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SHIBAHARA Kei-ichi  柴原 慶一

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… Alternative Names

柴原 慶一  シバハラ ケイイチ

SHIBAHARA Keiichi  柴原 慶一

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Researcher Number 20263098
Affiliation (based on the past Project Information) *help 2012: 国立遺伝学研究所, 総合遺伝研究系, 准教授
2009: 国立遺伝学研究所, 総合遺伝研究系, 准教授
2008: 国立遺伝学研究所, 総合遺伝研究系, 凖教授
2006: National Institute of Genetics, Assistant Professor
2002 – 2006: 国立遺伝学研究所, 総合遺伝研究系, 助教授 … More
2003: 国立遺伝学研究所, 総合遺伝研究系・育種遺伝研究部門, 助教授
2002: 京都大学, ウイルス研究所, 客員助教授
1994: Faculty of Medicine Medical Chemistry, Kyoto University assistant, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / General medical chemistry / General medical chemistry
Except Principal Investigator
Biological Sciences
Keywords
Principal Investigator
CAF-1 / DNA複製 / DDM1 / ヌクレオソーム / ヌクレオソームアセンブリー / ヒストン / クロマチン / epigenetics / chromatin replication / DNA replication … More / nucleosome / chromatin / モノユビキチン化 / 細胞記憶 / ジーンターゲティング / クロマチン複製 / ジーンサイレンシング / モノユビキチン / fas / macroH2A / ヘテロクロマチン / ヒストン修飾 / リモデリング因子 / DNAメチル化 / ヘテロマクチン / non-coding RNA / エピジェネティクス / チェックポイント … More
Except Principal Investigator
RBP-Jk / ヒストン / クロマチン / ヘテロクロマチン / flowering / genome / imprinting / chromatin / Arabidopsis / DNA methylation / transposon / epigenetic / 胚乳 / ピストン / 染色体 / エピジェネティック / 花成 / ゲノム / インプリンティング / シロイヌナズナ / DNAメチル化 / トランスポゾン / エピジェネティクス / EBNA2 / knock out / programd cell death / ES cells / conculture / PD-1 / クローン欠失 / gene knock-out / 自己免疫 / 計画的細胞死 / Apoptosis / 遺伝子破壊マウス / CD40 / ミニ染色体 / 転写因子 / 情報伝達 / EBウイルス / RBP-Jκ / 細胞死 / クラススイッチ / 血球分化 / 共生細胞 / ES細胞 / 哺乳類 / ヘテロクロマチンタンパク-1(HP1γ) / HP1_γ / ヘテロクロマチ / エピジェネティック制御 / 性染色体不活性化 / 精母細胞 / ポリコーム群 / HP1γ / ヒストンアセチル化 / Tip60 / Epc1 / 対合 / Ring1 / ポリコム群 / ヒストン修飾 / セントロメア / 減数分裂 / 精子形成 / マウス Less
  • Research Projects

    (7 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (11 People)
  •  Epigenetic regulation of mammalian spermatogenesis

    • Principal Investigator
      KOSEKI Haruhiko
    • Project Period (FY)
      2008 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  DDM1によるヘテロクロマチン形成にRNA分子が関与する可能性Principal Investigator

    • Principal Investigator
      柴原 慶一
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute of Genetics
  •  Chromatin replication through cellular proliferation in eukaryotic cellsPrincipal Investigator

    • Principal Investigator
      SHIBAHARA Kei-ichi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      National Institute of Genetics
  •  DNA複製に伴うクロマチン構築機構の解明と発がんとの関連Principal Investigator

    • Principal Investigator
      柴原 慶一
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute of Genetics
  •  DNA複製に伴うクロマチン構築機構及びその生命システムにおける意義の解明Principal Investigator

    • Principal Investigator
      柴原 慶一
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
  •  Epigenetic controls of plant development and genome structure

    • Principal Investigator
      KAKUTANI Tetsuji
    • Project Period (FY)
      2002 – 2006
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      National Institute of Genetics
  •  Mechanisn of lymphocyte differentiation, molecular mechanisms of gene rearrangement and clonal deletion by antigenes

    • Principal Investigator
      HONJO Tasuku
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Research Institution
      KYOTO UNIVERSITY

All 2007 2006 2005 2004

All Journal Article Book Patent

  • [Book] DNA複製・DNA修復がわかる「DNA修復とヌクレオチド除去修復2004

    • Author(s)
      久保知大, 柴原慶一
    • Publisher
      羊土社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390085
  • [Journal Article] Chromatin assembly is required for rapid nucleosome formation during DNA replication and efficient Chk1 activation in vertebrate chicken DT40 cells.2007

    • Author(s)
      Takami, Y., Ono, T., Fukagawa, T., K-i, Shibahara, T.Nakayama.
    • Journal Title

      Mol. Biol. Cell. 18(1)

      Pages: 129-141

    • Data Source
      KAKENHI-PROJECT-16390085
  • [Journal Article] Nuclear RanGAP is required for the heterochromatin assembly and is reciprocally regulated by histone H3 and Clr4 histone methyltransferase in Schizosaccharomyces pombe.2006

    • Author(s)
      Nishijima, H., Nakayama, JI., Yoshioka, T., Kusano, A., Nishitani, H., Shibahara, K-i., Nishimoto, T.
    • Journal Title

      Mol. Biol. Cell 17

      Pages: 2524-2536

    • Data Source
      KAKENHI-PROJECT-16390085
  • [Journal Article] Histone acetyltransferase I is dispensable for replication-coupled chromatin assembly but contributes to recover DNA damages created following replication blockage in vertebrate cells.2006

    • Author(s)
      Barman, HK., Takami, Y., Ono T., Nishijima, H., Sanematsu, F., Shibahara, K-i., Nakayama, T.
    • Journal Title

      Biochem Biophys Res Commun 345

      Pages: 1547-1557

    • Data Source
      KAKENHI-PROJECT-17026036
  • [Journal Article] Enhanced homologous recombination and T-DNA integration in chromatin assemble factor-1 mutants in Arabidopsis thaliana.2006

    • Author(s)
      Endo, M, Ishikawa, Y, Kaya, H, Araki, T, Shibahara, K-i, Ito, Y, Osakabe, K, Abe, K, Ichikawa, H, Valentine, L, Hohn, B, Toki, S.
    • Journal Title

      EMBO J. 25(23)

      Pages: 5579-5590

    • Data Source
      KAKENHI-PROJECT-16390085
  • [Journal Article] Nuclear RanGAP is required for the heterochromatin assembly and is reciprocally regulated by histone H3 and Clr4 histone methyltransferase in Schizosaccharomyces pombe.2006

    • Author(s)
      Nishijima, H., Nakayama, JI., Yoshioka, T., Kusano, A., Nishitani, H., Shibahara, K-i., Nishimoto, T.
    • Journal Title

      Mol. Biol. Cell 17

      Pages: 2524-2536

    • Data Source
      KAKENHI-PROJECT-17026036
  • [Journal Article] Simple, one-week method to construct gene-targeting vectors : application to production of human knockout cell lines.2006

    • Author(s)
      Iizzumi., S, Nomura, Y., So, S., Uegaki, K., Aoki, K., Shibahara K-i., Adachi, N., Koyama H.
    • Journal Title

      Bio Techniques 41(3)

      Pages: 311-316

    • Data Source
      KAKENHI-PROJECT-16390085
  • [Journal Article] Chromatin assembly factor 1 ensures the stable maintenance of silent chromatin states in Arabidopsis.2006

    • Author(s)
      Ono, T., Kaya, H., Takeda, S., Abe, Y., Ogawa, Y., Kato, M., Kakutani, T., Scheid, OM., Araki, T., Shibahara, K-i
    • Journal Title

      Genes Cells (Covert to this issue) 18

      Pages: 153-162

    • Data Source
      KAKENHI-PROJECT-16390085
  • [Journal Article] Enhanced homologous recombination and T-DNA integration in chromatin assembly factor-1 mutants in Arabidopsis thaliana.2006

    • Author(s)
      Endo, M., Ishikawa, Y., Kaya, H., Araki, T., Shibahara, K-i., Ito, Y., Osakabe, K., Abe, K., Ichikawa, H., Valentine, L., Hohn, B., Toki, S.
    • Journal Title

      EMBO J. 25(23)

      Pages: 5579-5590

    • Data Source
      KAKENHI-PROJECT-17026036
  • [Journal Article] Asfl is required for viability and chromatin assembly during DNA replication in vertebrate cells.2006

    • Author(s)
      Sanematsu, F., Takami, Y., Barman, HK., Fukagawa, T., Ono, T., Shibahara, K-i, Nakayama T.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 13817-13827

    • Data Source
      KAKENHI-PROJECT-17026036
  • [Journal Article] Asfl is required for viability and chromatin assembly during DNA replication in vertebrate cells.2006

    • Author(s)
      Sanematsu, F., Takami, Y., Barman, HK., Fukagawa, T., Ono, T., Shibahara, K-i., Nakayama T.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 13817-13827

    • Data Source
      KAKENHI-PROJECT-16390085
  • [Journal Article] Chromatin assembly factor I ensures the stable maintenance of silent chromatin states in Arabidopsis.2006

    • Author(s)
      Ono, T., Kaya, H., Takeda, S., Abe, Y., Ogawa, Y., Kato, M., Kakutani, T., Scheid.OM, Araki, T., Shibahara, K-i
    • Journal Title

      Genes Cells (Cover to this issue) 18

      Pages: 153-162

    • Data Source
      KAKENHI-PROJECT-17026036
  • [Journal Article] Histone acetyltransfcrase 1 is dispensable for replication-coupled chromatin assembly but contributes to recover DNA damages created following replication blockage in vertebrate cells.2006

    • Author(s)
      Barman, HK., Takami Y., Ono T., Nishijima, H., Sanematsu, F., Shibahara, K-i., Nakayama, T.
    • Journal Title

      Biochem Biophys Res Commun 345

      Pages: 1547-1557

    • Data Source
      KAKENHI-PROJECT-16390085
  • [Journal Article] Chromatin assembly factor-1 is required for rapid nucleosome formation during DNA replication and efficient Chkl activation in vertebrate chicken DT40 cells.2006

    • Author(s)
      Takami, Y., Ono, T., Fukagawa, T., K-i.Shibahara, T.Nakayama
    • Journal Title

      Mol. Biol. Cell. 18(1)

      Pages: 129-141

    • Data Source
      KAKENHI-PROJECT-17026036
  • [Patent] 標的組換え細胞とランダム組換え細胞を判別する方法およびその用途2007

    • Inventor(s)
      柴原慶一, 西嶋仁, 国田嘉元
    • Industrial Property Rights Holder
      情報・システム研究機構
    • Industrial Property Number
      2007-011971
    • Filing Date
      2007-04-27
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390085
  • [Patent] デトラサイクリン誘導体の遺伝子発現系に使用する目的遺伝子導入ベクター、トランスアクチベーター発現用ベクターおよびその用途2006

    • Inventor(s)
      柴原慶一, 小野達也
    • Industrial Property Number
      2006-288020
    • Filing Date
      2006-10-23
    • Data Source
      KAKENHI-PROJECT-16390085
  • [Patent] テトラサイクリン誘導型の遺伝子発現系に使用する目的遺伝子導入ベクター、トランスアクチベーター発現用ベクターおよびその用途2006

    • Inventor(s)
      柴原慶一, 小野達也
    • Industrial Property Rights Holder
      情報・システム研究機構
    • Industrial Property Number
      2006-288020
    • Filing Date
      2006-10-23
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390085
  • [Patent] 標的組換え細胞とランダム組換え細胞を判別する方法及びその用途2006

    • Inventor(s)
      柴原慶一, 西嶋 仁, 国田嘉元
    • Industrial Property Number
      2007-011971
    • Filing Date
      2006-04-27
    • Data Source
      KAKENHI-PROJECT-17026036
  • [Patent] テトラサイクリン誘導型の遺伝子発現系に使用する目的遺伝子導入ベクター、トランスアクチベーター発現用ベクターおよびその用途2006

    • Inventor(s)
      柴原慶一, 小野達也
    • Industrial Property Number
      2006-288020
    • Filing Date
      2006-10-23
    • Data Source
      KAKENHI-PROJECT-17026036
  • [Patent] 標的組換え細胞とランダム組換え細胞を判別する方法およびその用途2006

    • Inventor(s)
      柴原慶一, 西嶋仁, 国田嘉元
    • Industrial Property Number
      2007-011971
    • Filing Date
      2006-04-27
    • Data Source
      KAKENHI-PROJECT-16390085
  • [Patent] 遺伝子導入方法、ジーンターゲッティング方法及びトランスジェニック植物の製造方法2005

    • Inventor(s)
      柴原 慶一
    • Industrial Property Rights Holder
      柴原 慶一
    • Industrial Property Number
      2005-065442
    • Filing Date
      2005-03-09
    • Data Source
      KAKENHI-PROJECT-16390085
  • [Patent] 遺伝子導入方法、ジーンターゲッティング方法及びトランスジェニック植物の製造方法2005

    • Inventor(s)
      柴原慶一
    • Industrial Property Rights Holder
      情報・システム研究機構
    • Industrial Property Number
      2005-006544
    • Filing Date
      2005-03-09
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390085
  • 1.  NISHIJIMA Hitoshi (60425410)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 2.  ONO Tatsuya (50419850)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 3.  KOSEKI Haruhiko (40225446)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  TAKADA Yuki (40392013)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  HONJO Tasuku (80090504)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KAKUTANI Tetsuji (20332174)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  KINOSHITA Tetsu (60342630)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  ARAKI Takashi (00273433)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  OGAWA Yuya (10370123)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  石田 靖雅 (10221756)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  鍔田 武志 (80197756)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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