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Higuchi Makio  樋口 牧郎

ORCIDConnect your ORCID iD *help
Researcher Number 10980451
Affiliation (Current) 2026: 滋賀医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2026: 滋賀医科大学, 医学部, 助教
2023 – 2024: 滋賀医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / 0803:Pathology, infection/immunology, and related fields
Keywords
Principal Investigator
JAK / ATP競合阻害薬 / ケミカルバイオロジー / 低分子化合物 / JAK2-V617F / 逆説的活性化 / 阻害薬中断症候群 / ATP競合的阻害薬 / JAK阻害薬 / JAK-STAT … More / 副作用 / シグナル伝達 / paradox / キナーゼ / 阻害薬 / アロステリック効果 Less
  • Research Projects

    (2 results)
  • Research Products

    (1 results)
  •  JAK阻害薬中止症候群の根源的メカニズム解明Principal Investigator

    • Principal Investigator
      樋口 牧郎
    • Project Period (FY)
      2026 – 2027
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Shiga University of Medical Science
  •  Analysis of paradoxical activation of JAK1 by JAK inhibitors and its effect on the immune systemPrincipal Investigator

    • Principal Investigator
      Higuchi Makio
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0803:Pathology, infection/immunology, and related fields
    • Research Institution
      Shiga University of Medical Science

All 2025

All Presentation

  • [Presentation] JAK阻害薬は活性型JAK変異体を逆説的に活性化させる2025

    • Author(s)
      樋口牧郎、平田多佳子
    • Organizer
      日本ケミカルバイオロジー学会第19回年会
    • Data Source
      KAKENHI-PROJECT-23K19480

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