Nishiyama Nobuyoshi 西山信好

… Alternative Names

西山信好ニシヤマノブヨシ

NISHIYAMA Nobuyoshi 西山信好

Less

Researcher Number	20201692
Affiliation (Current)	2025: 兵庫医科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 兵庫医科大学, 薬学部, 教授 2021: 兵庫医療大学, 薬学部, 教授 2008 – 2010: 兵庫医療大学, 薬学部, 教授 1998 – 2001: Graduate School of Pharmaceatical Sciences, The University of Tokyo, Associate Professor, 大学院・薬学系研究科, 助教授 2000: 東京大学, 大学院・薬学研究科, 助教授 1997: 東京大学, 大学院・薬学系研究科, 助手 1994 – 1995: 東京大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Science and Engineering / Neuroscience in general Except Principal Investigator Basic Section 47040:Pharmacology-related / 応用薬理学・医療系薬学 / Biological pharmacy / Biological Sciences
Keywords	Principal Investigator 海馬 / ATP / arachidonic acid / ischemia / excitotoxicity / microglia / cultured hippocampal slice / interleukin-1 / 培養 / 神経細胞 … More / アラキドン酸 / 脳虚血 / 興奮毒性 / マイクログリア / 培養海馬切片 / インターロイキン1 / Cell Death / Brain Neuron / Purinergic Agents / 低血糖 / 虚血 / 細胞死 / 脳神経 / プリン / 中枢神経機能障害 / ライトトラッキング試験 / 3-レバーオペラント試験 / ビスフェノールA / プラーク形成試験 / 空間認知試験 / 能動的回避試験 / 受動的回避試験 / 記憶・学習 / 神経-免疫-内分泌機構 … More Except Principal Investigator 海馬 / 扁桃体 / 長期増強 / pharmacotherapy / drug abuse / drug dependence / histamine / methamphetamine / 組織含量 / 薬物療法 / 依存 / 中枢ヒスタミン神経 / ヒスタミン / GSK3 / ヒスタミンH1受容体 / Wnt/beta-cateninシグナル / GSK3阻害薬 / PI3K阻害薬 / ヒスタミンH3受容体 / 退薬症状 / 陽性症状 / PI3K経路 / GSK3経路 / モルヒネ / 覚せい剤 / ヒスタミン神経系 / 薬物依存 / Epilepsy / Axonal Branching / Interleukin-6 / Hippocampus / Cultured Neuron Cell / Interleukin-2 / Spermine / Polyamines / スペルミジン / プトレシン / インターロイキン6 / インターロイキン2 / 神経突起再生 / 成長円錐 / 軸索 / てんかん / 軸索分岐 / インターロイキン-6 / 培養神経細胞 / インターロイキン-2 / スペルミン / ポリアミン / ENT / CNT / ヌクレオシド輸送体 / DNAポリメラーゼβ / DNA修復酵素 / 過酸化水素 / 酸化ストレス / アストロサイト / 神経栄養因子 / 迷路学習 / 長期抑圧 / 脳弓海馬采 / 空間学習 / ホスホリパーゼ / ドコサヘキサエン酸 / シプナス可塑性 / ヘテロシナプス長期増強 / NMDA型受容体 / 亜鉛 / 海馬CA3野 / 容量性Caチャネル / 時空間的調節 / 歯状回 / BCM曲線 / 時空間依存性調節 / ヘテロシナプス / シナプス可塑性 / 記憶・学習 / 記憶 / 学習 Less

Modulation of histaminergic neurotransmission and pharmacotherapy for drug abuse and dependence
- Principal Investigator
  
  Kitanaka Junichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Hyogo Medical University
  Hyogo University of Health Sciences
The change of DNA repair enzymes and nucleoside transoprters by oxydative stress in astrocytes
- Principal Investigator
  
  TANAKA Koh-ichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hyogo University of Health Sciences
内分泌撹乱物質は注意欠陥多動性障害の原因となるか?Principal Investigator
- Principal Investigator
  
  西山信好
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
生体内物質によるシナプス可塑性および記憶・学習行動の調節機構
- Principal Investigator
  
  松木則夫
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
RESEARCH ON THE MECHANISM OF DETERIORATION OF BRAIN ISCHEMIC DISORDERS BY INTERLEUKIN-1Principal Investigator
- Principal Investigator
  
  NISHIYAMA Nobuyoshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  GRADUATE SCHOOL OF PHARMACEUTICAL SCIENCES, THE UNIVERSITY OF TOKYO
Protective effects of ATP and purinergic agents against brain neuronal cell deathPrincipal Investigator
- Principal Investigator
  
  NISHIYAMA Nobuyoshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
学習行動と長期増強現象の相関の解析
- Principal Investigator
  
  SAITO Hiroshi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
胸腺摘出により誘発される学習障害の特性解析Principal Investigator
- Principal Investigator
  
  西山信好
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neuroscience in general
- Research Institution
  The University of Tokyo
Pharmacological Analysis of Neurite Re-elongation
- Principal Investigator
  
  SAITO Hiroshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2011 2010 2009 2008

All Journal Article Presentation Book

[Book] Advances in Health and Disease. Volume 552022
- Author(s)
  Kitanaka J., Kitanaka N., Hall F.S., Kountz L.E., Hashimoto T., Hirabayashi K., Horie U., Iwasaki K., Kawasaki Y., Kimura M., Sakamoto T., Yashiro J., Tomita K., Igarashi K., Tanaka K., Uhl G.R., Sato T., Nishiyama N.
- Total Pages
  20
- Publisher
  Nova Science Publishers, Inc. (New York)
- ISBN
  9781685079987
- Data Source
  KAKENHI-PROJECT-21K06591
[Journal Article] Are Histamine H3 Antagonists the Definitive Treatment for Acute MethamphetamineIntoxication?2022
- Author(s)
  Kitanaka Nobue、Kitanaka, Junichi、Hall F. Scott、Tanaka, Koh-ichi、Tomita Kazuo、Igarashi Kento、Nishiyama Nobuyoshi、Sato Tomoaki、Uhl George R.
- Journal Title
  
  Current Drug Research Reviews
  
  Volume: 14 Issue: 3 Pages: 162-170
- DOI
  10.2174/2589977514666220414122847
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06591
[Journal Article] Metoprine, a histamine N-methyltransferase inhibitor, attenuates methamphetamine-induced hyperlocomotion via activation of histaminergic neurotransmission in mice2021
- Author(s)
  Kitanaka Nobue、Hall F. Scott、Kobori Shotaro、Kushihara Sota、Oyama Hiroyuki、Sasaoka Yasuki、Takechi Megumi、Tanaka Koh-ichi、Tomita Kazuo、Igarashi Kento、Nishiyama Nobuyoshi、Sato Tomoaki、Uhl George R.、Kitanaka Junichi
- Journal Title
  
  Pharmacology Biochemistry and Behavior
  
  Volume: 209 Pages: 173257-173257
- DOI
  10.1016/j.pbb.2021.173257
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06591
[Journal Article] Thymidine incorporation via nucleoside transporters on oxidative stress DNA injury.2011
- Author(s)
  Koh-ichi Tanaka、Nobue Kitanaka、Junichi Kitanaka、Tomoaki Sato、Takashige Nishikawa、Motoshiko Takemura、Nobuyoshi Nishiyama
- Journal Title
  
  Journal of Pharmacological Science 115 Suppliment 1.
  
  Pages: 134-134
- Data Source
  KAKENHI-PROJECT-20590098
[Journal Article] Thymidine incorporation via nucleoside transporters on oxidative stress injury.2010
- Author(s)
  Koh-ichi Tanaka、Nobue Kitanaka、Junichi Kitanaka、Tomoaki Sato、Takashige Nishikawa、Motoshiko Takemura、Nobuyoshi Nishiyama
- Journal Title
  
  Journal of Pharmacological Science 112 Suppliment 1.
  
  Pages: 190-190
- Data Source
  KAKENHI-PROJECT-20590098
[Journal Article] Role of astrocytic nucleoside transporters on oxidative stress.2010
- Author(s)
  Koh-ichi Tanaka、Nobue Kitanaka、Junichi Kitanaka、Tomoaki Sato、Takashige Nishikawa、Motoshiko Takemura、Nobuyoshi Nishiyama
- Journal Title
  
  Bulletin of the Japanese Society for Neurochemistry 49(No.2,3)
  
  Pages: 532-532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590098
[Journal Article] Regulation by p38 MAPK on hydrogen peroxide-induced thymidine incorporation in cultured astrocytes.2009
- Author(s)
  Koh-ichi Tanaka、Tomoaki Sato、Takashige Nishikawa、Junichi Kitanaka、Nobue Kitanaka、Motoshiko Takemura、Nobuyoshi Nishiyama
- Journal Title
  
  Journal of Pharmacological Science 109 Suppliment 1.
  
  Pages: 227-227
- Data Source
  KAKENHI-PROJECT-20590098
[Journal Article] Involvement of equilibrative and concentrative nucleoside transporters in hydrogen peroxide-induced thymidine incorporation in cultured astrocytes.2009
- Author(s)
  Koh-ichi Tanaka、Nobue Kitanaka、Junichi Kitanaka、Tomoaki Sato、Takashige Nishikawa、Motoshiko Takemura、Nobuyoshi Nishiyama
- Journal Title
  
  Neuroscience Research 65 Suppliment 1.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590098
[Journal Article] Effects of Ca^<2+>-ATPase inhibitors on hydrogen peroxide-induced thymidine incorporation into cultured astrocytes.2008
- Author(s)
  Koh-ichi Tanaka、Tomoaki Sato、Takashige Nishikawa、Junichi Kitanaka、Nobue Kitanaka、Motoshiko Takemura、Nobuyoshi Nishiyama
- Journal Title
  
  神経化学Bullketin of the Japanese Society for Neurochemistry 47
  
  Pages: 224-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590098
[Journal Article] Influence of hydrogen peroxide-induced thymidine incorporation on delayed cell death in cultured astrocytes.2008
- Author(s)
  Koh-ichi Tanaka、Tomoaki Sato、Takashige Nishikawa、Junichi Kitanaka、Nobue Kitanaka、Motoshiko Takemura、Nobuyoshi Nishiyama
- Journal Title
  
  Neuroscience Research 61 Suppliment 1.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590098
[Presentation] GSK-３阻害薬CHIR-99021前処置はモルヒネによるStraubの挙尾反応と退薬症状を抑制する2023
- Author(s)
  仲井聖典、北中順惠、濱名貴大、松田健太郎、湯瀬祥、藤井舞、津嶋祐一郎、富田和男、五十嵐健人、佐藤友昭、西山信好、北中純一
- Organizer
  第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06591
[Presentation] 放射線抵抗性がん細胞が抵抗性を失うと低下したFe2+量が親株レベルに戻る2023
- Author(s)
  富田和男, 桑原義和, Mehryar Habibi Roudkenar, 五十嵐健人, 田中康一, 北中純一, 北中順惠, 栗政明弘, 西山信好, 佐藤友昭
- Organizer
  第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06591
[Presentation] 幻覚剤2,5-dimethoxy-4-iodoamphetamineによって引き起こされる行動異常の特徴について2023
- Author(s)
  湯瀬祥、北中順惠、濱名貴大、松田健太郎、仲井聖典、富田和男、五十嵐健人、佐藤友昭、西山信好、北中純一
- Organizer
  第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06591
[Presentation] 隔離飼育されたddYマウスの攻撃的な咬合行動に対するジアゼパムの影響は雄と雌で異なる2023
- Author(s)
  五十嵐健人、口岩聡、口岩俊子、富田和男、田中康一、北中純一、北中順惠、西山信好、佐藤友昭
- Organizer
  第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06591
[Presentation] 幻覚剤2,5-dimethoxy-4-iodoamphetamineは短期空間記憶や気分の障害を引き起こす2023
- Author(s)
  北中純一、北中順惠、湯瀬祥、濱名貴大、松田健太郎、仲井聖典、富田和男、五十嵐健人、佐藤友昭、西山信好
- Organizer
  第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06591
[Presentation] GSK-3阻害薬CHIR-99021前処置は覚せい剤誘導常同行動を部分的に抑制する2022
- Author(s)
  194. 北中純一、北中順惠、富田和男、五十嵐健人、田中康一、佐藤友昭、西山信好
- Organizer
  第96回日本薬理学会年会／JPW2022
- Data Source
  KAKENHI-PROJECT-21K06591
[Presentation] GSK3阻害薬SB216763はモルヒネ作用のうちStraubの挙尾反応を選択的に抑制する2022
- Author(s)
  北中純一、北中順惠、五十嵐健人、富田和男、田中康一、佐藤友昭、西山信好
- Organizer
  第45回日本神経科学大会・第65回日本神経化学会大会・第32回日本神経回路学会大会合同大会
- Data Source
  KAKENHI-PROJECT-21K06591
[Presentation] GSK-3阻害薬前処置による覚せい剤誘導過運動・常同行動・報酬効果への効果.2022
- Author(s)
  北中順惠、北中純一、富田和男、五十嵐健人、田中康一、橋本拓磨、平林夏依、堀江詩卯、岩崎健太、河崎祐実、木村　陽、坂本昴士、矢代順哉、西山信好、佐藤友昭
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06591
[Presentation] GSK-3阻害薬は中枢作用を介してモルヒネ誘導Straubの挙尾反応を抑制する.2022
- Author(s)
  北中純一、北中順惠、富田和男、五十嵐健人、田中康一、橋本拓磨、平林夏依、堀江詩卯、岩崎健太、河崎祐実、木村　陽、坂本昴士、矢代順哉、西山信好、佐藤友昭
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06591
[Presentation] 覚せい剤併用におけるHMT阻害薬メトプリンの薬理学的特性について.2021
- Author(s)
  北中純一、北中順惠、小堀将太郎、櫛原聰太、大山裕之、笹岡保希、武地愛、田中康一、富田和男、五十嵐健人、西山信好、佐藤友昭
- Organizer
  第44回日本神経科学大会・第1回CJK国際会議・合同大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06591

1. SAITO Hiroshi (00012625)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. TANAKA Koh-ichi (30274848)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
3. 松木則夫 (70126168)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SATO Tomoaki (10284887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. Kitanaka Junichi (10278830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
6. 香月博志 (40240733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 池谷裕二 (10302613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 北中順惠 (30340954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
9. 木村信也 (70273703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Nishiyama Nobuyoshi 西山 信好

西山 信好 ニシヤマ ノブヨシ

NISHIYAMA Nobuyoshi 西山 信好

Research Projects

Research Products

Co-Researchers

Modulation of histaminergic neurotransmission and pharmacotherapy for drug abuse and dependence

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The change of DNA repair enzymes and nucleoside transoprters by oxydative stress in astrocytes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

内分泌撹乱物質は注意欠陥多動性障害の原因となるか?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生体内物質によるシナプス可塑性および記憶・学習行動の調節機構

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RESEARCH ON THE MECHANISM OF DETERIORATION OF BRAIN ISCHEMIC DISORDERS BY INTERLEUKIN-1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Protective effects of ATP and purinergic agents against brain neuronal cell deathPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

学習行動と長期増強現象の相関の解析

Principal Investigator

Project Period (FY)

Research Category

Research Institution

胸腺摘出により誘発される学習障害の特性解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pharmacological Analysis of Neurite Re-elongation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Advances in Health and Disease. Volume 552022

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Are Histamine H3 Antagonists the Definitive Treatment for Acute MethamphetamineIntoxication?2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metoprine, a histamine N-methyltransferase inhibitor, attenuates methamphetamine-induced hyperlocomotion via activation of histaminergic neurotransmission in mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Thymidine incorporation via nucleoside transporters on oxidative stress DNA injury.2011

Author(s)

Journal Title

Data Source

[Journal Article] Thymidine incorporation via nucleoside transporters on oxidative stress injury.2010

Nishiyama Nobuyoshi 西山信好

西山信好ニシヤマノブヨシ

NISHIYAMA Nobuyoshi 西山信好