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ISHII Hiromasa  石井 裕正

ORCIDConnect your ORCID iD *help
Researcher Number 20051500
Other IDs
Affiliation (based on the past Project Information) *help 1994 – 2003: Keio University, Dept of Internal Medicine, Professor, 医学部, 教授
1997: Keio University, School of Medicine, Professor, 医学部, 教授
1993: 慶應義塾大学, 医学部消化器内科, 助教授
1990 – 1992: 慶応義塾大学, 医学部, 助教授
1991: KEIO UNIVERSITY SCHOOL OF MEDICINE, ASSOCIATE PROFESSOR, 医学部, 助教授 … More
1990: 慶應義塾大学, 医学部・消化器内科, 助教授
1988: Keio University, School of Medicine, 医学部・内科, 助教授
1987: 慶応大学, 医学部内科, 助教授 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Biomedical engineering/Biological material science
Except Principal Investigator
Gastroenterology / Gastroenterology
Keywords
Principal Investigator
NO / 幹細胞 / アポトーシス / NF-kB / エンドトキシン / Endotoxin / nitric oxide / hepatic differentiation induction method / collagen gel sandwich configuration / stem cell autotransplantation … More / side population cell / コラーゲンゲル / 初代培養肝細胞 / 肝不全 / 肝硬変 / 移植医療 / 細胞融合 / 肝再生 / 自家細胞移植 / 脾臓 / 肝細胞分化 / 肝細胞分化誘導法 / コラーゲンゲルサインドイッチ法 / 幹細胞自家移植療法 / SP細胞 / Microfabrication / Ito cell / Hepatocyte / Apoptosis / Stem cell / Matrix / Mixed culture / Artificial Liver Support / ステムセル / アルブミン / マイクロファブレケーション / マイクロファブリケーション / 細胞移植 / マトリックス / 伊東細胞 / 肝細胞 / 人工肝 / Alcohol / TNF-alpha / Mitochondrion / Sinusoidal cells / Kupffer cells / NF-κB / カルシウム / 接着因子 / 肝疾患 / TNFα / Kupffer細胞 / ミトコンドリア / アセトアルデヒド / 酸化ストレス / 類洞壁細胞 / Kupffer 細胞 / alcohol / endotoxin / prostagrandin / liver injury / oxidative stress / microcirculatory disturbance / ブロスタグランディン / アルコール / プロスタグランデイン / 肝障害 / 酸素ストレス / 微小循環障害 / Digital image process / Xanthine oxidase / Nitric oxide / Ischemic damage / Carbon tetrachloride / Hepatic microcirculation / Oxidative stress / redox state / NADH自家蛍光 / デジタル画像解析 / キサンチン酸化酵素 / 内毒素 / 虚血障害 / 四塩化炭素 / 肝微小循環 / 活性酸素 … More
Except Principal Investigator
IL-7 / HIV / Brazil / Hepatitis B virus / Human T-cell leukemia virus / Cancer incidence / Cancer mortality / Japanese immigrants / ボリビア / ブラジル / B型肝炎ウィルス / 成人T細胞白血病ウィルス / がん罹患率 / がん死亡率 / 日系移民 / transdifferentiation / Splenic side population / Auto-stem cell transplantation / 肝不全 / 肝硬変 / 移植医療 / 細胞融合 / GFPトランスジェニックラット / 自家細胞移植 / 肝再生 / 幹細胞移植 / 肝臓 / 脾臓 / SP細胞 / 分化転換 / 脾臓SP細胞 / 自己幹細胞移植 / Rho GTPase / Metastasis / Cancer / 大腸癌 / 細胞運動 / Rac / Rho ファミリー蛋白質 / small G protein / RhoファミリーG蛋白 / 転移 / 癌 / Cholera toxin / cytotoxic Tlymphcyte / transgenic mouse / mucosal immunology / oral Immunization / AIDS / SIV / コレラトキシン / 細胞障害性T細胞 / トランスジェニックマウス / 腸管免疫 / 経口免疫 / エイズ / Pathogenesis / Genetic factor / Hepatitis C virus / prognosis / Course / Diagnostic criteria / Hepatocellular carcinoma / Alcoholic cirrhosis / Alcoholic liver disease / 遺伝子型 / アルデヒド脱水素酵素(ALDH)2 / HCVーRNA / C型肝炎ウイルス(HCV) / 肝癌 / アルコ-ル性肝硬変 / 大酒家慢性肝炎 / アルコ-ル性肝障害 / 発生要因 / 遺伝的素因 / C型肝炎ウィルス / 経過・予後 / 診断基準 / 大酒家肝癌 / アルコール性肝硬変 / アルコール性肝障害 Less
  • Research Projects

    (11 results)
  • Co-Researchers

    (40 People)
  •  Splenic SP-cells offer the potential of autologous cell therapy aimed at liver regeneration.

    • Principal Investigator
      KATO Shinzo, 東 俊文
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Experimental research for treatment of liver failure with hepatic tissue stem cell (SP cell)Principal Investigator

    • Principal Investigator
      HORIE Yoshinori, 石井 裕正
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  The essential role of Rho family G protein in tumor metastasis and invasion.

    • Principal Investigator
      AZUMA Toshifumi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Inventory of Artificial Liver Support based on the mixed culture system of Hepatocytes with Ito cellsPrincipal Investigator

    • Principal Investigator
      ISHII Hiromasa
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Keio University
  •  Molecularbiological study for the role of sinusoidal cells in pathogenesis of liver disease.Principal Investigator

    • Principal Investigator
      ISHII Hiromasa
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Induction of cytotoxic Tlymphocyters in the intestinal mucosa by oral immunization of SIV gag or env peptide conjugated with chorela toxin

    • Principal Investigator
      HIBI Toshifumi, 渡辺 守
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Role of oxidative stress and microcirculatory disturbances in the liver injury.Principal Investigator

    • Principal Investigator
      ISHII Hiromasa
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Studies on the pathogenesis and pathophysiology of alcoholic liver cirrhosis and cancer.

    • Principal Investigator
      TAKADA Akira
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Gastroenterology
    • Research Institution
      KANAZAWA MEDICAL UNIVERSITY
  •  ROLE OF OXIDATIVE STRESS IN THE MECHANISM OF HEPATIC DAMAGEPrincipal Investigator

    • Principal Investigator
      ISHII Hiromasa
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      KEIO UNIVERSITY
  •  南米在住日系人のがん罹患の実態とその要因に関する疫学的研究

    • Principal Investigator
      WATANABE Shaw
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Overseas Scientific Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  Cancer and their etiological factors among Japanese in South America

    • Principal Investigator
      WATANABE Shaw
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Overseas Scientific Research
    • Research Institution
      National Cancer Center
  • 1.  KATO Shinzo (30177448)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  AZUMA Toshifumi (00222612)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  HORIE Yoshie (70229227)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  SUEMATSU Makoto (00206385)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  OKANO Hideyuki (60160694)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  HIBI Toshifumi (50129623)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  INOKUCHI Sayaka (00383711)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  WATANABE Shaw (60051637)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  TSUGANE Shoichiro (40179982)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  MIWA Masanao (20012750)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  渡辺 守 (10175127)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  RUY Laurenti
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  TAKADA Akira (30064497)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TANIKAWA Kyuichi (10080649)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TSUJII Tadasu (30075064)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  OHTA Yasuyuki (40033055)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  OKUDAIRA Masahiko (50050331)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  HAMAMATSU Hisayoshi (00208597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  MORIYA Susumu (10220089)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  YOKOYAMA Akira (50200910)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  AISO Sadakazu (60138013)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  KUROSE Iwao (50234604)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  YOKOYAMA Hirokazu (70200920)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  MIURA Soichiro (50138012)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  SUZUKI Hidekazu (70255454)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  NISHIDA Jiro (50198470)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  SAITO Hidetsugu (80186949)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  TOMITA Kengo (50317129)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  柳沢 徹 (80191154)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  中村 雄二 (80276253)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  赤池 敏宏 (30101207)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  竹縄 忠臣 (40101315)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  JUAN Seiyu T
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  AUGUSTO Hasi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  JOSE Maria P
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  SABINA LD Go
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  ANTONIO P Mi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  ANTONIO Mirr
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  LAURENTI Ruy
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  MIRRA Antonio
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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