NISHIDA Koyo 西田孝洋

… Alternative Names

西田孝洋ニシダコウヨウ

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Researcher Number	20237704
Other IDs
External Links
Affiliation (Current)	2025: 長崎大学, 医歯薬学総合研究科(薬学系), 教授
Affiliation (based on the past Project Information) *help	2014 – 2024: 長崎大学, 医歯薬学総合研究科(薬学系), 教授 2012 – 2013: 長崎大学, 医歯(薬)学総合研究科, 教授 2009 – 2011: Nagasaki University, 大学院・医歯薬学総合研究科, 教授 2007 – 2008: Nagasaki University, 大学院・医歯薬学総合研究科, 准教授 2006: Nagasaki University, Graduate School of Biomedical Sciences, Associate Professor, 大学院医歯薬学総合研究科, 助教授 … More 2002 – 2005: Graduate School of Biomedical Sciences, Associate Professor, 大学院・医歯薬学総合研究科, 助教授 2004: 長崎大学, 医歯薬学総合研究科, 助教授 1999 – 2001: 長崎大学, 薬学部, 助教授 1996: 長崎大学, 薬学部, 助教授 1993: 長崎大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Physical pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Physical pharmacy Except Principal Investigator Medical pharmacy / Physical pharmacy / 医薬分子機能学
Keywords	Principal Investigator コントロールドリリース / 薬物速度論 / 吸収速度 / 肝臓 / 癌化学療法 / 抗癌薬 / 腹腔内投与 / 新規製剤 / intraperitoneal administration / liver disease … More / anticancer drug / liver / DDS / 放出制御 / がん / 製剤学 / 肝疾患 / 吸収 / ラット / がん化学療法 / 代謝阻害剤 / 肝臓内動態 / 徐放化製剤 / 薬物吸収 / DDS製剤 / pharmacokinetics / drug interaction / 粘性 / 肝障害 / 薬物相互作用 / oharmacokinetics / absorption rate / 抗癌剤 / 腹腔 / 製剤 / 粘性添加剤 / 薬物送達システム / 癌 / 臨床応用 / 遺伝子 / 薬理学 / 薬剤学 / 担癌動物 / 肝血流 / 肝臓表面 / 薬物動態 / ドラッグデリバリーシステム / 粘性製剤 / 局所滞留性 / 点滴速度 / 直接投与 / 投与形態 / 標的指向化 / 速度論 / 表面 … More Except Principal Investigator Drug delivery system / 薬物送達 / Drug targeting / Liver / DDS / 肝臓 / Anticancer agent / 5-Fluorouracil / 制癌剤 / 5-fluorouracil / Rat / Liver surface application / CMC / ラット / 肝臓表面投与 / Gene / Cancer / Pharmacy / 遺伝子 / 癌 / 薬学 / Clinical application / Pharmacokinetics / Ophthalmology / Polymer / Liposomes / Gene delivery / Topical application / ベクター / 速度論 / 動態 / 眼 / 局所 / 臨床応用 / 薬物速度論 / 眼科 / 高分子 / リポソーム / 遺伝子治療 / 局所適用 / Cancer chemotherapy / 抗癌剤 / 癌化学療法 / Viscous dosage form / Phenol red / 微量連続投与 / 単回投与 / 粘性製剤 / phenol red / 水溶性薬物 / 膜透過 / 結膜 / 角膜 / ペプチド医薬品 / 吸収促進剤 / 眼粘膜投与 / インスリン Less

臨床実装を目指した高機能な癌局所治療用二層型シート製剤の開発Principal Investigator
- Principal Investigator
  
  西田孝洋
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Nagasaki University
Application of the administration system to the peritoneal organ surface for regional chemotherapy by two-layer sheet formulation with anticancer drugs and gene medicinePrincipal Investigator
- Principal Investigator
  
  NISHIDA Koyo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Nagasaki University
Development of two-layer sheet formulation to improve local disposition and therapeutic effect of anticancer drugPrincipal Investigator
- Principal Investigator
  
  NISHIDA Koyo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Nagasaki University
Development of two-layer sheet formulation for application to liver surface to attain specific local chemotherapyPrincipal Investigator
- Principal Investigator
  
  NISHIDA Koyo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
Development of sheet formulation containing anticancer drugs and gene medicine for application to liver surfacePrincipal Investigator
- Principal Investigator
  
  NISHIDA Koyo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
Development of liver surface application formulation of anticancer drugs and gene medicine for clinical applicationPrincipal Investigator
- Principal Investigator
  
  NISHIDA Koyo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
Development of formulation for liver surface application to control distribution and period of anticancer drugs and gene medicinesPrincipal Investigator
- Principal Investigator
  
  NISHIDA Koyo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
Development of liver surface administration for the selective delivery of anticancer agent to the cancer region
- Principal Investigator
  
  NAKAMURA Junzo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagasaki University
Development of liver surface application form of anticancer drugs and genome medicine aiming to specific therapy of the diseased region in the organPrincipal Investigator
- Principal Investigator
  
  NISHIDA Koyo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
Development of topical gene delivery system for clinical application
- Principal Investigator
  
  SASAKI Hitoshi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagasaki University Hospital of Medicine and Dentistry
Targeting of anticancer drugs and genome medicine by utilizing absorption from the liver surfacePrincipal Investigator
- Principal Investigator
  
  NISHIDA Koyo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
Liver-selective delivery of 5-fluorouracil utilizing the absorption on the liver surface in rats
- Principal Investigator
  
  NAKAMURA Junzo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
肝臓表面からの特異的薬物集積に基づく新規肝疾患製剤の開発Principal Investigator
- Principal Investigator
  
  西田孝洋
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
Development of dosage form for the application to the liver surface for targeting of drug in the liver
- Principal Investigator
  
  NAKAMURA Junzo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
皮下注射に代わるインスリンの眼粘膜投与法の確立を目的とした基礎的研究
- Principal Investigator
  
  NAKAMURA Junzo
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Nagasaki University
肝臓の特定部位への薬物送達を目的とした肝臓組織表面への直接投与に関する基礎的研究Principal Investigator
- Principal Investigator
  
  西田孝洋
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University

[Journal Article] Development of a Two-Layered Sheet Formulation of 5-Fluorouracil for Application to Rat’s Livers to Ensure Controlled Release and Local Drug Disposition2023
- Author(s)
  Tomoaki Akagi, Yosuke Kariya, Hisashi Hamasaki, Miyako Sakaguchi, Hirotaka Miyamoto, Shintaro Fumoto, Koyo Nishida
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 71 Issue: 4 Pages: 277-281
- DOI
  10.1248/cpb.c22-00775
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2023-04-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06513
[Journal Article] Influence of Liver Intoxication by Carbon Tetrachloride or D-Galactosamine on Absorption of Fluorescein Isothiocyanate-Dextran-10 and Other Marker Compounds with Different Molecular Weights from the Rat Liver Surface2020
- Author(s)
  Miyamoto H, Tsuda K, Honda T, Tokunaga A, Fumoto S, Nishida K
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 2 Pages: 319-324
- DOI
  10.1248/bpb.b19-00686
- NAID
  130007793710
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-02-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06598, KAKENHI-PROJECT-19K07223
[Journal Article] A pH-Adjustable Tissue Clearing Solution That Preserves Lipid Ultrastructures: Suitable Tissue Clearing Method for DDS Evaluation2020
- Author(s)
  Fumoto Shintaro、Kinoshita Eriko、Ohta Keisuke、Nakamura Kei-ichiro、Hirayama Tasuku、Nagasawa Hideko、Hu Die、Okami Kazuya、Kato Riku、Shimokawa Shojiro、Ohira Naho、Nishimura Koyo、Miyamoto Hirotaka、Tanaka Takashi、Kawakami Shigeru、Nishida Koyo
- Journal Title
  
  Pharmaceutics
  
  Volume: 12 Issue: 11 Pages: 1070-1070
- DOI
  10.3390/pharmaceutics12111070
- NAID
  120006980771
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K12081, KAKENHI-PROJECT-19K11733, KAKENHI-PROJECT-18K06598, KAKENHI-PROJECT-16H06280
[Journal Article] Foreword2020
- Author(s)
  Koyo Nishida
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 68 Issue: 7 Pages: 559-559
- DOI
  10.1248/cpb.c20-ctf6807
- NAID
  130007867290
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2020-07-01
- Language
  English
- Open Access
- Data Source
  KAKENHI-PROJECT-18K06598
[Journal Article] Co-delivery Systems of Multiple Drugs Using Nanotechnology for Future Cancer Therapy2020
- Author(s)
  Fumoto Shintaro、Nishida Koyo
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 68 Issue: 7 Pages: 603-612
- DOI
  10.1248/cpb.c20-00008
- NAID
  130007867330
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2020-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K12081, KAKENHI-PROJECT-18K06598
[Journal Article] Targeted co-delivery of protein and drug to a tumor in vivo by sophisticated RGD-modified lipid-calcium carbonate nanoparticles2019
- Author(s)
  Peng Jian Qing、Fumoto Shintaro、Suga Tadaharu、Miyamoto Hirotaka、Kuroda Naotaka、Kawakami Shigeru、Nishida Koyo
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 302 Pages: 42-53
- DOI
  10.1016/j.jconrel.2019.03.021
- NAID
  120006987764
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12081, KAKENHI-PROJECT-18K06598
[Journal Article] Edaravone, a cytoprotective drug, enhances transgene expression mediated by lipoplexes in HepG2 cells and mice2018
- Author(s)
  Wang S, Fumoto S, Miyamoto H, Tanaka M, Nishida K
- Journal Title
  
  Int J Pharm
  
  Volume: 548 Issue: 1 Pages: 173-181
- DOI
  10.1016/j.ijpharm.2018.06.068
- NAID
  120006988001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06598, KAKENHI-PROJECT-16K18947
[Journal Article] 臓器表面投与法－消化器疾患に対する新たなDDS2018
- Author(s)
  Nishida K, Fumoto S
- Journal Title
  
  Drug Delivery System
  
  Volume: 33 Pages: 270-276
- NAID
  130007604256
- Open Access
- Data Source
  KAKENHI-PROJECT-18K06598
[Journal Article] Influence of vasomodulators and tumor transplantation on the disposition of 5-fluorouracil after application to the liver surface in rats2017
- Author(s)
  Kodama Y, Horishita M, Tokunaga A, Miyamoto H, Fumoto S, Sasaki H, Nakamura J, Nishida K
- Journal Title
  
  Biopharm. Drug Dispos.
  
  Volume: 38 Issue: 6 Pages: 367-372
- DOI
  10.1002/bdd.2073
- NAID
  130005024263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07891
[Journal Article] Effect of Metabolic Inhibitors on the Hepatic Disposition of 5-Fluorouracil after Application to the Rat Liver Surface2016
- Author(s)
  Kenta Shimokawa, Kazumi Wakasugi, Rei Tomonaga, Ken Utsunomiya, Hirotaka Miyamoto, Shintaro Fumoto, Koyo Nishida
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 39 Issue: 3 Pages: 361-367
- DOI
  10.1248/bpb.b15-00757
- NAID
  130005132312
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07891, KAKENHI-PROJECT-26860108, KAKENHI-PROJECT-16K18947
[Journal Article] Novel Diagnostic Method of Peritoneal Injury Using Dual Macromolecular Markers2014
- Author(s)
  Hirata H, Miyamoto H, Shimokawa K, Nakashima M, Nakayama M, Fumoto S, Nishida K
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 2 Pages: 262-267
- DOI
  10.1248/bpb.b13-00730
- NAID
  130003390929
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590053, KAKENHI-PROJECT-25350553
[Journal Article] Effect of absorption enhancers on the absorption of FD-4 as a poorly absorbable marker macromolecule from the liver surface in rats2014
- Author(s)
  Mine T, Miyamoto H, Yoshikawa N, Fumoto S, Sasaki H, Nakamura J, Nishida K
- Journal Title
  
  J Drug Del Sci Tech
  
  Volume: 24 Pages: 386-389
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590053
[Journal Article] Effect of viscous additives on the absorption and hepatic disposition of 5-fluorouracil (5-FU) after application to liver surface in rats2012
- Author(s)
  Kodama Y, Horishita M, Fumoto S, Mine T, Miyamoto H, Yoshikawa N, Hirata H, Sasaki H, Nakamura J, Nishida K
- Journal Title
  
  J Pharm Pharmacol
  
  Volume: 64 Issue: 10 Pages: 1438-1444
- DOI
  10.1111/j.2042-7158.2012.01514.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590053
[Journal Article] Relationship between lipophilicity and absorption from the liver surface of paraben derivatives and antipyrine in rats2011
- Author(s)
  Koyo Nishida
- Journal Title
  
  Journal of Pharmacy and Pharmacology
  
  Volume: 63(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590042
[Journal Article] Relationship between lipophilicity and absorption from the liver surface of paraben derivatives and antipyrine in rats2011
- Author(s)
  Nishida K, Kobayashi M, Miyamoto H, Yoshikawa N, Fumoto S, Sasaki H, Nakamura J
- Journal Title
  
  J. Pharm. Pharmacol.
  
  Volume: 63巻 Pages: 736-740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590042
[Journal Article] Rubbing gastric serosal surface enhances naked plasmid DNA transfer in rats and mice2011
- Author(s)
  Mine T, Ishii H, Nakajima S, Yoshikawa N, Miyamoto H, Nakashima M, Nakamura J, Fumoto S, Nishida K
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 34巻 Pages: 1514-1517
- NAID
  130001872450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590042
[Journal Article] 肝臓表面からの吸収を利用した薬物送達システムの開発とその展開2009
- Author(s)
  西田孝洋
- Journal Title
  
  薬学雑誌 129
  
  Pages: 925-932
- NAID
  130000135987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590042
[Journal Article] Absorption and distribution characteristics of 5-fluorouracil (5-FU) after an application to the liver surface in rats in order to reduce systemic side effects2008
- Author(s)
  Y. Kodama, S. Fumoto, J. Nishi, M. Nakashima, H. Sasaki, J. Nakamura, K. Nishida
- Journal Title
  
  Biological & Pharmaceutical Bulletin 31
  
  Pages: 1049-1052
- NAID
  110006663980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590042
[Journal Article] Change in pharmacokinetics of model compounds with different elimination processes in rats during hypothermia2007
- Author(s)
  Koyo Nishida
- Journal Title
  
  Biological & Pharmaceutical Bulletin 30
  
  Pages: 1763-1767
- NAID
  110006380265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590042
[Journal Article] Change in pharmacokinetics of model compounds with different elimination processes in rats during hypothermia2007
- Author(s)
  K. Nishida, M. Okazaki, R. Sakamoto, N. Inaoka, H. Miyake, S. Fumoto, J. Nakamura, M. Nakashima, H. Sasaki, M. Kakumoto and T. Sakaeda
- Journal Title
  
  Biological & Pharmaceutical Bulletin 30
  
  Pages: 1763-1767
- NAID
  110006380265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590042
[Journal Article] Effect of solution composition of plasmid DNA on gene transfection following liver surface administration in mice.2005
- Author(s)
  R.Hirayama, S.Fumoto, K.Nishida, M.Nakashima, H.Sasaki, J.Nakamura
- Journal Title
  
  Biol. Pharm. Bull. 28
  
  Pages: 2166-2169
- NAID
  110003666420
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Regional delivery of model compounds and 5-Fluorouracil to the liver by their application to the liver surface in rats : its implication for clinical use2005
- Author(s)
  Koyo Nishida
- Journal Title
  
  Pharmaceutical Research, 22-8
  
  Pages: 1331-1337
- NAID
  120006980897
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590029
[Journal Article] Regional delivery of model compounds and 5-fluorouracil to the liver by their application to the liver surface in rats : Its implication for clinical use2005
- Author(s)
  Koyo Nishida
- Journal Title
  
  Pharmaceutical Research 22(8)
  
  Pages: 1331-1337
- NAID
  120006980897
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590130
[Journal Article] Delivery advantage to the unilateral kedney by direct drug application to the kidney surface in rats and pharmacokinetic verification based on a physiological model.2005
- Author(s)
  K.Nishida, M, Kamenosono, A, Kuma, S.Fumoto, T.Mukai, M.Nakashima, H.Sasaki, J.Nakamura
- Journal Title
  
  Journal of Drug Targeting 13
  
  Pages: 215-223
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Regional delivery of model compounds and 5-fluorouracil to the liver by their application to the liver surface in rats : Its implication for clinical use2005
- Author(s)
  Koyo Nishida
- Journal Title
  
  Pharmaceutical Research 22・8
  
  Pages: 1331-1337
- NAID
  120006980897
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590130
[Journal Article] Delivery advantage to the unilateral kidney by direct drug application to the kidney surface in rats and pharmacokinetic verification based on a physiological model2005
- Author(s)
  Koyo Nishida
- Journal Title
  
  Journal of Drug Targeting, 13-4
  
  Pages: 215-223
- NAID
  120006980899
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590029
[Journal Article] Absorption characteristics of model compounds from the small intestinal serosal surface and a comparison with other organ surfaces2005
- Author(s)
  Koyo Nishida
- Journal Title
  
  Journal of Pharmacy and Pharmacology 57・8
  
  Pages: 1073-1077
- NAID
  120006980890
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590029
[Journal Article] Regional delivery of model compounds and 5-Fluorouracil to the liver by their application to the liver surface in rats : its implication for clinical use2005
- Author(s)
  Koyo Nishida
- Journal Title
  
  Pharmaceutical Research 22・8
  
  Pages: 1331-1337
- NAID
  120006980897
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590029
[Journal Article] Delivery advantage to the unilateral kidney by direct drug application to the kidney surface in rats and pharmacokinetic verification based on a physiological model2005
- Author(s)
  Koyo Nishida
- Journal Title
  
  Journal of Drug Targeting 13・4
  
  Pages: 215-223
- NAID
  120006980899
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590029
[Journal Article] Unilateral kidney-selective gene transfer following the administration of naked plasmid DNA to the kidney surface in mice.2005
- Author(s)
  R.Hirayama, K.Nishida, S.Fumoto, M, Nakashima, H.Sasaki, J.Nakamura
- Journal Title
  
  Biol. Pharm. Bull. 28
  
  Pages: 181-184
- NAID
  110003665796
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Absorption characteristics of model compounds from the small intestinal serosal surface and a comparison with other organ surfaces2005
- Author(s)
  Koyo Nishida
- Journal Title
  
  Journal of Pharmacy and Pharmacology, 57-8
  
  Pages: 1073-1077
- NAID
  120006980890
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590029
[Journal Article] Absorption characteristics of compounds with different molecular weights after application to the unilateral kindney surface in rats2004
- Author(s)
  Koyo Nishida
- Journal Title
  
  European Journal of Pharmaceutics and Biopharmaceutics 57・3
  
  Pages: 705-711
- Data Source
  KAKENHI-PROJECT-16590029
[Journal Article] Absorption characteristics of compounds with different molecular weights after application to the unilateral kidney surface in rats2004
- Author(s)
  Koyo Nishida
- Journal Title
  
  European Journal of Pharmaceutics and Biopharmaceutics 57・3
  
  Pages: 705-711
- NAID
  120006980808
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590029
[Journal Article] Prednisolone retention in integrated liposomes by chemical approach and pharmaceutical approach2004
- Author(s)
  Mugen Teshima, Koyo Nishida, Hitoshi Sasaki et al.
- Journal Title
  
  Journal of Controlled Release, 97-2
  
  Pages: 211-218
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Prednisolone retention in integrated liposomes by chemical approach and pharmaceutical approach2004
- Author(s)
  Mugen Teshima, Koyo Nishida, Hitoshi Sasaki et al.
- Journal Title
  
  Journal of Controlled Release 97・2
  
  Pages: 211-218
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Liver site-specific gene transfer following the administration of naked plasmid DNA to the liver surface in mice2004
- Author(s)
  Koyo Nishida, Hitoshi Sasaki, Junzo Nakamura et al.
- Journal Title
  
  Biological & Pharmaceutical Bulletin 27
  
  Pages: 1697-1699
- NAID
  110003608683
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] Absorption of phenolsulfonphthalein as a model across the mesenteric surface in rats to determine the drug absorption route after intraperitoneal administration2004
- Author(s)
  Koyo Nishida
- Journal Title
  
  Journal of Pharmacy and Pharmacology 56・5
  
  Pages: 683-687
- NAID
  120006980889
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590029
[Journal Article] Absorption characteristics of compounds with different molecular weights after application to the unilateral kidney surface in rats2004
- Author(s)
  Koyo Nishida
- Journal Title
  
  European Journal of Pharmaceutics and Biopharmaceutics, 57-3
  
  Pages: 705-711
- NAID
  120006980808
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590029
[Journal Article] Absorption of phenolsulfonphthalein as a model across the mesenteric surface in rats to determine the drug absorption route after intraperitoneal administration2004
- Author(s)
  Koyo Nishida
- Journal Title
  
  Journal of Pharmacy and Pharmacology, 56-5
  
  Pages: 683-687
- NAID
  120006980889
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590029
[Journal Article] Absorption of phenolsulfonphthalein as a model across the mesenteric surface in rats to determine the drug absorption route after intraperitoneal administration2004
- Author(s)
  Koyo Nishida
- Journal Title
  
  Journal of Pharmacy and Pharmacology 56
  
  Pages: 683-687
- NAID
  120006980889
- Data Source
  KAKENHI-PROJECT-16590029
[Journal Article] One-side-coated insert as a unique ophthalmic drug delivery system2003
- Author(s)
  Hitoshi Sasaki, Koyo Nishida, Mikiro Nakashima et al.
- Journal Title
  
  Journal of Controlled Release, 92-3
  
  Pages: 241-247
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Journal Article] One-side-coated insert as a unique ophthalmic drug delivery system2003
- Author(s)
  Hitoshi Sasaki, Koyo Nishida, Mikiro Nakashima et al.
- Journal Title
  
  Journal of Controlled Release 92・3
  
  Pages: 241-247
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590133
[Patent] 研磨剤を含有する核酸導入剤2011
- Inventor(s)
  麓伸太郎、西田孝洋
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Number
  2011-194260
- Filing Date
  2011-09-06
- Data Source
  KAKENHI-PROJECT-21590042
[Presentation] マウスとラットの種差による肝臓表面投与時の薬物吸収動態の差異とその予測2023
- Author(s)
  西田孝洋、袁飛、岩田栞、鳥越彩伽、宮元敬天、麓伸太郎
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06513
[Presentation] Studies on the effect of formulation additives on anti-tumor efficacy of bi-layer sheet loaded with doxorubicin2023
- Author(s)
  袁飛、満留菜央、宮元敬天、麓伸太郎、西田孝洋
- Organizer
  第39回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06513
[Presentation] 癌表面に貼付するドキソルビシン搭載シート製剤の抗腫瘍効果に及ぼす添加剤の影響2022
- Author(s)
  満留菜央、村上優衣、赤城友章、袁飛、宮元敬天、麓伸太郎、西田孝洋
- Organizer
  第38回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06513
[Presentation] Relationship between drug release from dialysis membrane and absorption from the mouse liver surface, aiming to predict viscous additives effect2022
- Author(s)
  Yuan Fei, Yuka Watanabe, Hikari Sada, Hirotaka Miyamoto, Shintaro Fumoto, Koyo Nishida
- Organizer
  第38回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06513
[Presentation] 癌病巣選択的治療に向けたドキソルビシン搭載シート製剤の腫瘍集積性と抗腫瘍効果の評価2022
- Author(s)
  満留菜央、村上優衣、赤城友章、袁飛、宮元敬天、麓伸太郎、西田孝洋
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K06513
[Presentation] ドキソルビシン搭載二層型シート製剤の腫瘍集積性と抗腫瘍効果の向上を目指した製剤設計2022
- Author(s)
  満留菜央、松本美月、袁飛、宮元敬天、麓伸太郎、西田孝洋
- Organizer
  第39回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-21K06513
[Presentation] Relationship between drug release from dialysis membrane and absorption from the mouse liver surface, aiming to predict viscous additives effect2021
- Author(s)
  YUAN FEI, Watanabe Yuka, Sada Hikari, Miyamoto Hirotaka, Fumoto Shintaro, Nishida Koyo
- Organizer
  第37回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-21K06513
[Presentation] 組織透明化法による肝臓表面投与後のDoxorubicinやマーカー物質の吸収性と分布の評価2021
- Author(s)
  坂口美也子、田中里奈子、袁飛、宮元敬天、麓伸太郎、西田孝洋
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-21K06513
[Presentation] 高選択的な局所化学療法に向けたDoxorubicin含有二層型シート製剤の各種組成における薬物放出性と体内分布評価2021
- Author(s)
  満留菜央、松本真由子、赤城友章、村上優衣、塚田凜、宮元敬天、麓伸太郎、西田孝洋
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06513
[Presentation] 組織透明化法による肝臓表面投与後の肝臓内Doxorubicinの空間分布評価2019
- Author(s)
  西田孝洋、田中里奈子、宮元敬天、麓伸太郎
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-18K06598
[Presentation] Doxorubicin含有肝臓表面適用二層型シート製剤からの薬物放出性と体内分布に及ぼす添加剤の影響2019
- Author(s)
  西田孝洋、赤城友章、松本真由子、佐田ひかり、宮元敬天、麓伸太郎
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06598
[Presentation] 5-Fluorouracilと代謝阻害剤を含有した肝臓表面適用二層型シート製剤の作製と肝臓内動態評価2019
- Author(s)
  西田孝洋、濵崎久司、前田理恵、宮元敬天、麓伸太郎
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K06598
[Presentation] 5-Fluorouracilと代謝阻害剤を含有した肝臓表面適用二層型シート製剤の動態評価2017
- Author(s)
  西田孝洋、前田理恵、浜崎久司、仮屋洋佑、下川研太、田中里奈子、宮元敬天、麓伸太郎
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-15K07891
[Presentation] 局所化学療法を目指した肝臓表面適用シート製剤の作製と担癌マウスを用いた薬物肝内分布の評価2016
- Author(s)
  鶴崎好美、仮屋洋佑、赤城友章、宮元敬天、麓伸太郎、西田孝洋
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島大学（鹿児島県・鹿児島市）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15K07891
[Presentation] Development of two-layer sheet formulation containing 5-FU and its pharmacokinetic consideration after application to rat liver surface2015
- Author(s)
  Koyo Nishida, Yosuke Kariya, Ken Utsunomiya Yoshimi Tsurusaki, Kenta Shimokawa, Hirotaka Miyamoto, Shintaro Fumoto
- Organizer
  日本薬物動態学会第30年会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15K07891
[Presentation] 肝臓表面投与法の臨床応用を目指した5-FU含有二層型シート製剤の開発2015
- Author(s)
  西田孝洋、仮屋洋佑、鶴崎好美、下川研太、宮元敬天、麓伸太郎
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-15K07891
[Presentation] 抗がん薬の肝臓表面投与を可能とするシート型製剤の開発とその最適化2014
- Author(s)
  仮屋洋佑、下川研太、朝長玲、若杉和美、平田春奈、宮元敬天、麓伸太郎、西田孝洋
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本市総合体育館（熊本市）
- Data Source
  KAKENHI-PROJECT-24590053
[Presentation] 肝臓表面投与法の臨床応用を目指した投与形態及び製剤開発に関する基礎的検討2013
- Author(s)
  下川研太, 朝長玲, 若杉和美, 仮屋洋佑, 宮元敬天, 麓伸太郎, 西田孝洋
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24590053
[Presentation] 乳酸グリコール酸共重合体を用いた肝臓表面適用シート製剤の基礎的検討2013
- Author(s)
  下川研太、仮屋洋佑、朝長玲、若杉和美、平田春奈、宮元敬天、麓伸太郎、西田孝洋
- Organizer
  バイオマテリアル学会九州講演会2013
- Place of Presentation
  熊本大学くすの木会館（熊本市）
- Data Source
  KAKENHI-PROJECT-24590053
[Presentation] 局所化学療法を目指した肝臓表面適用シート製剤の作製とその最適化2013
- Author(s)
  下川研太、仮屋洋佑、朝長玲、若杉和美、平田春奈、宮元敬天、麓伸太郎、西田孝洋
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎国際大学薬学部（佐世保市）
- Data Source
  KAKENHI-PROJECT-24590053
[Presentation] 新規投与形態DDSの製剤学的工夫2012
- Author(s)
  西田孝洋
- Organizer
  医療薬学フォーラム2012/第20回クリニカルファーマシーシンポジウム
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-24590053
[Presentation] 腹腔内の肝臓表面からの薬物吸収速度に及ぼす粘性添加剤の影響2011
- Author(s)
  西田孝洋
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  船堀タワーホール(東京都)
- Year and Date
  2011-05-29
- Data Source
  KAKENHI-PROJECT-21590042
[Presentation] Prediction of absorption rate from the liver surface in the presence of viscous additives by in vitro release experiment using semi-permeable membrane2010
- Author(s)
  Koyo Nishida
- Organizer
  日本薬物動態学会第25年会
- Place of Presentation
  埼玉県大宮ソニックシティ
- Year and Date
  2010-10-07
- Data Source
  KAKENHI-PROJECT-21590042
[Presentation] 粘性添加剤併用時の肝臓表面からの薬物吸収速度のin vitro透析膜実験系による予測2009
- Author(s)
  西田孝洋
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡市グランシップ
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-21590042
[Presentation] 肝臓表面投与後の5-FUの肝内分布に及ぼす血流や癌の影響2008
- Author(s)
  西田孝洋
- Organizer
  日本薬物動態学会第23回年会
- Place of Presentation
  熊本市
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19590042
[Presentation] 肝臓表面投与後の5-FUの肝内分布に及ぼす血流や癌の影響2008
- Author(s)
  西田孝洋, 兒玉幸修, 近藤理美, 西村知沙, 麓伸太郎, 中嶋幹郎, 佐々木均, 中村純三
- Organizer
  日本薬物動態学会第23回年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-19590042
[Presentation] 肝臓表面投与後の5-FUの肝臓集積性に対する血管収縮剤および代謝阻害剤の効果
- Author(s)
  西田孝洋、下川研太、兒玉幸修、若杉和美、宮元敬天、麓伸太郎
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  慶應義塾大学薬学部（東京都港区）
- Year and Date
  2014-07-30 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-24590053

1. NAKAMURA Junzo (30115901)

# of Collaborated Projects: 7 results

# of Collaborated Products: 4 results
2. NAKASHIMA Mikiro (00260737)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
3. FUMOTO Shintaro (70380988)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
4. MUKAI Takahiro (30284706)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SASAKI Hitoshi (00170689)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. SAKAEDA Toshiyuki (00304098)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KAWAKAMI Shieru (20322307)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. HIRATA Haruna

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
9. KODAMA Yukinobu (50448510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 新留琢郎 (26204210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MINE Toyoharu

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. MIYAMOTO Hirotaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
13. YOSHIKAWA Naoki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. SHIMOKAWA Kenta

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

NISHIDA Koyo 西田 孝洋

西田 孝洋 ニシダ コウヨウ

Research Projects

Research Products

Co-Researchers

臨床実装を目指した高機能な癌局所治療用二層型シート製剤の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Application of the administration system to the peritoneal organ surface for regional chemotherapy by two-layer sheet formulation with anticancer drugs and gene medicinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of two-layer sheet formulation to improve local disposition and therapeutic effect of anticancer drugPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of two-layer sheet formulation for application to liver surface to attain specific local chemotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of sheet formulation containing anticancer drugs and gene medicine for application to liver surfacePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of liver surface application formulation of anticancer drugs and gene medicine for clinical applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of formulation for liver surface application to control distribution and period of anticancer drugs and gene medicinesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of liver surface administration for the selective delivery of anticancer agent to the cancer region

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of liver surface application form of anticancer drugs and genome medicine aiming to specific therapy of the diseased region in the organPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of topical gene delivery system for clinical application

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Targeting of anticancer drugs and genome medicine by utilizing absorption from the liver surfacePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Liver-selective delivery of 5-fluorouracil utilizing the absorption on the liver surface in rats

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肝臓表面からの特異的薬物集積に基づく新規肝疾患製剤の開発Principal Investigator

Principal Investigator

Project Period (FY)

NISHIDA Koyo 西田孝洋

西田孝洋ニシダコウヨウ