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Kato Mitsuyasu  加藤 光保

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KATO Mitsuyasu  加藤 光保

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Researcher Number 20194855
Other IDs
External Links
Affiliation (Current) 2025: 筑波大学, 医学医療系, 教授
Affiliation (based on the past Project Information) *help 2011 – 2023: 筑波大学, 医学医療系, 教授
2007 – 2010: University of Tsukuba, 大学院・人間総合科学研究科, 教授
2006: University of Tsukuba, Graduate School of Comprehensive Human Sciences, Professor, 大学院人間総合科学研究科, 教授
2004 – 2005: 筑波大学, 大学院・人間総合科学研究科, 教授
2002 – 2003: 筑波大学, 基礎医学系, 教授 … More
2001: The Cancer Institute of the Japanese Foudnation for Cancer Research, Associate member, 癌研究所・生化学部, 主任研究員
2000 – 2001: (財)癌研究会, 癌研究所生化学部, 主任研究員
2000: (財)癌研究会, 癌研究所・生化学部, 研究員
2000: JAPANESE FOUNDATION FOR CANCER RESEARCH CANCER INSTITUTE, DEPARTMENT OF BIOCHEMISTRY ASSOCIATE MEMBER, 癌研究所・生化学部, 主任研究員
1998 – 1999: Japanese Foundation for Cancer Research, The Cancer Institute, Department of Biochemistry Fellow, 癌研究所・生化学部, 研究員
1998: 癌研究会, 癌研究所 生化学部, 研究員
1998: 癌研究会, 癌研究所生化学部, 研究員
1997 – 1998: 財団法人癌研究会, 癌研究所・生化学部, 研究員
1996 – 1997: The Cancer Inst., Jpn.Found.Cancer Res., Biochem, The Cancer Institute, Japanese Foundation for Cancer Research, Res.Fellow, 癌研究所生化学部, 研究員
1995 – 1997: 財団法人癌研究會, 癌研究所・生化学部, 研究員
1996: 財団法人癌研究會, 癌研究所生化学部, 研究員
1995: The Cancer Institute, Jpn Foundation for Cancer Res., Biochem., Research Fellow, 癌研究所生化学部, 研究員
1995: 財団法人癌研究曾, 癌研究所・生化学部, 研究員
1993 – 1994: 東北大学, 医学部, 助手
1987 – 1990: Tohoku University School of Medichine, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Experimental pathology / Experimental pathology / Biological Sciences / Medium-sized Section 50:Oncology and related fields / Basic Section 50010:Tumor biology-related / Tumor biology and related fields / Tumor biology / General medical chemistry
Except Principal Investigator
Cell biology … More / Experimental pathology / Biological Sciences / Experimental pathology / Human pathology / General medical chemistry / Gastroenterology / Pathological medical chemistry / Environmental pharmacy / General medical chemistry Less
Keywords
Principal Investigator
TGF-β / がん / Smad / 角化細胞 / 浸潤 / がん幹細胞 / 幹細胞 / TMEPAI / c-myc / SMAD … More / 扁平上皮癌 / 増殖抑制 / GPNMB / THG-1 / 転写 / c-Ski / transforming growth factor-β / LEF-1 / TCF-4 / WNT / Fas / E-selectin / IRF-1 / 細胞増殖動態 / 扁平上皮がん / MAFK / 特殊環状ペプチド / 足場非依存性増殖 / Gpnmb / MafK / 3次元培養 / 重層扁平上皮 / トランスフォーミング増殖因子β / Apc / 遺伝子改変マウス / β-catenin / 重層扁平上皮癌 / Smad蛋白 / マクロファージ / 3次元培養 / 細胞増殖 / 幹細胞性誘導 / 多色イメージングシステム / 多色イメージング / 生物発光共鳴エネルギー移行 / オルガノイド培養 / スフェア培養 / イメージング / 不均等分裂 / TMEPAI(PMEPA1) / 幹細胞誘導 / 抗体 / 休眠期がん細胞 / リン酸化 / 腫瘍形成能 / 乳がん / 乳癌 / 休眠がん細胞 / Glycoprotein NMB / 環状ペプチド / βカテニン / NRBP1 / KEAP1 / THG-1/TSC22D4 / SALL4 / HIF1α / NRF2 / TSC22D4/THG-1 / transcription / TBE3エレメント / β-catemin / smad / E2Fエレメント / TIE / invasion / Growth inhibition / Cancer / Bone morphogenetic protein / 癌 / トランスフォーミング増殖因子 / 骨形成因子 / invasive growth / autocrine / growth inhibition / transforming growth factor-beta / cancer / keratinocyte / trnsforming growth factor-β / 自己分泌 / linkage analysis / autoantibody / Eta-1 / cytokine / vasculitis / 骨髄キメラ / アロタイプ変異 / サイトカイン / アポトーシス / 背景遺伝子 / 糸球体腎炎 / 血管内皮細胞 / インターフェロン / マイクロサテライトマーカー / 疾患感受性遺伝子 / 動脈炎 / Sall4 / 間欠性増殖 / スフェア / Nrf2 / Keap-1 / がん細胞代謝 / RAS/MAPK経路 / 肺がん / 子宮頸がん / 食道がん / 上皮間葉転換 / 間欠的増殖 / マウスモデル / 炎症 / 大腸がん / 腸内細菌 / 3次元定量病理学 / 組織幹細胞 / 異型陰窩 / 大腸癌 / Bach1 / THG1(TSC22D4) / 腫瘍形成 / TCF4 / TGF-B / TGF7L2 / 抗酸化分子 / c-Tun / JunB / +>マウス / Apc^<min / ephrin-A1 / AP1 / 多層化 / 組織形成 / 病理組織学 / 標的遺伝子 / PMEPA1 / ELAC2 / Jun / 重層化 / ephrin / トランスジェニックマウス / Id-1 / Herp-2 / Smad2 / LEF / TCF / 精製 / 増殖抑制因子 / 分化 / 単球 / 血液細胞 … More
Except Principal Investigator
Smad / TGF-β / TGF-beta / シグナル伝達 / レセプター / BMP / アクチビン / 増殖抑制 / セリン-スレオニンキナーゼ / 血管新生 / signal transduction / 癌抑制遺伝子 / cDNAクローニング / 骨形成因子 / threonine kinase / serine / receptor / セリン・スレオニンキナーゼ / アポトーシス / MRL / Herp2 / Id1 / CGI-128 / E2-2 / 転写因子 / 受容体 / DPC4 / angiogenesis / growth inhibition / tumor suppressor gene / セリン-スレオニン・キナーゼ / Schnurri / 免疫抑制剤 / 細胞分化 / 環状ペプチド / Gpnmb / 分子標的治療 / 転移形成 / EMT / 腫瘍形成 / GPNMB / MafK / HLA-DR antigen / Synovial cell / Rheumatoid arthritis / 螢光抗体法 / DR抗原 / HLA / HLAーDR陽性細胞 / リウマトイド結節 / 清膜細胞 / HLAーDR抗原 / 滑膜細胞 / 慢性関節リウマチ / 1pr / Mp-1pr / rheumatoid arthritis / synovitis / polyarteritis / genetic analysis / granuloma / IL-1 / Class【II】抗原 / 遺伝的背景 / 多発性動脈炎 / l慢性関節リウマチ / マクロファージ / リンパ球 / 滑膜炎 / 関節炎 / 動脈炎 / 肉芽腫 / Embryonic lethality / Angiogenesis / 胎盤 / 胎生死 / transcription factor / ubiquitination / anti-oncogene / oncogene / がんの浸潤・転移 / シグナルクロストーク / Wntシグナル / Smurf1 / c-myc / ユビチキン化 / ユビキチン化 / 癌遺伝子 / cell differentiation / transcription / endotelial cell / invasion / DNA microarray / 表皮角化細胞 / 骨芽細胞 / 転写調節 / 血管内皮細胞 / 浸潤 / DNAマイクロアレイ / Drosophila / colorectal cancer / ショウジョウバエ / 大腸癌 / gene targeting / 遺伝子ターゲッテイング / keratinocyte / bone morphogenetic protein / activin / 皮膚角化細胞 / apoptosis / Cancer / Histogenesis / Keratinocytes / Autocrine / Growth Inhibitor / 単クローン抗体 / 精製 / 腫瘍 / 組織形成 / 角化細胞 / 自己分泌 / 増殖抑制因子 / 医薬様植物 / アルツハイマー病 / 肝炎 / 癌 / ホーチミン市 / HO-1 / 転写因子Nrf2 / 生理活性成分 / 南方薬 / 医薬用植物 / Heme oxygenase-1 / Nrf2 / Garcinia vilersiana / ベトナム / DNAチップ / BMPII型レセプター / リン酸化 / ファルネシレーション / FKBP-12 / 形態形成 Less
  • Research Projects

    (42 results)
  • Research Products

    (99 results)
  • Co-Researchers

    (30 People)
  •  Live imaging and counting system of stemness induction and cellular kinetics during persistent growth of cancer cellsPrincipal Investigator

    • Principal Investigator
      Kato Mitsuyasu
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      University of Tsukuba
  •  Induction of Cancer Stem Cell Properties by GPNMBPrincipal Investigator

    • Principal Investigator
      KATO Mitsuyasu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      University of Tsukuba
  •  Master Regulator of squamous cell carcinoma TSC22D4/THG-1 and its application for medical developmentPrincipal Investigator

    • Principal Investigator
      Kato Mitsuyasu
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Tumor biology and related fields
    • Research Institution
      University of Tsukuba
  •  Roles of MafK-Gpnmb axis in malignant progression of cancer and molecular targeted therapy

    • Principal Investigator
      OKITA Yukari
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Tsukuba
  •  足場非依存性間欠性細胞分裂の転写制御と代謝Principal Investigator

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  Roles of TGF-beta target genes TMEPAI and MafK on cancer developmentPrincipal Investigator

    • Principal Investigator
      Kato Mitsuyasu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Tsukuba
  •  Tumorigenic activity of tissue-specific oncogene THG-1Principal Investigator

    • Principal Investigator
      KATO Mitsuyasu
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor biology
    • Research Institution
      University of Tsukuba
  •  腸内細菌による大腸炎が大腸異型陰窩の幹細胞に作用し腺腫形成を誘導する機構Principal Investigator

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  Translational TGF-β Research for Diagnosis, Treatment, and Prevention of CancerPrincipal Investigator

    • Principal Investigator
      KATO Mitsuyasu
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Tsukuba
  •  がんの発生と進展におけるTGF-βシグナルの標的遺伝子TMEPAIの作用Principal Investigator

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  Exploration of bioactive compounds from traditional medicinal plants in Vietnam

    • Principal Investigator
      KANAHO Yasunori
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      University of Tsukuba
  •  がんの発生におけるTGFーβシグナルの役割に関する遺伝子改変マウスを用いた研究Principal Investigator

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  角化細胞による重層構造の形成を制御する分子機構の解明Principal Investigator

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      University of Tsukuba
  •  がんの進展に関わるTGF・βの標的遺伝子に関する遺伝子改変マウスを用いた研究Principal Investigator

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  角化細胞が3次元の組織構造を形成する分子機序の研究Principal Investigator

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      University of Tsukuba
  •  Regulation of endothelial cell activation by TGF-β family signaling

    • Principal Investigator
      ITOH Susumu
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      University of Tsukuba
  •  発がんにおけるTGF-βの役割に関する遺伝子改変マウスを用いた研究Principal Investigator

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  TGF-βシグナルの異常によるがんの悪性化に関する研究Principal Investigator

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  がんの悪性化に関与するTGF-βの標的遺伝子の研究Principal Investigator

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  Transcriptional regulation of the target genes of transforming growth factor-β and it's abnormalities in disease.Principal Investigator

    • Principal Investigator
      KATO Mitsuyasu
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Tsukuba
  •  BMPおよびアクチビンの細胞内シグナル伝達機構の解析

    • Principal Investigator
      川畑 正博
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Smadによる細胞増殖調節機構の解明

    • Principal Investigator
      川畑 正博
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Mechanisms of TGF-β signaling and its abnormalities in human cancer

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Signal transduction by Smad proteins and their biological activities

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      The University of Tokyo
      Japanese Foundation For Cancer Research
  •  Growth inhibition of keratinocytes by TGF-β and the impaired signaling in cancer cellsPrincipal Investigator

    • Principal Investigator
      KATO Mitsuyasu
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  がん細胞がTGF-βの増殖抑制活性に対する応答性を失う責任異常分子の同定Principal Investigator

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Japanese Foundation For Cancer Research
  •  がん細胞がTGF-βの増殖抑制活性に対する応答性を失う責任異常分子の同定Principal Investigator

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Signainrg Mechanism and Biological Action of the Members of the Transforming Growh Factor beta Superfamily

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Autocrine growth inhibitors of keratinocytes and their significance in carcinogenesisPrincipal Investigator

    • Principal Investigator
      KATO Mitsuyasu
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  The role of DPC4 and Smad family genes iu the carcinogenesis of the digestive system.

    • Principal Investigator
      KAWABATA Masahiro
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  TGF-βスーパーファミリーによる造血調節に関する基礎研究Principal Investigator

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  角化細胞増殖抑制因子の同定Principal Investigator

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Bioactivity and Clinical Application of New Members in the TGF-beta Superfamily

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  形態形成におけるアクチビンおよび骨形成因子レセプターの役割

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  血球細胞でのTGF-βとアクチビンレセプターの発現と造血調節機構の研究

    • Principal Investigator
      宮園 浩平
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  癌細胞の自律性増殖におけるTGF-βのシグナル伝達機構の役割

    • Principal Investigator
      宮園 浩平
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  TGF-βレセプターによるシグナル伝達機構の研究

    • Principal Investigator
      宮園 浩平
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Responsible proteins and genes for the development of intractable vasculitisPrincipal Investigator

    • Principal Investigator
      KATO Mitsuyasu
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      The Cancer Institute, Japanese Foundatiion for Cancer Research
  •  Mechanism of Action and Clinical Application of the Type beta Transforming Growth Factor

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Study of the autocrine growth inhibitors of the keratinocytes

    • Principal Investigator
      NOSE Masato
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Tohoku University
  •  HLA-DR Antigen Positive Cells in the RA Synovium. -Their Significant Role Concerning in the Continuation of Chronic Inflammation of RA.

    • Principal Investigator
      MURAKAMI Kazuhiro
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      TOHOKU UNIVERSITY
  •  Experimental Pathology of Granuloma Formation

    • Principal Investigator
      KYOGOKU Masahisa
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      TOHOKU UNIVERSITY

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All Journal Article Presentation Book Patent

  • [Book] TGF-βファミリーシグナルとその調節機構2007

    • Author(s)
      伊東 進, 加藤 光保
    • Publisher
      ューサイエンス社(In press)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390073
  • [Book] ルービン病理学2007

    • Author(s)
      加藤光保
    • Total Pages
      1367
    • Publisher
      西村書店
    • Data Source
      KAKENHI-PROJECT-19406003
  • [Journal Article] Glycoprotein nonmetastatic melanoma protein B impacts the malignant potential of bladder cancer cells through its hem‐immunoreceptor tyrosine‐based activation motif2024

    • Author(s)
      Kimura Tomokazu、Okita Yukari、Nagumo Yoshiyuki、Chin Jas Min、Fikry Muhammad Ali、Shiga Masanobu、Kandori Shuya、Kawahara Takashi、Suzuki Hiroyuki、Nishiyama Hiroyuki、Kato Mitsuyasu
    • Journal Title

      Pathology International

      Volume: - Issue: 5 Pages: 262-273

    • DOI

      10.1111/pin.13419

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07184, KAKENHI-PROJECT-20K20597
  • [Journal Article] he liver kinase B1 supports mammary epithelial morphogenesis by inhibiting critical factors that mediate epithelial-mesenchymal transition.2023

    • Author(s)
      Tzavlaki K, Ohata Y, Moren A, Watanabe Y, Eriksson J, Tsuchiya M, Kubo Y, Yamamoto K, Sellin ME, Kato M, Caja L, Heldin C-H, Moustakas A.
    • Journal Title

      J Cell Physiol.

      Volume: 238(4) Issue: 4 Pages: 790-812

    • DOI

      10.1002/jcp.30975

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K20597
  • [Journal Article] Promotion of squamous cell carcinoma tumorigenesis by oncogene‐mediated THG‐1/TSC22D4 phosphorylation2023

    • Author(s)
      Goto Nohara、Suzuki Hiroyuki、Zheng Ling、Okano Yasuhito、Okita Yukari、Watanabe Yukihide、Kato Yukinari、Kato Mitsuyasu
    • Journal Title

      Cancer Science

      Volume: 114 Issue: 10 Pages: 3972-3983

    • DOI

      10.1111/cas.15934

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15596, KAKENHI-PROJECT-22K06995, KAKENHI-PROJECT-20K20597
  • [Journal Article] TGFβ selects for pro-stemness over pro-invasive phenotypes during cancer cell epithelial-mesenchymal transition.2022

    • Author(s)
      Tsubakihara Y, Ohata Y, Okita Y, Younis S, Eriksson J, Sellin ME, Ren J, Ten Dijke P, Miyazono K, Hikita A, Imamura T, Kato M, Heldin CH, Moustakas A.
    • Journal Title

      Molecular Oncology

      Volume: 16 Issue: 12 Pages: 2330-2354

    • DOI

      10.1002/1878-0261.13215

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K20597
  • [Journal Article] Glycoprotein NMB promotes tumor formation and malignant progression of laryngeal squamous cell carcinoma2022

    • Author(s)
      Manevich L, Okita Y, Okano Y, Sugasawa T, Kawanishi K, Poullikkas T, Dang Cao LTL, Zheng L, Nakayama M, Matsumoto S, Tabuchi K, Kato M
    • Journal Title

      Cancer Science

      Volume: - Issue: 9 Pages: 3244-3254

    • DOI

      10.1111/cas.15359

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07658, KAKENHI-PROJECT-20K20597
  • [Journal Article] TGF-β-Induced TMEPAI Promotes Epithelial-Mesenchymal Transition in Doxorubicin-Treated Triple-Negative Breast Cancer Cells via SMAD3 and PI3K/AKT Pathway Alteration.2021

    • Author(s)
      Wardhani BWK, Louisa M, Watanabe Y, Setiabudy R, Kato M.
    • Journal Title

      Breast Cancer

      Volume: 13 Pages: 529-538

    • DOI

      10.2147/bctt.s325429

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K20597
  • [Journal Article] Polyvinyl alcohol scaffolds and supplementation support 3D and sphere culturing of human cancer cell lines by reducing apoptosis and promoting cellular proliferation2021

    • Author(s)
      Okita Yukari、Zheng Ling、Kawanishi Kunio、Miyoshi Hirotoshi、Yanagihara Kazuyoshi、Kato Mitsuyasu
    • Journal Title

      Genes to Cells

      Volume: 26(5) Issue: 5 Pages: 336-343

    • DOI

      10.1111/gtc.12843

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07658, KAKENHI-PROJECT-20K20597, KAKENHI-PROJECT-19K17730, KAKENHI-PROJECT-20K16434, KAKENHI-PROJECT-18H02676
  • [Journal Article] PMEPA1/TMEPAI Is a Unique Tumorigenic Activator of AKT Promoting Proteasomal Degradation of PHLPP1 in Triple-Negative Breast Cancer Cells2021

    • Author(s)
      Md Anwarul Haque, Mohammed Abdelaziz, Meidi Utami Puteri, Thanh Thao Vo Nguyen, Kosei Kudo, Yukihide Watanabe, Mitsuyasu Kato
    • Journal Title

      Cancers

      Volume: 13 Issue: 19 Pages: 4934-4934

    • DOI

      10.3390/cancers13194934

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06942, KAKENHI-PROJECT-20K20597
  • [Journal Article] Glycoprotein non-metastatic melanoma protein B functions with growth factor signaling to induce tumorigenesis through its serine phosphorylation2021

    • Author(s)
      Wang Chen、Okita Yukari、Zheng Ling、Shinkai Yasuhiro、Manevich Lev、Chin Jas M.、Kimura Tomokazu、Suzuki Hiroyuki、Kumagai Yoshito、Kato Mitsuyasu
    • Journal Title

      Cancer Science

      Volume: 112 Issue: 10 Pages: 4187-4197

    • DOI

      10.1111/cas.15090

    • NAID

      120007178942

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07473, KAKENHI-PROJECT-19K07658, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-20K20597
  • [Journal Article] PMEPA1/TMEPAI isoforms function via its PY and Smad interaction motifs for tumorigenic activities of breast cancer cells.2020

    • Author(s)
      Puteri MU, Watanabe Y, Wardhani BWK, Amalia R, Abdelaziz M, Kato M.
    • Journal Title

      Genes to Cells

      Volume: in press Issue: 6 Pages: 375-390

    • DOI

      10.1111/gtc.12766

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06682, KAKENHI-PROJECT-20K20597, KAKENHI-PROJECT-18H02676
  • [Journal Article] Role of the kringle-like domain in glycoprotein NMB for its tumorigenic potential.2019

    • Author(s)
      Xie R, Okita Y, Ichikawa Y, Fikry MA, Huynh Dam KT, Tran STP, Kato M
    • Journal Title

      Cancer Science

      Volume: 110 Issue: 7 Pages: 2237-2246

    • DOI

      10.1111/cas.14076

    • NAID

      120007133159

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07658, KAKENHI-PROJECT-18H02676
  • [Journal Article] Cell-surface GPNMB and induction of stemness.2018

    • Author(s)
      Okita Y, Chen C, Kato M.
    • Journal Title

      Oncotarget

      Volume: 9(99) Issue: 99 Pages: 37289-37290

    • DOI

      10.18632/oncotarget.26472

    • Open Access
    • Data Source
      KAKENHI-PROJECT-18H02676, KAKENHI-PROJECT-17K14981
  • [Journal Article] Glycoprotein nmb is exposed on the surface of dormant breast cancer cells and induces stem cell-like properties.2018

    • Author(s)
      Chen C, Okita Y, Watanabe Y, Abe F, Fikry MA, Ichikawa Y, Suzuki H, Shibuya A, Kato M.
    • Journal Title

      Cancer Research

      Volume: 78(22) Pages: 6424-6435

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02676
  • [Journal Article] The transcription factor MAFK induces EMT and malignant progression of triple-negative breast cancer cells through its target GPNMB2017

    • Author(s)
      Yukari Okita, Minori Kimura, Rudy Xie, Chen Chen, Larina Tzu-Wei Shen, Yurika Kojima, Hiroyuki Suzuki, Masafumi Muratani, Masao Saitoh, Kentaro Semba, Carl-Henrik Heldin, Mitsuyasu Kato
    • Journal Title

      Science Signaling

      Volume: 10 Issue: 474 Pages: 11-11

    • DOI

      10.1126/scisignal.aak9397

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19070, KAKENHI-PROJECT-16K08706, KAKENHI-PUBLICLY-15H01343, KAKENHI-PROJECT-15H05576
  • [Journal Article] Regulation of the TMEPAI promoter by TCF7L2: the C-terminal tail of TCF7L2 is essential to activate the TMEPAI gene2016

    • Author(s)
      Naoko Nakano, Mitsuyasu Kato & Susumu Itoh
    • Journal Title

      The journal of biochemistry

      Volume: 159 Issue: 1 Pages: 27-30

    • DOI

      10.1093/jb/mvv117

    • NAID

      120007129718

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K18866, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-26305006
  • [Journal Article] Cooperative induction of transmembrane prostate androgen induced protein TMEPAI/PMEPA1 by transforming growth factor-b and epidermal growth factor signaling.2015

    • Author(s)
      Azami S, Vo Nguyen TT, Watanabe Y, Kato M.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 456 Issue: 2 Pages: 580-585

    • DOI

      10.1016/j.bbrc.2014.11.107

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25870093, KAKENHI-PUBLICLY-26116707, KAKENHI-PROJECT-25293092
  • [Journal Article] C18ORF1: A Novel Negative Regulator of TGF-β Signaling.2014

    • Author(s)
      2. Nakano N, Maeyama K, Ikeno S, Itoh F, Togawa Y, Katsu Y, Thanh Thao, VN, Watanabe Y, Kato M & Itoh, S.
    • Journal Title

      J. Biol. Chem.,

      Volume: 289 Issue: 18 Pages: 12680-12680

    • DOI

      10.1074/jbc.m114.558981

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23689023, KAKENHI-PUBLICLY-25118728, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-25670168, KAKENHI-PROJECT-26305006, KAKENHI-PROJECT-26460479
  • [Journal Article] C18 ORF1: A Novel Negative Regulator of TGF-β Signaling.2014

    • Author(s)
      Nakano N, Maeyama K, Sakata N, Itoh F, Akatsu R, Nakata M, Katsu Y, Ikeno S, Togawa Y, Thanh Thao Vo Nguyen TT, Watanabe Y, Kato M and Itoh S.
    • Journal Title

      Jounal of Biological Chemistry

      Volume: 289

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293092
  • [Journal Article] TMEPAI/PMEPA1 enhances tumorigenic activities in lung cancer cells.2014

    • Author(s)
      3) Vo Nguyen TT, Watanabe Y, Shiba A, Noguchi M, Itoh S and Kato M.
    • Journal Title

      Cancer Sci.

      Volume: 105 Issue: 3 Pages: 334-341

    • DOI

      10.1111/cas.12355

    • NAID

      120007136725

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293092, KAKENHI-PUBLICLY-26116707, KAKENHI-PROJECT-26305006
  • [Journal Article] Transforming growth factor-&βinduces transcription factors MafK and Bach1 to suppress expression of the heme oxygenase-1 gene.2013

    • Author(s)
      Okita Y, Kamoshida A, Suzuki H, Itoh K, Motohashi H, Igarashi K, Ogami T, Koinuma D, Kato M.
    • Journal Title

      J Biol Chem

      Volume: 288 Issue: 28 Pages: 20658-20667

    • DOI

      10.1074/jbc.m113.450478

    • NAID

      120007136878

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-25460472, KAKENHI-PROJECT-25640059
  • [Journal Article] Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes2013

    • Author(s)
      Yoon JH, Sudo K, Kuroda M. (18 名 15 番目)
    • Journal Title

      EMBO molecular Medicine

      Volume: 5(11) Issue: 11 Pages: 1720-39

    • DOI

      10.1002/emmm.201302524

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23590417, KAKENHI-PROJECT-23659626, KAKENHI-PROJECT-24592039, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-25670197
  • [Journal Article] Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions.2012

    • Author(s)
      Itoh F, Itoh S, Adachi T, Ichikawa K, Matsumura Y, Takagi T, Festing M, Watanabe T, Weinstein M, Karlsson S and Kato M
    • Journal Title

      Blood.

      Volume: 119 Pages: 5320-5328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Journal Article] Delayed cutaneous wound healing in Fam129b/Minerva-deficient mice.2012

    • Author(s)
      Oishi H, Itoh S, Matsumoto K, Ishitobi H, Suzuki R, Ema M, Kojima T, Uchida K, Kato M, Miyata T and Takahashi S.
    • Journal Title

      J. Biochem.

      Volume: 152 Pages: 549-555

    • NAID

      10031166173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Journal Article] Interference of E2-2-mediated effect inendothelial cells by FAM96B through its limited expression of E2-2.2011

    • Author(s)
      Yang W, Itoh F, Ohya H, Kishimoto F, Tanaka A, Nakano N, Itoh S, Kato M
    • Journal Title

      Cancer Sci

      Volume: 102 Pages: 1808-1814

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Journal Article] TGF-β Signaling in Gingival Fibroblast-Epithelial Interaction.2010

    • Author(s)
      Ohshima M, Yamaguchi Y, Matsumoto N, Micke P, Takenouchi Y, Nishida T, Kato M, Komiyama K, Abiko Y, Ito K, Otsuka K and Kappert K.
    • Journal Title

      J Dent Res.

      Volume: 89 Pages: 1315-1321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Journal Article] TMEPAI, a transmembrane TGF-β-inducible protein,sequesters Smad proteins from active participation in TGF-β signaling2010

    • Author(s)
      Watanabe Y, Itoh S, GotoT, OhnishiE, InamitsuM, ItohF, SatohK, WiercinskaE, Yan gW, ShiL, TanakaA, NakanoN, MommaasAM, ShibuyaH, ten DijkeP and KatoM.
    • Journal Title

      Mol Cell.

      Volume: 37 Pages: 123-134

    • NAID

      120007138226

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Journal Article] Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis.2010

    • Author(s)
      Tanaka A, ItohF, TakezawaT, Itoh S and Kato M
    • Journal Title

      Blood

      Volume: 115 Pages: 4138-4147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Journal Article] Requirement of TCF7L2 for TGF-β-dependent transcriptional activation of the TMEPAI gene.2010

    • Author(s)
      Nakano N, Itoh S, Watanabe Y, Maeyama K, Itoh F, and Kato M.
    • Journal Title

      J Biol Chem.

      Volume: 285 Pages: 38023-38033

    • NAID

      120007137359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Journal Article] Poor Vessel Formation in Embryos from Knock-in Mice Expressing ALK5 with L45 Loop Mutation Defective in Smad Activation2009

    • Author(s)
      Itoh F, Itoh S, Carvalho RLC, Adachi T, Ema M, Goumans MJ, Larsson J, Karlsson S, Takahasi S, Mummery CL, ten Dijke P and Kato M
    • Journal Title

      Lab Invest.

      Volume: 89 Pages: 800-810

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Journal Article] TGF-β signaling and its regulatory mechanism.

    • Author(s)
      Susumu Itoh, Mitsuyasu Kato
    • Journal Title

      The Cell (Japanese) (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390073
  • [Patent] 画像処理システム、画像処理方法及び画像処理プログラム2012

    • Inventor(s)
      加藤 光保他
    • Industrial Property Rights Holder
      加藤 光保他
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-140594
    • Filing Date
      2012-06-22
    • Data Source
      KAKENHI-PUBLICLY-23114502
  • [Patent] 画像処理システム、画像処理方法及び画像処理プログラム2012

    • Inventor(s)
      加藤光保、他
    • Industrial Property Rights Holder
      加藤光保、他
    • Industrial Property Number
      2012-140594
    • Filing Date
      2012-06-22
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Patent] 新規なレポータープラスミド2007

    • Inventor(s)
      加藤光保, 他4名
    • Industrial Property Rights Holder
      筑波大学
    • Industrial Property Number
      2007-260613
    • Filing Date
      2007-10-04
    • Data Source
      KAKENHI-PROJECT-19406003
  • [Patent] 新規なレポータープラスミド2007

    • Inventor(s)
      加藤, 光保他
    • Industrial Property Rights Holder
      筑波大学
    • Filing Date
      2007-10-04
    • Data Source
      KAKENHI-PROJECT-18012009
  • [Presentation] GPNMB is c-mannosylated and works as a WNT5α receptor2023

    • Author(s)
      KATO Mitsuyasu
    • Organizer
      TGF-β meeting in Uppsala
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K20597
  • [Presentation] Correlation of GPNMB and FGFR1 in breast cancer2023

    • Author(s)
      Manar Elhinnawi; 沖田 結花里; 加藤光保
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K20597
  • [Presentation] 細胞運動性獲得におけるGPNMBの作用2023

    • Author(s)
      沖田結花理、加藤光保
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K20597
  • [Presentation] 幹細胞性誘導によるがんの持続的増殖機構2020

    • Author(s)
      加藤光保、沖田結花里
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K20597
  • [Presentation] 幹細胞性誘導によるがんの持続的増殖機構2020

    • Author(s)
      加藤光保
    • Organizer
      第109回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-18H02676
  • [Presentation] 幹細胞性誘導によるがん細胞の持続的増殖機構2019

    • Author(s)
      加藤光保、渡邊幸秀、沖田結花里、Meidi Utami Puteri、Mohammed Abdelaziz、市川優矛
    • Organizer
      第38回分子病理研究会
    • Data Source
      KAKENHI-PROJECT-18H02676
  • [Presentation] 幹細胞性誘導によるがん細胞の持続的増殖機構2019

    • Author(s)
      加藤光保
    • Organizer
      第108回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-18H02676
  • [Presentation] Screening of macrocyclic peptide against CD44.2019

    • Author(s)
      後藤のはら、Hipolito Chris、鈴木裕之、加藤光保
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02676
  • [Presentation] The roles of TMEPAI in breast cancer cells2018

    • Author(s)
      Meidi Utami Puteri, Bantari Wisynu Kusuma Wardhani, Riezki Amalia, Mohammed Abdelaziz, Yukihide Watanabe and Mitsuyasu Kato
    • Organizer
      The 3rd International Conference on Advance Pharmacy and Pharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02676
  • [Presentation] THG-1, a novel oncogene in tumor angiogenesis2018

    • Author(s)
      Ling Zheng, Hiroyuki Suzuki and Mitsuyasu Kato
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17K19580
  • [Presentation] The roles of TMEPAI in breast cancer cells2018

    • Author(s)
      Meidi Utami Puteri, Bantari Wisynu Kusuma Wardhani, Riezki Amalia, Mohammed Abdelaziz, Yukihide Watanabe and Mitsuyasu Kato
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H02676
  • [Presentation] 乳がん細胞の運動におけるGPNMBとFGF-2の作用2018

    • Author(s)
      市川優矛、沖田, 結花里、加藤光保
    • Organizer
      第107回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-18H02676
  • [Presentation] 幹細胞性誘導によるがん細胞の持続的増加機構2018

    • Author(s)
      加藤光保
    • Organizer
      第107回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-18H02676
  • [Presentation] Stemness induction as a mechanism of tumorigenic cancer cell growth2018

    • Author(s)
      Mitsuyasu Kato
    • Organizer
      The 3rd International Conference on Advance Pharmacy and Pharmaceutical Sciences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02676
  • [Presentation] 乳がんの発生・進展におけるGPNMBの役割2016

    • Author(s)
      沖田結花里、鈴木裕之、加藤光保
    • Organizer
      第105回日本病理学会総会
    • Place of Presentation
      宮城県仙台市、仙台国際交流センター
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] 乳がんの発生・進展におけるGPNMBの役割2016

    • Author(s)
      沖田結花里、鈴木裕之、加藤光保
    • Organizer
      第105回日本病理学会総会
    • Place of Presentation
      仙台国際センター 宮城県 仙台市
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] Roles of GPNMB in breast cancer initiation and malignant progression2016

    • Author(s)
      Yukari Okita, Ai Kato, Chen Chen, Hiroyuki Suzuki, and Mitsuyasu Kato
    • Organizer
      the 41st Naito Conference
    • Place of Presentation
      シャトレーゼ ガトーキングダム サッポロ 北海道 札幌市
    • Year and Date
      2016-07-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] Roles of GPNMB in breast cancer malignant formation and progression2016

    • Author(s)
      Yukari Okita, Hiroyuki Suzuki, and Mitsuyasu Kato
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜 神奈川県 横浜市
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] 乳がんにおけるGPNMBの役割2016

    • Author(s)
      沖田結花里、陳晨、鈴木裕之、加藤光保
    • Organizer
      第39回分子生物学会年会
    • Place of Presentation
      パシフィコ横浜 神奈川県 横浜市
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] Roles of GPNMB in Breast Cancer Stem Cells2016

    • Author(s)
      陳晨、沖田結花里、加藤光保
    • Organizer
      第39回分子生物学会年会
    • Place of Presentation
      パシフィコ横浜 神奈川県 横浜市
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] 転写因子MafKはTGF-βによって誘導され、腫瘍形成を促進する2016

    • Author(s)
      加藤光保、沖田結花里
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜 神奈川県 横浜市
    • Year and Date
      2016-10-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] Transcription factor MafK induces epithelial-mesenchymal transition and malignant progression of breast cancer cells.2015

    • Author(s)
      Yukari Okita, Hiroyuki Suzuki and Mitsuyasu Kato
    • Organizer
      FASEB Science Research Conference
    • Place of Presentation
      Snowmass, Colorado
    • Year and Date
      2015-07-12
    • Data Source
      KAKENHI-PROJECT-25293092
  • [Presentation] 腫瘍の血管新生におけるTHG-1/Tsc22D4の役割2015

    • Author(s)
      LING ZHENG、鈴木裕之、加藤光保
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25293092
  • [Presentation] 乳がんにおける転写因子MafKの働き2015

    • Author(s)
      沖田結花里、鈴木裕之、加藤光保
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      愛知県名古屋市、名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] Roles of MafK and Gpnmb in tumor development2015

    • Author(s)
      Mitsuyasu Kato
    • Organizer
      TGF-beta meeting 2015
    • Place of Presentation
      Uppsala, Sweden
    • Year and Date
      2015-08-20
    • Data Source
      KAKENHI-PUBLICLY-26116707
  • [Presentation] 乳腺上皮細胞の上皮間葉転換と腫瘍形成における転写因子MafKの役割2015

    • Author(s)
      加藤光保
    • Organizer
      第34回分子病理学研究会
    • Place of Presentation
      神戸ホテルフルーツ・フラワー 神戸市
    • Year and Date
      2015-07-25
    • Data Source
      KAKENHI-PUBLICLY-26116707
  • [Presentation] 乳癌の発生におけるMafK/GPNMBの作用2015

    • Author(s)
      加藤光保
    • Organizer
      新学術研究班会議
    • Place of Presentation
      菊南温泉ユウベルホテル 熊本市
    • Year and Date
      2015-06-14
    • Data Source
      KAKENHI-PUBLICLY-26116707
  • [Presentation] Transcription factor MafK induces epithelial-mesenchymal transition and malignant progression of breast cancer cells2015

    • Author(s)
      Yukari Okita, Hiroyuki Suzuki, and Mitsuyasu Kato
    • Organizer
      FASEB meeting The TGF-β Superfamily: Signaling in Development and Disease
    • Place of Presentation
      アメリカ合衆国コロラド州
    • Year and Date
      2015-07-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] ADPリボース化によるBMPシグナルの制御2015

    • Author(s)
      渡邊幸秀、Aristidis Moustakas、加藤光保
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25293092
  • [Presentation] 乳がんにおける転写因子MafKの働き2015

    • Author(s)
      沖田結花里、鈴木裕之、加藤光保
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25293092
  • [Presentation] Roles of MafK and Gpnmb in tumor development.2015

    • Author(s)
      Mitsuyasu Kato
    • Organizer
      TGF-β meeting 2015
    • Place of Presentation
      Uppsala, Sweden
    • Year and Date
      2015-08-20
    • Data Source
      KAKENHI-PROJECT-25293092
  • [Presentation] 大腸腫瘍の発生に置ける間欠性増殖細胞の動態に関する研究2015

    • Author(s)
      加藤光保
    • Organizer
      第104回日本病理学会総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-04-30
    • Data Source
      KAKENHI-PROJECT-25293092
  • [Presentation] Tumorigenic activities of TGF-β Target Genes TMEPAI and MafK2013

    • Author(s)
      Mitsuyasu Kato
    • Organizer
      TGF-β meeting in Uppsala
    • Place of Presentation
      Uppsala, Sweden
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293092
  • [Presentation] 細胞増殖、分化、癌化におけるTsc-22ファミリー分子の役割2013

    • Author(s)
      鈴木裕之、加藤光保
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-25640059
  • [Presentation] Tumorigenic activity of TMEPAI and MafK2013

    • Author(s)
      Mitsuyasu Kato
    • Organizer
      The 3rd International Symposium by JSPS Core-to-Core Program “Cooperative International Framework in TGF-β Family Signaling”
    • Place of Presentation
      松山
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293092
  • [Presentation] がんの発生と進展における トランスフォーミング増殖因子β の作用2013

    • Author(s)
      加藤光保
    • Organizer
      第10回日本病理学会カンファレンス
    • Place of Presentation
      神戸
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293092
  • [Presentation] Intermittently proliferating Geyser cells in the colonic mucosa2012

    • Author(s)
      Mitsuyasu Kato
    • Organizer
      LICR TGF-beta meeting
    • Place of Presentation
      Leiden (the Netherlands)
    • Year and Date
      2012-08-29
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-23114502
  • [Presentation] TMEPAI in Cancer Cell Biology2012

    • Author(s)
      Mitsuyasu Kato
    • Organizer
      The1^<st>International Symposium by JSPS Core-to-Core Program "Cooperative International Framework in TGF-β Family Signaling"
    • Place of Presentation
      University of Tokyo, Tokyo
    • Year and Date
      2012-01-23
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Presentation] 3次元定量組織学解析による発がんメカニズムの研究2012

    • Author(s)
      加藤光保
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      東京
    • Year and Date
      2012-04-26
    • Data Source
      KAKENHI-PUBLICLY-23114502
  • [Presentation] TMEPAI in Cancer Cell Biology2012

    • Author(s)
      Kato M.
    • Organizer
      The 1^<st> International Symposium by JSPS Core-to-Core Program "Cooperative International Framework in TGF-β Family Signaling"
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2012-01-23
    • Data Source
      KAKENHI-PUBLICLY-23114502
  • [Presentation] TMEPAI in Cancer Cell Biology2012

    • Author(s)
      Kato M.
    • Organizer
      The 1^<st> International Symposium by JSPS Core-to-Core Program "Cooperative International Framework in TGF-β Family Signaling"
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2012-01-23
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Presentation] Smad traps, TMEPAI and C18ORF1 are negative regulators of TGF-β signaling2011

    • Author(s)
      Kato M.
    • Organizer
      The First Bonn-Tsukuba Symposium in Medicine
    • Place of Presentation
      つくば(招待講演)
    • Year and Date
      2011-11-03
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Presentation] Role of Smad4 in Cellular Turnover of Colonic Mucosa2011

    • Author(s)
      Kato M.
    • Organizer
      LICR TGF-β meeting in Uppsala
    • Place of Presentation
      Uppsala, Sweden(招待講演)
    • Year and Date
      2011-08-18
    • Data Source
      KAKENHI-PUBLICLY-23114502
  • [Presentation] Role of Smad4 in Cellular Turnover of Colonic Mucosa2011

    • Author(s)
      Kato M.
    • Organizer
      LICR TGF-β meeting in Uppsala
    • Place of Presentation
      Uppsala, Sweden(招待講演)
    • Year and Date
      2011-08-18
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Presentation] 大腸腺種の発生におけるWntシグナルの機能の3次元定量組織学による解析2011

    • Author(s)
      Kato M
    • Organizer
      平成22年度「個体レベルでのがん研究支援活動」 ワークショップ
    • Place of Presentation
      大津
    • Year and Date
      2011-02-04
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Presentation] Smad traps, TMEPAI and C18ORF1 are negative regulators of TGF-β signaling2011

    • Author(s)
      Kato M.
    • Organizer
      The First Bonn-Tsukuba Symposium in Medicine
    • Place of Presentation
      つくば(招待講演)
    • Year and Date
      2011-11-03
    • Data Source
      KAKENHI-PUBLICLY-23114502
  • [Presentation] Smad traps for negative regulation of TGF-β signaling2010

    • Author(s)
      Mitsuyasu Kato
    • Organizer
      The 59th Fujihara International Seminar
    • Place of Presentation
      Grand Hotel New Oji, Tomakomai
    • Year and Date
      2010-07-15
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Presentation] 新規TGF-β関連分子のがんにおける機能2010

    • Author(s)
      加藤光保
    • Organizer
      革新的医薬シーズ 開発研究シンポジウム
    • Place of Presentation
      筑波大学先端学際領域研究(TARA)センター, つくば
    • Year and Date
      2010-06-22
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Presentation] TGF-beta stimulated clone-22 domain family 4(TSC22D4)is a novel oncogene activated in squamous cell carcinoma.2010

    • Author(s)
      Kato M
    • Organizer
      TGF-β meeting
    • Place of Presentation
      Leiden(オランダ)
    • Year and Date
      2010-09-03
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Presentation] TGF-beta stimulated clone-22 domain family 4 (TSC22D4) is a novel oncogene activated in squamous cell carcinoma2010

    • Author(s)
      Mitsuyasu Kato
    • Organizer
      TGF-β meeting
    • Place of Presentation
      Leiden University of Medical Center, Leiden, The Netherlands
    • Year and Date
      2010-09-03
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Presentation] Systematic pathological analysis and data capture in the Japan mouse clinic.2010

    • Author(s)
      Kato M
    • Organizer
      Pathology of the laboratory mouse
    • Place of Presentation
      Bordeaux(フラン条)
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Presentation] Smad traps for negative regulation of TGF-β signaling.2010

    • Author(s)
      Kato M
    • Organizer
      The 59th Fujihara International Seminar
    • Place of Presentation
      Tomakomai(北海道)
    • Year and Date
      2010-07-15
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Presentation] 新規TGF-β関連分子のがんにおける機能2010

    • Author(s)
      Kato M
    • Organizer
      革新的医薬シーズ開発研究シンポジウム
    • Place of Presentation
      つくば
    • Year and Date
      2010-06-22
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Presentation] TGF-β related genes in early carcinogenesis2009

    • Author(s)
      Kato M
    • Organizer
      International Symposium on TGF-β signaling, Inflammation, and Cancer Prevention
    • Place of Presentation
      Inchon(Korea)
    • Year and Date
      2009-11-20
    • Data Source
      KAKENHI-PROJECT-20012007
  • [Presentation] TGF-β related genes in early carcinogenesis2009

    • Author(s)
      Kato M
    • Organizer
      International Symposium on TGF-β signaling, Inflammation, and Cancer Prevention
    • Place of Presentation
      Inchon(Korea)
    • Year and Date
      2009-11-20
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Presentation] TGF-β related genes in early carcinogenesis2009

    • Author(s)
      Mitsuyasu Kato
    • Organizer
      International Symposium on TGF-β signaling, Inflammation, and Cancer Prevention
    • Place of Presentation
      Gachon University of Medicine and Science, Incheon, Korea.
    • Year and Date
      2009-11-20
    • Data Source
      KAKENHI-PROJECT-21390115
  • [Presentation] TMEPAI makes a novel negative feedback loop of TGF-f3 signaling2008

    • Author(s)
      Mitsuyasu Kato
    • Organizer
      The 28th Sapporo Cancer Seminar International Symposium
    • Place of Presentation
      Sapporo
    • Year and Date
      2008-06-26
    • Data Source
      KAKENHI-PROJECT-20012007
  • [Presentation] Tsc-22 and TMEPAI: target genes of TGF-β signaling possibly involved in cancer development2007

    • Author(s)
      Kato, M, et. al.
    • Organizer
      第66回日本癌学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18012009
  • [Presentation] Tsc-22 and TMEPAI: target genes of TGF-β signaling possibly involved in cancer development2007

    • Author(s)
      M. Kato, et. al.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19406003
  • [Presentation] Ephrin-A1 promotes the malignant progression of intestinal tumors in Apcmin/+ mice.2007

    • Author(s)
      Shi, L, Kato, M
    • Organizer
      第24回日本疾患モデル学会総会
    • Place of Presentation
      つくば
    • Data Source
      KAKENHI-PROJECT-18012009
  • [Presentation] TMEPAI blocks TGF-β Smad pathway2007

    • Author(s)
      Itoh, S, Kato, M
    • Organizer
      第66回日本癌学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18012009
  • [Presentation] Tsc-22; a dual target mediator of TGF-b-induced growth inhibition2007

    • Author(s)
      M. Kato
    • Organizer
      TGF-β meeting in Uppsala
    • Place of Presentation
      Uppsala, Sweden
    • Data Source
      KAKENHI-PROJECT-19406003
  • [Presentation] 足場非依存性間欠性細胞分裂の転写制御と代謝

    • Author(s)
      加藤光保
    • Organizer
      生命素子による転写環境とエネルギー代謝のクロストーク制御(転写代謝システム)班会議
    • Place of Presentation
      仙台
    • Year and Date
      2014-07-11 – 2014-07-13
    • Data Source
      KAKENHI-PUBLICLY-26116707
  • 1.  MIYAZONO Kohei (90209908)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  KAWABATA Masahiro (60224838)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 3.  ICHIJO Hidenori (00242206)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 4.  IMAMURA Takeshi (70264421)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  NOSE Masato (70030913)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  SUZUKI Hiroyuki (70375509)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 7.  MURAKAMI Kazuhiro (90190876)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  HANAI Jun-ichi (70261964)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  OKITA Yukari (30743710)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 16 results
  • 10.  井上 博文 (70321635)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  KANAHO Yasunori (00214437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KUMAGAI Yoshito (00250100)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  NAGATA Kyosuke (40180492)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  OHNEDA Osamu (30311872)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  WATANABE Yukihide (40618534)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 16.  ISHIDOU Yasuhiro (10300740)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MIYAZAWA Keiji (40209896)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  WATABE Tetsuro (00334235)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  SAITOH Masao (90345041)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  ITOH Susumu (70223154)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 21.  KYOGOKU Masahisa (70025542)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  SAWAI Takashi (00125577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  宮沢 正顕 (60167757)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  Hipolito Christopher John
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  中野 なおこ
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  伊東 史子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  鄭 齢
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  本橋 ほづみ
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  須藤 カツ子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  黒田 雅彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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