ARIMA Kunimasa 有馬邦正

Researcher Number	20250227
Affiliation (based on the past Project Information) *help	2016: 国立病院機構小諸高原病院, 院長 2012: 明治薬科大学, 薬学部, 助教 2012: 独立行政法人国立精神・神経医療研究センター病院, 第一精神診療部, 部長 2012: 独立行政法人国立精神・神経医療研究センター, 病院第一精神診療部, 部長 2011: 独立行政法人国立精神・神経医療研究センター, 病院・第一精神診療部, 部長 … More 2010: 国立精神・神経医療研究センター病院, 第一精神診療部, 部長 2009: 国立精神・神経センター, 病院・第一病棟部, 部長 1999: 財団法人東京都医学研究機構, 東京都精神医学総合研究所, 副参事研究員 1998: Tokyo Institute of Psychiatry, Department of Ultrastructure and Histochemistry,, 超微形態研究部門, 副参事研究員 1997: Tokyo Institute of Psychiatry, Dept.of Ultrastructure and Histochemistry, Vice Councilor of Research, 超微形態研究部門, 副参事研究員 1997: (財)東京都精神医学総合研究所, 超微形態部門, 副参事研究員 1996: (財)東京都精神医学総合研究所, 副参事研究員 1996: 財団法人東京都精神医学総合研究所, 超微形態研究部門, 副参事研究員 1993 – 1994: 国立精神・神経センター, 神経研究所・疾病研究第3部, 研究員 Less
Review Section/Research Field	Principal Investigator Psychiatric science Except Principal Investigator Nerve anatomy/Neuropathology / Psychiatric science / Nerve anatomy/Neuropathology / Radiation science
Keywords	Principal Investigator synuclein / tau / NACP / Tau protein / Senile plaque / Paired helical filaments / Gliosis / Astrocyte / Amyloid / Corticonigral degeneration … More / Neuropil threads / fibrinogenesis / conformation disease / Neuronal death / multiple system atrophy / Parkinson's disease / electron microscopy / neuronal death / neurofibrillary tangles / Lewy body / filament pathology / 星状膠細胞 / 多系統萎縮症 / コンフォーメーション病 / 線維凝集 / 封入体形成 / コンフォメーション病 / シヌクレイン / 神経細胞死 / 神経突起変性 / パーキンソン病 / Electron microscopy / Alzhemer's disease / Electon microscopy / Alzheimer's disease / Dementia / Fine structure / Nieurofibrillary tangles / Gallyas-Braak staining / Cerebral cortex / Progressive supranuclear palsy / 免疫組織化学 / neuropil threads / Gallyas‐Braak染色 / 痴呆 / 神経原線維変化 / 超微形態 / Gallyas-Braak染色 / 大脳皮質 / 進行性核上麻痺 … More Except Principal Investigator RT-PCR / バイオインフォマティクス / 分子ネットワーク / 結合タンパク質 / 標的遺伝子 / オミックス / AGTPBP1 / NNA1 / Smcr8 / FTD / ALS / C9orf72 / central nervous system / viral infection / autopsy brain tissue / schizophrenia / Boma disease virus / p24 / 脳 / 脳ウイルス感染 / ボルナ病ウイルス / ヒト剖検脳 / 精神分裂病 / ブロテインアレイ / ブロテオミクス / インターラクトーム / 次世代シークエンサー / 神経細胞死 / 筋萎縮性側索硬化症 / TDP-43 / PSRCT / 拡散テンソ / ASL / 拡散テンソル / 脳血流 / MRI / 変性疾患 Less

Molecular network analysis of ALS/FTD-responsible gene C9orf72
- Principal Investigator
  
  Satoh Jun-ichi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Meiji Pharmaceutical University
Comprehensive analysis of TDP-43 target genes and binding proteins
- Principal Investigator
  
  SATOH Jun-ichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Meiji Pharmaceutical University
Integrative morphological & functioning imaging analysis in patients with neurodegenerative disease
- Principal Investigator
  
  SATO Noriko
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  National Center of Neurology and Psychiatry
Immunocytochemical studies of NACP/α-synclein mediated neuronal degenerationPrincipal Investigator
- Principal Investigator
  
  ARIMA Kunimasa, 有馬邦正
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Tokyo Metropolitan Organization of Medical Research
Detection of Boma disease virus genome in autopsy brains among people with psychiatric disoders
- Principal Investigator
  
  IKEDA Kazuhiko
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Tokyo Institute of Psychiatry
Immunocytochemical and ultrastructural examination of amyloid plaques in the brains with Alzheimer-type dementia.Principal Investigator
- Principal Investigator
  
  ARIMA Kunimasa
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Tokyo Institute of Psychiatry
Involvement of the cerebral cortex in progressive supranuclear palsy : immunohistochemistry and electron microscopical examination of the modified Gallyas-Braak method.Principal Investigator
- Principal Investigator
  
  ARIMA Kunimasa
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY

All 2015 2014 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Bioinformatics data mining approach suggests coexpression of AGTPBP1 with an ALS-linked gene C9orf72.2015
- Author(s)
  Kitano S, Kino Y, Yamamoto Y, Takitani M, Miyoshi J, Ishida T, Saito Y, Arima K, Satoh J
- Journal Title
  
  Journal of Central Nervous System Disease
  
  Volume: 7 Pages: 15-26
- DOI
  10.4137/jcnsd.s24317
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430054
[Journal Article] Immunohistochemical characterization of CD33 expression on microglia in Nasu-Hakola disease brains.2015
- Author(s)
  Satoh J, Kino Y, Motohashi N, Ishida T, Yagishita S, Jinnai K, Arai N, Nakamagoe K, Tamaoka A, Saito Y, Arima K
- Journal Title
  
  Neuropathology
  
  Volume: 35 Issue: 6 Pages: 529-537
- DOI
  10.1111/neup.12222
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430054, KAKENHI-PROJECT-26460901
[Journal Article] LC3, an autophagosome marker, is expressed on oligodendrocytes in Nasu-Hakola disease brains.2014
- Author(s)
  Satoh J, Motohashi N, Kino Y, Ishida T, Yagishita S, Jinnai K, Arai N, Nakamagoe K, Tamaoka A, Saito Y, Arima K.
- Journal Title
  
  Orphanet J Rare Dis
  
  Volume: 9 Issue: 1 Pages: 1-11
- DOI
  10.1186/1750-1172-9-68
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590869, KAKENHI-PROJECT-24591249, KAKENHI-PROJECT-25430054, KAKENHI-PROJECT-26460901
[Journal Article] PLD3 is accumulated on neuritic plaques in Alzheimer’s disease brains.2014
- Author(s)
  Satoh J, Kino Y, Yamamoto Y, Kawana N, Ishida T, Saito Y, Arima K.
- Journal Title
  
  Alzheimer’s Research and Therapy
  
  Volume: 6 Issue: 5-8
- DOI
  10.1186/s13195-014-0070-5
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430054
[Journal Article] LC3, an autophagosome marker, is expressed on oligodendrocytes in Nasu-Hakola disease brains.2014
- Author(s)
  Satoh J, Motohashi N, Kino Y, Ishida T, Yagishita S, Jinnai K, Arai N, Nakamagoe K, Tamaoka A, Saito Y, Arima K
- Journal Title
  
  Orphanet Journal of Rare Diseases
  
  Volume: NA
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430054
[Journal Article] TMEM106B expression is reduced in Alzheimer’s disease brains.2014
- Author(s)
  Satoh J, Kino Y, Kawana N, Yamamoto Y, Ishida T, Saito Y, Arima K.
- Journal Title
  
  Alzheimer’s Research and Therapy
  
  Volume: 6 Issue: 2
- DOI
  10.1186/alzrt247
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430054
[Journal Article] Reactive astrocytes express the potassium channel Kir4.1 inactive multiple sclerosis lesions.2013
- Author(s)
  Satoh J, Tabunoki H, Ishida T, Saito Y,Konno H, Arima K.
- Journal Title
  
  Clinical andExperimental Immunology
  
  Volume: in press Issue: 1 Pages: 19-28
- DOI
  10.1111/cen3.12011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500322, KAKENHI-PROJECT-25430054
[Journal Article] Reactive astrocytes and perivascular macrophages express NLRP3 inflammasome in active demyelinating lesions of multiple sclerosis and necrotic lesions of neuromyelitis optica and cerebral infarction.2013
- Author(s)
  Kawana N, Yamamoto Y, Ishida T, Saito Y, Konno H, Arima K, Satoh J
- Journal Title
  
  Clinical and Experimental Neuroimmunology
  
  Volume: 4 Issue: 3 Pages: 296-304
- DOI
  10.1111/cen3.12068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430054
[Journal Article] Accumulation of a repulsiveaxonal guidance molecule RGMa in amyloidplaques: a possible hallmark of regenerativefailure in Alzheimer's disease brains.2013
- Author(s)
  Satoh J, Tabunoki H, Ishida T, Saito Y,Arima K.
- Journal Title
  
  Neuropathology and Applied Neurobiology
  
  Volume: 39(2) Issue: 2 Pages: 109-120
- DOI
  10.1111/j.1365-2990.2012.01281.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500322, KAKENHI-PROJECT-25430054
[Journal Article] Ubiquilin-1 immunoreactivity isconcentrated on Hirano bodies anddystrophic neurites in Alzheimer's diseasebrains.2013
- Author(s)
  Satoh J, Tabunoki H, Ishida T, Saito Y,Arima K.
- Journal Title
  
  Neuropathology and Applied Neurobiology
  
  Volume: in press Issue: 7 Pages: 817-830
- DOI
  10.1111/nan.12036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500322, KAKENHI-PROJECT-25430054
[Journal Article] A survey of TREM2 antibodies reveals neuronal but not microglial staining in formalin-fixed paraffin-embedded postmortem Alzheimer’s brain tissues.2013
- Author(s)
  Satoh J, Kawana N, Yamamoto Y, Ishida T, Saito Y, Arima K
- Journal Title
  
  Alzheimer’s Research and Therapy
  
  Volume: 5 Issue: 4 Pages: 30-30
- DOI
  10.1186/alzrt184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430054
[Journal Article] Phosphorylated Sykexpression is enhanced in Nasu-Hakoladisease brains.2012
- Author(s)
  Jinnai K, Futamura N, Kobayashi M,Toyoshima I, Yoshioka T, Enomoto K, AraiN, SaitoY, Arima K.
- Journal Title
  
  Neuropathology
  
  Volume: 32(2) Issue: 2 Pages: 149-157
- DOI
  10.1111/j.1440-1789.2011.01256.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500322, KAKENHI-PROJECT-22590968
[Journal Article] Dystrophic neurites expressC9orf72 in Alzheimer's disease brains.2012
- Author(s)
  Satoh J, Tabunoki H, Ishida T, Saito Y,Arima K.
- Journal Title
  
  Alzheimer's Research and Therapy
  
  Volume: 4(4) Issue: 4
- DOI
  10.1186/alzrt136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500322
[Journal Article] Immunohistochemicalcharacterization of gamma-secretaseactivating protein expression in Alzheimer'sdisease brains.2012
- Author(s)
  Satoh J, Tabunoki H, Ishida T, Saito Y, Arima K.
- Journal Title
  
  Neuropathology and AppliedNeurobiology
  
  Volume: 38(2) Issue: 2 Pages: 132-141
- DOI
  10.1111/j.1365-2990.2011.01206.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500322, KAKENHI-PROJECT-22590968
[Journal Article] Immunohistochemical characterization of microglia in Nasu-Hakola disease brains.2011
- Author(s)
  Satoh J, Tabunoki H, Ishida T, Yagishita S, Jinnai K, Futamura N, Kobayashi M, Toyoshima I, Yoshioka T, Enomoto K, Arai N, Arima K
- Journal Title
  
  Neuropathology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500322
[Journal Article] Immunohistochemicalcharacterization of microglia inNasu-Hakola disease brains.2011
- Author(s)
  Satoh J, Tabunoki H, Ishida T, Yagishita S,Jinnai K, Futamura N, Kobayashi M,Toyoshima I, Yoshioka T, Enomoto K, AraiN, Arima K.
- Journal Title
  
  Neuropathology
  
  Volume: 31(4) Issue: 4 Pages: 363-375
- DOI
  10.1111/j.1440-1789.2010.01174.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500322
[Journal Article] Aberrant microRNA expression in the brains of neurodegenerative diseases : miR-29a decreased in Alzheimer disease brains targets neuron navigator-3.2010
- Author(s)
  Shioya M, Obayashi S, Tabunoki H, Arima K, Saito Y, Ishida T, Satoh J
- Journal Title
  
  Neuropathology and Applied Neurobiology
  
  Volume: 36 Pages: 320-330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500322
[Journal Article] Protein microarray analysis identifies cyclic nucleotide phosphodiesterase as an interactor of Nogo-A.2010
- Author(s)
  Sumiyoshi K, Obayashi S, Tabunoki H, Arima K, Satoh J
- Journal Title
  
  Neuropathology
  
  Volume: 30 Pages: 7-14
- NAID
  10029319754
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500322
[Journal Article] TDP-43 dimerizes in human cells in culture.2010
- Author(s)
  Shiina Y, Arima K, Tabunoki H, Satoh J.
- Journal Title
  
  Cellular and Molecular Neurobiology
  
  Volume: 30(4) Issue: 4 Pages: 641-652
- DOI
  10.1007/s10571-009-9489-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500322
[Journal Article] TDP-43 dimerizes in human cells in culture.2010
- Author(s)
  Shiina Y, Arima K, Tabunoki H, Satoh J
- Journal Title
  
  Cellular and Molecular Neurobiology
  
  Volume: 30 Pages: 641-652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500322
[Journal Article] AberrantmicroRNA expression in the brains ofneurodegenerative diseases: miR-29adecreased in Alzheimer disease brainstargets neuro navigator-3.2010
- Author(s)
  Shioya M, Obayashi S, Tabunoki H, ArimaK, Saito Y, Ishida T, Satoh J.
- Journal Title
  
  Neuropathologyand Applied Neurobiology
  
  Volume: 36(49) Issue: 4 Pages: 320-330
- DOI
  10.1111/j.1365-2990.2010.01076.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500322
[Presentation] Alzheimer病脳のIba1陽性microgliaはTREM2を発現しない.2014
- Author(s)
  佐藤準一、紀嘉浩、川名夏生、山本洋司、石田剛、齊藤祐子、有馬邦正
- Organizer
  第55回日本神経病理会総会
- Place of Presentation
  東京
- Year and Date
  2014-06-07
- Data Source
  KAKENHI-PROJECT-25430054
[Presentation] Immunohistochemical characterization ofgamma-secretase activating protein (GSAP)expression in Alzheimer's disease brains.2012
- Author(s)
  Satoh J, Tabunoki H, Arima K.
- Organizer
  The 64th Annual Meeting of American Academy of Neurology. New Orleans
- Place of Presentation
  LA,USA
- Year and Date
  2012-04-25
- Data Source
  KAKENHI-PROJECT-22500322
[Presentation] Immunohistochemical characterization ofmicroglia in Nasu-Hakola disease brains.2011
- Author(s)
  Satoh J, Tabunoki H, Arima K.
- Organizer
  The 63rd Annual Meeting of AmericanAcademy of Neurology.
- Place of Presentation
  Honolulu, HI, USA
- Year and Date
  2011-04-12
- Data Source
  KAKENHI-PROJECT-22500322
[Presentation] Immunohistochemical characterization of microglia in Nasu-Hakola disease brains2011
- Author(s)
  Satoh J, Tabunoki H, Arima K
- Organizer
  63rd Annual Meeting of American Academy of Neurology
- Place of Presentation
  Honolulu, USA
- Year and Date
  2011-04-12
- Data Source
  KAKENHI-PROJECT-22500322
[Presentation] Immunopathogenesis ofNasu-Hakola disease brain lesions.2010
- Author(s)
  Satoh J, Tabunoki H, Kim SU, Ishida T,Jinnai K, Arima K.
- Organizer
  The 14thInternational Congress of Immunology.
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-22500322
[Presentation] Immunopathogenesis of brain lesions of Nasu-Hakola disease.2010
- Author(s)
  Satoh J, Tabunoki H, Kim SU, Ishida T, Jinnai K, Arima K
- Organizer
  10th International Congress of Neuroimmunology
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2010-10-27
- Data Source
  KAKENHI-PROJECT-22500322
[Presentation] Immunopathogenesis of Nasu-Hakola disease brain lesions.2010
- Author(s)
  Satoh J, Tabunoki H, Kim SU, Ishida T, Jinnai K, Arima K
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-22500322

1. ARIMA Kunimasa (40124482)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. SATOH Jun-ichi (30274591)

# of Collaborated Projects: 2 results

# of Collaborated Products: 26 results
3. SATO Noriko (10322017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. IKEDA Kazuhiko (30124663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KANDA Takashi (40204797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IKUTA Kazuyoshi (60127181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TASHIRO Masato (90111343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SHIMOMURA Yuko (70332377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. UEDA Kenji (90261180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 天竺桂弘子 (80434190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
11. IRITANI Shuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 泉山洋子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SHIMOMURA Yoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 中馬越清隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 玉岡晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ARIMA Kunimasa 有馬 邦正

Research Projects

Research Products

Co-Researchers

Molecular network analysis of ALS/FTD-responsible gene C9orf72

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive analysis of TDP-43 target genes and binding proteins

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Integrative morphological & functioning imaging analysis in patients with neurodegenerative disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunocytochemical studies of NACP/α-synclein mediated neuronal degenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Detection of Boma disease virus genome in autopsy brains among people with psychiatric disoders

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunocytochemical and ultrastructural examination of amyloid plaques in the brains with Alzheimer-type dementia.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of the cerebral cortex in progressive supranuclear palsy : immunohistochemistry and electron microscopical examination of the modified Gallyas-Braak method.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Bioinformatics data mining approach suggests coexpression of AGTPBP1 with an ALS-linked gene C9orf72.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunohistochemical characterization of CD33 expression on microglia in Nasu-Hakola disease brains.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] LC3, an autophagosome marker, is expressed on oligodendrocytes in Nasu-Hakola disease brains.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PLD3 is accumulated on neuritic plaques in Alzheimer’s disease brains.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] LC3, an autophagosome marker, is expressed on oligodendrocytes in Nasu-Hakola disease brains.2014

Author(s)

Journal Title

Data Source

[Journal Article] TMEM106B expression is reduced in Alzheimer’s disease brains.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reactive astrocytes express the potassium channel Kir4.1 inactive multiple sclerosis lesions.2013

Author(s)

Journal Title

DOI

Data Source

ARIMA Kunimasa 有馬邦正