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Yoshizato Katsutoshi  吉里 勝利

ORCIDConnect your ORCID iD *help
… Alternative Names

YOSHIZATO KATSUTOSHI  吉里 勝利

吉里 勝利  ヨシザト カツトシ

YOSHIZATO Katsutoshi  吉里 勝利

YOSHIZATO Katutoshi  吉里 勝利

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Researcher Number 20095516
Other IDs
External Links
Affiliation (Current) 2025: 大阪公立大学, 大学院医学研究科, 特任教授
2025: 自治医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help 2022 – 2023: 自治医科大学, 医学部, 客員教授
2020: 自治医科大学, 医学部, 客員教授
2015: 大阪市立大学, 大学院医学研究科, 客員教授
2013: 大阪市立大学, 医学(系)研究科(研究院), 教授
2013: 大阪市立大学, 医学研究院, 教授 … More
2011 – 2012: 大阪市立大学, 医学(系)研究科(研究院), 客員教授
2005 – 2007: 広島大学, 理学部, 教授
2006: Hiroshima University, Graduate School of Science, Professor, 大学院理学研究科, 教授
2003 – 2005: 広島大学, 大学院・理学研究科, 教授
2003: 広島大学, 大学院・病理学研究科, 教授
2001 – 2002: 広島大学, 理学研究科, 教授
2001: Hiroshima Univ., Graduate School of Science, Professor, 大学院・理学系研究科, 教授
2000 – 2001: 広島大学, 大学院・理学研究科, 教授
1995 – 1999: 広島大学, 理学部, 教授
1990 – 1993: Hiroshima Univ., Fac. Sci., Professor, 理学部, 教授
1988 – 1989: 東京都立大学, 理学部, 助教授
1986: Dept.of Plastic Surgery,Kitasato Univ. School of Med., 医学部, 助教授
1986: School of Medicine, Kitasato University, 医学部, 助教授
1985: 北里大学, 医, 助教授 Less
Review Section/Research Field
Principal Investigator
生物形態・構造 / 広領域 / Basic Section 52040:Radiological sciences-related / Basic Section 56070:Plastic and reconstructive surgery-related / Morphology/Structure / Biomedical engineering/Biological material science / 内科学一般 / 動物発生・生理学 / Developmental biology
Except Principal Investigator
Digestive surgery … More / 遺伝学 / Biological Sciences / General anatomy (including Histology/Embryology) / 有機工業化学 / Embryonic/Neonatal medicine / Gastroenterology / Medical pharmacy / Obstetrics and gynecology / 動物発生・生理学 / General surgery Less
Keywords
Principal Investigator
変態 / コラーゲン / Collagen / ウニ / 甲状腺ホルモン / アフリカツメガエル / Fibroblasts / 線維芽細胞 / コラ-ゲン / 両生類 … More / 遺伝子クローニング / カエル / カイメン / コラゲナーゼ / ケラチン / 予防治療 / 幹細胞移植 / 慢性放射線障害 / 脂肪組織由来幹細胞 / 再生医療 / 難治性潰瘍 / マトリックス微小細片 / ヒト脂肪組織 / 微小細片化組織 / Hepatocytes / Artificial Liver / 酸素分圧 / 細胞組込み型人工臓器 / 細胞培養 / 肝細胞 / 人工肝臓 / transgenesis / tissue remodeling / thyroid hormone response element / mircro array / skin / Hox genes / thyroid hormone / metamorphosis / トランスジェニック / 無尾両生類 / TRE / 甲状腺ホルモン応答配列(TRE) / 遺伝子ネットワーク / 甲状腺ホルモン応答配列 / マイクロアレイ / 甲状腺ホルモン応答遺伝子 / トランスジェニックカエル / sustained release / chimeric protein / cytokine / drug delivery / interleukin 2 / collagen / バキュロウイルス発現系 / IL-2 / バイオマテリアル / キメラ分子 / バキュロウィルス / bFGF / IL2 / 固相化 / インタロイキン2 / EGF / 融合(キメラ)タンパク質 / 徐放システム / キメラタンパク質 / サイトカイン / ドラックデリバリー / インターロイチン2 / COLLAGEN / KERATIN / SKIN METAMORPHOSIS / THYROID HORMONE / NEWT / AFRICAN CLAWED FROG / BULLFROG / ANURA AMPHIBIA / カテプシンD / ホメオボックス遺伝子 / コラゲ-ナーゼ / 両性類 / カテプシン / プロラクチン / アカハライモリ / 再生 / 皮膚変換 / 変態ホルモン / イモリ / ウシガエル / Mesozoans / Sea urchins / Sponges / Collagen genes / 線維茅細胞 / クラゲ / 二胚虫 / コラ-ゲン遺伝子 / Gelatin / Recombinant DNA / Artificial skin / Insulin genes / Diabetes mellitus / 血糖値 / インシュリン / ゼラチン / 遺伝子組換え / 人工皮膚 / インスリン遺伝子 / 糖尿病 / プロテアーゼインヒビター / プロテアーゼ / アクチン / 組織崩壊 / ホルモン / 甲殻類 / 魚類 / ショウジョウバエ / 環境適応戦略 / 酵素化学 / 海産無脊椎動物 / 分子進化 / プラナリア / 無脊椎動物 / ホ乳類 / MMP / 上皮間充織相互作用 / 間充織因子 / 表皮細胞 / 毛乳頭細胞 / 毛母細胞 … More
Except Principal Investigator
アフリカツメガエル / 性決定遺伝子 / サイトグロビン / MRP2 / OATP / BeWo / 人工皮膚 / キメラマウス / プロテオミクス / 二次元電気泳動 / 蛋白質 / プロテオーム / アルツハイマー病 / 固相法 / 性決定 / 肝臓基質 / iPS細胞 / 肝星細胞 / 肝細胞 / Coculture system / a prolonged Survival of hepatocytes / Cell-Cell Interaction / 肝細胞と非肝細胞の相互作用 / 混合培養 / 可溶性因子 / 細胞-細胞相互作用 / 混合培養法 / 初代培養肝細胞 / Burn treatment / Poly-L-leucine / Poly(amino acid) / Wound dressing / Artificial skin / 組織適合性 / フィブリン / 医用材料 / 生体適合性材料 / 生体適合性 / 熱傷治療 / ポリ-L-ロイシン / ポリアミノ酸 / 創傷被覆材 / head organizer genes / in vitro fertilization / molecular embryogenesis / neural tube disclosure / anencephaly / transgenic forg / heme-protein / cytoglobin / 頭部形成遺伝子 / 体外受精 / 分子発生学 / 神経管閉鎖不全 / 無脳症 / トランスジェニックガエル / ヘムタンパク質 / vitamin A / myofibroblast / oxygen / heme / globin / liver fibrosis / stellate cell / 抗ペプチド / HLA-DR / 炎症性腸疾患 / 臓器線維化 / 星細胞 / ビタミンA貯蔵細胞 / ヘモグロビン / chimeric mice / human hepatocyte / liver uptake / organic anions / biliary excretion / liver transport / ヒト肝細胞 / 肝取り込み / 有機アニオン / 胆汁排泄 / 肝輸送 / three-dimensional culture / spheroid / decidual cells / endometrial cells / implantation / 3次元培養 / スフェロイド / 脱落膜化 / 子宮内膜細胞 / 着床 / Metamorphosis / Sex determination mechanism / Xenopus laevis / Gene mapping / Chromosome map / Chromosome / 変態 / 性決定機構 / 遺伝子マッピング / 染色体地図 / 染色体 / 器官再構築 / 新しい生理機能 / 細胞組み込型人工臓器 / 臓器工学 / 発生生物学 / 器官形成 / 線維芽細胞 / 表皮細胞 / 培養皮膚 / 皮膚移植 / コラーゲン / 皮膚 / 肝障害 / 組織修復 / 肝再生 / 脂肪肝の脆弱性 / cytokeratin 18 fragment / 細胞死 / 術後肝障害 / 脂肪性肝炎 / Taxol / Takigawa胃癌細胞株 / 抗癌剤感受性試験 / 転移性肝癌 / SCIDマウス / uPA / 抗癌剤 / 薬剤感受性 / uPA/SCIDマウス / AFP産生胃癌 / 肝転移モデル / プレセニリン / 質量分析 / 神経変性疾患 / 痴呆 / 脳神経疾患 / ゲノム解析 / クローニング / クロ-ニング Less
  • Research Projects

    (28 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (57 People)
  •  培養間葉系幹細胞の全身投与による確定的放射線障害の画期的予防治療法の開発Principal Investigator

    • Principal Investigator
      吉里 勝利
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Jichi Medical University
  •  Optimization, Characterization and Regenerative Medicine Application of Human Micronized Cellular Adipose MatrixPrincipal Investigator

    • Principal Investigator
      YOSHIZATO KATSUTOSHI
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Jichi Medical University
  •  Reconstitution of human hepatic cells in decellularized rodent liver

    • Principal Investigator
      IKEDA Kazuo
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka City University
  •  The ability of tisuue repair and regeneration in steatohepatitic liver

    • Principal Investigator
      KAMOHARA Yukio
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  ヒト肝細胞で構築された肝臓をもつキメラマウスを利用した抗癌剤感受性試験

    • Principal Investigator
      谷口 堅
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Nagasaki University
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  Molecular Mechanism for Anencephaly

    • Principal Investigator
      OBARA Masanobu
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Functional analysis of cytoglobin that is expressed and induced in liver cirrhosis

    • Principal Investigator
      KAWADA Norifumi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka City University
  •  Mechanism of Region-dependent Metamorphic Tissue RemodelingPrincipal Investigator

    • Principal Investigator
      YOSHIZATO Katsutoshi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphology/Structure
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Estimation of transport activities in human hepatocyte : analysis using mice with humanized liver

    • Principal Investigator
      SUZUKI Hiroshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      The University of Tokyo
  •  プロテオームによるアルツハイマー病の病態解析法の開発

    • Principal Investigator
      下濱 俊
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  プロテオームによるアルツハイマー病の病態解析法の開発

    • Principal Investigator
      下濱 俊
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Production of functional climeric collagensPrincipal Investigator

    • Principal Investigator
      YOSHIZATO Katsutoshi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Hiroshima University
  •  変態による動物の環境適応戦略機構に関する研究Principal Investigator

    • Principal Investigator
      吉里 勝利
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      生物形態・構造
    • Research Institution
      Hiroshima University
  •  コラーゲンとコラーゲナーゼ遺伝子の比較生物学的研究Principal Investigator

    • Principal Investigator
      吉里 勝利
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      生物形態・構造
    • Research Institution
      Hiroshima University
  •  Elucidation of mechanism of determination of morphological and structural specificity of amphibiaPrincipal Investigator

    • Principal Investigator
      YOSHIZATO Katsutoshi
    • Project Period (FY)
      1995 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      生物形態・構造
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Three-dimensional culture of human endometrial cells that show decidual changes in response to sex steroid hormone

    • Principal Investigator
      HARA Tetsuaki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Hiroshima University School of Medicine
  •  毛誘導因子の分離精製Principal Investigator

    • Principal Investigator
      吉里 勝利
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Developmental biology
    • Research Institution
      Hiroshima University
  •  アフリカツメガエルの性決定遺伝子の構造解析と性決定機構の解析

    • Principal Investigator
      近藤 壽彦
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      遺伝学
    • Research Institution
      Gunma University
  •  アフリカツメガエルの性決定遺伝子のクロ-ニング

    • Principal Investigator
      KONDO Toshihiko
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      遺伝学
    • Research Institution
      Gunma University
  •  Studies on the origin of body plan of multicellular animalsPrincipal Investigator

    • Principal Investigator
      YOSHIZATO Katsutoshi
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      広領域
    • Research Institution
      Hiroshima University
  •  Development of a new Chromosome-Identification Method and Gene-Mapping of Xenopus Laevis Chromosome.

    • Principal Investigator
      KONDO Toshihiko
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      遺伝学
    • Research Institution
      Gunma University
  •  treatment of diabetes mellitus by cultured skin transfected with insulin genesPrincipal Investigator

    • Principal Investigator
      YOSHIZATO Katutoshi
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      内科学一般
    • Research Institution
      Hiroshima University
      Tokyo Metropolitan University
  •  臓器工学的応用を指向した器官形成の総合的研究

    • Principal Investigator
      水野 丈夫
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      動物発生・生理学
    • Research Institution
      Teikyo University
  •  両棲類に見出された"アクチン分解系"の生理的意義に関する研究Principal Investigator

    • Principal Investigator
      吉里 勝利
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      動物発生・生理学
    • Research Institution
      Kitasato University
  •  人工皮膚の臨床応用に関する研究

    • Principal Investigator
      SHIOYA Nobuyuki
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kitasato University
  •  Analysis of Cell-Cell and Cell-matrix Interactions in a coculture system.

    • Principal Investigator
      YAMAMOTO N.
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      KITASATO UNIVERSITY
  •  Preparation of Biocompatible Poly(amino acid) and Its Copmposite Materials and Their Application to Artificial Skin

    • Principal Investigator
      SENO Manabu
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      有機工業化学
    • Research Institution
      Institute of Industrial Science, University of Tokyo
  •  Development of Artificial Cultured LiverPrincipal Investigator

    • Principal Investigator
      YOSHIZATO Katsutoshi
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      広領域
    • Research Institution
      Kitasato University

All 2015 2012 2006 2005 Other

All Journal Article Book

  • [Book] 再生医療のための発生生物学(浅島誠編集)第3章「組織再構築過程としての無尾両生類の変態」2006

    • Author(s)
      鈴木賢一, 吉里勝利
    • Total Pages
      20
    • Publisher
      コロナ社
    • Data Source
      KAKENHI-PROJECT-15370028
  • [Book] 再生医療のための発生生物学 第3章「組織再構築過程としての無尾両生類の変態」(浅島誠 編集)2005

    • Author(s)
      鈴木賢一, 吉里勝利
    • Total Pages
      20
    • Publisher
      コロナ社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15370028
  • [Journal Article] Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism.2015

    • Author(s)
      Teranishi Y, Matsubara T, Krausz KW, Le TT, Gonzalez FJ, Yoshizato K, Ikeda K, Kawada N
    • Journal Title

      Lab Invest

      Volume: 95 Issue: 5 Pages: 515-524

    • DOI

      10.1038/labinvest.2015.29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670589, KAKENHI-PROJECT-26870501
  • [Journal Article] A novel animal model for in vivo study of liver cancer metastasis2012

    • Author(s)
      Fujiwara S, Fujioka H, Tateno C, Taniguchi K, Ito M, Ohishi H, Utoh R, Ishibashi H, Kanematsu T, Yoshizato K.
    • Journal Title

      World J Gastroenterol

      Volume: 18 Pages: 3875-3882

    • NAID

      120006985572

    • Data Source
      KAKENHI-PROJECT-23592002
  • [Journal Article] Structural characterization of the proximal and distal histidine environment of cytoglobin and neuroglobin.2005

    • Author(s)
      Sawai H, Makino M, Mizutani Y, Ohta T, Sugimoto H, Uno T, Kawada N, Yoshizato K, Kitagawa T, Shirro Y
    • Journal Title

      Biochemistry. 44(40)

      Pages: 13257-13265

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590618
  • [Journal Article] A novel Xenopus laevis larval keratin gene, xlk2 : its gene structure and expression during regeneration and metamorphosis of limb and tail.

    • Author(s)
      I.TazawaK.Simizu-Nishikawa, K.Yoshizato
    • Journal Title

      Biochim. Biophys. Acta. (in press)

    • NAID

      120000878058

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15370028
  • [Journal Article] Molecular cues in the epithelial-mesenchymal interaction required for the body- and tail-dependent metamorphic transformation of anuran larval skin.

    • Author(s)
      K.Yoshizato
    • Journal Title

      Int.Rev.Cyto (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15370028
  • [Journal Article] Molecular cues in the epithelial-mesenchymal interaction required for the body- and tail-dependent metamorphic transformation of anuran larval skin

    • Author(s)
      K.Yoshizato
    • Journal Title

      Int. Rev. Cyto (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15370028
  • [Journal Article] Molecular cues in the epithelial-mesenchymal interaction required for the body and tail-dependent metamorphic transformation of anuran larval skin

    • Author(s)
      K.Yoshizato
    • Journal Title

      Int.Rev.Cyto (in press)

    • Data Source
      KAKENHI-PROJECT-15370028
  • [Journal Article] A novel Xenopus laevis larval keratin gene, xlk2 : its gene structure and expression during regeneration and metamorphosis of limb and tail.

    • Author(s)
      Tazawa, I., Simizu-Nishikawa, K., Yoshizato, K.
    • Journal Title

      Biochim.Biophys.Acta (in press)

    • NAID

      120000878058

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15370028
  • [Journal Article] Gene expression and tissue distribution of cytoglobin an dmyoglobin in the Amphibia and the Reptilia : A possible compensation of myoglobin with cytoglobin in skeletal muscle cells of the Anura that lacks myoglobin gene,

    • Author(s)
      Yang Xi, M Obara, Y Ishida, S Ikeda, K Yoshizato
    • Journal Title

      Gene In press

    • Data Source
      KAKENHI-PROJECT-17591142
  • [Journal Article] Gene expression and tissue distribution of cytoglobin and myoglobin in the Amphibia and the Reptilia : A possible compensation of myoglobin with cytoglobin in skeletal muscle cells of the Anura that lacks myoglobin gene.

    • Author(s)
      Yang Xi, Masanobu Obara, Yuji Ishida, Shino Ikeda, Katsutoshi Yoshizato
    • Journal Title

      Gene (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591142
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