YOKOCHI Takashi 横地高志

Researcher Number	20126915
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2014 – 2015: 愛知医科大学, 医学部, 名誉教授 2010 – 2013: 愛知医科大学, 医学部, 教授 2005 – 2008: 愛知医科大学, 医学部, 教授 1990 – 2003: 愛知医科大学, 医学部, 教授 1989 – 1990: 福井医科大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Bacteriology (including Mycology) / 細菌学 / Bacteriology (including mycology) Except Principal Investigator Bacteriology (including Mycology) / 細菌学 / 電子機器工学 / Neurology
Keywords	Principal Investigator LPS / エンドトキシン / endotoxin / 一酸化窒素 / lipopolysaccharide / マクロファージ / p53 / NF-kappaB / エンドトキシンショック / アポトーシス … More / HSP / リポ多糖体 / アジュバント活性 / macrophage / nuclear factor-kappaB / nitric oxide / endotoxic shock / TNF / apoptosis / 肝細胞 / サイトカイン / レクチン / クレブシエラ / 内毒素 / 補体 / DNA damage / anti-cancer drug / doxorubicin / マクロブァージ / アドレアマイシン / 抗がん剤 / activated protein C / NO合成酵素 / p38 / NO / ガンマインターフェロン / 活性化プロテインC / END-D cell / inducible type NO synthase / interferon-gamma / vascular endothelial cell / DIC / HUVEC / TF / 組織因子 / CD14 / 血管内皮細胞 / BAEC / p38 MAPキナーゼ / ウシ血管内皮細胞 / 内皮傷害 / 細胞外マトリックス / hepatocyte / stress response / マウス / ストレス蛋白 / TNFi / peroxynitrite / ニトロチロシン / iNOS / ストレスタンパク / PYHIN1 / インターフェロンβ / インターフェロン-β / MyD88非依存性 / pyhin1 / TNF-alpha / RAW264.7 / retinoblastoma protein-interacting zinc finger1 / 癌遺伝子 / MAPK / がん遺伝子 / RIZ1 / 炎症性メディエーター / RAW264.7 NF-kappaB / ASAP1 / VLA4細胞 / VCAM-1 / 腫瘍壊死因子 / 血管透過性 / 腫瘍懐死因子 / インターフェロン / NKT細胞 / ガラクトシルセラミド / D-ガラクトサミン / ストレス応答 / 熱ショック蛋白 / マンナン / MBP / マンノース結合蛋白 / プログラム細胞死 / 胸腺 / アポトージス / IL-2 / 肺炎桿菌 / マンノ-ス結合蛋白 … More Except Principal Investigator MIP-1α / NF-κB / STAT1 / p38 MAPK / IP-10 / IFN-α / PDC / CpG DNA / Ganglioside / Astrocyte / Oligodendrocyte / Lysosomal enzyme / PDGF / Trapidil / Dibutyryl cyclic AMP / ISGF3 / IRF-7 / INF-α / Bacterial DNA / p38MAPK / PI3K / endosomal maturation / MIP-1alpha / IFN-alpha / Plasmacytoid Dendritic Cells / CpG-DNA / Cytotoxic toxins / Exotoxin / Lipopolysaccharide / Endotoxin / Bacterial toxins / GPIアンカー / 蛋白毒素 / LPS / 細胞傷害 / 細胞毒 / 外毒素 / リポ多糖 / 内毒素 / 細菌毒素 / Diagnostic procedures / Sheath-flow thechiques / An application for N_2 Laser / Identification for bacteria / Flow-image-analysis / Automatic / 画像処理 / フロ-方式 / 細菌 / 診断法 / シ-スフロ-技術 / 窒素レ-ザの応用 / 細菌の識別 / フロ-方式の画像解析 / 自動分類 / アストロサイト / ガングリオシド / シバラ-マウス / 移植 / サイクリッリAMP / オリゴデンドロサイト / 細胞培養 / グリア細胞 / Gangliosicle / Astro cyto / Oligo dendrocyte / AP-1 / Bリンパ球 / 膠原菌 / B1リンパ球 / 自己免疫疾患 / MAPキナーゼ / BMK1 / 細菌内毒素 Less

Crosstalk between pifitlin-a and LPS-mediated inflammatory responsePrincipal Investigator
- Principal Investigator
  
  Yokochi Takashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Aichi Medical University
Role of tumor-suppressive genes on LPS-induced inflammatory responsePrincipal Investigator
- Principal Investigator
  
  YOKOCHI Takashi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Aichi Medical University
Establishment of a new experimental model for human septic shockPrincipal Investigator
- Principal Investigator
  
  YOKOCHI Takashi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Aichi Medical University
The mechanism of the inhibitory action of lipopolysaccharide on anti-cancer drug-induced cell injuryPrincipal Investigator
- Principal Investigator
  
  YOKOCHI Takashi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  AICHI MEDICAL UNIVERSITY
Effect of activated protein C on LPS-induced nitric oxide productionPrincipal Investigator
- Principal Investigator
  
  YOKOCHI Takashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  AICHI MEDICAL UNIVERSITY
Identification of immunostimulatory CpG DNA and its activation mechanism in human immune-conmpetent cells
- Principal Investigator
  
  IHO Sumiko
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  福井医科大学
BMK1は細菌内毒素によるBリンパ球活性化を制御する
- Principal Investigator
  
  加藤豊
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Aichi Medical University
The mechanism of endotoxin-induced vascular endothelial injuryPrincipal Investigator
- Principal Investigator
  
  YOKOCHI Takashi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Aichi Medical University School of Medicine
THE ROLE OF STRESS PROTEINS IN ENDOTOXIN-INDUCED HEPATIC INJURYPrincipal Investigator
- Principal Investigator
  
  YOKOCHI Takashi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  AICHI MEDICAL UNIVERSITY
実験的エンドトキシンショックにおけるアポトーシスの関与Principal Investigator
- Principal Investigator
  
  横地高志
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Aichi Medical University
細菌内毒素投与による熱ショック蛋白誘導機序Principal Investigator
- Principal Investigator
  
  横地高志
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Aichi Medical University
肺炎桿菌リポ多糖体の強力な補体活性化能におけるマンナン結合蛋白の役割Principal Investigator
- Principal Investigator
  
  横地高志
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Aichi Medical University
エンドトキシン投与によるマウス胸腺におけるアポトージスPrincipal Investigator
- Principal Investigator
  
  横地高志
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Aichi Medical University
インターロイキン2の細菌内毒素への結合Principal Investigator
- Principal Investigator
  
  横地高志
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  細菌学
- Research Institution
  Aichi Medical University
Molecular mechanisms of bacterial toxins on host cells
- Principal Investigator
  
  NAKANO Masayasu
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  細菌学
- Research Institution
  Jichi Medical School
肺炎桿菌リポ多糖体の極めて強い補体活性化能におけるマンノ-ス結合蛋白の役割Principal Investigator
- Principal Investigator
  
  横地高志
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  細菌学
- Research Institution
  Aichi Medical University
Study of Cultured Glial Cells
- Principal Investigator
  
  HIRAYAMA Mikio
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Fukui Medical School
An automatic bacteria classification system
- Principal Investigator
  
  TANIGUCHI Keiji
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  電子機器工学
- Research Institution
  Dept. of Information Science, Faculty of Engineering, Fukui University

All 2015 2014 2012 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] Inhibition of RANKL- and LPS-induced osteoclast differentiations by novel NF-κB inhibitor DTCM-glutarimide.2015
- Author(s)
  Koide N, Kaneda A, Yokochi T, Umezawa K.
- Journal Title
  
  Int Immunopharmacol.
  
  Volume: 25 Issue: 1 Pages: 162-168
- DOI
  10.1016/j.intimp.2015.01.004
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460550, KAKENHI-PROJECT-25460551
[Journal Article] Pretreatment of LPS inhibits IFN-β-induced STAT1 phosphorylation through SACS3 induced by LPS2015
- Author(s)
  Ando T, Komatsu T, Naiki Y, Yokochi T, Watanabe D, Koide N
- Journal Title
  
  Biomed Pharmacother.
  
  Volume: 76 Pages: 1-5
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460551
[Journal Article] TGF‐1 inhibits the production of IFN in response to CpG DNA via ubiquicination of TNF receptor-associated factor(TRAF)62015
- Author(s)
  Naiki Y, Komatsu T, Koide N, Dagvadorji J, Yoshida T, Arditi M, Yokochi T.
- Journal Title
  
  Innate Immun.
  
  Volume: 21 Issue: 7 Pages: 770-777
- DOI
  10.1177/1753425915596844
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460551
[Journal Article] Poly I:C enhances production of nitric oxide in response to interferon-γ via upregulation of interferon regulatory factor 7 in vascular endothelial cells.2015
- Author(s)
  Mori D, Koide N, Tsolmongyn B, Nagata H, Sano T, Nonami T, Yokochi T.
- Journal Title
  
  Microvasc Res.
  
  Volume: 9 Pages: 68-73
- DOI
  10.1016/j.mvr.2015.01.003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460551
[Journal Article] Involvement of redox balance in in vitro osteoclast formation of RAW 264.7 macrophage cells in response to LPS.2015
- Author(s)
  Odkhuu E, Koide N, Tsolmongyn B, Jambalganiin U, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
- Journal Title
  
  Innate Immun.
  
  Volume: 21 Issue: 2 Pages: 194-202
- DOI
  10.1177/1753425914524242
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460551
[Journal Article] Irbesartan attenuates production of high-mobility group box 1 in response to lipopolysaccharide via downregulation of interferon-β production.2015
- Author(s)
  Kato Y, Kamiya H, Koide N, Odkhuu E, Komatsu T, Watarai A, Kondo M, Kato K, Nakamura J, Yokochi T.
- Journal Title
  
  Int Immunopharmacol.
  
  Volume: 26 Issue: 1 Pages: 97-102
- DOI
  10.1016/j.intimp.2015.03.015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460551
[Journal Article] Lipopolysaccharide downregulates the expression of p53 through activation of MDM2　and enhances activation of nuclear factor-kappa B2015
- Author(s)
  Odkhuu E, Mendjargal A, Koide N, Naiki Y, Komatsu T, Yokochi T
- Journal Title
  
  Immunobiology
  
  Volume: 220 Issue: 1 Pages: 136-141
- DOI
  10.1016/j.imbio.2014.08.010
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460551
[Journal Article] Lipopolysaccharide impairs insulin sensitivity via activation of phosphoinositide 3-kinase in adipocytes2014
- Author(s)
  Wakayama S, Haque A, Koide N, Kato Y, Odkhuu E, Bilegtsaikhan T, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
- Journal Title
  
  Immunopharmacol Immunotoxicol.
  
  Volume: ３６ Issue: 2 Pages: 145-149
- DOI
  10.3109/08923973.2014.887096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460551
[Journal Article] Mouse pyrin and HIN domain family member 1 (pyhin1) protein positively regulates LPS-induced IFN-β and NO production in macrophages2014
- Author(s)
  Haque A, Koide N, Odkhuu E, Tsolmongyn B, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
- Journal Title
  
  Innate Immun
  
  Volume: ２０ Issue: 1 Pages: 40-48
- DOI
  10.1177/1753425913481636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460551
[Journal Article] Sendai virus C protein　inhibits lipopolysaccharide-induced nitric oxide production through impairing interferon-β signaling2014
- Author(s)
  Odkhuu E, Komatsu T, Naiki Y, Koide N, Yokochi T
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 23 Issue: 1 Pages: 267-272
- DOI
  10.1016/j.intimp.2014.09.012
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460551
[Journal Article] A novel mechanism for inhibition of lipopolysaccharide-induced proinflammatory cytokine production by valproic acid2014
- Author(s)
  Jambalganiin U, Tsolmongyn B, Koide N, Odkhuu E, Naiki Y, Komatsu T, Yoshida T, Yokochi T
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 20 Issue: 1 Pages: 181-187
- DOI
  10.1016/j.intimp.2014.02.032
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460551
[Journal Article] Spironolactone inhibits production of proinflammatory mediators in response to lipopolysaccharide via inactivation of　nuclear factor-κB2014
- Author(s)
  Kato Y, Kamiya H, Koide N, Odkhuu E, Komatsu T, Dagvadorj J, Watarai A, Kondo, M, Kato K, Nakamura J, Yokochi T
- Journal Title
  
  Immunopharmacol Immunotoxicol
  
  Volume: 36 Issue: 3 Pages: 237-241
- DOI
  10.3109/08923973.2014.921690
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460551
[Journal Article] Inhibition of receptor activator of nuclear factor-κB ligand- or lipopolysaccharide-induced osteoclast formation by conophylline through downregulation of CREB.2014
- Author(s)
  Koide N, Kondo Y, Odkhuu E, Ulziisaikhan J, Ukaji T, Yokochi T, Umezawa K.
- Journal Title
  
  Immunol Lett.
  
  Volume: １６１ Issue: 1 Pages: 31-37
- DOI
  10.1016/j.imlet.2014.04.006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460550, KAKENHI-PROJECT-25460551
[Journal Article] A new experimental murine model for lipopolysaccharide-mediated lethal shock with lung injury2012
- Author(s)
  Yokochi T
- Journal Title
  
  Innate Immun
  
  Volume: 18 Issue: 2 Pages: 364-370
- DOI
  10.1177/1753425911410236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590408
[Journal Article] An ADP ribosylationfactor-GTPase activating protein negatively regulates the production of proinflammatory mediators in response to lipopolysaccharide.2011
- Author(s)
  Haque A, Noman AS, Koide N, Odkhuu E, Naiki Y, Hashimoto S, Komatsu T, Yoshida T, Yokochi T.
- Journal Title
  
  Cancer Immunol Immunother.
  
  Volume: 60 Issue: 10 Pages: 1439-46
- DOI
  10.1007/s00262-011-1048-9
- Data Source
  KAKENHI-PROJECT-22590408
[Journal Article] Retinoblastoma protein-interacting zinc finger 1, a tumor suppressor, augments lipopolysaccharide-induced proinflammatory cytokine production via enhancing nuclear factor-kappaB activation.2010
- Author(s)
  Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, KomatsuT, Yoshida T, Yokochi T.
- Journal Title
  
  Cell Immunol
  
  Volume: 264 Issue: 2 Pages: 114-8
- DOI
  10.1016/j.cellimm.2010.05.007
- Data Source
  KAKENHI-PROJECT-22590408
[Journal Article] Seladin-1 is a novel lipopolysaccharide (LPS)-responsive geneand inhibits the tumour necrosis factor-alpha production and osteoclast formation in response to LPS.2010
- Author(s)
  Khuda II, Koide N, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
- Journal Title
  
  Immunology
  
  Volume: 131 Issue: 1 Pages: 59-66
- DOI
  10.1111/j.1365-2567.2010.03274.x
- Data Source
  KAKENHI-PROJECT-22590408
[Journal Article] Retinoblastoma protein-interacting zinc finger 1 (RIZ1)regulates the proliferation of monocytic leukemia cells via activation of p53.2010
- Author(s)
  Shadat NM, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
- Journal Title
  
  Cancer Invest.
  
  Volume: 28 Issue: 8 Pages: 806-12
- DOI
  10.3109/07357907.2010.494323
- Data Source
  KAKENHI-PROJECT-22590408
[Journal Article] Retinoblastoma protein-interacting zinc finger 1 (RIZ1) participates in RANKL-induced osteoclast formation via regulation of NFATc1expression.2010
- Author(s)
  Noman AS, Koide N, Iftakhar-E-Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
- Journal Title
  
  Immunol Lett.
  
  Volume: 131 Issue: 2 Pages: 166-9
- DOI
  10.1016/j.imlet.2010.04.006
- Data Source
  KAKENHI-PROJECT-22590408
[Journal Article] Concanavalin A induces formation of osteoclast-like cells in RAW 264.7 mouse macrophage cells2009
- Author(s)
  Kasugai C, Morikawa A, Naiki Y, Koide N, Komatsu T, Yoshida T, Yokochi T.
- Journal Title
  
  Immunopharmacol Immunotoxicol 2008 31
  
  Pages: 103-7
- Data Source
  KAKENHI-PROJECT-19590461
[Journal Article] Role of V{alpha}14+ NKT cells in the development of Hepatitis B virus-specific CTL : activation of V{alpha}14+ NKT cells promotes the breakage of CTL tolerance2008
- Author(s)
  Ito H, Ando K, Ishikawa T, Nakayama T, Taniguchi M, Saito K, Imawari M, Moriwaki H, Yokochi T, Kakumu S, Seishima M.
- Journal Title
  
  Int Immunol 20
  
  Pages: 869-79
- Data Source
  KAKENHI-PROJECT-19590461
[Journal Article] Hydrogen peroxide induces the production of tumor necrosis factor-{alpha} in RAW 264.7 macrophage cells via activation of p38 and stress-activated protein kinase2008
- Author(s)
  Nakao N, Kurokawa T, Nonami T, Tumurkhuu G, Koide N, Yokochi T.
- Journal Title
  
  Innate Immun 14
  
  Pages: 190-6
- Data Source
  KAKENHI-PROJECT-19590461
[Journal Article] Interleukin-10 inhibits tumor necrosis factor-alpha production in lipopolysaccharide -stimulated RAW 264.7 cells through reduced MyD88 expression2008
- Author(s)
  Dagvadorj J, Naiki Y, Tumurkhuu G, Hassan F, Islam S, Koide N, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  Innate Immun 14
  
  Pages: 109-15
- Data Source
  KAKENHI-PROJECT-19590461
[Journal Article] Lipopolysaccharide augments the in vivo lethal action of doxorubicin against mice via hepatic damage2008
- Author(s)
  Hassan F, Morikawa A, Islam S, Tumurkhuu G, Dagvadorj J, Koide N, Naiki Y, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  Clin Exp Immunol 151
  
  Pages: 334-40
- Data Source
  KAKENHI-PROJECT-19590461
[Journal Article] The mechanism of development of acute lung injury in lethal endotoxic shock using alpha-galactosylceramide (alpha-GalCer) sensitization2008
- Author(s)
  Tumurkhuu G, Koide N, Dagvadorj J, Morikawa A, Hassan F, Islam S, Naiki Y, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  Clin Exp Immunol 152
  
  Pages: 182-91
- Data Source
  KAKENHI-PROJECT-19590461
[Journal Article] Thalidomide inhibits epidermal growth factor-induced cell growth in mouse and human monocytic leukemia cells via Ras inactivation2008
- Author(s)
  Noman AS, Koide N, Khuda II, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T.
- Journal Title
  
  Biochem Biophys Res Commun 374
  
  Pages: 683-7
- Data Source
  KAKENHI-PROJECT-19590461
[Journal Article] MnTBAP, a synthetic metalloporphyrin, inhibits production of tumor necrosis factor-alpha in lipopolysaccharide-stimulated RAW 264.7 macrophages cells via inhibiting oxidative stress-mediating p38 and SAPK/JNK signaling2007
- Author(s)
  Tumurkhuu G, Koide N, Dagvadorj J, Hassan F, Islam S, Naiki Y, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  FEMS Immunol Med Microbiol 49
  
  Pages: 304-11
- Data Source
  KAKENHI-PROJECT-19590461
[Journal Article] Lipopolysaccharide and interferon-gamma enhance Fas-mediated cell death in mouse vascular endothelial cells via augmentation of Fas expression2007
- Author(s)
  Koide N, Morikawa A, Tumurkhuu G, Dagvadorj J, Hassan F, Islam S, Naiki Y, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  Clin Exp Immunol 150
  
  Pages: 553-60
- Data Source
  KAKENHI-PROJECT-19590461
[Journal Article] Bacterial lipopolysaccharide induces osteoclast formation in RAW 264.7 macrophage cells2007
- Author(s)
  Islam S, Hassan F, Tumurkhuu G, Dagvadorj J, Koide N, Naiki Y, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  Biochem Biophys Res Commun 360
  
  Pages: 346-51
- Data Source
  KAKENHI-PROJECT-19590461
[Journal Article] Characterization of biological activities of Brucella melitensis lipopolysaccharide.2006
- Author(s)
  Tumurkhuu G, Koide N, Takahashi K, Hassan F, Islam S, Ito H, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  Microbiol Immunol. 50
  
  Pages: 421-7
- NAID
  10019169150
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590404
[Journal Article] Lethal endotoxic shock using alpha-galactosylceramide sensitization as a new experimental model of septic shock.2006
- Author(s)
  Ito H, Koide N, Hassan F, Islam S, Tumurkhuu G, Mori I, Yoshida T, Kakumu S, Moriwaki H, Yokochi T.
- Journal Title
  
  Lab Invest. 86
  
  Pages: 254-61
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590404
[Journal Article] Intracellular expression of toll-like receptor 4 in neuroblastoma cells and their unresponsiveness to lipopolysaccharide.2006
- Author(s)
  Hassan F, Islam S, Tumurkhuu G, Naiki Y, Koide N, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  BMC Cancer. 6
  
  Pages: 281-281
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590404
[Journal Article] Involvement of Kupffer cells in lipopolysaccharide-induced rapid accumulation of platelets in the liver and the ensuing anaphylaxis-like shock in mice.2006
- Author(s)
  Yamaguchi K, Yu Z, Kumamoto H, Sugawara Y, Kawamura H, Takada H, Yokochi T, Sugawara S, Endo Y.
- Journal Title
  
  Biochim Biophys Acta. 1762
  
  Pages: 269-75
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590404
[Journal Article] Lipopolysaccharide prevents apoptosis induced by brefeldin A, an endoplasmic reticulum stress agent, in RAW 264.7 cells.2006
- Author(s)
  Islam S, Hassan F, Tumurkhuu G, Ito H, Koide N, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  Biochem Biophys Res Commun. 340
  
  Pages: 589-96
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590404
[Journal Article] Augmentation of lipopolysaccharide-induced nitric oxide production by alpha-galactosylceramide in mouse peritoneal cells.2005
- Author(s)
  Ito H, Koide N, Morikawa A, Hassan F, Islam S, Tumurkhuu G, Mori I, Yoshida T, Kakumu S, Moriwaki H, Yokochi T.
- Journal Title
  
  J Endotoxin Res. 11
  
  Pages: 213-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590404
[Journal Article] Lipopolysaccharide prevents doxorubicin-induced apoptosis in RAW 264.7 macrophage cells by inhibiting p53 activation.2005
- Author(s)
  Hassan F, Islam S, Mu MM, Ito H, Koide N, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  Mol Cancer Res. 3
  
  Pages: 373-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590404
[Journal Article] Inhibition of extracellular signal-regulated kinase 1/2 augments nitric oxide production in lipopolysaccharide-stimulated RAW264.7 macrophage cells.2005
- Author(s)
  Koide N, Ito H, Mu MM, Sugiyama T, Hassan F, Islam S, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  FEMS Immunol Med Microbiol. 45
  
  Pages: 213-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590404
[Journal Article] A role of mitogen and stress-activated protein kinase 1/2 in survival of lipopolysaccharide-stimulated RAW 264.7 macrophages.2005
- Author(s)
  Mu MM, Koide N, Hassan F, Islam S, Sugiyama T, Ito H, Mori I, Yoshida T, Yokochi T.
- Journal Title
  
  FEMS Immunol Med Microbiol. 43
  
  Pages: 277-86
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590404
[Journal Article] Serum-dependent potentiation of lipopolysaccharide-induced nitric oxide production is mediated by the events after the transcription of inducible type of nitric oxide synthase.2005
- Author(s)
  Zhang YH, Murphy WJ, Russell SW, Morrison DC, Koide N, Yoshida T, Yokochi T.
- Journal Title
  
  Cell Immunol. 234
  
  Pages: 16-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590404
[Presentation] αガラクトシルセラミド感作マウスのエンドトキシン誘発肺傷害のメカニズム-肺NKT細胞の関与-2010
- Author(s)
  横地高志
- Organizer
  毒素シンポジウム
- Place of Presentation
  長浜
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-22590408

1. KATO Yutaka (40267985)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. SUGIYAMA Tsuyoshi (70268001)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 深田允子 (70065548)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HIRAYAMA Mikio (30181192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KUBOTA Toshihiko (70092781)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TANIGUCHI Keiji (50029063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAKANO Masayasu (70048958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HONDA Takeshi (60029808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKEDA Yoshifumi (30029772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MITUYAMA Masao (10117260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NODA Masatoshi (60164703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. IHO Sumiko (80151653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. IWASAKI Hiromichi (10242588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 張月華 (80247717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 中村信一 (90019620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 木下タロウ (10153165)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 小出直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

YOKOCHI Takashi 横地 高志

Research Projects

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Co-Researchers

Crosstalk between pifitlin-a and LPS-mediated inflammatory responsePrincipal Investigator

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Role of tumor-suppressive genes on LPS-induced inflammatory responsePrincipal Investigator

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Establishment of a new experimental model for human septic shockPrincipal Investigator

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The mechanism of the inhibitory action of lipopolysaccharide on anti-cancer drug-induced cell injuryPrincipal Investigator

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Effect of activated protein C on LPS-induced nitric oxide productionPrincipal Investigator

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Identification of immunostimulatory CpG DNA and its activation mechanism in human immune-conmpetent cells

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BMK1は細菌内毒素によるBリンパ球活性化を制御する

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The mechanism of endotoxin-induced vascular endothelial injuryPrincipal Investigator

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THE ROLE OF STRESS PROTEINS IN ENDOTOXIN-INDUCED HEPATIC INJURYPrincipal Investigator

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実験的エンドトキシンショックにおけるアポトーシスの関与Principal Investigator

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細菌内毒素投与による熱ショック蛋白誘導機序Principal Investigator

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肺炎桿菌リポ多糖体の強力な補体活性化能におけるマンナン結合蛋白の役割Principal Investigator

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エンドトキシン投与によるマウス胸腺におけるアポトージスPrincipal Investigator

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YOKOCHI Takashi 横地高志

[Journal Article] Lipopolysaccharide downregulates the expression of p53 through activation of MDM2　and enhances activation of nuclear factor-kappa B2015