KAKU Natsuko 加来奈津子

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Kaku Natsuko 加来奈津子

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Researcher Number	10899355
Other IDs	https://orcid.org/0000-0002-1352-3666
Affiliation (Current)	2025: 大阪公立大学, 大学院医学研究科, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 大阪公立大学, 大学院医学研究科, 講師 2022: 大阪公立大学, 大学院医学研究科, 特任講師 2021: 大阪市立大学, 大学院医学研究科, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 55060:Emergency medicine-related
Keywords	Principal Investigator エムポックス(Mpox) / ペプチドアレイ / ペプチドマイクロアレイ / 受容体結合ドメイン（RBD） / 新型コロナウイルス感染症（COVID-19） / mRNAワクチン / ペプチドマッピング / 結合親和性 / 中和抗体 / RBD / エピトープ / COVID-19 / SARS-CoV-2

潜在的感染拡大を明らかにするハイリスク集団におけるMpox血清疫学Principal Investigator
- Principal Investigator
  
  加来奈津子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Osaka Metropolitan University
Identification of Epitopes Targeted by Neutralizing Antibodies Against SARS-CoV-2Principal Investigator
- Principal Investigator
  
  Kaku Natsuko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka Metropolitan University
  Osaka City University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Factors impacting antibody kinetics, including fever and vaccination intervals, in SARS-CoV-2-na?ve adults receiving the first four mRNA COVID-19 vaccine doses2024
- Author(s)
  Matsuura Tomoka、Fukushima Wakaba、Nakagama Yu、Kido Yasutoshi、Kase Tetsuo、Kondo Kyoko、Kaku Natsuko、Matsumoto Kazuhiro、Suita Asae、Mukai Emiko、Nitahara Yuko、Konishi Ayako、Kasamatsu Ayane、Nakagama Sachie、Nakagami-Yamaguchi Etsuko、Ohfuji Satoko、Kaneko Yukihiro、Kaneko Akira、Kakeya Hiroshi、Hirota Yoshio
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 7217-7217
- DOI
  10.1038/s41598-024-57931-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KJ2622, KAKENHI-PROJECT-22KK0279, KAKENHI-PROJECT-21K09078, KAKENHI-PROJECT-22K15927, KAKENHI-PROJECT-23K24592
[Journal Article] Age-adjusted impact of prior COVID-19 on SARS-CoV-2 mRNA vaccine response2023
- Author(s)
  Nakagama Sachie、Nakagama Yu、Komase Yuko、Kudo Masaharu、Imai Takumi、Tshibangu-Kabamba Evariste、Nitahara Yuko、Kaku Natsuko、Kido Yasutoshi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1-7
- DOI
  10.3389/fimmu.2023.1087473
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09078, KAKENHI-PROJECT-22K15927, KAKENHI-PROJECT-22K17352, KAKENHI-PROJECT-22KJ2622
[Journal Article] Characteristics of epitope dominance pattern and cross-variant neutralisation in 16 SARS-CoV-2 mRNA vaccine sera2023
- Author(s)
  Yasugi Mayo、Nakagama Yu、Kaku Natsuko、Nitahara Yuko、Hatanaka Noritoshi、Yamasaki Shinji、Kido Yasutoshi
- Journal Title
  
  Vaccine
  
  Volume: 41 Issue: 42 Pages: 6248-6254
- DOI
  10.1016/j.vaccine.2023.08.076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KJ2622, KAKENHI-PROJECT-22KK0279, KAKENHI-PROJECT-21K09078, KAKENHI-PROJECT-22K15927
[Journal Article] Antibody testing as the guide to our living with COVID-192022
- Author(s)
  KAKU Natsuko、NAKAGAMA Yu、NITAHARA Yuko、KIDO Yasutoshi
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis
  
  Volume: 33 Issue: 3 Pages: 338-346
- DOI
  10.2491/jjsth.33.338
- ISSN
  0915-7441, 1880-8808
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-21K09078
[Journal Article] Immunogenicity and safety of COVID-19 vaccine in lung cancer patients receiving anticancer treatment: A prospective multicenter cohort study2022
- Author(s)
  Nakashima Kei、Ishida Masayuki、Matsui Hiroki、Yoshida Chihiro、Nagai Tatsuya、Shiraga Minoru、Nakaoka Hiroshi、Otsuka Yoshihito、Nakagama Yu、Kaku Natsuko、Nitahara Yuko、Kido Yasutoshi、Hirota Yoshio
- Journal Title
  
  Human Vaccines & Immunotherapeutics
  
  Volume: 18 Issue: 6 Pages: 1-13
- DOI
  10.1080/21645515.2022.2140549
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09078, KAKENHI-PROJECT-22K15927
[Journal Article] Detecting Waning Serological Response with Commercial Immunoassays: 18-Month Longitudinal Follow-up of Anti-SARS-CoV-2 Nucleocapsid Antibodies2022
- Author(s)
  Nakagama Yu、Komase Yuko、Kaku Natsuko、Nitahara Yuko、Tshibangu-Kabamba Evariste、Tominaga Tomoyo、Tanaka Hiroko、Yokoya Tomoaki、Hosokawa Minako、Kido Yasutoshi
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 10 Issue: 4
- DOI
  10.1128/spectrum.00986-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09078, KAKENHI-PROJECT-22K17352
[Journal Article] Antibody Avidity Maturation Following Recovery From Infection or the Booster Vaccination Grants Breadth of SARS-CoV-2 Neutralizing Capacity2022
- Author(s)
  Nakagama Y、Candray K、Kaku N、Komase Y、Rodriguez-Funes M-V、Dominguez R、Tsuchida T、Kunishima H、Nagai E、Adachi E、Mumba N D 、Yamasue M、Komiya K、Hiramatsu K、Uemura N、Sugiura Y、Yasugi M、Yamagishi Y、Mikamo H、Shiraishi S、Izumo T、Nakagama S、Watanabe C、Nitahara Y、Tshibangu-Kabamba E、Kakeya H、Kido Y
- Journal Title
  
  The Journal of Infectious Diseases
  
  Volume: 227 Issue: 6 Pages: 780-787
- DOI
  10.1093/infdis/jiac492
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09078, KAKENHI-PROJECT-22K15927, KAKENHI-PROJECT-22K17352
[Journal Article] Kinetics of anti-SARS-CoV-2 antibody titer in healthy adults up to 6?months after BNT162b2 vaccination measured by two immunoassays: A prospective cohort study in Japan2022
- Author(s)
  Matsuura Tomoka、Fukushima Wakaba、Nakagama Yu、Kido Yasutoshi、Kase Tetsuo、Kondo Kyoko、Kaku Natsuko、Matsumoto Kazuhiro、Suita Asae、Komiya Eriko、Mukai Emiko、Nitahara Yuko、Konishi Ayako、Kasamatsu Ayane、Nakagami-Yamaguchi Etsuko、Ohfuji Satoko、Kaneko Yukihiro、Kaneko Akira、Kakeya Hiroshi、Hirota Yoshio
- Journal Title
  
  Vaccine
  
  Volume: 40 Issue: 38 Pages: 5631-5640
- DOI
  10.1016/j.vaccine.2022.08.018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09078
[Journal Article] A Dual-Antigen SARS-CoV-2 Serological Assay Reflects Antibody Avidity2022
- Author(s)
  Nakagama Yu、Nitahara Yuko、Kaku Natsuko、Tshibangu-Kabamba Evariste、Kido Yasutoshi
- Journal Title
  
  Journal of Clinical Microbiology
  
  Volume: 60 Issue: 2
- DOI
  10.1128/jcm.02262-21
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09078, KAKENHI-PROJECT-22K17352
[Journal Article] Longitudinal ventilatory ratio monitoring for COVID-19: its potential in predicting severity and assessing treatment response2021
- Author(s)
  Kaku Natsuko、Nakagama Yu、Shirano Michinori、Shinomiya Sari、Shimazu Kazuhiro、Yamazaki Katsuaki、Maehata Yoshito、Morita Ryo、Nitahara Yuko、Yamamoto Hiromasa、Mizobata Yasumitsu、Kido Yasutoshi
- Journal Title
  
  Critical Care
  
  Volume: 25 Issue: 1 Pages: 366-366
- DOI
  10.1186/s13054-021-03768-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09078
[Journal Article] High-Resolution Linear Epitope Mapping of the Receptor Binding Domain of SARS-CoV-2 Spike Protein in COVID-19 mRNA Vaccine Recipients2021
- Author(s)
  Nitahara Yuko、Nakagama Yu、Kaku Natsuko、Candray Katherine、Michimuko Yu、Tshibangu-Kabamba Evariste、Kaneko Akira、Yamamoto Hiromasa、Mizobata Yasumitsu、Kakeya Hiroshi、Yasugi Mayo、Kido Yasutoshi
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 9 Issue: 3
- DOI
  10.1128/spectrum.00965-21
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09078
[Presentation] SARS-CoV-2 mRNAワクチン接種後の接種間隔を長くすると、3回目および4回目接種後抗体価は上昇する2023
- Author(s)
  松浦知香、福島若葉、加瀬哲男、大藤さとこ、近藤亨子、吹田安佐詠、迎恵美子、小西絢子、笠松彩音、城戸康年、中釜悠、加来奈津子、掛屋弘、金子幸弘、廣田良夫
- Organizer
  第27回ワクチン学会
- Data Source
  KAKENHI-PROJECT-21K09078
[Presentation] SARS-CoV-2に対する血清抗体成熟化の臨床的意義2023
- Author(s)
  中釜悠, Candray Katherine, 中釜幸恵, 加来奈津子, 仁田原裕子, Tshibangu Evariste, 城戸康年
- Organizer
  日本小児科学会
- Data Source
  KAKENHI-PROJECT-21K09078
[Presentation] Covid-19パンデミックが医療システムへ及ぼした影響　日本、エルサルバドル、コンゴ民主共和国の医療従事者におけるSARS-CoV-2血清有病率の比較調査2022
- Author(s)
  中釜悠, チバング・エバリステ , カンドライ・カテリン , 加来奈津子, 中釜幸恵, 仁田原裕子, 金子明, マリア・ロドリゲス , リーナ・ドミンゲス , 城戸康年
- Organizer
  日本渡航医学会
- Data Source
  KAKENHI-PROJECT-21K09078
[Presentation] Avidity maturation favors convalescents over vaccinated individuals granting breadth in neutralizability and tolerance against SARS-CoV-2 variants2022
- Author(s)
  Natsuko Kaku, Yu Nakagama, Yuko Nitahara, Hiroshi Kakeya, Yasutoshi Kido
- Organizer
  ASM Microbe
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09078
[Presentation] Avidity Maturation Favors Convalescents Over Vaccinated Individuals Granting Breadth in Neutralizability and Tolerance Against SARS-CoV-2 Variants2022
- Author(s)
  Natsuko Kaku, Yu Nakagama, Yuko Nitahara, Yasutoshi Kido
- Organizer
  ASM microbe
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09078
[Presentation] COVID-19のワクチン接種後抗体に及ぼす年齢の影響2022
- Author(s)
  中釜幸恵, 中釜悠, 駒瀬裕子, 工藤正治, 今井匠, 仁田原裕子, 加来奈津子, チバング・エバリステ , 城戸康年
- Organizer
  日本渡航医学会
- Data Source
  KAKENHI-PROJECT-21K09078
[Presentation] 抗体アビディティー成熟の観点からみた、SARS-CoV-2ワクチン誘導免疫と自然感染による免疫の差異2022
- Author(s)
  中釡悠, カンドライ・カテリン , 加来奈津子, チバング・エバリステ , 仁田原裕子, 城戸康年
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-21K09078
[Presentation] COVID-19 mRNAワクチン接種者におけるSARS-CoV-2スパイクタンパク質受容体結合ドメインの高解像度線形エピトープマッピング解析2021
- Author(s)
  仁田原裕子 , 中釜悠 , 加来奈津子 , Tshibangu-Kabamba Evariste , 金子明 , 安木真世 , 城戸康年
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K09078

1. 安達英輔 (80725804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 中村ふくみ (90295204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAKU Natsuko 加来 奈津子

Kaku Natsuko 加来 奈津子

Research Projects

Research Products

Co-Researchers

潜在的感染拡大を明らかにするハイリスク集団におけるMpox血清疫学Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of Epitopes Targeted by Neutralizing Antibodies Against SARS-CoV-2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Factors impacting antibody kinetics, including fever and vaccination intervals, in SARS-CoV-2-na?ve adults receiving the first four mRNA COVID-19 vaccine doses2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Age-adjusted impact of prior COVID-19 on SARS-CoV-2 mRNA vaccine response2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characteristics of epitope dominance pattern and cross-variant neutralisation in 16 SARS-CoV-2 mRNA vaccine sera2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antibody testing as the guide to our living with COVID-192022

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Immunogenicity and safety of COVID-19 vaccine in lung cancer patients receiving anticancer treatment: A prospective multicenter cohort study2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detecting Waning Serological Response with Commercial Immunoassays: 18-Month Longitudinal Follow-up of Anti-SARS-CoV-2 Nucleocapsid Antibodies2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antibody Avidity Maturation Following Recovery From Infection or the Booster Vaccination Grants Breadth of SARS-CoV-2 Neutralizing Capacity2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Kinetics of anti-SARS-CoV-2 antibody titer in healthy adults up to 6?months after BNT162b2 vaccination measured by two immunoassays: A prospective cohort study in Japan2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Dual-Antigen SARS-CoV-2 Serological Assay Reflects Antibody Avidity2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Longitudinal ventilatory ratio monitoring for COVID-19: its potential in predicting severity and assessing treatment response2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High-Resolution Linear Epitope Mapping of the Receptor Binding Domain of SARS-CoV-2 Spike Protein in COVID-19 mRNA Vaccine Recipients2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] SARS-CoV-2 mRNAワクチン接種後の接種間隔を長くすると、3回目および4回目 接種後抗体価は上昇する2023

Author(s)

Organizer

Data Source

[Presentation] SARS-CoV-2に対する血清抗体成熟化の臨床的意義2023

Author(s)

KAKU Natsuko 加来奈津子

Kaku Natsuko 加来奈津子

[Presentation] SARS-CoV-2 mRNAワクチン接種後の接種間隔を長くすると、3回目および4回目接種後抗体価は上昇する2023

[Presentation] Covid-19パンデミックが医療システムへ及ぼした影響　日本、エルサルバドル、コンゴ民主共和国の医療従事者におけるSARS-CoV-2血清有病率の比較調査2022