OGASAWARA YUKI 小笠原裕樹

… Alternative Names

小笠原裕樹オガサワラユウキ

OGASAWARA Yuki 小笠原裕樹

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Researcher Number	20231219
Other IDs
Affiliation (Current)	2025: 明治薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2025: 明治薬科大学, 薬学部, 教授 2016 – 2023: 明治薬科大学, 薬学部, 教授 2013 – 2014: 明治薬科大学, 薬学部, 教授 2010 – 2012: 明治薬科大学, 薬学部, 准教授 2009: Meiji Pharmaceutical University, 薬学部, 講師 1999: 明薬大, 薬学部, 助手 1998: 明治薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Hygiene / Medical pharmacy / Environmental pharmacy Except Principal Investigator Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator メチルグリオキサール / カルボニルストレス / 統合失調症 / 糖化 / 翻訳後修飾 / methylglyoxal / glycation / カルボニル化タンパク質 / carbonyl stress / 治療抵抗性統合失調症 … More / DNA損傷 / 胸膜中皮細胞 / 酸化ストレス / カーボンナノチューブ / 糖化タンパク質 / 神経変性疾患 / カルボニル化合物消去剤 / プロテオミクス / 海馬 / クレチンキナーゼ / MG-H1 / モデルマウス / 診断マーカー / carnosic acid / persulfide / polysulfide / glutathione / Nrf2 pathway / argpyrimidine / schizophrenia / 治療抵抗性 / バイオマーカー / ナノマテリアル / 抗酸化酵素 / 酸化ストレスマーカー / 遷移金属 / 暴露指標 / 修復酵素 / 脂質過酸化 / 中皮種細胞 / 多層カーボンナノチューブ / アスベスト / カルボニル化 / 肺胞上皮細胞 / 中皮細胞 / 細胞増殖阻害 / 遺伝毒性 / コメットアッセイ / DNA損傷修復 / ロダネーゼ / 解毒 / イオウ転移酵素 / シアン … More Except Principal Investigator 肺 / 酸化ストレス / マクロファージ / 健康影響 / バイオイメージング / 微小循環 / 肺胞マクロファージ / 動物実験 / 生体影響 / 加熱式たばこ Less

神経変性疾患の原因となる蛋白質のカルボニル化による凝集の促進と抑制に関する研究Principal Investigator
- Principal Investigator
  
  小笠原裕樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Meiji Pharmaceutical University
疾患モデル動物を用いたカルボニルストレス性統合失調症の発症機序と治療に関する研究Principal Investigator
- Principal Investigator
  
  小笠原裕樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Meiji Pharmaceutical University
Study of pathogenic mechanism in treatment-resistant schizophrenia involved in glycative stressPrincipal Investigator
- Principal Investigator
  
  Ogasawara Yuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Meiji Pharmaceutical University
A Study on the Health Effects of Heated Tobacco Products Measured by Changes in Pulmonary Microcirculation and Alveolar Macrophage Behavior
- Principal Investigator
  
  Ushiyama Akira
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  National Institute of Public Health
Study of biomarker as a mediator for appropriate diagnosis and medication for schizophreniaPrincipal Investigator
- Principal Investigator
  
  OGASAWARA YUKI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Meiji Pharmaceutical University
Analysis of DNA damage induced by exposure of carbon nanotubes in mesotherial cellsPrincipal Investigator
- Principal Investigator
  
  OGASAWARA Yuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Meiji Pharmaceutical University
DNA damage in human pleural mesothelial cells and lung epithelial cells induced by exposure to carbon nanotubesPrincipal Investigator
- Principal Investigator
  
  OGASAWARA Yuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Meiji Pharmaceutical University
シアンによるイオウ転移酵素の発現誘導と解毒機序の解明Principal Investigator
- Principal Investigator
  
  小笠原裕樹
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Meiji Pharmaceutical University

[Journal Article] Analysis and characterization of sulfane sulfur2024
- Author(s)
  Koike Shin, Ogasawara Yuki
- Journal Title
  
  Analytical Biochemistry
  
  Volume: 687 Pages: 115458-115458
- DOI
  10.1016/j.ab.2024.115458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06780
[Journal Article] Novel Fluorometric Assay of Antiglycation Activity Based on Methylglyoxal-Induced Protein Carbonylation2023
- Author(s)
  Koike Shin, Saito Yuna, Ogasawara Yuki
- Journal Title
  
  Antioxidants
  
  Volume: 12 Issue: 12 Pages: 2030-2030
- DOI
  10.3390/antiox12122030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06780, KAKENHI-PROJECT-21K06652
[Journal Article] Exposure to aerosol extract from heated tobacco products causes a drastic decrease of glutathione and protein carbonylation in human lung epithelial cells2022
- Author(s)
  Nishimoto-Kusunose S.、Sawa M.、Inaba Y.、Ushiyama A.、Ishii K.、Hattori K.、Ogasawara Y.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 589 Pages: 92-99
- DOI
  10.1016/j.bbrc.2021.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04041
[Journal Article] Accumulation of Carbonyl Proteins in the Brain of Mouse Model for Methylglyoxal Detoxification Deficits2021
- Author(s)
  Koike Shin、Toriumi Kazuya、Kasahara Sakura、Kibune Yosuke、Ishida Yo-ichi、Dan Takashi、Miyata Toshio、Arai Makoto、Ogasawara Yuki
- Journal Title
  
  Antioxidants
  
  Volume: 10 Issue: 4 Pages: 574-574
- DOI
  10.3390/antiox10040574
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04887, KAKENHI-PROJECT-18K06977, KAKENHI-PROJECT-19K07208, KAKENHI-PROJECT-21K06652
[Journal Article] A Newly Developed Aerosol Exposure Apparatus for Heated Tobacco Products for In Vivo Experiments Can Deliver Both Particles and Gas Phase With High Recovery and Depicts the Time-Dependent Variation in Nicotine Metabolites in Mouse Urine2021
- Author(s)
  Sawa Marie、Ushiyama Akira、Inaba Yohei、Uchiyama Shigehisa、Hattori Kenji、Ogasawara Yuki、Ishii Kazuyuki
- Journal Title
  
  Nicotine & Tobacco Research
  
  Volume: 23 Issue: 12 Pages: 2145-2152
- DOI
  10.1093/ntr/ntab123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04041
[Journal Article] Oxidative Formation of Methylglyoxal in Glycerol Preparations during Storage2020
- Author(s)
  Sugiura K, Koike S, Suzuki T, Ogasawara Y.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 5 Pages: 879-883
- DOI
  10.1248/bpb.b19-01120
- NAID
  130007839310
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-05-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07208, KAKENHI-PROJECT-19K16425
[Journal Article] Troglitazone Impedes the Oligomerization of Sodium Taurocholate Cotransporting Polypeptide and Entry of Hepatitis B Virus Into Hepatocytes2019
- Author(s)
  Fukano Kento、Tsukuda Senko、Oshima Mizuki、Suzuki Ryosuke、Aizaki Hideki、Ohki Mio、Park Sam-Yong、Muramatsu Masamichi、Wakita Takaji、Sureau Camille、Ogasawara Yuki、Watashi Koichi
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 9 Pages: 3257-3257
- DOI
  10.3389/fmicb.2018.03257
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-16K08383, KAKENHI-PROJECT-16K19145, KAKENHI-PROJECT-17H04085
[Journal Article] Age-related alteration in the distribution of methylglyoxal and its metabolic enzymes in the mouse brain2019
- Author(s)
  Koike S, Ando C, Usui Y, Kibune Y, Nishimoto S, Suzuki T, Ogasawara Y.
- Journal Title
  
  Brain Research Bulletin
  
  Volume: 144 Pages: 164-170
- DOI
  10.1016/j.brainresbull.2018.11.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08383, KAKENHI-PROJECT-17K15525, KAKENHI-PROJECT-19K07208
[Journal Article] Differential oxidation processes of peroxiredoxin 2 dependent on the reaction with several peroxides in human red blood cells2019
- Author(s)
  Ishida YI, Ichinowatari Y, Nishimoto S, Koike S, Ishii K, Ogasawara Y
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 518 Issue: 4 Pages: 615-619
- DOI
  10.1016/j.bbrc.2019.08.108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07208
[Journal Article] Alternative pathway of H2S and polysilfides production form reaction intermediate of 3-mercaptopyruvate sulfurtransferase2018
- Author(s)
  Nagahara N, Koike S, Nirasawa T ,Kimura H, Ogasawara Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 496 Issue: 2 Pages: 648-653
- DOI
  10.1016/j.bbrc.2018.01.056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08322, KAKENHI-PROJECT-26460115, KAKENHI-PROJECT-26460352, KAKENHI-PROJECT-17K08331, KAKENHI-PROJECT-17K08613, KAKENHI-PROJECT-16K08383
[Journal Article] Cysteine persulfides and polysulfides produced by exchange reactions with H2S protect SH-SY5Y cells from methylglyoxal-induced toxicity through Nrf2 activation.2017
- Author(s)
  Koike S, Nishimoto S, Ogasawara Y.
- Journal Title
  
  Redox Biol.
  
  Volume: 12 Pages: 530-539
- DOI
  10.1016/j.redox.2017.03.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08383, KAKENHI-PROJECT-17K15525
[Journal Article] Identification of an argpyrimidine-modified protein in human red blood cells from schizophrenic patients: A possible biomarker for diseases involving carbonyl stress.2017
- Author(s)
  Ishida YI, Kayama T, Kibune Y, Nishimoto S, Koike S, Suzuki T, Horiuchi Y, Miyashita M, Itokawa M, Arai M, Ogasawara Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 493 Pages: 573-577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08383
[Journal Article] Activation of Nrf2 attenuates carbonyl stress induced by methylglyoxal in human neuroblastoma cells: Increase in GSH levels is a critical event for the detoxification mechanism.2017
- Author(s)
  Nishimoto S, Koike S, Inoue N, Suzuki T, Ogasawara Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 483 Issue: 2 Pages: 874-879
- DOI
  10.1016/j.bbrc.2017.01.024
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08383
[Journal Article] Determination of methylglyoxal in human blood plasma using fluorescence high performance liquid chromatography after derivatization with 1,2-diamino-4,5-methylenedioxybenzene.2016
- Author(s)
  Ogasawara Y, Tanaka R, Koike S, Horiuchi Y, Miyashita M, Arai M.
- Journal Title
  
  J Chromatogr B Analyt Technol Biomed Life Sci.
  
  Volume: 1029-1030 Pages: 102-5
- DOI
  10.1016/j.jchromb.2016.07.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05380, KAKENHI-PROJECT-15K14973, KAKENHI-PROJECT-16K08383
[Journal Article] Polysulfides protect SH-SY5Y cells from methylglyoxal-induced toxicity by suppressing protein carbonylation: A possible physiological scavenger for carbonyl stress in the brain.2016
- Author(s)
  Koike S, Kayama T, Yamamoto S, Komine D, Tanaka R, Nishimoto S, Suzuki T, Kishida A, Ogasawara Y.
- Journal Title
  
  Neurotoxicology
  
  Volume: 55 Pages: 13-19
- DOI
  10.1016/j.neuro.2016.05.003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08383
[Journal Article] Irreversible hyperoxidation of peroxiredoxin 2 is caused by tert-butyl hydroperoxide in human red blood cells.2014
- Author(s)
  Ishida YI, Takikawa M, Suzuki T, Nagahama M, Ogasawara Y
- Journal Title
  
  FEBS Open Bio.
  
  Volume: 4 Issue: 1 Pages: 848-852
- DOI
  10.1016/j.fob.2014.10.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590766
[Journal Article] ヒト胸膜中皮由来細胞に対するカーボンナノチューブ曝露によるDNA損傷作用2012
- Author(s)
  小笠原裕樹、梅津憲章、石井一行
- Journal Title
  
  衛生学雑誌
  
  Volume: 67巻 Pages: 76-83
- NAID
  10030212285
- URL
  http://dx.doi.org/10.1265/jjh.67.76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590670
[Journal Article] ヒト胸膜中皮由来細胞に対するカーボンナノチューブ曝露によるDNA損傷作用2012
- Author(s)
  小笠原裕樹、梅津　石井一行
- Journal Title
  
  日本衛生学雑誌
  
  Volume: 67
- NAID
  10030212285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590766
[Journal Article] ヒト胸膜中皮由来細胞に対するカーボンナノチューブ曝露によるDNA損傷作用2012
- Author(s)
  小笠原裕樹、梅津憲章、石井一行
- Journal Title
  
  日本衛生学雑誌
  
  Volume: 67 Pages: 76-83
- NAID
  10030212285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590670
[Journal Article] UVB照射によるマウス皮膚微笑血管床における急性炎症反応に関する研究2010
- Author(s)
  中込哲、牛山明、高橋美雪、小笠原裕樹、石井一行、浅野牧茂、大久保千代治
- Journal Title
  
  生体医工学
  
  Volume: 48 Pages: 42-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590670
[Journal Article] Disruption of glutathione homeostasis causes accumulation of S-glutathionyl proteins response to exposure to reactive oxygen species in human erythrocytes2010
- Author(s)
  Ogasawara Y, Komiyama M, Funakoshi M, Ishii K.
- Journal Title
  
  Biol.Pharm.Bull.
  
  Volume: 33 Pages: 1925-1931
- NAID
  130000402320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590670
[Journal Article] Exposure to chrysotile asbestos causes carbonylation of glucose 6-phosphate dehydrogenase through a reaction with lipid peroxidation products in human lung epithelial cells2010
- Author(s)
  Ogasawara Y, Ishii K.
- Journal Title
  
  Toxicol.Lett.
  
  Volume: 195 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590670
[Journal Article] Exposure to chrysotile asbestos causes carbonylation of glucose 6-phosphate dehydrogenase through a reaction with lipid peroxidation products in human lung epithelial cells2010
- Author(s)
  Ogasawara Y, Ishii K.
- Journal Title
  
  Toxicol.Lett. 195(Epub Mar 6)
  
  Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590670
[Journal Article] Exposure to chrysotile asbestos causes carbonylation of glucose 6-phosphate dehydrogenase through a reaction with lipid peroxidation products in human lung epithelial cells2010
- Author(s)
  Ogasawara Y, Ishii K.
- Volume
  195
- Pages
  1-8
- URL
  http://dx.doi.org/10.1016/j.toxlet.2010.03.001
- Data Source
  KAKENHI-PROJECT-21590670
[Journal Article] Determination of Reduced Nicotinamide Adenine Dinucleotide Phosphate Concentration using High-performance Liquid Chromatography with Fluorescence Detection : Ratio of the Reduced Form as a Biomarker of Oxidative Stress2009
- Author(s)
  Ogasawara Y, Funakoshi M, Ishii K.
- Journal Title
  
  Biol.Pharm.Bull. 32
  
  Pages: 1819-1823
- NAID
  130000116950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590670
[Journal Article] 3-Mercaptopyruvate Sulfurtransferase Produces Hydrogen Sulfide and Bound Sulfane Sulfur in the Brain2009
- Author(s)
  Shibuya N, Tanaka M, Yoshida M, Ogasawara Y, Togawa T, Ishii K, Kimura H.
- Journal Title
  
  Antioxid.Redox Signal. 11
  
  Pages: 703-714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590670
[Presentation] Nrf2系の活性化によるメチルグリオキサール誘導性カルボニルストレスの軽減2024
- Author(s)
  鶴留里梨、小池伸、鈴木俊宏、小笠原裕樹
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K06780
[Presentation] カルボニルストレス性統合失調症モデルマウスにおける、脳内カルボニル化タンパク質の解析2021
- Author(s)
  小笠原裕樹
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07208
[Presentation] LC-MS/MSによる胆汁酸同時分析法の開発とマウス脳内胆汁酸の測定2020
- Author(s)
  宮地勇佑、佐野日向子、相川奈月、甲斐雅之、楠瀬翔一、小池伸、鈴木俊宏、小笠原裕樹
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K07208
[Presentation] グリセリン製剤中におけるメチルグリオキサールの生成に関する研究2020
- Author(s)
  杉浦江、小池伸、鈴木俊宏、小笠原裕樹
- Organizer
  第64回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K07208
[Presentation] カルボニルストレス性統合失調症患者由来 iPS細胞の解析2019
- Author(s)
  堀内泰江, 石川充, 小幡菜々子, 畠中真依, 許絲茵, 小池伸, 鳥海和也、宮下光弘、宮岡祐一郎, 小笠原裕樹, 勝田奈那, 永井竜児, 岡野栄之, 糸川昌成, 新井誠
- Organizer
  第29回日本メイラード学会
- Data Source
  KAKENHI-PROJECT-19K07208
[Presentation] 疾患モデルマウスを用いたカルボニルストレス性統合失調症に関する研究2019
- Author(s)
  木船陽介、小池伸、鈴木俊宏、石田洋一、鳥海和也、新井誠、小笠原裕樹
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08383
[Presentation] Glo1遺伝子欠損とビタミン B6欠乏がマウスの精神行動に与える影響2019
- Author(s)
  鳥海和也、鈴木一浩、小池伸、宮下光弘、堀内泰江、吉川茜、小笠原裕樹、糸川昌成、新井誠
- Organizer
  第29回日本メイラード学会
- Data Source
  KAKENHI-PROJECT-19K07208
[Presentation] 疾患モデルマウスの海馬に蓄積するAGEs含有タンパク質の解析2019
- Author(s)
  笠原桜、小池伸、鳥海和也、新井誠、鈴木俊宏、小笠原裕樹
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07208
[Presentation] 疾患モデルマウスを用いたカルボニルストレス性統合失調症に関する研究2019
- Author(s)
  木船陽介、小池伸、鈴木俊宏、石田洋一、鳥海和也、新井誠、小笠原裕樹
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-19K07208
[Presentation] 老齢マウス脳内におけるメチルグリオキサール濃度の測定2018
- Author(s)
  小池伸、安藤千尋、臼井遥祐、小笠原裕樹
- Organizer
  第28回日本臨床精神神経薬理学会
- Data Source
  KAKENHI-PROJECT-16K08383
[Presentation] 統合失調症患者赤血球中のアルグピリミジン化タンパク質の同定2018
- Author(s)
  木船陽介、鹿山将、小池伸、鈴木俊宏、石田洋一、堀内泰江、宮下光弘、新井誠、小笠原裕樹
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K08383
[Presentation] 神経細胞における Nrf2 活性化によるメチルグリオキサール誘導性カルボニルストレスの軽減作用2017
- Author(s)
  西本翔一、小池伸、井上奈帆、鈴木俊宏、小笠原裕樹
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K08383
[Presentation] 8.グリオキサラーゼ1欠損マウス脳内のメチルグリオキサールの測定2017
- Author(s)
  小池伸、西本翔一、川村久美子、鳥海和也、新井誠、小笠原裕樹
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-16K08383
[Presentation] 神経細胞における結合型イオウの抗カルボニルストレス作用の検討2016
- Author(s)
  小池伸、小峰大典、山元繁秀、小笠原裕樹
- Organizer
  第38回日本生物学的精神医学会
- Place of Presentation
  福岡
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-16K08383
[Presentation] ヒト胸膜中皮由来細胞を用いたカーボンナノチューブの毒性評価2014
- Author(s)
  松井　勇太，小笠原　裕樹，服部　研之，石井　一行
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本市総合体育館（熊本）
- Data Source
  KAKENHI-PROJECT-24590766
[Presentation] ナノサイズ酸化チタン暴露による酸化的DNA損傷の評価2013
- Author(s)
  森井　茜、青沼　えり、小笠原　裕樹、野口　拓巳、石井　一行
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜 (横浜)
- Data Source
  KAKENHI-PROJECT-24590766
[Presentation] ナノサイズ酸化チタン曝露による酸化的DNA損傷の評価2012
- Author(s)
  野口拓巳、小笠原裕樹、石井一行
- Organizer
  日本薬学会第132年回
- Place of Presentation
  北海道大学(札幌)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21590670
[Presentation] ナノサイズ酸化チタン曝露による酸化的DNA損傷の評価2012
- Author(s)
  野口拓巳、小笠原裕樹、石井一行
- Organizer
  日本薬学会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-21590670
[Presentation] ヒト胸膜中皮由来細胞を用いたナノ粒子の毒性評価2011
- Author(s)
  梅津憲章、金子孝太、寺澤洋輔、小笠原裕樹、石井一行
- Organizer
  日本薬学会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21590670
[Presentation] ヒト胸膜中皮由来細胞を用いたナノ粒子の毒性評価2011
- Author(s)
  梅津憲章、金子孝太、寺澤洋輔、小笠原裕樹、石井一行
- Organizer
  日本薬学会
- Place of Presentation
  ツインメッセ静岡(静岡県)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21590670
[Presentation] 肺胞上皮細胞及び胸膜中皮細胞を用いたナノ粒子の毒性評価2010
- Author(s)
  梅津憲章, 太田真帆, 菅野準, 小笠原裕樹, 石井一行
- Organizer
  日本薬学会
- Place of Presentation
  桃太郎アリーナ(岡山県)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21590670
[Presentation] 肺胞上皮細胞及び胸膜中皮細胞を用いたナノ粒子の毒性評価2010
- Author(s)
  梅津憲章、太田真帆、菅野準、小笠原裕樹、石井一行
- Organizer
  日本薬学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21590670
[Presentation] ヒト赤血球中還元型および酸化型Peroxiredoxin2の同時分析法の開発
- Author(s)
  瀧川まりあ、船木裕介、小池伸、鈴木俊宏、小笠原裕樹
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590766
[]

1. Ushiyama Akira (60291118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 中舘和彦 (80372895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 稲葉洋平 (80446583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 服部研之 (90306663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. ITOKAWA MASANARI

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. HORIUCHI Yasue

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. MIYASHITA Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 相崎英樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 新井誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 永原則之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OGASAWARA YUKI 小笠原 裕樹

小笠原 裕樹 オガサワラ ユウキ

OGASAWARA Yuki 小笠原 裕樹

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神経変性疾患の原因となる蛋白質のカルボニル化による凝集の促進と抑制に関する研究Principal Investigator

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疾患モデル動物を用いたカルボニルストレス性統合失調症の発症機序と治療に関する研究Principal Investigator

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Study of pathogenic mechanism in treatment-resistant schizophrenia involved in glycative stressPrincipal Investigator

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A Study on the Health Effects of Heated Tobacco Products Measured by Changes in Pulmonary Microcirculation and Alveolar Macrophage Behavior

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Study of biomarker as a mediator for appropriate diagnosis and medication for schizophreniaPrincipal Investigator

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Analysis of DNA damage induced by exposure of carbon nanotubes in mesotherial cellsPrincipal Investigator

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DNA damage in human pleural mesothelial cells and lung epithelial cells induced by exposure to carbon nanotubesPrincipal Investigator

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シアンによるイオウ転移酵素の発現誘導と解毒機序の解明Principal Investigator

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[Journal Article] Analysis and characterization of sulfane sulfur2024

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[Journal Article] Novel Fluorometric Assay of Antiglycation Activity Based on Methylglyoxal-Induced Protein Carbonylation2023

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[Journal Article] Exposure to aerosol extract from heated tobacco products causes a drastic decrease of glutathione and protein carbonylation in human lung epithelial cells2022

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[Journal Article] Accumulation of Carbonyl Proteins in the Brain of Mouse Model for Methylglyoxal Detoxification Deficits2021

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[Journal Article] A Newly Developed Aerosol Exposure Apparatus for Heated Tobacco Products for In Vivo Experiments Can Deliver Both Particles and Gas Phase With High Recovery and Depicts the Time-Dependent Variation in Nicotine Metabolites in Mouse Urine2021

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[Journal Article] Oxidative Formation of Methylglyoxal in Glycerol Preparations during Storage2020

OGASAWARA YUKI 小笠原裕樹

小笠原裕樹オガサワラユウキ

OGASAWARA Yuki 小笠原裕樹