UCHINO Makoto 内野誠

Researcher Number	20117336
Affiliation (based on the past Project Information) *help	2012: 元熊本大学, 大学院・生命科学研究部, 教授 2009 – 2010: Kumamoto University, 大学院・生命科学研究部, 教授 2007 – 2008: Kumamoto University, Department of Neurology, Graduate School of Medical Sciences, Professor 2006: 熊本大学, 大学院医学薬学研究部, 教授 2003 – 2004: 熊本大学, 大学院・医学薬学研究部, 教授 … More 2002: Department of Neurology, Kumamoto University Hospital, Professor, 医学部附属病院, 教授 1998 – 2001: KUMAMOTO UNIVERSITY HOSPITAL,NEUROLOGY,PROFESSOR, 医学部・附属病院, 教授 2000: Department of Neurology, Kumamoto University Hospital Professor, 医学部・附属病院・神経内科, 教授 1998: 熊本大学, 医学部附属病院, 教授 1997: 熊本大学, 医学部付属病院, 教授 Less
Review Section/Research Field	Principal Investigator Neurology / Neurology Except Principal Investigator Neurology / Neurology / Neurophysiology and muscle physiology
Keywords	Principal Investigator gene therapy / 遺伝子治療 / dystrophin / helper-dependent / 筋ジストロフィー / attachment receptor / muscular dystrophy / adenovirus vector / mdxマウス / CAR … More / ジストロフィン / ヘルパーウイルス依存型アデノウイルスベクター / アデノウイルスベクター / skeletal muscle / repetitive transduction of therapeutic gene / coxsackie B and adenovirus receptor / Cre / recombinant adenovirus vector / gutless adenovirus / Gene therapy / helper-dependent adenovirus vector / dko mouse / full-length dystrophin / nNOS / sleeping beautv-transoosone system / mdx mouse / Duchenne muscular dystrophy / hleper-dependent adenovirs / Sleeping Beauty transposon / multiple muscle injection / dkoマウス / helper-dependent adenovirus / ヌードmdxマウス / 反復投与 / 接着受容体 / ヘルパー依存性 / RGD / tropism / ジストロフイン / アタッチメントレセプター / ヘルパーウイルス依存型 / loxP system / ヘルパーウイルス依存型アデノウイルス / 遺伝子導入効率 / 反復遺伝子導入 / hCAR / 免疫原性 / 新世代のアデノウイルスベクター / loxPシステム / IoxP system / lentivirus vector / lentivirus / whole-body plethysmography / 改変レンチウイルス / ヘルパー依存アデノウイルス … More Except Principal Investigator Bcl-2 / RT-PCR / protective effect on degeneration of motor neurons / Cre-loxP recombination / gene therapy / retrograde transport / adenoviral vectors / mutant SOD1 transgenic mouse / amyotrophic lateral sclerosis(ALS) / 変異SOD1 transgenic mice / Cre-loxp / 運動ニューロン / Cre-loxP / 遺伝子治療 / 逆行性軸索輸送 / アデノウィルスベクター / 変異SOD1マウス / 筋萎縮性側索硬化症 / IMMUNOHISTOCHEMISTRY / APOPTOSIS RELATED PROTEIN / APOPTOSIS / CYTOCHROME C / MUSCLE PATHOLOGY / MUTANT MITOCHONDRIAL DNA / MITOCHONDRIAL ENCEPHALOMYOPATHY / DNA断片化 / immunohistochemistry / アポトーシス関連蛋白 / アポトーシス / チトクロームC / 筋病理学的特徴 / 変異ミトコンドリアDNA / ミトコンドリア脳筋症 / 血管内治療 / 血行再建 / 脳血流SPECT / 急性期治療 / 脳梗塞 / 血行再建療法 / 神経機能学 / 骨髄間質細胞 / ウイルスベクター / 遺伝子 / 移植・再生医療 / 間葉系幹細胞 / 遺伝子操作 / 細胞治療 / 筋ジストロフィー Less

Development of SPECT-based objective evaluating system for therapeutic effect of acute revascularization therapy
- Principal Investigator
  
  HIRANO Teruyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Oita University
  Kumamoto University
ex vivo gene manipulation of mesenchymal stem cell and application to cell therapy
- Principal Investigator
  
  MAEDA Yasushi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Kumamoto University
Helper-dependent adenovirusvector and modified lentiviral vector mediated delivery of dystrophin for gene therapy of muscular dystrophyPrincipal Investigator
- Principal Investigator
  
  UCHINO Makoto
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kumamoto University
Gene therapy for progressive muscular dystrophy using a new generation adenovirus vector and transposasePrincipal Investigator
- Principal Investigator
  
  UCHINO Makoto
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kumamoto University
Gene therapy for progressive muscular dystrophy using a new generation adenovirus vector (gutless adenovirus)Principal Investigator
- Principal Investigator
  
  UCHIN Makoto
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kumamoto University
Study on the gene therapy using a new generation adenovirus vector (gutless adenovirus)Principal Investigator
- Principal Investigator
  
  UCHINO Makoto
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kumamoto University
BASIC RESEARCH FOR GENE THERAPY OF AMYOTROPHIC LATERAL SCLEROSIS USING ADENOVIRAL VECTORS
- Principal Investigator
  
  MITA Shuji
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  KUMAMOTO UNIVERSITY
Study on the production and purification of a new generation adenovirus vector (gutless adenovirus) and its clinical applicationPrincipal Investigator
- Principal Investigator
  
  UCHINO Makoto
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kumamoto University
APOPTOSIS INDUCED BY CYTOCHROME C IN MITOCHONDRIAL DISEASES
- Principal Investigator
  
  MITA Shuji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  KUMAMOTO UNIVERSITY

All 2012 2011 2010 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

[Book] 最新神経病学(分担:筋肉疾患)2008
- Author(s)
  内野誠
- Total Pages
  66
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-20591003
[Journal Article] Modified ASPECTS for DWI including deep white matter lesions predicts subsequent intra- cranial hemorrhage2012
- Author(s)
  Kawano H, Hirano T, Nakajima M, Inatomi Y, Yonehara T, Uchino M
- Journal Title
  
  J Neurol
  
  Volume: vol.259 Issue: 10 Pages: 2045-2052
- DOI
  10.1007/s00415-012-6446-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590959
[Journal Article] Muscle fiber type-predominant promoter activity in lentiviral-mediated transgenic mouse2011
- Author(s)
  Suga T, Kimura E, Morioka Y, Ikawa M, Li S, Uchino K, Uchida Y, Maeda Y, Chamberlain JS, Uchino M.
- Journal Title
  
  PloS ONE
  
  Volume: (In press)
- NAID
  120006957404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591003
[Journal Article] Rescue from respiratory dysfunction bytransduction of full-length dystrophin to diaphragm via the peritoneal cavity in utrophin/dystrophin double knockout mice.2011
- Author(s)
  Ishizaki M, Maeda Y, Kawano R, Suga T, Uchida Y, Uchida Y, Uchino K, Yamashita S, Kimura E, Uchino M.
- Journal Title
  
  Mol Ther In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591003
[Journal Article] Rescue From Respiratory Dysfunction by transduction of Full-length Dystrophin to Diaphragm via the Peritoneal Cavity in Utrophn/Dystrophin Double Knockout Mice2011
- Author(s)
  Ishizaki M, Maeda Y, Kawano R, Suga T, Uchida Y, Uchino K, Yamashita S, Kimura E, Uchino M
- Journal Title
  
  Molecular Therapy
  
  Volume: 19(7) Pages: 1230-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200013
[Journal Article] Muscle fiber type-predominant promoter activity in lentiviral-mediated transgenic mouse2011
- Author(s)
  Suga T, Kimura E, Morioka Y, Ikawa M, Li S, Uchino K, Uchida Y, Yamashita S, Maeda Y, Chamberlain JS, Uchino M
- Journal Title
  
  PLoS One.
  
  Volume: 6(3)
- NAID
  120006957404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200013
[Journal Article] Packaging and delivery of full-length dystrophin in a lentiviral vector2011
- Author(s)
  Uchino K, kimura E, SugaT, Koide T, Mori A, Uchida Y, Yamashita S, Maeda Y, et al.
- Journal Title
  
  PloS ONE
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591003
[Journal Article] Muscle fiber type-predominant promoter activity in lentiviral-mediated transgenic mouse.2011
- Author(s)
  Suga T, Kimura E, Morioka Y, Ikawa M, Li S, Uchino K, Uchida Y, Maeda Y, Chamberlain JS, Uchino M.
- Journal Title
  
  PloS One in press
- NAID
  120006957404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591003
[Journal Article] Rescue from respiratory dysfunction by transduction of full-length dystrophinto diaphragm via the peritoneal cavity in mouse with muscular dystrophy2011
- Author(s)
  Ishizaki M, Maeda Y, Kawano R, Suga T, Uchida Y, Uchida Y, Uchino K, Yamashita S, Kimura E, Uchino M.
- Journal Title
  
  Mol Ther
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591003
[Journal Article] Mdx respiratory impairment following fibrosis of the diaphragm. Neuromuscul disord2008
- Author(s)
  Ishizaki, M., Suga, T., Kimura, E., Shiota, T., Kawano, R., Uchida, U., Uchino, K., Yamashita, S., Maeda, Y., Uchino, M.
- Journal Title
  
  (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590951
[Journal Article] Transduction of full-length dystrophin to multiple skeletal muscles improves motor performance and lifespan in utrophin/dystrophin double knockout mice2008
- Author(s)
  Kawano R., Ishizaki M, Maeda Y., Uchida Y., Kimura E., Uchino M.
- Journal Title
  
  Mol Ther (in press)
- NAID
  120002468583
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590951
[Journal Article] Transduction of full-length dystrophin to multiple skeletal muscles improves motor performance and lifespan in utrophin/ dystrophin double knockout mice. Mol Ther2008
- Author(s)
  Kawano, R., Ishizaki, M., Maeda, Y., Uchida, Y., Kimura, E., Uchino, M.
- Journal Title
  
  (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590951
[Journal Article] Mdx respiratory impairment following fibrosis of the diaphragm2008
- Author(s)
  Ishizaki M, Suga T, Kimura E, Shiota T, Kawano R, Uchida U, Uchino K, Yamashita S, Maeda Y, Uchino M.
- Journal Title
  
  Neuromuscular disorders (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590951
[Journal Article] Regions downstream from the WW domain of dystrophin are impotant for binding to postsynaptic densities in the brain2008
- Author(s)
  Sakamoto T, Arima T, Ishizaki M, Kawano R, Koide T, Uchida Y, Ymashita S, Kimura E, Hirano T, Maeda Y, Uchino M.
- Journal Title
  
  Neuromuscular disorders (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590951
[Journal Article] Transduction of full-length dystrophin to multiple skeletal muscles improves motor performance and lifespan in utrophin/dystrophin double knockout mice.2008
- Author(s)
  Kawano R., Ishizaki M, Maeda Y., Uchida Y., Kimura E., Uchino M.
- Journal Title
  
  Mol Ther (in press)
- NAID
  120002468583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590951
[Journal Article] Regions Downstream from the WW domain of dystrophin are important for binding to postsynaptic densities in the brain. Neuromuscul Disord2008
- Author(s)
  Sakamoto, T., Arima, T., Ishizaki, M., Kawano, R., Koide, T., Uchida, Y., Yamashita, S., Kimura, E., Hirano, T., Maeda, Y., Uchino, M.
- Journal Title
  
  (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590951
[Journal Article] Myopathy phenotype in transgenic mice expressing mutated PABPN1 as a model of oculopharyngeal muscular dystrophy.2004
- Author(s)
  Hino H., Araki K., Uyama E., Takeya M., Araki M., Yoshinobu K., Miike K., Kawazoe Y., Maeda Y., Uchino M., Yamamura K.
- Journal Title
  
  Hum.Mol.Genet. 13
  
  Pages: 181-190
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590897
[Journal Article] Targeted conversion of the transthyretin gene in vitro and in vivo.2004
- Author(s)
  Nakamura M., Ando Y., Nagahara S., Sano A., Ochiya T., Maeda S., Kawaji T., Ogawa M., Hirata A., Terazaki H., Haraoka K., Tanihara H., Ueda M., Uchino M., Yamamura K., Yamashita T.
- Journal Title
  
  Gene Therapy 11
  
  Pages: 838-846
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590897
[Journal Article] Myopathy phenotype in transgenic mice expressing mutated PABPN1 as a model of oculopharyngeal muscular dystrophy2004
- Author(s)
  Hino H., Araki K., Uyama E., Takeya M., Araki M., Yoshinobu K., Miike K., Kawazoe Y., Maeda Y., Uchino M., Yamamura K.
- Journal Title
  
  Hum.Mol.Genet. 13
  
  Pages: 181-190
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590897
[Journal Article] Effective repetitive dystrophin gene transfer into skeletal muscle of adult mdx mice using a helper-dependent adenovirus vector expressing the Coxsackievirus and adenovirus receptor(CAR) and dystrophin.
- Author(s)
  Uchida Y., Maeda Y, Kimura E, Yamashita S, Nishida Y, Arima T, Hirano T, Uyama E, Mita S., Uchino M.
- Journal Title
  
  J Gene Med (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590897
[Journal Article] Effective repetitive dystrophin gene transfer into skeletal muscle of adult mdx mice using a helper-dependent adenovirus vector expressing the Coxsackie-virus and adenovirus receptor (CAR) and dystrophin.
- Author(s)
  Uchida Y., Maeda Y, Kimura E, Yamashita S, Nishida Y, Arima T, Hirano T, Uyama E, Mita S., Uchino M.
- Journal Title
  
  J Gene Med (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590897
[Journal Article] Effective repetitive dystrophin gene transfer into skeletal muscle of adult mdx mice using a helper-dependent adenovirus vector expressing the Coxsackie-virus and adenovirus receptor (CAR) and dystrophin.
- Author(s)
  Uchida Y., Maeda Y, Kimura E, Yamashita S, Nishida Y, Arima T, Hirano T, Uyama E, Mita S., Uchino M.
- Journal Title
  
  J Gene Med (in press)
- Data Source
  KAKENHI-PROJECT-15590897
[Presentation] 幹細胞治療による骨格筋再生と筋ジストロフィーの治療研究2010
- Author(s)
  内野克尚
- Organizer
  第28 回日本神経治療学会総会
- Place of Presentation
  横浜(パシフィコ横浜)
- Data Source
  KAKENHI-PROJECT-20200013
[Presentation] Lentiviral vector mediated delivery of full-length dystrophin for gene therapy of muscular dystrophy2010
- Author(s)
  Kimura E, Uchino M, et al.
- Organizer
  13^<th> Annual Meeting of the American Society of Gene and Cell Therapy
- Place of Presentation
  Marriott Wardman Park Hotel Washington DC.アメリカ
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-20591003
[Presentation] 幹細胞治療による骨格筋再生と筋ジストロフィーの治療研究2010
- Author(s)
  内野克尚
- Organizer
  第28回日本神経治療学会総会
- Place of Presentation
  パシフィコ横浜(横浜)
- Data Source
  KAKENHI-PROJECT-20200013
[Presentation] Lentivirat vector mediated delivery of full-length dystrophin for gene therapy of muscular dystrophy2010
- Author(s)
  Kimura E, Uchino M, et al.
- Organizer
  15^<th> International Congress of the world muscle Society
- Place of Presentation
  Kumamoto City Hall, Kumamoto,日本
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-20591003
[Presentation] Lentiviral vector mediated delivery of full-length dystrophin for gene therapy of muscular dystrophy.2010
- Author(s)
  Kimura E, Uchino K, Suga T, Ishizaki M, Koide T, Uchida Y, Maeda Y, Yamashita S, Chamberlain JS, Uchino M.
- Organizer
  13^<th> Annual Meeting of the American Society of Gene and Cell Therapy
- Place of Presentation
  Marriott Wardman Park Hotel, Washington DC, USA.
- Data Source
  KAKENHI-PROJECT-20591003
[Presentation] Effects of emergent neuro-endovascular revascularization on infarct size reduction: Evaluation using sub-6 hour 99mTc-HMPAO SPECT based system2010
- Author(s)
  Hirano T, Watanabe M, Kai Y, Shiraishi S, Kawano H, Uchino M
- Organizer
  19thEuropean Stroke Conference
- Place of Presentation
  Barcelona
- Data Source
  KAKENHI-PROJECT-22590959
[Presentation] Prospective multicenter study on prevention using cilostazol from acute stroke progression. Study design and 1st preliminary report2010
- Author(s)
  Hirano T, Terasaki T, Yonehara T, Takita T, Hashimoto Y, Uchino M
- Organizer
  7th World Stroke Congress
- Place of Presentation
  Seoul
- Data Source
  KAKENHI-PROJECT-22590959
[Presentation] Muscle fiber type-predominant promoter activity in lentiviral-mediated transgenic mouse2010
- Author(s)
  Suga T, Uchino M, et al.
- Organizer
  18^<th> Annual Congress of the European Society of Gene and Cell Therapy
- Place of Presentation
  Stella Polare convention center, Milano,イタリア
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-20591003
[Presentation] 緊急脳血管内血行再建術の病巣縮小効果: 脳血流 SPECT による検討2010
- Author(s)
  平野照之, 渡邉聖樹, 甲斐豊, 白石慎哉, 河野浩之, 内野誠
- Organizer
  第51回日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590959
[Presentation] シンポジウム2.新しい神経治療をめぐってーミオパチー領域における最新の治療戦略2008
- Author(s)
  内野誠
- Organizer
  第26回日本神経治療学会
- Place of Presentation
  新横浜プリンスホテル
- Data Source
  KAKENHI-PROJECT-20591003
[Presentation] Transduction of full-length dystrophin to multiple skeletal muscles improves motor performance and lifespan in utrophin/ dystrophin double knockout mice.2007
- Author(s)
  Ishizaki, M., Kawano, R., Maeda, Y., Uchida, Y., Kimura, E., Uchino, M.
- Organizer
  American Society of Gene Therapy 10th annual meeting
- Place of Presentation
  Seattle, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590951
[Presentation] Transduction of full-length dystrophin to multiple skeletal muscles improves motor performance and lifespan in utrophin/dystrophin double knockout mice2007
- Author(s)
  Ishizaki M, Kawano R., Maeda Y., Kimura E., Uchino M.
- Organizer
  American Sosiety of Gene Terapy
- Place of Presentation
  Seattle
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-18590951
[Presentation] Restoration of physical performance in symptomatic utrophin/ dystrophin double knockout(U/D dko) mice by the helper-dependent adenovirus vector(HDAdv)-mediated full-length dystrophin expression.2006
- Author(s)
  Kawano, R., Ishizaki, M., Uchida, Y., Kimura, E., Maeda, Y., Uchino, M.
- Organizer
  11th European Society of Gene Therapy Annual meeting
- Place of Presentation
  Athens, Greece
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590951
[Presentation] Effective repetitive dystrophin gene transfer into skeletal muscle of adult mdx mice using a helper-dependent adenovirus vector expressing the coxsackievirus and adenovirus receptor(CAR) and dystrophin2005
- Author(s)
  Uchida, Y., Maeda, Y., Kimura, E., Uchino, M.
- Organizer
  American Society of Gene Therapy 9th annual meeting
- Place of Presentation
  Baltimore, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590951

1. MAEDA Yasushi (60346997)

# of Collaborated Projects: 5 results

# of Collaborated Products: 19 results
2. MITA Shuji (30231616)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KIMURA En (60433025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. HIRANO Teruyuki (50346996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. WATANABE Masaki (40530150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

UCHINO Makoto 内野 誠

Research Projects

Research Products

Co-Researchers

Development of SPECT-based objective evaluating system for therapeutic effect of acute revascularization therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ex vivo gene manipulation of mesenchymal stem cell and application to cell therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Helper-dependent adenovirusvector and modified lentiviral vector mediated delivery of dystrophin for gene therapy of muscular dystrophyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene therapy for progressive muscular dystrophy using a new generation adenovirus vector and transposasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene therapy for progressive muscular dystrophy using a new generation adenovirus vector (gutless adenovirus)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the gene therapy using a new generation adenovirus vector (gutless adenovirus)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

BASIC RESEARCH FOR GENE THERAPY OF AMYOTROPHIC LATERAL SCLEROSIS USING ADENOVIRAL VECTORS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the production and purification of a new generation adenovirus vector (gutless adenovirus) and its clinical applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

APOPTOSIS INDUCED BY CYTOCHROME C IN MITOCHONDRIAL DISEASES

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 最新神経病学(分担:筋肉疾患)2008

Author(s)

Total Pages

Publisher

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[Journal Article] Modified ASPECTS for DWI including deep white matter lesions predicts subsequent intra- cranial hemorrhage2012

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DOI

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[Journal Article] Muscle fiber type-predominant promoter activity in lentiviral-mediated transgenic mouse2011

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NAID

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[Journal Article] Rescue from respiratory dysfunction bytransduction of full-length dystrophin to diaphragm via the peritoneal cavity in utrophin/dystrophin double knockout mice.2011

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[Journal Article] Rescue From Respiratory Dysfunction by transduction of Full-length Dystrophin to Diaphragm via the Peritoneal Cavity in Utrophn/Dystrophin Double Knockout Mice2011

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UCHINO Makoto 内野誠