IMAI Shin-ichi 今井伸一

Researcher Number	20213209
Other IDs
Affiliation (based on the past Project Information) *help	2008 – 2014: Sapporo Medical University, 医学部, 講師 2007: Sapporo Medical University, Department of Biochemistry School of Medicine, Assistant Professor 2007: Sapporo Medical University, Department of Biochemistry, School of Medicine, Assistant Professor 2004 – 2006: 札幌医科大学, 医学部, 助手 1990 – 1999: 札幌医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Functional biochemistry / Biological pharmacy / Anesthesiology/Resuscitation studies Except Principal Investigator General medical chemistry / Pathological medical chemistry / Functional biochemistry
Keywords	Principal Investigator ジアシルグリセロールキナーゼ / ジアシルグリセロール / ホスファチジン酸 / 酸化ストレス / 上皮増殖因子 / RACK1 / oxidative stress / tyrosine phosphorylation / PH domain / isozyme … More / phosphatidic acid / diacylglyicerol / diacylglyicerol kinase / チロシンリン酸化 / PHドメイン / アイソザイム / 神経傷害性疼痛 / 神経障害性疼痛 / メタロチオネイン / CRPS / 複合性局所疼痛症候群 / 腫瘍壊死因子α / 低分子量GTP結合タンパク質 / リン酸化 / 酵素 / 脂質 / シグナル伝達 / two-hybrid / 分化 / リン脂質合成 / 脱リン酸化 / ホスファターゼ … More Except Principal Investigator ホスファチジン酸ホスファターゼ / ジアシルグリセロールキナーゼ / ホスファチジン酸 / Diacylglycerol kinase / 亜鉛フィンガー / シグナル伝達 / Rac1 / NF-κB / signal transduction / リン脂質 / Signal transduction / cDNA cloning / Tーリンパ球 / 亜鉛フィンガ- / Insulin receptor / β2-Chimaerin / Apoptosis / Protein kinase C / Epidermal growth factor receptor / Racl / インスリン受容体 / β2-カイメリン / アポトーシス / プロテインキナーゼC / 上皮増殖因子受容体 / raft / phospholipid / phosphatidic acid phosphatase / diacylglycerol kinase / 遺伝子ターゲッティング / Phospholipids / Phosphatidic acid phosphatase / EF-ハンド / プレクストリン相同部位 / 細胞分化 / cDNAクローニング / 分子生物学 / Phosphatidic acid / T-lymphocyte / E-F hand / Zink-finger / DG kinase isozyme / Diacylglycerol(DG) kinase / EーFハンド / DGキナ-ゼアイソザイム / ジアシルグリセロ-ル(DG)キナ-ゼ / T-リンパ球 / E-Fハンド / DGキナーゼアイソザイム / 刺激情報伝達系 / ジアシルグリセロール(DG)キナーゼ / Calcium-binding protein / zinc finger / EF-hand motif / リンパ球 / リン脂質合成 / ジアシルグリセロ-ル / 情報伝達 / カルシウム結合タンパク質 / EFーハンド / ジアシルグリセロ-ルキナ-ゼ / EFハンド / 遺伝子工学 / ジアシルグソセロールキナーゼ Less

Study on the relationship between metallothionein-deficiency and pain in CRPSPrincipal Investigator
- Principal Investigator
  
  IMAI Shin-ichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Sapporo Medical University
The study of roles of RACK1 in physiological functions of diacylglycerol kinase(type II)Principal Investigator
- Principal Investigator
  
  IMAI Shin-ichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Sapporo Medical University
The study of functions of diacylglycerol kinase δ in signal transduction of epidermal growth factor receptorPrincipal Investigator
- Principal Investigator
  
  IMAI Shin-ichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Sapporo Medical University
Discovery and analysis of dovel lipid signal transduction complexes
- Principal Investigator
  
  SAKANE Fumio
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Sapporo Medical University
Investigation of the regulation mechanism of tumor necrosis factor α converting enzyme by type II diacylglycerol kinasesPrincipal Investigator
- Principal Investigator
  
  IMAI Shin-ichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Sapporo Medical University
Studies on regulatory mechanisms of phospholipid-metabolizing enzymes
- Principal Investigator
  
  KANOH Hideo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Sapporo Medical University
ジアシルグリセロールキナーゼと相互作用する細胞内因子の検索Principal Investigator
- Principal Investigator
  
  今井伸一
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Sapporo Medical University
ヒトジアシルグリセロールキナーゼα及びγ遺伝子の転写調節機構の検討Principal Investigator
- Principal Investigator
  
  今井伸一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Sapporo Medical University
Molecular analysis of enzymes involved in animal phospholipid biosynthesis
- Principal Investigator
  
  KANOH Hideo
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Sapporo Medical University School of Medicine
ホスファチジン酸ホスファターゼの活性調節機構の検討Principal Investigator
- Principal Investigator
  
  今井伸一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Sapporo Medical University
脂質性2次メッセンジャー代謝酵素に関する生化学的,遺伝子工学的検討
- Principal Investigator
  
  加納英雄
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
ジグリセリドキナーゼに関する生化学的,遺伝子工学的検討
- Principal Investigator
  
  KANOH Hideo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Sapporo Medical University
Role of Diacylglycerol Kinase lsozymes on the Expression of Cell Function.
- Principal Investigator
  
  YAMADA Keiko
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Sapporo Medical College
The function of DG kinase, a lipid phosphorylating enzyme having both EF-hands and zinc fingers.
- Principal Investigator
  
  KANOH Hideo
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Sapporo Medical College

All 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Patent

[Journal Article] 4)Significant increase of plasma tetranectin in ovx mice as defined by proteomics analysis.2014
- Author(s)
  Sasaki K, Ozasa Y, Iba K, Wada T, Imai S, Matsumoto K, Sohma H, Aoshima M, Yamashita T, Kokai Y
- Journal Title
  
  J Orthop Sci
  
  Volume: 19 Issue: 5 Pages: 809-819
- DOI
  10.1007/s00776-014-0586-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591686, KAKENHI-PROJECT-24592351
[Journal Article] Evaluation of annexin A5 as a biomarker for Alzheimer's disease and Dementia with Lewy bodies.2013
- Author(s)
  Sohma H, Imai S, Takei N, Honda H, Matsumoto K, Utsumi K, Matsuki K, Hashimoto E, Saito T, Kokai Y.
- Journal Title
  
  Front Aging Neurosci.
  
  Volume: 5 Pages: 1-7
- DOI
  10.3389/fnagi.2013.00015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659363, KAKENHI-PROJECT-24591686, KAKENHI-PROJECT-24592351
[Journal Article] Metallothionein deficiency in the injured peripheral nerves of complex regional pain syndrome as revealed by proteomics2012
- Author(s)
  Oki G, Wada T, Iba K, Aiki H, Sasaki K, Imai S, Sohma H, Matsumoto K, Yamaguchi M, Fujimiya M, Yamashita T and Kokai Y
- Journal Title
  
  Pain
  
  Volume: 153 Pages: 532-539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570145
[Journal Article] Early expression of plasma CCL8 closely correlates with survival rate of acute graft-vs.-host disease in mice2011
- Author(s)
  Yamamoto M, Ota A, Hori T, Imai S, Sohma H, Suzuki N, Hatakeyama N, Inazawa N, Ito YM, Kimura H, Tsutsumi H and Kokai Y
- Journal Title
  
  Exp. Hematol
  
  Volume: 39 Pages: 1101-1112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570145
[Journal Article] Metallothionein deficiency in the injured peripheral nerves of complex regional pain syndrome as revealed by proteomics2011
- Author(s)
  Oki G
- Journal Title
  
  Pain
  
  Volume: 153 Issue: 3 Pages: 532-539
- DOI
  10.1016/j.pain.2011.11.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591489, KAKENHI-PROJECT-24592351
[Journal Article] Investigation of annexin A5 as a biomarker for Alzheimer's disease using neuronal cell culture and mouse model2010
- Author(s)
  Yamaguchi M, Kokai Y, Imai S, Utsumi K, Matsumoto K, Honda H, Mizue Y, Momma M, Maeda T, Toyomasu S, Ito YM, Kobayashi S, Hashimoto E, Saito T and Sohma H
- Journal Title
  
  J. Neurosci. Res.
  
  Volume: 88 Pages: 2682-2692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570145
[Journal Article] Diacylglycerol kinase α enhances protein kinase Cζ-dependent phosphorylation at Ser311 of p65/RelA subunit of nuclear factor-κB2009
- Author(s)
  Kai M, Yasuda S, Imai S, Toyota M, Kanoh H and Sakane F
- Journal Title
  
  FEBS Lett.
  
  Volume: 583 Pages: 3265-3268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570145
[Journal Article] Diacylglycerol kinaseδassociates with receptor for activated C kinase I, RACKl.2009
- Author(s)
  Imai, S.
- Journal Title
  
  Biochim. Biophys. Acta 1791
  
  Pages: 246-253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570136
[Journal Article] Diacylglycerol kinaseηaugments C-Raf activity and B-Raf/C-Raf heterodimerization2009
- Author(s)
  Yasuda S, Kai M, Imai S, Takeishi K, Taketomi A, Toyota M, Kanoh H and Sakane F
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 284 Pages: 29559-29570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570145
[Journal Article] Diacylglycerol kinase δ associates with receptor for activated C kinase 1, RACK12009
- Author(s)
  Imai S, Yasuda S, Kai M, Kanoh H, Sakane F
- Journal Title
  
  Biochim. Biophys. Acta 1791
  
  Pages: 246-253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570136
[Journal Article] Regulation of enzyme localization by polymerization : Polymer formation by the SAM domain of diacylglycerol kinase 812008
- Author(s)
  Harada, B., T., Knight, M., J., Imai, S., Qiao, F., Ramachander, R., Sawaya, M. R., Gingery, M., Sakane, F.,d Bowie, J. U
- Journal Title
  
  Structure 16(3)
  
  Pages: 380-387
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570132
[Journal Article] Phorbol ester and hydrogen peroxide synergistically induce the interaction of diacylglycerol kinase γ with the Src homology 2 and C1 domains of β2-chimaerin2008
- Author(s)
  Yasuda S, Kai M, Imai S, Kanoh H, Sakane F
- Journal Title
  
  Biochem. J 409
  
  Pages: 95-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570136
[Journal Article] Phorbol ester and hydrogen peroxide synergistically induce the interaction of diacylglycerol kinase y with the Src homology 2 and Cl domains of β2-chimaerin2008
- Author(s)
  Yasuda, S., Kai, M., Imai, S., Kanoh, H., Sakane, F
- Journal Title
  
  Biochem. J 409 (1)
  
  Pages: 95-106
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570132
[Journal Article] Regulation of enzyme localization by polymerization : polymer formation by the SAM domain of diacylglycerol kinase δ12008
- Author(s)
  Harada BT, Knight MJ, Imai S, Qiao F, Ramachander R, Sawaya MR, Gingery M, Sakane F, Bowie JU
- Journal Title
  
  Structure 16
  
  Pages: 380-387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570136
[Journal Article] Rab7 regulates maturation of the melanosomal matrix protein gp100/Pmel17/Sil2008
- Author(s)
  Kawakami, A., Sakane, F., Imai, S., Yasuda, S., Kai, M., Kanoh, H., Jin, H-Y., Hirosaki, K., Yamashita, T., Fisher, D. E., Jimbow, K
- Journal Title
  
  J. Invest. Dermatol 128 (1)
  
  Pages: 143-150
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570132
[Journal Article] Rab7 regulates maturation of the melanosomal matrix protein gp100/Pmel17/Silv2008
- Author(s)
  Kawakami A, Sakane F, Imai S, Yasuda S, Kai M, Kanoh H, Jin H-Y, Hirosaki K, Yamashita T, Fisher D. E, Jimbow K
- Journal Title
  
  J. Invest. Dermatol 128
  
  Pages: 143-150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570136
[Journal Article] Diacylglycerol kinases as emerging potential drug targets for a variety of diseases2008
- Author(s)
  Sakane F, Imai S, Kai M, Yasuda S, Kanoh H
- Journal Title
  
  Curr. Drug Targets 9
  
  Pages: 626-640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570136
[Journal Article] Tyrosine phosphorylation of β2-chimaerin by Src-family kinase negatively regulates its Rac-specific GAP activity. Biochim2007
- Author(s)
  Kai M, Yasuda S, Imai S, Kanoh H, Sakane F
- Journal Title
  
  Biophys. Acta 1773
  
  Pages: 1407-1415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570136
[Journal Article] 「研究成果報告書概要(欧文)」より2007
- Author(s)
  Yanagisawa, K., Yasuda, S., Kai, M., Imai, S., Yamada, K., Yamashita, T., Jimbow, K., Kanoh, H., Sakane, F
- Journal Title
  
  Biochim. Biophys. Acta - Mol. Cell Biol. Lipids 1771 (4)
  
  Pages: 462-474
- Data Source
  KAKENHI-PROJECT-18570132
[Journal Article] Diacylglycerol kinase γ interacts with and activates β2-chimaerin, a Rae-specific GAP, in response to epidermal growth factor2007
- Author(s)
  Yasuda, S., Kai, M., Imai, S., Kanoh, H., Sakane, F
- Journal Title
  
  FEBS Lett 581(3)
  
  Pages: 551-557
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570132
[Journal Article] Diacylglycerol kinase γ interacts with and activates β2-chimaerin, a Rac-specific GAP, in response to epidermal growth facto2007
- Author(s)
  Yasuda S, Kai M, Imai S, Kanoh H, Sakane F
- Journal Title
  
  FEBS Lett 581
  
  Pages: 551-557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570136
[Journal Article] Diacylglycerol kinases : Why so many of them?2007
- Author(s)
  Sakane, F., Imai, S., Kai, M., Yasuda, S., Kanoh, H
- Journal Title
  
  Biochim. Biophys. Acta - Mol. Cell Biol. Lipids 1771(7)
  
  Pages: 793-806
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570132
[Journal Article] Diacylglycerol kinases : why so many of them?2007
- Author(s)
  Sakane F, Imai S, Kai M, Yasuda S, Kanoh H
- Journal Title
  
  Biochim. Biophys. Acta 1771
  
  Pages: 793-806
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570136
[Journal Article] Diacylglycerol kinase α suppresses tumor necrosis factor-α-induced apoptosis of human melanoma cells through NF-κB activation2007
- Author(s)
  Yanagisawa K, Yasuda S, Kai M, Imai S, Yamada K, Yamashita T, Jimbow K, Kanoh H, Sakane F
- Journal Title
  
  Biochim. Biophys. Acta 1771
  
  Pages: 462-474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570136
[Journal Article] yrosine phbsphorylation of β2-chimaerin by Src-family kinase negatively regulates its Rae-specific GAP activity2007
- Author(s)
  Kai, M., Yasuda, S., Imai, S., Kanoh, H., Sakane, F
- Journal Title
  
  Biochim. Biophys. Acta - Mol. Cell Res 1773 (9)
  
  Pages: 1407-1415
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570132
[Journal Article] Lipid phosphate phosphatases 1 and 3 are localized in different lipid rafts2006
- Author(s)
  Kai, M., Sakane, F., Jia, Y-J., Imai, S., Yasuda, S., Kanoh, H
- Journal Title
  
  J. Biochem 140 (5)
  
  Pages: 677-686
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570132
[Journal Article] Identification and characterization of a novel human type II diacylglycerol kinase, DGKκ2005
- Author(s)
  Shin-ichi Imai
- Journal Title
  
  J.Biol.Chem. 280・48
  
  Pages: 39870-39881
- Data Source
  KAKENHI-PROJECT-16570119
[Journal Article] Identification and characterization of a novel human type II diacylglycerol kinase, DGKκ2005
- Author(s)
  Shin-ichi Imai
- Journal Title
  
  J.Biol.Chem. 280(48)
  
  Pages: 39870-39881
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570119
[Journal Article] Identification and characterization of a novel human type II diacylglycerol kinase, DGKκ2005
- Author(s)
  Shin-ichi Imai
- Journal Title
  
  J. Biol. Chem. 280・48
  
  Pages: 39870-39881
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570119
[Journal Article] The plasma membrane translocation of diacylglycerol kinase delta1 is negatively regulated by conventional protin kinase C-dependent phosphorylation at Ser-22 and Ser-26 within the pleckstrin homology domain2004
- Author(s)
  Shin-ichi Imai
- Journal Title
  
  Biochem.J. 382・3
  
  Pages: 957-966
- Data Source
  KAKENHI-PROJECT-16570119
[Journal Article] The plasma membrane translocation of diacylglycerol kinase δ1 is negatively regulated by conventional protein kinase C-dependent phosphorylation at Ser-22 and Ser-26 within the pleckstrin homology domain2004
- Author(s)
  Shin-ichi Imai
- Journal Title
  
  Biochem.J. 382(Pt.3)
  
  Pages: 957-966
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570119
[Journal Article] The plasma membrane translocation of diacylglycerol kinase δ1 is negatively regulated by conventional protein kinase C-dependent phosphorylation at Ser-26 within the pleckstrin homology domain2004
- Author(s)
  Shin-ichi Imai
- Journal Title
  
  Biochem. J. 382・Pt3
  
  Pages: 957-966
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570119
[Journal Article] Diacylglycerol kinases as emerging potential drug targets for a variety of diseases. Special issue "Peripheral proteins as drug targets"
- Author(s)
  Sakane, F., Imai, S., Kai, M., Yasuda, S., Kanoh, H
- Journal Title
  
  Curr. Drug Targets (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570132
[Patent] 疼痛を治療、改善、または予防するための組成物2011
- Inventor(s)
  小海康夫、大木豪介、松本圭代、今井伸一、和田卓郎
- Industrial Property Rights Holder
  札幌医科大学
- Industrial Property Number
  2011-036855
- Filing Date
  2011-02-23
- Data Source
  KAKENHI-PROJECT-21570145
[Patent] 疼痛を治療、改善、または予防するための組成物2011
- Inventor(s)
  今井伸一
- Industrial Property Rights Holder
  札幌医科大学
- Industrial Property Number
  2011-036855
- Filing Date
  2011-02-23
- Data Source
  KAKENHI-PROJECT-21570145
[Patent] アミロイドβ神経障害バイオマーカー2010
- Inventor(s)
  小海康夫、相馬仁、今井伸一、松本圭代、木村成寿
- Industrial Property Rights Holder
  札幌医科大学
- Industrial Property Number
  2010-280331
- Filing Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-21570145
[Patent] アミロイドβ神経障害バイオマーカー2010
- Inventor(s)
  今井伸一
- Industrial Property Rights Holder
  札幌医科大学
- Industrial Property Number
  2010-280331
- Filing Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-21570145
[Presentation] 坐骨神経部分結紮モデルにおけるメタロチオネイン発現の経時的変化とメタロチオネイン投与による神経障害性疼痛の抑制効果2014
- Author(s)
  藤田安詞、和田卓郎、射場浩介、大木豪介、山下敏彦、今井伸一、小海康夫
- Organizer
  第126回北海道整形災害外科学会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-24592351
[Presentation] Neuropathic pain can be suppressed by the recombinant metallothionein.2013
- Author(s)
  Fujita Y, Wada T, Iba K, Oki G, Imai S, Kokai Y, Yamashita T.
- Organizer
  4th International Congress on Neuropathic Pain
- Place of Presentation
  Toronto, CANADA
- Data Source
  KAKENHI-PROJECT-24592351
[Presentation] メタロチオネイン投与による神経障害性疼痛の抑制効果2013
- Author(s)
  藤田安詞、和田卓郎、射場浩介、大木豪介、山下敏彦、今井伸一、小海康夫
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-24592351
[Presentation] Metallothionein deficiency in the injured peripheral nerves of complex regional pain syndrome as revealed by proteomics.2013
- Author(s)
  Imai S, Oki G, Fujita Y, Sohma H, Takei N, Wada T, Yamashita T, Kokai Y.
- Organizer
  4th International Congress on Neuropathic Pain
- Place of Presentation
  Toronto, CANADA
- Data Source
  KAKENHI-PROJECT-24592351
[Presentation] Metallothionein deficiency in the injured peripheral nerves of complex regional pain syndrome as revealed by proteomics.2012
- Author(s)
  Oki G, Wada T, Iba K, Kanaya K, Yamashita T, Imai S, Kokai Y.
- Organizer
  67th Annual Meeting of The American Society for Surgery of the Hand
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-24592351
[Presentation] プロテオミクス解析によるCRPS関連タンパク質の探索2011
- Author(s)
  今井伸一
- Organizer
  第44回北海道病理談話会
- Place of Presentation
  旭川
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-21570145
[Presentation] プロテオミクス解析によるCRPS関連タンパク質の探索2011
- Author(s)
  今井伸一
- Organizer
  第44回北海道病理談話会
- Place of Presentation
  旭川市国際会議場(北海道)
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-21570145
[Presentation] ジアシルグリセロールキナーゼδはRACKl(receptor foractivated C kinase l)と結合する2008
- Author(s)
  今井伸一
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19570136
[Presentation] ジアシルグリセロールキナーゼδはRACK1(receptor for activated Ckinase 1)と会合する2008
- Author(s)
  今井伸一
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19570136
[Presentation] ジアシルグリセロールキナーゼδはRACKl(receptor for activated C kinase l)と会合する2008
- Author(s)
  今井伸一
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19570136
[Presentation] ジアシルグリセロールキナーゼδはRACK1(receptor for activated Ckinase 1)と結合する2008
- Author(s)
  今井伸一
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19570136
[Presentation] ジアシルグリセロールキナーゼδとRACK1は互いの複数のドメインを介して結合している2007
- Author(s)
  今井伸一, ら
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570132
[Presentation] ジアシルグリセロールキナーゼδとRACK1は互いの複数のドメインを介して結合している2007
- Author(s)
  今井伸一
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19570136
[Presentation] ジアシルグリセロールキナーゼδとRACKIは互いの複数のドメインを介して結合している2007
- Author(s)
  今井伸一, ら
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18570132
[Presentation] Rab7 interacts with the melanosomal matrix protein gp100/Pme117/Silv and regulates its maturation in MMAc human melanoma cells2006
- Author(s)
  Kawakami, A., Sakane, F., Imai, S., Kanoh, H., Oukura, M., Hirosaki, K., Yamashita, T., Jimbow, K
- Organizer
  13th Meeting of the European Society for Pigment Cell Research. Barcelona
- Place of Presentation
  Spain
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570132
[Presentation] Rab7 interacts with the melanosomal matrix protein gp100/Pme117/Silv and regulates its maturation in MMAc human melanoma cells2006
- Author(s)
  Kawakami, A., Sakane, F., Imai, S., Kanoh, H., Oukura, M., Yamashita, T., Jimbow, K
- Organizer
  7th Annual Meeting of the Society for InvestigativeK.Dermetology. Philladelphia, Pennsylvania
- Place of Presentation
  USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570132
[Presentation] Diacylglycerol kinase δ binds to RACK1,receptor for activated C kinase 12006
- Author(s)
  Imai, S., et. al.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570132
[Presentation] Src-family kinase and phorbol ester/diacylglycerol signals cooperate to phosphorylate and activate β2-chimaerin, a Rac-specific GAP2006
- Author(s)
  Kai, M., Yasuda, S., Imai, S., Sakane, F., Kanoh, H
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and Ilth FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570132
[Presentation] Diacylglycerol kinase 8 binds to RACK1, receptor for activated C kinase 12006
- Author(s)
  Imai, S., Yasuda, S., Kai, M., Sakane, F., Kanoh, H
- Organizer
  20th IUBMB International Congress of Biochemist ry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570132
[Presentation] Regulation of β2-chimaerin by diacylglycerol kinasey2006
- Author(s)
  Yasuda, S., Kai, M., Imai, S., Sakane, F., Kanoh, H
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570132
[Presentation] リコンビナントメタロチオネインによる神経障害性疼痛の抑制
- Author(s)
  藤田安詞、和田卓郎、射場浩介、大木豪介、山下敏彦、今井伸一、小海康夫
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24592351
[Presentation] CRPSにおけるメタロチオネイン欠損と疼痛の関連
- Author(s)
  今井伸一、藤田安詞、大木豪介、松木圭代、武井則雄、相馬仁、和田卓郎、山下敏彦、小海康夫
- Organizer
  第45回北海道病理談話会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24592351

1. KANOH Hideo (70045475)

# of Collaborated Projects: 7 results

# of Collaborated Products: 13 results
2. SAKANE Fumio (10183815)

# of Collaborated Projects: 7 results

# of Collaborated Products: 23 results
3. KAI Masahiro (80260777)

# of Collaborated Projects: 5 results

# of Collaborated Products: 11 results
4. WADA Ikuo (40182969)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. YAMADA Keiko (80045541)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 安田智 (20381262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. 相馬仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 今井博久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 小海康夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IMAI Shin-ichi 今井 伸一

Research Projects

Research Products

Co-Researchers

Study on the relationship between metallothionein-deficiency and pain in CRPSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of roles of RACK1 in physiological functions of diacylglycerol kinase(type II)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of functions of diacylglycerol kinase δ in signal transduction of epidermal growth factor receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Discovery and analysis of dovel lipid signal transduction complexes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of the regulation mechanism of tumor necrosis factor α converting enzyme by type II diacylglycerol kinasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on regulatory mechanisms of phospholipid-metabolizing enzymes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ジアシルグリセロールキナーゼと相互作用する細胞内因子の検索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒトジアシルグリセロールキナーゼα及びγ遺伝子の転写調節機構の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular analysis of enzymes involved in animal phospholipid biosynthesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ホスファチジン酸ホスファターゼの活性調節機構の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脂質性2次メッセンジャー代謝酵素に関する生化学的,遺伝子工学的検討

Principal Investigator

Project Period (FY)

Research Category

Research Institution

ジグリセリドキナーゼに関する生化学的,遺伝子工学的検討

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of Diacylglycerol Kinase lsozymes on the Expression of Cell Function.

Principal Investigator

Project Period (FY)

Research Category

Research Field

IMAI Shin-ichi 今井伸一