MUTSUNORI SHIRAI 白井睦訓

… Alternative Names

SHIRAI Mutsunori 白井睦訓

白井睦訓シライムツノリ

白井陸訓シライムツノリ

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Researcher Number	20196596
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2019 – 2021: 山口大学, 大学院医学系研究科, 教授 2017: 山口大学, 大学院医学系研究科, 教授 2015 – 2017: 山口大学, 医学(系)研究科(研究院), 教授 2009 – 2010: Yamaguchi University, 大学院・医学系研究科, 教授 2000 – 2004: yamaguchi University, School of Medicine, Professor., 医学部, 教授 … More 1995 – 1999: Yamaguchi University School of Medicine, Associate Professor, 医学部, 助教授 1993: 香川医科大学, 医学部・附属病院, 助手 1987 – 1989: 香川医科大学, 医学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Gastroenterology / Infectious disease medicine / Basic Section 53010:Gastroenterology-related / Complex systems / Virology / Gastroenterology / Cerebral neurosurgery Except Principal Investigator Gastroenterology / Bacteriology (including Mycology) / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords	Principal Investigator 感染 / クラミジア / ゲノム / HCV / MHC / peptide / Antibody / T cell / シグナル伝達 / 動脈硬化 … More / 肺炎クラミジア / ペプチド / ワクチン / C型肝炎 / YAPシグナル / Th1 / COX-2 / サイトカイン / cJun / JNK / Virus / Vaccine / Hepatitis C / アポトーシス / ヘリコバクター・ピロリ / 除菌療法 / 消化性潰瘍 / ペニシリン結合タンパク / 薬剤耐性 / ペニシリン / アモキシシリン / 感染免疫 / 細胞外マトリックス / 細菌 / 抗体 / T細胞 / 免疫 / 腸炎 / IL8 / IL-8 / サルモネラ / MST1/2 / Hippo経路 / ribD / Francisella tularensis / MAIT cell / Hippo / YAP / シグナル伝達系 / 宿主-病原体 / 微小重力 / 細菌感染 / メダカ / オルガノイド / 微小重力環境 / 病原体 / Cytokine / MAP kinase / Signal transduction / Helicobacter pylori / ヘリコバクターピロリ / プロテインキナーゼ / 肝癌 / 胃癌 / MPAキナーゼ / CTL / Vaccinia / pepticle / virus / vaccine / hepatitis C / 封入体 / ミトコンドリア / 感染症 / 平滑筋 / 相互作用解析 / H. Pylori / Helicobacter / 抗生物質 / 薬剤耐性菌 / PBP / アモキシリン / DNAマイクロアレイ / 遺伝子 / ゲノム情報 / アレイ / 結核 / SET / two-hybrid / 心筋梗塞 / 微生物 / DNAマイクロアレー / DNAチップ / mRNA / 転写 / RT-PCR / マイクロアレー / Chlamydia pneumoniae / C.pneumoniae / 転写因子 / 宿主応答 / NFκB / インドメサシン / NSAIDS / cyclooxygenase / プロスタグランジン / アスピリン / Cox 2 / NK-κB / gp160 / エイズ / T細胞レセプター … More Except Principal Investigator HBV / B型肝炎 / 慢性活動性肝炎 / オルガノイド / 力学特性 / YAP / がん免疫 / 免疫チェックポイント療法 / リンパ節 / Electron microscopy / Post-tranfusion hepatitis / NonA, NonB hepatitis / ウィスル様粒子 / 非A非B型肝炎 / 核内粒子 / ウィルス様粒子 / 電子顕微鏡的観察 / 輸血後肝炎 / 非A非B肝炎 / Hepatitis B / Chronic Active Hepatitis / IL2 / DNA polymerase / lymphokine activated Killer 細胞 / Natural Killer 細胞 / recombinant interlenkin 2 / lymphokine activated killer細胞 / IL-2, Natural Killer細胞 / トランスアミナーゼ / DNAポリメラーゼ / 免疫賦活療法 / lymphokine avivated killer細胞 / Natural killer細胞 / IL-2 / recombinant IL-2 / transcription analysis / CTL induction / cell-division-related gene / sigma factor / coccoid form / urease / H.pylori infection / 尿素 / ヘリコバクター・ピロリ / 転写開始点 / 走化性 / ヘリコバクター・ピロリ感染 / 転写解析 / CTL誘導 / 細胞分裂関連遺伝子 / シグマ因子 / 球状体 / ウレアーゼ / ヘリコバクターピロリ感染 / Interleukin-2 / Interferon / Anti-viral therapy / Lymphokine-activated killer cells / Natural killer cells / Chronic active hepatitis / HB core antigen / Hepatitis B virus / T細胞 / リンパ球 / Pre Sz抗原 / HBC抗原 / インタ-ロイキンz / インタ-ロイキン2 / インタ-フェロン / 抗ウイルス療法 / LAK細胞 / NK細胞 / HBc抗原 / B型肝炎ウイルス(HBV) / NFKB / リンホトキシン / TNF / NO / I-kBα / NF-kB / 動脈硬化 / Chlamydia pneumonia Less

Creation of lyph node organoids enabling mechanical control of immunity
- Principal Investigator
  
  Seiki Makoto
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Yamaguchi University
3D intestinal development and carcinogenesis by Hippo-YAP pathwayPrincipal Investigator
- Principal Investigator
  
  MUTSUNORI SHIRAI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yamaguchi University
微小重力環境における宿主-病原体の相互作用変化をもたらす分子基盤の解明Principal Investigator
- Principal Investigator
  
  白井睦訓
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Yamaguchi University
Search for a novel anti-pathogen defense system by studying host-pathogen interactionsPrincipal Investigator
- Principal Investigator
  
  SHIRAI Mutsunori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Yamaguchi University
細胞内寄生性細菌の新たな宿主アポトーシス制御因子の発見とその増殖調節機構の解明Principal Investigator
- Principal Investigator
  
  白井睦訓
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Yamaguchi University
動脈硬化に関連した動脈壁平滑筋炎症制御因子のゲノム網羅的探索Principal Investigator
- Principal Investigator
  
  白井睦訓
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yamaguchi University
病原微生物および宿主の違いによる感染の感受性と特異性の発現機構の解明Principal Investigator
- Principal Investigator
  
  白井睦訓
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yamaguchi University
アモキシシリン耐性ヘリコバクター・ピロリ菌の耐性機構解明とその診断・治療法の開発Principal Investigator
- Principal Investigator
  
  白井睦訓
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
新たな動脈壁平滑筋炎症制御因子の発現による動脈硬化の成因の解明Principal Investigator
- Principal Investigator
  
  白井睦訓
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yamaguchi University
病原微生物および宿主の違いによる感染の感受性と特異性の発現機構の解明Principal Investigator
- Principal Investigator
  
  白井睦訓
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yamaguchi University
肺炎クラミジア感染宿主細胞の網羅的遺伝子発現プロフィールの解析Principal Investigator
- Principal Investigator
  
  白井睦訓
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Yamaguchi University
全ゲノム情報に基づいた肺炎クラミジアの病原性遺伝子転写調節の統合的解明Principal Investigator
- Principal Investigator
  
  白井睦訓
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Yamaguchi University
肺炎クラミジア菌感染症による脳・頚動脈の動脈硬化進展機構の解明Principal Investigator
- Principal Investigator
  
  白井睦訓
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Yamaguchi University
Involvement of Helicaobacter pylori and hepatitis C virus in the crosstalk toward hepato-gastro carcinogenesis.Principal Investigator
- Principal Investigator
  
  SHIRAI Mutsunori
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
Chlamydia pneumoniaeの持続感染機構と動脈硬化発症機構の解明
- Principal Investigator
  
  NAKAZAWA Teruko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Yamaguchi University
Studies on the pathogenic factors of Helicobacter pylori.
- Principal Investigator
  
  NAKAZAWA Teruko
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Yamaguchi University
Development of killer T cell vaccine against HCV env HVRIPrincipal Investigator
- Principal Investigator
  
  SHIRAI Mutsunori
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Yamaguchi University
エイズウイルスgp160特異的キラー細胞及び抗体誘導ペプチドワクチンPrincipal Investigator
- Principal Investigator
  
  白井陸訓
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yamaguchi University
Peptide vaccine for killer T cell induction against hepatitis C virusPrincipal Investigator
- Principal Investigator
  
  SHIRAI Mutsunori
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
  香川医科大学
C型肝炎ウイルス特異的T細胞レセプターの解析Principal Investigator
- Principal Investigator
  
  白井睦訓
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  香川医科大学
Immunopathology and therapy of chronic active hepatitis type B
- Principal Investigator
  
  NISHIOKA Mikio
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagawa Medical School
Electron microscopic study of nonA, nonB hepatitis
- Principal Investigator
  
  WATANABE Seishiro
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagawa Medical School
Immunopathology and therapy of chronic active hepatitis type B
- Principal Investigator
  
  NISHIOKA Mikio
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagawa Medical School

All 2022 2017 2016 2015 2010 2009 2004

All Journal Article Presentation Patent

[Journal Article] An intracellular pathogen Francisella tularensis escapes from host immunity by metabolic reprogramming.2022
- Author(s)
  Kensuke Shibata, Takashi Shimizu, Mashio Nakahara, Francois Legoux,Sho Yamasaki, Makoto Furutani-Seiki, Olivier Lantz, Masahisa Watarai, Mutsunori Shirai
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 印刷中
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08424
[Journal Article] Development of a Novel Loop-Mediated Isothermal Amplification (LAMP) Assay for the Detection of <i>Rickettsia</i> spp.2017
- Author(s)
  Hanaoka N, Matsutani M, Satoh M, Ogawa M, Shirai M, Ando S
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 70 Issue: 1 Pages: 119-123
- DOI
  10.7883/yoken.JJID.2015.579
- NAID
  130005296301
- ISSN
  1344-6304, 1884-2836
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01644, KAKENHI-PROJECT-15K09568
[Journal Article] Overexpression of RhoH Permits to Bypass the Pre-TCR Checkpoint.2015
- Author(s)
  Tamehiro N, Oda H, Shirai M, Suzuki H.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 6 Pages: e0131047-e0131047
- DOI
  10.1371/journal.pone.0131047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09568, KAKENHI-PROJECT-25460606, KAKENHI-PROJECT-25871164
[Journal Article] An epistatic effect of apaf-1 and caspase-9 on chlamydial infection.2015
- Author(s)
  Rahman MA, Shirai M, Aziz MA, Ushirokita R, Kubota S, Suzuki H, Azuma Y.
- Journal Title
  
  Apoptosis
  
  Volume: 20 Issue: 10 Pages: 1271-1280
- DOI
  10.1007/s10495-015-1161-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09568, KAKENHI-PROJECT-15K15135
[Journal Article] Adaptive mutation related to cellulose producibility in Komagataeibacter medellinensis (Gluconacetobacter xylinus) NBRC 3288.2015
- Author(s)
  Matsutani M, Ito K, Azuma Y, Ogino H, Shirai M, Yakushi T, Matsushita K.
- Journal Title
  
  Appl Microbiol Biotechnol
  
  Volume: 99 Issue: 17 Pages: 7229-7240
- DOI
  10.1007/s00253-015-6598-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09568, KAKENHI-PROJECT-15K15135, KAKENHI-PROJECT-26660068, KAKENHI-PROJECT-26830126, KAKENHI-PROJECT-26860768
[Journal Article] Color-coded real-time cellular imaging of lung T-lymphocyte accumulation and focus formation in a mouse asthma model.2010
- Author(s)
  Hasegawa A.、 Shirai M., 他
- Journal Title
  
  J Allergy Clin Immunol.
  
  Volume: 125 Pages: 461-486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591293
[Patent] 標的RNAの検出・定量方法及びキット2010
- Inventor(s)
  白井睦訓
- Industrial Property Rights Holder
  山口大学
- Filing Date
  2010-09-15
- Overseas
- Data Source
  KAKENHI-PROJECT-21591293
[Patent] 新規核酸、及び当該核酸を用いたスクリーニング方法(クラミジアゲノム情報とその利用の特許)2004
- Inventor(s)
  白井睦訓(他4名, 1番目)
- Industrial Property Rights Holder
  山口大学
- Industrial Property Number
  2004-183135
- Filing Date
  2004-06-25
- Data Source
  KAKENHI-PROJECT-15659172
[Patent] 新規核酸、及び当該核酸を用いたスクリーニング方法(クラミジアゲノム情報とその利用の特許)2004
- Inventor(s)
  白井睦訓(他4名, 1番目)
- Industrial Property Rights Holder
  山口大学
- Industrial Property Number
  2004-183135
- Filing Date
  2004-06-25
- Data Source
  KAKENHI-PROJECT-16012245
[Presentation] 宇宙環境における宿主-病原体の相互作用の解析に向けた感染モデルの構築2017
- Author(s)
  浅岡洋一，荻野英賢, 白井睦訓
- Organizer
  第70回日本細菌学会中国・四国支部総会
- Data Source
  KAKENHI-PUBLICLY-16H01644
[Presentation] 宇宙環境における宿主-病原体の相互作用の解析に向けた感染モデルの構築2017
- Author(s)
  浅岡洋一，荻野英賢, 白井睦訓
- Organizer
  第70回日本細菌学会中国・四国支部総会
- Data Source
  KAKENHI-PROJECT-15K09568
[Presentation] 宇宙環境における宿主-病原体の相互作用変化の解析に向けたメダカ感染モデルの構築2016
- Author(s)
  浅岡洋一, 白井睦訓
- Organizer
  第86回日本感染症学会西日本地方会学術集会
- Place of Presentation
  沖縄県宜野湾市 (沖縄コンベンションセンター)
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-15K09568
[Presentation] 宇宙環境における宿主-病原体の相互作用変化の解析に向けたメダカ感染モデルの構築2016
- Author(s)
  浅岡洋一, 白井睦訓
- Organizer
  第86回日本感染症学会西日本地方会学術集会
- Data Source
  KAKENHI-PUBLICLY-16H01644
[Presentation] 感染・炎症制御のしくみ～ひとつの新しい捉え方2009
- Author(s)
  白井睦訓
- Organizer
  第22回日本外科感染症学会総会
- Place of Presentation
  宇部
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21591293

1. WATANABE Seishiro (00158635)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. 三浦公志郎 (30284243)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. NAKAZAWA Teruko (40053053)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. NISHIOKA Mikio (30034937)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TERADA Soichiro (40163919)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ASAOKA Yoichi (10436644)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. Seiki Makoto (50226619)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 東慶直 (90333509)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 柴田健輔 (50529972)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. NAKATSU Toshiaki (70198133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ARIMA Keiji (50212650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YOSHIYAMA Hironori (10253147)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MIZOTE Tomoko (90145938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KAGAWA Hiroyuki (70169382)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 永野浩昭 (10294050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 硲彰一 (50253159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MUTSUNORI SHIRAI 白井 睦訓

SHIRAI Mutsunori 白井 睦訓

白井 睦訓 シライ ムツノリ

白井 陸訓 シライ ムツノリ

Research Projects

Research Products

Co-Researchers

Creation of lyph node organoids enabling mechanical control of immunity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

3D intestinal development and carcinogenesis by Hippo-YAP pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

微小重力環境における宿主-病原体の相互作用変化をもたらす分子基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Search for a novel anti-pathogen defense system by studying host-pathogen interactionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細胞内寄生性細菌の新たな宿主アポトーシス制御因子の発見とその増殖調節機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

動脈硬化に関連した動脈壁平滑筋炎症制御因子のゲノム網羅的探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

病原微生物および宿主の違いによる感染の感受性と特異性の発現機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

アモキシシリン耐性ヘリコバクター・ピロリ菌の耐性機構解明とその診断・治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新たな動脈壁平滑筋炎症制御因子の発現による動脈硬化の成因の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

病原微生物および宿主の違いによる感染の感受性と特異性の発現機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肺炎クラミジア感染宿主 細胞の網羅的遺伝子発現プロフィールの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

全ゲノム情報に基づいた肺炎クラミジアの病原性遺伝子転写調節の統合的解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肺炎クラミジア菌感染症による脳・頚動脈の動脈硬化進展機構の解明Principal Investigator

MUTSUNORI SHIRAI 白井睦訓

SHIRAI Mutsunori 白井睦訓

白井睦訓シライムツノリ

白井陸訓シライムツノリ

肺炎クラミジア感染宿主細胞の網羅的遺伝子発現プロフィールの解析Principal Investigator