Hiraizumi Masahiro 平泉将浩

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平泉将浩ヒライズミマサヒロ

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Researcher Number	10972317
Other IDs
Affiliation (Current)	2026: 東京大学, 大学院工学系研究科(工学部), 助教
Affiliation (based on the past Project Information) *help	2026: 東京大学, 大学院工学系研究科(工学部), 助教 2023 – 2024: 東京大学, 大学院工学系研究科(工学部), 助教
Review Section/Research Field	Principal Investigator Basic Section 43020:Structural biochemistry-related / Transformative Research Areas, Section (III)
Keywords	Principal Investigator クライオ電子顕微鏡 / ゲノム編集 / トランスポゾン / CRISPR-Casシステム

次世代ゲノム編集技術創出に向けたブリッジRNAの作動原理とその多様性の解明Principal Investigator
- Principal Investigator
  
  平泉将浩
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  The University of Tokyo
ブリッジRNAによるゲノム攪乱メカニズムの解明と次世代ゲノム編集技術への応用展開Principal Investigator
- Principal Investigator
  
  平泉将浩
- Project Period (FY)
  2026 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
CRISPRトランスポゼースCAST複合体によるDNA挿入機構の解明Principal Investigator
- Principal Investigator
  
  平泉将浩
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  The University of Tokyo

All 2025 2024

All Journal Article Presentation

[Journal Article] Rapid in silico directed evolution by a protein language model with EVOLVEpro2025
- Author(s)
  Jiang Kaiyi、Yan Zhaoqing、Di Bernardo Matteo、Sgrizzi Samantha R.、Villiger Lukas、Kayabolen Alisan、Kim B. J.、Carscadden Josephine K.、Hiraizumi Masahiro、Nishimasu Hiroshi、Gootenberg Jonathan S.、Abudayyeh Omar O.
- Journal Title
  
  Science
  
  Volume: 387 Issue: 6732 Pages: 377-377
- DOI
  10.1126/science.adr6006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14133
[Journal Article] Bridge RNAs direct programmable recombination of target and donor DNA2024
- Author(s)
  Durrant Matthew G.、Perry Nicholas T.、Pai James J.、Jangid Aditya R.、Athukoralage Januka S.、Hiraizumi Masahiro、McSpedon John P.、Pawluk April、Nishimasu Hiroshi、Konermann Silvana、Hsu Patrick D.
- Journal Title
  
  Nature
  
  Volume: 630 Issue: 8018 Pages: 984-993
- DOI
  10.1038/s41586-024-07552-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05281, KAKENHI-PROJECT-22H00403, KAKENHI-PROJECT-23K14133
[Journal Article] Transport and inhibition mechanism of the human SGLT2?MAP17 glucose transporter2024
- Author(s)
  Hiraizumi Masahiro、Akashi Tomoya、Murasaki Kouta、Kishida Hiroyuki、Kumanomidou Taichi、Torimoto Nao、Nureki Osamu、Miyaguchi Ikuko
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 31 Issue: 1 Pages: 159-169
- DOI
  10.1038/s41594-023-01134-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14133
[Journal Article] Structural mechanism of bridge RNA-guided recombination2024
- Author(s)
  Hiraizumi Masahiro、Perry Nicholas T.、Durrant Matthew G.、Soma Teppei、Nagahata Naoto、Okazaki Sae、Athukoralage Januka S.、Isayama Yukari、Pai James J.、Pawluk April、Konermann Silvana、Yamashita Keitaro、Hsu Patrick D.、Nishimasu Hiroshi
- Journal Title
  
  Nature
  
  Volume: 630 Issue: 8018 Pages: 994-1002
- DOI
  10.1038/s41586-024-07570-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05281, KAKENHI-PROJECT-22H00403, KAKENHI-PROJECT-23K14133
[Presentation] クライオ電子顕微鏡を用いた生体分子の単粒子構造解析2024
- Author(s)
  平泉　将浩
- Organizer
  第13回AAA（Academy of Aging and CArdiovascular-Diabetes Research）研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K14133
[Presentation] ブリッジ RNA が橋渡しする DNA 組換えメカニズム2024
- Author(s)
  平泉　将浩
- Organizer
  第30回日本遺伝子細胞治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K14133

1. NISHIMASU Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Hiraizumi Masahiro 平泉 将浩

平泉 将浩 ヒライズミ マサヒロ

Research Projects

Research Products

Co-Researchers

次世代ゲノム編集技術創出に向けたブリッジRNAの作動原理とその多様性の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ブリッジRNAによるゲノム攪乱メカニズムの解明と次世代ゲノム編集技術への応用展開Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

CRISPRトランスポゼースCAST複合体によるDNA挿入機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Rapid in silico directed evolution by a protein language model with EVOLVEpro2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bridge RNAs direct programmable recombination of target and donor DNA2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transport and inhibition mechanism of the human SGLT2?MAP17 glucose transporter2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural mechanism of bridge RNA-guided recombination2024

Author(s)

Journal Title

DOI

Data Source

[Presentation] クライオ電子顕微鏡を用いた生体分子の単粒子構造解析2024

Author(s)

Organizer

Data Source

[Presentation] ブリッジ RNA が橋渡しする DNA 組換えメカニズム2024

Author(s)

Organizer

Data Source

Hiraizumi Masahiro 平泉将浩

平泉将浩ヒライズミマサヒロ