WU Chia-hsien 呉家賢

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WU CHIA-HSIEN 呉家賢

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Researcher Number	10908528
Other IDs
Affiliation (Current)	2026: 長崎大学, 医歯薬学総合研究科(医学系), 助教
Affiliation (based on the past Project Information) *help	2026: 長崎大学, 医歯薬学総合研究科(医学系), 助教 2022 – 2024: 長崎大学, 医歯薬学総合研究科(医学系), 助教
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Basic Section 53040:Nephrology-related Except Principal Investigator Basic Section 56050:Otorhinolaryngology-related
Keywords	Principal Investigator 生活習慣病 / 血管障害 / 長鎖ノンコーディングRNA / 動脈硬化 / 血管内皮細胞 / 内皮細胞 / 血管内皮健常性 Except Principal Investigator 瘢痕声帯 / 粘膜固有層 / 声帯筋 / 炎症反応 / 放射線 / マクロファージ

迷走神経による腎臓制御システムの解明Principal Investigator
- Principal Investigator
  
  呉家賢
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Nagasaki University
マクロファージを標的とした、放射線照射後声帯炎の予防に関する基礎的研究
- Principal Investigator
  
  熊井良彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Nagasaki University
動脈硬化好発領域における新規lncRNAの役割解明および機能解析Principal Investigator
- Principal Investigator
  
  呉家賢
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Nagasaki University
Investigate the role of a novel long non-coding RNA in the pathogenesis of atherosclerosisPrincipal Investigator
- Principal Investigator
  
  WU CHIA-HSIEN
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Nagasaki University

All 2025 2024 2023 2022

All Journal Article Presentation

[Journal Article] Swallowing-related muscle inflammation and fibrosis induced by a single dose of radiation exposure in mice2024
- Author(s)
  Soejima Shuntaro、Wu Chia-Hsien、Matsuse Haruna、Terakado Mariko、Okano Shinji、Inoue Tsuyoshi、Kumai Yoshihiko
- Journal Title
  
  Laboratory Animal Research
  
  Volume: 40 Issue: 1 Pages: 12-12
- DOI
  10.1186/s42826-024-00199-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24350, KAKENHI-PROJECT-24K19036
[Journal Article] Gravitational change-induced alteration of the vestibular function and gene expression in the vestibular ganglion of mice2024
- Author(s)
  Bazek Murat、Sawa Motoya、Horii Kazuhiro、Nakamura Naotoshi、Iwami Shingo、Wu Chia-Hsien、Inoue Tsuyoshi、Nin Fumiaki、Abe Chikara
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 74 Issue: 1 Pages: 44-44
- DOI
  10.1186/s12576-024-00939-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24350, KAKENHI-PROJECT-22K19617, KAKENHI-PROJECT-23K27997, KAKENHI-PROJECT-24K19036
[Journal Article] Activation of the α7nAChR by GTS-21 mitigates septic tubular cell injury and modulates macrophage infiltration2024
- Author(s)
  Yang Aobing、Wu Chia-Hsien、Matsuo Sayumi、Umene Ryusuke、Nakamura Yasuna、Inoue Tsuyoshi
- Journal Title
  
  International Immunopharmacology
  
  Volume: 138 Pages: 112555-112555
- DOI
  10.1016/j.intimp.2024.112555
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24350, KAKENHI-PROJECT-23K15251, KAKENHI-PROJECT-24K19036, KAKENHI-PROJECT-24K23464
[Journal Article] Renal macrophages induce hypertension and kidney fibrosis in Angiotensin II salt mice model2024
- Author(s)
  Peter Joseph Kasyoki、Umene Ryusuke、Wu Chia-Hsien、Nakamura Yasuna、Washimine Norito、Yamamoto Ryoko、Ngugi Caroline、Linge Kavoo、Kweri Joseph K.、Inoue Tsuyoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 715 Pages: 149997-149997
- DOI
  10.1016/j.bbrc.2024.149997
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24350, KAKENHI-PROJECT-23K15251, KAKENHI-PROJECT-24K19036
[Journal Article] Bone marrow stromal cell antigen-1 deficiency protects from acute kidney injury2024
- Author(s)
  Inoue Tsuyoshi、Umene Ryusuke、Sung Sun-Sang J.、Tanaka Shinji、Huang Liping、Yao Junlan、Hashimoto Noritatsu、Wu Chia-Hsien、Nakamura Yasuna、Nishino Tomoya、Ye Hong、Rosin Diane L.、Ishihara Katsuhiko、Okusa Mark D.
- Journal Title
  
  American Journal of Physiology-Renal Physiology
  
  Volume: 326 Issue: 2 Pages: F167-F177
- DOI
  10.1152/ajprenal.00175.2023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15251, KAKENHI-PROJECT-22K16107, KAKENHI-PROJECT-23K24350
[Journal Article] Induction of tetraspanin 13 contributes to the synergistic anti-inflammatory effects of parasympathetic and sympathetic stimulation in macrophages2023
- Author(s)
  Umene Ryusuke、Nakamura Yasuna、Wu Chia-Hsien、Muta Kumiko、Nishino Tomoya、Inoue Tsuyoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 665 Pages: 187-194
- DOI
  10.1016/j.bbrc.2023.04.118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16107, KAKENHI-PROJECT-21K20874, KAKENHI-PROJECT-22K16222, KAKENHI-PROJECT-23K24350
[Journal Article] Alpha 7 nicotinic acetylcholine receptors signaling boosts cell-cell interactions in macrophages effecting anti-inflammatory and organ protection2023
- Author(s)
  Nakamura Yasuna、Matsumoto Hirotaka、Wu Chia-Hsien、Fukaya Daichi、Uni Rie、Hirakawa Yosuke、Katagiri Mikako、Yamada Shintaro、Ko Toshiyuki、Nomura Seitaro、Wada Youichiro、Komuro Issei、Nangaku Masaomi、Inagi Reiko、Inoue Tsuyoshi
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 666-666
- DOI
  10.1038/s42003-023-05051-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16107, KAKENHI-PROJECT-20KK0174, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-23K22779, KAKENHI-PROJECT-23K24350, KAKENHI-PROJECT-22H00471
[Journal Article] Activation of α7 nicotinic acetylcholine receptors attenuates monocyte endothelial adhesion through FUT7 inhibition2022
- Author(s)
  Wu Chia-Hsien、Inoue Tsuyoshi、Nakamura Yasuna、Uni Rie、Hasegawa Sho、Maekawa Hiroshi、Sugahara Mai、Wada Youichiro、Tanaka Tetsuhiro、Nangaku Masaomi、Inagi Reiko
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 590 Pages: 89-96
- DOI
  10.1016/j.bbrc.2021.12.094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17242, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-21K19439, KAKENHI-PROJECT-21K16159, KAKENHI-PROJECT-21K20874, KAKENHI-PROJECT-22K16107
[Journal Article] The down-regulation of XBP1, an unfolded protein response effector, promotes acute kidney injury to chronic kidney disease transition2022
- Author(s)
  Chen Jia-Huang、Wu Chia-Hsien、Jheng Jia-Rong、Chao Chia-Ter、Huang Jenq-Wen、Hung Kuan-Yu、Liu Shing-Hwa、Chiang Chih-Kang
- Journal Title
  
  Journal of Biomedical Science
  
  Volume: 29 Issue: 1 Pages: 46-46
- DOI
  10.1186/s12929-022-00828-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16107
[Presentation] Defining Acetylcholine-Secreting Renal Cells and Their Function in Vagus Nerve Stimulation Using scRNA-Seq2025
- Author(s)
  呉家賢
- Organizer
  Nagasaki-Taiwan Medical Symposium
- Data Source
  KAKENHI-PROJECT-24K19036
[Presentation] 新規長鎖ノンコーディング RNA による血管内皮機能調節の解析2025
- Author(s)
  呉家賢
- Organizer
  第１０２回日本生理学会
- Data Source
  KAKENHI-PROJECT-24K19036
[Presentation] Being a Faculty in Japan: Exploring the Roles of Vagus Nerve Stimulation in Kidney Injury and Atherosclerosis2024
- Author(s)
  呉家賢
- Organizer
  台湾国立中興大学生命科学院　特別講演
- Invited
- Data Source
  KAKENHI-PROJECT-24K19036
[Presentation] Establishment of fractionated radiation induced vocal fold inflammation and fibrosis model in mouse2024
- Author(s)
  Haruna Matsuse, Shuntaro Soejima, Chia-Hsien Wu, Mariko Terakado, Okano Shinji, Tsuyoshi Inoue, Yoshihiko Kumai
- Organizer
  ヨーロッパ耳鼻咽喉科学会　CEORL2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K12719
[Presentation] 長鎖lncRNAによる動脈硬化進展抑制機構についての検討2023
- Author(s)
  呉家賢 (Wu Chia-Hsien)、井上　剛
- Organizer
  第74回西日本生理学会
- Data Source
  KAKENHI-PROJECT-22K16107
[Presentation] Activation of cholinergic anti-inflammatory pathway attenuates monocyte-endothelial adhesion through FUT7 inhibition2022
- Author(s)
  呉家賢, 井上剛
- Organizer
  第73回西日本生理学会
- Data Source
  KAKENHI-PROJECT-22K16107

1. 熊井良彦 (00555774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 井上剛 (30821665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. 副島駿太郎 (60901030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 安部力

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 中村恭菜

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

WU Chia-hsien 呉 家賢

WU CHIA-HSIEN 呉 家賢

Research Projects

Research Products

Co-Researchers

迷走神経による腎臓制御システムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マクロファージを標的とした、放射線照射後声帯炎の予防に関する基礎的研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

動脈硬化好発領域における新規lncRNAの役割解明および機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigate the role of a novel long non-coding RNA in the pathogenesis of atherosclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Swallowing-related muscle inflammation and fibrosis induced by a single dose of radiation exposure in mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gravitational change-induced alteration of the vestibular function and gene expression in the vestibular ganglion of mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of the α7nAChR by GTS-21 mitigates septic tubular cell injury and modulates macrophage infiltration2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Renal macrophages induce hypertension and kidney fibrosis in Angiotensin II salt mice model2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bone marrow stromal cell antigen-1 deficiency protects from acute kidney injury2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Induction of tetraspanin 13 contributes to the synergistic anti-inflammatory effects of parasympathetic and sympathetic stimulation in macrophages2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Alpha 7 nicotinic acetylcholine receptors signaling boosts cell-cell interactions in macrophages effecting anti-inflammatory and organ protection2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of α7 nicotinic acetylcholine receptors attenuates monocyte endothelial adhesion through FUT7 inhibition2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The down-regulation of XBP1, an unfolded protein response effector, promotes acute kidney injury to chronic kidney disease transition2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Defining Acetylcholine-Secreting Renal Cells and Their Function in Vagus Nerve Stimulation Using scRNA-Seq2025

Author(s)

Organizer

Data Source

[Presentation] 新規長鎖ノンコーディング RNA による血管内皮機能調節の解析2025

Author(s)

WU Chia-hsien 呉家賢

WU CHIA-HSIEN 呉家賢