TAKEUCHI Masayoshi 竹内正義

… Alternative Names

竹内正義タケウチマサヨシ

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Researcher Number	20154982
Other IDs
External Links
Affiliation (Current)	2025: 金沢医科大学, 総合医学研究所, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 金沢医科大学, 総合医学研究所, 教授 2011 – 2019: 金沢医科大学, 総合医学研究所, 教授 2010: 北陸大学, 薬学部, 教授 2007 – 2008: Hokuriku University, 薬学部, 教授 2000 – 2003: Department of Biochemistry, Faculty of Pharmaceutical Science, Hokuriku University, Assistant Professor, 薬学部, 講師
Review Section/Research Field	Principal Investigator Eating habits / Eating habits, studies on eating habits / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Psychiatric science Except Principal Investigator Applied pharmacology / Eating habits / Functional biochemistry / Psychiatric science
Keywords	Principal Investigator 生活習慣病 / 終末糖化産物 / Toxic AGEs (TAGE) / 食生活 / TAGE / 飲食品 / 清涼飲料水 / メイラード反応 / TAGE化蛋白質 / TAGE修飾蛋白質 … More / 細胞障害 / 現代の食習慣 / TAGE原因説 / 毒性終末糖化産物 / 飲食物 / 健康寿命延伸 / 生活習慣病予防 / HFCS / 健康寿命 / 食生活習慣 / Toxic AGEs / neurodegenerative diseases / Alzheimer's disease / Glycation / AGE-2 derived Aβ (1-40) / Aβ (1-40) / AGE-2 structure / Advanced glycation end-product / Advanced Glycation End-product / 神経変性疾患 / アルツハイマー病 / グリケーション / AGE-2化Aβ(1→40) / Aβ(1→40) / AGE-2構造体 / Advanced Glycation End-products / NASH / NAFLD / 食習慣 / 毒性AGEs / 加工食品 / 果糖 / 食事性AGEs / 食後高血糖 / RAGE / Toxic AGEs(TAGE) / 飲食料品 / 健康食品 / 糖尿病 / AGEs … More Except Principal Investigator AGE / 終末糖化産物 / life-style related diseases / esRAGE / VCAM-1 / MAP kinase / RAGE / advanced glycation endproducts / 質量分析法 / 糖尿病性腎症 / バイオマーカー / プロテオーム解析 / 一本鎖抗体 / 食習慣 / 電子顕微鏡 / オートファジー / NASH / 小胞体ストレス / 初代培養肝細胞 / 初代培養心筋細胞 / グリセルアルデヒド / 終末糖化タンパク / RAGE knockout / diabetic angiopath / NF-κB / diabetic angiopathy / Diabetes mellitus / Alzheimer disease / 病理学 / 神経変性疾患 / 終末糖化物質 / 糖尿病 / アルツハイマー病 Less

生活習慣病の新規概念「毒性終末糖化産物（Toxic AGEs）原因説」の確立Principal Investigator
- Principal Investigator
  
  竹内正義
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Kanazawa Medical University
Developments of functional single-chain antibodies and unraveling of mechanisms of diseases associated with advanced glycation end-products
- Principal Investigator
  
  MORIOKA Hiroshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kumamoto University
Generation and accumulation of intracellular toxic advanced glycation end-products due to modern dietary habits and elucidation of relevant cytotoxic mechanismsPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Masayoshi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Eating habits
- Research Institution
  Kanazawa Medical University
Excessive ingestion of sugar causes the abnomality of endoplasmic reticulum, resulting in providing for NASH
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Eating habits
- Research Institution
  Kanazawa Medical University
Association between characteristics of current diet and onset/deterioration of non-alcoholic fatty liver diseasePrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Masayoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits
- Research Institution
  Kanazawa Medical University
1nvolvement of hyperglycemiaand dietary AGEs inthe prevention of life style-related diseasePrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Masayoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Kanazawa Medical University
  Hokuriku University
Involvement of dietary AGEs in the life style-related diseasePrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Masayoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Hokuriku University
Study on the mechanism of vascular injury by novel species of advanced glycation endoproducts
- Principal Investigator
  
  WATANABE Takuo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  KANAZAWA UNIVERSITY
The study for neurotoxicity of advanced glycation end-products (the structural epitope AGE-2) in neurodegenerative processesPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Masayoshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Hokuriku University
Neurotoxicity of advanced glycation end products in Alzheimer disease
- Principal Investigator
  
  MAKITA Zenji
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Psychiatric science
- Research Institution
  Kurume University School of Medicine
  Hokkaido University

[Book] 循環器病・介護予防に向けた未病ガイドライン-その根拠となる論文集-2016
- Author(s)
  竹内正義
- Total Pages
  11
- Publisher
  未病息災推進協議会発行
- Data Source
  KAKENHI-PROJECT-16H01811
[Book] アンチエイジングのための100の質問2014
- Author(s)
  竹内正義
- Total Pages
  2
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-25282029
[Book] アンチエイジングのための100の質問2014
- Author(s)
  逆井（坂井）亜紀子、竹内正義
- Total Pages
  2
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-25282029
[Book] アンチエイジングのための100の質問2014
- Author(s)
  高田尊信、竹内正義
- Total Pages
  2
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-25282029
[Book] AGEsと老化−糖化制御からみたウエルエイジング−（太田博明監修）2013
- Author(s)
  竹内　正義
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-22300264
[Book] 食事性AGEsと未病2008
- Author(s)
  竹内正義
- Total Pages
  6
- Publisher
  (財)博慈会老人病研究所
- Data Source
  KAKENHI-PROJECT-19300254
[Book] 食事性AGEs と未病.未病と抗老化2008
- Author(s)
  竹内正義ほか(4)
- Data Source
  KAKENHI-PROJECT-19300254
[Book] YAKUGAKU ZASSHI:生活習慣病における終末糖化産物(AGEs)の関与とその阻止2007
- Author(s)
  竹内正義
- Total Pages
  4
- Publisher
  (社)日本薬学会
- Data Source
  KAKENHI-PROJECT-19300254
[Book] 生体の科学:特集「グリケーション(糖化)」:AGEs(終末糖化産物)にはどんなものがあるか-毒性終末糖化産物仮説2007
- Author(s)
  竹内正義
- Total Pages
  11
- Publisher
  (財)金原一郎記念医学医療振興財団/医学書院
- Data Source
  KAKENHI-PROJECT-19300254
[Book] 生活習慣病における終末糖化産物(AGEs)の関与とその阻止. YAKUGAKU ZASSHI 127 Suppl.2007
- Author(s)
  竹内正義、佐藤隆、山岸昌一
- Data Source
  KAKENHI-PROJECT-19300254
[Book] AGEs(終末糖化産物)にはどんなものがあるか -毒性終末糖化産物仮説. 生体の科学2007
- Author(s)
  竹内正義、瀧野純一、佐藤隆ほか (3)
- Data Source
  KAKENHI-PROJECT-19300254
[Journal Article] Toxic advanced glycation end-products (TAGE) are major structures of cytotoxic AGEs derived from glyceraldehyde2024
- Author(s)
  Takeuchi Masayoshi、Suzuki Hirokazu、Takeda Kenji、Sakai-Sakasai Akiko
- Journal Title
  
  Medical Hypotheses
  
  Volume: 183 Pages: 111248-111248
- DOI
  10.1016/j.mehy.2023.111248
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11583, KAKENHI-PROJECT-21H04865
[Journal Article] Effect of Anagliptin on Vascular Injury in the Femoral Artery of Type 2 Diabetic Rats2024
- Author(s)
  Noda Masato、Kikuchi Chigusa、Hori Eisei、Iwao Takahiro、Nagami Chie、Takeuchi Masayoshi、Matsunaga Tamihide
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 47 Issue: 1 Pages: 204-212
- DOI
  10.1248/bpb.b23-00706
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2024-01-19
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04865
[Journal Article] Structures of Toxic Advanced Glycation End-Products Derived from Glyceraldehyde, A Sugar Metabolite2024
- Author(s)
  Sakai-Sakasai Akiko、Takeda Kenji、Suzuki Hirokazu、Takeuchi Masayoshi
- Journal Title
  
  Biomolecules
  
  Volume: 14 Issue: 2 Pages: 202-202
- DOI
  10.3390/biom14020202
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08410, KAKENHI-PROJECT-21K11583, KAKENHI-PROJECT-21H04865
[Journal Article] Toxic AGEs (TAGE)と健康：I. 細胞障害因子としてのTAGE.2023
- Author(s)
  坂井(逆井)亜紀子、竹田健史、竹内正義
- Journal Title
  
  金沢医科大学雑誌
  
  Volume: 48 Pages: 1-11
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04865
[Journal Article] Prediagnostic serum glyceraldehyde-derived advanced glycation end products and mortality among colorectal cancer patients2023
- Author(s)
  Mao Ziling、Baker Jacqueline Roshelli、Takeuchi Masayoshi、Hyogo Hideyuki、他32名
- Journal Title
  
  International Journal of Cancer
  
  Volume: 152 Issue: 11 Pages: 2257-2268
- DOI
  10.1002/ijc.34449
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04865
[Journal Article] A Novel Approach: Investigating the Intracellular Clearance Mechanism of Glyceraldehyde-Derived Advanced Glycation End-Products Using the Artificial Checkpoint Kinase 1 d270KD Mutant as a Substrate Model2023
- Author(s)
  Takeda Kenji、Sakai-Sakasai Akiko、Kajinami Kouji、Takeuchi Masayoshi
- Journal Title
  
  Cells
  
  Volume: 12 Issue: 24 Pages: 2838-2838
- DOI
  10.3390/cells12242838
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08139, KAKENHI-PROJECT-20K08410, KAKENHI-PROJECT-21K11583, KAKENHI-PROJECT-21H04865
[Journal Article] Toxic AGEs (TAGE)と健康：II. 生活習慣病予測マーカーとしてのTAGE.2023
- Author(s)
  竹内正義、竹田健史、坂井(逆井)亜紀子
- Journal Title
  
  金沢医科大学雑誌
  
  Volume: 48 Pages: 12-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04865
[Journal Article] Involvement of Intracellular TAGE and the TAGE?RAGE?ROS Axis in the Onset and Progression of NAFLD/NASH2023
- Author(s)
  Sakasai-Sakai Akiko、Takeda Kenji、Takeuchi Masayoshi
- Journal Title
  
  Antioxidants
  
  Volume: 12 Issue: 3 Pages: 748-748
- DOI
  10.3390/antiox12030748
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11583, KAKENHI-PROJECT-21H04865
[Journal Article] Glyceraldehyde-derived advanced glycation end-products are associated with the severity of cardiac function and heart failure in patients with diabetic cardiomyopathy2022
- Author(s)
  Yasuda Y, Aoki H, Wakasa M, Fujita W, Kawai Y, Kajinami K
- Journal Title
  
  Scand Cardiovasc J
  
  Volume: 56 Issue: 1 Pages: 208-216
- DOI
  10.1080/14017431.2022.2095013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08139, KAKENHI-PROJECT-21H04865, KAKENHI-PROJECT-18K08051
[Journal Article] Effects of Toxic AGEs (TAGE) on Human Health2022
- Author(s)
  Takeuchi Masayoshi、Sakasai-Sakai Akiko、Takata Takanobu、Takino Jun-ichi、Koriyama Yoshiki
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 14 Pages: 2178-2178
- DOI
  10.3390/cells11142178
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11583, KAKENHI-PROJECT-21K11607, KAKENHI-PROJECT-22K09844, KAKENHI-PROJECT-21H04865
[Journal Article] Front Pharmacol.2022
- Author(s)
  Ooi H, Nasu R, Furukawa A, Takeuchi M, Koriyama Y.
- Journal Title
  
  Front Pharmacol.
  
  Volume: 13 Pages: 921611-921611
- DOI
  10.3389/fphar.2022.921611
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09844, KAKENHI-PROJECT-21H04865
[Journal Article] Intracellular Toxic Advanced Glycation End-Products in 1.4E7 Cell Line Induce Death with Reduction of Microtubule-Associated Protein 1 Light Chain 3 and p622022
- Author(s)
  Takata Takanobu、Sakasai-Sakai Akiko、Takeuchi Masayoshi
- Journal Title
  
  Nutrients
  
  Volume: 14 Issue: 2 Pages: 332-332
- DOI
  10.3390/nu14020332
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04865, KAKENHI-PROJECT-21K11583, KAKENHI-PROJECT-21K11607
[Journal Article] The Association between Accumulation of Toxic Advanced Glycation End-Products and Cytotoxic Effect in MC3T3-E1 Cells2022
- Author(s)
  Sakasai-Sakai Akiko、Takata Takanobu、Takeuchi Masayoshi
- Journal Title
  
  Nutrients
  
  Volume: 14 Issue: 5 Pages: 990-990
- DOI
  10.3390/nu14050990
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04865, KAKENHI-PROJECT-21K11607
[Journal Article] Intracellular Toxic Advanced Glycation End-Products May Induce Cell Death and Suppress Cardiac Fibroblasts2022
- Author(s)
  Takata Takanobu、Sakasai-Sakai Akiko、Takeuchi Masayoshi
- Journal Title
  
  Metabolites
  
  Volume: 12 Issue: 7 Pages: 615-615
- DOI
  10.3390/metabo12070615
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11583, KAKENHI-PROJECT-21K11607, KAKENHI-PROJECT-21H04865
[Journal Article] 生活習慣病予防および健康寿命延伸における新規ターゲットToxic AGEs (TAGE)2021
- Author(s)
  竹内正義
- Journal Title
  
  金沢医科大学雑誌
  
  Volume: 46 Pages: 25-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04865
[Journal Article] Protective Effects of Collagen Tripeptides in Human Aortic Endothelial Cells by Restoring ROS-Induced Transcriptional Repression2021
- Author(s)
  Saito-Takatsuji Hidehito、Yoshitomi Yasuo、Ishigaki Yasuhito、Yamamoto Shoko、Numata Noriaki、Sakai Yasuo、Takeuchi Masayoshi、Tomosugi Naohisa、Katsuda Shogo、Yonekura Hideto、Ikeda Takayuki
- Journal Title
  
  Nutrients
  
  Volume: 13 Issue: 7 Pages: 2226-2226
- DOI
  10.3390/nu13072226
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04865, KAKENHI-PROJECT-19K07407, KAKENHI-PROJECT-21K09031
[Journal Article] Intracellular Toxic AGEs (TAGE) Triggers Numerous Types of Cell Damage.2021
- Author(s)
  Takeuchi M, Sakasai-Sakai A, Takata T, Takino JI, Koriyama Y, Kikuchi C, Furukawa A, Nagamine K, Hori T, Matsunaga T.
- Journal Title
  
  Biomolecules.
  
  Volume: 11 Issue: 3 Pages: 387-387
- DOI
  10.3390/biom11030387
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11781, KAKENHI-PROJECT-20K20320, KAKENHI-PROJECT-18K11003, KAKENHI-PROJECT-18K11139, KAKENHI-PROJECT-21H04865, KAKENHI-PROJECT-21K11583
[Journal Article] NAFLD/ALDとToxic AGEs (TAGE)2021
- Author(s)
  逆井(坂井)亜紀子、竹内正義
- Journal Title
  
  糖尿病・内分泌代謝科
  
  Volume: 52 Pages: 50-57
- NAID
  40022471867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04865
[Journal Article] グリセルアルデヒド由来終末糖化産物起因性のアルツハイマー病発症機序の解明2021
- Author(s)
  那須隆斗、古川絢子、竹内正義、郡山惠樹
- Journal Title
  
  アグリバイオ
  
  Volume: 5 Pages: 64-67
- NAID
  40022735522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04865
[Journal Article] Accumulation of Toxic Advanced Glycation End-Products Induces Cytotoxicity and Inflammation in Hepatocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells2021
- Author(s)
  Kikuchi Chigusa、Sakasai-Sakai Akiko、Okimura Risa、Tanaka Hinako、Takata Takanobu、Takeuchi Masayoshi、Matsunaga Tamihide
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 10 Pages: 1399-1402
- DOI
  10.1248/bpb.b21-00520
- NAID
  130008095843
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-10-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04865, KAKENHI-PROJECT-21K11583, KAKENHI-PROJECT-21K11607
[Journal Article] RasGRP2 inhibits glyceraldehyde-derived toxic advanced glycation end-products from inducing permeability in vascular endothelial cells2021
- Author(s)
  Takino Jun-ichi、Sato Takuma、Kanetaka Takumi、Okihara Kasumi、Nagamine Kentaro、Takeuchi Masayoshi、Hori Takamitsu
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 2959-2959
- DOI
  10.1038/s41598-021-82619-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11036, KAKENHI-PROJECT-21H04865
[Journal Article] Trapa bispinosa Roxb. extract lowers advanced glycation end-products and increases live births in older patients with assisted reproductive technology: a randomized controlled trial2021
- Author(s)
  Jinno Masao、Nagai Ryoji、Takeuchi Masayoshi、Watanabe Aiko、Teruya Koji、Sugawa Hikari、Hatakeyama Naohisa、Jinno Yuichi
- Journal Title
  
  Reproductive Biology and Endocrinology
  
  Volume: 19 Issue: 1 Pages: 149-149
- DOI
  10.1186/s12958-021-00832-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04865
[Journal Article] Serum levels of 1,5-anhydroglucitol and 1,5-anhydrofructose-derived advanced glycation end products in patients undergoing hemodialysis2021
- Author(s)
  Tanaka Kenji、Sakasai-Sakai Akiko、Motomiya Yasuki、Yoneda Tatsuo、Takeuchi Masayoshi
- Journal Title
  
  Diabetology & Metabolic Syndrome
  
  Volume: 13 Issue: 1 Pages: 85-85
- DOI
  10.1186/s13098-021-00685-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04865, KAKENHI-PROJECT-21K11583
[Journal Article] 第3のグリコーゲン代謝産物1,5-アンヒドロ-D-フルクトース(1,5-AF)の謎を探る2020
- Author(s)
  逆井(坂井)亜紀子、高田尊信、鈴木宏一、丸山征郎、田中賢治、本宮善恢、竹内正義
- Journal Title
  
  日本未病学会雑誌
  
  Volume: 26 Pages: 67-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H01811
[Journal Article] Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver2019
- Author(s)
  Takata Takanobu、Sakasai-Sakai Akiko、Takino Jun-ichi、Takeuchi Masayoshi
- Journal Title
  
  Nutrients
  
  Volume: 11 Issue: 7 Pages: 1612-1612
- DOI
  10.3390/nu11071612
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11003, KAKENHI-PROJECT-16H01811
[Journal Article] Immunological evidence for in vivo production of novel advanced glycation end-products from 1,5-anhydro-D-fructose, a glycogen metabolite2019
- Author(s)
  Sakasai-Sakai Akiko、Takata Takanobu、Suzuki Hirokazu、Maruyama Ikuro、Motomiya Yoshihiro、Takeuchi Masayoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 10194-10194
- DOI
  10.1038/s41598-019-46333-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11003, KAKENHI-PROJECT-18K11139, KAKENHI-PROJECT-16H01811, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587
[Journal Article] Intracellular toxic advanced glycation end-products in cardiomyocytes may cause cardiovascular disease2019
- Author(s)
  Takata Takanobu、Sakasai-Sakai Akiko、Ueda Tadashi、Takeuchi Masayoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 2121-2121
- DOI
  10.1038/s41598-019-39202-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11003, KAKENHI-PROJECT-18K11139, KAKENHI-PROJECT-16H01811
[Journal Article] The Relevance of Toxic AGEs (TAGE) Cytotoxicity to NASH Pathogenesis: A Mini-Review2019
- Author(s)
  Sakasai-Sakai Akiko、Takata Takanobu、Takino Jun-ichi、Takeuchi Masayoshi
- Journal Title
  
  Nutrients
  
  Volume: 11 Issue: 2 Pages: 462-462
- DOI
  10.3390/nu11020462
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11003, KAKENHI-PROJECT-16H01811
[Journal Article] 生活習慣病の発症・進展における新規バイオマーカーToxic AGEs (TAGE)2018
- Author(s)
  高田尊信、逆井(坂井)亜紀子、竹内正義
- Journal Title
  
  日本未病システム学会雑誌
  
  Volume: 24, No.2 Pages: 27-33
- NAID
  40021676781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H01811
[Journal Article] NAFLDとALDの発症・進展におけるToxic AGEs（TAGE）病因説2018
- Author(s)
  逆井(坂井)亜紀子、瀧野純一、福村敦、高田尊信、堤幹宏、竹内正義
- Journal Title
  
  日本未病システム学会雑誌
  
  Volume: 24, No.1 Pages: 19-25
- NAID
  40021547961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H01811
[Journal Article] Ratio of serum levels of AGEs to soluble RAGE is correlated with trimethylamine-N-oxide in non-diabetic subjects2017
- Author(s)
  Tahara A, Tahara N, Yamagishi SI, Honda A, Igata S, Nitta Y, Bekki M, Nakamura T, Sugiyama Y, Sun J, Takeuchi M, Shimizu M, Yamazaki H, Fukami K, Fukumoto Y
- Journal Title
  
  Int J Food Sci Nutr
  
  Volume: 68 Issue: 8 Pages: 1013-1020
- DOI
  10.1080/09637486.2017.1318117
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16030, KAKENHI-PROJECT-16H01811, KAKENHI-PROJECT-26461097, KAKENHI-PROJECT-17K09564
[Journal Article] Role of Glyceraldehyde-Derived AGEs and Mitochondria in Superoxide Production in Femoral Artery of OLETF Rat and Effects of Pravastatin2017
- Author(s)
  Hori E, Kikuchi C, Nagami C, Kajikuri J, Itoh T, Takeuchi M, and Matsunaga T
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 40 Issue: 11 Pages: 1903-1908
- DOI
  10.1248/bpb.b17-00411
- NAID
  130006191808
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Open Access
- Data Source
  KAKENHI-PROJECT-16H01811
[Journal Article] 非アルコール性脂肪性肝疾患 (NAFLD) の発症・進展におけるToxic AGEs (TAGE) の関与2017
- Author(s)
  竹内正義、逆井亜紀子、高田尊信、上田忠司、瀧野純一
- Journal Title
  
  日本未病システム学会雑誌
  
  Volume: 23 Pages: 20-30
- NAID
  40021180181
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H01811
[Journal Article] Diurnal glycemic fluctuation is associated with severity of coronary artery disease in prediabetic patients: Possible role of nitrotyrosine and glyceraldehyde-derived advanced glycation end products.2017
- Author(s)
  Watanabe M, Kawai Y, Kitayama M, Akao H, Motoyama A, Wakasa M, Saito R, Aoki H, Fujibayashi K, Tsuchiya T, Nakanishi H, Saito K, Takeuchi M, and Kajinami K
- Journal Title
  
  J. Cardiol.
  
  Volume: 69 Issue: 4 Pages: 625-631
- DOI
  10.1016/j.jjcc.2016.07.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H01811
[Journal Article] Effect of Collagen Tripeptide on Atherosclerosis in Healthy Humans2017
- Author(s)
  Tomosugi N, Yamamoto S, Takeuchi M, Yonekura H, Ishigaki Y, Numata N, Katsuda S, and Sakai Y
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 24 Issue: 5 Pages: 530-538
- DOI
  10.5551/jat.36293
- NAID
  130005631706
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H01811
[Journal Article] Toxic AGE (TAGE) theory for the pathophysiology of the onset/progression of NAFLD and ALD.2017
- Author(s)
  Takeuchi M, Takino J, Sakasai-Sakai A, Takata T, and Tsutsumi M
- Journal Title
  
  Nutrients
  
  Volume: 9 Issue: 6 Pages: 634-634
- DOI
  10.3390/nu9060634
- NAID
  40021547961
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H01811, KAKENHI-PROJECT-15K16239
[Journal Article] Impact of intracellular glyceraldehyde-derived advanced glycation end-products on human hepatocyte cell death.2017
- Author(s)
  Sakasai-Sakai A, Takata T, Takino J, and Takeuchi M
- Journal Title
  
  Sci. Rep.
  
  Volume: 7 Issue: 1 Pages: 14282-14282
- DOI
  10.1038/s41598-017-14711-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H01811, KAKENHI-PROJECT-15K16239
[Journal Article] Glyceraldehyde-derived advanced glycation end products accumulate faster than N-(carboxymethyl)lysine.2017
- Author(s)
  Yokota M, Sekita M, Okano Y, Masaki H, Takeuchi M, and Tokudome Y
- Journal Title
  
  Ann. Dermatol.
  
  Volume: 29 Issue: 4 Pages: 508-511
- DOI
  10.5021/ad.2017.29.4.508
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H01811
[Journal Article] Glyceraldehyde-derived advanced glycation end products are present in skin and accumulate faster than N-(carboxymethyl)lysine.2017
- Author(s)
  Yokota M, Sekita M, Okano Y, Masaki H, Takeuchi M, and Tokudome Y
- Journal Title
  
  Exp. Dermatol.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H01811
[Journal Article] ERAP1 protein identified as a potential non-invasive biomarker for nonalcoholic steatohepatitis related to glycated heterogeneous nuclear ribonucleoprotein M.2017
- Author(s)
  Takino J, Nagamine K, Nagai S, Yamane J, Hiraishi I, Sakasai-Sakai A, Takeuchi M, and Hori T.
- Journal Title
  
  Hepatol. Res.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H01811
[Journal Article] High doses of antipsychotic polypharmacy are related to an increase in serum levels of pentosidine in patients with schizophrenia.2017
- Author(s)
  Sannohe T, Ohnuma T, Takeuchi M, Tani E, Miki Y, Takeda M, Katsuta N, Takebayashi Y, Nakamura T, Nishimon S, Kimoto A, Higashiyama R, Shibata N, Gohda T, Suzuki Y, Yamagishi S, Tomino Y, and Arai H.
- Journal Title
  
  Prog. Neuropsychopharmacol. Biol. Psychiatry
  
  Volume: 76 Pages: 42-48
- DOI
  10.1016/j.pnpbp.2017.02.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H01811
[Journal Article] Effect of collagen tripeptide on atherosclerosis in healthy humans.2017
- Author(s)
  Tomosugi N, Yamamoto S, Takeuchi M, Yonekura H, Ishigaki Y, Numata N, Katsuda S, and Sakai Y.
- Journal Title
  
  J. Atheroscler. Thromb.
  
  Volume: 印刷中
- NAID
  130005631706
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H01811
[Journal Article] Gene expression changes associated with the loss of heterogeneous nuclear ribonucleoprotein M function2017
- Author(s)
  Jun-ichi Takino, Kentaro Nagamine, Mikoto Suzuki, Akiko Sakasai-Sakai, Masayoshi Takeuchi, Takamitsu Hori
- Journal Title
  
  American Journal of Molecular Biology
  
  Volume: 7 Issue: 02 Pages: 87-98
- DOI
  10.4236/ajmb.2017.72007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K00931, KAKENHI-PROJECT-16H01811, KAKENHI-PROJECT-15K16239
[Journal Article] Generation of glyceraldehyde-derived advanced glycation end-products in pancreatic cancer cells and the potential of tumor promotion.2017
- Author(s)
  Takata T, Ueda T, Sakasai-Sakai A, and Takeuchi M
- Journal Title
  
  World J. Gastroenterol.
  
  Volume: 23 Issue: 27 Pages: 4910-4919
- DOI
  10.3748/wjg.v23.i27.4910
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H01811, KAKENHI-PROJECT-15K16239
[Journal Article] Serum levels of toxic AGEs (TAGE) may be a promising novel biomarker for the onset/progression of lifestyle-related diseases.2016
- Author(s)
  Takeuchi M
- Journal Title
  
  Diagnostics
  
  Volume: 6 Issue: 2 Pages: 23-23
- DOI
  10.3390/diagnostics6020023
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H01811
[Journal Article] Acute effects of statin on reduction of angiopoietin-like 2 and glyceraldehyde-derived glycation end-products levels in patients with acute myocardial infarction: a message grom SAMIT (Statin for Acute Myocardial Infarction Trial).2016
- Author(s)
  Shimomura M, Oyama JI, Takeuchi M, Shibata Y, Yamamoto Y, Kawasaki T, Komoda H, Kodama K, Sakuma M, Toyoda S, Inoue Y, Mine D, Natsuaki M, Komatsu A, Hikichi Y, Yamagishi SI, Inoue T, Node K.
- Journal Title
  
  Heart Vessels
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Acute effects of statin on reduction of angiopoietin-like 2 and glyceraldehyde-derived glycation end-products levels in patients with acute myocardial infarction: a message grom SAMIT (Statin for Acute Myocardial Infarction Trial).2016
- Author(s)
  Shimomura M, Oyama JI, Takeuchi M, Shibata Y, Yamamoto Y, Kawasaki T, Komoda H, Kodama K, Sakuma M, Toyoda S, Inoue Y, Mine D, Natsuaki M, Komatsu A, Hikichi Y, Yamagishi SI, Inoue T, and Node K.
- Journal Title
  
  Heart Vessels.
  
  Volume: 31 Issue: 10 Pages: 1583-1589
- DOI
  10.1007/s00380-015-0773-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H01811
[Journal Article] NAFLDとALDの発症・進展におけるToxic AGEs (TAGE) の関与2016
- Author(s)
  竹内正義、瀧野純一、堤幹宏
- Journal Title
  
  アルコールと医学生物学
  
  Volume: 35 Pages: 20-22
- Data Source
  KAKENHI-PROJECT-16H01811
[Journal Article] 不妊治療バイオマーカーとしてのToxic AGEs (TAGE) の有用性2015
- Author(s)
  逆井（坂井）亜紀子、神野正雄、竹内正義
- Journal Title
  
  日本未病システム学会雑誌
  
  Volume: 21 Pages: 93-96
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Assessment of the contents of various advanced glycation end-products in commonly consumed beverages and foods in Japanese culture.2015
- Author(s)
  Takeuchi M, Takino J, Furuno S, Shirai H, Kawakami M, Muramatsu M, Kobayashi Y, Yamagishi S.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: e0118652-e0118652
- DOI
  10.1371/journal.pone.0118652
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Elevation of serum levels of advanced glycation end products in patients with non-B or non-C hepatocellular carcinoma.2015
- Author(s)
  Kan H, Yamagishi S, Ojima A, Fukami K, Ueda S, Takeuchi M, Hyogo H, Aikata H, Chayama K.
- Journal Title
  
  J. Clin. Lab. Anal.
  
  Volume: ２９ Issue: 6 Pages: 480-484
- DOI
  10.1002/jcla.21797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Assessment of the concentrations of total sugars and glucose in beverages that are Commonly Consumed in Japan.2015
- Author(s)
  Takeuchi M, Takino J, Shirai H, Kawakami M, Furuno S, Kobayashi Y.
- Journal Title
  
  Nutr. Food Technol
  
  Volume: １ Pages: 2-2
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Ratio of serum levels of AGEs to soluble form of RAGE is a predictor of endothelial function.2015
- Author(s)
  Kajikawa M, Nakashima A, Fujimura N, Maruhashi T, Iwamoto Y, Iwamoto A, Matsumoto T, Oda N, Hidaka T, Kihara Y, Chayama K, Goto C, Aibara Y, Noma K, Takeuchi M, Matsui T, Yamagishi S, Higashi Y.
- Journal Title
  
  Diabetes Care.
  
  Volume: 38(1) Issue: 1 Pages: 119-25
- DOI
  10.2337/dc14-1435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591055, KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-25670762
[Journal Article] Oral L-carnitine supplementation increases trimethylamine-N-oxide, but reduces markers of vascular injury in hemodialysis patients.2015
- Author(s)
  Fukami K, Yamagishi S, Sakai K, Kaida Y, Yokoro M, Ueda S, Wada Y, Takeuchi M, Shimizu M, Yamazaki H, Okuda S.
- Journal Title
  
  J. Cardiovasc. Pharmacol.
  
  Volume: 65. Issue: 3 Pages: 289-295
- DOI
  10.1097/fjc.0000000000000197
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-26860487, KAKENHI-PROJECT-25460198
[Journal Article] 脂質異常患者に対する脂質低下療法がGlycer-AGEsにもたらす影響2015
- Author(s)
  廣正修一、竹内正義
- Journal Title
  
  診療と新薬
  
  Volume: 52 Pages: 513-519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] 現代の食生活に潜む落とし穴～飲食物中AGEs及び糖毒性の真実～2015
- Author(s)
  竹内正義、瀧野純一、古野理美、白井ひかり、河上美穂子、村松充、小林由佳
- Journal Title
  
  日本未病システム学会雑誌
  
  Volume: 21 Pages: 53-58
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] 生活習慣病の発症・進展におけるToxic AGEs (TAGE) の関与：－新たな予防戦略－～食事性AGEsおよび糖毒性の真実～2015
- Author(s)
  竹内正義、瀧野純一、逆井（坂井）亜紀子、高田尊信、上田忠司
- Journal Title
  
  金医大誌
  
  Volume: ４０ Pages: 95-103
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] The association between glyceraldehyde-derived advanced glycation end-roducts and colorectal cancer risk.2015
- Author(s)
  Kong SY, Takeuchi M,他４６名（２/４８）
- Journal Title
  
  Cancer Epidemiol. Biomarkers Prev.
  
  Volume: ２４ Issue: 12 Pages: 1855-1863
- DOI
  10.1158/1055-9965.epi-15-0422
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Altered serum glyceraldehyde-derived advanced glycation end product (AGE) and soluble AGE receptor levels indicate carbonyl stress in patients with schizophrenia.2015
- Author(s)
  Takeda M, Ohnuma T, Takeuchi M, Katsuta N, Maeshima H, Takebayashi Y, Higa M, Nakamura T, Nishimon S, Sannohe T, Hotta Y, Hanzawa R, Higashiyama R, Shibata N, Gohda T, Suzuki Y, Yamagishi S, Tomino Y, Arai H.
- Journal Title
  
  Neurosci. Lett.
  
  Volume: ５９３ Pages: 51-55
- DOI
  10.1016/j.neulet.2015.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] In vivo identification of nonalcoholic fatty liver disease-related protein hnRNPM.2015
- Author(s)
  Takino J, Nagamine K, Takeuchi M, Hori T.
- Journal Title
  
  World J. Gastroenterol.
  
  Volume: 21 Issue: 6 Pages: 1784-1793
- DOI
  10.3748/wjg.v21.i6.1784
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Contribution of toxic advanced glycation end-products-receptor axis in nonalcoholic steatohepatitis-related hepatocellular carcinoma.2015
- Author(s)
  Takino J, Nagamine K, Hori T, Sakasai-Sakai A, Takeuchi M.
- Journal Title
  
  World J. Hepatol.
  
  Volume: ７ Issue: 23 Pages: 2459-2469
- DOI
  10.4254/wjh.v7.i23.2459
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-15K16239
[Journal Article] Toxic AGEs (TAGE) theory in the pathogenesis of NAFLD and ALD.2015
- Author(s)
  Takeuchi M, Sakasai-Sakai A, Takino J, Takata T, Ueda T, Tsutsumi M.
- Journal Title
  
  Int. J. Diabetes Clin. Res.
  
  Volume: ２ Pages: 4-4
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Serum levels of toxic AGEs (TAGE) may be a promising novel biomarker in development and progression of NASH.2015
- Author(s)
  Takeuchi M, Sakasai-Sakai A, Takata T, Ueda T, Takino J, Tsutsumi M, Hyogo H, Yamagishi S.
- Journal Title
  
  Med. Hypotheses
  
  Volume: ８４ Issue: 5 Pages: 490-493
- DOI
  10.1016/j.mehy.2015.02.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-15K16239
[Journal Article] Glyceraldehyde caused Alzheimer’s disease-like alterations in levels of diagnostic markers in SH-SY5Y cells.2015
- Author(s)
  Koriyama Y, Furukawa A, Muramatsu M, Takino J, Takeuchi M.
- Journal Title
  
  Sci. Rep.
  
  Volume: ５ Issue: 1 Pages: 13313-13313
- DOI
  10.1038/srep13313
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Clinical and biochemical factors associated with area and metabolic activity in the visceral and subcutaneous adipose tissues by FDG-PET/CT.2015
- Author(s)
  Tahara N, Yamagishi SI, Kodama N, Tahara A, Honda A, Nitta Y, Igata S, Matsui T, Takeuchi M, Kaida H, Kurata S, Abe T, Fukumoto Y
- Journal Title
  
  J. Clin. Endocrinol. Metab.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Clinical and Biochemical Factors Associated With Area and Metabolic Activity in the Visceral and Subcutaneous Adipose Tissues by FDG-PET/CT.2015
- Author(s)
  Tahara N, Yamagishi S, Kodama N, Tahara A, Honda A, Nitta Y, Igata S, Matsui T, Takeuchi M, Kaida H, Kurata S, Abe T, Fukumoto Y.
- Journal Title
  
  J Clin Endocrinol Metab.
  
  Volume: 100 Issue: 5 Pages: E739-E747
- DOI
  10.1210/jc.2014-3896
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461097, KAKENHI-PROJECT-25282029
[Journal Article] Advanced glycation end products impair glucose-induced insulin secretion from rat pancreatic β-cells.2014
- Author(s)
  Hachiya H, Miura Y, Inoue K, Park KH, Takeuchi M, Kubota K.
- Journal Title
  
  J Hepatobiliary Pancreat Sci.
  
  Volume: 21 Issue: 2 Pages: 624-630
- DOI
  10.1002/jhbp.12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] DNA aptamer raised against advanced glycation end products inhibits melanoma growth in nude mice2014
- Author(s)
  Ayako Ojima, Takanori Matsui, Sayaka Maeda, Masayoshi Takeuchi, Hiroyoshi Inoue, Yuichiro Higashimoto, Sho-ichi Yamagishi
- Journal Title
  
  Laboratory Investigation
  
  Volume: 94(4) Issue: 4 Pages: 422-429
- DOI
  10.1038/labinvest.2014.5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24550201, KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-25440056
[Journal Article] Involvement of the TAGE-RAGE system in NASH: Novel treatment strategies.2014
- Author(s)
  Takeuchi M, Takino J, Sakasai-Sakai A, Takata T, Ueda T, Tsutsumi M, Hyogo H, Yamagishi S.
- Journal Title
  
  World J. Hepatol
  
  Volume: 6 Issue: 12 Pages: 880-893
- DOI
  10.4254/wjh.v6.i12.880
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Amelioration of experimental autoimmune uveoretinitis by inhibition of glyceraldehyde derived-advanced glycation end product formation.2014
- Author(s)
  Dong Z, Iwata D, Kitaichi N, Takeuchi M, Sato M, Endo N, Iwabuchi K, Ando R, Fukuhara J, Kinoshita S, Lennikov A, Kitamura M, Mizuuchi K, Kanda A, Noda K, Namba K, Yamagishi S, Ohno S, Ishida S
- Journal Title
  
  J Leukoc Biol
  
  Volume: 96 Issue: 6 Pages: 1077-1085
- DOI
  10.1189/jlb.3a0513-288rrr
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390392, KAKENHI-PROJECT-24791823, KAKENHI-PROJECT-24791826, KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-25462731, KAKENHI-PROJECT-25462745, KAKENHI-PROJECT-25870708, KAKENHI-PROJECT-26462675, KAKENHI-PROJECT-26893004
[Journal Article] Possible effects of glimepiride beyond glycemic control in patients with type 2 diabetes: a preliminary report.2014
- Author(s)
  Nakamura I, Oyama J, Komoda H, Shiraki A, Sakamoto Y, Taguchi I, Hiwatashi A, Komatsu A, Takeuchi M, Yamagishi S, Inoue T, Node K.
- Journal Title
  
  Cardiovasc Diabetol.
  
  Volume: 13 Issue: 1 Pages: 15-15
- DOI
  10.1186/1475-2840-13-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Effect of statins on the serum soluble form of receptor for advanced glycation end-products and its association with coronary atherosclerosis in patients with angina pectoris.2014
- Author(s)
  Nozue T, Yamagishi S, Takeuchi M, Hirano T, Yamamoto S, Tohyama S, Fukui K, Umezawa S, Onishi Y, Kunishima T, Hibi K, Terashima M, Michishita I.
- Journal Title
  
  IJC Metabolic & Endocrine
  
  Volume: 4 Pages: 47-52
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Linagliptin blocks renal damage in type 1 diabetic rats by suppressing advanced glycation end products-receptor axis.2014
- Author(s)
  Nakashima S, Matsui T, Takeuchi M, Yamagishi S.
- Journal Title
  
  Horm. Metab. Res.
  
  Volume: 46 Issue: 10 Pages: 717-721
- DOI
  10.1055/s-0034-1371892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Switching to multiple daily injection therapy with glulisine improves glycemic control, vascular damage and treatment satisfaction in basal insulin glargine-injected diabetic patients.2014
- Author(s)
  Yanagisawa K, Ashihara J, Obata S, Wada N, Takeuchi M, Nishino Y, Maeda S, Ishibashi Y, Yamagishi S.
- Journal Title
  
  Diabetes Metab. Res. Rev.
  
  Volume: 30 Issue: 8 Pages: 693-700
- DOI
  10.1002/dmrr.2537
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Sulforaphane inhibits advanced glycation end product-induced pericyte damage by reducing expression of receptor for advanced glycation end products.2014
- Author(s)
  Maeda S, Matsui T, Ojima A, Takeuchi M, Yamagishi S.
- Journal Title
  
  Nutr. Res.
  
  Volume: 34 Issue: 9 Pages: 807-813
- DOI
  10.1016/j.nutres.2014.08.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] DNA aptamer raised against AGEs blocks the progression of experimental diabetic nephropathy.2013
- Author(s)
  Kaida Y,Fukami K, Matsui T,HigashimotoY,NishinoY,ObaraN,Nakayama Y, Ando R, Toyonaga M, Ueda S,TakeuchiM,InoueH,OkudaS,Yamagishi SI
- Journal Title
  
  Diabetes
  
  Volume: 62 Issue: 9 Pages: 3241-3250
- DOI
  10.2337/db12-1608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390111, KAKENHI-PROJECT-24550201, KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-25440056
[Journal Article] Serum levels of advanced glycation end products(AGEs) are independently correlated with circulating levels of dipeptidyl peptidase-4 (DPP-4) in humans.2013
- Author(s)
  TaharaN,Yamagishi,TakeuchiM(3/8)et・al.
- Journal Title
  
  Clin, Biochem
  
  Volume: 46 Issue: 4-5 Pages: 300-303
- DOI
  10.1016/j.clinbiochem.2012.11.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300264, KAKENHI-PROJECT-23591072
[Journal Article] Efficacy of alogliptin, a dipeptidyl peptidase-4 inhibitor, on glucose parameters, the activity of the advanced glycation end product (AGE) - receptor for AGE (RAGE) axis and albuminuria in Japanese type 2 diabetes.2013
- Author(s)
  Sakata K, Hayakawa M, Yano Y, Tamaki N, Yokota N, Eto T, Watanabe R, Hirayama N, Matsuo T, Kuroki K, Sagara S, Mishima O, Koga M, Nagata N, Nishino Y, Kitamura K, Kario K, Takeuchi M, Yamagishi S.
- Journal Title
  
  Diabetes Metab Res Rev.
  
  Volume: 29 Issue: 8 Pages: 624-630
- DOI
  10.1002/dmrr.2437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Relationship between advanced glycation end products and plaque progression in patients with acute coronary syndrome:The JAPAN-ACS Sub-study.2013
- Author(s)
  Fukushima Y, Daida H, Takeuchi M(7/13) et al.
- Journal Title
  
  Cardiovasc, Diabetol.
  
  Volume: 12 Issue: 1 Pages: 5-5
- DOI
  10.1186/1475-2840-12-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300264, KAKENHI-PROJECT-22390103, KAKENHI-PROJECT-23659256
[Journal Article] Blockade by phosphorothioate aptamers of advanced glycation end products-induced damage in cultured pericytes and endothelial cells2013
- Author(s)
  Higashimoto, Y., Matsui, T., Nishino, Y., Taira, J., Inoue, H., Takeuchi, M., Yamagishi, S.I.
- Journal Title
  
  Microvasc. Res.
  
  Volume: 90 Pages: 64-70
- DOI
  10.1016/j.mvr.2013.08.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24550201, KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-25440056, KAKENHI-PROJECT-25870990
[Journal Article] Presence of glyceraldehyde-derived advanced glycation end-products in the liver of insulin-resistant mice.2013
- Author(s)
  Ebata Y, Takino J, Tsuchiya H, Sakabe T, Ikeda Y, Hama S, Kogure K, Takeuchi M, Shiota G.
- Journal Title
  
  Int J Vitam Nutr Res.
  
  Volume: 83 Issue: 2 Pages: 137-141
- DOI
  10.1024/0300-9831/a000150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] 血管障害バイオマーカーとしてのtoxic AGEs (TAGE)2013
- Author(s)
  竹内　正義
- Journal Title
  
  医学のあゆみ
  
  Volume: 244 Pages: 685-690
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] Acetaldehyde-derived advanced glycation end-products promote alcoholic liver disease.2013
- Author(s)
  Hayashi N, George J, Takeuchi M, Fukumura A, Toshikuni N, Arisawa T, Tsutsumi M.
- Journal Title
  
  PLoS One.
  
  Volume: 8 Issue: 7 Pages: e70034-e70034
- DOI
  10.1371/journal.pone.0070034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Positive association between serum level of glyceraldehyde-derived advanced glycation end products (AGEs) and vascular inflammation evaluated by18F-fluorodeoxy- glucose positron emission tomography (FDG-PET).2012
- Author(s)
  Tahara N, Yamagishi S, Takeuchi M
- Journal Title
  
  Diabetes Care
  
  Volume: 35 Issue: 12 Pages: 2618-2625
- DOI
  10.2337/dc12-0087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300264, KAKENHI-PROJECT-23591072
[Journal Article] AGEsと肝疾患2012
- Author(s)
  竹内正義
- Journal Title
  
  Anti-aging Medicine
  
  Volume: 8 Pages: 55-61
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] 生活習慣病の発症・進展におけるToxic AGEs (TAGE)-RAGE系の関与：2012
- Author(s)
  竹内　正義
- Journal Title
  
  金沢医科大学雑誌
  
  Volume: 37 Pages: 141-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] AGEsと肝疾患2012
- Author(s)
  竹内　正義
- Journal Title
  
  Anti-aging Medicine
  
  Volume: 8 Pages: 53-61
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] Serum levels of advanced glycation end products (AGEs) are inversely associated with the number and migratory activity of circulating endothelial progenitor cells in apparently healthy subjects.2012
- Author(s)
  UedaS, Yamagishi S, Takeuchi M
- Journal Title
  
  Cardiovasc.Ther
  
  Volume: 30 Issue: 4 Pages: 249-254
- DOI
  10.1111/j.1755-5922.2011.00264.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] Glycer-AGEs-RAGE signaling enhances the angiogenic potential of HCC by upregulating VEGF expression.2012
- Author(s)
  Takino J, Yamagishi S, and Takeuchi M
- Journal Title
  
  World J.Gastroenterol.
  
  Volume: 18 Pages: 1781-1788
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] Serum levels of advanced glycation end products (AGEs) are independent correlates of insulin resistance in non-diabetic subjects.2012
- Author(s)
  TaharaN, YamagishiS, TakeuchiM
- Journal Title
  
  Cardiovasc.Ther.
  
  Volume: 30 Issue: 1 Pages: 42-48
- DOI
  10.1111/j.1755-5922.2010.00177.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300264, KAKENHI-PROJECT-23591072
[Journal Article] Toxic advanced glycation end-products: TAGEの多様な疾患への関与2012
- Author(s)
  竹内　正義
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 139 Pages: 193-197
- NAID
  10030572624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] Advanced glycation end-products accumulation compromises embryonic development and achievement of pregnancy by assisted reproductive technology.2011
- Author(s)
  Jinno M, Takeuchi M
- Journal Title
  
  Hum.Reprod.
  
  Volume: 26 Issue: 3 Pages: 604-610
- DOI
  10.1093/humrep/deq388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] 生活習慣病におけるToxic AGEs (TAGE)-RAGE系の関与とその阻止2011
- Author(s)
  竹内正義
- Journal Title
  
  日本未病システム学会雑誌
  
  Volume: 17 Pages: 73-79
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] NASHの発症・進展におけるtoxic AGEs (TAGE)-RAGE系の関与2011
- Author(s)
  竹内正義
- Journal Title
  
  アルコールと医学生物学
  
  Volume: 30 Pages: 100-106
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] 生活習慣病におけるTAGE病因説と食事性AGEsのクロストーク2010
- Author(s)
  竹内正義
- Journal Title
  
  Vitamembrane
  
  Volume: 10 Pages: 1-8
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] The formation of intracellular glyceraldehyde-derived advanced glycation end-products and cytotoxicity.2010
- Author(s)
  Takino J,Kobayashi Y and Takeuchi M
- Journal Title
  
  J. Gastroenterol
  
  Volume: 45 Pages: 646-655
- NAID
  10027216737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] Cancer malignancy is enhanced by glyceraldehyde-derived advanced glycation end-products.2010
- Author(s)
  Takino J, Yamagishi S, and Takeuchi M
- Journal Title
  
  Z.Oncol.2010
  
  Volume: 739852 Pages: 1-8
- DOI
  10.1155/2010/739852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] Involvement of the toxic AGEs (TAGE)- RAGE system in the pathogenesis of diabetic vascular complications:A novel therapeutic strategy.2010
- Author(s)
  Takeuchi M, Takino J, and Yamagishi S
- Journal Title
  
  Curr.DrugTargets
  
  Volume: 11 Pages: 1468-1482
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] Involvement of the toxic AGEs (TAGE)-RAGE system in the pathogenesis of diabetic vascular complications : A novel therapeutic strategy2010
- Author(s)
  Masayoshi Takeuchi
- Journal Title
  
  Curr.Drug.Targets
  
  Volume: 11 Pages: 1468-1482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] Immunological detection of fructose-derived advanced glycation end-products2010
- Author(s)
  Masayoshi Takeuchi
- Journal Title
  
  Lab.Invest.
  
  Volume: 90 Pages: 1117-1127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] Immunological detection of fructose-derived advanced glycation end-products.2010
- Author(s)
  Takeuchi M, Iwaki M, Takino J etal.
- Journal Title
  
  Lab.Invest.
  
  Volume: 90 Pages: 1117-1127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] Involvement of TAGE-RAGE system in the pathogenesis of diabetic retinopathy2010
- Author(s)
  Masayoshi Takeuchi
- Journal Title
  
  J.Ophthalmol.
  
  Volume: 2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300264
[Journal Article] Involvement of toxic AGEs (TAGE) in the pathogenesis of diabetic vascular complications and Alzheimer's disease.2009
- Author(s)
  Takeuchi M & Yamagishi S
- Journal Title
  
  J. Alzheimers Dis. 16
  
  Pages: 845-858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300254
[Journal Article] Effects of high-AGE beverage on RAGE and VEGF expression in the liver and kidneys.2009
- Author(s)
  Sato T, Takino J, Takeuchi M et al (3)
- Journal Title
  
  Eur. J. Nutr. 48
  
  Pages: 6-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300254
[Journal Article] Involvement of toxic AGEs (TAGE)in the pathogenesis of diabetic vascular complications and Alzheimer's disease.2009
- Author(s)
  Masavoshi Takeuchi
- Journal Title
  
  J. Alzheimers Dis. 16
  
  Pages: 1-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300254
[Journal Article] Possible involvement of advanced glycation end products (AGEs)in the pathogenesis of Alzheimer's disease.2008
- Author(s)
  Masayoshi Takeuchi
- Journal Title
  
  Curr. Pharm. Des. 14
  
  Pages: 973-978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300254
[Journal Article] Possible involvement of advanced glycation end products (AGEs) in the pathogenesis of Alzheimer's disease.2008
- Author(s)
  Takeuchi M & Yamagishi S
- Journal Title
  
  Curr. Pharm. Des. 14
  
  Pages: 973-978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300254
[Journal Article] Circulating advanced glycation end products (AGEs) and soluble form of receptor for AGEs (sRAGE) are independent determinants of serum monocyte chemoattractant protein-1 (MCP-1) levels in patients with type 2 diabets.2008
- Author(s)
  Nakamura K, Yamagishi S, Takeuchi M et al (5)
- Journal Title
  
  Diabtes Metab. Res. Rev. 24
  
  Pages: 109-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300254
[Journal Article] Glyceraldehyde-derived advanced glycation end products (AGEs): A novel biomarker of postprandial hyperglycemia in diabetic rats.2008
- Author(s)
  Kitahara Y, Takeuchi M et al (4)
- Journal Title
  
  Clin. Exp. Med. 8
  
  Pages: 175-177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300254
[Journal Article] Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells.2008
- Author(s)
  Iwamoto K, Kanno K, Takeuchi M et al (4)
- Journal Title
  
  J. Gastroenterol. 43
  
  Pages: 298-304
- NAID
  10021268317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300254
[Journal Article] 食事性AGEsと未病2008
- Author(s)
  竹内正義
- Journal Title
  
  未病と抗老化 17
  
  Pages: 32-39
- NAID
  40016029932
- Data Source
  KAKENHI-PROJECT-19300254
[Journal Article] Serum levels of soluble form of receptor for advanced glycation end products (sRAGE) are correlated with AGEs in both diabetic and non-diabetic subjects.2007
- Author(s)
  Nakamura k, Yamagishi S, Takeuchi M et al (3)
- Journal Title
  
  Clin. Exp. Med. 7
  
  Pages: 188-190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300254
[Journal Article] Short-chain aldehyde-derived ligands for RAGE and their actions on endothelial cells.2007
- Author(s)
  Yamamoto Y, Yonekura H, Takeuchi M (8)
- Journal Title
  
  Diabetes Res. Clin. Pract. 77 Suppl 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300254
[Journal Article] Diagnostic utility of serum or cerebrospinal fluid levels of toxic advanced glycation end-products (TAGE) in early detection of Alzheimer's disease.2007
- Author(s)
  Takeuchi M, Sato T, Takino J et al (4)
- Journal Title
  
  Med. Hypotheses 69
  
  Pages: 1358-1366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300254
[Journal Article] Serum level of advanced glycation end-products (AGEs) is an independent determinant of plasminogen activator inhibitor-1 (PAI-1) in nondiabetic general population.2007
- Author(s)
  Yamagishi S, Adachi H, Takeuchi M et al (5)
- Journal Title
  
  Horm. Metab. Res. 39
  
  Pages: 845-848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300254
[Patent] 終末糖化産物に対する抗体およびその使用2017
- Inventor(s)
  竹内正義、山本哲郎、土田仁美、森岡弘志、山内聡一郎
- Industrial Property Rights Holder
  竹内正義、山本哲郎、土田仁美、森岡弘志、山内聡一郎
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16H01811
[Patent] 終末糖化産物に対する抗体およびその使用2017
- Inventor(s)
  竹内正義，山本哲郎，土田仁美，森岡弘志，山内聡一郎
- Industrial Property Rights Holder
  竹内正義，山本哲郎，土田仁美，森岡弘志，山内聡一郎
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-168387
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17H04105
[Patent] カスパーゼ－３の異常高分子化を抑制または抑止する物質のスクリーニング法2015
- Inventor(s)
  逆井亜紀子、竹内正義
- Industrial Property Rights Holder
  学校法人金沢医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-189096
- Filing Date
  2015-09-28
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 生活習慣病予測マーカーとしてのTAGE2024
- Author(s)
  竹内正義
- Organizer
  日本薬学会第144年会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] グリセルアルデヒドによるグルタミン酸トランスポーターの発現変動解析2024
- Author(s)
  古川絢子、西森千紗、竹内正義、郡山恵樹
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] TAGE化β-チューブリンによる神経軸索伸長阻害に対するAGEs阻害剤の軽減作用2024
- Author(s)
  西城秀幸、大井勇秀、古川絢子、竹内正義、郡山恵樹
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] グリセルアルデヒド標的タンパク質の探索とその病理学的意義について2024
- Author(s)
  荻田翼、古川絢子、大井勇秀、加藤紘基、竹内正義、郡山恵樹
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] Toxic AGEs (TAGE) の概要2024
- Author(s)
  竹内正義
- Organizer
  日本薬学会第144年会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] TAGE化β-チューブリンによる神経軸索伸長の抑制とピリドキサミンによる軽減作用2024
- Author(s)
  大井勇秀、古川絢子、竹内正義、郡山恵樹
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] SH-SY5Y細胞におけるグリセルアルデヒド（GA）によるタウのリン酸化促進作用2024
- Author(s)
  トゥイーディー亜蘭、大井勇秀、古川絢子、竹内正義、郡山恵樹
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] TAGEと肝障害2024
- Author(s)
  坂井亜紀子、竹田健史、竹内正義
- Organizer
  日本薬学会第144年会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] 神経細胞におけるTAGE化標的タンパク質の探索とその生理的意義2023
- Author(s)
  大井勇秀、古川絢子、竹内正義、郡山恵樹
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] Toxic AGEs (TAGE)と健康2023
- Author(s)
  竹内正義
- Organizer
  第23回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] 糖代謝中間体グリセルアルデヒドが引き起こす骨芽細胞障害2023
- Author(s)
  坂井(逆井)亜紀子、竹田健史、竹内正義
- Organizer
  第23回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] Novel approach: Elucidating the intracellular clearance mechanism of toxic AGEs (TAGE) utilizing the artificial CHK1 mutant d270KD as a substrate model2023
- Author(s)
  Takeda Kenji、Sakai-Sakasai Akiko、Kajinami Kouji、Takeuchi Masayoshi
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] Toxic AGEs (TAGE) と健康2023
- Author(s)
  坂井亜紀子、竹田健史、竹内正義
- Organizer
  第27回糖化ストレス研究会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] グリセルアルデヒド（GA）による神経細胞障害：アルツハイマー病マーカーとの相関性2023
- Author(s)
  重野穫、大井勇秀、説田麻美子、古川絢子、竹内正義、郡山恵樹
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] β-チューブリンの毒性終末糖化産物化（TAGE化）による凝集作用2023
- Author(s)
  堀田夏未、大井勇秀、中島汰圭朗、古川絢子、竹内正義、郡山恵樹
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] ヒトの健康に対するToxic AGEs (TAGE)の影響2023
- Author(s)
  竹内正義、逆井(坂井)亜紀子、高田尊信、郡山恵樹、古川絢子、瀧野純一、長嶺憲太郎、堀隆光、菊池千草、堀英生、岩尾岳洋、松永民秀
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] ヒトiPS細胞由来脳毛細血管内皮細胞を用いたBBB-on-a-chipの開発,2023
- Author(s)
  竹内規晃、山下美紗季、坡下真大、岩尾岳洋、常喜祥子、広瀬賢一、山中誠、小柳博、畠山健治、松永民秀
- Organizer
  日本薬学会第143回年会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] 抗糖化食品ヒシエキスは、終末糖化産物低下により高齢者生殖補助医療の出産率を著しく増加する：前方視的無作為試験2023
- Author(s)
  神野正雄、竹内正義、渡辺愛子、畠山尚久
- Organizer
  第23回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] AGEs阻害剤はβ-チューブリンのTAGE化を介した神経軸索変性を軽減する2022
- Author(s)
  那須隆斗、古川絢子、竹内正義、郡山恵樹
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] 高血糖とアルコール大量摂取は肝臓でのアルドース還元酵素発現の誘導を介してGA-AGEsの蓄積を促進する2022
- Author(s)
  橋爪智恵子、福村敦、齋藤隆、利國信行、竹内正義、堤幹宏、土島睦
- Organizer
  第41回アルコール医学生物学会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] 高血糖とアルコール大量摂取は肝臓でのアルドース還元酵素発現の誘導を介してGA-AGEsの蓄積を促進する2022
- Author(s)
  橋爪智恵子、福村敦、齋藤隆、尾﨑一晶、竹内正義、堤幹宏、土島睦
- Organizer
  第58回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] グリセルアルデヒド(GA)およびGA由来AGEs(TAGE)による骨芽細胞障害2022
- Author(s)
  逆井(坂井)亜紀子、高田尊信、竹内正義
- Organizer
  第65回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] 生活習慣病予防および健康寿命延伸における新規ターゲットToxic AGEs (TAGE)2022
- Author(s)
  竹内正義、高田尊信、逆井(坂井)亜紀子、瀧野純一、郡山恵樹、松永民秀
- Organizer
  第22回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] 生活習慣病における新たな概念Toxic AGEs (TAGE)2022
- Author(s)
  竹内正義、逆井(坂井)亜紀子、高田尊信、瀧野純一、郡山恵樹、古川絢子、那須隆斗、菊池千草、長嶺憲太郎、堀隆光、松永民秀
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] 生活習慣病予防における新規ターゲットToxic AGEs (TAGE)2022
- Author(s)
  竹内正義、逆井(坂井)亜紀子、高田尊信
- Organizer
  第65回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] 毒性終末糖化産物（TAGE）の生成・蓄積が引き起こす心筋細胞および心臓線維芽細胞障害2022
- Author(s)
  高田尊信、逆井(坂井)亜紀子、竹内正義
- Organizer
  第70回日本心臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] SH-SY5Y細胞におけるTAGE標的タンパク質の探索とその生理学的意義2022
- Author(s)
  大井勇秀、古川絢子、竹内正義、郡山恵樹
- Organizer
  第68回日本薬学会東海支部大会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] NASHの発症・進展における新たな概念：Toxic AGEs（TAGE）2021
- Author(s)
  竹内正義、福村敦、土島睦、堤幹宏
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] 生活習慣病の発症・進展予防における新規概念Toxic AGEs (TAGE)と食事療法2021
- Author(s)
  高田尊信、逆井(坂井)亜紀子、瀧野純一、竹内正義
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] 毒性終末糖化産物 (TAGE) によるアルツハイマー病神経原線維変化の可能性について2021
- Author(s)
  那須隆斗、古川絢子、竹内正義、郡山恵樹
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2021
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] Accumulation of toxic advanced glycation end-products induces cell death and inhibits osteoblastic differentiation in MC3T3-E1 cells2021
- Author(s)
  逆井(坂井)亜紀子、髙田尊信、竹内正義
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] コラーゲン・トリペプチドは血管内皮細胞を酸化ストレスから保護する効果を持つ2021
- Author(s)
  高辻英仁、吉冨泰央、石垣靖人、山本祥子、沼田徳暁、酒井康夫、竹内正義、友杉直久、勝田省吾、米倉秀人、池田崇之
- Organizer
  第84回日本生化学大会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] 肝実質細胞内における毒性AGEs（TAGE）蓄積が酸化ストレスに及ぼす影響2021
- Author(s)
  逆井(坂井)亜紀子、高田尊信、瀧野純一、竹内正義
- Organizer
  第7回肝臓と糖尿病・代謝研究会学会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] アルコール性および非アルコール性脂肪肝に及ぼす終末糖化産物（AGEs）の影響2021
- Author(s)
  福村敦、竹内正義、齊藤隆、林伸彦、津村崇、楠野颯樹、山形光慶、野村匡晃、久保田龍一、平川祐希、松江泰弘、湊貴浩、尾﨑一晶、利國信行、堤幹宏、土島睦
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-21H04865
[Presentation] 食後高血糖マーカー1,5-AG前駆体1,5-Anhydro-D-fructose(1,5-AF)の謎を解明する2020
- Author(s)
  逆井(坂井)亜紀子、竹内正義、高田尊信、鈴木宏一、丸山征郎、本宮善恢
- Organizer
  第23回日本病態栄養学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 終末糖化産物による血管透過性亢進に対するRasGRP2の影響2020
- Author(s)
  堀隆光、長嶺憲太郎、竹内正義、瀧野純一
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] グリセルアルデヒド由来Toxic AGEs化βチュブリン由来の神経軸索伸長阻害作用2020
- Author(s)
  郡山恵樹、那須隆斗、古川絢子、竹内正義
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 心筋細胞内毒性終末糖化産物(toxic AGEs, TAGE)が心血管疾患を発症させる2020
- Author(s)
  髙田尊信、逆井(坂井)亜紀子、竹内正義
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] Glycogen代謝中間体1,5-Anhydro-D-fructose由来新規AGEsの免疫学的証拠2020
- Author(s)
  竹内正義、逆井(坂井)亜紀子、高田尊信、鈴木宏一、丸山征郎、本宮善恢
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] iPS細胞由来肝細胞におけるToxic AGEs(TAGE)の生成2020
- Author(s)
  田中日向子、沖村里咲、菊池千草、竹内正義、松永民秀
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] HFCS (High Fructose Corn Syrup) が尿路結石形成に及ぼす機序の解明2019
- Author(s)
  井上慎也、國井建司郎、牛本千春子、中澤佑介、中村有香、高田尊信、石垣靖人、竹内正義、宮澤克人
- Organizer
  第23回北陸泌尿器科Basic Research Meeting
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 肝星細胞の活性化における終末糖化産物（AGEs）の細胞死抑制2019
- Author(s)
  瀧野純一、長嶺憲太郎、佐藤拓真、竹内正義、堀隆光
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 血中Toxic AGEs (TAGE) は生活習慣病予防/健康寿命延伸の新規バイオマーカー2019
- Author(s)
  高田尊信、竹内正義、逆井(坂井)亜紀子、兵庫秀幸、神野正雄
- Organizer
  第19回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 結石研究における継承と創生-学内の輪：総合医学研究所との共同研究-2019
- Author(s)
  井上慎也、國井建司郎、牛本千春子、中澤佑介、中村有香、高田尊信、石垣靖人、竹内正義、宮澤克人
- Organizer
  第29回日本尿路結石症学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 終末糖化産物による血管障害に対する防御因子の研究2019
- Author(s)
  沖原香純、瀧野純一、佐藤拓真、長嶺憲太郎、竹内正義、堀隆光
- Organizer
  日本薬学会第58回中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] Toxic AGEs(TAGE)を防いで生活習慣病予防-NASH、食後高血糖、心血管疾患から不妊症まで-2019
- Author(s)
  竹内正義
- Organizer
  東北フレイル研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] Glycer-AGEs化チュブリンの重合による軸索伸長阻害作用2019
- Author(s)
  那須隆斗、古川絢子、竹内正義、郡山恵樹
- Organizer
  第28回海馬・高次脳機能学会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 生活習慣病における新規ターゲットToxic AGEs (TAGE)～NASH、糖尿病、心血管疾患から不妊症まで～2019
- Author(s)
  竹内正義
- Organizer
  第53回日本成人病（生活習慣病）学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] グリセルアルデヒド由来のAGEs化βチュブリンの異常重合と軸索伸長阻害について2019
- Author(s)
  郡山恵樹、古川絢子、那須隆斗、竹内正義
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] Toxic AGEs(TAGE)生成・蓄積が引き起こす心筋細胞障害2019
- Author(s)
  高田尊信、逆井-坂井亜紀子、竹内正義
- Organizer
  第34回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] HFCS(High-fructose corn syrup)が尿路結石形成に及ぼす機序の解明2019
- Author(s)
  井上慎也、國井建司郎、牛本千春子、中澤佑介、中村有香、高田尊信、石垣靖人、竹内正義、宮澤克人
- Organizer
  第29回日本尿路結石症学会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] TAGEの最新知見とコラーゲントリペプチド2019
- Author(s)
  竹内正義
- Organizer
  ゼライス研究セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 血中Toxic AGEs (TAGE) は生活習慣病予防および健康寿命延伸における新規バイオマーカー2019
- Author(s)
  竹内正義、逆井亜紀子、高田尊信
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] NASHの発症・進展における新規ターゲット分子Toxic AGEs(TAGE)2019
- Author(s)
  福村敦、竹内正義、兵庫秀幸、土島睦、堤幹宏
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 非アルコール性脂肪肝炎(NASH)の発症・進展におけるToxic AGEs(TAGE)の関与2019
- Author(s)
  竹内正義、瀧野純一、逆井(坂井)亜紀子、高田尊信
- Organizer
  第73回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 第3のグリコーゲン代謝産物1,5-アンヒドロ-D-フルクトース(1,5-AF)の謎を探る2019
- Author(s)
  竹内正義、逆井(坂井)亜紀子、高田尊信、鈴木宏一、丸山征郎、田中賢治、本宮善恢
- Organizer
  第26回日本未病システム学会学術総会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 非アルコール性脂肪肝炎(NASH)の発症・進展における新規ターゲット毒性終末糖化産物(toxic AGEs, TAGE)2019
- Author(s)
  逆井(坂井)亜紀子、竹内正義、高田尊信、瀧野純一
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 膵癌細胞内におけるグリセルアルデヒド由来終末糖化産物の生成・蓄積と膵癌促進の可能性2018
- Author(s)
  高田尊信、逆井(逆井)亜紀子、竹内正義
- Organizer
  第28回日本メイラード学会年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 肝星細胞の活性化における終末糖化産物（AGEs）の影響2018
- Author(s)
  瀧野純一、長嶺憲太郎、佐藤拓真、竹内正義、堀隆光
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] NASHの発症・進展における新規ターゲットToxic AGEs (TAGE)2018
- Author(s)
  竹内正義、瀧野純一、逆井(逆井)亜紀子、高田尊信
- Organizer
  第33回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 生活習慣病の発症・進展における新規バイオマーカー Toxic AGEs (TAGE)2018
- Author(s)
  竹内正義、逆井亜紀子、高田尊信
- Organizer
  第72回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] ヒト株化膵管上皮癌培養細胞におけるTAGE生成／蓄積と膵癌促進の可能性2018
- Author(s)
  高田尊信、逆井（坂井）亜紀子、竹内正義
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] Toxic AGEs (TAGE) と生活習慣病～NASH、食後高血糖、心血管疾患から不妊症まで～2018
- Author(s)
  竹内正義
- Organizer
  第59回日本人間ドック学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] Toxic AGEs (TAGE) は生活習慣病の新規バイオマーカーである2018
- Author(s)
  竹内正義、高田尊信、逆井(逆井)亜紀子
- Organizer
  第25回日本未病システム学会学術総会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] グリセルアルデヒドによるβチュブリンのGlycer-AGEs化と神経軸索伸長阻害作用2018
- Author(s)
  郡山恵樹、古川絢子、鈴木啓太、那須隆斗、竹内正義
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] RNA結合蛋白質HNRNPMのノックダウンによる下流遺伝子の網羅的解析2018
- Author(s)
  長嶺憲太郎、瀧野純一、和氣亜莉沙、安田華織子、竹内正義、堀隆光
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 生活習慣病の発症・進展における新規ターゲットToxic AGEs (TAGE)～メタボ、糖尿病から合併症まで～2018
- Author(s)
  竹内正義
- Organizer
  第18回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] NAFLD/ALDの発症・進展におけるToxic AGEs (TAGE) 病因説2018
- Author(s)
  竹内正義、逆井（坂井）亜紀子、高田尊信、瀧野純一、堤幹宏
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] グリセルアルデヒドによるβチューブリンのAGEs化と神経軸索伸長阻害作用2018
- Author(s)
  郡山恵樹、古川絢子、鈴木啓太、那須隆平、竹内正義
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 肝実質細胞死におけるグリセルアルデヒド由来終末糖化産物の関与2018
- Author(s)
  逆井(逆井)亜紀子、高田尊信、竹内正義
- Organizer
  第28回日本メイラード学会年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] アルコール（AL）性および非AL性脂肪性肝疾患におけるacetaldehydeおよびglyceraldehyde由来終末糖化産物（AGEs）の臨床的意義2018
- Author(s)
  福村敦、竹内正義、林伸彦、齊藤隆、久保田龍一、豊田健、平川祐希、中村彰伸、湊貴浩、松江泰弘、尾崎一晶、利國信行、土島睦、堤幹宏
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 非アルコール性及びアルコール性肝疾患の発症・進展に共通する新規ターゲット分子Toxic AGEs (TAGE)2018
- Author(s)
  高田尊信、逆井亜紀子、瀧野純一、堤幹宏、竹内正義
- Organizer
  第18回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] NAFLD/ALDの発症・進展におけるToxic AGEs (TAGE) の関与2018
- Author(s)
  逆井(逆井)亜紀子、高田尊信、瀧野純一、堤幹宏、竹内正義
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] コラーゲン・トリペプチドのヒト動脈硬化への影響2017
- Author(s)
  山本祥子、友杉直久、竹内正義、米倉秀人、石垣靖人、沼田徳暁、勝田省吾、酒井康夫
- Organizer
  第71回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] ヒト株化膵管上皮癌培養細胞におけるTAGE生成／蓄積と膵癌促進の可能性2017
- Author(s)
  高田尊信、逆井（坂井）亜紀子、竹内正義
- Organizer
  日本糖尿病学会第91回中部地方会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 糖尿病の発症・進展におけるTAGEの関与-新たな予防概念-2017
- Author(s)
  逆井（坂井）亜紀子、高田尊信、竹内正義
- Organizer
  日本糖尿病学会第91回中部地方会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 生活習慣病の発症・進展におけるToxic AGEs (TAGE) の関与-新たな予防概念-2017
- Author(s)
  高田尊信、逆井（坂井）亜紀子、瀧野純一、竹内正義
- Organizer
  第17回日本抗加齢医学会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 肝実質細胞死におけるグリセルアルデヒド由来終末糖化産物の関与2017
- Author(s)
  逆井（坂井）亜紀子、高田尊信、竹内正義
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] NAFLDとALDの発症・進展におけるToxic AGEs（TAGE）の関与2017
- Author(s)
  逆井（坂井）亜紀子、竹内正義、瀧野純一、高田尊信、堤幹宏
- Organizer
  第24回日本未病システム学会学術総会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 生活習慣病の発症・進展における新規バイオマーカーとしてのToxic AGEs (TAGE)2017
- Author(s)
  高田尊信、逆井（坂井）亜紀子、竹内正義
- Organizer
  第24回日本未病システム学会学術総会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 初代培養心筋、肝細胞における終末糖化産物の影響2017
- Author(s)
  上田忠司、高田尊信、竹内正義
- Organizer
  第122回日本解剖学会総会・全国学術集会
- Place of Presentation
  長崎大学坂本キャンパス（長崎県・長崎市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] HNRNPMノックダウンによる遺伝子発現変化の解析-リキッドバイオプシーによる非アルコール性脂肪肝炎の診断を目指して-2017
- Author(s)
  鈴木美琴、長嶺憲太郎、瀧野純一、佐藤拓真、竹内正義、堀隆光
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター他（宮城県・仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] ぶどう膜炎患者硝子体での終末糖化産物の検討2017
- Author(s)
  水内一臣、南場研一、北市伸義、竹内正義、鈴木智浩、齋藤理幸、岩田大樹、加瀬諭、石田晋
- Organizer
  フォーサム2017大阪
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] コラーゲン・トリペプチドの動脈硬化関連因子に対する影響2017
- Author(s)
  山本祥子、唐立華、友杉直久、竹内正義、沼田徳暁、勝田省吾、酒井康夫
- Organizer
  第49回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 糖尿病の発症・進展におけるToxic AGEs (TAGE) の関与-新たな予防概念-2017
- Author(s)
  逆井（坂井）亜紀子、高田尊信、瀧野純一、竹内正義
- Organizer
  第60回日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] 初代培養心筋、肝細胞における終末糖化産物の影響2017
- Author(s)
  上田忠司、高田尊信、竹内正義
- Organizer
  第１２２回日本解剖学会総会・全国学術集会
- Place of Presentation
  長崎大学坂本キャンパス（長崎県長崎市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K12742
[Presentation] 生活習慣病の発症・進展における新規バイオマーカーとしてのToxic AGEs (TAGE)2017
- Author(s)
  竹内正義、瀧野純一、逆井（坂井）亜紀子、高田尊信、上田忠司
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター他（宮城県・仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] NASHの発症・進展における毒性終末糖化産物（Toxic AGEs, TAGE）の関与2016
- Author(s)
  竹内正義、瀧野純一、堤　幹宏
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ幕張他（千葉県・千葉市）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] NASHの発症・進展予防におけるToxic AGEs（TAGE）の関与2016
- Author(s)
  竹内正義、逆井（坂井）亜紀子、瀧野純一
- Organizer
  第3回肝臓と糖尿病・代謝研究会
- Place of Presentation
  石川県立音楽堂（石川県・金沢市）
- Year and Date
  2016-07-16
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] Glycer-AGEsによる神経細胞障害とアルツハイマー病バイオマーカー変化2016
- Author(s)
  郡山恵樹、古川絢子、瀧野純一、竹内正義
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 非アルコール性脂肪性肝障害（NAFLD）の発症・進展におけるToxic AGEs（TAGE）の関与2016
- Author(s)
  竹内正義、逆井亜紀子、高田尊信、上田忠司、瀧野純一
- Organizer
  第23回日本未病システム学会総会学術総会
- Place of Presentation
  九州大学医学部百年講堂（福岡県・福岡市）
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] Glycer-AGE化タンパク質からのアルツハイマー病バイオマーカー探索変化2016
- Author(s)
  鈴木啓太、古川絢子、竹内正義、郡山恵樹
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] Glycer-AGEsに関連したNASHの非侵襲的バイオマーカー探索2016
- Author(s)
  瀧野純一、長嶺憲太郎、永井真也、山根　惇、平石　勇、逆井（坂井）亜紀子、竹内正義、堀　隆光
- Organizer
  第55回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  岡山国際会議場（岡山県・岡山市）
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] グリセルアルデヒド誘導糖化皮膚モデルにおける化合物皮膚透過性の評価2016
- Author(s)
  関田真理絵、横田真美、竹内正義、徳留嘉寛
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] PANC-1における細胞内TAGE生成とTAGE化蛋白質の探索2016
- Author(s)
  高田尊信、逆井（坂井）亜紀子、上田忠司、竹内正義
- Organizer
  第31回日本糖尿病合併症学会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16H01811
[Presentation] ヒト膵管癌培養細胞における細胞内TAGE蓄積と細胞障害関連蛋白質の探索2016
- Author(s)
  高田尊信、逆井（坂井）亜紀子、上田忠司、竹内正義
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] Toxic AGEs はヒト真皮線維芽細胞のECM合成のバランスを崩す2016
- Author(s)
  西川功征、水谷多恵子、岡野由利、竹内正義、正木仁
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] NAFLDとALDの発症・進展におけるToxic AGEs (TAGE) の関与2016
- Author(s)
  竹内正義、瀧野純一、堤幹宏
- Organizer
  第35回アルコール医学生物学研究会学術集会
- Place of Presentation
  リーガロイヤルホテル東京（東京都新宿区）
- Year and Date
  2016-01-22
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 糖化hnRNPMによる遺伝子発現変化の解析2016
- Author(s)
  長峰憲太郎、瀧野純一、永井真也、山根惇、平石勇、竹内正義、堀隆光
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] NAFLDとALDの発症・進展におけるToxic AGEs (TAGE) の関与2016
- Author(s)
  瀧野純一、長嶺憲太郎、堀隆光、堤幹宏、竹内正義
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 培養心筋細胞における細胞内TAGE生成／蓄積と心筋細胞障2016
- Author(s)
  上田忠司、高田尊信、竹内正義
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] The presence of glyceraldehyde-derived AGEs in the skin2015
- Author(s)
  Mami Yokota, Yuri Okano, Hitoshi Masaki, Masayoshi Takeuchi, Yoshihiro Tokudome
- Organizer
  日本研究皮膚科学会第40回年次学術大会・総会
- Place of Presentation
  岡山コンベンションセンター（岡山県岡山市）
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] オンライン血液透析濾過の血清グリセルアルデヒド由来AGEs（TAGE）への効果2015
- Author(s)
  中澤了一、清水洋一、大川智、齋藤佑司、柏原英彦、小野隆、松金隆夫、渋谷泰史、東仲宣、竹内正義
- Organizer
  第60回日本透析医学会学術集会・総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 飲食物中AGEs及び糖毒性の真実2015
- Author(s)
  瀧野純一、永井真也、山根惇、古野理美、白井ひかり、河上美穂子、村松充、小林由佳、竹内正義
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学他（兵庫県神戸市）
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 非アルコール性脂肪性肝疾患 (NAFLD) の診断マーカーの探索2015
- Author(s)
  長嶺憲太郎、瀧野純一、竹内正義、堀隆光
- Organizer
  Biochemistry and Molecular Biology (BMB) 2015，第38回日本分子生物学会年会／第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 糖化のターゲット蛋白質であるhnRNPMの解析2015
- Author(s)
  山根惇、永井真也、瀧野純一、長峰憲太郎、竹内正義、堀隆光
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学他（兵庫県神戸市）
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 飲食物中AGEs及び糖毒性の真実～現代の食生活に潜む落とし穴～2015
- Author(s)
  竹内正義、古野理美、白井ひかり、河上美穂子、村松充、小林由佳、山岸昌一、瀧野純一
- Organizer
  第22回日本未病システム学会総会学術総会
- Place of Presentation
  北海道大学学術交流会館（北海道札幌市）
- Year and Date
  2015-10-11
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 飲食物中AGEs及び糖毒性の真実～現代の食生活に潜む落とし穴～2015
- Author(s)
  竹内正義、古野理美、白井ひかり、河上美穂子、村松充、小林由佳、山岸昌一、瀧野純一
- Organizer
  第15回日本抗加齢医学会総会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 抗糖化機能性食品ヒシエキスによるART妊娠率の著しい改善：ART反復不成功の高齢不妊に対する終末糖化産物低下の重要性2015
- Author(s)
  神野正雄、渡邊愛子、畠山尚久、合田友哉、日浦理絵、竹下祥子、上村知広、山田道生、竹内正義
- Organizer
  第33回日本受精着床学会総会・学術講演会
- Place of Presentation
  TFTホール（東京都江東区）
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] The effect of predilution on-line haemodiafiltration on serum glyceraldehyde-derived advanced glycation end-products (Toxic AGEs: TAGE) in haemodialysis patients.2015
- Author(s)
  Ryoichi Nakazawa, Yoichi Shimizu, Satoshi Ohkawa, Yuji Saito, Hidehiko Kashiwabara, Mutsumi Ono, Takao Matsugane, Yasushi Shibuya, Nakanobu Azuma, Masayoshi Takeuchi
- Organizer
  European Renal Association (ERA)-Europian Dialysis and transplant Association (EDTA) 2015
- Place of Presentation
  ExCeL London (London, United Kingdom)
- Year and Date
  2015-05-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 糖化を防いでアンチエイジング～現代の食習慣に潜むわな～2015
- Author(s)
  竹内正義
- Organizer
  Beautiful Life－第12章－～いきいきと輝いたセカンドライフを～　　奈良新聞社主催市民講演会　基調講演
- Place of Presentation
  奈良県橿原文化会館（奈良県橿原市）
- Year and Date
  2015-09-19
- Invited
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] アルコール性肝障害とNAFLDの病態に関与する終末糖化産物： AA-AGEsとGA-AGEsに関する検討2015
- Author(s)
  福村敦、竹内正義、堤幹宏
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 不妊治療バイオマーカーとしてのToxic AGEs (TAGE) の有用性2015
- Author(s)
  竹内正義、逆井（坂井）亜紀子、神野正雄
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学他（兵庫県神戸市）
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 真皮線維芽細胞の機能に及ぼすToxic AGEsの作用2015
- Author(s)
  西川攻征、水谷多恵子、岡野由利、竹内正義、正木仁
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学他（兵庫県神戸市）
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 飲食物中AGEs及び糖毒性の真実～新たな食事指導の概念～2015
- Author(s)
  竹内正義、瀧野純一、古野理美、白井ひかり、河上美穂子、村松充、小林由佳、山岸昌一
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関グランドホテル（山口県下関市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 不妊治療バイオマーカーとしてのToxic AGEs (TAGE) の有用性2014
- Author(s)
  竹内正義、逆井（坂井）亜紀子、神野正雄
- Organizer
  第21回日本未病システム学会学術総会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府大阪市）
- Year and Date
  2014-11-01
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 2型糖尿病モデルラット大腿動脈におけるAGEsによるスーパーオキシド産生増加およびプラバスタチンによる抑制効果機序の解明2014
- Author(s)
  堀英生、永味千枝、菊池千草、竹内正義、松永民秀
- Organizer
  第24回日本医療薬学会年会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 不妊治療バイオマーカーとしてのToxic AGEs (TAGE)2014
- Author(s)
  逆井（坂井）亜紀子、神野正雄、竹内正義
- Organizer
  第14回日本抗加齢医学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2014-06-06
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] DNA-aptamer raised against RAGE blocks the progression of experimental diabetic neuropathy.2014
- Author(s)
  Kensei Taguchi, Kei Fukami, Sho-ichi Yamagishi, Yuichiro Higashimoto, Miyuki Yokoro, Nana Obara, Ryotaro Ando, Yosuke Nakayama, Takanori Matsui, Masayoshi Takeuchi, Seiji Ueda, Seiya Okuda.
- Organizer
  The 14th Asian Pacific Congress of Nephrology (APCN 2014) 2014
- Place of Presentation
  Shinagawa Prince Hotel（東京都港区）
- Year and Date
  2014-05-15
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] DPP-4阻害剤アナグリプチンの酸化ストレス抑制を介した血管障害抑制機序の解明2014
- Author(s)
  堀英生、永味千枝、菊池千草、竹内正義、松永民秀
- Organizer
  第88回日本糖尿病学会中部地方会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2014-10-26
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 高フルクトース曝露による細胞内Glycer-AGEsの形成2014
- Author(s)
  瀧野純一、長峰憲太郎、竹内正義、堀隆光
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本市総合体育館
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 糖化を防いで生活習慣病予防～Toxic AGEs (TAGE) 病因説からみた新たな予防/治療戦略～2014
- Author(s)
  竹内正義
- Organizer
  第63回日本医学検査学会
- Place of Presentation
  朱鷺メッセ新潟コンベンションセンター（新潟県新潟市）
- Year and Date
  2014-05-18
- Invited
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 糖化を防いで生活習慣病予防～Toxic AGEs (TAGE) 病因説からみた新たな予防/治療戦略～2014
- Author(s)
  竹内正義
- Organizer
  Grand Design by Japan, 2014
- Place of Presentation
  慶應義塾大学日吉キャンパス（神奈川県横浜市）
- Year and Date
  2014-04-13
- Invited
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 終末糖化産物特異的DNAアプタマーは、ヌードマウスにおけるメラノーマ増殖を抑制する2014
- Author(s)
  松井孝憲、尾崎亜弥子、前田沙耶香、竹内正義、東元佑一郎、山岸昌一
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 非B非C型肝癌におけるAGE測定の意義2014
- Author(s)
  菅宏美、兵庫秀幸、藤野初江、福原崇之、本田洋二、苗代典昭、宮本大輔、河岡友和、拓植雅貴、平松憲、今村道雄、川上由育、相方浩、茶山一彰、山岸昌一、竹内正義
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ（東京都千代田区）
- Year and Date
  2014-05-30
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 糖化を防いで生活習慣病予防～Toxic AGEs (TAGE) 病因説からみた新たな予防/治療戦略～2014
- Author(s)
  竹内正義
- Organizer
  NPO法人北陸ライフケアクラスター研究会
- Place of Presentation
  金沢都ホテル（石川県金沢市）
- Year and Date
  2014-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] Acetaldehyde-derived advanced glycation end-products promote alcoholic liver disease2013
- Author(s)
  Joseph George, Masayoshi Takeuchi, Mikihiko Tsutumi
- Organizer
  Digestive Disease Week 2013
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 新しい重症卵巣機能障害の治療法：sitagliptin による食後糖代謝是正は卵胞・胚発育，妊娠率を改善する2013
- Author(s)
  神野正雄，渡邉愛子，竹内正義，日浦理絵，廣濱準，畠山尚久
- Organizer
  第57回日本生殖医学会学術講演会・総会
- Place of Presentation
  長崎市長崎ブリックホール
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 肥満２型糖尿病モデルWBN/Kob-fattyラットの糖尿病性腎症の経過と腎臓におけるToxic AGEsの局在について2013
- Author(s)
  秋元敏雄，丸山基世，益田幸成，岡田嘉仁，竹内正義，鈴木龍一郎，福生吉裕
- Organizer
  第20回日本未病システム学会学術総会
- Place of Presentation
  東京都千代田区学術総合センター
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 糖化を防いで生活習慣病予防～ToxicAGEs(TAGE)-RAGE系からみた新たな戦略～2013
- Author(s)
  竹内正義
- Organizer
  日本薬学会東海支部特別講演
- Place of Presentation
  名古屋
- Year and Date
  2013-01-11
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 非アルコール性脂肪肝炎（NASH）の発症・進展におけるtoxic AGEs (TAGE) の関与2013
- Author(s)
  竹内正義，瀧野純一，兵庫秀幸，山岸昌一
- Organizer
  第20回日本未病システム学会学術総会
- Place of Presentation
  東京都千代田区学術総合センター
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 生活習慣病の発症・進展におけるToxicAGEs(TAGE)-RAGE系の関与とその阻止2013
- Author(s)
  竹内正義
- Organizer
  日本薬学会第133年会ランチョンセミナー特別講演
- Place of Presentation
  横浜
- Year and Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 糖尿病腎症治療薬としてのAGEs-DNA aptamer2013
- Author(s)
  深水圭，山岸昌一，甲斐田裕介，東元祐一郎，竹内正義，井上浩義，松井孝憲，奥田誠也
- Organizer
  第28回日本糖尿病合併症学会
- Place of Presentation
  旭川市旭川グランドホテル
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] Lanthanum suppresses AGEs-induced osteoblastic differentiation via inhibition of RAGE-ROS-NF-κB pathway in rat vascular smooth muscle cells.2013
- Author(s)
  Yosuke Nakayama, Kei Fukami, Sho-ichi Yamagishi, Yusuke Kaida, Ryotaro Ando, Nana Obara, Masayoshi Takeuchi, Seiji Ueda and Seiya Okuda.
- Organizer
  ERA-EDTA 50th Congress
- Place of Presentation
  Istanbul, Turkey
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 未病マーカーとしてのtoxic AGEs (TAGE) の有用性2013
- Author(s)
  竹内正義，兵庫秀幸，山岸昌一，神野正雄
- Organizer
  第20回日本未病システム学会学術総会
- Place of Presentation
  東京都千代田区学術総合センター
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 生活習慣病予防マーカーとしてのtoxic AGEs (TAGE)の有用性2012
- Author(s)
  竹内正義
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 未病におけるToxicAGEs(TAGE)の関与とその阻止2012
- Author(s)
  竹内正義
- Organizer
  第19回日本未病システム学会学術総会シンポジウム
- Place of Presentation
  金沢
- Year and Date
  2012-10-28
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 生活習慣病の発症・進展予防と糖化制御2012
- Author(s)
  竹内正義
- Organizer
  第7回日本栄養改善学会北陸支部学術総会特別講演
- Place of Presentation
  金沢
- Year and Date
  2012-02-26
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 糖化を防いで生活習慣病予防!～TAGE-RAGE系からみた新たな治療戦略～2012
- Author(s)
  竹内正義
- Organizer
  第5回抗加齢ウイメンズヘルス研究会特別講演
- Place of Presentation
  東京
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 生活習慣病の発症・進展予防と糖化制御2012
- Author(s)
  竹内正義
- Organizer
  第7回日本栄養改善学会北陸支部学術総会
- Place of Presentation
  石川県女性センター(石川県)(招待講演)
- Year and Date
  2012-02-26
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] NASHの発症・進展におけるtoxicAGEs(TAGE)-RAGE系の関与2012
- Author(s)
  竹内正義
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢
- Year and Date
  2012-06-08
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 生活習慣病におけるToxic AGEs (TAGE)-RAGE病因説と食事性AGEsのクロストーク2011
- Author(s)
  竹内正義
- Organizer
  第65回日本栄養・食糧学会
- Place of Presentation
  お茶の水女子大学(東京都)(招待講演)
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 心腎連関におけるTAGE-RAGE系の関与2011
- Author(s)
  竹内正義
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 生活習慣病の発症・進展におけるTAGE-RAGE系の関与2011
- Author(s)
  竹内正義
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡(中止により誌上発表)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 食後高血糖-酸化ストレス-心血管病連関とTAGE-RAGE系のクロストーク2011
- Author(s)
  竹内正義
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  さっぽろ芸術文化の館(北海道)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 生活習慣病におけるToxicAGEs(TAGE)-RAGE病因説と食事性AGEsのクロストーク2011
- Author(s)
  竹内正義
- Organizer
  第65回日本栄養・食糧学会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 非アルコール性脂肪性肝炎(NASH)の発症・進展におけるtoxic AGEs (TAGE)-RAGE系の関与2011
- Author(s)
  竹内正義
- Organizer
  第11回日本抗加齢医学会総会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 食後高血糖一酸化ストレスー心血管病連関とTAGE-RAGE系のクロストーク2011
- Author(s)
  竹内正義
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 生活習慣病の発症・進展におけるTAGE-RAGE系の関与2011
- Author(s)
  竹内正義
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 生活習慣病におけるTAGE-RAGE系の関与とその阻止2011
- Author(s)
  竹内正義
- Organizer
  第1回糖化ストレス研究会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 未病マーカーとしてのtoxic AGEs (TAGE)の役割2011
- Author(s)
  竹内正義
- Organizer
  第18回日本未病システム学会学術総会
- Place of Presentation
  今池ガスビル(愛知県)
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 生活習慣病におけるTAGE-RAGE系の関与とその阻止2011
- Author(s)
  竹内正義
- Organizer
  第1回糖化ストレス研究会
- Place of Presentation
  TKP東京駅八重洲カンファレンスセンター(東京都)(招待講演)
- Year and Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] アンチエイジングにおけるTAGE-RAGE系の関与2011
- Author(s)
  竹内正義
- Organizer
  第14回日本補完代替医療学会シンポジウム
- Place of Presentation
  金沢
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] アンチエイジングにおけるTAGE-RAGE系の関与2011
- Author(s)
  竹内正義
- Organizer
  第14回日本補完代替医療学会
- Place of Presentation
  石川県文教会館(石川県)(招待講演)
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 糖尿病血管合併症に関わる食後高血糖及び食事性AGEsとToxic AGEs (TAGE)-RAGE系のクロストーク2010
- Author(s)
  竹内正義
- Organizer
  第25回日本糖尿病合併症学会
- Place of Presentation
  大津
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 生活習慣病におけるToxic AGEs (TAGE)-RAGE系と食後高血糖及び食事性AGEsのクロストーク2010
- Author(s)
  竹内正義
- Organizer
  第17回日本未病システム学会学術総会
- Place of Presentation
  那覇
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] Toxic AGEs (TAGE)-RAGE病因説から考える未病と栄養2010
- Author(s)
  竹内正義
- Organizer
  第17回日本未病システム学会学術総会ワークショップ
- Place of Presentation
  那覇
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 生活習慣病の発症・進展におけるTAGE病因説と食事性AGEsのクロストーク2010
- Author(s)
  竹内正義
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 糖尿病血管合併症に関わる食後高血糖及び食事性AGEsとToxicAGEs(TAGE)-RAGE系のクロストーク2010
- Author(s)
  竹内正義
- Organizer
  第25回日本糖尿病合併症学会ワークショップ
- Place of Presentation
  大津
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 生活習慣病の発症・進展におけるtoxic AGEs (TAGE)病因説と食事性AGEsのクロストーク2010
- Author(s)
  竹内正義
- Organizer
  第64回日本栄養・食糧学会
- Place of Presentation
  徳島
- Year and Date
  2010-05-23
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 生活習慣病の発症・進展におけるtoxic AGEs (TAGE)病因説と食事性AGEsのクロストーク2010
- Author(s)
  竹内正義
- Organizer
  第55回日本透析医学会学術集会・総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] NASHの発症・進展におけるtoxic AGEs (TAGE)-RAGE系の関与2010
- Author(s)
  竹内正義
- Organizer
  第30回アルコール医学生物学研究会学術集会
- Place of Presentation
  久留米
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] Toxic AGEs (TAGE)-RAGE病因説とCVD-CKD連関2010
- Author(s)
  竹内正義
- Organizer
  第10回石川腎不全合併症研究会
- Place of Presentation
  金沢
- Year and Date
  2010-07-24
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] Toxic AGEs (TAGE)-RAGE病因説とアンチエイジング2010
- Author(s)
  竹内正義
- Organizer
  第10回日本抗加齢医学会総会
- Place of Presentation
  京都
- Year and Date
  2010-06-11
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] ToxicAGEs(TAGE)-RAGE病因説から考える未病と栄養2010
- Author(s)
  竹内正義
- Organizer
  第17回日本未病システム学会学術総会ワークショップ
- Place of Presentation
  那覇
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 生体内毒性AGEs(TAGE)形成と食事性AGEs のクロストークから食事指導を考える2009
- Author(s)
  竹内正義
- Organizer
  第54 回日本透析医学会
- Place of Presentation
  横浜
- Year and Date
  2009-06-06
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 内因性及び外因性AGEsからみた生活習慣病発症・進展予防の新たな考え方2009
- Author(s)
  竹内正義
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] Toxic AGEs(TAGE)の細胞障害性は食後高血糖と食事性AGEs によってコントロールされる2009
- Author(s)
  竹内正義
- Organizer
  第52 回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 内因性及び外因性AGEs からみた生活習慣病発症・進展予防の新たな考え方2009
- Author(s)
  竹内正義
- Organizer
  日本薬学会第129 年会
- Place of Presentation
  京都
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 生活習慣病の発症・進展における飲食品中AGEs の関与とクレメジンによるAGEs 除去効果2008
- Author(s)
  竹内正義
- Organizer
  第23 回日本糖尿病合併症学会
- Place of Presentation
  東京
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 生活習慣病における外因性AGEs の関与と吸着除去剤の有用性2008
- Author(s)
  竹内正義
- Organizer
  第20 回日本糖尿病性腎症研究会
- Place of Presentation
  東京
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 飲食品中に含まれるAGEsは生活習慣病の発症・進展に関連している2008
- Author(s)
  竹内正義
- Organizer
  第62回日本栄養・食糧学会大会
- Place of Presentation
  埼玉
- Year and Date
  2008-05-04
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 高AGEs含有飲食品は腎不全患者の病態に影響を及ぼすか?2008
- Author(s)
  竹内正義
- Organizer
  第51回日本腎臓学会
- Place of Presentation
  福岡
- Year and Date
  2008-05-31
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] TAGE (toxic AGEs)病因説における飲食品中AGEsの関与とクレメジンによるAGEs除去効果の検討2008
- Author(s)
  竹内正義
- Organizer
  第27回腎と骨代謝研究会
- Place of Presentation
  東京
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 飲食料品中に含まれているAGEsは生活習慣病の発症・進展に関連している2008
- Author(s)
  竹内正義
- Organizer
  第51回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 飲食料品中AGEsは生活習慣病の発症・進展にどの程度関連しているか?2008
- Author(s)
  竹内正義
- Organizer
  日本薬学会第128年会、横浜(2008.3)
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 飲食料品中AGEs は生活習慣病の発症・進展にどの程度関連しているか?2008
- Author(s)
  竹内正義
- Organizer
  日本薬学会第128 年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 高AGEs 含有飲食品は腎不全患者の病態に影響を及ぼすか?2008
- Author(s)
  竹内正義
- Organizer
  第51 回日本腎臓学会
- Place of Presentation
  福岡
- Year and Date
  2008-05-31
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 生活習慣病における終末糖化産物(AGEs)の関与とその阻止2008
- Author(s)
  竹内正義
- Organizer
  第34回関東Lipid Artery研究会
- Place of Presentation
  東京
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 高AGEs含有飲食品は透析患者の病態に影響を及ぼすか?2008
- Author(s)
  竹内正義
- Organizer
  第53回日本透析医学会
- Place of Presentation
  神戸
- Year and Date
  2008-06-22
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 高AGEs 含有飲食品は透析患者の病態に影響を及ぼすか?2008
- Author(s)
  竹内正義
- Organizer
  第53 回日本透析医学会
- Place of Presentation
  神戸
- Year and Date
  2008-06-22
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 飲食料品中に含まれているAGEs は生活習慣病の発症・進展に関連している2008
- Author(s)
  竹内正義
- Organizer
  第51 回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 生活習慣病における外因性AGEsの関与と吸着除去剤の有用性2008
- Author(s)
  竹内正義
- Organizer
  第20回日本糖尿病性腎症研究会
- Place of Presentation
  東京
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 生活習慣病の発症・進展における飲食晶中AGEsの関与とクレメジンによるAGEs除去効果2008
- Author(s)
  竹内正義
- Organizer
  第23回日本糖尿病合併症学会
- Place of Presentation
  東京
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 生活習慣病における終末糖化産物(AGEs)の関与とその阻止2007
- Author(s)
  竹内正義
- Organizer
  生体機能と創薬シンポジウム2007 金沢
- Place of Presentation
  金沢
- Year and Date
  2007-09-13
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 生活習慣病予防におけるTAGE(toxic AGEs)病因説と飲食品由来AGEsの寄与2007
- Author(s)
  竹内主義
- Organizer
  第61回日本栄養・食糧学会大会
- Place of Presentation
  京都
- Year and Date
  2007-05-19
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 食品由来advanced glycation end-products (AGEs):生活習慣病における新たな治療戦略2007
- Author(s)
  竹内正義
- Organizer
  第17 回日本メイラード学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2007-11-30
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 生活習慣病における終末糖化産物(AGEs)の関与とその阻止2007
- Author(s)
  竹内正義
- Organizer
  生体機能と創薬シンポジウム2007金沢
- Place of Presentation
  金沢
- Year and Date
  2007-09-13
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 食品由来advanced glycation end-products(AGEs):生活習慣病における新たな治療戦略2007
- Author(s)
  竹内正義
- Organizer
  第17回日本メイラード学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2007-11-30
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 生活習慣病におけるTAGE(toxic AGEs)病因説と外因性AGEsの寄与2007
- Author(s)
  竹内正義
- Organizer
  第50回日本糖尿病学会
- Place of Presentation
  仙台
- Year and Date
  2007-05-24
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] TAGE(toxic AGEs)病因説における外因性AGEsの寄与とクレメジン投与による外因性AGEsの除去効果2007
- Author(s)
  竹内正義
- Organizer
  第52回日本透析医学会
- Place of Presentation
  大阪
- Year and Date
  2007-06-16
- Data Source
  KAKENHI-PROJECT-19300254
[Presentation] 糖化を防いで生活習慣病予防〜Toxic AGEs (TAGE)-RAGE系からみた新たな戦略〜
- Author(s)
  竹内　正義
- Organizer
  日本薬学会東海支部特別講演会
- Place of Presentation
  名古屋市立大学薬学部
- Invited
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 非アルコール性脂肪肝炎（NASH）の発症・進展におけるtoxic AGEs（TAGE）の関与
- Author(s)
  竹内　正義
- Organizer
  第16回日本病態栄養学会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 生活習慣病の発症・進展予防と糖化制御
- Author(s)
  竹内　正義
- Organizer
  富山県栄養士会平成24年度生涯学習研修会
- Place of Presentation
  富山県総合福祉会館
- Invited
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 生活習慣病予防マーカーとしてのToxic AGEs (TAGE) 測定の意義
- Author(s)
  竹内　正義
- Organizer
  第12回日本抗加齢医学会総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 未病におけるToxic AGEs (TAGE) の関与とその阻止
- Author(s)
  竹内　正義
- Organizer
  第19回日本未病システム学会学術総会シンポジウム
- Place of Presentation
  金沢勤労者プラザ
- Invited
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] NASHの発症・進展におけるtoxic AGEs (TAGE) の関与
- Author(s)
  竹内　正義
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 糖尿病性腎症進展阻止をめざした次世代分子標的治療薬AGEs-aptamer の開発
- Author(s)
  甲斐田裕介，深水圭，松井孝憲，竹内正義，上田誠二，井上浩義，東元祐一郎，山岸昌一，奥田誠也
- Organizer
  第17回日本心血管内分泌代謝学会
- Place of Presentation
  大阪市千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 生活習慣病の発症・進展におけるToxic AGEs (TAGE)-RAGE系の関与と
- Author(s)
  竹内　正義
- Organizer
  日本薬学会第133年会ランチョンセミナー
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] NASHの発症・進展におけるtoxic AGEs (TAGE)-RAGE系の関与
- Author(s)
  竹内　正義
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-22300264
[Presentation] 糖化を防いで生活習慣病予防！〜TAGE-RAGE系からみた新たな治療戦略〜
- Author(s)
  竹内　正義
- Organizer
  第5回抗加齢ウィメンズヘルス研究会
- Place of Presentation
  東京ステーションコンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-22300264

1. TAKINO Jun-ichi (00440529)

# of Collaborated Projects: 5 results

# of Collaborated Products: 65 results
2. TAKATA Takanobu (20515308)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. UEDA Tadashi (80151794)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. 松永民秀 (40209581)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. 郡山恵樹 (70397199)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
6. SATO Takashi (30325451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. MAKITA Zenji (50261285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SASAKI Nobuyuki (60315497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KIKUCHI Seiji (10271660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. WATANABE Takuo (40303268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YAMAMOTO Yasuhiko (20313637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YONEKURA Hideto (80240373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MORIOKA Hiroshi (20230097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 小橋川敬博 (90455600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 佐藤卓史 (70555755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 石垣靖人 (20232275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. MATSUI Takanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. FURUKAWA Ayako

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. TAKEDA Kenji

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. KAIDA Hayato

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. HONDA AKIHIRO

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 杉山陽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 梶波康二

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. 逆井亜紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
25. 山岸昌一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 東元祐一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
27. 石田晋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 木原康樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 長嶺憲太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 堀隆光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 田原宣広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKEUCHI Masayoshi 竹内 正義

竹内 正義 タケウチ マサヨシ

Research Projects

Research Products

Co-Researchers

生活習慣病の新規概念「毒性終末糖化産物（Toxic AGEs）原因説」の確立Principal Investigator

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Review Section

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Developments of functional single-chain antibodies and unraveling of mechanisms of diseases associated with advanced glycation end-products

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Generation and accumulation of intracellular toxic advanced glycation end-products due to modern dietary habits and elucidation of relevant cytotoxic mechanismsPrincipal Investigator

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Excessive ingestion of sugar causes the abnomality of endoplasmic reticulum, resulting in providing for NASH

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Association between characteristics of current diet and onset/deterioration of non-alcoholic fatty liver diseasePrincipal Investigator

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1nvolvement of hyperglycemiaand dietary AGEs inthe prevention of life style-related diseasePrincipal Investigator

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Involvement of dietary AGEs in the life style-related diseasePrincipal Investigator

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Study on the mechanism of vascular injury by novel species of advanced glycation endoproducts

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The study for neurotoxicity of advanced glycation end-products (the structural epitope AGE-2) in neurodegenerative processesPrincipal Investigator

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Neurotoxicity of advanced glycation end products in Alzheimer disease

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[Book] 循環器病・介護予防に向けた未病ガイドライン-その根拠となる論文集-2016

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[Book] アンチエイジングのための100の質問2014

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[Book] アンチエイジングのための100の質問2014

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TAKEUCHI Masayoshi 竹内正義

竹内正義タケウチマサヨシ