KANDA Shigeru 神田滋

… Alternative Names

Researcher Number	20244048
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2006: Nagasaki University, Graduate School of Biomedical Sciences, Department of Molecular Microbiology and Immunology, Research Associate, 大学院医歯薬学総合研究科, 客員研究員 2002 – 2005: Nagasaki University Graduate School of Medical Science Department of Molecular Microbiology and Immunology, Associate Professor, 大学院・医歯薬学総合研究科, 助教授 2001: 長崎大学, 大学院・研究科, 助教授 2000 – 2001: Graduate School of Medicine, Nagasaki University Associate Professor, 大学院・医学研究科, 助教授 1999: 長崎大学, 医学部・附属病院, 助手 … More
Review Section/Research Field	Principal Investigator Urology / Urology Except Principal Investigator Urology
Keywords	Principal Investigator c-Fes / c-Fyn / Fes / FGF-2 / 血管内皮細胞 / endothelial cells / 血管新生 / Src / c-Src / 管腔形成 … More Except Principal Investigator 腎細胞癌 / PD-ECGF / Angiogenin / Paclitaxel / 塩基性線維芽細胞成長因子 / 代償性腎成長 / 骨形成因子 / 急性腎不全 / 腎再生 / 腎臓 / 表在性膀胱癌 / 血管新生 / 局所浸潤性膀胱癌 / 温存療法 / シグナル伝達 / 膀胱癌 / PDECGF / angiogenin / NMP-22 / hTERTmRNA / VEGF / Superficial bladder cancer / Neovascularization / Locally advanced bladder cancer / Bladder preservatiopn therapy / Signal transduction / アラキドン酸代謝 / シクロオキシゲナーゼ / 悪性腫瘍 / Arachidonic acid / Cyclooxygenase / Tumors / Renal cell carcinoma Less

Study of endothelial cell-specific signal transduction pathways and effect of chronic hypoxia. A strategy for the development of an effective antiangiogenic therapy.Principal Investigator
- Principal Investigator
  
  KANDA Shigeru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagasaki University
Identification of endothelial cell-specific signal transduction pathways leading to angiogenesisPrincipal Investigator
- Principal Investigator
  
  KANDA Shigeru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagasaki University
Identification of endothelial cell-specific signal transaction pathways leading to angiogenic cellular responsesPrincipal Investigator
- Principal Investigator
  
  KANDA Shigeru
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Nagasaki University Graduate School of Medical Science
The effects of arachidonic acid on urological tumors
- Principal Investigator
  
  KOGA Shigehiko
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagasaki University Graduate School of Medical Science
Prognostic significance of angiogenic growth factor in superficial bladder cancer
- Principal Investigator
  
  KANETAKE hiroshi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagasaki University
Identification of the target molecules for antiangiogenic therapyPrincipal Investigator
- Principal Investigator
  
  KANDA Shigeru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagasaki University
骨形成因子の腎への影響の検討
- Principal Investigator
  
  斉藤泰
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Nagasaki University
腎細胞癌増殖における塩基性線維芽細胞増殖因子の役割
- Principal Investigator
  
  KANETAKE hiroshi
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagasaki University

All 2007 2006 2005 2004 2003 Other

All Journal Article Book

[Book] Trends in Angiogenesis Research.2005
- Author(s)
  Kanda, S., Miyata, Y., Kanetake, H.
- Publisher
  Studies of the endothelial cell-specific signal transduction pathways. New paradigm for the development of potent anti-angiogenic therapies.
- Data Source
  KAKENHI-PROJECT-17591686
[Book] Progress in Angiogenesis Research2005
- Author(s)
  Kanda, Y.Miyata, H.Kanetake
- Publisher
  Nova Science Publishers, Inc. Hauppauge, NY, USA.(In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591698
[Book] Progress in Angiogenesis Research2005
- Author(s)
  Kanda, Y.Miyata, H.Kanetake
- Publisher
  (in press)
- Data Source
  KAKENHI-PROJECT-15591698
[Book] Trends in Angiogenesis Research2005
- Author(s)
  Shigeru Kanda, et al.
- Total Pages
  254
- Publisher
  Nova Science Publishers, Inc; New York
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] シグナル伝達分子に対する分子標的療法の現況と将来の展望2007
- Author(s)
  神田滋, 正野武文, 宮田康好, 金武洋
- Journal Title
  
  西日本泌尿器科 69(3)(印刷中)
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] Role of Src in angiopoietin 1-induced capillary morphogenesis of endothelial cells : Effect of chronic hypoxia on Src inhibition by PP2.2007
- Author(s)
  Kanda S, Kanetake H, Miyata Y.
- Journal Title
  
  Cellular Signaling 19(3)
  
  Pages: 472-80
- NAID
  120001642743
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] Role of Src in angiopoietin 1-induced capillary morphogenesis of endothelial cells : Effect of chronic hypoxia on Src inhibition by PP2.2007
- Author(s)
  Shigeru Kanda, et al.
- Journal Title
  
  Cellular Signaling 19(3)
  
  Pages: 472-480
- NAID
  120001642743
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] Role of Src in angiopoietin 1-induced capillary morphogenesis of endothelial cells : Effect of chronic hypoxia on Src inhibition by PP2.2007
- Author(s)
  Shigeru Kanda et al.
- Journal Title
  
  Cellular Signaling. 19(3)
  
  Pages: 472-80
- NAID
  120001642743
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] HGF-induced capillary morphogenesis of endothelial cells is regulated by Src.2006
- Author(s)
  Shigeru Kanda, et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications 344(2)
  
  Pages: 617-622
- NAID
  120001642740
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] Current status and perspective of antioangiogenic therapy for cancer : urinary cancer (REVIEW).2006
- Author(s)
  Shigeru Kanda, et al.
- Journal Title
  
  International Journal of Clinical Oncology 11(2)
  
  Pages: 90-107
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] Fibroblast growth factor-2 induces the activation of Src through Fes, which regulates focal adhesion disassembly.2006
- Author(s)
  Shigeru Kanda, et al.
- Journal Title
  
  Experimental Cell Research. 312(16)
  
  Pages: 3015-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] Fibroblast growth factor-2 induces the activation of Src through Fes, which regulates focal adhesion disassembly.2006
- Author(s)
  Shigeru Kanda, et al.
- Journal Title
  
  Experimental Cell Research 312(16)
  
  Pages: 3015-3022
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] levated expression of ERK 2 in human tumor cells chronically treated with PD98059.2006
- Author(s)
  Kanda S, Kanetake H, Miyata Y.
- Journal Title
  
  Biochemical and Biophysical Research Communications 345(4)
  
  Pages: 1481-6
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] HGF-induced capillary morphogenesis of endothelial cells in regulated by Src.2006
- Author(s)
  Kanda S, Kanetake H, Miyata Y.
- Journal Title
  
  Biochemical and Biophysical Research Communications 344(2)
  
  Pages: 617-22
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] Fibroblast growth factor-2 induces the activation of Src through Fes, which regulates focal adhesion disassembly.2006
- Author(s)
  Kanda S, Miyata Y, Kanetake H, Smithgall TE.
- Journal Title
  
  Experimental Cell Research 312(16)
  
  Pages: 3015-22
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] Current status and perspective of antiangiogenic therapy for cancer : urinary cancer (REVIEW).2006
- Author(s)
  Shigeru Kanda et al.
- Journal Title
  
  International Journal of Clinical Oncology. 11(2)
  
  Pages: 90-107
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] Elevated expression of ERK 2 in human tumor cells chronically treated with PD98059.2006
- Author(s)
  Shigeru Kanda, et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications 345(4)
  
  Pages: 1481-1486
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] Current status and perspective of antiangiogenic therapy for cancer : urinary cancer.2006
- Author(s)
  Kanda S, Miyata Y, Kanetake H.
- Journal Title
  
  International Journal of Clinical Oncology 11(2)
  
  Pages: 90-107
- NAID
  10018174756
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells.2005
- Author(s)
  S.Kanda, Y.Miyata, H.Kanetake
- Journal Title
  
  Journal of Cellular Biochemistry 94
  
  Pages: 835-847
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] Pigment epithelium-derived factor inhibits fibroblast growth factor-2-induced capillary morphogenesis of endothelial cells through c-Fyn.2005
- Author(s)
  Shigeru Kanda, et al.
- Journal Title
  
  Journal of Cell Science 118(Pt 5)
  
  Pages: 961-970
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] Pigment epithelium-derived factor inhibits fibroblast growth factor-2-induced capillary morphogenesis of endothelial cells through c-Fyn.2005
- Author(s)
  Shigeru Kanda, Yasushi Mochizuki, Takao Nakamura, Yasuyoshi Miyata, Toshifumi Matsuyama, Hiroshi Kanetake
- Journal Title
  
  Journal of Cell Science 118
  
  Pages: 961-970
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] Aniopoietin 1 is mitogenic for cultured endothelial cells.2005
- Author(s)
  Shigeru Kanda, et al.
- Journal Title
  
  Cancer Research 65
  
  Pages: 6820-6827
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] Aniopoietin 1 is mitogenic for cultured endothelial cells.2005
- Author(s)
  Shigeru Kanda, et al.
- Journal Title
  
  Cancer Research 65(15)
  
  Pages: 6820-6827
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells.2005
- Author(s)
  Shigeru Kanda, et al.
- Journal Title
  
  Journal of Cellular Biochemistry 94
  
  Pages: 835-847
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] Pigment epithelium-derived factor inhibits fibroblast growth factor-2-induced capillary morphogenesis of endothelial cells through c-Fyn2005
- Author(s)
  S.Kanda, Y.Mochizuki, T.Nakamura, Y.Miyata, T.Matsuyama, H.Kanetake
- Journal Title
  
  Journal of Cell Science 118
  
  Pages: 961-970
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells.2005
- Author(s)
  Shigeru Kanda, Yasuyoshi Mityata, Hiroshi Kanetake
- Journal Title
  
  Journal of Cellular Biochemistry 94
  
  Pages: 835-847
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells.2005
- Author(s)
  Shigeru Kanda, et al.
- Journal Title
  
  Journal of Cellular Biochemistry 94(4)
  
  Pages: 835-847
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] Pigment epithelium-derives factor inhibits fibroblast growth factor-2-induced capillary morphogenesis of endothehial cells through e-Fyn2005
- Author(s)
  S.Kanda, Y.Moshizuki, T.Nakamura, Y.Miyata, T.Matsuyama, H.Kanetake
- Journal Title
  
  Journal of Cell Science (In press)
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] Studies of the endothelial cell-specific signal transduction pathways. New paradigm for the development of potent anti-angiogenic therapies.2005
- Author(s)
  Shigeru Kanda et al.
- Journal Title
  
  Trends in Angiogenesis Research. (New York : Nova Science Publishers, Inc)
  
  Pages: 43-69
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] Pigment epithelium-derived factor inhibits fibroblast growth factor-2-induced capillary morphogenesis of endothelial cells through c-Fyn.2005
- Author(s)
  Shigeru Kanda, et al.
- Journal Title
  
  Journal of Cell Science 118
  
  Pages: 961-970
- Data Source
  KAKENHI-PROJECT-17591686
[Journal Article] T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells.2005
- Author(s)
  S.Kanda, Y.Mityata, H.Kanetake
- Journal Title
  
  Journal of Cellular Biochemistry 94
  
  Pages: 835-847
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] Fibroblast growth factor-2-mediated capillary morphogenesis of endothelial cells requires signals via Fit-1/vascular endothelial growth factor receptor-1. Possible involvement of c-Akt.2004
- Author(s)
  S.Kanda, Y.Miyata, H.Kanetake
- Journal Title
  
  Journal of Biological Chemistry 279(6)
  
  Pages: 4007-4016
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] Role of focal adhesion formation in migration and morphogenesis of endothelial cells.2004
- Author(s)
  Shigeru Kanda, Yasuyoshi Mityata, Hiroshi Kanetake
- Journal Title
  
  Cellular Signaling 16
  
  Pages: 1273-1281
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] Fibroblast growth factor-2-mediated capillary morphogenesis of endothelial cells requires signals via Flt-1/vascular endothelial growth factor receptor-1. Possible involvement of c-Akt.2004
- Author(s)
  Shigeru Kanda, Yasuyoshi Miyata, Hiroshi Kanetake
- Journal Title
  
  Journal of Biological Chemistry 279(6)
  
  Pages: 4007-4016
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] Role of focal adhesion formation in migration and morphogenesis of endothelial cells.2004
- Author(s)
  S.Kanda, Y.Miyata, H.Kanetake
- Journal Title
  
  Cellular Signaling 16
  
  Pages: 1273-1281
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] Fibroblast growth factor-2-mediated capillary morphogenesis of endothelial cells requires signals via Flt-1/vascular endothelial growth factor receptor-1. Possible involvement of c-Akt.2004
- Author(s)
  S.Kanda, Y.Mityata, H.Kanetake
- Journal Title
  
  Journal of Biological Chemistry 279(6)
  
  Pages: 4007-4016
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] Role of focal adhesion formation in migration and morphogonesis of endothelial cells.2004
- Author(s)
  S.Kanda, Y.Mityata, H.Kanetaka
- Journal Title
  
  Cellular Signaling 16
  
  Pages: 1273-1281
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] Sonic hedgehog induces capillary morphogenesis by endothelial cells through phosphoinositide 3-kinase.2003
- Author(s)
  Shigeru Kanda, Takashi Suematsu, Yasuyoshi Miyata, Yasushi Mochizuki, Koichiro Nomata, Hiroshi Kanetake
- Journal Title
  
  Journal of Biological Chemistry 278(10)
  
  Pages: 8244-8249
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] Sonic hedgehog induces capillary morphogenesis by endothelial cells through phosphoinositide2003
- Author(s)
  S.Kanda, T.Suematsu, Y.Mityata, Y.Mochizuki, K.Nomata, H.Kanetake
- Journal Title
  
  Journal of Biological Chemistry 278(10)
  
  Pages: 8244-8249
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] Stromal cell-derived factor-1a induces tube-like structure formation of endothelial cells through phosphoinositide 3-kinase.2003
- Author(s)
  S.Kanda, Y.Mochizuki, H.Kanetake
- Journal Title
  
  Journal of Biological Chemistry 278(1)
  
  Pages: 257-262
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] Stromal cell-derived factor-1a induces tube-like structure formation of endothelial cells through phosphoinositide 3-kinase.2003
- Author(s)
  Shigeru Kanda, Yasushi Mochizuki, Hiroshi Kanetake
- Journal Title
  
  Journal of Biological Chemistry 278(1)
  
  Pages: 257-262
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591698
[Journal Article] Studies of the endothelial cell-specific signal transduction pathways. New paradigm for the development of potent anti-angiogenic therapies.
- Author(s)
  Shigeru Kanda, Yasuyoshi Miyata, Hiroshi Kanetake
- Journal Title
  
  Progress in Angiogenesis Research(Nova Science Publishers, Inc.Hauppauge, NY, USA.) (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591698

1. KANETAKE hiroshi (50100839)

# of Collaborated Projects: 5 results

# of Collaborated Products: 18 results
2. NOMATA Koichiro (80189430)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KOGA Shigehiko (10205354)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. OTSURU Akira (00233198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HAYASHI Toadyish (20253651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 斉藤泰 (70039832)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 井川掌 (40295069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KANDA Shigeru 神田 滋

神田 滋 カンダ シゲル

Research Projects

Research Products

Co-Researchers

Study of endothelial cell-specific signal transduction pathways and effect of chronic hypoxia. A strategy for the development of an effective antiangiogenic therapy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of endothelial cell-specific signal transduction pathways leading to angiogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of endothelial cell-specific signal transaction pathways leading to angiogenic cellular responsesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effects of arachidonic acid on urological tumors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prognostic significance of angiogenic growth factor in superficial bladder cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of the target molecules for antiangiogenic therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

骨形成因子の腎への影響の検討

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

腎細胞癌増殖における塩基性線維芽細胞増殖因子の役割

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Trends in Angiogenesis Research.2005

Author(s)

Publisher

Data Source

[Book] Progress in Angiogenesis Research2005

Author(s)

Publisher

Description

Data Source

[Book] Progress in Angiogenesis Research2005

Author(s)

Publisher

Data Source

[Book] Trends in Angiogenesis Research2005

Author(s)

Total Pages

Publisher

Description

Data Source

[Journal Article] シグナル伝達分子に対する分子標的療法の現況と将来の展望2007

Author(s)

Journal Title

Data Source

[Journal Article] Role of Src in angiopoietin 1-induced capillary morphogenesis of endothelial cells : Effect of chronic hypoxia on Src inhibition by PP2.2007

Author(s)

Journal Title

NAID

KANDA Shigeru 神田滋

神田滋カンダシゲル