KATO Yuzo 加藤有三

Researcher Number	20014128
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2005 – 2006: 長崎大学, 大学院医歯薬学総合研究科, 教授 2002 – 2005: 長崎大学, 大学院・医歯薬学総合研究科, 教授 1987 – 2001: 長崎大学, 歯学部, 教授
Review Section/Research Field	Principal Investigator Functional basic dentistry / Functional basic dentistry Except Principal Investigator Functional basic dentistry / Functional basic dentistry / 病態科学系歯学(含放射線系歯学)
Keywords	Principal Investigator osteoclast / カテプシンD / カテプシンE / カテプシンB / カテプシンH / メダラシン / Arg-gingipain / cysteine proteinase / Lys-gingipain / periodontal disease … More / Porphyromonas gingivalis / transport / 破骨細胞 / ODF / プロセッシング / メタロプロテアーゼ / Glycolipid / Metalloprotease / Osteoclast / Osteoprotegerin (OPG) / RANKL / Shedding / aspartic proteinase / atopic disease / cathepsin E / signal transduction / Knockout mouse / リソゾ-ム性酵素 / 細胞内プロテア-ゼ / プロテア-ゼ / エナメル芽細胞 / ディフィレッシャルディスプレー / PCR / mRNA / ディフィレンシャルディスプレー / Sec / periodonatal disease / periodontitis disease / ラット / オステオカルシン / イオン化カルシウム / 低カルシウム血症 / エーテル麻酔 / 血清中イオン化Ca / 血漿中イオン化Ca / ストレス / Rat / Osteocalcin / Ionized calcium / Hypocalcemia / Ether anesthesia / シェディング(shedding) / 破骨細胞分化因子(ODF) / オステオプロテグリン(OPG) / メタロプロテアーゼ-ディスインテグリン / プロテアーゼ / 融合 / PCR. / 遺伝子 / shedding / osteoclast differentiation factor (ODF) / osteoprotegerin (OPG) / metalloprotease-disintegrins / D-PDMP / Processing enzyme / ODF(RANKL) / プロセッシング酵素 / OPG / ADAM / _D-PDMP / Processing Enzyme / knockout mouse / atonic disease / knockout mice / リソゾーム性酵素 / カテプシンL / リソゾーム酵素 / 抗炎症剤 / Lysosomal proteinases / Cathepsin B / Cathepsin H / Cathepsin D / Cathepsin E … More Except Principal Investigator 破骨細胞 / Arg-gingipain / cysteine proteinase / Lys-gingipain / transport / periodontitis disease / RANKL / M-CSF / TRAP / 脂質ラフト / OSTEOCLAST / LIPID RAFT / Porphyromonas gingivalis / periodontal disease / Porphysomonas gingivalis / LPS / GM1 / 歯周病 / サイトカイン / TNF / TNF受容体 / IL-1 / ノックアウトマウス / 唾液 / ラクトフェリン / 抗菌作用 / 歯槽骨吸収 / 骨吸収 / 概日リズム / 骨芽細胞 / 局所的骨吸収因子 / オステオポンチン / オステオカルシン / 概口リズム / 骨吸収病態モデル / bisphosphonate / カテプシンD / 扁平上皮癌株細胞 / 病態モデル / 細胞内プロテア-ゼ / 骨吸収促進物質 / 組織再生法 / Alveolar Bone Resorption / Bone Resorption / Circadian rhythm / Osteoclast / Osteoblast / Bone Resorption Factor / Osteopontin / Osteocalcin / タンパク質 / クオリティーコントロール / 糖鎖 / カテプシンE / ツニカマイシン / プロテアソーム / 細胞内蛋白質輸送 / 小胞体 / カテプシン / protein / quality control / oligosaccharide side chain / cathepsin E / tunicamycin / proteasome / カスパーゼ / アポトーシス / 蛍光基質 / 一酸化チッ素(NO) / MNA / プロテアーゼ / caspase / apoptosis / fluorescence substrate / nitric oxide (NO) / osteoclast / アネキシン / ANNEXIN / スフィンゴ糖脂質 / TLR4 / GLYCOSPHINGOLIPID / periodntitis disease / Peophyromonas gingivalis Less

Study of membrane transport system in proteinase produced from Porphyromonas gingivalis
- Principal Investigator
  
  OKAMOTO Kuniaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
歯周病原性細菌におけるタンパク質の新規膜透過システムの解明Principal Investigator
- Principal Investigator
  
  加藤有三
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
FUNCTIONAL REGULATION OF OSTEOCLAST BY GLYCOSPHINGOLIPID
- Principal Investigator
  
  SAKAI Eiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  NAGASAKI UNIVERSITY
Study of the correlation bone in osteoclast resorption with atopic diseasePrincipal Investigator
- Principal Investigator
  
  KATO Yuzo
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  NAGASAKI UNIVERSITY
Establishment of protein expression system in Porphyromonasi gingivalis
- Principal Investigator
  
  OKAMOTO Kuniaki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  NAGASAKI UNIVERSITY
歯周病原性細菌における新規の膜結合型タンパク質の遺伝学的探求とその精製の試みPrincipal Investigator
- Principal Investigator
  
  加藤有三
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
FUNCTION OF ANNEXIN FAMILY PROTEINS IN OSTEOCLAST DIFFERENTIATION AND ACTIVATION
- Principal Investigator
  
  SAKAI Eiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
炎症性サイトカイン関連遺伝子変異マウスを用いて歯周組織破壊と再生の機序を解析する
- Principal Investigator
  
  山口朗
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nagasaki University
Design and application of new fluoroescent substrate against membrane-bound processing enzymePrincipal Investigator
- Principal Investigator
  
  KATO Yuzo
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  NAGASAKI UNIVERSITY
A novel method for fluorescence microscopic demonstration of caspase activity
- Principal Investigator
  
  SAKAI Hideaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University School of Dentistry
Roles of metalloprotease-disintegrins in osteoclastogenesisPrincipal Investigator
- Principal Investigator
  
  KATO Yuzo
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University School of Dentistry
エナメル芽細胞におけるRNAフィンガーブリンティングPrincipal Investigator
- Principal Investigator
  
  加藤有三
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
Quality control mechanism for secretory proteins in intracellular protein sorting pathway
- Principal Investigator
  
  SAKAI Hideaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
Role of osteocalcin in the calcium metabolism disorderPrincipal Investigator
- Principal Investigator
  
  KATO Yuzo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
Studies of the Etiology and Therapeutic Approach of Alveolar Bone Resorption
- Principal Investigator
  
  OGURA Hideaki
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Medical and Dental University
硬組織に由来する細胞の機能発現とリソゾ-ム性酵素の役割に関する実験薬理学的研究Principal Investigator
- Principal Investigator
  
  加藤有三
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
唾液内ラクトフェリンの抗菌機序と歯科疾患適用への基礎的研究
- Principal Investigator
  
  山本健二
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
Roles of lysosomal proteinases in the patho-physiological changes of hard tissues.Principal Investigator
- Principal Investigator
  
  KATO Yuzo
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University

All 2006 2005 2004

All Journal Article

[Journal Article] Pepstatin A, an aspartic proteinase inhibitor, suppresses RANKL-induced osteoclast differentiation.2006
- Author(s)
  Yoshida H., Okamoto K., Iwamoto T., Sakai E., Kanaoka K., Hu JP., Shibata M., Hotokezaka H, Nishishita K., Mizuno A., Kato Y.
- Journal Title
  
  J.Biochem. 139
  
  Pages: 583-590
- NAID
  10018847122
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591942
[Journal Article] Taste cell responses in the frog are modulated by parasympathetic efferent nerve fibers.2005
- Author(s)
  Sato T., Nishishita K., Kato Y., et al.
- Journal Title
  
  Chem.Sences 30
  
  Pages: 761-769
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390563
[Journal Article] Laminin □2 Is Essential for Odontoblast Differentiation Regulation Dentin Siaroprotein Expression.2004
- Author(s)
  Yuasa K, Fukumoto S, Kamasaki Y, Yamada A, Fukumoto E, Kanaoka K, Saito K, Harada H, Arikawa-Hirasawa E, Miyagoe-Suzuki Y, Takeda S, Okamoto K, Kato Y, Fujiwara T.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 10286-10292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591971

1. SAKAI Eiko (10176612)

# of Collaborated Projects: 10 results

# of Collaborated Products: 1 results
2. OKAMOTO Kuniaki (10311846)

# of Collaborated Projects: 7 results

# of Collaborated Products: 2 results
3. SAKAI Hideaki (40225769)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. SHIBATA Mitsue (20274665)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
5. NISHISHITA Kazuhisa (20237697)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
6. OZAKI Miho (50191341)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. YAMAMOTO Kenji (40091326)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. KOBAYASHI Yashuhiro (20264252)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NAKAYAMA Koji (80150473)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. AWAYA Akira

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. OGURA Hideaki (20013831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MUROTA Sei-itsu (50072989)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MATSUMOTO Akira (40064365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SUDA Tatsuo (90014034)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. ENOMOTO Shoji (40013940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MATAKI Shiro (80157221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MATSUDA Naoki (00304973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. FUKUMOTO Satoshi (30264253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 朔敬 (40145264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 山口朗 (00142430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 柴田恭明 (80253673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 藤田修一 (00181355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 原宜興 (60159100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 高橋弘 (20124597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 高木浩司 (40244074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KATO Yuzo 加藤 有三

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Co-Researchers

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歯周病原性細菌におけるタンパク質の新規膜透過システムの解明Principal Investigator

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Study of the correlation bone in osteoclast resorption with atopic diseasePrincipal Investigator

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Principal Investigator

Project Period (FY)

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Research Institution

歯周病原性細菌における新規の膜結合型タンパク質の遺伝学的探求とその精製の試みPrincipal Investigator

Principal Investigator

Project Period (FY)

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Principal Investigator

Project Period (FY)

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Principal Investigator

Project Period (FY)

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Design and application of new fluoroescent substrate against membrane-bound processing enzymePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of metalloprotease-disintegrins in osteoclastogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

エナメル芽細胞におけるRNAフィンガーブリンティングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Research Institution

Role of osteocalcin in the calcium metabolism disorderPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

KATO Yuzo 加藤有三