石勇太郎,今井駿輔,嶋田一夫,竹内恒
    • Organizer
      第62回NMR討論会
    • Data Source
      KAKENHI-PROJECT-22K15052
  • [Presentation] GPCRとの相互作用によるβ-アレスチン1の2段階活性2022

    • Author(s)
      白石 勇太郎, 幸福 裕, 上田 卓見, Pandey Shubhi, Dwivedi-Agnihotri Hemlata, Shukla K. Arun, 嶋田 一夫
    • Organizer
      第61回NMR討論会
    • Data Source
      KAKENHI-PROJECT-22K15052
  • [Presentation] Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR2022

    • Author(s)
      Shiraishi Yutaro, Kofuku Yutaka, Ueda Takumi, Pandey Shubhi, Dwivedi-Agnihotri Hemlata, Shukla Kumar Arun, Shimada Ichio
    • Organizer
      29th International Conference on Magnetic Resonance in Biological Systems
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15052
  • [Presentation] Gタンパク質共役型受容体b2ARのリガンド依存的活性化機構2022

    • Author(s)
      今井 駿輔, 横溝 智貴, 幸福 裕, 白石 勇太郎, 上田 卓見, 嶋田 一夫
    • Organizer
      第61回NMR討論会
    • Data Source
      KAKENHI-PROJECT-22K15052
  • [Presentation] アデノシンA2A受容体とリガンドの滞在時間を規定する構造基盤の解明2022

    • Author(s)
      上田 卓見, 土田 知輝, 栗田 政稔, 水村 拓也, 今井 駿輔, 白石 勇太郎, 幸福 裕, 竹内 恒, 嶋田 一夫
    • Organizer
      第61回NMR討論会
    • Data Source
      KAKENHI-PROJECT-22K15052
  • [Presentation] Structural equilibrium underlying ligand-dependent activation of b2-adrenoreceptor2022

    • Author(s)
      Imai Shunsuke, Yokomizo Tomoki, Kofuku Yutaka, Shiraishi Yutaro, Ueda Takumi, Shimada Ichio
    • Organizer
      29th International Conference on Magnetic Resonance in Biological Systems
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15052

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