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Mitaka Chieko  三高 千恵子

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… Alternative Names

三高 千恵子  ミタカ チエコ

MITAKA Chieko  三高 千恵子

三高 千惠子  ミタカ チエコ

三高 千恵子.  ミタカ チエコ

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Researcher Number 20126254
Other IDs
External Links
Affiliation (Current) 2025: 順天堂大学, 大学院医学研究科, 特任教授
Affiliation (based on the past Project Information) *help 2021 – 2023: 順天堂大学, 大学院医学研究科, 特任教授
2020: 順天堂大学, 医学(系)研究科(研究院), 特任教授
2017: 東京医科歯科大学, 医歯(薬)学総合研究科, 非常勤講師
2016: 東京医科歯科大学, 大学院医歯学総合研究科, 非常勤講師
2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 非常勤講師 … More
2012 – 2014: 東京医科歯科大学, 医歯(薬)学総合研究科, 准教授
2010 – 2011: 東京医科歯科大学, 大学院・医歯学総合研究科, 准教授
2009: Tokyo Medical and Dental University, 医歯学総合研究科, 准教授
2007 – 2008: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 准教授
2006: 東京医科歯科大学, 大学院医歯学総合研究科, 助教授
1999 – 2005: Tokyo Medical and Dental University, Postgraduate Research Institute, Assistant professor, 大学院・医歯学総合研究科, 助教授
1999: 東京医科歯科大学, 医学部, 助教授
1998: 東京医科歯科大学, 医学部・附属病院, 講師
1997: 東京医科歯科大学, 医学部, 講師
1995: Tokyo Medical and Dental University, Intensive Care Unit, Instructor, 医学部, 講師
1994: 東京医科歯科大学, 集中治療部, 講師
1993: 東京医科歯科大学, 集中治療部, 助手 Less
Review Section/Research Field
Principal Investigator
Anesthesiology/Resuscitation studies / Emergency medicine / Basic Section 55060:Emergency medicine-related
Except Principal Investigator
Anesthesiology/Resuscitation studies / Emergency medicine / Anesthesiology
Keywords
Principal Investigator
エンドトキシンショック / 敗血症性ショック / N2733 / NO synthase inhibitor / Endothelin / 血行動態 / エンドトキシン / エンドセリン / NO合成酵素阻害薬 / 敗血症 … More / 多臓器障害 / 重症患者 / 尿中好中球ゼラチナーゼ結合性リポカリン / 腎酸素飽和度 / 臓器不全 / 好中球ゼラチナーゼ結合性リポカリン / 局所酸素飽和度 / ショック / 急性腎障害 / pyrrolidinone derivative / multiple organ failure / endotoxin / septic shock / Inhibitor of NF-kB / 誤嚥性肺炎 / 心筋虚血・再灌流障害 / pyrrolidine dithiocarbamate / NF-κB阻害薬 / ピロリディノン誘導体 / NF-kB阻害剤 / Post operation of abdominal aortic aneurysm / Renal function / Renal blood flow / Hemodynamics / Endothelin receptor antagonist / Endotoxic shock / エンドセリン受容体桔抗薬 / 臓器障害 / 低酸素症 / 呼吸機能障害 / L-カナヴァニン / エンドトキシンシッョク / 腹部大動脈瘤術後 / 腎機能 / 腎血流量 / エンドセリン受容体拮抗薬 / Aminoguanidine / N^G-nitro-L-arginine / Nitric oxide / Tumor necrosis factor-alpha / Sepsis / Endotoxin shock / エンドセリン-1 / リポポリサッカライド(LPS) / プロスタサイクリン / エンドリセン / ニトロアルギニン / アミノグアニジン / ニトロアルキニン / 一酸化窒素(NO) / 腫瘍壊死因子(TNF-α) / 多臓器不全症候群 / 虚血・再灌流障害 / 抗炎症反応 / 多臓器障害症候群 / 虚血・再灌流傷害 / 造影剤腎症 / 腎虚血•再灌流 / 造影剤 / 虚血再灌流傷害 / 炎症 / サイトカイン / 心房性ナトリウム利尿ペプチド / 急性腎傷害 / 一酸化窒素 / ポリ(ADP-リポース)シンターゼ / 代謝性アシドーシス / ARDS / ポリ(ADP-リボース)シンセターゼ / 3-aminobenzamide / Poly(ADP-ribose)synthetase / 炎症性サイトカイン / Poly (ADP-ribose) synthetase … More
Except Principal Investigator
サイトカイン / RT-PCR / 誘導型NO合成酵素 / 敗血症性ショック / cell free DNA / 好中球 / 血液凝固 / 急性腎障害 / 臓器障害 / 周術期腎障害 / 細胞外トラップ / inflammatory cytokines / unilateral ischemia / cyotokine / isolated rat lung / ischemia-reperfusion / mRNA / 遊離潅流肺標本 / 肺循環 / 虚血・再潅流障害 / IL-6 / IL-1 beta / 低酸素症 / 虚血・再環流障害 / 肺遊離環流標本 / Interferon-γ / Inteferon-γ / IL-10 / 遊離肺還流標本 / 好炎症性サイトカイン / 虚血・再還流障害 / DAMPs・PAMPs / PAI-1 / 敗血症 / 心臓手術 / 周術期 / 急性肺傷害 / バイオマーカー / IkB / NO / NF-kB / 遺伝子治療 / アンチセンスオリゴマー / 血管平滑筋 / 一酸化窒素(NO) Less
  • Research Projects

    (12 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (12 People)
  •  Kidney oxygen saturation as a novel marker for acute kidney injury in critically ill patientsPrincipal Investigator

    • Principal Investigator
      三高 千恵子
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Juntendo University
  •  Relationship between perioperative neutrophil extracellular trap formation and organ dysfunction

    • Principal Investigator
      UCHIDA Tokujiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Biomarker profiles of perioperative acute lung injury

    • Principal Investigator
      Mamoru Yamamoto
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      Tokyo Medical and Dental University
  •  敗血症性ショックの凝固能調節による治療法開発の検討

    • Principal Investigator
      原口 剛
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Mechanism of protective effects of atrial natriuretic peptide on acute kidney injuryPrincipal Investigator

    • Principal Investigator
      MITAKA Chieko
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Strategy for treatment of septic shock by poly (ADP-ribose) synthetase inhibitorPrincipal Investigator

    • Principal Investigator
      MITAKA Chieko
    • Project Period (FY)
      2006 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Treatment strategy of septic shock by inhibition of transcription factor, NF-kBPrincipal Investigator

    • Principal Investigator
      MITAKA Chieko
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Tokyo Medical and Dental University
  •  NF-kB活性化経路の特異的阻害による敗血症性ショックの遺伝子治療

    • Principal Investigator
      平田 結喜緒
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Tokyo Medical and Dental University
  •  誘導型NO合成酵素発現の特異的阻害による敗血症性ショックの遺伝子治療

    • Principal Investigator
      平田 結喜緒
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Tokyo Medical and Dental University
  •  Elucidation of pathophysiology of ischemia reperfusion injury jn isolated perfused rat lungs

    • Principal Investigator
      IMAI Takasuke
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Tokyo Medical & Dental University
  •  Relationship between endothelin and organ dysfunction in SIRSPrincipal Investigator

    • Principal Investigator
      MITAKA Chieko
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Tokyo Medical and Dental University
  •  Effects of N^G-nitro-L-arginine on hemodynamic changes in endotoxin shockPrincipal Investigator

    • Principal Investigator
      MITAKA Chieko
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Tokyo Medical and Dental University

All 2017 2016 2014 2009 2008 2007 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] Perioperative Elevation in Cell-Free DNA Levels in Patients Undergoing Cardiac Surgery: Possible Contribution of Neutrophil Extracellular Traps to Perioperative Renal Dysfunction.2016

    • Author(s)
      Qi Y, Uchida T, Yamamoto M, Yamamoto Y, Kido K, Ito H, Ohno N, Asahara M, Yamada Y, Yamaguchi O, Mitaka C, Tomita M, Makita K.
    • Journal Title

      Anesthesiol Res Pract

      Volume: 2016 Pages: 2794364-2794364

    • DOI

      10.1155/2016/2794364

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05004, KAKENHI-PROJECT-25462427
  • [Journal Article] Atrial natriuretic peptide attenuates kidney-lung crosstalk in kidney injury2014

    • Author(s)
      Tulafu M, Mitaka C, Hnin Si MK, Abe S, Kitagawa M, Ikeda S, Eishi Y, Kurata S, Tomita M
    • Journal Title

      J Surg Res

      Volume: 186 Issue: 1 Pages: 217-225

    • DOI

      10.1016/j.jss.2013.07.033

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-22592010, KAKENHI-PROJECT-24592827, KAKENHI-PROJECT-25860290
  • [Journal Article] Effects of atrial natriuretic peptide on inter-organ crosstalk among the kidney, lung, and heart in a rat model of renal ischemia-reperfusion injury2014

    • Author(s)
      Mitaka C, Hnin Si MK, Tulafu M, Qi Y, Uchida T, Abe S, Kitagawa M, Ikeda S, Eishi Y, Tomita M
    • Journal Title

      Intensive Care Medicine Experimental

      Volume: 2 Issue: 1 Pages: 28-44

    • DOI

      10.1186/s40635-014-0028-8

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-22592010, KAKENHI-PROJECT-23390411
  • [Journal Article] A longer duration of polymyxin-B-immobilized fiber column hemoperfusion improves pulmonary oxygenation in patients with septic shock2009

    • Author(s)
      Chieko Mitaka, et al.
    • Journal Title

      Shock 32

      Pages: 478-483

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591978
  • [Journal Article] A longer duration of polymyxin B immobilized fiber column hemoperfusion improves pulmonary oxygenation in patients with septic shock2009

    • Author(s)
      Mitaka C, Tsuchida N, Kawada K, Nakajima Y.
    • Journal Title

      Shock 32

      Pages: 478-483

    • Data Source
      KAKENHI-PROJECT-18591978
  • [Journal Article] Effects of human atria lnatriuretic peptide on renal function in patients under going abdominal aortic aneurysm repair2008

    • Author(s)
      Mitakac, Kudo T, Jibiki M, Sugano N, Inoue Y, Makita K, Imai T
    • Journal Title

      Crit Care Med 36

      Pages: 745-751

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591978
  • [Journal Article] Effect of human natriuretic peptide on renal function in patients undergoing abdominal aortic aneurysm repair2008

    • Author(s)
      Mitaka C, Kudo T, Jibiki M, Sugano N, Inoue Y, Makita K, Imai T.
    • Journal Title

      Crit Care Med 30

      Pages: 745-751

    • Data Source
      KAKENHI-PROJECT-18591978
  • [Journal Article] Nitric oxide production is more prominent in off-pump than in on-pump coronary artery bypass surgery.2007

    • Author(s)
      Mitaka C, Yokoyama K, Imai T.
    • Journal Title

      Anaesth Intensive Care 35

      Pages: 505-509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591978
  • [Journal Article] Nitric oxide production is more prominent in off-pump than in on-pump coronary artery bypass surgery2007

    • Author(s)
      Mitaka C, Yokoyama K, Imai T.
    • Journal Title

      Anaesth Intensive Care 35

      Pages: 505-509

    • Data Source
      KAKENHI-PROJECT-18591978
  • [Journal Article] Blockade of nuclear factor-kB activation prevents hypodynamic shock and gastric hypoperfusion induced by endotoxin in anesthetized dogs2005

    • Author(s)
      Chieko Mitaka, et al.
    • Journal Title

      Intensive Care Med 31

      Pages: 718-723

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571423
  • [Journal Article] Clinical laboratory differentiation of infectious versus non-infectious systemic inflammatory response syndrome2005

    • Author(s)
      Chieko Mitaka
    • Journal Title

      Clinica Chimca Acta 351

      Pages: 17-29

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571423
  • [Journal Article] Clinical laboratory differentiation of infectious versus non-infectious systemic inflammatory response syndrome2005

    • Author(s)
      Chieko Mitaka
    • Journal Title

      Clinica Chimica Acta 351

      Pages: 17-29

    • Data Source
      KAKENHI-PROJECT-14571423
  • [Journal Article] Clinical laboratory differentiation of infectious versus non-infectious systemic inflammatory response syndrome2005

    • Author(s)
      Chieko Mitaka, et al.
    • Journal Title

      Clinica Chimica Acta 351

      Pages: 17-29

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571423
  • [Journal Article] Blockade of nuclear factor-κB activation prevents hypodynamic shock and gastric hypoperfusion induced by endotoxin in anesthetized dogs2005

    • Author(s)
      Chieko Mitaka, et al.
    • Journal Title

      Intensive Care Med 31

      Pages: 718-723

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571423
  • [Journal Article] Septic shock and endothelin2004

    • Author(s)
      Chieko Mitaka
    • Journal Title

      Nippon Rinsho 62(Suppl 9)

      Pages: 661-664

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571423
  • [Journal Article] 病態と疾患からみたNO、敗血症性ショック2004

    • Author(s)
      三高千惠子
    • Journal Title

      日本臨床 62巻 増刊号9

      Pages: 540-543

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571423
  • [Journal Article] Septic shock and NO2004

    • Author(s)
      Chieko Mitaka
    • Journal Title

      Nippon Rinsho 62(Suppl 9)

      Pages: 540-543

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571423
  • [Journal Article] 病態と疾患からみたNO,敗血症性ショック2004

    • Author(s)
      三高千恵子
    • Journal Title

      日本臨床 62 Suppl 9

      Pages: 540-543

    • Data Source
      KAKENHI-PROJECT-14571423
  • [Journal Article] 病態と疾患からみたエンドセリン、敗血症性ショック2004

    • Author(s)
      三高千惠子
    • Journal Title

      日本臨床 62巻 増刊号9

      Pages: 661-664

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571423
  • [Journal Article] Blockade or nuclear factor-κB activation prevents hypodynamic shock and gastric hypoperfusion induced by endotoxin in anesthetized dogs

    • Author(s)
      Chieko Mitaka, et al.
    • Journal Title

      Intensive Care Med (in press)

    • Data Source
      KAKENHI-PROJECT-14571423
  • [Presentation] シンポジウム AKIの治療法: 心房性Na利尿ペプチド2017

    • Author(s)
      内田篤治郎、三高千恵子
    • Organizer
      日本麻酔科学会第64回学術集会
    • Data Source
      KAKENHI-PROJECT-15H05004
  • [Presentation] Polynyxin B-immobilized fiber column hemoperfusion has the possibility to reduce endothelial activation in patients with septic shock. Effect of endotoxin adsorption therapy on hemodynamics, procaicitonin and C-reactive protein in patients with septic shock.2008

    • Author(s)
      Mitaka C, Fuji Y, Nakajma Y, Kawada K, lmai T Mitaka C, Tsuchiya K, Kawada K, Nakajima Y, Imai T
    • Organizer
      21^<th> Annual Congress of European Society of Intensive Care Medicine
    • Place of Presentation
      Lisbon, Portugal
    • Year and Date
      2008-09-23
    • Data Source
      KAKENHI-PROJECT-18591978
  • [Presentation] Beneficial effects of human atrial natriuretic peptide on renal function in patients undergoing abdominal aortic aneurysm repair.2007

    • Author(s)
      Chieko Mitaka
    • Organizer
      20th Annual Congress, European Society of Intensive care medicine
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2007-10-07
    • Data Source
      KAKENHI-PROJECT-18591978
  • [Presentation] Atrial natriuretic peptide attenuates contrast-induced nephropathy in rats

    • Author(s)
      Chieko Mitaka
    • Organizer
      第41回日本集中治療医学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22592010
  • 1.  UCHIDA Tokujiro (40262183)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 2.  TSUNODA Yukio (30092422)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  NAGURA Takashi (80192243)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  平田 結喜緒 (50135787)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  七里 真義 (10206097)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  Mamoru Yamamoto (90422477)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  IMAI Takasuke (60091964)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KURATA Shyunichi (60140901)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  NOSAKA Toshihisa (20313257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  原口 剛 (40361729)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  槇田 浩史 (20199657)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  槙田 浩史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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