Nagata Kazuki 長田和樹

… Alternative Names

長田和樹ナガタカズキ

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Researcher Number	10979537
Affiliation (Current)	2026: 東京理科大学, 先進工学部生命システム工学科, 助教
Affiliation (based on the past Project Information) *help	2023 – 2024: 東京理科大学, 先進工学部生命システム工学科, 助教
Review Section/Research Field	Principal Investigator Basic Section 38060:Applied molecular and cellular biology-related Except Principal Investigator Basic Section 38050:Food sciences-related
Keywords	Principal Investigator 腸管神経 / マスト細胞 / 神経免疫相互作用 / 食物アレルギー Except Principal Investigator Gタンパク質共役型受容体 / GPR109A/HCAR2 / GPR109A / アレルギー / 短鎖脂肪酸 / フラボノイド … More / 腸内細菌代謝産物 / ヒストン脱アセチル化酵素（HDAC）阻害活性 / 短鎖脂肪酸（SCFA） / 樹状細胞 / マスト細胞 Less

Regulation of mast cell activation and immune tolerance by food-related factors focusing on short-chain fatty acid
- Principal Investigator
  
  西山千春
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Tokyo University of Science
食物アレルギー病態における神経免疫相互作用の解明Principal Investigator
- Principal Investigator
  
  長田和樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Tokyo University of Science

All 2025 2024 2023

All Journal Article Presentation Patent

[Journal Article] PU.1 and TGF-β signaling transactivate CD103 expression in mast cells and dendritic cells: Opposite roles of GATA2 in the expression of mucosal mast cell-specific genes2025
- Author(s)
  Ishii Kenta、Nagata Kazuki、Akimoto Yuta、Zhao Weiting、Inoue Mariko、Ito Naoto、Kasakura Kazumi、Nishiyama Chiharu
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2025.02.10.637371
- Open Access
- Data Source
  KAKENHI-PROJECT-23K26860
[Journal Article] Transcriptional regulation of basophil‐specific protease genes by C/EBPα, GATA2, TGF‐β signaling, and epigenetic mechanisms2025
- Author(s)
  Tojima Ryotaro、Nagata Kazuki、Ito Naoto、Ishii Kenta、Arai Takahiro、Ito Tomoka、Kasakura Kazumi、Nishiyama Chiharu
- Journal Title
  
  FEBS Letters
  
  Volume: 599 Issue: 5 Pages: 777-786
- DOI
  10.1002/1873-3468.15069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K26860
[Journal Article] The role of GATA2 in the expression of the soluble decoy receptor ST2/IL1RL1 in human and mouse mast cells2025
- Author(s)
  Nagata Kazuki、Kasakura Kazumi、Ishii Kenta、Ito Naoto、Hara Mutsuko、Okumura Ko、Nishiyama Chiharu
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2025.02.19.638998
- Open Access
- Data Source
  KAKENHI-PROJECT-23K26860
[Journal Article] Kaempferol Exerts Anti‐Inflammatory Effects by Accelerating Treg Development via Aryl Hydrocarbon Receptor‐Mediated and PU.1/IRF4‐Dependent Transactivation of the Aldh1a2/Raldh2 Gene in Dendritic Cells2025
- Author(s)
 Takahashi Miki、Nagata Kazuki、Watanuki Yumi、Yamaguchi Masaki、Ishii Kenta、Harada Tomohiro、Minamikawa Natsuki、Katagiri Mayuka、Zhao Weiting、Ito Naoto、Yashiro Takuya、Nishiyama Chiharu
- Journal Title
 
 Allergy
 
 Volume: 80 Issue: 3 Pages: 896-900
- DOI
 10.1111/all.16410
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-23K26860
[Journal Article] Immunostimulatory effects of Heyndrickxia coagulans SANK702582024
- Author(s)
 Ikeda Yuki、Yamashita Niya、Ito Naoto、Minamikawa Natsuki、Okamura Hotaka、Yashiro Takuya、Hachisu Masakazu、Aida Masanori、Yamada Ryouichi、Nagata Kazuki、Nishiyama Chiharu
- Journal Title
 
 Bioscience, Biotechnology, and Biochemistry
 
 Volume: 89 Issue: 4 Pages: 622-632
- DOI
 10.1093/bbb/zbae203
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-21K05297, KAKENHI-PROJECT-23K26860
[Journal Article] NR4A3 deficiency ameliorates contact hypersensitivity and exacerbates psoriasis by regulating gene expression in dendritic cells2024
- Author(s)
  Katagiri Mayuka、Ito Naoto、Nagata Kazuki、Nakano Shiori、Minamikawa Natsuki、Yamashita Niya、Takahashi Miki、Kurihara Masami、Nagaoka Masanori、Ando Miki、Ito Tomoka、Yashiro Takuya、Yoshimura Akihiko、Nishiyama Chiharu
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2024.02.20.581116
- Open Access
- Data Source
  KAKENHI-PROJECT-23K26860
[Journal Article] Butyrate, Valerate, and Niacin Ameliorate Anaphylaxis by Suppressing IgE-Dependent Mast Cell Activation: Roles of GPR109A, PGE2, and Epigenetic Regulation2024
- Author(s)
  Nagata Kazuki、Ando Daisuke、Ashikari Tsubasa、Ito Kandai、Miura Ryosuke、Fujigaki Izumi、Goto Yuki、Ando Miki、Ito Naoto、Kawazoe Hibiki、Iizuka Yuki、Inoue Mariko、Yashiro Takuya、Hachisu Masakazu、Kasakura Kazumi、Nishiyama Chiharu
- Journal Title
  
  The Journal of Immunology
  
  Volume: 212 Issue: 5 Pages: 771-784
- DOI
  10.4049/jimmunol.2300188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05297, KAKENHI-PROJECT-23K26860
[Journal Article] The powerful potential of amino acid menthyl esters for anti‐inflammatory and anti‐obesity therapies2024
- Author(s)
  Takasawa Seidai、Kimura Kosuke、Miyanaga Masato、Uemura Takuya、Hachisu Masakazu、Miyagawa Shinichi、Ramadan Abdelaziz、Sukegawa Satoru、Kobayashi Masaki、Kimura Seisuke、Matsui Kenji、Shiroishi Mitsunori、Terashita Kaori、Nishiyama Chiharu、Yashiro Takuya、Nagata Kazuki、Higami Yoshikazu、Arimura Gen‐ichiro
- Journal Title
  
  Immunology
  
  Volume: 173 Issue: 1 Pages: 76-92
- DOI
  10.1111/imm.13798
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05297, KAKENHI-PROJECT-23K26833, KAKENHI-PROJECT-23K26860, KAKENHI-PROJECT-24K01723
[Journal Article] Roles of C/EBPα, GATA2, TGF-β-signaling, and epigenetic regulation in the expression of basophil-specific protease genes2024
- Author(s)
  Tojima Ryotaro、Nagata Kazuki、Ito Naoto、Arai Takahiro、Ishii Kenta、Ito Tomoka、Kasakura Kazumi、Nishiyama Chiharu
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2024.02.24.581851
- Open Access
- Data Source
  KAKENHI-PROJECT-23K26860
[Journal Article] The gut lactic acid bacteria metabolite, 10-oxo-cis-6,trans-11-octadecadienoic acid, suppresses inflammatory bowel disease in mice by modulating the NRF2 pathway and GPCR-signaling2024
- Author(s)
  Ando Miki、Nagata Kazuki、Takeshita Ryuki、Ito Naoto、Noguchi Sakura、Minamikawa Natsuki、Kodama Naoki、Yamamoto Asuka、Yashiro Takuya、Hachisu Masakazu、Ichihara Gaku、Kishino Shigenobu、Yamamoto Masayuki、Ogawa Jun、Nishiyama Chiharu
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 15 Pages: 1374425-1374425
- DOI
  10.3389/fimmu.2024.1374425
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05297, KAKENHI-PROJECT-23K26860, KAKENHI-PROJECT-23K27842, KAKENHI-PROJECT-24K22212, KAKENHI-PROJECT-23KF0276
[Journal Article] Kaempferol exerts anti-inflammatory effects by accelerating Treg development via AhR-mediated and PU.1/IRF4-dependent transactivation of theAldh1a2/RALDH2 gene in dendritic cells2024
- Author(s)
 Takahashi Miki、Nagata Kazuki、Watanuki Yumi、Yamaguchi Masaki、Minamikawa Natsuki、Katagiri Mayuka、Zhao Weiting、Ito Naoto、Yashiro Takuya、Nishiyama Chiharu
- Journal Title
 
 bioRxiv
 
 Volume: -
- DOI
 10.1101/2024.02.21.581328
- Open Access
- Data Source
 KAKENHI-PROJECT-23K26860
[Patent] 免疫調整効果に優れた食品素材及びそれを含む飲食品2024
- Inventor(s)
  西山千春、後藤有貴、長田和樹、平本忠浩、大田黒晴樹
- Industrial Property Rights Holder
  高砂香料工業株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-032037
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] プラズマサイトイド劇状細胞分化における転写因子PU.1とSpiBの役割とエピジェネティックな発現制御機構の解明2025
- Author(s)
  伊藤直人、平川真弓、趙維霆、南川夏己、片桐万由佳、三浦亮介、長田和樹、伊川友活、西山千春
- Organizer
  日本農芸化学会2025年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 芽胞形成乳酸産生細菌 Heyndrickxia coagulans SANK70258のpDC活性化能2025
- Author(s)
  岡村穂丘、伊藤直人、山下二矢、池田裕樹、長田和樹、相田正典、山田良一、西山千春
- Organizer
  日本農芸化学会2025年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] NR4A3欠損マウスにおける大腸炎関連結腸直腸癌の表現型解析2025
- Author(s)
  山下二矢、南川夏己、伊藤直人、片桐万由佳、長田和樹、吉村昭彦、西山千春
- Organizer
  日本農芸化学会2025年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] アレルギー反応に抵抗性を示すNrf2欠損マスト細胞の機能解析2025
- Author(s)
  野口桜花、芦刈翼、長田和樹、西山千春
- Organizer
  日本農芸化学会2025年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 経口免疫寛容における酪酸摂取の影響と作用機序の解明2025
- Author(s)
  長田和樹、西山千春
- Organizer
  日本農芸化学会2025年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Nrf2欠損による接触性皮膚炎の増悪化は、CD4+T細胞の増殖亢進やDC活性化亢進を介して雌で顕著化する2025
- Author(s)
  杉原彩夏、長田和樹、伊藤直人、時田隆世、西山千春
- Organizer
  日本農芸化学会2025年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Mcpt2発現細胞の欠損はアレルギー性喘息を促進し、アトピー性皮膚炎を抑制する2025
- Author(s)
  石井健大、川添響、長田和樹、西山千春
- Organizer
  日本農芸化学会2025年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 小胞体ストレス応答の阻害はIgE依存的なマスト細胞の活性化を抑制する2025
- Author(s)
  神田寛登、長田和樹、芦刈翼、西山千春
- Organizer
  日本農芸化学会2025年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 新たに見出した免疫抑制化合物のマスト細胞依存的アレルギー反応抑制効果2024
- Author(s)
  関健人、長田和樹、西山千春
- Organizer
  日本食品免疫学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Deficiency of the antioxidant stress response master transcription factor Nrf2 ameliorates IgE-induced anaphylaxis in mice by suppressing IgE-dependent activation of mast cells2024
- Author(s)
  Sakura Noguchi, Tsubasa Ashikari, Kazuki Nagata, and Chiharu Nishiyama
- Organizer
  The 53rd Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Regulatory mechanisms of gene expression and development of conventional dendritic cell and plasmacytoid dendritic cell by short-chain fatty acids2024
- Author(s)
  Weiting Zhao, Kazuki Nagata, Naoto Ito, Ryusei Tokita, Osamu Kaminuma, and Chiharu Nishiyama
- Organizer
  The 53rd Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] マスト細胞の活性化における小胞体ストレス応答の寄与2024
- Author(s)
  神田寛登、長田和樹、芦刈翼、西山千春
- Organizer
  第97回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] KaempferolによるRALDH2発現調節と食物アレルギー改善効果2024
- Author(s)
  高橋美貴、長田和樹、綿貫優実、山口昌樹、八代拓也、西山千春
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 樹状細胞の分化およびインテグリン遺伝子発現に対する短鎖脂肪酸の影響2024
- Author(s)
  趙維霆、長田和樹、伊藤直人、西山千春
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] I型アレルギー反応を標的とした新規免疫抑制化合物の開発2024
- Author(s)
  関健人、長田和樹、沼田向陽、坂田文弥、平野弘之、長田裕之、吉田優、西山千春
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Lactobacillus acidophilus L-92の免疫賦活作用：ヒト末梢血樹状細胞の活性化評価2024
- Author(s)
  神田寛登、伊藤直人、長田和樹、西山千春
- Organizer
  日本食品免疫学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 炎症性腸疾患に耐性を示す核内受容体型転写因子NR4A3欠損マウスの免疫応答と腸管構造2024
- Author(s)
  南川夏己、伊藤直人、片桐万由佳、中野信浩、原むつ子、樋上賀一、長田和樹、吉村昭彦、西山千春
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 大腸炎関連結腸直腸癌における核内受容体型転写因子NR4A3の寄与2024
- Author(s)
  山下二矢、南川夏己、伊藤直人、片桐万由佳、長田和樹、吉村昭彦、西山千春
- Organizer
  第97回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] NRF2欠損の胎内環境並びに性差が及ぼす接触性皮膚炎への影響2024
- Author(s)
  杉原彩夏、長田和樹、西山千春
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Immunosuppressive effect of perilla leaf aroma components2024
- Author(s)
  Ryusei Tokita, Naoto Ito, Hikaru Okada, Kazuki Nagata, and Chiharu Nishiyama
- Organizer
  The 53rd Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Weizmannia coagulans SANK70258の樹状細胞を介した免疫調節作用機構と経口摂取による腸管免疫への効果2024
- Author(s)
  山下二矢、伊藤直人、池田裕樹、南川夏己、八代拓也、八須匡和、長田和樹、相田正典、山田良一、西山千春
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Roles of transcription factor PU.1 and TGF-b-signaling in the regulation of CD103 expression in mucosal mast cells and dendritic cells2024
- Author(s)
  Kenta Ishii, Kazuki Nagata, and Chiharu Nishiyama
- Organizer
  The 53rd Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 抗酸化応答マスター転写因子NRF2の欠損が及ぼすマスト細胞への影響2024
- Author(s)
  野口桜花、長田和樹、杉原彩夏、芦刈翼、荒海咲苗、中野信浩、原むつ子、西山千春
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] NR4A3 deficiency deteriorates psoriasis by amplifying TLR7-mediated activation of dendritic cells2024
- Author(s)
  Mayuka Katagiri, Naoto Ito, Natsuki Minamikawa, Kazuki Nagata, Akihiko Yoshimura, and Chiharu Nishiyama
- Organizer
  The 52nd Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Kaempferol exhibits an anti-inflammatory effect through AhR-mediated upregulation of RALDH2 in dendritic cells2024
- Author(s)
  Miki Takahashi, Kazuki Nagata, Yumi Watanuki, Masaki Yamaguchi, Takuya Yashiro, Sakura Noguchi, and Chiharu Nishiyama
- Organizer
  The 52nd Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 好塩基球特異的プロテアーゼの遺伝子発現を制御する転写因子とエピジェネティック修飾2024
- Author(s)
  戸島遼太郎、長田和樹、新井貴大、伊藤直人、笠倉和巳、西山千春
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Effects of gender and prenatal environment on exacerbation of contact hypersensitivity in Nrf2-deficient mice2024
- Author(s)
  Ayaka Sugihara, Kazuki Nagata, and Chiharu Nishiyama
- Organizer
  The 53rd Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Roles of transcription factors PU.1 and SpiB and epigenetic regulation in commitment between conventional dendritic cells and plasmacytoid dendritic cells2024
- Author(s)
  Naoto Ito, Mayumi Hirakawa, Weiting Zhao, Natsuki Minamikawa, Mayuka Katagiri, Ryosuke Miura,, Kazuki Nagata, Tomokatsu Ikawa, and Chiharu Nishiyama
- Organizer
  The 53rd Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 性差がNrf2欠損マウスの接触性皮膚炎に及ぼす影響2024
- Author(s)
  杉原彩夏、長田和樹、伊藤直人、西山千春
- Organizer
  日本食品免疫学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 抗酸化応答マスター転写因子Nrf2の欠損はマスト細胞依存性アレルギー反応を減弱化する2024
- Author(s)
  野口桜花、長田和樹、杉原彩夏、芦刈翼、西山千春
- Organizer
  第97回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Roles of C/EBPalpha, GATA2, TGF-beta-signaling, and epigenetic regulation in expression of basophil-specific protease genes, Mcpt8 and Mcpt112024
- Author(s)
  Ryotaro Tojima, Takahiro Arai, Tomoka Ito, Naoto Ito, Kazumi Kasakura, Kazuki Nagata, and Chiharu Nishiyama
- Organizer
  The 52nd Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] マスト細胞における接着分子CD103の発現制御機構2024
- Author(s)
  石井健大、長田和樹、西山千春
- Organizer
  第97回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 酪酸はIgE非依存的マスト細胞活性化を抑制する2024
- Author(s)
  森田莉加、長田和樹、谷萩祐太、岡村穂丘、山崎憲政、三浦健人、神沼修、西山千春
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 生体由来マスト細胞における接着分子CD103の発現調節機構2024
- Author(s)
  石井健大、長田和樹、西山千春
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] アトピー性皮膚炎並びにアレルギー性喘息における粘膜型マスト細胞の寄与2024
- Author(s)
  石井健大、長田和樹、西山千春
- Organizer
  日本食品免疫学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] A novel immunomodulatory compound identified through a screening targeting dendritic cell ameliorates colitis and contact hypersensitivity in mice2024
- Author(s)
  Kazuki Nagata, Fumiya Sakata, Ayaka Sugihara, Miki Takahashi, Hiroyuki Hirano, Hiroyuki Osada, and Chiharu Nishiyama
- Organizer
  The 53rd Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 核内受容体NR4A3は樹状細胞の転写調節を制御し、その欠損は接触性皮膚炎の緩和と乾癬の増悪化をもたらす2024
- Author(s)
  片桐万由佳、伊藤直人、南川夏己、長田和樹、吉村昭彦、西山千春
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] ポリフェノールおよび酸化酵素含有製剤DEOATAK P1のヒト単球細胞に及ぼす効果2024
- Author(s)
  後藤有貴、長田和樹、片桐万由佳、神田寛登、時田隆世、大田黒晴樹、武田寿弘、平本忠浩、西山千春
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] シソ葉香気成分の免疫抑制効果2024
- Author(s)
  時田隆世、岡田光、伊藤直人、杉原彩夏、野口桜花、長田和樹、西山千春
- Organizer
  第97回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Deficiency of nuclear receptor Nr4a3 alleviates colitis-associated cancer in mice2024
- Author(s)
  Niya Yamashita, Natsuki Minamikawa, Naoto Ito, Mayuka Katagiri, Kazuki Nagata, Akihiko Yoshimura, and Chiharu Nishiyama
- Organizer
  The 53rd Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] The deficiency of transcription factor NR4A3 ameliorates inflammatory bowel disease2024
- Author(s)
  Natsuki Minamikawa, Naoto Ito, Mayuka Katagiri, Kazuki Nagata, Akihiko Yoshimura, and Chiharu Nishiyama
- Organizer
  The 52nd Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Nrf2欠損による接触性皮膚炎の増悪化には胎内環境や性差が関与する2024
- Author(s)
  杉原彩夏、長田和樹、西山千春
- Organizer
  第97回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Functional analysis of transcription factors PU.1 and SpiB in the determination of dendritic cell fate2024
- Author(s)
  Naoto Ito, Mayumi Hirakawa, Natsuki Minamikawa, Mayuka Katagiri, Kazuki Nagata, Tomokatsu Ikawa, and Chiharu Nishiyama
- Organizer
  The 52nd Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 酪酸はT細胞機能調節を介して皮膚疾患乾癬を改善する2024
- Author(s)
  時田隆世、廣木郁美、鈴木勝大、長田和樹、西山千春
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Roles of GATA3 in LPS-induced cytokine expression in mast cells2024
- Author(s)
  Yuki Goto, Kazuki Nagata, Hiromi Takeuchi, and Chiharu Nishiyama
- Organizer
  The 52nd Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] プラズマサイトイド樹状細胞の分化並びに遺伝子発現における転写因子PU.1とSpiBの役割2023
- Author(s)
  伊藤直人、平川真弓、南川夏己、片桐万由佳、長田和樹、伊川友活、西山千春
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Bacillus coagulans SANK70258の樹状細胞活性化機構の解析と経口摂取の生理活性評価2023
- Author(s)
  山下ニ矢、伊藤直人、池田裕樹、南川夏己、八代拓也、八須匡和、長田和樹、西山千春
- Organizer
  日本食品免疫学会20223年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] IgE依存的アレルギー反応における抗酸化ストレス応答マスター転写因子NRF2の役割2023
- Author(s)
  野口桜花、芦刈翼、長田和樹、西山千春
- Organizer
  日本食品免疫学会20223年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] フラボノール類Kaempferolの抗アレルギー効果2023
- Author(s)
  高橋美貴、長田和樹、荒海咲苗、野口桜花、南川夏己、西山千春
- Organizer
  日本食品免疫学会20223年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] フラボノール類ポリフェノールKaempferolの免疫調節作用2023
- Author(s)
  高橋美貴、長田和樹、綿貫優実、山口昌樹、八代拓也、西山千春
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 短鎖脂肪酸は樹状細胞の分化や接着分子発現を促進し腸管樹状細胞の局在を制御する2023
- Author(s)
  趙維霆、長田和樹、伊藤直人、西山千春
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] Bacillus coagulans SANK70258の免疫調節作用2023
- Author(s)
  山下二矢、伊藤直人、池田裕樹、南川夏己、八代拓也、八須匡和、相田正典、山田良一、長田和樹、西山千春
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 好塩基球とマスト細胞の特異的遺伝子発現を制御する転写因子とエピジェネティック修飾2023
- Author(s)
  戸島遼太郎、長田和樹、新井貴大、伊藤直人、笠倉和巳、西山千春
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 神経-免疫経路の調節を介したκオピオイドの食物アレルギー改善効果2023
- Author(s)
  長田和樹、長瀬博、西山千春
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 分岐鎖脂肪酸によるマスト細胞の活性化調節機構2023
- Author(s)
  後藤有貴、飯塚雄輝、長田和樹、西山千春
- Organizer
  日本食品免疫学会20223年度大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 核内受容体型転写因子NR4A3の欠損は樹状細胞のTLR7発現増強を介して乾癬を増悪化する2023
- Author(s)
  片桐万由佳、伊藤直人、南川夏己、長田和樹、吉村昭彦、西山千春
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] マスト細胞のサイトカイン発現における転写因子GATA3の役割2023
- Author(s)
  後藤有貴、長田和樹、竹内裕美、西山千春
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] 炎症性腸疾患の病態形成における核内受容体型転写因子NR4A3の役割2023
- Author(s)
  南川夏己、伊藤直人、片桐万由佳、長田和樹、吉村昭彦、西山千春
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K26860
[Presentation] PAMP依存的マスト細胞活性化に及ぼす短鎖脂肪酸の作用2023
- Author(s)
  森田莉加、長田和樹、西山千春
- Organizer
  日本食品免疫学会20223年度大会
- Data Source
  KAKENHI-PROJECT-23K26860

1. 西山千春 (20327836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 66 results
2. 八須匡和 (60587442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

Nagata Kazuki 長田 和樹

長田 和樹 ナガタ カズキ

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Regulation of mast cell activation and immune tolerance by food-related factors focusing on short-chain fatty acid

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食物アレルギー病態における神経免疫相互作用の解明Principal Investigator

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[Journal Article] PU.1 and TGF-β signaling transactivate CD103 expression in mast cells and dendritic cells: Opposite roles of GATA2 in the expression of mucosal mast cell-specific genes2025

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[Journal Article] Transcriptional regulation of basophil‐specific protease genes by C/EBPα, GATA2, TGF‐β signaling, and epigenetic mechanisms2025

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[Journal Article] The role of GATA2 in the expression of the soluble decoy receptor ST2/IL1RL1 in human and mouse mast cells2025

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[Journal Article] Kaempferol Exerts Anti‐Inflammatory Effects by Accelerating Treg Development via Aryl Hydrocarbon Receptor‐Mediated and PU.1/IRF4‐Dependent Transactivation of the <i>Aldh1a2</i>/Raldh2 Gene in Dendritic Cells2025

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[Journal Article] Immunostimulatory effects of <i>Heyndrickxia coagulans</i> SANK702582024

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[Journal Article] NR4A3 deficiency ameliorates contact hypersensitivity and exacerbates psoriasis by regulating gene expression in dendritic cells2024

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[Journal Article] Butyrate, Valerate, and Niacin Ameliorate Anaphylaxis by Suppressing IgE-Dependent Mast Cell Activation: Roles of GPR109A, PGE2, and Epigenetic Regulation2024

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[Journal Article] The powerful potential of amino acid menthyl esters for anti‐inflammatory and anti‐obesity therapies2024

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[Journal Article] Roles of C/EBPα, GATA2, TGF-β-signaling, and epigenetic regulation in the expression of basophil-specific protease genes2024

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[Journal Article] The gut lactic acid bacteria metabolite, 10-oxo-cis-6,trans-11-octadecadienoic acid, suppresses inflammatory bowel disease in mice by modulating the NRF2 pathway and GPCR-signaling2024

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[Journal Article] Kaempferol exerts anti-inflammatory effects by accelerating Treg development via AhR-mediated and PU.1/IRF4-dependent transactivation of the<i>Aldh1a2/</i>RALDH2 gene in dendritic cells2024

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[Patent] 免疫調整効果に優れた食品素材及びそれを含む飲食品2024

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[Presentation] プラズマサイトイド劇状細胞分化における転写因子PU.1とSpiBの役割とエピジェネティックな発現制御機構の解明2025

Nagata Kazuki 長田和樹

長田和樹ナガタカズキ