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TAKAHATA Naohiko  高畑 直彦

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高畑 直彦

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Researcher Number 20000987
External Links
Affiliation (based on the past Project Information) *help 1988 – 1996: 札幌医科大学, 医学部, 教授
1986: 札幌医科大学, 医学部, 教授
Review Section/Research Field
Principal Investigator
Psychiatric science
Except Principal Investigator
Psychiatric science / Public health/Health science
Keywords
Principal Investigator
amyloid beta protein / amyloid precursor protein / アミロイドβ蛋白 / アミロイド前駆体蛋白 / アルツハイマー病 / clathrin / proteolytic processing / transferrin receptor / リソソーム経路 / lysosomal pathway … More / ライソゾーム系輸送経路 / cultured myocyte / beta-COP chloroquine / vesicular transport / Alzheimer病 / β-cop / adaptor protein / クラスリン / 細胞内輸送経路 / リソソーム系関連経路 / Concanamycin A / β-COP / 輸送小胞 / rab 7 / chloroquine / lysosome pathway / beta蛋白 / 熱ショック / 細胞内処理過程 / ライソゾーム経路 / 細胞内輸送システム / モノクローナル抗体 / rab7 / クロロキン / endosomal / leupeptin / cell culture / processing / monoclonal antibody / Alzheimer's disease / β蛋白 / membrane bound APP / soluble APP / アルツハイマ-病 / 血小板 / アミロイド / ロイペプチン / 培養細胞 / モノクロナール抗体 … More
Except Principal Investigator
amyloid precursor protein / amyloid beta protein / アミロイドβ蛋白 / アミロイド前駆体蛋白 / アルツハイマー病 / Alzheimer's disease / monoclonal antibody / PHF / in vitro / 細胞内処理過程 / アミロイド / SP-40,40 / モノクローナル抗体 / Amyloid / NFT / acidic compartment / chloroquine / myocyte / proteolytic processing / Alzheimer's disease model / APP / Alzheimer病 / リソソーム経路 / エンドソーム / 培養細胞系 / 培養筋細胞 / クロロキン / rab7 / アルツハイマー病モデル / endoplasmic reticulum / Golgi apparatus / transfection / brefeldin A / monensin / trafficking / レーザー顕微鏡 / 細胞内輸送経路 / beta蛋白 / 細胞内輸送システム / 遺伝子導入 / BrefeldinA / Monensin / ERGIC53 / galactosyltransferase / 細胞内輸送 / amyloid associated proteins / apoE / amyloid deposition / βーprotein / βー蛋白 / モノクロ-ナル抗体 / 35kDa蛋白 / serum protein 40ー40 / Bー蛋白 / アルツハイマ-病 / アミロイド関連蛋白 / アポリポプロテインE / 神経原線維変化 / B-protein / neurofilament / Ubiquitin / tau / microtubules-associated proteins / monoclonal antibodies / substructure / ultrastructure / negative staining / diffraction / computerized digital processing / PD-complex / Alzheimer disease / 誘発電位 重心動揺度 / 振戦 / CT / MRI / 協調機能 / 認知機能 / 運動機能 / 水銀鉱山退職者 Less
  • Research Projects

    (9 results)
  • Co-Researchers

    (6 People)
  •  高齢化した元水銀鉱山退職者・マンガン精錬工程従事者の神経・精神機能とADL…加齢と重金属暴露の複合影響に関する追跡的研究

    • Principal Investigator
      岸 玲子
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Public health/Health science
    • Research Institution
      Sapporo Medical University
  •  Novel Experimental Model in vitro for Amyloid beta Production and Molecular Biological Analysis of Amyloidogenesis

    • Principal Investigator
      FUKATSU Ryo
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Psychiatric science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  An Attempt to Identify Amyloid Precursor Protein Processing Pathway Involving Lysosomal System by Vesicle Specific ProteinPrincipal Investigator

    • Principal Investigator
      TAKAHATA Naohiko
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  Molecular Biological Studies on Processing of Amyloid Precursor Protein in Lysosomal PathwayPrincipal Investigator

    • Principal Investigator
      TAKAHATA Naohiko
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  Molecular Biological Studies on Trafficking and Processing of Amyloid Precursor Protein

    • Principal Investigator
      FUKATSU Ryo
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Psychiatric science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  MOLECULAR BIOLOGICAL STUDIES OF APP PROCESSINGPrincipal Investigator

    • Principal Investigator
      TAKAHATA Naohiko
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  MONOCLONAL ANTIBODIES RAISED AGAINST SENILE PLAQUES AND NEUROFIBRILLARY TANGLES IN ALZHEIMER'S DISEASE

    • Principal Investigator
      FUKATSU Ryo
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Psychiatric science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  モノクローナル抗体によるアルツハアマー病特異蛋白に関する研究

    • Principal Investigator
      深津 亮
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Sapporo Medical University
  •  デジタル画像処理法を用いた神経原線維変化の立体構造に関する研究

    • Principal Investigator
      FUKATSU Ryo
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Sapporo Medical University
  • 1.  FUKATSU Ryo (10113614)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  FUJII Mitsuru (80199299)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  岸 玲子 (80112449)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  佐藤 剛 (00162446)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  三宅 浩次 (20045363)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  相沢 裕二 (60202446)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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