WADA Morimasa 和田守正

… Alternative Names

和田守正ワダモリマサ

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Researcher Number	20220965
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2007 – 2012: Nagasaki International University, 薬学部, 教授 2011: 長崎国際大学, 薬学部 2005: Kyushu University, Department of Medical Biochemistry, Associate Proffesor, 大学院医学研究院, 助教授 2004: 九州大学, 医学研究院, 助教授 2000 – 2004: Dept.of Med.Biochemistry, Grad.Sch.of Med.Sciences KYUSHU UNIVERSITY Associate Professor, 大学院・医学研究院, 助教授 … More 1999: 九州大学, 大学院・医学系研究科, 助教授 1996 – 1998: Faculty of Medicine Kyushu University, Associate Professor, 医学部, 助教授 1993 – 1995: Kyushu University Faculty of Medicine, 医学部, 助手 1990: 京都薬科大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / General medical chemistry / Functional biochemistry / Pathological medical chemistry / 分子遺伝学・分子生理学 Except Principal Investigator Biological Sciences / Pathological medical chemistry / Urology
Keywords	Principal Investigator 薬剤耐性 / ABCファミリー / トランスポーター / YAC / 発がん / 生体防御 / ABCトランスポーター / MRP2 / MDR1 / 排出ポンプ … More / Dubin-Johnson症候群 / 発現クローニング / 酵母人工染色体 / MDR / ABCB1 / ABCC2 / 分子医薬学 / 膜輸送 / 輸送タンパク質 / 生体分子 / ABC膜タンパク質 / 副作用 / 薬効 / 遺伝子多型 / DNAメチル化 / 位置効果 / YAC導入 / cMOAT / ディファレンシャル・ディスプレイ / MRP / Colorectal cancer risk / Substrate affinity / Chimeric proteins / Effulux pump / ABC membrane protein / 原子構造 / ロイコトリエンC4 / 細胞内局在 / 機能制御 / ナノマシーン / 基質認識 / 遺伝性黄疸 / 膜ベシクル輸送解析 / 大量精製 / 基質親和性 / 大腸がんリスク / 気質親和性 / キメラタンパク質 / color blinedness / topoisomerasell / yeast artificial chromosome / repeat / Fragile X syndrome / genetic diseases / tumor / genomic instability / サッカロミセス / セントロメア / トポイソメラーゼII / リピート / 色盲 / がん / Fragile X症候群 / 遺伝性疾患 / ゲノム不安定性 / 分子相互作用 / タンパク質 / 薬物治療抵抗性 / 腸管腫瘍形成 / 分子間相互作用 / 蛋白質 / 薬物治療抵抗性薬物治療抵抗性 / 異物排出 / 発がん感受性 / 8オキソグアニン / P-gp / 基質スクリーニング / 発現レベル / テーラーメード治療 / 排出機構 / 解毒抱合 / 遺伝子ファミリー / エクソントラップ法 / シスプラチン / 抗がん剤感受性 / 卵巣腫瘍 / ビリルビン排泄障害 / 遺伝子発現 / メチル化 / 機能的導入 / チャネル / YBC / チャンネル / ZーDNA / ミニサテライトDNA / HPRT遺伝子 / 組み換え / 相同組み換え / Gene Targeting … More Except Principal Investigator MRP / YAC / MDR1 / 遺伝子多型 / YB-1 / 白血病 / MRP遺伝子 / 副作用 / ABCトランスポータ / オーダーメード医療 / 遺伝子 / ABCトランスポーター / MRP2 / 酵母人工染色体 / cMOAT / MOAT / 多剤耐性 / 遺伝子発現 / 遺伝子増幅 / 特異的 / 蛋白質 / 精子 / 精巣 / MRD遺伝子 / Dubin-Johnson症候群 / プロモーター / 多剤耐性遺伝子 / DNA methylation / Dubin-Johnson syndrome / efflux pump / anticancer agents / 遺伝性疾患 / 遺伝子発現調節 / 抗癌剤感受性 / 薬剤排出ポンプ / 抗がん剤 / DNAメチル化 / 異物排出 / ABCsuperfamily / amplification / chromosome 7 / P-glycoproteins / multidrug resistance / CpG領域 / エキソントラップ / PEGフュージョン法 / コンティングマップ / FISH / 多剤耐性関連蛋白 / 第7染色体長腕21 / Y-box結合蛋白 / GSX-pump / ヒト7番染色体 / MDR / Gene expression / Gene amplification / Genome analysis / Yeastartifitial chromosome / DNA topoisomerase / Multi drug resistance / YACベクタ- / ヒトゲノム解析 / 抗癌剤耐性 / 多剤耐性遺伝子ー1 / ヒト第7番染色体 / ゲノム解析 / DNAトポイソメラーゼ / 制癌剤耐性 / 治療 / 発生 / 男性不妊 / Germ cell / Spermatogenesis / Infertility / Testis / Sperm / 遺伝子破壞 / マウス / 幹細胞 / 分化・発生 / 生殖細胞 / MDR遺伝子 / 栄養 / ライフスタイル / 大腸線種 / 生活習慣要因 / 患者対照研究 / 食物 / 生活習慣 / 症例対照研究 / 食物栄養 / 大腸がん / Dubin Johnson 疾病群 / MRP3 / cMUAT / 肝炎ウイルス / グルタチオン / 大腸癌 / 抗がん剤感受性 / 腸肝循環 / C型肝炎 / 分化度 / ABC / 肝炎 / 遺伝病 / 細胞死 / 転写因子 / 制癌剤 / DNAトポイソメラーゼII Less

Exploitation of noninvasive genetic diagnosis for therapy of male infertility
- Principal Investigator
  
  TANAKA Hiromitsu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagasaki International University
受精・発生を支える精子細胞特異的に発現する遺伝子の欠失マウスの解析
- Principal Investigator
  
  TANAKA Hiromitsu
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagasaki International University
Host-defense by excretion and it's failure generating diseasesPrincipal Investigator
- Principal Investigator
  
  WADA Morimasa
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagasaki International University
Host-defense through excretion of xenobiotics and related diseasesPrincipal Investigator
- Principal Investigator
  
  WADA Morimasa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagasaki International University
解毒・排出系の遺伝子多型に基づく薬剤応答・副作用の予測
- Principal Investigator
  
  松崎彰信
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
解毒・排出系の遺伝子多型に基づく薬剤応答・副作用の予測
- Principal Investigator
  
  松崎彰信
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
生体防御のフロントライン:異物排出機能の破綻と病態Principal Investigator
- Principal Investigator
  
  和田守正
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyushu University
解毒・排出系の遺伝子多型に基づく薬剤応答・副作用の予測
- Principal Investigator
  
  松崎彰信
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
解毒・排出系の遺伝子多型に基づく薬剤応答、副作用の予測Principal Investigator
- Principal Investigator
  
  和田守正
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Molecular structure and functional regulation of ATP-binding cassette transportersPrincipal Investigator
- Principal Investigator
  
  WADA Morimasa
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
解毒・排出系の遺伝子多型に基づく薬剤応答、副作用の予測Principal Investigator
- Principal Investigator
  
  和田守正
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
生活習慣要因と大腸がんに関する患者対照研究
- Principal Investigator
  
  古野純典
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
ABC Transporters in Cancer and Other Diseases
- Principal Investigator
  
  KUWANO Michihiko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYUSHU UNIVERSITY
巨大ヒトゲノム導入による機能解析Principal Investigator
- Principal Investigator
  
  和田守正
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
ヒトcMOATの遺伝疾病と癌への関与
- Principal Investigator
  
  UCHIUMI Takeshi
- Project Period (FY)
  1998 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
新しいヒトABCファミリーcMOAT遺伝子は抗がん剤感受性を制御するか?Principal Investigator
- Principal Investigator
  
  和田守正
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
巨大ヒトゲノム導入による機能解析Principal Investigator
- Principal Investigator
  
  和田守正
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
新しいグルタチオン抱合体およびP糖蛋白型排出ポンプの構造と機能Principal Investigator
- Principal Investigator
  
  和田守正
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
巨大ヒトゲノム導入による機能解析Principal Investigator
- Principal Investigator
  
  和田守正
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Identification of genetic factors involved in the human genomic instabilityPrincipal Investigator
- Principal Investigator
  
  WADA Morimasa
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kyushu University
新しいグルタチオン抱合体およびP糖蛋白型排出ポンプの構造と機能Principal Investigator
- Principal Investigator
  
  和田守正
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
癌細胞における抗癌剤によるストレス応答を介した細胞死と耐性の分子機序
- Principal Investigator
  
  KOHNO Kimitoshi
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
The Analysis of Human MDR Gene Family Using YAC Clones.
- Principal Investigator
  
  KOHNO Kimitoshi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  University of Occupational and Environmental Health
  Kyushu University
Joint study on human genomic analysis of drug resistance
- Principal Investigator
  
  KUWANO Michihiko
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyushu University Faculty of Medicine
  大分医科大学
Gene Targetingによる遺伝子機能の解析Principal Investigator
- Principal Investigator
  
  和田守正
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  Kyoto Pharmaceutical University

All 2012 2011 2010 2009 2008 2007 2006 2004 2003 2002 2001 1996 Other

All Journal Article Presentation Book Patent

[Book] コンパスシリーズ「分子生物学-創薬・テーラーメード医療に向けて-」2010
- Author(s)
  和田守正
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21590323
[Book] コンパスシリーズ「分子生物学-創薬・テーラーメード医療に向けて-」2010
- Author(s)
  和田守正(共著)
- Total Pages
  238
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21590323
[Book] MEMBRANE TRANSPORT DISEASES-Molecular basis of inherited transport defects, (edited by S. Broer and C. A. Wagner) : (分担執筆)(Canalicular multispecific organic anion transporter, ABCC2)2003
- Author(s)
  Wada, M.
- Total Pages
  390
- Publisher
  NY Kluwer Academic/ Plenum Publishers
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Book] 生命工学、新しい生命へのアプローチ(シリーズ・バイオサイエンスの新世紀) : (分担執筆)酵母人工染色体2002
- Author(s)
  和田守正
- Total Pages
  298
- Publisher
  共立出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Book] 薬物動態、作用と遺伝子多型 : (分担執筆)MRP2/cMOATの生理機能と変異・遺伝子多型2001
- Author(s)
  和田守正
- Total Pages
  457
- Publisher
  医薬ジャーナル社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] Suppression of intestinal polyp development in ApcMin/+mice through inhibition of P-glycoprotein using verapamil2012
- Author(s)
  Kyoko Fujimoto, Gen Fujii, Michihiro Mutoh, Masa, Yasunaga, Hiromitsu Tanaka, Morimasa Wada
- Journal Title
  
  European Journal of Cancer Prevention
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590323
[Journal Article] Suppression of intestinal polyp development in ApcMin/+ mice through inhibition of P-glycoprotein using verapamil2012
- Author(s)
  Kyoko Fujimoto, Gen Fujii, Michihiro Mutoh, Masa Yasunaga, Hiromitsu Tanaka, Morimasa Wada
- Journal Title
  
  European Journal of Cancer Prevention
  
  Volume: (in press) Issue: 1 Pages: 8-10
- DOI
  10.1097/cej.0b013e328353ede8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590323
[Journal Article] A Single Nucleotide Polymorphism within the Novel Sex-Linked Testis-Specific Retrotransposed PGAM42012
- Author(s)
  Okuda H, Tsujimura A, Irie S, Yamamoto K, Fukuhara S, Matsuoka Y, Takao T, Miyagawa Y, Nonomura N, Wada M, Tanaka H.
- Journal Title
  
  Gene Influences Human Male Fertility. PLoS ONE
  
  Volume: 7:e35195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591810
[Journal Article] Primary screening of single nucleotide polymorphisms in human calreticulin 3(CALR3).2011
- Author(s)
  Irie S, Nakamura J, Miyagawa Y, Tsujimura A, Okuda H, Yamamoto K, Fukuhara S, Yoshioka I, Hiroshi K, Matsuoka Y, Takao T, Nonomura N, Ikawa M, Tokuhiro K, Okabe M, Shibata T, Fujimoto K, Wada M, Tanaka H
- Journal Title
  
  The Open Androl J
  
  Volume: 3 Pages: 30-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591810
[Journal Article] Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1.2010
- Author(s)
  Kato Y, Kubo Y, Iwata D, Kato S, Sudo T, Sugiura T, Kagaya T, Wakayama T, Hirayama A, Sugimoto M, Sugihara K, Kaneko S, Soga T, Asano M, Tomita M, Matsui T, Wada M, Tsuji A.
- Journal Title
  
  Pharm Res
  
  Volume: 27 Pages: 832-840
- NAID
  120002224385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590323
[Journal Article] Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN12010
- Author(s)
  Kato Y, Kubo Y, Iwata D, Kato S, Sudo T, Sugiura T, Kagaya T, Wakayama T, Hirayama A, Sugimoto M, Sugihara K, Kaneko S, Soga T, Asano M, Tomita M, Matsui T, Wada M, Tsuji A.
- Journal Title
  
  Pharm Res
  
  Volume: 27 Pages: 832-840
- NAID
  120002224385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590323
[Journal Article] Unique expression of encoding an acrosomal protein(ACPIN1) and salivary-specific protein(SAGSIN1) alternatively translated from two open reading frames on Acpin1 mRNA2009
- Author(s)
  Ueda T, Manabe H, Keizo T, Hirose M, Matsuoka Y, Miyagawa Y, Tsujimura A, Fujita K, Wada M, Okuyama A, Tanaka H.
- Journal Title
  
  Int. J. Urol
  
  Volume: 16 Pages: 639-646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590323
[Journal Article] Unique expression of encoding an acrosomal protein (ACPIN1) and salivary-specific protein (SAGSIN1) alternatively translated from two open reading frames on Acpinl mRNA.2009
- Author(s)
  Ueda T, Manabe H, Keizo T, Hirose M, Matsuoka Y, Miyagawa Y, Tsujimura A, Fujita K, Wada M, Okuyama A, Tanaka H.
- Journal Title
  
  Int.J.Urol. 16
  
  Pages: 639-646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590323
[Journal Article] OAZ-t/OAZ3 is essential for rigid connection of sperm tails to heads in mouse.2009
- Author(s)
  Tokuhiro K, Isotani A, Yokota S, Yano Y, Oshio S, Hirose M, Wada M, Fujita K, Ogawa Y, Okabe M, Nishimune Y, Tanaka H.
- Journal Title
  
  PLoS Genet. 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590323
[Journal Article] OAZ-t/OAZ3 is essential for rigid connection of sperm tails to heads in mouse2009
- Author(s)
  Tokuhiro K, Isotani A, Yokota S, Yano Y, Oshio S, Hirose M, Wada M, Fujita K, Ogawa Y, Okabe M, Nishimune Y, Tanaka H.
- Journal Title
  
  PLoS, Genet
  
  Volume: 5 Pages: 1000712-1000712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590323
[Journal Article] Molecular cloning and functional characterization of cynomolgus monkey multidrug resistance-associated protein 2 (MRP2).2008
- Author(s)
  Yasunaga, M., Takemura, M., Fujita, K., Yabuuchi, H., Wada, M.
- Journal Title
  
  Eur. J. Pharm. Sciences 35
  
  Pages: 326-334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590293
[Journal Article] Molecularcloning and functional characterization of cynomolgus monkey multidrug resistance-associated protein 2 (MRP2)2008
- Author(s)
  Yasunaga, M., Takemura, M., Fujita, K., Yabuuchi, H., and Wada, M
- Journal Title
  
  Eur. J. Pharm. Sciences 35
  
  Pages: 326-334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590293
[Journal Article] ATP加水分解共役型排出ポンプの構造、生理機能と疾病2007
- Author(s)
  和田守正、藤田京子
- Journal Title
  
  生化学 79
  
  Pages: 557-568
- Data Source
  KAKENHI-PROJECT-19590293
[Journal Article] Regulatory polymorphisms of multidrug resistance 1 (MDR1) gene are associated with the development of childhood acute lymphoblastic leukemia2007
- Author(s)
  Hattori, H., Suminoe, A., Wada, M., Koga, Y., Kohno, K., Okamura, J., Hara, T., and Matsuzaki, A
- Journal Title
  
  Leukemia Research 31
  
  Pages: 1633-1640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590293
[Journal Article] ATP加水分解共役型排出ポンプの構造、生理機能と疾病2007
- Author(s)
  和田守正, 藤田京子
- Journal Title
  
  生化学 79
  
  Pages: 557-568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590293
[Journal Article] Regulatery polymorphisms of multidrug resistance 1(MDRI)gene are asseciated with the deve:eprnent of childhood acute lymphoblastic leukemia2007
- Author(s)
  Hattod, H., Suminoe, A., Wada, M., Koga, Y., Kohno, K., Okamura, J, Hara, T., and Matsuzaki, A.
- Journal Title
  
  Leukemia Researvh 31
  
  Pages: 1633-1640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590293
[Journal Article] Single nucleotide polymorphisms in ABCC2 and ABCB1 genes and their clinical impact in physiology and drug response.2006
- Author(s)
  Wada, M.
- Journal Title
  
  Cancer Letters 234
  
  Pages: 40-50
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] Single nucleotide polymorphisms in ABCC2 and ABCB1 genes and their clinical impact in physiology and drug response.2006
- Author(s)
  Wada, M.
- Journal Title
  
  Cancer Letters (in press)
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] The genetic polymorphism of drug transporters : functional analysis approaches.2004
- Author(s)
  Ishikawa, T., Tsuji, A., Inui, K., Sai, Y., Anzai, N., Wada, M., Endou, H., Sumino, Y.
- Journal Title
  
  Pharmacogenomics 5
  
  Pages: 1-33
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] Dubin-Johnson-like black liver with normal bilirubin level.2004
- Author(s)
  Kobayashi, Y., Wada, M., et al.
- Journal Title
  
  J.Gastroenterol. 39
  
  Pages: 892-895
- NAID
  10013613442
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] The genetic polymorphism of drug transporters : functional analysis approaches.2004
- Author(s)
  Ishikawa, T., Wada, M., et al.
- Journal Title
  
  Pharmacogenomics 5
  
  Pages: 1-33
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] Dubin-Johnson-like black liver with normal bilirubin level.2004
- Author(s)
  Kobayashi, Y., Ishihara, T., Wada, M., Kajihara, S., Araki, J., Mifuji, R., Itani, T., Kuroda, M., Urawa, F., Kaito, M., Adachi, Y.
- Journal Title
  
  Journal of Gastroenterology 39
  
  Pages: 892-895
- NAID
  10013613442
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] Genetic polymorphism at the 5' regulatory region of MDR1 and its association with inter-individual variation of expression level in colon.2003
- Author(s)
  Taniguchi, S., Mochida.Y., Uchiumi, T., Tahira, T., Hayashi, K., Takagi, K., Shimada, M., Maehara, Y., Kuwano, H., Kono, S., Nakano, H., Kuwano, M., Wada, M.
- Journal Title
  
  Molecular Cancer Therapeutics 2
  
  Pages: 1351-1359
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] The Basic and Clinical Implication of ABC transporters, YB-1 and Angiogenesis in Human Malignancies.2003
- Author(s)
  Kuwano, M., Uchiumi, T., Hayakawa, H., Ono, M., Wada, M., Izumi, H., Kohno, K.
- Journal Title
  
  Cancer Science 94
  
  Pages: 9-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] Identification of Domains Participating in the Substrate Specificity of the Multidrug Resistance Proteins, MRP1 and MRP2.2003
- Author(s)
  Konno, T., Ebihara, T., Hisaeda, K, Uchiumi, T., Nakamura, T., Shirakusa, T., Kuwano, M., Wada, M.
- Journal Title
  
  Journal of Biological Chemistry 278
  
  Pages: 22908-22917
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] Molecular basis of inherited transport defects-, edited by S. Broer and C. A. Wagner : Canalicular multispecific organic anion transporter, ABCC22003
- Author(s)
  Wada, M., Uchiumi, T., Kuwano, M.
- Journal Title
  
  MEMBRANE TRANSPORT DISEASES -NY KluwerAcadermic/ Plenum Publishers
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] The role of P-glycoprotein in intestinal tumorigenesis : disruption of mdrla suppresses polyp formation in ApcMin/+ mice.2003
- Author(s)
  Mochida, Y., Taguchi, K., Taniguchi, S., Tsuneyoshi, M., Kuwano, H., Tsuzuki, T., Kuwano, M., Wada, M.
- Journal Title
  
  Carcinogenesis 24
  
  Pages: 1219-1224
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] The Association of DAP-kinase Hypermethylation with Early Recurrence in Superficial Bladder Cancers2002
- Author(s)
  Tada, Y., Wada, M., Taguchi, K., Mochida, Y., Kinugawa, N., Tsuneyoshi, M., Naito, S., Kuwano, M.
- Journal Title
  
  Cancer Research 62
  
  Pages: 4048-4053
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome.2002
- Author(s)
  Hashimoto, K., Uchiumi, T., Konno, T., Ebihara, T., Nakamura, T., Wada, M., Sakisaka, S., Maniwa, F., Amachi, T., Ueda, K., Kuwano M.
- Journal Title
  
  Hepatology 36
  
  Pages: 1236-1245
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] Increased expression of multidrug resistance-associated proteinsin bladder cancer during clinical course and drug resistance to doxorubicin.2002
- Author(s)
  Tada, Y., Wada, M., Migita, T., Nagayama, J., Hinoshita, E., Mochida, Y., Maehara, Y., Tsuneyoshi, M., Kuwano, M., Naito, S.
- Journal Title
  
  International Journal of Cancer 98
  
  Pages: 630-635
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] Retrovirus insertion and transcriptional activation of the multidrug resistance (mdrla) gene in leukemias treated by a chemotherapeutic agent in vivo.2001
- Author(s)
  Nagayama, J., Iino, M., Tada, Y., Kusaba, H., Kiue, A., Ohshima, K., Kuwano, M., Wada, M.
- Journal Title
  
  Blood 97
  
  Pages: 759-766
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Journal Article] Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1.
- Author(s)
  Kato Y, Kubo Y, Iwata D, Kato S, Sudo T, Sugiura T, Kagaya T, Wakayama T, Hirayama A, Sugimoto M, Sugihara K, Kaneko S, Soga T, Asano M, Tomita M, Matsui T, Wada M, Tsuji A.
- Journal Title
  
  Pharm Res (印刷中)
- NAID
  120002224385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590323
[Patent] MDR1遺伝子の5'制御領域におけるSNPs2003
- Inventor(s)
  和田守正, 桑野信彦
- Industrial Property Rights Holder
  和田守正, 桑野信彦
- Industrial Property Number
  2003-332584
- Filing Date
  2003-09-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Patent] ヒトcMOAT遺伝子とそのcDNA1996
- Inventor(s)
  和田守正, 桑野信彦
- Industrial Property Rights Holder
  和田守正, 桑野信彦
- Filing Date
  1996-09-30
- Acquisition Date
  2005-07-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142208
[Presentation] 多剤耐性タンパク質の細胞内局在化におけるリシン・リッチ領域の役割2011
- Author(s)
  南恵美、藤本京子、榎田陽介、横田貞記、和田守正
- Organizer
  第34回・日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-21590323
[Presentation] 多剤耐性タンパク質の細胞内局在化におけるリシン・リッチ領域の役割2011
- Author(s)
  南恵美、藤本京子、榎田陽介、横田貞記、和田守正
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-21590323
[Presentation] In vitro fertilization (IVF)での精子活性化培地の改良2011
- Author(s)
  田中宏光、正山征洋、和田守正
- Organizer
  第34回日本分子生物学会念会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22591810
[Presentation] Analysis of sperm ability to reach female oviduct in OAZ-t deficient mouse labeled green acrosome and red mitochondria /2010
- Author(s)
  Hiromitsu Tanaka, Masaru Okabe, Morimasa Wada, Kyoko Fujimoto, Sadaki Yokota /
- Organizer
  第33回日本分子生物学会念会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22591810
[Presentation] ApcMin/+マウスにおける腫瘍サイズ依存的遺伝子の同定と機能解析2010
- Author(s)
  藤本京子、仲西定祐、田口健一、田中宏光、安田香央里、田代康介、久原哲、和田守正
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21590323
[Presentation] Apc^<Min/+>マウスにおける腫瘍サイズ依存的遺伝子の同定と機能解析2010
- Author(s)
  藤本京子、仲西定祐、田口健一、田中宏光、安田香央里、田代康介、久原哲、和田守正
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21590323
[Presentation] Chemoprevention of intestinal cancer by P-gp inhibitors2009
- Author(s)
  Kyoko Fujita, Masa Yasunaga, Morimasa Wada
- Organizer
  Gordon Research Conference, Multi-Drug Efflux Systems
- Place of Presentation
  Galveston, Texas, USA
- Year and Date
  2009-03-23
- Data Source
  KAKENHI-PROJECT-19590293
[Presentation] Apc Min/+マウスにおける腫瘍サイズ別遺伝子発現パターンの解析2009
- Author(s)
  藤田京子、田口健一、安田香央里、田中宏光、田代康介、久原哲、和田守正
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21590323
[Presentation] Chemoprevention of intestinal cancer by P-gp inhibitors, Gordon Research Conference2009
- Author(s)
  Kyoko Fujita and Masa Yasunaga, Morimasa Wada
- Organizer
  Multi-Drug Efflux Systems
- Place of Presentation
  Galveston, Texas, USA
- Year and Date
  2009-03-23
- Data Source
  KAKENHI-PROJECT-19590293
[Presentation] 耐性克服薬による腸管腫瘍の化学予防戦略2008
- Author(s)
  和田守正
- Organizer
  第12回がん分子標的治療研究会総会
- Place of Presentation
  東京
- Year and Date
  2008-06-27
- Data Source
  KAKENHI-PROJECT-19590293
[Presentation] ApcMin/+マウスにおける腫瘍サイズの不連続分布2008
- Author(s)
  藤田京子, 安永真沙, 安田香央里, 富永由紀, 田代康介, 久原哲, 和田守正
- Organizer
  第31回日本分子生物学会年会、第81回日本生化学会大会、合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19590293
[Presentation] P糖タンパク質(P-gp)阻害剤による腸管腫瘍の化学予防効果2007
- Author(s)
  藤田京子, 安永真沙,和田守正
- Organizer
  日本分子生物学会、日本生化学会、合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19590293
[Presentation] ATP-binding cassette (ABC) transporter family as a risk factor oflife-style related diseases2007
- Author(s)
  Morimasa WADA
- Organizer
  The 21st century COE Program, International Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-19590293
[Presentation] Relevance of ABC proteins in drugdiscovery2007
- Author(s)
  Morimasa Wada, Kyoko Fujita and Masa Yasunag
- Organizer
  Asian Symposium for Pharmaceutical Science in JSPS Asian Core Program in Huis Ten Bosch,
- Place of Presentation
  SaseboSasebo
- Year and Date
  2007-10-16
- Data Source
  KAKENHI-PROJECT-19590293
[Presentation] P糖タンパク質(P-gp)阻害剤による腸管腫瘍の化学予防効果2007
- Author(s)
  藤田京子、安永真沙、和田守正
- Organizer
  日本分子生物学会、日本生化学会、合向大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19590293
[Presentation] ATP-binding cassette(ABC)transporter family as a risk factor of life-style reiated diseases2007
- Author(s)
  Morimasa WADA
- Organizer
  The 21st century COE Program, international symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-19590293
[Presentation] Relevance of ABC proteins in drug discovery2007
- Author(s)
  Morimasa Wada, Kyoko Fuiita and Masa Yasunaga
- Organizer
  Asian Symposium for Phamaceutical Science in JSPS Asian Cere Program in Huis Ten Besch
- Place of Presentation
  Huis Ten Bosch,Sasebo
- Year and Date
  2007-10-16
- Data Source
  KAKENHI-PROJECT-19590293

1. KOHNO Kimitoshi (00153479)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. FUJITA Kyoko (50435137)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
3. KUWANO Michihiko (80037431)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. ONO Mayumi (80128347)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 松崎彰信 (90238999)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. UCHIUMI Takeshi (80253798)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TANAKA Hiromitsu (10263310)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
8. FOJO Antonio t.

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TSUJIMURA Akira (40294053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. MIYAGAWA Yasushi (70362704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 達家雅明 (50216991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 大和田幸嗣 (60029816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 三井宏美 (90109942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 佐々木裕之 (30183825)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 白崎哲哉 (30264047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 原田伸透 (90264043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 古野純典 (70128015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 掛地吉弘 (80284488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 壬生隆一 (20200107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 安波洋一 (00166521)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 池田典昭 (60176097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 池田陽一 (50311840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 佐々木淳 (90122697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 住江愛子 (80335968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. LONGO Dan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. SCHLESSINGER David

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. COLE Susan P.C

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. DEELEY Roger

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. GREEN Eric

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. DANLONGO ロンゴ

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. DAVID Schles

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. SCHLESSINGER デーヴイド

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. BECK William

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. D′URSO Miche

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. SCHLESSINGE デーヴィド

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

WADA Morimasa 和田 守正

和田 守正 ワダ モリマサ

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Host-defense by excretion and it's failure generating diseasesPrincipal Investigator

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Host-defense through excretion of xenobiotics and related diseasesPrincipal Investigator

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生体防御のフロントライン:異物排出機能の破綻と病態Principal Investigator

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解毒・排出系の遺伝子多型に基づく薬剤応答、副作用の予測Principal Investigator

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Molecular structure and functional regulation of ATP-binding cassette transportersPrincipal Investigator

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解毒・排出系の遺伝子多型に基づく薬剤応答、副作用の予測Principal Investigator

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巨大ヒトゲノム導入による機能解析Principal Investigator

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WADA Morimasa 和田守正

和田守正ワダモリマサ