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SHIGEMATSU Kazuto  重松 和人

ORCIDConnect your ORCID iD *help
Researcher Number 20154205
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2002 – 2003: 長崎大学, 大学院・医歯薬学総合研究科, 助教授
1995 – 2001: 長崎大学, 医学部, 助教授
1988 – 1992: 長崎大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Experimental pathology / Human pathology
Except Principal Investigator
Virology / General pharmacology / General surgery / Neurology / Neuroscience in general / Cerebral neurosurgery
Keywords
Principal Investigator
Doppel / Endothelin / osteopontin / ROS / NADH oxidase / cDNA subtraction / protease-resistant / PrP / blood-brain-barrier / プリオン病 … More / mRNA / functional receptor / immunohistochemistry / in situ hybridization / receptor autoradiography / receptor / Immunohistochemistry / 免疫組織化学 / Receptor Autoradiography / Adrenal Tumor / Lung Cancer / Brain Tumor / Receptor / Epidermal Growth Factor / Insulin-Like Growth Factor I / ヒト副腎 / ラット脳 / 定量的receptor autoradigraphy / IGF-I / 成長因子 / インシュリン / レセプタ-・オ-トラジオグラフィ / 副腎腫瘍 / 肺癌 / 脳腫瘍 / 受容体 / 上皮成長因子 / インシュリン様成長因子 / Kidney / 変換抑制因子 / PrPSc / PrPC / tNOX / PrPLP / 異常型プリオン / kidney / endothelial cell / prion disease / glia cell / prioa protein-deficient mice / PrPLP gene / blood-testis-barrier / セルトリ細胞 / PrP遺伝子欠損マウス / 血管内皮細胞 / 脳血液関門 / グリア細胞 / PrP蛋白欠損マウス / PrPLP遺伝子 / Dopple / receptor-autoradiography / endothelin / in situ hybridigation / Computerized Densitometry / Auoradiography / Brain Ischemia / Quantitative Radioimmunohistochemical Method / オ-トラジオグラフィ-法 / radioimmunochemistry / 定量的radioimmunochemistry法 / コンピュ-タ-化電単トメトリ- / オ-トラジオグラフィ / 脳虚血 / エンドセリン / 定量的radioimmunohistochemistry法 … More
Except Principal Investigator
神経細胞死 / プリオン / プリオン病 / プリオン蛋白 / エンドセリン受容体 / vascular endothelial growth factor / MCP-1 / ノックアウトマウス / ペプチド / PRION PROTEIN / 脱髄 / アストロサイト / 遺伝子改変動物 / 軸索 / プルキンエ細胞 / 神経変性 / トランスジェニックマウス / neurotransmitters / receptor autoradiography / endothelin receptors / エンドセリン / Gene-knockout mice / RNA splicing / Neurodegeneration / Prion protein / Prion diseases / ファージデイスプレイ / 生理機能 / 遺伝子ノックアウトマウス / RNAスプライシング / quantitative receptor imaging system / ileus / myenteric plexus / substance P receptors / Hischsprung's disease / ヒルシュスプルング病 / 定量的受容体画像化システム / イレウス / 筋層間神経叢 / サブスタンスP受容体 / 神経伝達物質受容体 / ヒルシュプルング病 / hippocampus CA1 neurons / blood-brain barrier / endothelin receptor / endothelin / microglia / ischemia-related neuronal death / 脳血液関門 / 海馬CAI神経細胞 / vascular endothdial growth factor / 脳血液関門(BBB) / ミクログリア / 虚血性神経細胞死 / PROTEIN-PROTEIN INTERACTION / THERAPEUTICS / PEPTIDES / PRION DISEASES / グリア / ニューロン / 遺伝子改変マウス / ペプチドライブラリ / 発症予防 / ファージディスプレイ / 発症遅延 / 蛋白蛋白相互作用 / liposome / knockout mouse / prion / リポソーム / 遺伝子欠損マウス / DEMYELINATION / NEURODEGENERATION / PURKINJE CELLS / TARGETED MYTAGENESIS / ターゲティングマウス / neurons / central nervous system / receptors / receptor imaging / radioimmunohistochemistry / in situ hybridization / in situバイブリダイゼーション法 / 定量液放射免疫組織化学法 / 神経細胞 / 中枢神経 / 受容体 / 神経伝達物質 / 受容体画像 / 定量的放射免疫組織化学法 / in situハイブリダイゼーション法 / 定量的受容体オートラジオグラフィー法 / human spinal cord / porcine spinal cord / rat brain / chemical cross-linking / 受容体活性部位 / 定量的受容体オ-トラジオグラフ法 / ヒト脊髄 / ブタ脊髄 / ラット脳 / クロスリンキング法 / 受容体オートラジオグラフ法 Less
  • Research Projects

    (13 results)
  • Co-Researchers

    (12 People)
  •  Analysis of Factors To Control The Conversion Of Abnormal Prion Protein From Normal Prion ProteinPrincipal Investigator

    • Principal Investigator
      SHIGEMATU Kazuto
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagasaki University
  •  Identification of expression cells and elucidation of a function for a novel gene encoding a PrP-like protein newly separated and identifiedPrincipal Investigator

    • Principal Investigator
      SHIGEMATSU Kazuto
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagasaki University
  •  Molecular Mechanisms for Purkinje Cell Degeneration and Demyelination in Prion Protein-Deficient Mice.

    • Principal Investigator
      KATAMINE Shigeru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Virology
    • Research Institution
      Nagasaki University
  •  MECHANISMS OF NEUTONAL CELL DEATH IN PRION PROTEIN-LESS MICE

    • Principal Investigator
      KATAMINE Shigeru
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Neuroscience in general
    • Research Institution
      Nagasaki University
  •  Elucidation of the nature of a Creutfeldt-Jakob disease agent using prion protein gene-knockout mice

    • Principal Investigator
      SAKAGUCHI Suehiro
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      NAGASAKI UNIVERSITY
  •  MOLECULAR MECHANISMS FOR PRION PROTEIN CONVERSION AND CELL-TYPES INVOLVED IN THE CONVERSION IN VIVO

    • Principal Investigator
      KATAMINE Shigeru
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      NAGASAKI UNIVERSITY
  •  Microglial activation and blood-brain barrier function in ischemia-related neuronal death

    • Principal Investigator
      NIWA Masami
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      NAGASAKI UNIVERSITY
  •  Comparison of Cells Expressed Between Functional Endothelin Receptor Proteins and Their mRNAs by Quantitative Imazing Analyzer SystemPrincipal Investigator

    • Principal Investigator
      SHIGEMATSU Kazuto
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagasaki University
  •  Receptors for neurotransmitters in Auerbach's plexus of Hirschsprung's disease ; A comparison with animal models

    • Principal Investigator
      KANEMATSU Takashi, 大野 康治
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      NAGASAKI UNIVERSITY
  •  A new research technique with the computerized radioluminographic imaging-plate system for receptors of neurotransmitters

    • Principal Investigator
      NIWA Masami
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      NAGASAKI UNIVERSITY
  •  Analysis for specific binding sites of endothelins

    • Principal Investigator
      NIWA Masami
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Department of Pharmacology 2, Nagasaki University School of Medicine
  •  Quantitative Radioimmunohistochemical Method to Measure the Tissue Content of Specific MoleculesPrincipal Investigator

    • Principal Investigator
      SHIGEMATSU Kazuto
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagasaki University
  •  Research for Growth Factor Receptors in Human Tumor TissuesPrincipal Investigator

    • Principal Investigator
      SHIGEMATSU Kazuto
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Nagasaki University
  • 1.  NIWA Masami (20136641)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  KATAOKA Yasufumi (70136513)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  SAKAGUCHI Suehiro (60274635)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  TANIYAMA Kohtaro (70030898)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  KATAMINE Shigeru (40161062)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  SHIRABE Susumu (40264220)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  KANEMATSU Takashi (40128004)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  YAMASHITA Kimihiro (50192399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  NAGAYAMA Yuji (30274632)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KURIHARA Masaki (50161766)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  大野 康治 (70274644)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  DERI Maria.A
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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