TSUCHIDA Shigeki 土田成紀

… Alternative Names

土田成紀ツチダシゲキ

Less

Researcher Number	20142862
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2017: 弘前大学, 医学研究科, 客員研究員 2016: 弘前大学, 医学研究科, 教授 2012 – 2015: 弘前大学, 医学(系)研究科(研究院), 教授 2014: 弘前大学, 医学研究科, 教授 2002 – 2004: 弘前大学, 医学部, 教授 … More 1993 – 1994: Hirosaki University School of Medicine, Second Depatment of Biochemistry, Professor, 医学部, 教授 1991 – 1992: 弘前大学, 医学部, 講師 1986: 弘前大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Experimental pathology Except Principal Investigator Laboratory animal science / Laboratory animal science
Keywords	Principal Investigator Heme / Glutathione / Active oxygen species / Guanylate cyclase / Nitroglycerin / Nitric oxide / Endothelium-derived relaxing factor / Glutathione S-transferase / グアニル酸シクラ-ゼ / グルタチオンSートランスフェラ-ゼ … More / ポルフィリン / ヘム / グルタチオン / 活性酸素 / グアニル酸シクラーゼ / ニトログリセリン / 一酸化窒素 / 血管弛緩因子 / グルタチオンS-トランスフェラーゼ / hypoxia-inducible factor / 血管内皮細胞増殖因子 / カルボニル還元酵素 / 転移 / 卵巣がん … More Except Principal Investigator グルタチオン S-トランスフェラーゼ / 胸腺 / 弘前ヘアレスラット (HHR) / SDラット (SDR) / クロマチン構造 / Gata3遺伝子プロモーター / Fog1 / ヘルパーT細胞の分化 / Gata3 / NF-kB / Dec1 / Cryab / Egr1 / レチノイン酸受容体 / 胸腺DP細胞 / 脾臓 / レチノイン酸 / 分化 / CD4+T細胞 / Questionnaire / Epidemiology / Glutathione S-transferase / Dietary style / Oncogene / Colorectal cancer / Gastric cancer / アメリカ / 日本 / 環境因子 / 消化器癌 / グルタチオンS-トランスフェラーゼ / アンケート / 疫学 / 食生活 / 癌遺伝子 / 大腸癌 / 胃癌 / 肝化学発癌 / 前癌病変 / 胎盤型 / アイソザイム / 腫瘍マーカー / ケモカイン / 樹状細胞 / ビタミンA / 胸腺樹状細胞 / ヘルパーT細胞 / 弘前へアレスラット / Ly49s3遺伝子 / B1-B細胞 / 制御性T細胞 / 弘前ヘアレスラット Less

Analysis of importance of thymic vitamin A to helper T cell differentiation using a newly established animal model
- Principal Investigator
  
  Yamada Toshiyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Nihon Pharmaceutical University
  Hirosaki University
Establishment of a new model rat for immunological diseases deleting the Ly49 gene regulating immune reactions
- Principal Investigator
  
  YAMADA Toshiyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Hirosaki University
カルボニル還元酵素による卵巣がん転移抑制の分子機構Principal Investigator
- Principal Investigator
  
  土田成紀
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Hirosaki University
Comparative study on cancers between Japan and U.S.A.
- Principal Investigator
  
  YOSHIDA Yutaka
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Hirosaki University
Metabolism of Endothelium-Derived Relaxing Factor, Nitric Oxide, by Glutathione S-TransferasesPrincipal Investigator
- Principal Investigator
  
  TSUCHIDA Shigeki
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  HIROSAKI UNIVERSITY
新腫瘍マーカーグルタチオンS-転移酵素P型の基礎的,臨床的研究
- Principal Investigator
  
  佐藤清美
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Hirosaki University

All 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Involvement of Clustered Genes in Mammalian Functions: Their Relation in a Rat Mutant Strain.2017
- Author(s)
  Naoki Nanashima, Toshiyuki Yamada, Takeshi Shimizu, Shigeki Tsuchida.
- Journal Title
  
  Journal of molecular evolution
  
  Volume: 22 Issue: 4 Pages: 1-3
- DOI
  10.1007/s00239-017-9788-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00844, KAKENHI-PROJECT-15K06796
[Journal Article] Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness.2017
- Author(s)
  Nanashima N, Horie K, Yamada T, Shimizu T, Tsuchida S
- Journal Title
  
  Oncol. Rep.
  
  Volume: 37 Pages: 2964-2970
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06796
[Journal Article] The Hirosaki small-eye rat: A novel recessive model animal of lens and retinal degeneration with loss of βA3/A1-crystallin2016
- Author(s)
  Yamada T、Tsuchida S
- Journal Title
  
  Precision Medicine
  
  Volume: 2 Pages: 1-5
- DOI
  10.14800/pm.1140
- Data Source
  KAKENHI-PROJECT-15K06796
[Journal Article] Fatty acid synthase-positive hepatocytes and subsequent steatosis in rat livers by irinotecan2015
- Author(s)
  Sawano T, Shimizu T, Yamada T, Nanashima N, Miura T, Morohashi S, Kudo D, Hui F-M, Kijima H, Hakamada K, Tsuchida S
- Journal Title
  
  Oncology Reports
  
  Volume: 33 Pages: 2151-2160
- DOI
  10.3892/or.2015.3814
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500484, KAKENHI-PROJECT-24591990, KAKENHI-PROJECT-25861148
[Journal Article] Ly49 and C-type lectin receptors on dendritic cells regulate T-cell differentiation as co-stimulatory molecules2014
- Author(s)
  Yamada T, Tsuchida S
- Journal Title
  
  Receptors & Clinical Investigation
  
  Volume: 1 Pages: 101-111
- DOI
  10.14800/rci.98
- Data Source
  KAKENHI-PROJECT-24500484
[Journal Article] Lectin-like receptor Ly49s3 on dendritic cells contributes to the differentiation of regulatory T cells in the rat thymus2013
- Author(s)
  Yamada T, Nanashima N, Akita M, Shimizu T, Miura T, Yamana D, Sawano T, Sakurai T, Tsuchida S
- Journal Title
  
  Journal of Immunology
  
  Volume: 191 Issue: 7 Pages: 3799-3809
- DOI
  10.4049/jimmunol.1203511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500484, KAKENHI-PROJECT-24500798, KAKENHI-PROJECT-25640058
[Presentation] 非遺伝毒性発がん剤投与のラット肝マクロファージにおけるphospholipase A2と転写因子C/EBPβの発現2017
- Author(s)
  清水武史、七島直樹、山田俊幸、土田成紀
- Organizer
  第40回日本分子生物学会年会、第90回日本生化学会大会、合同年会
- Data Source
  KAKENHI-PROJECT-15K06796
[Presentation] 濾胞性ヘルパーT細胞分化への胸腺でのレチノイン酸によるGata3誘導と脾臓でのFog1誘導関与2017
- Author(s)
  山田俊幸、清水武史、土田成紀
- Organizer
  第40回日本分子生物学会年会、第90回日本生化学会大会、合同年会
- Data Source
  KAKENHI-PROJECT-15K06796
[Presentation] ラット脾臓でのヘルパーT細胞分化における転写共役因子Fog1の重要性2016
- Author(s)
  山田俊幸、七島直樹、清水武史、土田成紀
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K06796
[Presentation] ヘルパーT細胞の分化と機能におよぼすレチノイン酸の影響：弘前ヘアレスラットを用いた解析2015
- Author(s)
  山田俊幸、七島直樹、清水武史、土田成紀
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸ポートピアホテル（兵庫県、神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06796
[Presentation] 弘前ヘアレスラット脾臓での濾胞性ヘルパーT細胞の分化異常と胸腺内CD4+CD8+細胞でのレチノイン酸結合タンパク質遺伝子および受容体遺伝子の発現異常2014
- Author(s)
  山田俊幸、七島直樹、清水武史、土田成紀
- Organizer
  第80回日本生化学会東北支部会例会
- Place of Presentation
  秋田
- Year and Date
  2014-05-10
- Data Source
  KAKENHI-PROJECT-24500484
[Presentation] CD4陽性T細胞からのNK細胞受容体遺伝子Klra17の発現消失と濾胞性ヘルパーT細胞の機能不全2013
- Author(s)
  山田俊幸、七島直樹、清水武史、澤野武行、土田成紀
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24500484
[Presentation] 発がん抵抗性ラットでの制御性T細胞の分化異常は胸腺内樹状細胞とT細胞で発現するLy49遺伝子の欠損による2012
- Author(s)
  山田俊幸、七島直樹、清水武史、澤野武行、土田成紀
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24500484
[Presentation] ラット胸腺内樹状細胞からのLy49ファミリー遺伝子の発現消失による制御性T細胞の分化抑制2012
- Author(s)
  山田俊幸、七島直樹、清水武史、澤野武行、土田成紀
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24500484
[Presentation] ラット胸腺樹状細胞に発現するNK細胞受容体Ly49s3の制御性T細胞分化における役割
- Author(s)
  山田俊幸、七島直樹、清水武史、土田成紀
- Organizer
  第79回　日本生化学会東北支部会例会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24500484
[Presentation] 水晶体の退縮と網膜の剥離を示す劣性遺伝性ラットの樹立と原因遺伝子の解明
- Author(s)
  山田俊幸、七島直樹、清水武史、土田成紀
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24500484

1. YAMADA Toshiyuki (20183981)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
2. HATAYAMA Ichiro (40133871)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. SATOH Kimihiok (70003655)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. YOSHIDA Yutaka (80003375)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAKAJI Shigeyuki (10192220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TSUSHIMA Kenichi (60236875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 早狩誠 (80156421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 佐藤清美 (50006079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 七島直樹 (80333730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. 清水武史 (90374818)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. SCOTT Robert e.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HAMNER James e.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. JOHNSON Leon

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. JOHNSON Leonard r.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. LEONARD R. J

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. ROBERT E. Sc

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. JAMES E. Ham

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. LEONARD R Jo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. ROBEET E Sco

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. JAMES E Hamn

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TSUCHIDA Shigeki 土田 成紀

土田 成紀 ツチダ シゲキ

Research Projects

Research Products

Co-Researchers

Analysis of importance of thymic vitamin A to helper T cell differentiation using a newly established animal model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of a new model rat for immunological diseases deleting the Ly49 gene regulating immune reactions

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

カルボニル還元酵素による卵巣がん転移抑制の分子機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comparative study on cancers between Japan and U.S.A.

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Metabolism of Endothelium-Derived Relaxing Factor, Nitric Oxide, by Glutathione S-TransferasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新腫瘍マーカーグルタチオンS-転移酵素P型の基礎的,臨床的研究

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] Involvement of Clustered Genes in Mammalian Functions: Their Relation in a Rat Mutant Strain.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness.2017

Author(s)

Journal Title

Data Source

[Journal Article] The Hirosaki small-eye rat: A novel recessive model animal of lens and retinal degeneration with loss of βA3/A1-crystallin2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fatty acid synthase-positive hepatocytes and subsequent steatosis in rat livers by irinotecan2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ly49 and C-type lectin receptors on dendritic cells regulate T-cell differentiation as co-stimulatory molecules2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lectin-like receptor Ly49s3 on dendritic cells contributes to the differentiation of regulatory T cells in the rat thymus2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] 非遺伝毒性発がん剤投与のラット肝マクロファージにおけるphospholipase A2と転写因子C/EBPβの発現2017

Author(s)

Organizer

Data Source

[Presentation] 濾胞性ヘルパーT細胞分化への胸腺でのレチノイン酸によるGata3誘導と脾臓でのFog1誘導関与2017

Author(s)

Organizer

Data Source

[Presentation] ラット脾臓でのヘルパーT細胞分化における転写共役因子Fog1の重要性2016

Author(s)

Organizer

Place of Presentation

TSUCHIDA Shigeki 土田成紀

土田成紀ツチダシゲキ