KASHIWADA MASAKI 柏田正樹

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KASIWADA Masaki 柏田正樹

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Researcher Number	20270639
Other IDs
Affiliation (based on the past Project Information) *help	2016: 自治医科大学, 医学部, 客員研究員 2012 – 2015: 自治医科大学, 医学部, 准教授 1997: 感染研, 研究員 1994 – 1996: 国立予防衛生研究所, 免疫部, 研究員
Review Section/Research Field	Principal Investigator Biological pharmacy / Immunology Except Principal Investigator Immunology
Keywords	Principal Investigator 時計遺伝子 / アレルギー性疾患 / 樹状細胞 / 概日リズム / Th2 / アナフィラキシー / 肥満細胞 / 喘息 / アレルギー Except Principal Investigator CD40 … More / antigen presentation / somatic hypermutation / cell cycle / germinal center / TRAF / MAP kinase / primary follicles / 免疫グロブリン遺伝子 / 記憶Bリンパ球 / centrocyte / Bリンパ球 / 体細胞点変異 / centroblast / 一次免疫反応 / 細胞周期 / 抗原提示機能 / 高親和性B細胞 / 体細胞超変異 / 細胞増殖 / 胚中心 / MAPキナーゼ / 一次濾胞B細胞 / mice lacking Vpre-B3 (8HS-20) gene / surrogate loght chain / gene targeting / T dependent antigen / Vper-B1 / lambda 5 / mu chain complex / B cell differentiation / 脾臓 / 骨髄 / FACS / 免疫応答 / 分化 / 遺伝子ターゲッティング / pre B細胞 / T依存性免疫応答 / 細胞分化 / Dμ蛋白 / Vpre-B3 / B細胞 / Vpre-B3欠損マウス / 代替L鎖 / 遺伝子欠損マウス / T依存性抗原 / Vpre-B1 / λ5 / μ鎖複合体 / B細胞分化 Less

概日時計遺伝子によるアレルギー性疾患の病態制御機構の解明Principal Investigator
- Principal Investigator
  
  柏田正樹
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Jichi Medical University
Study on roles of circadian clock gene in allergic immune responsePrincipal Investigator
- Principal Investigator
  
  KASHIWADA MASAKI
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Jichi Medical University
CD40によるB細胞の増殖・細胞死抑制に関わるシグナル伝達経路の解明Principal Investigator
- Principal Investigator
  
  柏田正樹
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  国立予防衛生研究所
Mechanism of B cell maturaion
- Principal Investigator
  
  TAKEMORI Toshitada
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  National Institute of Health
Analysis of mutant mice lacking Vpre-B3 (8HS-20) gene encoding a third surrogate light chair.
- Principal Investigator
  
  KIMOTO Hiroshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  National Institute of Health ofJapan

All 2014 2013 2012

All Journal Article Presentation

[Journal Article] NFIL3-Deficient Mice Develop Microbiota-Dependent, IL-12/23-Driven Spontaneous Colitis.2014
- Author(s)
  Kobayashi, T., Steinbach, E.C., Russo, S.M., Matsuoka, K., Nochi, T., Maharshak, N., Borst, L.B., Hostager, B., Garcia-Martinez, J.V., Rothman, P.B., Kashiwada, M., Sheikh, S.Z., Murray, P.J. and Plevy, S.E.
- Journal Title
  
  Journal of Immunology
  
  Volume: 192 Issue: 4 Pages: 1918-1927
- DOI
  10.4049/jimmunol.1301819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590088, KAKENHI-PROJECT-25460960
[Journal Article] TH17 cell differentiation is regulated by the circadian clock.2013
- Author(s)
  Yu, X., Rollins, D., Ruhn, K.A., Stubblefield, J.J., Green, C.B., Kashiwada, M., Rothman, P.B., Takahashi, J.S., and Hooper, L.V.
- Journal Title
  
  Science
  
  Volume: 342 Issue: 6159 Pages: 727-730
- DOI
  10.1126/science.1243884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590088
[Journal Article] A requirement for SOCS-1 and SOCS-3 phosphorylation in Bcr-Abl-induced tumorigenesis2012
- Author(s)
  Xiaoxue Qiu, Guijie Guo, Ke Chen, Masaki Kashiwada, Brian Druker, Paul Rothman and Jilong Chen
- Journal Title
  
  Neoplasia
  
  Volume: 14 Issue: 6 Pages: 547-558
- DOI
  10.1596/neo.12230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590088
[Presentation] サイトカイン誘導性転写因子NFIL3/E4BP4によるTh2反応制御2013
- Author(s)
  柏田正樹、Suzanne Cassel, John Colgan, Paul Rothman
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24590088
[Presentation] NFIL3 suppresses Rorγt transcription and links intestinal Th17 cell differentiation to the circadian clock network.2013
- Author(s)
  1) Yu, X., Rollins, D., Kashiwada, M., Rothman, P., Takahashi, J. and Hooper, L.
- Organizer
  IMMUNOLOGY 2013
- Place of Presentation
  Honolulu, USA
- Data Source
  KAKENHI-PROJECT-24590088
[Presentation] NFIL3 suppresses Rorγt transcription and links intestinal Th17 cell differentiation to the circadian clock network.2013
- Author(s)
  2) Yu, X., Rollins, D., Kashiwada, M., Rothman, P., Takahashi, J. and Hooper, L.
- Organizer
  78th Cold Spring Harbor Symposium on Quantitative Biology; Immunity & Tolerance.
- Place of Presentation
  Cold Spring Harbor Laboratory, New York, USA
- Data Source
  KAKENHI-PROJECT-24590088
[Presentation] NFIL3 deficient mice develop IL-12/23 driven spontaneous colitis.2013
- Author(s)
  3) Kobayashi, T., Russo, S.M., Matsuoka, K., Nochi, T., Maharshak, N., Borst, L.B., Hostager, B., Garcia-Martinez, J.V., Rothman, P.B., Kashiwada, M., Murray, P.J., Plevy, S.E.
- Organizer
  1st Annual Meeting of Asian Organization for Crohn’s & Colitis
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590088
[Presentation] Lineage-specific regulation of natural killer cell development and function by the transcription factor NFIL3/E4BP42012
- Author(s)
  Kashiwada, M., Heusel, J.W. and Rothman, P.B.
- Organizer
  Cold Spring Harbor Laboratory Meeting; Gene Expression and Signaling in the Immune System
- Place of Presentation
  Cold Spring Harbor Laboratory (New York)
- Data Source
  KAKENHI-PROJECT-24590088
[Presentation] NFIL3 deficient mice develop severe innate immune mediated spontaneous colitis2012
- Author(s)
  Kobayashi, T., Russo, S., Matsuoka, K. Nochi, T., Borst, L.B., Garcia, J.V., Rothman, P.B., Kashiwada, M. and Plevy, S.E.
- Organizer
  Digestive Disease Week (DDW) 2012
- Place of Presentation
  San Diego Convention Center (San Diego)
- Data Source
  KAKENHI-PROJECT-24590088

1. KIMOTO Hiroshi (20225080)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. TAKEMORI Toshitada (60114295)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. ADACHI Yoshihiro (20291122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NAGAOKA Hitoshi (20270647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KASHIWADA MASAKI 柏田 正樹

KASIWADA Masaki 柏田 正樹

Research Projects

Research Products

Co-Researchers

概日時計遺伝子によるアレルギー性疾患の病態制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on roles of circadian clock gene in allergic immune responsePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CD40によるB細胞の増殖・細胞死抑制に関わるシグナル伝達経路の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of B cell maturaion

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of mutant mice lacking Vpre-B3 (8HS-20) gene encoding a third surrogate light chair.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] NFIL3-Deficient Mice Develop Microbiota-Dependent, IL-12/23-Driven Spontaneous Colitis.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TH17 cell differentiation is regulated by the circadian clock.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A requirement for SOCS-1 and SOCS-3 phosphorylation in Bcr-Abl-induced tumorigenesis2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] サイトカイン誘導性転写因子NFIL3/E4BP4によるTh2反応制御2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] NFIL3 suppresses Rorγt transcription and links intestinal Th17 cell differentiation to the circadian clock network.2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] NFIL3 suppresses Rorγt transcription and links intestinal Th17 cell differentiation to the circadian clock network.2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] NFIL3 deficient mice develop IL-12/23 driven spontaneous colitis.2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Lineage-specific regulation of natural killer cell development and function by the transcription factor NFIL3/E4BP42012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] NFIL3 deficient mice develop severe innate immune mediated spontaneous colitis2012

Author(s)

Organizer

Place of Presentation

Data Source

KASHIWADA MASAKI 柏田正樹

KASIWADA Masaki 柏田正樹