WATANABE Kazuki 渡辺数基

… Alternative Names

渡辺数基ワタナベカズキ

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Researcher Number	10908073
Other IDs
Affiliation (Current)	2025: 東北大学, 加齢医学研究所, 助教
Affiliation (based on the past Project Information) *help	2025: 東北大学, 加齢医学研究所, 助教 2023: 公立小松大学, 保健医療学部, 特別研究員 2022 – 2023: 東京医科歯科大学, 教養部, 非常勤講師
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related Except Principal Investigator Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator グルコース代謝 / 脳 / インスリン抵抗性 / 歯周病 / 糖尿病 / 認知症 Except Principal Investigator ＡＭＫ / 機能性食品 / マウス / 記憶力改善 … More / 2OH-メラトニン / AFMK / RNA-seq / LC/MS/MS / 記憶 / 加齢 / 海馬 / メラトニン / AMK Less

メラトニン代謝産物AMKによる脳内炎症制御に着目した新たな認知症予防基盤の構築Principal Investigator
- Principal Investigator
  
  渡辺数基
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tohoku University
歯周病が脳のインスリン抵抗性及び認知機能障害に与える影響とそのメカニズムの解明Principal Investigator
- Principal Investigator
  
  渡辺数基
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Komatsu University
長期記憶誘導効果をもつメラトニン代謝産物AMKの加齢変化と機能性食品への展開
- Principal Investigator
  
  服部淳彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Rikkyo University
  Tokyo Medical and Dental University

All 2024 2023 2022

All Journal Article Presentation

[Journal Article] N1‐Acetyl‐5‐methoxykynuramine, which decreases in the hippocampus with aging, improves long‐term memory via CaMKII/CREB phosphorylation2024
- Author(s)
  Watanabe Kazuki、Maruyama Yusuke、Iwashita Hikaru、Kato Haruyasu、Hirayama Jun、Hattori Atsuhiko
- Journal Title
  
  Journal of Pineal Research
  
  Volume: 76 Issue: 1
- DOI
  10.1111/jpi.12934
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K16821, KAKENHI-PROJECT-22KJ2575, KAKENHI-PROJECT-22K11823, KAKENHI-PROJECT-20K17520
[Journal Article] Analysis of Seawater Toxicity at Five Concentrated Seawater Discharge Sites in Korea Using a Goldfish Scale-Based In Vitro Bioassay System2023
- Author(s)
  Chun-Sang H Kuroda K Sato M Hatano K Watanabe K Hirayama J Sakatoku A Toyota K Rafiuddin MA Matsubara H Honda M Srivastav AK Sungjong L Suzuki N
- Journal Title
  
  Intern. J. Biol. Environ. Invest.
  
  Volume: 3 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K16821
[Journal Article] Inhabiting Tubes of Beard Worms Discovered in the Deep Sea of Toyama Bay, Japan2023
- Author(s)
  Shouzo Ogiso、Shion Ohshima、Hiroyuki Mishima、Kaito Hatano、Tomoki Takahashi、Hideto Tsutsui、Yasuhiro4 Morii、Nobuhiro Yamawaki、Ajai K Srivastav、Hajime Matsubara、Kazuki Watanabe、Jun Hirayama、Atsuhiko Hattori、Nobuo Suzuki
- Journal Title
  
  International Journal of Zoological Investigations
  
  Volume: 9 Issue: 2 Pages: 486-491
- DOI
  10.33745/ijzi.2023.v09i02.055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K16821
[Journal Article] Melatonin is more effective on bone metabolism when given at early night than during the day in ovariectomized rats2023
- Author(s)
  Miki Yukari、Seki Azusa、Mishima Hiroyuki、Maruyama Yusuke、Watanabe Kazuki、Kobayashi-Sun Jingjing、Kobayashi Isao、Kuroda Kohei、Oshima Shion、Okamoto Takeru、Matsubara Hajime、Srivastav Ajai K .、Tabuchi Yoshiaki、Hirayama Jun、Hattori Atsuhiko、Suzuki Nobuo
- Journal Title
  
  Melatonin Research
  
  Volume: 6 Issue: 2 Pages: 161-172
- DOI
  10.32794/mr112500147
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K16821, KAKENHI-PROJECT-22K11823, KAKENHI-PROJECT-23K10933, KAKENHI-PROJECT-23K11802
[Journal Article] daptation to the shallow sea floor environment of a species of marine worms, Oligobrachia mashikoi, generally inhabiting deep-sea water.2023
- Author(s)
  Shouzo Ogiso, Kazuki Watanabe, Yusuke Maruyama, Hiroshi Miyake, Kaito Hatano, Jun Hirayama, Atsuhiko Hattori, Yukina Watabe, Toshio Sekiguchi, Yoichiro Kitani, Yukihiro Furusawa, Yoshiaki Tabuchi, Hajime Matsubara, Mana Nakagiri, Kenji Toyota, Yuichi Sasayama, Nobuo Suzuki.
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 6299-6299
- DOI
  10.1038/s41598-023-33309-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15163, KAKENHI-PROJECT-20H04565, KAKENHI-PROJECT-23K16821, KAKENHI-PROJECT-22KJ2575, KAKENHI-PROJECT-22K11823, KAKENHI-PROJECT-23K05844, KAKENHI-PROJECT-21K05725
[Journal Article] Data on plasma cortisol levels in nibbler fish Girella punctata reared under high-density conditions in either surface seawater or deep ocean water2023
- Author(s)
  Ikari Takahiro、Hirayama Jun、Rafiuddin Muhammad Ahya、Furusawa Yukihiro、Tabuchi Yoshiaki、Watanabe Kazuki、Hattori Atsuhiko、Kawashima Ryotaro、Nakamura Kitaro、Srivastav Ajai K.、Toyota Kenji、Matsubara Hajime、Suzuki Nobuo
- Journal Title
  
  Data in Brief
  
  Volume: 49 Pages: 109361-109361
- DOI
  10.1016/j.dib.2023.109361
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KJ2575, KAKENHI-PROJECT-22K11823, KAKENHI-PROJECT-21K05725, KAKENHI-PROJECT-21K15163
[Journal Article] Kynurenine promotes Calcitonin secretion and reduces cortisol in the Japanese flounder Paralichthys olivaceus2023
- Author(s)
  Ikari T、Furusawa Y、Tabuchi Y、Maruyama Y、Hattori A、Kitani Y、Toyota K、Nagami A、Hirayama J、Watanabe K、Shigematsu A、Rafiuddin Muhammad Ahya、Ogiso S、Fukushi K、Kuroda K、Hatano K、Sekiguchi T、Kawashima R、Srivastav AK.、Nishiuchi T、Sakatoku A、Yoshida M、Matsubara H、Suzuki N
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 8700-8700
- DOI
  10.1038/s41598-023-35222-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K16821, KAKENHI-PROJECT-22KJ2575, KAKENHI-PROJECT-22K11823, KAKENHI-PROJECT-23K05844, KAKENHI-PROJECT-21K05725, KAKENHI-PROJECT-21K15163, KAKENHI-PROJECT-20H00630
[Journal Article] Nocturnal melatonin increases glucose uptake via insulin-independent action in the goldfish brain2023
- Author(s)
  Watanabe Kazuki、Nakano Masaki、Maruyama Yusuke、Hirayama Jun、Suzuki Nobuo、Hattori Atsuhiko
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 14 Pages: 1173113-1173113
- DOI
  10.3389/fendo.2023.1173113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K16821, KAKENHI-PROJECT-22KJ2575, KAKENHI-PROJECT-22K11823
[Journal Article] The use of biosignal measurements for circadian clock evaluation2023
- Author(s)
  Kawashima R , Suzuki I , Watanabe K , Fukuda T , Nogawa M , Hirayama J
- Journal Title
  
  Advances in Health and Disease. (Edited by Lowell T. Duncan) Nova Science Publishers.
  
  Volume: 66 Pages: 107-129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K16821
[Journal Article] Stanniocalcin in the Corpuscles of Stannius Inhibits the Osteoclastic Activation by Regulating the Rankl/Opg Expression2023
- Author(s)
  Kouhei Kuroda Ajai K. Srivastav Akiko Suzuki Muhammad Ahya Rafiuddin Kenji Toyota Masato Endo Masato Honda Kazuki Watanabe Yusuke Maruyama Yoshiaki Tabuchi Atsuhiko Hattori Makoto Urata Hajime Matsubara Nobuo Suzuki
- Journal Title
  
  Journal of Biological Regulators and Homeostatic Agents
  
  Volume: 37 Pages: 5141-5149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K16821
[Journal Article] Osteoclastic and Osteoblastic Responses to Hypergravity and Microgravity: Analysis Using Goldfish Scales as a Bone Model2022
- Author(s)
  Yamamoto Tatsuki、Ikegame Mika、Furusawa Yukihiro、Tabuchi Yoshiaki、Hatano Kaito、Watanabe Kazuki、Kawago Umi、Hirayama Jun、Yano Sachiko、Sekiguchi Toshio、Kitamura Kei-ichiro、Endo Masato、Nagami Arata、Matsubara Hajime、Maruyama Yusuke、Hattori Atsuhiko、Suzuki Nobuo
- Journal Title
  
  Zoological Science
  
  Volume: 39 Issue: 4 Pages: 388-396
- DOI
  10.2108/zs210107
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04565, KAKENHI-PROJECT-21K05725, KAKENHI-PROJECT-22K11823, KAKENHI-PROJECT-18K11016, KAKENHI-PROJECT-20K06718, KAKENHI-PROJECT-20K12619, KAKENHI-PROJECT-22KJ2575
[Presentation] 高血糖を引き起こしたキンギョの骨代謝に及ぼす影響2024
- Author(s)
  黒田康平, 丸山雄介, 渡辺数基, 遠藤雅人, 松原創, 田渕圭章, 平山順, 服部淳彦, 鈴木信雄
- Organizer
  令和6年度日本水産学会春季大会
- Data Source
  KAKENHI-PROJECT-22K11823
[Presentation] 記憶増強作用を持つメラトニン代謝産物 AMKの低用量長期投与が記憶形成能と血中生化学パラメーターに与える影響2023
- Author(s)
  渡辺数基, 丸山雄介, 平山順, 服部淳彦
- Organizer
  第23回日本抗加齢医学会
- Data Source
  KAKENHI-PROJECT-22K11823
[Presentation] メラトニン関連インドール化合物による最終糖化産物（AGEs）の架橋切断及び架橋形成阻害効果2023
- Author(s)
  丸山雄介, 渡辺数基, 加藤晴康, 服部淳彦
- Organizer
  第23回日本抗加齢医学会
- Data Source
  KAKENHI-PROJECT-22K11823
[Presentation] 糖尿病モデルラットにおける実験的歯周炎の治癒期の網羅的遺伝子発現解析2023
- Author(s)
  中川佳太, 水谷幸嗣, 渡辺数基, 齋藤夏実, 竹村修, 坂庭愛理, 三上理沙子, 城戸大輔, 武田浩平, 小湊広美, 服部淳彦, 岩田隆紀
- Organizer
  第66回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-23K16821
[Presentation] 夜間におけるアオゴカイの行動を制御するインドール化合物に関する研究2023
- Author(s)
  大嶋詩響, 小木曽正造, 豊田賢治, 渡辺数基, 平山順, 丸山雄介, 服部淳彦, 松原創, 鈴木信雄
- Organizer
  2023年度日本動物学会中部支部大会
- Data Source
  KAKENHI-PROJECT-22K11823
[Presentation] 高血糖により引き起こされる骨疾患を解析するための高血糖モデル魚の開発2023
- Author(s)
  黒田康平, 丸山雄介, 渡辺数基, 豊田賢治, 松原創, 平山順, 服部淳彦, 鈴木信雄
- Organizer
  第47回日本比較内分泌学会大会
- Data Source
  KAKENHI-PROJECT-23K16821
[Presentation] Social contexts mediate reward systems in a cricket Gryllus bimaculatus2023
- Author(s)
  Terao K, Kosaki Y, Maruyama Y, Watanabe K, Kataoka K, Hattori A, Matsumoto Y
- Organizer
  Non-Traditional Arthropod Model Systems: Studying Form and Function
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K16821
[Presentation] 海洋深層水に含まれる有機成分（キヌレニン）は海産魚のストレスを軽減する2023
- Author(s)
  鈴木信雄, 五十里雄大, 黒田康平, 端野開都, 渡辺数基, 平山順, 古澤之裕, 田渕圭章, 丸山雄介, 服部淳彦, 豊田賢治, 松原創
- Organizer
  第27回海洋深層水利用学会全国大会
- Data Source
  KAKENHI-PROJECT-22K11823
[Presentation] 高血糖により引き起こされる骨疾患を解析するための高血糖モデル魚の開発2023
- Author(s)
  黒田康平, 丸山雄介, 渡辺数基, 豊田賢治, 松原創, 平山順, 服部淳彦, 鈴木信雄
- Organizer
  第47回日本比較内分泌学会大会及びシンポジウム
- Data Source
  KAKENHI-PROJECT-22K11823
[Presentation] Effects of staniocalcin, a blood calcium-regulating hormone, on osteoblasts and osteoclasts in goldfish scales.2023
- Author(s)
  Kuroda, K , Srivastav, A.K , Suzuki, A , Rafiuddin, M.A , Toyota, K , Endo, M , Honda, M , Watanabe, K , Maruyama, Y , Tabuchi, Y , Hattori, A , Urata, M , Matsubara, H , Suzuki, N
- Organizer
  International Symposium: Environmental Issues in a Post-Covid 19 Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K16821
[Presentation] 記憶増強作用を持つメラトニン代謝産物AMKの低用量長期投与が記憶形成能と血中生化学パラメーターに与える影響2023
- Author(s)
  渡辺数基, 丸山雄介, 平山順, 服部淳彦
- Organizer
  第23回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-23K16821
[Presentation] 宇宙空間で引き起こされる骨疾患の治療薬の開発：キンギョのウロコ（骨モデル）及び骨疾患モデルラットを用いた解析2023
- Author(s)
  鈴木信雄, 古澤之裕, 田渕圭章, 豊田賢治, 関あずさ, 高垣裕子, 染井正徳, 江尻貞一, 池亀美華, 黒田康平, 丸山雄介, 渡辺数基, 関口俊男, 松原創, 髙橋昭久, 平山順, 服部淳彦
- Organizer
  2023年度日本動物学会中部支部大会
- Data Source
  KAKENHI-PROJECT-22K11823
[Presentation] メラトニン関連インドール化合物による最終糖化産物（AGEs）の架橋切断及び架橋形成阻害効果2023
- Author(s)
  丸山雄介, 渡辺数基, 加藤晴康, 服部淳彦
- Organizer
  第23回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-23K16821
[Presentation] 長期記憶誘導作用を持つメラトニン代謝産物 AMKの連続投与による記憶形成能への影響2022
- Author(s)
  丸山雄介, 渡辺数基, 服部淳彦
- Organizer
  第41回日本認知症学会
- Data Source
  KAKENHI-PROJECT-22K11823
[Presentation] 老齢マウスにおける内因性のメラトニン代謝産物AMK の変化と加齢に伴う記憶関連遺伝子の網羅的解析2022
- Author(s)
  渡辺数基, 丸山雄介, 服部淳彦
- Organizer
  第22回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-22K11823
[Presentation] 長期記憶誘導作用を持つメラトニン代謝産物AMKの加齢変化と記憶関連因子に与える影響2022
- Author(s)
  渡辺数基, 丸山雄介, 服部淳彦
- Organizer
  第41回日本認知症学会
- Data Source
  KAKENHI-PROJECT-22K11823
[Presentation] キンギョにおける学習・記憶試験 Object Recognition Test(ORT)の確立2022
- Author(s)
  毛利有沙, 田中美咲妃, 渡辺数基, 丸山雄介, 服部淳彦
- Organizer
  第46回日本比較内分泌学会大会及びシンポジウム
- Data Source
  KAKENHI-PROJECT-22K11823
[Presentation] 長期記憶を誘導するメラトニン代謝産物AMKはキンギョの脳における記憶形成関連因子を促進する2022
- Author(s)
  榊原和眞, 渡辺数基, 丸山雄介, 服部淳彦
- Organizer
  第46回日本比較内分泌学会大会及びシンポジウム
- Data Source
  KAKENHI-PROJECT-22K11823

1. 服部淳彦 (70183910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
2. FURUSAWA Yukihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 平山順

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 豊田賢治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

WATANABE Kazuki 渡辺 数基

渡辺 数基 ワタナベ カズキ

Research Projects

Research Products

Co-Researchers

メラトニン代謝産物AMKによる脳内炎症制御に着目した新たな認知症予防基盤の構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

歯周病が脳のインスリン抵抗性及び認知機能障害に与える影響とそのメカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

長期記憶誘導効果をもつメラトニン代謝産物AMKの加齢変化と機能性食品への展開

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] N1‐Acetyl‐5‐methoxykynuramine, which decreases in the hippocampus with aging, improves long‐term memory via CaMKII/CREB phosphorylation2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of Seawater Toxicity at Five Concentrated Seawater Discharge Sites in Korea Using a Goldfish Scale-Based In Vitro Bioassay System2023

Author(s)

Journal Title

Data Source

[Journal Article] Inhabiting Tubes of Beard Worms Discovered in the Deep Sea of Toyama Bay, Japan2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Melatonin is more effective on bone metabolism when given at early night than during the day in ovariectomized rats2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] daptation to the shallow sea floor environment of a species of marine worms, Oligobrachia mashikoi, generally inhabiting deep-sea water.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Data on plasma cortisol levels in nibbler fish Girella punctata reared under high-density conditions in either surface seawater or deep ocean water2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Kynurenine promotes Calcitonin secretion and reduces cortisol in the Japanese flounder Paralichthys olivaceus2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nocturnal melatonin increases glucose uptake via insulin-independent action in the goldfish brain2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The use of biosignal measurements for circadian clock evaluation2023

Author(s)

Journal Title

Data Source

[Journal Article] Stanniocalcin in the Corpuscles of Stannius Inhibits the Osteoclastic Activation by Regulating the Rankl/Opg Expression2023

Author(s)

Journal Title

Data Source

[Journal Article] Osteoclastic and Osteoblastic Responses to Hypergravity and Microgravity: Analysis Using Goldfish Scales as a Bone Model2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] 高血糖を引き起こしたキンギョの骨代謝に及ぼす影響2024

Author(s)

Organizer

Data Source

[Presentation] 記憶増強作用を持つメラトニン代謝産物 AMKの低用量長期投与が記憶形成能と血中生化学パラメーターに与える影響2023

WATANABE Kazuki 渡辺数基

渡辺数基ワタナベカズキ

[Presentation] 宇宙空間で引き起こされる骨疾患の治療薬の開発：キンギョのウロコ（骨モデル）及び骨疾患モデルラットを用いた解析2023