Oguma Tsuyoshi 小熊剛

… Alternative Names

OGUMA Tsuyoshi 小熊剛

GUMA Tsuyoshi 小熊剛

小熊剛オグマツヨシ

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Researcher Number	20255441
Other IDs
Affiliation (Current)	2025: 東海大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 東海大学, 医学部, 教授 2020 – 2022: 東海大学, 医学部, 准教授 2016: 東海大学, 医学部, 准教授 2014 – 2015: 東海大学, 医学部, 講師 2009 – 2011: 慶應義塾大学, 医学部, 講師 … More 2008: 慶應義塾大学, 医学部, 共同研究員 2007: 慶應義塾大学, 医学部, 助教 1998: 慶應大, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine / Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine
Keywords	Principal Investigator 真菌 / アレルギー性気管支肺アスペルギルス症 / アレルギー性気管支肺真菌症 / IL-1α / アスペルギルス / アレルギー性気道疾患 / 真菌感作喘息 / 真正担子菌 / 難治性気道アレルギー疾患 / 気管支喘息 … More / スエヒロタケ / 光触媒反応 / 真菌アレルゲン / アレルギー性気管支アスペルギルス症 / アレルギー性気管支真菌症 / 酸化チタン / 光触媒 / アレルギー性気管支肺アレルギー症 / プロテアーゼ / セリンプロテアーゼ / ABPM … More Except Principal Investigator CRTH2 / プロスタグランジン / 肺線維症 / 喘息 / 好中球 / 敗血症 / 気管支喘息 / 急性増悪 / 二本鎖RNA / プロスタグランジンD2 / ウイルス感染症 / 呼吸器病学 Less

Exploring Pathophysiological Differences Between Allergic Bronchopulmonary Aspergillosis/Mycoses and Asthma with Fungal SensitizationPrincipal Investigator
- Principal Investigator
  
  小熊剛
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tokai University
Understanding Intractable Fungal Airway Allergy: Pathogenesis and Therapeutic DevelopmentPrincipal Investigator
- Principal Investigator
  
  Oguma Tsuyoshi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tokai University
Identification of novel therapeutic targets for allergic bronchopulmonary mycosisPrincipal Investigator
- Principal Investigator
  
  OGUMA Tsuyoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tokai University
Immunomodulatory role of PGD2/CRTH2 pathway in the pathophysiology of refractory lung diseases
- Principal Investigator
  
  ASANO Koichiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Keio University
Prostaglandin D2 and its receptors in the pathogenesis of refractory inflammatory pulmonary diseases
- Principal Investigator
  
  ASANO Koichiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Keio University
日本人気管支喘息患者におけるケモカイン受容体CCR3遺伝子多型の検討Principal Investigator
- Principal Investigator
  
  小熊剛
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Keio University

All 2024 2022 2021 2017 2016 2015 2014 2011 2010 2009 2008 Other

All Journal Article Presentation Other

[Journal Article] Allergic bronchopulmonary aspergillosis in Japan: a nationwide survey2017
- Author(s)
  Oguma T, Taniguchi M, Shimoda T, Kamei K, Matsuse H, Hebisawa A, Takayanagi N, Konno S, Fukunaga K, Harada K, Tanaka J, Tomomatsu K, and Asano K
- Journal Title
  
  Allergology International
  
  Volume: 印刷中
- NAID
  130006322061
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461167
[Journal Article] アレルギー性気管支肺真菌症（ABPM)の現状と問題点2015
- Author(s)
  小熊　剛
- Journal Title
  
  呼吸
  
  Volume: 34(9) Pages: 149-154
- Data Source
  KAKENHI-PROJECT-26461167
[Journal Article] Phenotype of asthma related with high serum periostin levels2015
- Author(s)
  Matsusaka M, Kabata H, Fukunaga K, Suzuki Y, Masaki K, Mochimaru T, Sakamaki F, Oyamada Y, Inoue T, Oguma T, Sayama K, Koh H, Nakamura M, Umeda A, Ono J, Ohta S, Izuhara K, Asano K, Betsuyaku T.
- Journal Title
  
  Allergol. Int.
  
  Volume: 64 Issue: 2 Pages: 175-180
- DOI
  10.1016/j.alit.2014.07.003
- NAID
  130005290305
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461167, KAKENHI-PROJECT-15K09553, KAKENHI-PROJECT-15K15372, KAKENHI-PROJECT-25461504, KAKENHI-PROJECT-26670420, KAKENHI-PROJECT-25293224
[Journal Article] Dual Role of Interleukin-23 in Epicutaneously-Sensitized Asthma in Mice2014
- Author(s)
  Masaki K, Suzuki Y, Kagawa S, Kodama M, Kabata H, Miyata J, Tanaka K, Fukunaga K, Sayama K, Oguma T, Kimura T, Amagai M, Betsuyaku T, Asano K.
- Journal Title
  
  Allergol. Int.
  
  Volume: 63 Issue: Supplement.1 Pages: S13-S22
- DOI
  10.2332/allergolint.13-OA-0632
- NAID
  130004477229
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461167, KAKENHI-PROJECT-26461198
[Journal Article] Induction of mucin and MUC5AC expression by the protease activity of Aspergillus fumigatus in airway epithelial cells2011
- Author(s)
  T. Oguma, K. Asano, K. Tomomatsu, M. Kodama, K. Fukunaga, T. Shiomi, N. Ohmori, S. Ueda, T. Takihara, Y. Shiraishi, K. Sayama, S. Kagawa, Y. Natori, C. M. Lilly, K. Satoh, K. Makimura, and A. Ishizaka
- Journal Title
  
  J Immunol
  
  Volume: 187(2) Pages: 999-1005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590971
[Journal Article] Role of prostaglandin D2 receptor, CRTH2, in sustained eosinophil accumulation in the airways of mice with chronic asthma2011
- Author(s)
  S. Kagawa, K. Fukunaga, Y. Shiraishi, T. Oguma, Y. Suzuki, T. Shiomi, K. Sayama, N. Kimura, H. Hirai, K. Nagata, M. Nakamura, K. Asano
- Journal Title
  
  Int Arch Allergy Immunol
  
  Volume: 155 Pages: 6-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590971
[Journal Article] Role of prostaglandin D_2 and its receptors in the pathophysiology of asthma2008
- Author(s)
  T. Oguma, K. Asano, and A. Ishizaka
- Journal Title
  
  Allergol Int 57
  
  Pages: 307-312
- NAID
  10025108291
- Data Source
  KAKENHI-PROJECT-19590912
[Journal Article] Role of prostaglandin D_2 and its receptors in the pathophysiology of asthma2008
- Author(s)
  T. Oguma, K. Asano., A. Is hizaka
- Journal Title
  
  Allergol Int 57
  
  Pages: 307-312
- NAID
  10025108291
- Data Source
  KAKENHI-PROJECT-19590912
[Presentation] アレルギー性気管支肺真菌症（ABPM）における粘液栓について2024
- Author(s)
  小熊　剛
- Organizer
  第64回日本呼吸器学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08577
[Presentation] 本邦におけるアスペルギルス感作重症喘息の臨床像の検討2022
- Author(s)
  小熊　剛、他
- Organizer
  日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-20K08577
[Presentation] 新しい臨床診断基準で診断されたアレルギー性気管支肺真菌症（ABPM）のフェノタイプの検討2022
- Author(s)
  小熊　剛、他
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K08577
[Presentation] アレルギー性気管支肺真菌症2021
- Author(s)
  小熊　剛
- Organizer
  第70回日本アレルギー学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08577
[Presentation] 真菌関連アレルギー性気道疾患における真菌感作プロファイルの検討.2021
- Author(s)
  小熊　剛
- Organizer
  第61回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K08577
[Presentation] 真菌関連アレルギー性気道疾患の診断 -血清学的診断を中心に-2021
- Author(s)
  小熊　剛
- Organizer
  第70回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-20K08577
[Presentation] アレルギー性気管支肺真菌症合併重症喘息にオマリズマブを使用した33症例の検討2016
- Author(s)
  友松克允、小熊剛、田中淳、浅野浩一郎、ABPM研究班
- Organizer
  第56回日本呼吸器学会学術講演会
- Place of Presentation
  国立京都国際会館　(京都府京都市)
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-26461167
[Presentation] アレルギー性気管支肺アスペルギルス症症例における血清ペリオスチン濃度の検討2016
- Author(s)
  田中淳, 小熊剛、原田一樹、友松克允、松坂雅子、加畑宏樹、福永興壱、別役智子、小野純也、太田昭一郎、出原賢冶、浅野浩一郎
- Organizer
  第65回日本アレルギー学会学術大会
- Place of Presentation
  東京国際フォーラム　(東京都千代田区)
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-26461167
[Presentation] アレルギー性気管支肺アスペルギルス症症例における血清ペリオスチン濃度の検討2016
- Author(s)
  田中淳、小熊剛、原田一樹、友松克允、松坂雅子、加畑宏樹、福永興壱、別役智子、小野純也、太田昭一郎、出原賢冶、浅野浩一郎
- Organizer
  アレルギー好酸球研究会
- Place of Presentation
  学術総合センター (東京都千代田区)
- Year and Date
  2016-10-22
- Data Source
  KAKENHI-PROJECT-26461167
[Presentation] アレルギー性気管支肺アスペルギルス症におけるアスペルギルス特異的IgG抗体測定法の比較2016
- Author(s)
  原田一樹、小熊剛、福冨友馬、斎藤明美、田中淳、友松克允、下田照文、亀井克彦、松瀬厚人、今野哲、福永興壱、蛇澤晶、高柳昇、谷口正実、浅野浩一郎
- Organizer
  アレルギー好酸球研究会
- Place of Presentation
  学術総合センター　(東京都千代田区)
- Year and Date
  2016-10-22
- Data Source
  KAKENHI-PROJECT-26461167
[Presentation] アレルギー性気管支肺アスペルギルス症におけるアスペルギルス特異的IgG抗体測定法の比較2016
- Author(s)
  原田一樹，小熊剛，友松克允，田中淳，齋藤明美，福冨友馬，谷口正実、下田照文、亀井克彦、松瀬厚人、福永興壱、今野哲、蛇澤晶、高柳昇、浅野浩一郎
- Organizer
  第56回日本呼吸器学会学術講演会
- Place of Presentation
  国立京都国際会館　(京都府京都市)
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-26461167
[Presentation] クラスター解析によるアレルギー性気管支肺アスペルギルス症のPhenotypeの検討2015
- Author(s)
  小熊　剛、友松　克允、下田照文、谷口正実、亀井克彦。松瀬厚人、今野哲、福永興壱、浅野浩一郎
- Organizer
  第55回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京都港区）
- Year and Date
  2015-04-14
- Data Source
  KAKENHI-PROJECT-26461167
[Presentation] シンポジウム10 「ABPA・SAFS」 ABPAの臨床像―全国調査に基づくクラスター解析―2015
- Author(s)
  小熊　剛、田中　淳、友松克允、浅野浩一郎
- Organizer
  第25回国際喘息学会日本・北アジア部会
- Place of Presentation
  ホテルニューグランド（神奈川県横浜市）
- Year and Date
  2015-09-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461167
[Presentation] Identification of Phenotypes in Allergic Bronchopulmonary Aspergillosis Using Cluster Analysis2015
- Author(s)
  T. Oguma, J. Tanaka, K. Tomomatsu, K. Asano
- Organizer
  XXIV World Allergy Congress
- Place of Presentation
  Coex Convention Center (Seoul, Korea)
- Year and Date
  2015-10-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461167
[Presentation] Prostaglandin D_2 receptor, CRTH2, is critical for gamma-delta T cell-mediated suppression of pulmonary inflammation/fibrosis induced by bleomycin2011
- Author(s)
  K Asano, S Ueda, M Ishii, Y Suzuki, K Fukunaga, T Oguma, M Nakamura, K Nagata, H Hirai
- Organizer
  ATS 2011 International Conference
- Place of Presentation
  Denver, USA
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-21590971
[Presentation] PGD2受容体CRTH2を介する肺臓炎・線維化抑制の分子機序2011
- Author(s)
  上田壮一郎, 浅野浩一郎, 加川志津子, 田中希布人、滝原崇久, 福永興壱, 小熊剛, 佐山宏一
- Organizer
  第51回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2011-04-22
- Data Source
  KAKENHI-PROJECT-21590971
[Presentation] Prostaglandin D2 receptor, CRTH2, is critical for gamma-delta T cell-mediated suppression of pulmonary inflammation/fibrosis induced by bleomycin2011
- Author(s)
  K Asano, S Ueda, M Ishii, Y Suzuki, K Fukunaga, T Oguma, M Nakamura, K Nagata, H Hirai
- Organizer
  12th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases
- Place of Presentation
  Seattle, USA
- Year and Date
  2011-09-20
- Data Source
  KAKENHI-PROJECT-21590971
[Presentation] 抗原反復暴露による慢性好酸球性気道炎症におけるプロスタグランジンD_2(PGD_2)受容体CRTH2の意義2010
- Author(s)
  加川志津子、浅野浩一郎、白石良樹、福永興壱、樹神元博、大森奈緒、友松克允、小倉裕美、宮田純、田中希宇人、上石修史、塩見哲也、小熊剛、佐山宏一
- Organizer
  アレルギー好酸球研究会2010
- Place of Presentation
  東京
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-21590971
[Presentation] 慢性喘息モデルにおけるプロスタグランジンD_2(PGD_2)受容体CRTH2の意義2010
- Author(s)
  加川志津子、浅野浩一郎、福永興壱、樹神元博、小川里佳、友松克允、小倉裕美、宮田純、田中希宇人、上石修史、加畑宏樹、塩見哲也、小熊剛、佐山宏一
- Organizer
  第60回日本アレルギー学会総会
- Place of Presentation
  東京
- Year and Date
  2010-11-25
- Data Source
  KAKENHI-PROJECT-21590971
[Presentation] プロスタグランジンD_2受容体CRTH2を介したブレオマイシン肺臓炎の炎症制御機構2009
- Author(s)
  上田壮一郎, 浅野浩一郎, 加川志津子, 田中希布人、滝原崇久, 福永興壱, 小熊剛, 佐山宏一, 石坂彰敏
- Organizer
  第12回間質性肺炎分子病態研究会
- Place of Presentation
  東京
- Year and Date
  2009-08-22
- Data Source
  KAKENHI-PROJECT-21590971
[Presentation] プロスタグランジンD_2受容体CRTH2を介したブレオマイシン肺臓炎の病態修飾2009
- Author(s)
  上田壮一郎, 浅野浩一郎, 白石良樹, 加川志津子, 滝原崇久, 中島剛, 福永興壱, 小熊剛, 佐山宏一, 石坂彰敏
- Organizer
  第49回日本呼吸器学会総会
- Place of Presentation
  東京
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-21590971
[Presentation] Arole of prostaglandin D_2 receptor, CRTH2, on bleomycin-induced pulmonary fibrosis2008
- Author(s)
  S. Ueda, K. Asano, T. Oguma, et al
- Organizer
  European Respiratory Society Annual Congress 2008 Germany
- Place of Presentation
  Berlin
- Year and Date
  2008-10-06
- Data Source
  KAKENHI-PROJECT-19590912
[Presentation] アレルギー性気管支肺真菌症（ABPM）全国調査中間報告
- Author(s)
  小熊　剛
- Organizer
  日本アレルギー学会春季臨床大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-05-09 – 2014-05-11
- Invited
- Data Source
  KAKENHI-PROJECT-26461167
[]

1. ASANO Koichiro (60192944)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. FUKUNAGA Koichi (60327517)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results

Oguma Tsuyoshi 小熊 剛

OGUMA Tsuyoshi 小熊 剛

GUMA Tsuyoshi 小熊 剛

小熊 剛 オグマ ツヨシ

Research Projects

Research Products

Co-Researchers

Exploring Pathophysiological Differences Between Allergic Bronchopulmonary Aspergillosis/Mycoses and Asthma with Fungal SensitizationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding Intractable Fungal Airway Allergy: Pathogenesis and Therapeutic DevelopmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of novel therapeutic targets for allergic bronchopulmonary mycosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunomodulatory role of PGD2/CRTH2 pathway in the pathophysiology of refractory lung diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prostaglandin D2 and its receptors in the pathogenesis of refractory inflammatory pulmonary diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

日本人気管支喘息患者におけるケモカイン受容体CCR3遺伝子多型の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Allergic bronchopulmonary aspergillosis in Japan: a nationwide survey2017

Author(s)

Journal Title

NAID

Data Source

[Journal Article] アレルギー性気管支肺真菌症（ABPM)の現状と問題点2015

Author(s)

Journal Title

Data Source

[Journal Article] Phenotype of asthma related with high serum periostin levels2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Dual Role of Interleukin-23 in Epicutaneously-Sensitized Asthma in Mice2014

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Induction of mucin and MUC5AC expression by the protease activity of Aspergillus fumigatus in airway epithelial cells2011

Author(s)

Journal Title

Data Source

[Journal Article] Role of prostaglandin D2 receptor, CRTH2, in sustained eosinophil accumulation in the airways of mice with chronic asthma2011

Author(s)

Journal Title

Data Source

[Journal Article] Role of prostaglandin D_2 and its receptors in the pathophysiology of asthma2008

Author(s)

Journal Title

NAID

Oguma Tsuyoshi 小熊剛

OGUMA Tsuyoshi 小熊剛

GUMA Tsuyoshi 小熊剛

小熊剛オグマツヨシ

[Presentation] アレルギー性気管支肺真菌症（ABPM）における粘液栓について2024