Ohura Kiyoshi 大浦清

… Alternative Names

大浦清オオウラキヨシ

OHURA Kiyoshi 大浦清

Less

Researcher Number	20131378
Other IDs
External Links
Affiliation (Current)	2025: 太成学院大学, 看護学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2022: 太成学院大学, 看護学部, 教授 2019: 太成学院大学, 看護学部, 教授 2007 – 2008: Osaka Dental University, 歯学部, 教授 1998 – 2005: 大阪歯科大学, 歯学部, 教授 2000: Osaka Dental University, Professor, 教授 … More 1992 – 1995: 大阪歯科大学, 歯学部, 教授 1989 – 1990: 大阪歯科大学, 歯学部, 助教授 1987 – 1988: 大阪歯科大学, 歯学部, 講師 Less
Review Section/Research Field	Principal Investigator Functional basic dentistry / Functional basic dentistry / Basic Section 57030:Conservative dentistry-related / 病態科学系歯学(含放射線系歯学) Except Principal Investigator Functional basic dentistry / Pathobiological dentistry/Dental radiology / 病態科学系歯学(含放射線系歯学)
Keywords	Principal Investigator マクロファージ / inflammation / phagocytosis / chemotaxis / 貧食能 / 貪食能 / 遊走能 / ラット / LPS / differentiation … More / cytokine / ATP / adenosine / A2a adenosine receptor / PPARγ / macrophages / 歯周病 / rat / leukocyte / gingivitis / diabetes mellitus / 歯周炎 / 白血球 / 歯肉炎 / 糖尿病 / 炎症 / 骨形成因子(BMP) / 歯槽骨再生 / 歯周組織 / BMP-2 / プラスミドベクター / 遺伝子治療 / 再生 / 歯槽骨 / Toll like receptor / toll like receptor / prostaglandins / nuclear transcription factor / natural immunity / プロスタグランジン類 / 核内転写制御因子 / 自然免疫 / hydrogen peroxide / adhesion / superoxide / neutrophils / new quinolones / 過酸化水素産生能 / 接着能 / スーパーオキサイド産生能 / 好中球 / ニューキノロン薬 / macrophage / periodontal disease / 白血病 / insulin / bactericidal activity / インスリン / 殺菌能 / アデノシン / TNFα / 一酸化窒素 / Dilazep / RT-PCR / 遺伝子発現 / ライブイメージング / アデノシン受容体 / 歯科薬理学 … More Except Principal Investigator CD14 / LPS / 白血球 / ラット / 貧食能 / 貪食能 / 遊走能 / odontoma / PARP1 / TLR4 / Gingivitis / 歯周疾患 / 糖尿病 / Phagocytosis / Chemotaxis / Leukocytes / 活性酸素 / Rats / Diabetes mellitus / 歯肉炎 / ghost cell / ameloblast / odontoblast / differentiation / ノックアウトマウス / Parp-1 / 遺伝子操作 / 幻影細胞 / エナメル芽細胞 / 象牙芽細胞 / 細胞分化 / 歯牙腫 / Gingival Fibroblasts / Periodontal Disease / 歯肉線維芽細胞 / 歯周病 / Interleukin / Cytokine / Periodontal disease / インターロイキン / サイトカイン / Leukocyte / Insulin / Streptozotocin / Diabetes / インスリン / ストレプトゾトシン / antibiotic / phagocytosis / chemotaxis / rat / macrophage / leukocyte / chemotherapeutic agent / マクロファージ / 化学療法薬 / Active oxygens / Human / Rat / Local anesthetic / ヒト / 局所麻酔薬 Less

Construction of low invasive therapy for alveolar bone regeneration in clinical usePrincipal Investigator
- Principal Investigator
  
  Ohura Kiyoshi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Taisei Gakuin University
Differentiation of the expression of adenosine receptor affect LPS-induced cytokine production by leukocytesPrincipal Investigator
- Principal Investigator
  
  OHURA Kiyoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka Dental University
Evaluation of a mouse odontoma model and elucidation of the developmental mechanisms of odontoma
- Principal Investigator
  
  NOZAKI Tadashige
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Osaka Dental University
Comparative studies of the effect of adenosine and ATP affect LPS induced inflammationPrincipal Investigator
- Principal Investigator
  
  OHURA Kiyoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka Dental University
Crosstalk between transcription factors responsive to LPS and anti-inflammatory agentsPrincipal Investigator
- Principal Investigator
  
  OHURA Kiyoshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka Dental University
The Heterogeneous Analysis on Periodontopathic LPS Receptor on Gingival Cells
- Principal Investigator
  
  WANG Pao-li
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
  Osaka Dental University
The effect of LPS receptor antibody on experimental periodontitis in mice
- Principal Investigator
  
  OH Hourei
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  OSAKA DENTAL UNIVERSITY
Fundamental research of the effect of a variety of chemotherapeutics on leukocyte functionsPrincipal Investigator
- Principal Investigator
  
  OHURA Kiyoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka Dental University
Effect of insulin on naturally occurring gingivitis rats with diabetes
- Principal Investigator
  
  SHINOHARA Mitsuko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Osaka Dental University
Studies on leukocyte function of periodontal desease and diabetes mellitusPrincipal Investigator
- Principal Investigator
  
  OHURA Kiyoshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Osaka Dental University
Effect of chemotherapeutic agent on leukocyte function
- Principal Investigator
  
  SHINOHARA Mitsuko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka Dental University
The effect of diabetes mellitus on periodontitisPrincipal Investigator
- Principal Investigator
  
  OHURA Kiyoshi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka Dental University
Effect of Local Anesthetics on Leukocyte Function
- Principal Investigator
  
  MORI Masakazu
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka Dental University
Superoxide production by leukocytes from streptozotocin induced diabetic rats and naturally occurring gingivitis rats.
- Principal Investigator
  
  MORI Masakazu
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka Dental University

All 2022 2021 2008 2007 2006 2005 2004 2003

All Journal Article Presentation

[Journal Article] Periodontal Tissue as a Biomaterial for Hard-Tissue Regeneration following bmp-2 Gene Transfer2022
- Author(s)
  Kawai Mariko Yamamoto、Ozasa Ryosuke、Ishimoto Takuya、Nakano Takayoshi、Yamamoto Hiromitsu、Kashiwagi Marina、Yamanaka Shigeki、Nakao Kazumasa、Maruyama Hiroki、Bessho Kazuhisa、Ohura Kiyoshi
- Journal Title
  
  Materials
  
  Volume: 15 Issue: 3 Pages: 993-993
- DOI
  10.3390/ma15030993
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15048, KAKENHI-PROJECT-19K10122, KAKENHI-PROJECT-18H05254, KAKENHI-PROJECT-19H00827, KAKENHI-PROJECT-17K11900
[Journal Article] Expression of PARP1 in odontoma2006
- Author(s)
  Nozaki, T., Watanabe, M., Morita, J., Ohura, K., Kusama, K.
- Journal Title
  
  J.Meikai Univ.Sch. of Dent. 35(1)(in press)
- NAID
  40015368595
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390572
[Journal Article] Differentiation of rat dental pulp-derived cells into an osteoblastic lineage2005
- Author(s)
  Nozaki, T., Takeyasu, M., Hirao, A., Shinohara, M., Daito, M., Ohura, K.
- Journal Title
  
  Oral Sci.Int. 2(2)
  
  Pages: 118-125
- NAID
  10020401693
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390572
[Journal Article] 15-Deoxy-Δ^<12,14>-prostaglandin J_2 and its precursors target phosphoinositide 3-kinase and p38 MAPK to accelerate proliferation in human T cell leukemia cell line Molt-4F.2004
- Author(s)
  Azuma Y, Watanabe K, Date M, Shirasu S, Daito M, Ohura K
- Journal Title
  
  Journal of Oral Biosciences 46(1)
  
  Pages: 37-46
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591987
[Journal Article] In vitro osteogenic differentiation potential of dental pulp stem cells2004
- Author(s)
  Takeyasu, M., Nozaki, T., Watanabe, M., Shinohara, M., Morita, J., Hidaka, A., Iwamoto, K., Takahashi, T., Nagata, S., Daito M., Ohura, K.
- Journal Title
  
  J.Oral Tissue Engin. 2(1)
  
  Pages: 25-30
- NAID
  110006164156
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390572
[Journal Article] Comparative studies of effects of adenosine and ATP on all-trans retinoic acid,1,25-dihydroxy-vitamin D_3 and phorbol 12-myristate 13-acetate-induced differentiation in U937 human leulemia cells.2004
- Author(s)
  Azuma Y, Watanabe K, Shirasu S, Daito M, Ohura K
- Journal Title
  
  Journal of Oral Biosciences 46(1)
  
  Pages: 11-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591987
[Journal Article] Induction of proliferation by 15-Deoxy-Δ^<12,14>prostaglandin J_2 and the precursors in monocytic leukemia U937.2004
- Author(s)
  Azuma Y, Watanabe K, Date M, Daito M, Ohura K
- Journal Title
  
  Pharmacology 71
  
  Pages: 181-191
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591987
[Journal Article] Possible involvement of p38 in mechanisms underlying acceleration of proliferation by 15-Deoxy-Δ^<12,14> prostaglandin J_2 and the precursors in leukemia cell line THP-1.2004
- Author(s)
  Azuma Y, Watanabe K, Date M, Daito M, Ohura K
- Journal Title
  
  Journal of Pharmacological Sciences 94
  
  Pages: 261-270
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591987
[Journal Article] Apoptosis in human oral squamous cell carcinomas is induced by 15-Deoxy-Δ^<12,14>-prostaglandin J_2 but not by troglitazone.2003
- Author(s)
  Fukuchi K, Date M, Azuma Y, Shinohara M, Takahashi H, Ohura K
- Journal Title
  
  Journal of Dental Research 82
  
  Pages: 802-806
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591987
[Journal Article] Induction of differentiation in leukemia THP-1 cells treated with adenosine and ATP.2003
- Author(s)
  Azuma Y, Watanabe K, Shirasu S, Daito M, Ohura K
- Journal Title
  
  Oral Therapeutics and Pharmacology 22
  
  Pages: 127-135
- NAID
  10016242383
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591987
[Journal Article] Possible mechanisms underlying acceleration of proliferation by 15-deoxy^<-12,14-> prostaglandin J_2 and the precursors in human T acute lymphoblastic leukemia cell line CCRF-CEM.2003
- Author(s)
  Azuma Y, Watanabe K, Date M, Shirasu S, Daito M, Ohura K
- Journal Title
  
  Oral Therapeutics and Pharmacology 22
  
  Pages: 160-168
- NAID
  10016242484
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591987
[Journal Article] Adenosine and ATP affect LPS-induced cytokine production by macrophages.2003
- Author(s)
  Watanabe K, Azuma Y, Shirasu S, Daito M, Ohura K
- Journal Title
  
  Oral Therapeutics and Pharmacology 22
  
  Pages: 105-110
- NAID
  10016242298
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591987
[Journal Article] 15-Deoxy-Δ^<12,14> prostaglandin J_2,a ligand for peroxisome proliferators-activated receptor-γ, induces apoptosis in human hepatoma cells.2003
- Author(s)
  Date M, Fukuchi K, Morita S, Takahashi H, Ohura K
- Journal Title
  
  Liver International 23
  
  Pages: 460-466
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591987
[Journal Article] Altertion of the expression of A2a adenosine receptor and Toll-like receptor 4 in macrophage cell lines.2003
- Author(s)
  Watanabe K, Azuma Y, Shirasu S, Daito M, Ohura K
- Journal Title
  
  Journal of Oral Biology 45
  
  Pages: 437-444
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591987
[Presentation] 歯槽骨再生治療薬としての骨形成因子遺伝子発現プラスミッドの可能性について2022
- Author(s)
  山本まりこ、大浦　清
- Organizer
  第141回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-19K10122
[Presentation] 歯槽骨再生遺伝子治療モデルにおける骨形態計測学的解析の有効性について2021
- Author(s)
  山本まりこ , 大浦清
- Organizer
  第29回硬組織再生生物学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10122
[Presentation] Dilazep decrease LPS-induced nitric oxide and TNFα synthesis in RAW2642008
- Author(s)
  Nakatsuka R, Nozaki T, Ohura K
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2008-03-18
- Data Source
  KAKENHI-PROJECT-19592164
[Presentation] J Dilazep decrease LPS-induced nitric oxide and TNFα synthesis in RAW2642008
- Author(s)
  Ryusuke Nakatsuka, Tadashige Nozaki, Kiyoshi Ohura
- Organizer
  J Pharmacological Science, Vol.106, Suppl.I, 198P
- Data Source
  KAKENHI-PROJECT-19592164
[Presentation] 乳歯歯髄由来線維芽細胞のMMP-2産生におけるPI3-Kの関与について2008
- Author(s)
  渡邊京子, 白数慎也, 大東希好, 大浦清, 大東道治.
- Organizer
  第28回日本歯科薬物療法学会総会・学術大会
- Place of Presentation
  文京シビックホール(東京都)
- Year and Date
  2008-06-28
- Data Source
  KAKENHI-PROJECT-19592164
[Presentation] 乳歯歯髄由来線維芽細胞のMMP-2産生におけるPI3-Kの関与について2008
- Author(s)
  渡邊京子,白数慎也,大東希好,大浦清,大東道治
- Organizer
  歯薬療法, Vol.27, N0.3 , 188
- Data Source
  KAKENHI-PROJECT-19592164
[Presentation] LPS刺激乳歯歯髄由来線維芽細胞におけるMMP-2産生増強2007
- Author(s)
  渡邊京子,白数慎也,大東希好,大浦清,大東道治
- Organizer
  J Oral Bioscience, Vol.49, Suppl., 179
- Data Source
  KAKENHI-PROJECT-19592164

1. SHINOHARA Mitsuko (40067187)

# of Collaborated Projects: 9 results

# of Collaborated Products: 1 results
2. AZUMA Yasutaka (50298816)

# of Collaborated Projects: 6 results

# of Collaborated Products: 9 results
3. OGATA Keigo (30214000)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. OH Hourei (20213613)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MORI Masakazu (20066963)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MORI Ryoichi (30509310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TACHI Yoichi (90309188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAITO Makoto (80329474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MIYAZAWA Yoshiko (10200164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NOZAKI Tadashige (90281683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. FUJIMOTO Heizo (20190077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 山本まりこ (40379839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 河井まりこ

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 小笹良輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohura Kiyoshi 大浦 清

大浦 清 オオウラ キヨシ

OHURA Kiyoshi 大浦 清

Research Projects

Research Products

Co-Researchers

Construction of low invasive therapy for alveolar bone regeneration in clinical usePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Differentiation of the expression of adenosine receptor affect LPS-induced cytokine production by leukocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of a mouse odontoma model and elucidation of the developmental mechanisms of odontoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comparative studies of the effect of adenosine and ATP affect LPS induced inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Crosstalk between transcription factors responsive to LPS and anti-inflammatory agentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Heterogeneous Analysis on Periodontopathic LPS Receptor on Gingival Cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of LPS receptor antibody on experimental periodontitis in mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Fundamental research of the effect of a variety of chemotherapeutics on leukocyte functionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of insulin on naturally occurring gingivitis rats with diabetes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on leukocyte function of periodontal desease and diabetes mellitusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of chemotherapeutic agent on leukocyte function

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of diabetes mellitus on periodontitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of Local Anesthetics on Leukocyte Function

Principal Investigator

Ohura Kiyoshi 大浦清

大浦清オオウラキヨシ

OHURA Kiyoshi 大浦清