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ISHIGURO Sei  石黒 誠一

ORCIDConnect your ORCID iD *help
Researcher Number 20111271
Other IDs
External Links
Affiliation (based on the past Project Information) *help 1999 – 2004: Hirosaki Univ., Dept. Agri. Life Sci., Prof., 農学生命科学部, 教授
1998: 弘前大学, 農学生命科学部, 助教授
1988 – 1997: School of Medicine, Tohoku University, 医学部, 講師
1990: Tohoku University School of Medicine Assistant Professor, 医学部, 構師
1986 – 1987: 東北大学, 医学部(眼科), 講師
1986: Tohoku University School of Medicine, 医学部, 講師
Review Section/Research Field
Principal Investigator
Ophthalmology
Except Principal Investigator
Ophthalmology / Human genetics / 遺伝学
Keywords
Principal Investigator
視細胞外節 / all-trans-retinol / 11-cis-retinol / cDNA / レチノール脱水素酵素 / Retinal Degeneration / Enzyme-Linked Immunosorbent Assay / Immunohisto chemisrty / Stereospecificity / Purification … More / Retinol Dehydrogenase / Rod Outer Segments / Bovine Retima / 単クロ-ン抗体 / 膜酵素 / 酵素免疫組織化学 / ビタミンA / 視細胞変性症 / 固相酵素免疫測定法 / 免疫組織化学 / 基質立体特異性 / 精製 / レチノ-ル脱水素酵素 / ウシ網膜 / visual cycle / phospholipids / rhodopsin / rod outer segment / isomerization / 視サイクル / リン脂質 / ロドプシン / 異性化 / retinitis pigmentosa / photoreceptor cells / gene / primary structure / retinol dehydrogenase / 視細胞 / 網膜色素変性症 / 光受容細胞 / 遺伝子 / 一次構造 / c2DNA / fluo-3 / 細胞内カルシウム / 網膜スライス / 虚血 … More
Except Principal Investigator
網膜色素変性 / retinitis pigmentosa / 網膜色素上皮細胞 / cDNA / チロシナーゼ / retina / gene transfer / リポソーム / 遺伝子導入 / bFGF / RPE / 視細胞 / 網膜色素上皮移植 / 硝子体手術 / オプシン / 網膜 / TRANSGENIC MOUSE / TYROSINASE / ALBINISM / トランスジェニック・マウス / チロシナ-ゼ / アルビニズム / melanin / gene cloning / gene expression / tyrosinase / mouse / アルビノ / メラニン / クローニング / 遺伝子発現 / マウス / monoclonal antibody / cathepsin D / retinal pigment epithelium / opsin / ELISA / モノクローン抗体 / カテプシンD / calcium antagonist / GCAP2 gene / カルシウム拮抗剤 / アントシアニン / GCAP2遺伝子 / カルシウム拮抗薬 / BCAP2遺伝子 / glaucoma / conjunctiva / electroporation / gene therapy / 緑内障 / 結膜 / エレクトロポレーション / 遺伝子治療 / nilvadipine / RCS rat / RDH5 gene / RDS gene / peripherin / fundus albipuntatus / RP1遺伝子 / RDS / RDS遺伝子 / ペリフェリン / RDH5遺伝子 / ニルバジピン / RCSラット / RDS5遺伝子 / ペリフェリン・RDS遺伝子 / 白点状眼底 / photoreceptor / adaptation / transgenic mice / gene family / phosducin / 視細胞外節 / 網膜電位図 / 明順応 / トランスジェニックマウス / フォスデューシ / 網膜伝図 / ランスジェニックマウス / アイソフォーム / フォスデューシン / liposomes / excitotoxicity / glutamate / growth factors / neurotrophic factors / cytokines / retinal damage / ischemia / 興奮毒 / グルタミン酸 / 細胞増殖因子 / 神経栄養因子 / 生理活性物質 / 虚血性眼底疾患 / 虚血 / Age-related macular degeneration / Cryopreservation / IPE transplantation / IPE / RPE transplantation / MRI / グリシン / ラミニン / 細胞外基質 / 異種移植 / コラーゲンゲル / 凍結保存 / 培養色素上皮細胞 / 細胞凍結保存 / 虹彩色素上皮移植 / 虹彩色素上皮細胞 / 加齢黄斑変性症 / Growth Factor / SV40 Large T / SDS電気泳動 / SV40ラージT抗原遺伝子 / モノクロナール抗体 / 細胞培養 / ミュラー細胞 / 網膜色素上皮 / 増殖因子 / SV40 largeT / Histopatho logical study / Regeneration of retinal pigment epithelium / Experimental damage of retinal pigment epithelium / Sampling of vitreous / Vitreous surgery / Transplantation of retin at pigment epithelial cells / Neovascularization / Age related macular degeneration / 加令黄斑症 / 組織化学 / 新生血管黄斑症 / 病理組織学的検索 / 網膜色素上皮再生 / 実験的網膜色素上皮障害 / 硝子体サンプリング / 網膜色素上皮細胞移植 / 新生血管 / 加令黄斑変性症 / 免疫組織化学 / 固相酵素免疫測定法 / ロドプシン / 分化 / ビタミンA類 / 色素上皮細胞 / ラット / 器官培養 / GCAP2 / サイトカイン / 修飾因子 Less
  • Research Projects

    (17 results)
  • Co-Researchers

    (25 People)
  •  網膜変性のmodifierとしてのサイトカインと光トランスダクション異常の役割

    • Principal Investigator
      NAKAZAWA Mitsuru
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      Hirosaki University
  •  The effect of new medical treatment for hereditary retinal degeneration based on its molecular pathogenesis

    • Principal Investigator
      NAKAZAWA Mitsuru
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Hirosaki University
  •  New Methods of Gene Transfer to the Retina

    • Principal Investigator
      NAKAZAWA Mitsuru
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Hirosaki University
  •  A Study of Molecular Pathogenesis and Treatment of Retinitis Pigmentosa and Allied Diseases

    • Principal Investigator
      NAKAZAWA Mitsuru
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Hirosaki University
  •  Isomerization of retinol in bovine rod outer segmentsPrincipal Investigator

    • Principal Investigator
      ISHIGURO Sei-ichi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      HIROSAKI UNIVERSITY
  •  虚血網膜における細胞内カルシウム濃度の変化Principal Investigator

    • Principal Investigator
      石黒 誠一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Examination of phosducin gene

    • Principal Investigator
      ABE Toshiaki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Treatment of ischemic retinal injury by administration of various cytokines through vitreous cavity.

    • Principal Investigator
      TAMAI Makoto
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Regeneration of pigment cells and basic and clinical study for treatment of age-related macular degeneration

    • Principal Investigator
      TAMAI Makoto
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Analysis of photoreceptor cell-specific retinol dehydrogenase gene in the patient with retinitis pigmentosa.Principal Investigator

    • Principal Investigator
      ISHIGU Sei-ichi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Cloning of Retinal Cells and investigation of growth and in hibitory foctors

    • Principal Investigator
      ITABASHI Ryuzo
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Basic and clinical approach for analysis and treatment of the age related neovascular maculopathy

    • Principal Investigator
      TAMAI Makoto
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Ophthalmology
    • Research Institution
      TOHOKU UNIVERSITY
  •  Purification and Immunohistochemistry of Retinol Dehydrogenase From Bovine Retinal Rod Outer Segments.Principal Investigator

    • Principal Investigator
      ISHIGURO Sei-ichi
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Molecular Genetics of Human Albinism

    • Principal Investigator
      KIKUCHI Hideaki
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Human genetics
    • Research Institution
      Tohoku University
  •  網膜の器官培養におけるオプシン形成:基礎的研究および臨床薬理学への応用

    • Principal Investigator
      TAMAI Makoto
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Basic research of the process of degradation of rhodopsin by the retinal pigment epithelium and the clinical application.

    • Principal Investigator
      HARA Satoshi
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      TOHOKU UNIVERSITY
  •  Expression of tyrosinase gene introduced into the albino mouse embryo.

    • Principal Investigator
      TAKEUCHI Takuji
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      遺伝学
    • Research Institution
      Tohoku University
  • 1.  TAMAI Makoto (90004720)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  OHKURO Hiroshi (30203748)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  NAKAZAWA Mitsuru (80180272)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  YAMADA Takahoko (40191316)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  OHGURO Ikuyo (90305235)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  KATO Kei-ichi (50260435)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  ABE Toshiaki (90191858)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  SUZUKI Yukihiko (40292148)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  HARA Satoshi (60108537)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  TAKEUCHI Takuji (60006426)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  YAMAMOTO Hiroaki (40174809)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  ITABASHI Ryuzo (20193419)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  YUSUF Durlu K (90250787)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  OHKI Kazuo (80115394)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TAKEDA Atushi (70261534)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KIKUCHI Hideaki (60006111)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  野呂 充 (90208405)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  中根 明夫 (30164239)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  水谷 英之 (20271827)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  山口 克宏 (20200610)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  松本 光生 (50250618)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  久保 勝文 (00292160)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  出井 俊雄 (50091773)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  君塚 佳宏
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  荒川 明
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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