Kohara Kyoko 小原恭子

… Alternative Names

KOHARA Kyoko 小原恭子

小原恭子コハラキョウコ

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Researcher Number	20225478
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2026: 鹿児島大学, 共同獣医学部, 特任教授 2020 – 2023: 鹿児島大学, 農水産獣医学域獣医学系, 教授 2015 – 2016: 鹿児島大学, 農水産獣医学域獣医学系, 教授 2012 – 2014: 鹿児島大学, 共同獣医学部, 教授 2013: 鹿児島大学, 獣医学部, 教授 … More 2011: 鹿児島大学, 農学部, 教授 2006 – 2007: 熊本大学, 医学薬学研究部, 特任教授 2000 – 2005: The Tokyo Metropolitan Institute of Medical Science, Research Scientist, 医科学研究所, 講師 1999: THE TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE, Department of Microbiology and Cell Biology, Researcher, 東京都臨床医学総合研究所, 研究員 1999: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 1998: 財団法人東京都臨床医学総合研究所, 放射線医学研究部門, 研究員 1997: (財)東京都臨床医学総合研究所, 放射線医学研究部門, 研究員 1997: The Tokyo Metropolitan Institute of Medical Science, Department of Radiation Res, 放射線医学研究部門, 研究員 1996: 財団法人東京都臨床医学総合研究所, 微生物研究部門, 研究員 1993: 財団法人東京都臨床医学総合研究所, 微生物研究部門, 研究員 Less
Review Section/Research Field	Principal Investigator Laboratory animal science / Basic Section 42030:Animal life science-related / Veterinary medical science / Applied veterinary science / Virology / Virology / Biological Sciences / Laboratory animal science / Molecular biology Except Principal Investigator Biological Sciences … More / Basic veterinary science/Basic zootechnical science / Virology / Sections That Are Subject to Joint Review: Basic Section45050:Physical anthropology-related , Basic Section45060:Applied anthropology-related / Basic Section 45060:Applied anthropology-related / Basic Section 45050:Physical anthropology-related / Laboratory animal science Less
Keywords	Principal Investigator HCV / IRES / C型肝炎ウイルス / FMDV / WAF1 / CIP1 / p21 / Cre / ツパイ / PTB … More / ピクノジュノール / HBV / ゲノム / KOマウス / USP31 / PKD1L3 / PYC / shRNA / CSFV / MDCK細胞 / MDBK細胞 / CPK細胞 / 細胞株 / ITAF45 / 4E-BP1 / 宿主因子 / Deliver vector / vaccine / Morbilli virus / New Reverse Genetics method / デリバリーベクター / ワクチン / モービリウイルス / 新リバースジェネティクス法 / Mechanism of Carcinogenesis / HCV Tg mouse / HCV expressing cell line / loxP expression system / 腫瘍原性 / 発癌機序 / Tgマウス / HCV発現細胞株 / loxP発現システム / microRNA / トランスジェニックマウス / Ｂリンパ腫 / miR-26b / NF-kB / A20 / microarray / Bリンパ腫 / モノクローナル抗体 / AFP / 肝がん / リバースジェネティクス法 / アポトーシス / Fas / グループIIHCV / グループIHCV / internal initiation … More Except Principal Investigator 感染性cDNAクローン / C型肝炎ウイルス / IL-8 / IL-6 / GM-CSF / トランスジェニックマウス / トランスフォーム / C型肝炎ウィルス / エコツーリズム / リスク評価 / スピルオーバー / 大型類人猿 / ウイルス感染症 / heparin sulfate / receptor / transgenic mice / measles virus / ヘパリン硫酸 / レセプター / トランジェニックマウス / 麻疹ウイルス / canine distemper virus / rinderpest virus / new reverse genetics / mononega virus / 組み換えウイルス / レプリコン / 欠損ウイルス / RPV / リバースジェネティクス / CDV / 新リバースジェネティクス系 / イヌジステンパーウイルス / 牛疫ウイルス / リバースジェネティクス系 / モノネガウイルス / replication / pathogenesis / infectious cDNA / HCV / HCV cDNAクローン / シグナル伝達 / インターフェロン / sendai virus / canine / cytokine / アジュバント / センダイウイルス / イヌ / サイトカイン / HCV like-particle / Immuno-electron microscopic study / Infectious clone / HCV cDNA / Hepatitis C virus / 遺伝子複製 / ウイルス様粒子 / 遺伝子複製効率 / 免疫電子顕微鏡法 / 全遺伝子のcDNA / p53蛋白質 / WRN蛋白質 / 持続感染複製 / 肝がん / 発癌 / C型肝炎 Less

Risk Assessment of Infectious Diseases in Great Apes: Development of an On-Site Testing System and Analysis of Transmission Dynamics
- Principal Investigator
  
  藤田志歩
- Project Period (FY)
  2026 – 2030
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 45050:Physical anthropology-related
  Basic Section 45060:Applied anthropology-related
  Sections That Are Subject to Joint Review: Basic Section45050:Physical anthropology-related , Basic Section45060:Applied anthropology-related
- Research Institution
  Kagoshima University
Basic study for identification of common FMDV, CSFV IRES factors and its applicationPrincipal Investigator
- Principal Investigator
  
  Kohara Kyoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Kagoshima University
Foot and mouth disease virus specific translation inhibition and application for development of disease resistant livestockPrincipal Investigator
- Principal Investigator
  
  Kohara Kyoko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Veterinary medical science
- Research Institution
  Kagoshima University
ツパイゲノム情報に基づく肝炎ウイルス動物感染系の確立に関する研究Principal Investigator
- Principal Investigator
  
  小原恭子
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Laboratory animal science
- Research Institution
  Kagoshima University
Impact of hepatitis C virus infection in B cells on pathogenesisPrincipal Investigator
- Principal Investigator
  
  KOHARA Kyoko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kagoshima University
C型肝炎ウイルスによる遺伝子変異蓄積及び細胞不死化機序の解析
- Principal Investigator
  
  小原道法
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Establishment and analysis of measles virus-susceptible transgenic mice.
- Principal Investigator
  
  MIURA Ryuichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
新組み換え技術を用いたがん治療用麻疹ウイルスベクターの開発Principal Investigator
- Principal Investigator
  
  小原恭子
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Development of the new vaccine and a delivery vector by the recombination Morbilli virus.Principal Investigator
- Principal Investigator
  
  KOHARA Kyoko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  The University of Tokyo
肝炎ウイルスの持続感染制御因子および肝炎肝がん発症機序の解析とその制御
- Principal Investigator
  
  小原道法
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
C型肝炎ウイルスのツパイ感染実験モデル系の開発Principal Investigator
- Principal Investigator
  
  小原恭子
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
肝炎ウィルスの感染複製制御因子および肝炎肝がん発症機序の解析とその制御
- Principal Investigator
  
  KOHARA Michinori
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Analysis of the species specific pathogenicity of morbillivirus by reverse genetics.
- Principal Investigator
  
  KAI Chieko
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  The University of Tokyo
Development of Immune Induction System by Using The Novel Virus Vectors of Cytokines
- Principal Investigator
  
  KAI Chieko, 高橋英司
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  The University of Tokyo
Characterization of HCV replication and pathogenesis in animal model
- Principal Investigator
  
  KOHARA Michinori
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Virology
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
Modification of Cell Growth Regulation by Hepatitis C virusPrincipal Investigator
- Principal Investigator
  
  KOHARA Kyoko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH, THE TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE
Analysis of persistent infection mechanism of RNA virus
- Principal Investigator
  
  KOHARA Michinori
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
C型肝炎ウイルスの蛋白合成開始を支配するRNA領域と開始因子の解析Principal Investigator
- Principal Investigator
  
  小原恭子
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research

All 2023 2022 2021 2020 2017 2016 2015 2014 2013 2012 2011 2007 Other

All Journal Article Presentation Book Patent

[Book] 生命科学のためのウイルス学（監訳　下遠野邦忠、瀨谷司）2015
- Author(s)
  小原恭子、小澤真（分担著者）
- Total Pages
  332
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-13F03079
[Book] 肝臓2011
- Author(s)
  小原恭子、小原道法
- Total Pages
  5
- Publisher
  「疾患モデルマウス：表現型解析指南(中山書店）」
- Data Source
  KAKENHI-PROJECT-23590547
[Book] HCVの病原性発現に関与するウイルス因子とその機能2011
- Author(s)
  小原恭子、棟方翼、小原道法
- Total Pages
  6
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-23590547
[Book] C型肝炎ウイルスによる免疫攪乱と炎症発がん2011
- Author(s)
  小原道法、小原恭子
- Total Pages
  7
- Publisher
  Bio Clinica
- Data Source
  KAKENHI-PROJECT-23590547
[Book] 肝臓, 疾患モデルマウス:表現型解析指南2011
- Author(s)
  小原恭子、小原道法
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23590547
[Book] 新時代のウイルス性肝炎学, 日本臨床69巻増刊4別刷, HCVの病原性発現に関与するウイルス因子とその機能II C型肝炎C型肝炎ウイルス感染における免疫応答と感染防御機構2011
- Author(s)
  小原恭子、棟方翼、小原道法
- Data Source
  KAKENHI-PROJECT-23590547
[Book] BIO Clinica 26 (10), C型肝炎ウイルスによる免疫攪乱と炎症発がん2011
- Author(s)
  小原道法、小原恭子
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] Effects of neddylation on viral infection: an overview.2023
- Author(s)
  Kayesh MEH, Kohara M, Tsukiyama-Kohara K
- Journal Title
  
  Arch Virol.
  
  Volume: 169 Issue: 1 Pages: 6-6
- DOI
  10.1007/s00705-023-05930-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Tree shrew cytochrome P450 2E1 is a functional enzyme that metabolises chlorzoxazone and p-nitrophenol.2023
- Author(s)
  Ushirozako G, Murayama N, Tsukiyama-Kohara K, Yamazaki H, Uno Y
- Journal Title
  
  Xenobiotica.
  
  Volume: 53 Issue: 10-11 Pages: 573-580
- DOI
  10.1080/00498254.2023.2280996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Increasing Dengue Burden and Severe Dengue Risk in Bangladesh: An Overview.2023
- Author(s)
  Kayesh MEH, Khalil I, Kohara M, Tsukiyama-Kohara K.
- Journal Title
  
  Trop Med Infect Dis.
  
  Volume: 8 Issue: 1 Pages: 32-32
- DOI
  10.3390/tropicalmed8010032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Investigation of koala retrovirus in captive koalas with pneumonia and comparative analysis of subtype distribution.2023
- Author(s)
  Akter L, Hashem MA, Rakib TM, Rashid MHO, Hossain KA, Akhter R, Utsunomiya M, Kitab B, Hifumi T, Miyoshi N, Maetani F, Tsukiyama-Kohara K.
- Journal Title
  
  Arch Virol.
  
  Volume: 168 Issue: 12 Pages: 298-298
- DOI
  10.1007/s00705-023-05928-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Novel cytochrome P450 1 (CYP1) genes in tree shrews are expressed and encode functional drug-metabolizing enzymes2023
- Author(s)
  Uno Yasuhiro、Noda Yutaro、Murayama Norie、Tsukiyama-Kohara Kyoko、Yamazaki Hiroshi
- Journal Title
  
  Comparative Biochemistry and Physiology Part C
  
  Volume: 265 Pages: 109534-109534
- DOI
  10.1016/j.cbpc.2022.109534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06434, KAKENHI-PROJECT-20H03164
[Journal Article] A Novel, Comprehensive A129 Mouse Model for Investigating Dengue Vaccines and Evaluating Pathogenesis2023
- Author(s)
  Ngwe Tun MM, Nwe KM, Balingit JC, Takamatsu Y, Inoue S, Pandey BD, Urano T, Kohara M, Tsukiyama-Kohara K, Morita K
- Journal Title
  
  Vaccines (Basel)
  
  Volume: 11(12):1857 Issue: 12 Pages: 59-68
- DOI
  10.3390/vaccines11121857
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07059, KAKENHI-PROJECT-20H03164
[Journal Article] Newly identified cytochrome P450 3A genes of tree shrews and pigs are expressed and encode functional enzymes2023
- Author(s)
  Uno Yasuhiro、Jikuya Shiori、Noda Yutaro、Oguchi Asuka、Murayama Norie、Kawaguchi Hiroaki、Tsukiyama-Kohara Kyoko、Yamazaki Hiroshi
- Journal Title
  
  Comparative Biochemistry and Physiology Part C
  
  Volume: 267 Pages: 109579-109579
- DOI
  10.1016/j.cbpc.2023.109579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06434, KAKENHI-PROJECT-20H03164
[Journal Article] Molecular insights of a CBP/β-catenin-signaling inhibitor on nonalcoholic steatohepatitis-induced liver fibrosis and disorder2023
- Author(s)
  Yamaji Kenzaburo、Iwabuchi Sadahiro、Tokunaga Yuko、Hashimoto Shinichi、Yamane Daisuke、Toyama Sakiko、Kono Risa、Kitab Bouchra、Tsukiyama-Kohara Kyoko、Osawa Yosuke、Hayashi Yukiko、Hishima Tsunekazu、Tateno Chise、Kimura Kiminori、Okanoue Takeshi、Kohara Michinori
- Journal Title
  
  Biomedicine Pharmacotherapy
  
  Volume: 166 Pages: 115379-115379
- DOI
  10.1016/j.biopha.2023.115379
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06981, KAKENHI-PROJECT-21K08014, KAKENHI-PROJECT-20H03164, KAKENHI-PROJECT-23K21382
[Journal Article] Development of short hairpin RNA expression vectors targeting the internal ribosomal entry site of the classical swine fever virus genomic RNA.2023
- Author(s)
  Okamoto R, Ito N, Ide Y, Kitab B, Sakoda Y, Tsukiyama-Kohara K
- Journal Title
  
  BMC Biotechnol.
  
  Volume: 23 Issue: 1 Pages: 37-37
- DOI
  10.1186/s12896-023-00805-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] TLR agonists as vaccine adjuvants in the prevention of viral infections: an overview.2023
- Author(s)
  Kayesh MEH, Kohara M, Tsukiyama-Kohara K.
- Journal Title
  
  Front Microbiol.
  
  Volume: 14 Pages: 1249718-1249718
- DOI
  10.3389/fmicb.2023.1249718
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Regulatory Role of Ribonucleotide Reductase Subunit M2 in Hepatocyte Growth and Pathogenesis of Hepatitis C Virus.2023
- Author(s)
  Kitab B, Tsukiyama-Kohara K
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 24 Issue: 3 Pages: 2619-2619
- DOI
  10.3390/ijms24032619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Newly Identified Tree Shrew Cytochrome P450 2A13 (CYP2A13) is Expressed in Liver and Lung and Encodes a Functional Drug-Metabolizing Enzyme Similar to Dog CYP2A13 and Pig CYP2A192023
- Author(s)
  Ushirozako Genki、Noda Yutaro、Murayama Norie、Kawaguchi Hiroaki、Tsukiyama-Kohara Kyoko、Yamazaki Hiroshi、Uno Yasuhiro
- Journal Title
  
  Drug Metabolism and Disposition
  
  Volume: - Issue: 5 Pages: 610-617
- DOI
  10.1124/dmd.122.001152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06434, KAKENHI-PROJECT-20H03164
[Journal Article] Mammalian animal models for dengue virus infection: a recent overview.2022
- Author(s)
  Kayesh MEH, Tsukiyama-Kohara K.
- Journal Title
  
  Arch Virol.
  
  Volume: 167 Issue: 1 Pages: 31-44
- DOI
  10.1007/s00705-021-05298-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Characterization of host factors associated with the internal ribosomal entry sites of foot-and-mouth disease and classical swine fever viruses.2022
- Author(s)
  Ide Y, Kitab B, Ito N, Okamoto R, Tamura Y, Matsui T, Sakoda Y, Tsukiyama-Kohara K.
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 6709-6709
- DOI
  10.1038/s41598-022-10437-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Subtype distribution and expression of the koala retrovirus in the Japanese zoo koala population.2022
- Author(s)
  Hashem MA, Kayesh MEH, Maetani F, Goto A, Nagata N, Kasori A, Imanishi T, Tsukiyama-Kohara K
- Journal Title
  
  Infect Genet Evol.
  
  Volume: 102 Pages: 105297-105297
- DOI
  10.1016/j.meegid.2022.105297
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Newly identified tree shrew cytochrome P450 2B6 (CYP2B6) and pig CYP2B6b are functional drug-metabolising enzymes2022
- Author(s)
  Uno Yasuhiro、Ushirozako Genki、Uehara Shotaro、Murayama Norie、Fujiki Yuki、Kawaguchi Hiroaki、Tsukiyama-Kohara Kyoko、Yamazaki Hiroshi
- Journal Title
  
  Xenobiotica
  
  Volume: 52 Issue: 7 Pages: 687-696
- DOI
  10.1080/00498254.2022.2141153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06434, KAKENHI-PROJECT-20H03164
[Journal Article] Toll-like Receptor Response to Hepatitis C Virus Infection: A Recent Overview.2022
- Author(s)
  Kayesh MEH, Kohara M, Tsukiyama-Kohara K.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 23 Issue: 10 Pages: 5457-5457
- DOI
  10.3390/ijms23105475
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Molecular Insights into Innate Immune Response in Captive Koala Peripheral Blood Mononuclear Cells Co-Infected with Multiple Koala Retrovirus Subtypes.2022
- Author(s)
  Kayesh MEH, Hashem MA, Maetani F, Goto A, Nagata N, Kasori A, Imanishi T, Tsukiyama-Kohara K.
- Journal Title
  
  Pathogens
  
  Volume: 11 Issue: 8 Pages: 911-911
- DOI
  10.3390/pathogens11080911
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] 1.Characterization of host factors commonly working in the internal ribosomal entry sites of foot-and-mouth disease and classical swine fever virus.2022
- Author(s)
  Yutaro Ide, Bouchra Kitab, Nobumasa Ito, Riai Okamoto, Yui Tamura, Takafumi Matsui, Yoshihiro Sakoda, and Kyoko Tsukiyama-Kohara.
- Journal Title
  
  Scientific Reports
  
  Volume: accepted
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Non-primate hepacivirus transmission and prevalence: Novel findings of virus circulation in horses and dogs in Morocco.2021
- Author(s)
  Abbadi I, Lkhider M, Kitab B, Jabboua K, Zaidane I, Haddaji A, Nacer S, Matsuu A, Pineau P, Tsukiyama-Kohara K, Benjelloun S, Ezzikouri S
- Journal Title
  
  Infect Genet Evol.
  
  Volume: 93 Pages: 104975-104975
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Basic Study for Vaccine Development Targeting Virus Infections.2021
- Author(s)
  Tsukiyama-Kohara K, Kohara M.
- Journal Title
  
  Viruses
  
  Volume: 14 Issue: 1 Pages: 57-57
- DOI
  10.3390/v14010057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] An Overview of Recent Insights into the Response of TLR to SARS-CoV-2 Infection and the Potential of TLR Agonists as SARS-CoV-2 Vaccine Adjuvants.2021
- Author(s)
  Kayesh MEH, Kohara M, Tsukiyama-Kohara K.
- Journal Title
  
  Viruses
  
  Volume: 18 Issue: 11 Pages: 2302-2302
- DOI
  10.3390/v13112302
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Recent Insights Into the Molecular Mechanism of Toll-Like Receptor Response to Dengue Virus Infection.2021
- Author(s)
  Kayesh MEH, Kohara M, Tsukiyama-Kohara K.
- Journal Title
  
  Front. Microbiol.
  
  Volume: 16 Pages: 744233-744233
- DOI
  10.3389/fmicb.2021.744233
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Toll-Like Receptor Expression Profiles in Koala (Phascolarctos cinereus) Peripheral Blood Mononuclear Cells Infected with Multiple KoRV Subtypes.2021
- Author(s)
  Kayesh MEH, Hashem MA, Tsukiyama-Kohara K.
- Journal Title
  
  Animals
  
  Volume: 11 Issue: 4 Pages: 983-983
- DOI
  10.3390/ani11040983
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Koala retrovirus (KoRV) subtypes and their impact on captive koala (Phascolarctos cinereus) health.2021
- Author(s)
  Hashem MA, Kayesh MEH, Maetani F, Eiei T, Mochizuki K, Ochiai S, Ito A, Ito N, Sakurai H, Asai T, Tsukiyama-Kohara K
- Journal Title
  
  Arch Virol.
  
  Volume: 166 Issue: 7 Pages: 1893-1901
- DOI
  10.1007/s00705-021-05078-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Metagenomic identification, sequencing, and genome analysis of porcine hepe-astroviruses (bastroviruses) in porcine feces in Japan.2021
- Author(s)
  Nagai M, Okabayashi T, Akagami M, Matsuu A, Fujimoto Y, Hashem MA, Mekata H, Nakao R, Matsuno K, Katayama Y, Oba M, Omatsu T, Asai T, Nakagawa K, Ito H, Madarame H, Kawai K, Ito T, Nonaka N, Tsukiyama-Kohara K, Inoshima Y, Mizutani T, Misawa N
- Journal Title
  
  Infect Genet Evol.
  
  Volume: 88 Pages: 104664-104664
- DOI
  10.1016/j.meegid.2020.104664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Development and Characterization of a Highly Sensitive NanoLuciferase-Based Immunoprecipitation System for the Detection of Anti-Influenza Virus HA Antibodies.2021
- Author(s)
  Honda T, Gomi S, Yamane D, Yasui F, Yamamoto T, Munakata T, Itoh Y, Ogasawara K, Sanada T, Yamaji K, Yasutomi Y, Tsukiyama-Kohara K, Kohara M.
- Journal Title
  
  mSphere
  
  Volume: 12 Issue: 3
- DOI
  10.1128/msphere.01342-20
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164, KAKENHI-PROJECT-20K07531, KAKENHI-PROJECT-19K16680, KAKENHI-PROJECT-23K21382
[Journal Article] Toll-Like Receptor and Cytokine Responses to Infection with Endogenous and Exogenous Koala Retrovirus, and Vaccination as a Control Strategy.2021
- Author(s)
  Kayesh MEH, Hashem MA, Tsukiyama-Kohara K.
- Journal Title
  
  Curr Issues Mol Biol.
  
  Volume: 43 Issue: 1 Pages: 52-64
- DOI
  10.3390/cimb43010005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Longer poly(U) stretches in the 3′UTR are essential for replication of the hepatitis C virus genotype 4a clone in in vitro and in vivo.2021
- Author(s)
  Asako Takagi, Yutaka Amako, Daisuke, Yamane, Bouchra Kitab, Yuko Tokunaga, Ahmed El-Gohary, Michinori Kohara, Kyoko Tsukiyama-Kohara
- Journal Title
  
  Front. Microbiol.
  
  Volume: 12 Pages: 76816-76816
- DOI
  10.3389/fmicb.2021.764816
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03164, KAKENHI-PROJECT-23K21382
[Journal Article] Coronavirus disease 2019-Historical context, virology, pathogenesis, immunotherapy, and vaccine development.2020
- Author(s)
  Ezzikouri S, Nourlil J, Benjelloun S, Kohara M, Tsukiyama-Kohara K.
- Journal Title
  
  Hum. Vaccine Immunother.
  
  Volume: 16 Issue: 12 Pages: 2992-3000
- DOI
  10.1080/21645515.2020.1787068
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Structure-guided discovery approach identifies potential lead compounds targeting Mpro of SARS-CoV-2.2020
- Author(s)
  Elmessaoudi-Idrissi M, Tsukiyama-Kohara K, Nourlil J, Kettani A, Windisch MP, Kohara M, Malik YS, Dhama K, Benjelloun S, Ezzikouri S.
- Journal Title
  
  Virusdisease
  
  Volume: 21 Issue: 4 Pages: 1-5
- DOI
  10.1007/s13337-020-00627-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Transmission of Koala Retrovirus from Parent Koalas to a Joey in a Japanese Zoo.2020
- Author(s)
  Hashem MA, Maetani F, Kayesh MEH, Eiei T, Mochizuki K, Ito A, Sakurai H, Asai T, Tsukiyama-Kohara K.
- Journal Title
  
  J. Virol.
  
  Volume: 94 Issue: 11
- DOI
  10.1128/jvi.00019-20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Nanobodies: an unexplored opportunity to combat COVID-19.2020
- Author(s)
  Ezzikouri S, Nourlil J, Tsukiyama-Kohara K, Kohara M, El Ossmani H, Windisch MP, Benjelloun S.
- Journal Title
  
  J. Biomol Struct. Dyn.
  
  Volume: 10 Issue: 7 Pages: 1-5
- DOI
  10.1080/07391102.2020.1845801
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Koala retrovirus epidemiology, transmission mode, pathogenesis, and host immune response in koalas (Phascolarctos cinereus): a review.2020
- Author(s)
  Kayesh MEH, Hashem MA, Tsukiyama-Kohara K.
- Journal Title
  
  Arch Virol.
  
  Volume: 165 Issue: 11 Pages: 2409-2417
- DOI
  10.1007/s00705-020-04770-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Pathological and genetic aspects of spontaneous mammary gland tumor in Tupaia belangeri (Tree shrew)2020
- Author(s)
  Chi Hai-Ying, Yuuki Tanaka, Tatsuro Hifumi, Ko-ichiro Shoji, Mohammad Enamu Hoque Kayesh, Md Abul Hashem, Bouchra Kitab, Takahiro Sanada, Tomoko Fujiyuki, Misako Yoneda, Hitoshi Hatai, Akira Yabuki, Noriaki Miyoshi, Chieko Kai, Michinori Kohara, Kyoko Tsukiyama-Kohara
- Journal Title
  
  PLoS One
  
  Volume: 15(5) Issue: 5 Pages: e0233232-e0233232
- DOI
  10.1371/journal.pone.0233232
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19277, KAKENHI-PROJECT-19K16680, KAKENHI-PROJECT-16H02587, KAKENHI-PROJECT-20H03164
[Journal Article] Macrocyclic peptides exhibit antiviral effects against influenza virus HA and prevent pneumonia in animal models2020
- Author(s)
  Saito, M Itoh Y, Yasui F, Munakata T, Yamane D, Ozawa M, Ito R, Katoh T, Ishigaki H, Nakayama M, Shichinohe S, Yamaji K, Yamamoto N, Ikejiri A, Honda T, Sanada T, Sakoda Y, Kida H, Le TH, Kawaoka Y, Ogasawara Tsukiyama-Kohara T, Suga H, & Kohara M
- Journal Title
  
  Nature Comunications
  
  Volume: - Issue: 1 Pages: 2654-2654
- DOI
  10.1038/s41467-021-22964-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164, KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-23K21382
[Journal Article] CD4, CD8b, and Cytokines Expression Profiles in Peripheral Blood Mononuclear Cells Infected with Different Subtypes of KoRV from Koalas (Phascolarctos cinereus) in a Japanese Zoo.2020
- Author(s)
  Kayesh MEH, Hashem MA, Maetani F, Eiei T, Mochizuki K, Ochiai S, Ito A, Ito N, Sakurai H, Asai T, Tsukiyama-Kohara K.
- Journal Title
  
  Viruses
  
  Volume: 12 Issue: 12 Pages: 1415-1415
- DOI
  10.3390/v12121415
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03164
[Journal Article] Susceptibility and initial immune response of Tupaia belangeri cells to dengue virus infection2017
- Author(s)
  Kayesh MEH, Kitab B, Sanada T, Hayasaka D, Morita K, Kohara M, *Tsukiyama-Kohara K.
- Journal Title
  
  Infect Genet Evol.
  
  Volume: 51 Pages: 203-210
- DOI
  10.1016/j.meegid.2017.04.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01272, KAKENHI-PROJECT-15H04739, KAKENHI-PROJECT-15K14871, KAKENHI-PROJECT-15K15146, KAKENHI-PROJECT-17K15709, KAKENHI-PROJECT-16H05174
[Journal Article] IRES-mediated translation of foot-and-mouth disease virus (FMDV) in cultured cells derived from FMDV-susceptible and -insusceptible animals2016
- Author(s)
  T. Kanda, M. Ozawa, K. Tsukiyama-Kohara
- Journal Title
  
  BMC Vet Res
  
  Volume: 12 Issue: 1 Pages: 66-66
- DOI
  10.1186/s12917-016-0694-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670227, KAKENHI-PROJECT-15K14871
[Journal Article] Contribution of the interaction between the rabies virus P protein and I-kappa B kinase e; to the inhibition of type I IFN induction signalling.2016
- Author(s)
  Masatani T, Ozawa M, Yamada K, Ito N, Horie M, Matsuu A, Okuya K, Tsukiyama-Kohara K, Sugiyama M, Nishizono A.
- Journal Title
  
  J Gen Virol.
  
  Volume: 97 Issue: 2 Pages: 316-326
- DOI
  10.1099/jgv.0.000362
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14871, KAKENHI-PROJECT-26850183, KAKENHI-PROJECT-25660225, KAKENHI-PROJECT-26670227, KAKENHI-PROJECT-16H05833, KAKENHI-PROJECT-16K10506
[Journal Article] Establishment of an intermittent cold stress model using <i>Tupaia belangeri</i> and evaluation of compound C737 targeting neuron-restrictive silencer factor2016
- Author(s)
  Hai-Ying C, Nagano K, Ezzikouri S, Yamaguchi C, Kayesh ME, Rebbani K, Kitab B, Nakano H, Kouji H, Kohara M, Tsukiyama-Kohara K.
- Journal Title
  
  Exp. Anim.
  
  Volume: 65 Issue: 3 Pages: 285-292
- DOI
  10.1538/expanim.15-0123
- NAID
  130006882368
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14871
[Journal Article] HCV-Induced Oxidative Stress: Battlefield-Winning Strategy.2016
- Author(s)
  Rebbani K, Tsukiyama-Kohara K.
- Journal Title
  
  Oxid Med Cell Longev.
  
  Volume: 2016 Issue: 1 Pages: 7425628-7425628
- DOI
  10.1155/2016/7425628
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14871
[Journal Article] Supplementing Conventional Treatment with Pycnogenol May Improve Hepatitis C Virus-Associated Type 2 Diabetes: A Mini Review.2016
- Author(s)
  Ezzikouri S, Jadid FZ, Hamdi S, Wakrim L, Tsukiyama-Kohara K, Benjelloun S
- Journal Title
  
  J Clin Transl Hepatol.
  
  Volume: 4 Pages: 228-233
- DOI
  10.14218/jcth.2016.00021
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14871
[Journal Article] Molecular epidemiological study of adenovirus infecting western lowland gorillas and humans in and around Moukalaba-Doudou National Park (Gabon).2016
- Author(s)
  Nze-Nkogue C, Horie M, Fujita S, Ogino M, Kobayashi Y, Mizukami K, Masatani T, Ezzikouri S, Matsuu A, Mizutani T, Ozawa M, Yamato O, Ngomanda A, Yamagiwa J, Tsukiyama-Kohara K
- Journal Title
  
  Virus Genes
  
  Volume: 52 Issue: 5 Pages: 671-678
- DOI
  10.1007/s11262-016-1360-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24255010, KAKENHI-PROJECT-15K14871, KAKENHI-PROJECT-26850187, KAKENHI-PROJECT-26850183
[Journal Article] Isolation and characterization of influenza A viruses from environmental water at an overwintering site of migratory birds in Japan.2015
- Author(s)
  Okuya K, Kawabata T, Nagano K, Tsukiyama-Kohara K, Kusumoto I, Takase K, Ozawa M.
- Journal Title
  
  Arch Virol.
  
  Volume: 160 Issue: 12 Pages: 3037-3052
- DOI
  10.1007/s00705-015-2610-0
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14871, KAKENHI-PROJECT-26670227
[Journal Article] Efficient isolation of Swine influenza viruses by age-targeted specimen collection.2015
- Author(s)
  Ozawa M, Matsuu A, Yonezawa K, Igarashi M, Okuya K, Kawabata T, Ito K, Tsukiyama-Kohara K, Taneno A, Deguchi E.
- Journal Title
  
  J Clin Microbiol. 2015 Apr;53(4):1331-8.
  
  Volume: 53 Issue: 4 Pages: 1331-1338
- DOI
  10.1128/jcm.02941-14
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14871, KAKENHI-PROJECT-26670227, KAKENHI-PROJECT-25280080
[Journal Article] Genetic and serological surveillance for non-primate hepacivirus in horses in Japan2015
- Author(s)
  Aya Matsuu, Seiji Hobo, Kunihide Ando, Takashi Sanekata, Fumio Sato, Yoshiro Endo, Tomohiko Amaya, Tomohiro Osaki, Masayuki Horie, Tatsunori Masatani, Makoto Ozawa, Kyoko Tsukiyama-Kohara
- Journal Title
  
  Veterinary Microbiology
  
  Volume: 179 Issue: 3-4 Pages: 219-227
- DOI
  10.1016/j.vetmic.2015.05.028
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26450430, KAKENHI-PROJECT-15K14871, KAKENHI-PROJECT-26850183, KAKENHI-PROJECT-26670227
[Journal Article] Full genome sequences of torque teno sus virus strains that coinfected a pig with postweaning multisystemic wasting syndrome in Japan: implications for genetic diversity.2015
- Author(s)
  Ozawa M, Kawabata T, Okuya K, Nagano K, Kanda T, Kanazawa N, Tsukiyama-Kohara K, Taneno A, Deguchi E.
- Journal Title
  
  Arch Virol.
  
  Volume: 160 Issue: 12 Pages: 3067-3074
- DOI
  10.1007/s00705-015-2593-x
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14871, KAKENHI-PROJECT-26670227
[Journal Article] Efficacy of Recombinant Canine Distemper Virus Expressing Leishmania Antigen against Leishmania Challenge in Dogs.2015
- Author(s)
  Miura R, Kooriyama T, Yoneda M, Takenaka A, Doki M, Goto Y, Sanjoba C, Endo Y, Fujiyuki T, Sugai A, Tsukiyama-Kohara K, Matsumoto Y, Sato H, Kai C.
- Journal Title
  
  PLoS Negl Trop Dis.
  
  Volume: 9 Issue: 7 Pages: e0003914-e0003914
- DOI
  10.1371/journal.pntd.0003914
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14871, KAKENHI-PROJECT-25450421
[Journal Article] Inhibitory Effects of Pycnogenol on Hepatitis C Virus Replication.2015
- Author(s)
  Ezzikouri S, Nishimura T, Kohara M, Benjelloun S, Kino Y, Inoue K, Matsumori A, Tsukiyama-Kohara K
- Journal Title
  
  Antiviral Research
  
  Volume: 113C Pages: 93-102
- DOI
  10.1016/j.antiviral.2014.10.017
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13F03079, KAKENHI-PROJECT-24390117, KAKENHI-PUBLICLY-25114712
[Journal Article] Resistance to cyclosporin A derives from mutations in Hepatitis C virus nonstructural proteins2014
- Author(s)
  Arai, M., Tsukiyama-Kohara, K., Takagi, A., Tobita, Y., Inoue, K., Kohara, M.
- Journal Title
  
  BBRC
  
  Volume: accepted
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] Resistance to cyclosporin A derives from mutations in hepatitis C virus nonstructural proteins.2014
- Author(s)
  Arai M, Tsukiyama-Kohara K, Takagi A, Tobita Y, Inoue K, Kohara M
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 23 Issue: 1 Pages: 56-62
- DOI
  10.1016/j.bbrc.2014.04.053
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13F03079, KAKENHI-PROJECT-24390117, KAKENHI-PUBLICLY-25114712
[Journal Article] Recent insights into hepatitis B virus-host interactions.2014
- Author(s)
  Ezzikouri S, Ozawa M, Kohara M, Elmdaghri N, Benjelloun S, Tsukivama-Kohara K.
- Journal Title
  
  Journal of Medical Virology
  
  Volume: 86 Issue: 6 Pages: 925-32
- DOI
  10.1002/jmv.23916
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03079, KAKENHI-PROJECT-23590547, KAKENHI-PROJECT-24390117, KAKENHI-PROJECT-24658245, KAKENHI-PUBLICLY-25114712, KAKENHI-PROJECT-26670227
[Journal Article] Tupaia belangeri as an Experimental Animal Model for Viral Infection.2014
- Author(s)
  Tsukiyama-Kohara K, Kohara M
- Journal Title
  
  Experimental Animal
  
  Volume: 63 Pages: 367-374
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13F03079
[Journal Article] Recent insights into hepatitis B virus-host interactions.2014
- Author(s)
  Ezzikouri S, Ozawa M, Kohara M, Elmdaghri N, Benjelloun S, Tsukiyama-Kohara K.
- Journal Title
  
  J Med Virol.
  
  Volume: 86 Pages: 925-932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] Toll-like receptor 4 and hepatitis B infection: molecular mechanisms and pathogenesis.2014
- Author(s)
  Zare-Bidaki M1, Tsukiyama-Kohara K, Kazemi Arababadi M
- Journal Title
  
  Viral Immunolgy
  
  Volume: 27 Issue: 7 Pages: 321-326
- DOI
  10.1089/vim.2014.0039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03079
[Journal Article] B-Cell-Intrinsic Hepatitis C Virus Expression Leads to B-Cell-Lymphoma genesis and Induction of NF-κB Signalling2014
- Author(s)
  Kasama Y, Mizukami T, Kusunoki H, Peveling-Oberhag J, Nishito Y, Ozawa M, Kohara M, Mizuochi T. Tsukiyama-Kohara K.
- Journal Title
  
  PLoS One
  
  Volume: 9(3)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03079
[Journal Article] B-cell-intrinsic Hepatitis C virus expression leads to B-cell-lymphomagenesis and induction of NF-κB signalling.2014
- Author(s)
  Kasama Y, Mizukami T, Kusunoki H, Peveling-Oberhag J, Nishito Y, Ozawa M, Kohara M, Mizuochi T, Tsukiyama-Kohara K.
- Journal Title
  
  PLoS One
  
  Volume: 9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] B-cell-intrinsic hepatitis C virus expression leads to B-cell-lymphomagenesis and induction of NF-κB signalling2014
- Author(s)
  Kasama Y, Mizukami T, Kusunoki H, Peveling-Oberhag J, Nishito Y, Ozawa M, Kohara M, Mizuochi T, Tsukiyama-Kohara K
- Journal Title
  
  PLoS One
  
  Volume: 9(3) Issue: 3 Pages: 91373-91373
- DOI
  10.1371/journal.pone.0091373
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590547, KAKENHI-PROJECT-23791093, KAKENHI-PROJECT-24390117, KAKENHI-PROJECT-24658245, KAKENHI-PUBLICLY-25114712, KAKENHI-PROJECT-25461440
[Journal Article] Tupaia belangeri as an experimental animal model for viral infection2014
- Author(s)
  Tsukiyama-Kohara K, Kohara M
- Journal Title
  
  Exp Animal
  
  Volume: accepted
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] Targeted induction of interferon-λ in humanized chimeric mouse liver abrogates hepatotropic virus infection.2013
- Author(s)
  Nakagawa S, Hirata Y, Kameyama T, Tokunaga Y, Nishito Y, Hirabayashi K, Yano J, Ochiya T, Tateno C, Tanaka Y, Mizokami M, Tsukiyama-Kohara K, Inoue K, Yoshiba M, Takaoka A, Kohara M.
- Journal Title
  
  PLoS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] 4E-BP1 regulates the differentiation of white adipose tissue2013
- Author(s)
  Tsukiyama-Kohara K, Katsume A, Kimura K, Saito M, Kohara M
- Journal Title
  
  Genes Cells
  
  Volume: 18(7) Issue: 7 Pages: 602-607
- DOI
  10.1111/gtc.12059
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] Genomic polymorphisms in 3β-hydroxysterol Δ24-reductase promoter sequences.2013
- Author(s)
  Salem NE, Saito M, Kasama Y, Ozawa M, Kawabata T, Harada S, Suda H, Asonuma K, El-Gohary A, Tsukiyama-Kohara K.
- Journal Title
  
  Microbiolgy and Immunolgy
  
  Volume: 57 Issue: 3 Pages: 179-184
- DOI
  10.1111/1348-0421.12025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547, KAKENHI-PROJECT-24658245
[Journal Article] Targeted induction of interferon-λ in humanized chimeric mouse liver abrogates hepatotropic virus infection2013
- Author(s)
  Nakagawa S, Hirata Y, Kameyama T, Tokunaga Y, Nishito Y, Hirabayashi K, Yano J, Ochiya T, Tateno C, Tanaka Y, Mizokami M, Tsukiyama-Kohara K, Inoue K, Yoshiba M, Takaoka A, Kohara M
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 3 Pages: e59611-e59611
- DOI
  10.1371/journal.pone.0059611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23590547, KAKENHI-PROJECT-23659238, KAKENHI-PROJECT-24390117, KAKENHI-PUBLICLY-25114712, KAKENHI-PUBLICLY-23114511
[Journal Article] A serine palmytoiltransferase inhibitor inhibits hepatitis C virus replication in human hepatocytes2013
- Author(s)
  Katsume A, Tokunaga Y, Hirata Y, Munakata T, Saito M, Hayashi H, Okamoto Y, Kusanagi I, Fujiwara S, Klumpp K, Tsukiyama-Kohara K, El-Gohary A, Sudoh M, Kohara M
- Journal Title
  
  Gastroenterology
  
  Volume: 145(4)(pii : S0016-5085(13)00914-1. 10.1053) Pages: 865-73
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] A serine palmitoyltransferase inhibitor blocks hepatitis C virus replication in human hepatocytes.2013
- Author(s)
  Katsume A, Tokunaga Y, Hirata Y, Munakata T, Saito M, Hayashi H, Okamoto K, Ohmori Y, Kusanagi I, Fujiwara S, Tsukuda T, Aoki Y, Klumpp K, Tsukivama-Kohara K, El-Gohary A, Sudoh M, Kohara M.
- Journal Title
  
  Gastroenterology
  
  Volume: 145(4) Issue: 4 Pages: 865-79
- DOI
  10.1053/j.gastro.2013.06.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03079, KAKENHI-PROJECT-24390117, KAKENHI-PROJECT-24590565, KAKENHI-PUBLICLY-25114712
[Journal Article] A serine palmitoyltransferase inhibitor blocks hepatitis C virus replication in human hepatocytes.2013
- Author(s)
  Katsume A, Tokunaga Y, Hirata Y, Munakata T, Saito M, Hayashi H, Okamoto K, Ohmori Y, Kusanagi I, Fujiwara S, Tsukuda T, Aoki Y, Klumpp K, Tsukiyama-Kohara K, El-Gohary A, Sudoh M, Kohara M.
- Journal Title
  
  Gastroenterology
  
  Volume: 145 Pages: 865-873
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] 4E-BP1 regulates the differentiation of white adipose tissue2013
- Author(s)
  Kyoko Tsukiyama-Kohara, Asao Katsume, Kazuhiro Kimura, Masayuki Saito, and Michinori Kohara
- Journal Title
  
  Genes to Cells
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] 4E-BP1 regulates the differentiation of white adipose tissue.2013
- Author(s)
  Tsukiyama-Kohara K, Katsume A, Kimura K, Saito M, Kohara M.
- Journal Title
  
  Genes Cells.
  
  Volume: 18 Pages: 602-607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] Impairment of interferon regulatoroy factor-3 activation by hepatitis C virus core protein basic amino acid region 1.2012
- Author(s)
  Inoue K, Tsukiyama-Kohara K, Matsuda C, Yoneyama M, Fujita T, Kuge S, Yoshida M, Kohara M
- Journal Title
  
  Bichem Biophys Res Commun
  
  Volume: 428 Issue: 4 Pages: 494-499
- DOI
  10.1016/j.bbrc.2012.10.079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390108, KAKENHI-PROJECT-23590547, KAKENHI-PROJECT-23659238, KAKENHI-PROJECT-24390117, KAKENHI-PLANNED-20112009
[Journal Article] Role of oxidative stress in hepatocarcinogenesis induced by hepatitis C virus.2012
- Author(s)
  Tsukiyama-Kohara, K.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 13 Issue: 11 Pages: 15271-8
- DOI
  10.3390/ijms131115271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] Hepatitis C virus promotes expression of the 3β-hydroxysterol δ24-reductase through Sp1.2012
- Author(s)
  Saito M, Kohara, M, Tsukiyama-Kohara K.
- Journal Title
  
  J Med Virol
  
  Volume: 84 Issue: 5 Pages: 733-746
- DOI
  10.1002/jmv.23250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547, KAKENHI-PROJECT-23659238, KAKENHI-PROJECT-24390117, KAKENHI-PUBLICLY-23114511
[Journal Article] Translocase of outer mitochondrial membrane 70 induces interferon response and is impaired by hepatitis C virus NS3.2012
- Author(s)
  Kasama Y, Saito M, Takano T, Nishimura T, Satoh M, Wang Z, Nagla. E. S., Harada S, Kohara M, Tsukiyama-Kohara K.
- Journal Title
  
  Virus Research
  
  Volume: 163 Issue: 1 Pages: 405-9
- DOI
  10.1016/j.virusres.2011.10.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] Immunization with a recombinant vaccinia virus that encodes nonstructural proteins of the hepatitis C virus suppresses viral protein levels in mouse liver.2012
- Author(s)
  Sekiguchi, S, Kimura K, Chiyo T, Ohtsuki T, Tobita Y, Tokunaga Y, Yasui F, Tsukiyama-Kohara K, Wakita T, Tanaka T, Miyasaka M, Mizuno K, Hayashi Y, Hishima T, Matsushima K and Kohara M.
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 12 Pages: e51656-e51656
- DOI
  10.1371/journal.pone.0051656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547, KAKENHI-PROJECT-23591004, KAKENHI-PROJECT-23659238, KAKENHI-PROJECT-24390117, KAKENHI-PUBLICLY-23114511
[Journal Article] Augmentation of DHCR24 expression by hepatitis C virus infection facilitates viral replication in hepatocytes2011
- Author(s)
  Takano T, Tsukiyama-Kohara K, Hayashi M, Hirata Y, Satoh M, Tateno C, Hayashi Y, Hishima T, Funata N, Sudo M, and Kohara M
- Journal Title
  
  J Hepatology
  
  Volume: 55(3) Issue: 3 Pages: 512-521
- DOI
  10.1016/j.jhep.2010.12.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] Hepatitis C virus-related lymphomagenesis in a mouse model2011
- Author(s)
  Tsukiyama-Kohara K, Sekiguchi S, Kasama Y, Salem NE, Machida K, Kohara M
- Journal Title
  
  ISRN Hemato
  
  Volume: 2011 Pages: 167501-167501
- DOI
  10.5402/2011/167501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] Potential of a recombinant measles virus as expression vector of hepatitis C virus envelope proteins2011
- Author(s)
  Kasama Y, Satoh M, Saito M, Okada S, Kai C, and Tsukiyama-Kohara K
- Journal Title
  
  World J Vaccine
  
  Volume: 1 Issue: 03 Pages: 98-103
- DOI
  10.4236/wjv.2011.13010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] Translocase of outer mitochondrial membrane 70 expression is induced by hepatitis C virus and is related to the apoptotic response2011
- Author(s)
  Takano T, Kohara M, Kasama Y, Nishimura T, Saito M, Kai C and Tsukiyama-Kohara K
- Journal Title
  
  J Med Virol
  
  Volume: 83 Issue: 5 Pages: 801-809
- DOI
  10.1002/jmv.22046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] Selective translation of the measles virus nucleocapsid mRNA by la protein2011
- Author(s)
  Inoue Y, Sato H, Fujita K, Tsukiyama-Kohara K, Yoneda M, Kai C
- Journal Title
  
  F ront Microbiol
  
  Volume: 2 Pages: 173-173
- DOI
  10.3389/fmicb.2011.00173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Journal Article] Monoclonal antibody 2-152a suppresses hepatitis C virus infection thorough betaine/GABA transporter-12011
- Author(s)
  Satoh M, Saito M, Takano T, Kasama Y, Nishimura T, Nishito Y, Hirata Y, Arai M, Sudoh M, Kai C, Kohara M and Tsukiyama-Kohara K
- Journal Title
  
  J Infect Dis
  
  Volume: 204(8) Issue: 8 Pages: 1172-1180
- DOI
  10.1093/infdis/jir501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547
[Patent] 口蹄疫ウイルスIRES発現細胞2017
- Inventor(s)
  小原　恭子
- Industrial Property Rights Holder
  鹿児島大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017-05-31
- Data Source
  KAKENHI-PROJECT-15K14871
[Patent] C型肝炎の予防、治療、又は改善用組成物2012
- Inventor(s)
  小原恭子、松森昭　他
- Industrial Property Rights Holder
  松森昭、化学及血清療法研究所、東京都医学研究機構、熊本大学
- Industrial Property Rights Type
  特許
- Patent Publication Number
  2012-250940
- Filing Date
  2012-12-20
- Data Source
  KAKENHI-PROJECT-23590547
[Patent] C型肝炎の予防、治療又は改善用組成物2011
- Inventor(s)
  小原恭子、松森昭、西村知裕、小原道法
- Industrial Property Rights Holder
  国立大学法人熊本大学、松森昭、(一般財団法人)化学及血清療法研究所、(公財)東京都医学研究機構
- Industrial Property Number
  2011-125440
- Filing Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-23590547
[Patent] C型肝炎の予防、治療又は改善用組成物2011
- Inventor(s)
  小原恭子、松森昭、西村知裕、小原道法
- Industrial Property Rights Holder
  熊本大学、松森昭、化学及血清療法研究所、東京都医学研究機構
- Filing Date
  2011
- Data Source
  KAKENHI-PROJECT-23590547
[Patent] Hepatitis C virus inhibitors
- Inventor(s)
  小原恭子、小原道法他
- Industrial Property Rights Holder
  (一般財団法人)化学及血清療法研究所、(公財) 東京都医学研究機構、国立大学法人熊本大学
- Overseas
- Data Source
  KAKENHI-PROJECT-23590547
[Patent] C型肝炎ウイルス阻害剤
- Inventor(s)
  小原恭子、小原道法他
- Industrial Property Rights Holder
  (一般財団法人)化学及血清療法研究所、(公財) 東京都医学研究機構、国立大学法人熊本大学
- Overseas
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] IRES共通因子PKD1L3、USP31の生体内機能の解析2023
- Author(s)
  宇都宮雅史、小原恭子
- Organizer
  第１６6 回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03164
[Presentation] ツパイCYP2E1の同定と解析2023
- Author(s)
  後迫玄城，村山典恵，小原恭子，山崎浩史，宇野泰広
- Organizer
  第１６6 回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03164
[Presentation] Suppression of dengue virus replication by the French maritime pine extract Pycnogenol2023
- Author(s)
  Kazi Anowar Hossain1, Rupaly Akhter, Md Haroon Or Rashid, Lipi Akter, Masashi Utsunomiya, Bouchra Kitab, NgweTun MM, Michinori Kohara, Kouichi Morita, Kyoko Tsukiyama-Kohara
- Organizer
  第１６6 回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03164
[Presentation] Subtype distribution and expression of the koala retrovirus in koala from the Japanese zoo2022
- Author(s)
  Md Abul Hashem, Mohammad Enamul Hoque Kayesh, Kyoko Tsukiyama-Kohara
- Organizer
  第１６５回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03164
[Presentation] ツパイCYP2A13 の同定と解析2022
- Author(s)
  後迫玄城，村山典恵，小原恭子，山崎浩史，宇野泰広
- Organizer
  第１６５回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03164
[Presentation] Characterization of host factors associated with the internal ribosomal entry sites of foot-and-mouth disease and classical swine fever viruses2022
- Author(s)
  Yutaro Ide, Bouchra Kitab, Nobumasa Ito, Riai Okamoto, Yui Tamura, Takafumi Matsui, Yoshihiro Sakoda, and Kyoko Tsukiyama-Kohara
- Organizer
  IUMS2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Presentation] 口蹄疫ウイルスおよび豚熱ウイルスRNAのIRES機能に関連する宿主因子の特性について2022
- Author(s)
  井手優太郎、Bouchra Kitab, 迫田義博、小原恭子
- Organizer
  第１６５回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03164
[Presentation] Expression Profile Of Toll-like Receptors In Koala (Phascolarctos Cinereus) Peripheral Blood Mononuclear Cells Infected With Multiple Korv Subtypes2021
- Author(s)
  Mohammad Enamul Hoque Kayesh, Md Abul Hashem and Kyoko Tsukiyama-Kohara
- Organizer
  WSV 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Presentation] 口蹄疫ウイルスおよび豚熱ウイルスのIRESの機能に関与する共通宿主因子の探索2021
- Author(s)
  井手優太郎、伊藤伸将、田村優依、松井孝文、Bouchra Kitab,小原恭子
- Organizer
  第164回日本獣医学会
- Data Source
  KAKENHI-PROJECT-20H03164
[Presentation] Epidemiological study of KoRV Genotypes in koala in Japanese zoo2021
- Author(s)
  Md Abul Hashem, Mohammad Enamul Hoque Kayesh, Osamu Yamato, Fumie Maetani, Taiki Eiei, Kyoya Mochizuki, Hiroko Sakurai, Ayaka Ito, Hiroki Kannno, Tatsuya Kasahara, Yusuke Amano, and Kyoko Tsukiyama-Kohara
- Organizer
  KoRV symposium 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Presentation] Koala retrovirus (KoRV) subtypes and their impact on captive koala (Phascolarctos cinereus) health2021
- Author(s)
  Md Abul Hashem, Mohammad Enamul Hoque Kayesh, Fumie Maetani5, Hiroko Sakurai, Takayuki Asai and Kyoko Tsukiyama-Kohara
- Organizer
  第164回日本獣医学会
- Data Source
  KAKENHI-PROJECT-20H03164
[Presentation] Transmission Of Koala Retrovirus From Parent Koalas To A Joey In A Japanese Zoo2021
- Author(s)
  Md Abul Hashem1, Mohammad Enamul Hoque Kayesh, Fumie Maetani and Kyoko Tsukiyama-Kohara
- Organizer
  WSV2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03164
[Presentation] TRANSMISSION OF KOALA RETROVIRUS FROM PARENT KOALAS TO A JOEY IN A JAPANESE ZOO2020
- Author(s)
  Md Abul Hashem, Mohammad Enamul Hoque Kayesh, Fumie Maetani, Kyoko Tsukiyama-Kohara
- Organizer
  第163回　日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03164
[Presentation] CSFVのIRES発現細胞の作成と応用2020
- Author(s)
  伊藤伸将, Graham J Belsham, 迫田義博、小原恭子
- Organizer
  第163回　日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03164
[Presentation] Tumorigenicity inducued by hepatitis C virus.2014
- Author(s)
  Tsukiyama-Kohara K., Kohara M. Tumorigenicity inducued by hepatitis C virus.
- Organizer
  第4回新学術領域発がんスパイラル国際シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2014-02-11
- Invited
- Data Source
  KAKENHI-PROJECT-13F03079
[Presentation] Tumorigenicity induced by hepatitis C virus2014
- Author(s)
  Tukiyama-Kohara K, Kohara M
- Organizer
  第4回新学術領域発がんスパイラル国際シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2014-02-11
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Tumorigenicity inducued by hepatitis C virus.2014
- Author(s)
  Tsukiyama-Kohara K., Kohara M
- Organizer
  第4回新学術領域　発がんスパイラル国際シンポジウム
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] 宿主因子阻害剤NA８０８と直接的複製阻害剤の併用による抗HCV活性2013
- Author(s)
  徳永優子、平田雄一、小原恭子、小原道法
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Inflammation and cancer in hepatitis C virus infection2013
- Author(s)
  Tsukiyama-Kohara K, Kimuara K, Kohara M
- Organizer
  3rd IGAKUKEN International Symposium on Control of Influenza and Hepatitis
- Place of Presentation
  Tokyo
- Year and Date
  2013-02-15
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Development of tupaia nelangeri for small animal infection model of hepatitis B virus, according to the genomid research2013
- Author(s)
  Tsukiyama-Kohara, K, Hirata, V., Sanada T, Yamamoto N., Yasui F. Kohara. M
- Organizer
  HBV2013
- Place of Presentation
  上海、中国
- Data Source
  KAKENHI-PROJECT-13F03079
[Presentation] Efficacy of French maritime pine bark extract pycnogenolR to hepatitis C virus replication.2013
- Author(s)
  EZZIKOURI S, Nishimura T, Ozawa M, Kohara M and Tsukiyama-Kohara K.
- Organizer
  第50回ウイルス学会九州支部会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Efficacy of French maritime pine bark extract pycnogenolR to hepatitis C virus replication.2013
- Author(s)
  EZZIKOURI S, Nishimura T, Ozawa M, Kohara M and Tsukiyama-Kohara K.
- Organizer
  ウイルス学会九州支部会
- Place of Presentation
  長崎
- Year and Date
  2013-09-07
- Data Source
  KAKENHI-PROJECT-13F03079
[Presentation] C型肝炎ウイルス誘導性酸化ストレスによる肝細胞腫瘍原性亢進2013
- Author(s)
  小原恭子
- Organizer
  第24回日本生体防御学会
- Place of Presentation
  熊本
- Year and Date
  2013-07-12
- Invited
- Data Source
  KAKENHI-PROJECT-13F03079
[Presentation] Chronic hepatitis C virus model in Tupaia belangeri2013
- Author(s)
  Tsukiyama-Kohara K, Amako Y, Kohara M.
- Organizer
  Symposium HCV Animal models and vaccine development
- Place of Presentation
  Estonia
- Invited
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] 型肝炎ウイルス誘導性酸化ストレスによる肝細胞腫瘍原性更新2013
- Author(s)
  小原恭子
- Organizer
  第24回日本生体防御学会
- Place of Presentation
  熊本
- Year and Date
  2013-07-12
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] C型肝炎ウイルス誘導性酸化ストレスによる肝細胞腫瘍原性亢進2013
- Author(s)
  小原　恭子
- Organizer
  第24回日本生体防御学会
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] C型肝炎誘発性リンパ腫発症モデルマウスの網羅的解析2013
- Author(s)
  笠間由里、小原道法、小原恭子
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Chronic hepatitis C virus model in Tupaia belangeri2013
- Author(s)
  Tsukiyama-Kohara K, Amako Y, Kohara M
- Organizer
  SIMPOSIUM"HCV animal models and vaccine development"
- Place of Presentation
  Tallinn, Estonia
- Year and Date
  2013-05-17
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Development of Tupaia belangeri for small animal infection model of hepatitis B virus, according to the genomic research2013
- Author(s)
  Tsukiyama-Kohara, K, Hirata, Y., Sanada T, Yamamoto N., Sayeh, E., Yasui F, Kohara, M.
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2013-12-03
- Data Source
  KAKENHI-PROJECT-13F03079
[Presentation] C型肝炎ウイルスのBリンパ腫発症要因の解明2013
- Author(s)
  笠間由里、小原道法、小原恭子,
- Organizer
  第50回日本ウイルス学会九州支部会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Development of tupaia nelangeri for small animal infection model of hepatitis B virus, according to the genome research,2013
- Author(s)
  Tsukiyama-Kohara, K, Hirata, Y.,Sanada T, Yamamoto N., Yasui F, Kohara, M,
- Organizer
  HBV2013
- Place of Presentation
  上海(中国）
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Critical factors in HCV related B-cell lymphoma development characterized by comprehensive analysis of B-lymphoma cells in the HCV transgenic mice2013
- Author(s)
  Tsukiyama-Kohara, K, Kasama, Y, Kohara, M
- Organizer
  20th HCV Symposium
- Place of Presentation
  オーストラリア
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] ツパイとヒトとの遺伝的相同性の検証2013
- Author(s)
  金澤伯弘、川畑淑子、永野希織、小原道法、小澤真、小原恭子.
- Organizer
  日本獣医学会学術集会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Chronic hepatitis C virus model in Tupaia belangeri2013
- Author(s)
  Tsukiyama-Kohara K. Amako Y Kohara M.
- Organizer
  Symposium HCV Animal models and vaccine d evelopment
- Place of Presentation
  Estonia
- Year and Date
  2013-05-17
- Invited
- Data Source
  KAKENHI-PROJECT-13F03079
[Presentation] Inflammation and Cancer in Hepatitis C virus Infection2012
- Author(s)
  Tsukiyama-Kohara K, Kimuara K, Kohara M
- Organizer
  International symposium : Infection, immunity and cancer
- Place of Presentation
  Kyoto
- Year and Date
  2012-01-17
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Inflammation and Cancer in Hepatitis C virus Infection2012
- Author(s)
  Kyoko Kohara, Kiminori Kimura, Michinori Kohara
- Organizer
  International symposium: Infection, immunity and cancer(招待講演)
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Antibody against 3β-Hydroxysterol-Δ24-Reductase Suppresses Hepatitis C Virus Infection through Betaine/GABA Transporter-12012
- Author(s)
  Satoh, M., Kohara, M., Tsukiyama-Kohara, K.
- Organizer
  HCV2012
- Place of Presentation
  Venice
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Persistent expression of the full genome of hepatitis C virus in B cells induces spontaneous development of B-cell lymphomas in vivo.2012
- Author(s)
  K. Tsukiyama-Kohara, M. Kohara.
- Organizer
  第11回あわじしま感染症;免疫フォーラム
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] C型肝炎ウイルスのBリンパ腫発症要因解明に向けた研究.2012
- Author(s)
  小原恭子、笠間由里、小原道法.
- Organizer
  第６０回日本ウイルス学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Elevation of apoptosis induced by mutant DHCR24 with potential MDM2 binding motif in hepatocytes.2012
- Author(s)
  Qi, X, Harada, S., Tsukiyama-Kohara, K.
- Organizer
  第６０回日本ウイルス学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Augmentation of DHCR24 expression by hepatitis C virus infection facilitates viral replication in hepatocytes.2012
- Author(s)
  Takashi Takano, Kyoko Tsukiyama-Kohara, Michinori Kohara.
- Organizer
  Congress of European Association for the Study of the Liver (EASL2012).
- Place of Presentation
  Barcellona
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Modification of translocase of outer mitochondrial membrane 70 by hepatitis C virus in apoptotic response and interferon induction.2012
- Author(s)
  Takano, T., Kasama, Y., Kohara, M., Tsukiyama-Kohara, K.
- Organizer
  第３５回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] C型肝炎ウイルスの複製に関与する新規宿主因子BGT-1.2012
- Author(s)
  佐藤正明、齊藤誠、小原道法、小原恭子
- Organizer
  第７１回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Role of DHCR24 in hepatitis C virus replication in hepatocytes.2011
- Author(s)
  Takano K, Kohara M, and Tsukiyama-Kohara K.
- Organizer
  第７０回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Exploitation of molecular targeting therapy for hepatitis C virus-related hepatocellular carcinoma forcusing on DHCR24.2011
- Author(s)
  Saito M, Tsukiyama-Kohara K.
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] 新規C型肝癌マーカーDHCR24を利用した分子標的治療の開発2011
- Author(s)
  齊藤誠、小原恭子
- Organizer
  第48回日本ウイルス学会九州支部会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Overexpression of 3beta-Hydroxysterol delta24Reductase is induced by hepatitis C virus infection through oxidative stress mediated Sp1 activation.2011
- Author(s)
  Saito M, Kohara M, and Tsukiyama-Kohara K.
- Organizer
  International Union of Microbiological Societies
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Spontaneous development of B-cell lymphomas by persistent expression of the full genome of hepatitis C virus in B cells in mice.2011
- Author(s)
  Tsukiyama-Kohara K, Kasama Y and Kohara M.
- Organizer
  "Recent Advances in pathogenic human viruses" in 2011 ASBMB Special symposia series.
- Place of Presentation
  Guanzhou, China
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Augmentation of DHCR24 expression by hepatitis C virus infection facilitates viral replication in hepatocytes.2011
- Author(s)
  Takano T, Tsukiyama-Kohara K, Hirata Y, Tokunaga Y, Tateno C, Sudoh M, and Kohara M.
- Organizer
  The 18th international meeting on Hepatitis C virus and related viruses
- Place of Presentation
  Seatle, USA
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Hepatitis C virus induces translocase of outer mitochondria membrane 70 which regulates apoptotic response.2011
- Author(s)
  Takano T, Kasama Y, Kohara M, and Tsukiyama-Kohara K.
- Organizer
  The 18th international meeting on Hepatitis C virus and related viruses
- Place of Presentation
  Seatle, USA
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] French marine bark extract pycnogenol is a new candidate of Hepatitis C virus therapeutic material.2011
- Author(s)
  Nishimura T，Kohara M，Kino Y，Tsukiyama-Kohara K.
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] C型肝炎ウイルス誘発性リンパ腫発症モデルマウスの樹立と解析2011
- Author(s)
  笠間　由里、関口敏、齊藤誠、佐藤正明、桑原一彦、阪口薫雄、竹屋元裕、日浅陽一、小原道法、小原恭子
- Organizer
  第７回麒麟塾(招待講演)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Recombinant vaccinia virus encoding hepatitis C virus nonstructuralprotein cures chronic hepatitis in mouse model.2011
- Author(s)
  Kohara M, Kimura K, Tsukiyama-Kohara K.
- Organizer
  第７０回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Persistent expression of the full genome of hepatitis C virus in B cells induces spontaneous development of B-cell lymphomas in vivo.2011
- Author(s)
  Kasama Y, Sekiguchi S, Saito M, Satoh M, Kuwahara K, Takeya M, Sakaguchi N, Kohara M, Tsukiyama-Kohara K.
- Organizer
  International Union of Microbiological Societies
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Application of DHCR24 for the diagnosis of hepatocellular carcinoma (HCC).2011
- Author(s)
  Nagla ES, Nishimura T, Saito M, Kohara M, Harada S, El-Gohary A, and Tsukiyama-Kohara K.
- Organizer
  International Union of Microbiological Societies
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Persistent expression of the full genome of hepatitis C virus in B cells induces spontaneous development of B-cell lymphomas in mice.2011
- Author(s)
  Kasama Y, Sekiguchi S, and Kohara M, Tsukiyama-Kohara K
- Organizer
  The 18th international meeting on Hepatitis C virus and related viruses
- Place of Presentation
  Seatle, USA
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Molecular target therapy for hepatitic C virus-related hepatocellular carcinoma with cell-surface expression of DHCR242011
- Author(s)
  Saito M, Tsukiyama-Kohara K
- Organizer
  第７０回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Persistent infection of Hepatitis C Virus2007
- Author(s)
  Kohara M
- Organizer
  第7回あわじしま感染症・免疫フォーラム
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-18012052
[Presentation] 宿主因子を標的にしたC型肝炎ウイルス複製の制御2007
- Author(s)
  小原道法
- Organizer
  第21回臨床肝臓カンファレンス
- Place of Presentation
  東京
- Year and Date
  2007-06-30
- Data Source
  KAKENHI-PROJECT-18012052
[Presentation] スフィンゴ脂質とC型肝炎ウイルス複製2007
- Author(s)
  小原道法
- Organizer
  第49回日本脂質生化学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18012052
[Presentation] HBV pathogenesis and host response in Tupaia belangeri
- Author(s)
  Sanada T, Yamamoto N, Tsukiyama-Kohara K, Ezzikouri S, Tateno C, Kohara M
- Organizer
  2014 HBV international Meeting
- Place of Presentation
  UCLA, ロサンジェルス、アメリカ
- Year and Date
  2014-09-03 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-13F03079
[Presentation] Inhibitory Effects of Pycnogenol on Hepatitis C Virus Replication.
- Author(s)
  Ezzikouri S., Kohara M, Tsukiyama-Kohara K.
- Organizer
  第73回日本癌学会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-13F03079
[Presentation] Comprehensive analysis of B-lymphoma cells spontaneously developed in transgenic mice that express the full hepatitis C virus genome in B cells
- Author(s)
  Tsukiyama-Kohara K, Kohara M, and Kasama Y
- Organizer
  第16回国際ウイルス学会(ICV2014)
- Place of Presentation
  バンフ、カナダ
- Year and Date
  2014-07-27 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-13F03079
[Presentation] A comprehensive study of B-lymphoma cells spontaneously developed in transgenic mice that express the full hepatitis C virus genome in B cells.
- Author(s)
  Tsukiyama-Kohara K and Kohara M.
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-13F03079
[Presentation] Inflammation and cancer in hepatitis C virus infection.
- Author(s)
  Tsukiyama-Kohara, K., Kimura, K., Kohara, M.
- Organizer
  3rd_IGAKUKEN International Symposium on Control of Influenza and Hepatitis
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23590547
[Presentation] Development of Tupaia belangeri for HBV persistent infection.
- Author(s)
  Ezzikouri, S., Chi, H.Y.., Sanada, T., Nagano, K., Yamaguchi, C.., Kanda, T., Kanazawa, N., Okuya, K., Ueno, K., Nakagawa, H., Nkogue, C.N., Ozawa, M., Miyoshi, N., Benjelloun, S., Murakami, S., Tanaka, Y., Kohara, M., Tsukiyama-Kohara, K.
- Organizer
  第62回日本ウイルス学会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-13F03079
[Presentation] Palmitoyltransferase Inhibitor Inhibits Hepatitis C Virus Replication in Human Hepatocytes.
- Author(s)
  Kohara M, Tokunaga Y, Tsukiyama-Kohara K, Sudoh M.
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-13F03079

1. KAI Chieko (10167330)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. KOHARA Michinori (10250218)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
3. MIURA Ryuichi (00322074)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. TSUJIMOTO Hajime (60163804)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. YONEKAWA Hiromichi (30142110)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NAKAYAMA Hiroyuki (40155891)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. ENDO Yasuyuki (90332600)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. EZZIKOURI Sayeh

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
9. WAKITA Takaji (40280789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. FUJITA Takasi (10156870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TOYODA Tetsuya (00197972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YAMANOUCHI Kazuya (30072888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 高野貴士 (20462781)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 塗谷秀子 (80270685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 習田昌裕 (10356256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 高橋英司 (50183439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 上田進 (00072463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 加藤篤 (40152699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 岡林環樹 (10359995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 迫田義博 (40333637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
21. 藤田志歩 (90416272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. 安田二朗 (10282518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 井上英治 (70527895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TSUCHIYA Masayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. OZAWA Makoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. ITO Kiyoaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 米山光俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 松鵜彩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 宇野泰広

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
30. 山崎浩史

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
31. 溝上雅史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 高松由基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 山極壽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kohara Kyoko 小原 恭子

KOHARA Kyoko 小原 恭子

小原 恭子 コハラ キョウコ

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Basic study for identification of common FMDV, CSFV IRES factors and its applicationPrincipal Investigator

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Foot and mouth disease virus specific translation inhibition and application for development of disease resistant livestockPrincipal Investigator

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ツパイゲノム情報に基づく肝炎ウイルス動物感染系の確立に関する研究Principal Investigator

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Impact of hepatitis C virus infection in B cells on pathogenesisPrincipal Investigator

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新組み換え技術を用いたがん治療用麻疹ウイルスベクターの開発Principal Investigator

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Development of the new vaccine and a delivery vector by the recombination Morbilli virus.Principal Investigator

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C型肝炎ウイルスのツパイ感染実験モデル系の開発Principal Investigator

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Kohara Kyoko 小原恭子

KOHARA Kyoko 小原恭子

小原恭子コハラキョウコ

[Book] 生命科学のためのウイルス学（監訳　下遠野邦忠、瀨谷司）2015