Sugihara kazumi 杉原数美

… Alternative Names

SUGIHARA Kazumi 杉原数美

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Researcher Number	20271067
Other IDs
External Links
Affiliation (Current)	2025: 広島国際大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2025: 広島国際大学, 薬学部, 教授 2012 – 2023: 広島国際大学, 薬学部, 教授 2012: 広島国際大学, 薬学部 2009 – 2011: Hiroshima International University, 薬学部, 准教授 2010: 広島大学, 医歯薬総合研究科, 准教授 … More 2008: Hiroshima University, 医歯薬学総合研究科, 准教授 2007: Hiroshima University, Graduate School of Biomedical Sciences, Assistant Professor 2006: 広島大学, 大学院理学研究か, 助教 2006: Hiroshima University, Faculty of Pharmacy, Teaching Associate, 薬学部, 教務員 1998 – 2005: 広島大学, 医学部, 教務員 Less
Review Section/Research Field	Principal Investigator Environmental pharmacy / Basic Section 63030:Chemical substance influence on environment-related / Environmental and hygienic pharmacy Except Principal Investigator Environmental pharmacy / Medical pharmacy / Basic Section 47060:Clinical pharmacy-related / Environmental pharmacy / Neurochemistry/Neuropharmacology / 医薬分子機能学 / Risk sciences of radiation and chemicals / Risk sciences of radiation/Chemicals / Drug development chemistry / Science and Engineering
Keywords	Principal Investigator 医薬品 / 環境汚染 / 生態毒性 / 内分泌かく乱 / 植物 / 環境中医薬品類(PPCPs) / 植物成長影響 / 植物ホルモン様作用 / 植物ホルモン / 環境中医薬品類（PPCPｓ） … More / エピジェネティクス / アルデヒドオキシダーゼ / シトクロムP450 / 系統差 / ホルモン / 転写制御 / 薬毒物代謝酵素 / 内分泌かく乱物質 / 成長ホルモン / 薬物代謝酵素 / 性差 / Effect to ecosystem / Hospital sewage / Environmental pollution / Pharmaceuticals / 生態影響 / 下水処理 / 病院下水 / Glucocorticoid / Endocrine disrupters / Adrenal cortex hormone / Dioxin / 糖質コルチコイド / 内分泌撹乱化学物質 / 副腎皮質ホルモン / ダイオキシン / 環境保全リーダー育成 / 環境動態 / 生態系毒性 / 大韓民国 / 医薬品汚染 / 東アジア / 変異原性 / 環境因子 / 紫外線 / 太陽光 … More Except Principal Investigator 代謝的活性化 / テトラヒドロイソキノリン / パーキンソン病 / Parkinson's disease / ブロム化難燃剤 / 神経毒 / tetrahydroisoquinoline / 甲状腺ホルモン / パーキンソニズム / Metabolic activation / Endocrine disruptor / ドーパミン神経 / パーキンソン病発症物質 / 薬物代謝酵素 / 内分泌撹乱作用 / 核内受容体 / 水酸化代謝物 / 内分泌撹乱 / 内分泌撹乱物質 / xanthine oxidase / 内分泌撹乱活性 / parkinsonism / Brominated flame retardant / Tetrabromobisphenol A / Thyroid hormonal activity / 変態 / オタマジャクシ / P-glycoprotein / 1MeTIQ / Environmental pollutant / neurotoxin / ビテロゲニン / エストロゲン / 内分泌撹乱前駆物質 / Parkinson's disease causing substance / 細胞培養 / パーキンソン病防御物質 / 禁煙治療 / ニコチン製剤 / 医療薬学 / 薬学 / 甲状腺ホルモン撹乱 / カリブ諸島 / P糖タンパク質 / テトラハイドロイソキノリン / oral mucositis / circadian rhythm / uric acid / キサンチンオキシダーゼ / 高尿酸血症 / 尿酸 / xanthine oxidoreductase / 日内変動 / キサンチンオキシドレダクターゼ / 代謝酵素 / 投与設計 / nicotine製剤 / 殺菌料パラベン / 代謝活性化 / 残留性農薬 / 殺菌剤パラベン / リン系難燃剤 / 紫外線吸収剤 / 生活関連化学物質 / シトクロムP450 / 生活用品 / 環境化学物質 / Amphibian metamorphosis / Estrogenic activity / Polybromodiphenyl ether / ポリブロモジフェニールエーテル / 両生類 / 甲状腺ホルモン活性 / 臭素化難燃剤 / Caribbean islands / Annonaceae / サワーソップ / prodrug / neurotxin / プロドラッグ / P糖蛋白質 / Tadpole tail regression / Hydroxylated PCB / アンタゴニスト / テチラbyリノブスフェノールA / 甲状腺ホルモン様作用 / アゴニスト作用 / 水酸化PCB / expression level / drug transporter / tetrahydroisoguinoline / テトラヒドロイソキノリン酸 / 遺伝子発現調節 / テトラヒドロイソキノリン類 / structure-activity relationship / anti-parkinsonian drug / tetrahydroisogunoline / 細胞培養系 / ミトコンドリア呼吸鎖阻害 / 1ベンジルTIQ / 代謝変換 / サルゾリノール / Drug metabolizing enzyme / Vitellogenin / Thyroid hormonal compound / Antiandrogen / Estrogen / 甲状腺ホルモン撹乱物質 / 環境汚染物質 / 甲状腺ホルモン様物質 / 抗アンドロゲン / cDNA microaray / apoptosis / differential display / アポトーシス / NMDAレセプター / アポトーシス関連遺伝子 / cDNAマイクロアレイ / ディファレンシャルディスプレイ / drug metabolizing enzyme / biphenyl / trans-stilbene / vitellogenin / metabolic activation / estrogen / proestrogen / endocrine disruptor / トランスースチルベンオキシド / トランス-スチルベン / ビフェニール / トランスースチルベン / aldehydeoxidase / early marker / アルデヒドオキシダーゼ / アルデヒドオキシターゼ / 早期診断技術 / cell culture / dopaminergic neuron / Parkinson's disease cpreventing substance / 環境汚染 / 錠剤粉砕 / 帯電量 / 散剤調剤 / 後発医薬品 / 医薬品粉じん / 医薬品曝露 / 医薬品汚染 / ニコチン / CYP2A6 / aldehyde oxidase / nicotine / 甲状腺ホルモン受容体 / 甲状腺ホルモン代謝 / PCB / 薬物代謝 / 薬物動態 / リスク評価 / 化学物質 / ヒト肝細胞移植キメラマウス / プロテインジスルフィドイソメラーゼ / 核内レセプター / プロテインジスルフィッドイソメラーゼ / 甲状腺ホメオスタシス / プロム化難燃剤 / 新生児期曝露 / 発達期影響 / 甲状腺ホルモン応答遺伝子 / 子供の環境リスク / 内分泌かく乱物質 / パーキンソン病モデル動物 / アルカロイド / 構造決定 / 天然物化学 / バーキンソン病類縁疾患 / トゲバンレイシ / 地域特異的神経変性疾患 / P糖タンパ / イソキノリンアルカロイド / パーキンソン病関連疾患 / 熱帯風土病 / Parkin / ユビキチン化阻害 / parkin / チューブリン / ユビキチン化 / β-チューブリン / 大豆イソフラボン / アルキルフェノール / 異物(薬物)代謝酵素 / 内分泌攪乱物質 / 2-ニトロフルオレン / フェンチオン / 異物代謝酵素 / プロエストロゲン / 抗アンドロゲン活性 / ベンゾフェノン類 / アルキルフェノール類 / ビスフェノールA / 異物代謝 / エストロゲン活性 Less

キサンチン酸化還元酵素活性による抗がん剤起因性口内炎の重症度予測と予防法の確立
- Principal Investigator
  
  田山剛崇
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Hiroshima International University
Study of the effects of PPCPs on plant growth and construction of screening system for endrine disruptors of plantPrincipal Investigator
- Principal Investigator
  
  杉原数美
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  Hiroshima International University
Control of uric acid by considering the change xanthine oxidase activity with the circadian rhythm
- Principal Investigator
  
  Tayama Yoshitaka
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Hiroshima International University
Epigenetic regulation of sex-specific gene expression and investigation of the effects of environmental chemicals and drugsPrincipal Investigator
- Principal Investigator
  
  sugihara kazumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  Hiroshima International University
Influence of chemicals used in consumer products on endocrine-system via activation of nuclear receptors
- Principal Investigator
  
  Kitamura Shigeyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Nihon Pharmaceutical University
Appropriate administration of nicotine according to the metabolic enzyme activity estimated from the nicotine metabolites in saliva.
- Principal Investigator
  
  Tayama yoshitaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Hiroshima International University
Investigation of the Pharmaceutical pollution in the pharmacy and the health impact assessment of occupational exposure
- Principal Investigator
  
  MAEDA SHIZUKO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Hiroshima International University
Estimation of target proteins of hydroxylated PCB and brominated flame retardants for thyroid hormone disruption and the influence by radiation
- Principal Investigator
  
  Kitamura Shigeyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Nihon Pharmaceutical University
Estimation for the adequate dose of nicotine by using the ratio of the metabolites in urine
- Principal Investigator
  
  Tayama Yoshitaka
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Hiroshima International University
Determination of targets for thyroid hormone disruption by brominated flame retardants
- Principal Investigator
  
  KITAMURA Shigeyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Nihon Pharmaceutical University
Risk assessment of chemicals using chimeric mice with humanized liver
- Principal Investigator
  
  OHTA SHIGERU
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Hiroshima University
Study of PPCPs in Eastern Asian countriesPrincipal Investigator
- Principal Investigator
  
  SUGIHARA Kazumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Hiroshima International University
Pathogenetic mechanism of sporadic Parkinson's disease based on familial Parkinson's disease
- Principal Investigator
  
  OHTA Shigeru
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Hiroshima University
Drug development using novel animal model based on the pathogenesis of Parkinson' s disease-related disorders
- Principal Investigator
  
  OHTA Shigeru
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hiroshima University
Effects of neonatal exposure to thyroid hormone disrupting chemicals in rats
- Principal Investigator
  
  FUJIMOTO Nariaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Hiroshima University
Study of environmental pollution by pharmaceuticals and effect of environmental factors on the toxicity.Principal Investigator
- Principal Investigator
  
  SUGIHARA Kazumi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Hiroshima University
Development of anti-Parkinson's disease drugs using P-glycoprotein knockout mice heated with endogenous neurotoxin.
- Principal Investigator
  
  OHTA Shigeru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hiroshima University
Integrated analysis of environmental and genetic factors against Caribbean parkinsonism
- Principal Investigator
  
  OHTA Shigeru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Hiroshima University
Formation of Hydroxylated Metabolites Responsible for the Toxicity of Brominated Flame Retardants and Thyroid Hormone Disrupting Action
- Principal Investigator
  
  KITAMURA Shigeyuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Nihon Pharmaceutical University
Pharmaceuticals in hospital sewages and their toxicities to ecosystemPrincipal Investigator
- Principal Investigator
  
  SUGIHARA Kazumi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  HIROSHIMA UNIVERSITY
Parkinsonism-inducing mechanism by endogenous multifunctional neurotoxins in the brain
- Principal Investigator
  
  OHTA Shigeru
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  HIROSHIMA UNIVERSITY
Thyroid hormone-disrupting activity of brominated retardants and hydroxylated PCBs
- Principal Investigator
  
  KITAMURA Shigeyuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  HIROSHIMA UNIVERSITY
Development of anti-parkinsonian drug using structure-activity relationship
- Principal Investigator
  
  OHTA Shigeru
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  HIROSHIMA UNIVERSITY
内分泌攪乱物質並びにその前駆物質の代謝変換とホルモン作用の修飾
- Principal Investigator
  
  YOSHIHARA Shinichi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Hiroshima University
Metabolic activation of endocrine-disruptors in animal body
- Principal Investigator
  
  KITAMURA Shigeyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  HIROSHIMA UNIVERSITY
Effect of Dioxin and Endocrine disrupters on Adrenal HormonePrincipal Investigator
- Principal Investigator
  
  SUGIHARA Kazumi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Institution
  Hiroshima University
Research for the Parkinson's disease related proteins using endogenous neurotoxins
- Principal Investigator
  
  OHTA Shigeru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  HIROSHIMA UNIVERSITY
Metabolism and endocrine disrupting action of environmental pollutants
- Principal Investigator
  
  KITAMURA Shigeyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Environmental pharmacy
- Research Institution
  Hiroshima University School of Medicine
Investigation of Parkinson's disease causing substances
- Principal Investigator
  
  OHTA Shigeru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Hiroshima University
Early markers of Parkinson's disease
- Principal Investigator
  
  OHTA Shigeru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Hiroshima University

[Book] Organophocphates as endocrine disruptors' in 'Anticholinesterase Pesticides'2011
- Author(s)
  Kitamura, Shigeyuki; Sugihara, Kazumi; Fujimoto, Nariaki; Yamazaki, Takeshi
- Publisher
  Wiley Edited by Satoh, Tetsuo : Gupta, Ramesh C
- Data Source
  KAKENHI-PROJECT-21406005
[Book] in Anticholinesterase pesticides.(Organophosphates as Endocrine Disruptor)2010
- Author(s)
  Kitamura S., Sugihara K., Fujimoto N., Yamazaki T.
- Total Pages
  14
- Publisher
  Wiley and Sons Ltd
- Data Source
  KAKENHI-PROJECT-20590122
[Book] T. Satoh, R. C. Gupta(ed.) Anticholinesterase Pesticides, John Wiley & Sons, Ltd, Hoboken, NJ2010
- Author(s)
  Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
- Publisher
  Organophosphates asendocrine disruptors In
- Data Source
  KAKENHI-PROJECT-20510065
[Book] Organophosphates as Endocrine Disruptor in Anticholinesterase pesticides2010
- Author(s)
  Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
- Data Source
  KAKENHI-PROJECT-21406005
[Book] Anticholinesterase Pesticides : Organophosphates as Endocrine Disruptors2010
- Author(s)
  Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
- Total Pages
  21
- Publisher
  John Wiley & Sons, Ltd, Hoboken
- Data Source
  KAKENHI-PROJECT-20510065
[Book] Organophosphates as Endocrine Disruptor, in Anticholinesterase pesticides.2010
- Author(s)
  Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
- Total Pages
  14
- Publisher
  Johan Wiley and Sons Ltd.
- Data Source
  KAKENHI-PROJECT-21406005
[Book] Organophosphates as Endocrine Disruptor, in Anticholinesterase pesticides.2010
- Author(s)
  Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
- Total Pages
  14
- Publisher
  Johan Wiley and Sons Ltd.
- Data Source
  KAKENHI-PROJECT-20590122
[Book] Endocrine Disruption in Toxic Responses. In Ballantyne Bryan(ed), the 3rd Edition of General and Applied Toxicology2009
- Author(s)
  Kitamura, Shigeyuki, Sugihara, Kazumi, Nakamura, Kazuo, Yaichiro Kotake, Kashiwagi, Akihiko, Fujimoto, Nariaki
- Total Pages
  15
- Publisher
  Johan Wiley and Sons Ltd
- Data Source
  KAKENHI-PROJECT-20590122
[Book] General and Applied Toxicology III Endocrine Disruption in Toxic Responses2009
- Author(s)
  Kitamura, S., Sugihara, K., Nakamura, K., Kotake, K., Kashiwagi, A., Fujimoto, N.
- Total Pages
  44
- Publisher
  John Wiley & Sons, Ltd, Chichester
- Data Source
  KAKENHI-PROJECT-20510065
[Book] Endocrine Disruption in Toxic Responses, B. Ballantyne, T. Marrs, T. Syversen(ed.) General and AppliedToxicology III, John Wiley & Sons, Ltd, Chichester2009
- Author(s)
  Kitamura, S., Sugihara, K., Nakamura, K., Kotake, K., Kashiwagi, A., Fujimoto, N.
- Data Source
  KAKENHI-PROJECT-20510065
[Book] Endocrine Disruption in Toxic Responses. In Ballantyne Bryan(ed), the 3rd Edition of General and Applied Toxicology2009
- Author(s)
  Kitamura, Shigeyuki ; Sugihara, Kazumi ; Nakamura, Kazuo ; Yaichiro Kotake ; Kashiwagi, Akihiko ; Fujimoto, Nariaki
- Data Source
  KAKENHI-PROJECT-21406005
[Book] Endocrine Disruption in Toxic Responses. In Ballantyne Bryan(ed), the 3rd Edition of General and Applied Toxicology2009
- Author(s)
  Kitamura, Shigeyuki, Sugihara, Kazumi, Nakamura, Kazuo, Yaichiro Kotake, Kashiwagi, Akihiko, Fujimoto, Nariaki
- Total Pages
  15
- Publisher
  Johan Wiley and Sons Ltd
- Data Source
  KAKENHI-PROJECT-21406005
[Book] THYROID HORMONAL AND ESTROGENIC ACTIVITIES OF HYDROXYLATED PCB AND BROMINATED FLAME RETARDANT IN CELL CULTURE, JME2008
- Author(s)
  Kitamura Shigeyuki, Sugihara, Kazumi, et al.
- Publisher
  POPS in Asia
- Data Source
  KAKENHI-PROJECT-20590122
[Book] SCREENING OF AhR-BINDING, ESTROGENIC AND ANTIANDROGENIC ACTIVITIES OF BENZOPHENONE DERIVATIVES USED AS UV STABILIZERS AND SUNSCREENS.2008
- Author(s)
  Sugihara Kazumi
- Publisher
  POPs in Asia
- Data Source
  KAKENHI-PROJECT-20590122
[Book] SCREENING OF AhR-BINDING, ESTROGENIC AND ANTIANDROGENIC ACTIVITIES OF BENZOPHENONE DERIVATIVES USED AS UV STABILIZERS AND SUNSCREENS2008
- Author(s)
  Sugihara, Kazumi, et al.
- Publisher
  JME, POPs in Asia
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Xanthine oxidase and aldehyde oxidase contribute to allopurinol metabolism in rats2022
- Author(s)
  Yoshitaka Tayama, Kazumi Sugihara, Seigo Sanoh, Katsushi Miyake, Shigeyuki Kitamura, Shigeru Ohta
- Journal Title
  
  J Pharm Health Care Sci.
  
  Volume: 8 Issue: 1
- DOI
  10.1186/s40780-022-00262-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07182
[Journal Article] Profiling of bisphenol A and eight its analogues on transcriptional activity via human nuclear receptors2019
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Seigo Sanoh, Katsuhiro Okuda, Shigeyuki Kitamura, Naoto Uramaru, Kazumi Sugihara, Kouichi Yoshinari
- Journal Title
  
  Toxicology, 413(2),48-55,
  
  Volume: 413 Pages: 48-55
- DOI
  10.1016/j.tox.2018.12.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08401, KAKENHI-PROJECT-17K15493, KAKENHI-PROJECT-18H03035, KAKENHI-PROJECT-16K00559
[Journal Article] Inhibitory effects of drugs on the metabolic activity of mouse and human aldehyde oxidases and influence on drug-drug interactions2018
- Author(s)
  Naoki Takaoka; Seigo Sanoh; Katsuhiro Okuda; Yaichiro Kotake; Go Sugahara; Ami Yanagi; Yuji Ishida; Chise Tateno;Yoshitaka Tayama; Kazumi Sugihara; Shigeyuki Kitamura; Mami Kurosaki; Mineko Terao; Enrico Garattini; Shigeru Ohta
- Journal Title
  
  Biochem. Pharmacol., 154, 28-38. 2018
  
  Volume: 154 Pages: 28-38
- DOI
  10.1016/j.bcp.2018.04.017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08401, KAKENHI-PROJECT-16K00559
[Journal Article] Effect of Environmental Factors on the Ecotoxicity of Pharmaceuticals and Personal Care Products2018
- Author(s)
  Kazumi Sugihara
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 138 Issue: 3 Pages: 277-280
- DOI
  10.1248/yakushi.17-00177-2
- NAID
  130006410646
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-03-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08401
[Journal Article] Inhibitory effects of drugs on the metabolic activity of mouse and human aldehyde oxidases and influence on drug-drug interactions2018
- Author(s)
  Naoki Takaoka; Seigo Sanoh; Katsuhiro Okuda;Yaichiro Kotake; Go Sugahara; Ami Yanagi; Yuji Ishida; Chise Tateno;Yoshitaka Tayama; Kazumi Sugihara; Shigeyuki Kitamura; Mami Kurosaki; Mineko Terao; Enrico Garattini; Shigeru Ohta
- Journal Title
  
  Biochem. Pharmacol.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08401
[Journal Article] Comparative study of hydrolytic metabolism of dimethyl phthalate, dibutyl phthalate and di(2-ethylhexyl) phthalate by microsomes of various rat tissues2017
- Author(s)
  Ozaki H., Sugihara K., Watanabe Y., Moriguchi K., Uramaru N., Sone T., Ohta S., Kitamura S.
- Journal Title
  
  Food and Chemical Toxicology
  
  Volume: 100 Pages: 217-224
- DOI
  10.1016/j.fct.2016.12.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00559, KAKENHI-PROJECT-17K08401
[Journal Article] Developmental changes in drug-metabolizing enzyme expression during metamorphosis of Xenopus tropicalis 2017
- Author(s)
 Mori J., Sanoh S., Kashiwagi K., Hanada H., Shigeta M., Suzuki K., Yamamoto T., Kotake Y., Sugihara K., Kitamura S., Kashiwagi A., Ohta S.
- Journal Title
 
 The Journal of Toxicological Sciences
 
 Volume: 42 Issue: 5 Pages: 605-613
- DOI
 10.2131/jts.42.605
- NAID
 130006076698
- ISSN
 0388-1350, 1880-3989
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-16K00559, KAKENHI-PROJECT-17K08401, KAKENHI-PROJECT-17J02822
[Journal Article] In vitro metabolism of methiocarb and carbaryl in rats, and its effect on their estrogenic and antiandrogenic activities.2016
- Author(s)
  Tange S., Fujimoto N., Uramaru N., Wong F. F., Sugihara K., Ohta S., Kitamura S.
- Journal Title
  
  Environ Toxicol Pharmacol
  
  Volume: 41 Pages: 289-297
- DOI
  10.1016/j.etap.2015.08.014
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25340049, KAKENHI-PROJECT-16K00559
[Journal Article] Cytochrome P450-inhibitory activity of parabens and phthalates used in consumer products2016
- Author(s)
  Hitomi Ozaki, Kazumi Sugihara, Yoko Watanabe, Shigeru Ohta, Shigeyuki Kitamura　.
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 41 Issue: 4 Pages: 551-560
- DOI
  10.2131/jts.41.551
- NAID
  130005165024
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K00559
[Journal Article] Estimation of occupational exposure to drugs during tablet crushing2016
- Author(s)
  Shizuko Maeda , Eiko Takahashi , Yoshitaka Tayama , Shigeyuki Kitamura , Toyohisa Tsukamoto , Katsushi Miyake , Kazumi Sugihara
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 3 Issue: 4 Pages: 177-183
- DOI
  10.2131/fts.3.177
- NAID
  130005158221
- ISSN
  2189-115X
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460247, KAKENHI-PROJECT-16K08428
[Journal Article] Estimation of occupational exposure to drugs during tablet crushing.2016
- Author(s)
  Shizuko Maeda, Eiko Takahashi, Yoshitaka Tayama, Shigeyuki Kitamura, Toyohisa Tsukamoto, Katsushi Miyake, Kazumi Sugihara.
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 3 Pages: 177-183
- NAID
  130005158221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00559
[Journal Article] Variability of Zalepron 5-oxidase activity in mice and humans, and inhibition by raloxifene.2016
- Author(s)
  Tanoue C., Sugihara K., Tayama Y., Uramaru N., Watanabe Y., Ohta S., Kitamura S.
- Journal Title
  
  Drug Metabolism Letters
  
  Volume: 10 Issue: 4 Pages: 278-285
- DOI
  10.2174/1872312810666161227145358
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K00559, KAKENHI-PROJECT-17K08401
[Journal Article] Predictability of plasma concentration-time curves in humans using single-species allometric scaling of chimeric mice with humanized liver.2015
- Author(s)
  Sanoh, S., Naritomi Y., Fujimoto M., Sato K., Kawamura A., Horiguchi A., Sugihara K., Kotake Y., Ohshita H., Tateno C., Horie T., Kitamura S., Ohta S.
- Journal Title
  
  Xenobiotica
  
  Volume: 45 Issue: 7 Pages: 605-614
- DOI
  10.3109/00498254.2015.1007112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25340049
[Journal Article] Hydrolytic metabolism of phenyl and benzyl salicylates, fragrances and flavoring agents in foods, by microsomes of rat and human tissues2015
- Author(s)
  Ozaki H., Sugihara K., Tamura Y., Fujino C., Watanabe Y., Uramaru N., Sone T., Ohta S., Kitamura S.
- Journal Title
  
  Food Chem Toxicol
  
  Volume: 86. Pages: 116-123
- DOI
  10.1016/j.fct.2015.08.024
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25340049
[Journal Article] Metabolism of UV-filter benzophenone-3 by rat and human liver microsomes and its effect on endocrine-disrupting activity.2015
- Author(s)
  Yoko Watanabe, Hiroyuki Kojima, Shinji Takeuchi, Naoto Uramaru, Seigo Sanoh, Kazumi Sugihara, Shigeyuki Kitamura, and Shigeru Ohta
- Journal Title
  
  Toxicology and Applied Pharmacology
  
  Volume: 282 Issue: 2 Pages: 119-128
- DOI
  10.1016/j.taap.2014.12.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590773, KAKENHI-PROJECT-25340049, KAKENHI-PROJECT-24390172
[Journal Article] Aryl Hydrocarbon Receptor Ligand Activity of Extracts from 62 Herbal Medicines and Effect on Cytochrome P450 Activity2015
- Author(s)
  Harada A., Sugihara K., Watanabe Y., Yamaji S., Kitamura S., Ohta S.
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 135 Issue: 10 Pages: 1185-1196
- DOI
  10.1248/yakushi.15-00153
- NAID
  130005100636
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2015-10-01
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25340049
[Journal Article] Significance of aldehyde oxidase during drug development: Effects on drug metabolism, pharmacokinetics, toxicity, and efficacy2015
- Author(s)
  Sanoh, S., Tayama Y., Sugihara K., Kitamura S., Ohta S.
- Journal Title
  
  .Drug Metab. Pharmacokinet.
  
  Volume: 30 Issue: 1 Pages: 52-63
- DOI
  10.1016/j.dmpk.2014.10.009
- NAID
  50014415980
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25340049
[Journal Article] Current stutus of prediction of drug disposition and toxicity in humans using chimeric mice with humanized liver2014
- Author(s)
  Kitamura S. and Sugihara K.
- Journal Title
  
  Xenobiotica
  
  Volume: 44 Issue: 2 Pages: 123-134
- DOI
  10.3109/00498254.2013.868062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25340049
[Journal Article] In vitro metabolism of cis-and trans-permethrin by rat liver microsomes, and its effect on estrogenic and anti-androgenic activities2014
- Author(s)
  Tange, S., Fujimoto, N., Uramaru, N., Sugihara, K., Ohta, S., Kitamura, S
- Journal Title
  
  Environ. Toxicol. Pharmacol
  
  Volume: 37 Issue: 3 Pages: 996-1005
- DOI
  10.1016/j.etap.2014.03.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23510076, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
[Journal Article] Fluorometric assessment of acetaminophen-induced toxicity in rat hepatocyte spheroids seeded on micro-space cell culture plates2014
- Author(s)
  Sanoh S, Santoh M, Takagi M, Kanayama T, Sugihara K, Kotake Y, Ejiri Y, Horie T, Kitamura S, Ohta S
- Journal Title
  
  Toxicol In vitro
  
  Volume: (in press) Issue: 6 Pages: 192-197
- DOI
  10.1016/j.tiv.2014.05.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24790111, KAKENHI-PROJECT-25340049
[Journal Article] Strain Difference of Oxidative Metabolism of the Sedative-Hypnotic Zaleplon byAldehyde Oxidase and Cytochrome P450 in Vivo and in Vitro in Rats.2013
- Author(s)
  Tanoue C, Sugihara K, Uramaru N, Watanabe Y, Tayama Y, Ohta S, Kitamura S.
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: In Press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390030
[Journal Article] Comparative study of the hydrolytic metabolism of methyl-, ethyl-, propyl-, butyl-, heptyl- and dodecylparaben by microsomes of various rat and human tissues2013
- Author(s)
  Ozaki H., Sugihara K., WatanabeY., Fujino C., Uramaru N., Sone T., Ohta S., Kitamura S
- Journal Title
  
  Xenobiotica
  
  Volume: (in press) Issue: 12 Pages: 1064-1072
- DOI
  10.3109/00498254.2013.802059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
[Journal Article] Strain Difference of Oxidative Metabolism of the Sedative-hypnotic Zaleplon by Aldehyde Oxidase and Cytochrome P450 In Vivo and In Vitro in Rats2013
- Author(s)
 Tanoue C., Sugihara K., Uramaru N., Watanabe Y., Tayama Y., Ohta S., Kitamura S
- Journal Title
 
 Drug Metabolism and Pharmacokinetics
 
 Volume: 28 Issue: 3 Pages: 269-273
- DOI
 10.2133/dmpk.DMPK-12-NT-103
- NAID
 130004463299
- ISSN
 1347-4367, 1880-0920
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-22510071
[Journal Article] 2,5-Dihydroxy-4-methoxybenzophenone: a novel major in vitro metabolite of benzophenone-3 formed by rat and human liver microsomes2013
- Author(s)
  Kamikyouden N., Sugihara K., Watanabe Y., Uramaru N., Murahashi T., Kuroyanagi M., Sanoh S., Ohta S., Kitamura S
- Journal Title
  
  Xenobiotica
  
  Volume: 43(6) Issue: 6 Pages: 514-519
- DOI
  10.3109/00498254.2012.742217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-23390030, KAKENHI-PROJECT-23659053, KAKENHI-PROJECT-24790111, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
[Journal Article] Strain difference of oxidative metabolism of the sedative-hypnotic zaleplon by aldehyde oxidase and cytochrome P450 in vivo and in vitro in rats2013
- Author(s)
  Tanoue C, Sugihara K, Uramaru N, Watanabe Y, Tayama Y, Ohta S, Kitamura S
- Journal Title
  
  Drug Metab Pharmacokinet
  
  Volume: 28(3) Pages: 269-73
- NAID
  130004463299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390030
[Journal Article] Cell type-dependent agonist/antagonist activities of polybrominated diphenyl ethers2013
- Author(s)
  Nakamura N, Matsubara K, Sanoh S, Ohta S, Uramaru N, Kitamura S, Yamaguchi M, Sugihara K, Fujimoto N
- Journal Title
  
  Toxicol Lett
  
  Volume: 223(2) Issue: 2 Pages: 192-7
- DOI
  10.1016/j.toxlet.2013.09.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390030, KAKENHI-PROJECT-23510076, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
[Journal Article] Photodegradation of pharmaceuticals in the aquatic environment by sunlight and UV-A, -B and -C irradiation2013
- Author(s)
  Kawabata K., Sugihara K., Sanoh S., Kitamura S., Ohta S
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 38 Issue: 2 Pages: 215-223
- DOI
  10.2131/jts.38.215
- NAID
  10031151425
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-24790126
[Journal Article] Prediction of Human Metabolism of the Sedative-Hypnotic Zaleplon Using Chimeric Mice Transplanted with Human Hepatocytes2013
- Author(s)
  Tanoue C., Sugihara K., Uramaru N., Tayama Y., Watanabe Y., Horie T., Ohta S., Kitamura S
- Journal Title
  
  Xenobiotica
  
  Volume: (in press) Issue: 11 Pages: 956-962
- DOI
  10.3109/00498254.2013.788232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
[Journal Article] Developmental Changes of Aldehyde Oxidase Activity and Protein Expression in Human Liver Cytosol2012
- Author(s)
  Tayama Y., Sugihara K., Sanoh S., Miyake K., Kitamura S., Ohta S.
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 27 Issue: 5 Pages: 543-547
- DOI
  10.2133/dmpk.DMPK-11-NT-124
- NAID
  130004463273
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-23790212
[Journal Article] Effects of polybrominated diphenyl ethers (PBDEs) and their derivatives on protein disulfide isomerase activity and growth hormone release of GH3 cells.2012
- Author(s)
  Hashimoto S, Yoshimura H, Okada K, Uramaru N, Sugihara K, Kitamura S, and Imaoka S.
- Journal Title
  
  Chem. Res. Toxicol.
  
  Volume: 25(3) Issue: 3 Pages: 656-63
- DOI
  10.1021/tx200374s
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310045, KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-23655162
[Journal Article] Prediction of in vive hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver2012
- Author(s)
  Sanoh, Seigo ; Horiguchi, Aya ; Sugihara, Kazumi ; Kotake, Yaichiro ; Tayama, Yoshitaka ; Ohshita, Hiroki ; Tate noo, Chise ; Horie, Toni ; Kitamura, Shigeyuki ; Ohta, Shigeru
- Journal Title
  
  Drug Metabolism & Disposition
  
  Volume: 40(2) Pages: 322-328
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Effects of Polybrominated Diphenyl Ethers(PBDEs) and Their Derivatives on Protein Disulfide Isomerase Activity and Growth Hormone Release of GH3 Cells2012
- Author(s)
  Hashimoto, Shako ; Yoshimura, Hiromi ; Okada, Kazushi ; Uramaru, Naoto ; Sugihara, Kazumi ; Kitamura, Shigeyuki ; Imaoka, Susumu
- Journal Title
  
  Chemical Research in Toxicology
  
  Volume: 25(3) Pages: 656-663
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide.2012
- Author(s)
  Matsubara K., Sanoh S., Ohta S., Kitamura S., Fujimoto N
- Journal Title
  
  Toxicol Lett
  
  Volume: 208 Issue: 1 Pages: 30-35
- DOI
  10.1016/j.toxlet.2011.10.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-23390030, KAKENHI-PROJECT-23510076
[Journal Article] Animproved thyroid hormone reporter assay to determine the thyroid hormone-likeactivity of amiodaronebithionol, closantel and rafoxanide2012
- Author(s)
  Matsubara K., Sanoh S., Ohta S., Kitamura S., Sugihara K., Fujimoto N.
- Journal Title
  
  Toxicol. Lett
  
  Volume: 208 Pages: 30-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510065
[Journal Article] Predictability of Metabolism of Ibuprofen and Naproxen Using Chimeric Mice with Human Hepatocytes2012
- Author(s)
  Sanoh S., Horiguchi A., Sugihara K., Kotake Y., Tayama Y., Uramaru N., Ohshita H., Tateno C., Horie T., Kitamura S., Ohta S
- Journal Title
  
  Drug Metab Dispos
  
  Volume: 40(2) Issue: 2 Pages: 2267-2272
- DOI
  10.1124/dmd.111.040923
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-22790109, KAKENHI-PROJECT-23310047, KAKENHI-PROJECT-23390030, KAKENHI-PROJECT-23659053
[Journal Article] An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide2012
- Author(s)
  Matsubara, Kana ; Sanoh, Seigo ; Ohta, Shigeru ; Kitamura, Shigeyuki ; Sugihara, Kazumi ; Fujimoto, Nariaki
- Journal Title
  
  Toxicology Letters
  
  Volume: 208(1) Pages: 30-35
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Predictability of metabolism of ibuprofen and naproxen using chimeric mice with human hepatocytes2012
- Author(s)
  Sanoh S, Horiguchi A, Sugihara K, Kotake Y, Tayama Y, Uramaru N, Ohshita H, Tateno C, Horie T, Kitamura S, Ohta S
- Journal Title
  
  Drug Metab Dispos
  
  Volume: 40(12) Issue: 12 Pages: 2267-72
- DOI
  10.1124/dmd.112.047555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310047, KAKENHI-PROJECT-23390030, KAKENHI-PROJECT-23659053, KAKENHI-PROJECT-24651061, KAKENHI-PROJECT-24790111, KAKENHI-PROJECT-24790126
[Journal Article] An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide2012
- Author(s)
  Matsubara K, Sanoh S, Ohta S, Kitamura S, Sugihara K, Fujimoto N
- Journal Title
  
  Toxicol Lett
  
  Volume: 208 Pages: 30-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Effects of Polybrominated Diphenyl Ethers (PBDEs) and Their Derivatives on Protein Disulfide Isomerase Activity and Growth Hormone Release of GH3 Cells2012
- Author(s)
  Hashimoto S, Yoshimura H, Okada K, Uramaru N, Sugihara K, Kitamura S
- Journal Title
  
  Chem Res Toxicol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver2012
- Author(s)
  Sanoh S, Horiguchi A, Sugihara K, Kotake Y, Tayama Y, Ohshita H
- Journal Title
  
  Drug Metab Dispos
  
  Volume: 40 Pages: 322-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Ultraviolet-photoproduct of acetaminophen: Structure determination and evaluation of ecotoxicological effect.2012
- Author(s)
  Kawabata K., Sugihara K., Sanoh S., Kitamura S.,Ohta S
- Journal Title
  
  J Photochem Photobiol A Chem
  
  Volume: 249 Pages: 29-35
- DOI
  10.1016/j.jphotochem.2012.07.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071
[Journal Article] Effect oftea beverages on aldehyde oxidase activity2011
- Author(s)
  Tayama Y, Sugihara K, Sanoh S, MiyakeK, Morita S, Kitamura S, Ohta S.
- Journal Title
  
  Drug Metab Pharmacokinet
  
  Volume: 26 Pages: 94-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20406005
[Journal Article] Effect of tea beverages on aldehyde oxidase activity2011
- Author(s)
  Tayama Y, Sugihara K, Sanoh S, Miyake K, Morita S, Kitamura S, Ohta
- Journal Title
  
  Drug Metab Pharmacokinet
  
  Volume: 26 Pages: 94-101
- NAID
  130004463166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Effect of tea beverages on aldehyde oxidase activity2011
- Author(s)
  Tayama Yoshitaka ; Sugihara Kazumi ; Sanoh Seigo ; Miyake Katsushi ; Morita Shushi ; Kitamura Shigeyuki ; Ohta Shy
- Journal Title
  
  Drug Metabolism and Pharmacokinetics 26(1)
  
  Pages: 94-101
- NAID
  130004463166
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Effect of tea beverages on aldehyde oxidase activity2011
- Author(s)
  Tayama, Yoshitaka ; Sugihara, Kazumi ; Sanoh, Seigo ; Miyake, Katsushi ; Marita, Shushi ; Kitamura, Shigeyuki ; Ohta, Shigeru
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 26(1) Pages: 94-101
- NAID
  130004463166
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Effect of Tea Beverages on Aldehyde Oxidase Activity2011
- Author(s)
  Tayama Y., Sugihara K., Sanoh S., Miyake K., Morita S., Kitamura S., Ohta S
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 26 Issue: 1 Pages: 94-101
- DOI
  10.2133/dmpk.DMPK-10-NT-078
- NAID
  130004463166
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Data Source
  KAKENHI-PROJECT-22510071
[Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver.2010
- Author(s)
  Nurrochmad A, Ishii Y, Nakanoh H, Inoue T, Horie T, Sugihara K, Ohta S, Taketomi A, Maehara Y, Yamada H.
- Journal Title
  
  Drug Metab.Pharmacokinet. 25
  
  Pages: 262-273
- NAID
  10027582853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390040
[Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver.2010
- Author(s)
  Nurrochmad A, Ishii Y, Nakanoh H, Inoue T, Horie T, Sugihara K, Ohta S, Taketomi A, Maehara Y, Yamada H
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: 25(3) Pages: 262-273
- NAID
  10027582853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] 在宅で発生する向精神薬等取扱注意医薬品の残薬処理の実態調査2010
- Author(s)
  杉原数美
- Journal Title
  
  有害・医療廃棄物研究
  
  Volume: 22(2) Pages: 82-85
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver2010
- Author(s)
  Nurrochmad, Ariel ; Ishii, Yuji ; Nakanoh, Hitomi ; Inoue, Tae ; Horie, Torn ; Sugihara, Kazumi ; Ohta, Shigeru ; Taketomi, Akinobu ; Maehara, Yoshihiko ; Yamada, Hideyuki
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 25(3) Pages: 262-373
- NAID
  10027582853
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Effect of tea beverages on aldehyde oxidase activity.2010
- Author(s)
  Tayama Y, Sugihara K, Sanoh S, Miyake K, Morita S, Kitamura S, Ohta S.
- Journal Title
  
  Drug Metab.Pharmacokinet. 26
  
  Pages: 94-101
- NAID
  130004463166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390040
[Journal Article] 在宅で発生する向精神薬等取扱注意医薬品の残薬処理の実態調査2010
- Author(s)
  杉原数美
- Journal Title
  
  有害・医療廃棄物研究
  
  Volume: 22(2) Pages: 82-85
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver.2010
- Author(s)
  Nurrochmad A, Ishii Y, Nakanoh H, Inoue T, Horie T, Sugihara K, Ohta S, Taketomi A, Maehara Y, Yamada H
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: 25(3) Pages: 262-273
- NAID
  10027582853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver2010
- Author(s)
  Nurrochmad A, Ishii Y, Nakanoh H, InoueT, Horie T, Sugihara K, Ohta S, Taketomi A, Maehara Y, Yamada H.
- Journal Title
  
  Drug MetabPharmacokinet
  
  Volume: 25 Pages: 262-273
- NAID
  10027582853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20406005
[Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver2010
- Author(s)
  Nurrochmad Arief ; Ishii Yuji ; Nakanoh Hitomi ; Inoue Tae ; Horie Toru ; Sugihara Kazumi ; Ohta Shigeru ; Taketomi Akinobu ; Maehara Yoshihiko ; Yamada Hideyuki
- Journal Title
  
  Drug Metabolism and Pharmacokinetics 25(3)
  
  Pages: 262-273
- NAID
  10027582853
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Effect of tea beverages on aldehyde oxidase activity.2010
- Author(s)
  Tayama Y, Sugihara K, Sanoh S, Miyake K, Morita S, Kitamura S, Ohta S
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: 26(1) Pages: 94-101
- NAID
  130004463166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Effect of tea beverages on aldehyde oxidase activity.2010
- Author(s)
  Tayama Y, Sugihara K, Sanoh S, Miyake K, Morita S, Kitamura S, Ohta S
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: 26(1) Pages: 94-101
- NAID
  130004463166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] 広島県内における在宅医療廃棄物の発生・回収・廃棄に関する調査2009
- Author(s)
  杉原数美, 等
- Journal Title
  
  有害・医療廃棄物研究 21
  
  Pages: 23-23
- NAID
  40017216811
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Prediction of human disposition toward S-3H-warfarin using chimeric mice with humanized liver.2009
- Author(s)
  Inoue T, Sugihara K, Ohshita H, Horie T, Kitamura S, Ohta S.
- Journal Title
  
  Drug Metab.Pharmacokinet. 24
  
  Pages: 153-160
- NAID
  10025723190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390040
[Journal Article] Current situation of drug in for mation in the kindergarten andnursery teacher : a pilot study2009
- Author(s)
  Tayama Y, Miyake K, Kanazawa E, KanekoT, Sugihara K, Toyomi A, Morita S, Kobayashi M, Ohta S.
- Journal Title
  
  YakugakuZasshi
  
  Volume: 129 Pages: 617-622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20406005
[Journal Article] Prediction of human disposition toward S3Hwarfarin using chimeric mice with humanized liver2009
- Author(s)
  Inoue, Tae ; Sugihara, Kazumi ; Ohshita, Hiroki ; Horie, Torn ; Kitamura, Shigeyuki ; Ohta, Shigeru
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 24(2) Pages: 153-160
- NAID
  10025723190
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Prediction of humandisposition toward S-3H-warfarin usingchimeric mice with humanized liver2009
- Author(s)
  Inoue T, Sugihara K, Ohshita H, HorieT, Kitamura S, Ohta S.
- Journal Title
  
  DrugMetab Pharmacokinet
  
  Volume: 24 Pages: 153-160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20406005
[Journal Article] Current situation of drug information in the kindergarten and nursery teacher : a pilot study2009
- Author(s)
  Tayama, Yoshitaka ; Miyake, Katsushi ; Kanazawa, Erl ; Kaneko, Tetuo ; Sugihara, Kazumi ; Toyomi, Atsushi ; Marita, Shushi ; Kobayashi, Masao ; Ohta, Shigeru
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 129(5) Pages: 617-622
- NAID
  130000136166
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Disruption of thyroid hormone function by environmental Pollutants2009
- Author(s)
  Kashiwagi, Keiko, Furuno, Nobuaki, Kitamura, Shigeyuki, Ohta, Shigeru, Sugihara, Kazumi, Utsumi, Kozo, Hanada, Hideki, Taniguchi Kikuyo, Suzuki, Ken-ichi, Kashiwagi, Akihiko
- Journal Title
  
  Journal of Health Science 55(2)
  
  Pages: 147-160
- NAID
  110007161008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009
- Author(s)
  Kojima, Hiroyuki, Takeuchi, Shinji, Uramaru, Naoto, Sugihara, Kazumi, Yoshida, Takahiko, Kitamura, Shigeyuki
- Journal Title
  
  Environmental Health Perspectives 17(8)
  
  Pages: 1210-1218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009
- Author(s)
  Kojima Hiroyuki ; Takeuchi Shinji ; Uramaru Naoto ; Sugihara Kazumi ; Yoshida Takahiko ; Kitamura Shigeyuki
- Journal Title
  
  Environmental Health Perspectives 117(8)
  
  Pages: 1210-1218
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Modulation of connexin 43 in rotenone-induced model of Parkinson's disease2009
- Author(s)
  Kawasaki A.; Hayashi T.; Nakachi K.; Trosko J. E.; Sugihara K.; Kotake Y.; Ohta S.
- Journal Title
  
  Neuroscience 160(1)
  
  Pages: 61-68
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Disruption of thyroid hormone function by environmental pollutants2009
- Author(s)
  Kashiwagi, Keiko, Furuno, Nobuaki, Kitamura, Shigeyuki, Ohta, Shigeru, Sugihara, Kazumi, Utsumi, Kozo, Hanada, Hideki, Taniguchi Kikuyo, Suzuki, Ken-ichi, Kashiwagi, Akihiko
- Journal Title
  
  Journal of Health Science 55(2)
  
  Pages: 147-160
- NAID
  110007161008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] 広島県内における在宅医療廃棄物の発生・回収・廃棄に関する調査2009
- Author(s)
  杉原数美, 等
- Journal Title
  
  有害・医療廃棄物研究 21
  
  Pages: 23-23
- NAID
  40017216811
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] 広島県内における在宅医療廃棄物の発生・回収・廃棄に関する調査2009
- Author(s)
  杉原数美等
- Journal Title
  
  有害・医療廃棄物研究 21(in press)
- NAID
  40017216811
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Disruption of thyroid hormone function by environmental pollutants2009
- Author(s)
  Kashiwagi, Keiko ; Furuno, Nobuaki ; Kitamura, Shigeyuki ; Ohta, Shigeru ; Sugihara, Kazumi ; Utsumi, Kozo ; Hanada, Hideki ; Taniguchi, Kikuyo ; Suzuki, Ken-ichi ; Kashiwagi, Akihiko
- Journal Title
  
  Journal of Health Science
  
  Volume: 55(2) Pages: 147-160
- NAID
  110007161008
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Modulation of connexin 43 in rotenoneinduced model of Parkinson's disease2009
- Author(s)
  Kawasaki, A.; Hayashi, T.; Nakachi, K.; Trosko, J. E.; Sugihara, K.; Kotake, Y.; Ohta, S
- Journal Title
  
  Neuroscience
  
  Volume: 160(1) Pages: 61-68
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Modulation of connexin 43 in rotenone-induced model of Parkinson's disease.2009
- Author(s)
  Kawasaki A, Hayashi T, Nakachi K, Trosko JE, Sugihara K, Kotake Y, Ohta S.
- Journal Title
  
  Neuroscience 160
  
  Pages: 61-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390040
[Journal Article] Current situation of drug information in the kindergarten and nursery teacher : a pilot study2009
- Author(s)
  Tayama Yoshitaka ; Miyake Katsushi ; Kanazawa Eri ; Kaneko Tetuo ; Sugihara Kazumi ; Toyomi Atsushi ; Morita Shushi ; Kobayashi Masao ; Ohta Shigeru
- Journal Title
  
  Yakugaku Zasshi 129(5)
  
  Pages: 617-622
- NAID
  130000136166
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009
- Author(s)
  Kojima, Hiroyuki ; Takeuchi, Shinji ; Uramaru, Naoto ; Sugihara, Kazumi ; Yoshida, Takahiko ; Kitamura, Shigeyuki
- Journal Title
  
  Environmental Health Perspectives
  
  Volume: 117(8) Pages: 1210-1218
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009
- Author(s)
  Kojima, Hiroyuki, Takeuchi, Shinji, Uramaru, Naoto, Sugihara, Kazumi, Yoshida, Takahiko, Kitamura, Shigeyuki
- Journal Title
  
  Environmental Health Perspectives 17(8)
  
  Pages: 1210-1218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Disruption of thyroid hormone function by environmental pollutants2009
- Author(s)
  Kashiwagi Keiko ; Furuno Nobuaki ; Kitamura Shigeyuki ; Ohta Shigeru ; Sugihara Kazumi ; Utsumi Kozo ; Hanada Hideki ; Taniguchi Kikuyo ; Suzuki Ken-ichi ; Kashiwagi Akihiko
- Journal Title
  
  Journal of Health Science 55(2)
  
  Pages: 147-160
- NAID
  110007161008
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Current situation of drug information in the kindergarten and nursery teacher : a pilot study.2009
- Author(s)
  Tayama Y, Miyake K, Kanazawa E, Kaneko T, Sugihara K, Toyomi A, Morita S, Kobayashi M, Ohta S.
- Journal Title
  
  Yakugaku Zasshi. 129
  
  Pages: 617-622
- NAID
  130000136166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390040
[Journal Article] Prediction of human disposition toward S-3H-warfarin using chimeric mice with humanized liver2009
- Author(s)
  Inoue Tae ; Sugihara Kazumi ; Ohshita Hiroki ; Horie Toru ; Kitamura Shigeyuki ; Ohta Shigeru
- Journal Title
  
  Drug Metabolism and Pharmacokinetics 24(2)
  
  Pages: 153-160
- NAID
  10025723190
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] CYP2C9-catalyzed metabolism of S-warfarin to 7-hydroxywarfarin in vivo and in vitro in chimeric mice with humanized liver2008
- Author(s)
  Inoue Tae ; Nitta Kayoko ; Sugihara Kazumi ; Horie Toru ; Kitamura Shigeyuki ; Ohta Shigeru
- Journal Title
  
  Drug Metabolism and Disposition 36(12)
  
  Pages: 2429-2433
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Metabolic activation of proestrogens in the environment by cytochrome P450 system2008
- Author(s)
  Kitamura, S., Sugihara K., Sanoh, S., Fujimoto, N., Ohta, S.
- Journal Title
  
  J. Health Sci. 54
  
  Pages: 343-355
- NAID
  110006835680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510065
[Journal Article] Metabolic activation of proestrogens in the environment by cytochrome P450 system2008
- Author(s)
  Kitamura Shigeyuki ; Sugihara Kazumi ; Sanoh Seigo ; Fujimoto Nariaki ; Ohta Shigeru
- Journal Title
  
  Journal of Health Science 54(4)
  
  Pages: 343-355
- NAID
  110006835680
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo2008
- Author(s)
  Sugihara Kazumi ; Okayama Takashige ; Kitamura Shigeyuki ; Yamashita Keisuke ; Yasuda Mineo ; Miyairi Shinichi ; Minobe Yasushi ; Ohta Shigeru
- Journal Title
  
  Archives of Toxicology 82(1)
  
  Pages: 5-11
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo.2008
- Author(s)
  Sugihara K, Okayama T, Kitamura S, Yamashita K, Yasuda M, Miyairi S, Minobe Y, Ohta S.
- Journal Title
  
  Arch.Toxicol. 82
  
  Pages: 5-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390040
[Journal Article] Study on the pharmaceuticals in hospital sewage and their toxicities in the aquatic environment2008
- Author(s)
  Sugihara Kazumi
- Journal Title
  
  Yakugaku Kenkyu no Shinpo, (2009) 25
  
  Pages: 99-105
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Aldehyde oxidase-catalyzed metabolism of N1-methylnicotinamide in vivo and in vitro in chimeric mice with humanized liver2008
- Author(s)
  Kitamura Shigeyuki ; Nitta Kayoko ; Tayama Yoshitaka ; Tanoue Chiaki ; Sugihara Kazumi ; Inoue Tae ; Horie Toru ; Ohta Shigeru
- Journal Title
  
  Drug Metabolism and Disposition 36(7)
  
  Pages: 1202-1205
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] CYP2C9-catalyzed metabolism of S-warfarin to 7-hydroxywarfarin in vivo and in vitro in chimeric mice with humanized liver.2008
- Author(s)
  Inoue T, Nitta K, Sugihara K, Horie T, Kitamura S, Ohta S.
- Journal Title
  
  Drug Metab.Dispos. 36
  
  Pages: 2429-2433
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390040
[Journal Article] Aldehyde oxidase-catalyzed metabolism ofN1-methylnicotinamide in vivo and in vitroin chimeric mice with humanized liver2008
- Author(s)
  Kitamura S, Nitta K, Tayama Y, TanoueC, Sugihara K, Inoue T, Horie T, Ohta S.
- Journal Title
  
  Drug Metab Dispos
  
  Volume: 36 Pages: 1202-1205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20406005
[Journal Article] Affinity for Thyroid Hormone and Estrogen Receptors of Hydroxylated Polybrominated Diphenyl Ethers2008
- Author(s)
  Kitamura, S., Shinohara, S., Iwase, S., Sugihara, K., Uramaru, N., Shigematsu, N., Fujimoto, N., Ohta, S.
- Journal Title
  
  J. Health Sci. 54
  
  Pages: 607-614
- NAID
  110006935591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510065
[Journal Article] Aldehyde oxidase-catalyzed metabolism of N1-methylnicotinamide in vivo and in vitro in chimeric mice with humanized liver.2008
- Author(s)
  Kitamura S, Nitta K, Tayama Y, Tanoue C, Sugihara K, Inoue T, Horie T, Ohta S.
- Journal Title
  
  Drug.Metab.Dispos. 36
  
  Pages: 1202-1205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390040
[Journal Article] Affinity for thyroid hormone and estrogen receptors of hydroxylated polybrominated diphenyl ethers2008
- Author(s)
  Kitamura Shigeyuki ; Shinohara Seiji ; Iwase Eri ; Sugihara Kazumi ; Uramaru Naoto ; Shigematsu Hidenari ; Fujimoto Nariaki ; Ohta Shigeru
- Journal Title
  
  Journal of Health Science 54(5)
  
  Pages: 607-614
- NAID
  110006935591
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Metabolicactivation of proestrogens in theenvironment by cytochrome P450 system2008
- Author(s)
  Kitamura, S., Sugihara K., Sanoh, S., Fujimoto, N., Ohta, S.
- Journal Title
  
  J. Health Science
  
  Volume: 54 Pages: 343-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510065
[Journal Article] Study on the pharmaceuticals in hospital sewage and their toxicities in the aquatic environment2008
- Author(s)
  Sugihara, Kazumi
- Journal Title
  
  Yakugaku Kenkyu no Shinpo
  
  Volume: 25 Pages: 99-105
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Effects of endocrine disrupting chemicals on amphibian metamorphosis and mitochondrial membrane permeability transition2008
- Author(s)
  Kashiwagi Akihiko ; Utsumi Kozo ; Kashiwagi Keiko ; Ohta Shigeru ; Sugihara Kazumi ; Hanada Hideki ; Kitamura Shigeyuki
- Journal Title
  
  Journal of Health Science 54(3)
  
  Pages: 273-280
- NAID
  110006684374
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] CYP2C9-catalyzedmetabolism of S-warfarin to 7-hydroxywarfarinin vivo and in vitro in chimericmice with humanized liver2008
- Author(s)
  Inoue T, Nitta K, Sugihara K, Horie T, Kitamura S, Ohta S.
- Journal Title
  
  Drug MetabDispos
  
  Volume: 36 Pages: 2429-2433
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20406005
[Journal Article] Affinity for ThyroidHormone and Estrogen Receptors of Hydroxylated Polybrominated Diphenyl Ethers.2008
- Author(s)
  Kitamura, S., Shinohara, S., Iwase, S., Sugihara, K., Uramaru, N., Shigematsu, N., Fujimoto, N., Ohta, S.
- Journal Title
  
  J. Health Science
  
  Volume: 54 Pages: 607-614
- NAID
  110006935591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510065
[Journal Article] Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo2007
- Author(s)
  Sugihara et al.
- Journal Title
  
  archives of Toxicology (In press)
- Data Source
  KAKENHI-PROJECT-18590118
[Journal Article] Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo2007
- Author(s)
  Sugihara, et. al.
- Journal Title
  
  Archives of Toxicology 82
  
  Pages: 5-11
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590118
[Journal Article] The in vitro metabolism of a pyrethroid insecticide, permethrin, and its hydrolyzed oroducts in rats2007
- Author(s)
  Y., Nakamura, K., Sugihara, T., Sone, M., Isobe, S., Ohta, S., Kitamura
- Journal Title
  
  Toxicology 235
  
  Pages: 176-184
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Journal Article] Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo2007
- Author(s)
  K., Sugihara, T., Okayama, S., Kitamura, K., Yamashita, M., Yasuda, S., Miyairi, Y., Minobe, S., Ohta
- Journal Title
  
  Archives of Toxicology 82
  
  Pages: 5-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Journal Article] Effects of stilbene and related compounds on reproductive organs in B6C3F1/Crj mouse H. Fujita, Y. Okimura, T. Utsumi, S. Kitamura, H. Kuroki, T. Otsuki, J. Sasaki, A. Kashiwag2006
- Author(s)
  S., Sanoh, S., Kitamura, R., Kohta, K., Sugihara, S., Ohta, H., Watanabe
- Journal Title
  
  Journal of Health Sciences 52(5)
  
  Pages: 613-622
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Journal Article] Estimation of aldehyde oxidase activity in vivo from conversion ratio of Nl-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats.2006
- Author(s)
  Sugihara, Kazumi,. et al.
- Journal Title
  
  Drug Metabolism and Disposition 34(2)
  
  Pages: 208-212
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590102
[Journal Article] Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats.2006
- Author(s)
  Sugihara, Kazumi, etal.
- Journal Title
  
  Drug Metabolism and Disposition 34(2)
  
  Pages: 208-212
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590102
[Journal Article] Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats.2006
- Author(s)
  Sugihara, Kazumi, et al.
- Journal Title
  
  Drug Metabolism and Disposition 34(2),
  
  Pages: 208-212
- Data Source
  KAKENHI-PROJECT-17590102
[Journal Article] Comparative study of the endocrine-disrupting activity of bisphenol A and 19 related compounds2005
- Author(s)
  S.Kitamura, T.Suzuki, S.Sanoh, R.Kohta, N.Jinno, K.Sugiharaら
- Journal Title
  
  Toxicological Sciences 84
  
  Pages: 249-259
- Data Source
  KAKENHI-PROJECT-16590092
[Journal Article] Estrogenic and antiandrogenic activities of 17 benzophenone derivatives used as UV stabilizers and sunscreen2005
- Author(s)
  T.Suzuki, S.Kitamura, R.Khota, K.Sugihara, N.Fujimoto, S.Ohta
- Journal Title
  
  Toxicology and Applied Pharmacology 203
  
  Pages: 9-17
- Data Source
  KAKENHI-PROJECT-16590092
[Journal Article] Thyroid hormone-like and estrogenic activity of hydroxylated PCBs in cell culture2005
- Author(s)
  S.Kitamura, N.Jinno, T.Suzuki, K.Sugihara, S.Ohtaら
- Journal Title
  
  Toxicology 208
  
  Pages: 377-387
- Data Source
  KAKENHI-PROJECT-16590092
[Journal Article] Aryl hydrocarbon receptor-mediated induction of microsomal drug-metabolizing enzyme activity by indirubin and indigo2004
- Author(s)
  K.Sugihara, S.Kitamura, T.Yamada, T.Okayama, S.Ohta
- Journal Title
  
  Biochemical and Biophysical Research Communication 318
  
  Pages: 571-578
- Data Source
  KAKENHI-PROJECT-16590092
[Presentation] 環境中医薬品類の植物発芽成長および植物細胞への影響調査2024
- Author(s)
  杉原数美, 井村太郎, 定松礼士, 氏原稜, 清水良, 古武弥一郎
- Organizer
  日本薬学会144年会
- Data Source
  KAKENHI-PROJECT-23K11442
[Presentation] 植物種子発芽成長への環境中医薬品類の影響2023
- Author(s)
  井村太郎, 定松礼士, 氏原稜, 宮野侑輝，樽本良介, 清水良, 杉原数美
- Organizer
  第62回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-23K11442
[Presentation] 植物種子発芽成長への環境中医薬品類の影響2023
- Author(s)
  氏原　稜, 定松礼士, 井村太郎, 宮野侑輝，樽本良介, 清水良, 杉原数美
- Organizer
  フォーラム2023：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-23K11442
[Presentation] ラットにおける肝臓および血漿中xanthine oxidoreductaseの活性とタンパク発現に及ぼす概日リズムの影響2022
- Author(s)
  田山剛崇、前田志津子、田邉建志、岡村友理香、杉原数美、三宅勝志
- Organizer
  日本薬学会　第142年会
- Data Source
  KAKENHI-PROJECT-19K07182
[Presentation] Xanthine oxidoreductase(XOR)活性とSirtuin-1の活性変動に関する検討2022
- Author(s)
  森脇智也、田山剛崇、前田志津子、岡村友理香、杉原数美、三宅勝志
- Organizer
  第３２回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-19K07182
[Presentation] 血漿中xanthine oxidoreductaseタンパク発現における概日変動の検討2021
- Author(s)
  田邉建志, 田山剛崇, 前田志津子, 西村さとみ, 喜多智生, 岡村友理香, 杉原数美, 三宅勝志
- Organizer
  第31回　日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-19K07182
[Presentation] Xanthine oxidaseおよび xanthine dehydrogenase活性における概日変動の検討2020
- Author(s)
  田山剛崇,喜多智生, 西村さとみ, 岡本友理香, 前田志津子, 杉原数美, 三宅勝志
- Organizer
  第30回日本医療薬学会
- Data Source
  KAKENHI-PROJECT-19K07182
[Presentation] マウス、ヒトに発現するAO タンパク質の分解系の同定2019
- Author(s)
  加藤真帆, 佐能正剛, 高岡尚輝, 大月佑也, 杉原数美, Mineko TERAO, Enrico GARATTINI, 太田茂, 古武弥一郎
- Organizer
  日本薬学会139年会　千葉幕張メッセ　2019年3月20-22日
- Data Source
  KAKENHI-PROJECT-17K08401
[Presentation] モリブデン含有薬物代謝酵素における概日リズムの検討2019
- Author(s)
  田山剛崇、前田志津子、岡村友理香、喜多智生、杉原数美、三宅勝志
- Organizer
  日本薬学会　第１４０年会
- Data Source
  KAKENHI-PROJECT-19K07182
[Presentation] 離乳期におけるラット肝CYPおよびaldehyde oxidaseの変動2019
- Author(s)
  杉原数美, 村川晃大, 荒井美幸, 田山剛崇, 清水良, 北村繁幸, 太田茂
- Organizer
  日本薬学会139年会　千葉幕張メッセ　2019年3月20-22日
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] Aldehyde oxidase およびCYP2A6 がnicotine 代謝に及ぼす影響2019
- Author(s)
  田山剛崇, 西村さとみ, 杉原数美, 北村繁幸, 佐和章弘, 三宅勝志
- Organizer
  日本薬学会139年会　千葉幕張メッセ　2019年3月20-22日
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] Aldehyde oxidase およびCYP2A6 がnicotine 代謝に及ぼす影響2019
- Author(s)
  田山剛崇, 西村さとみ, 杉原数美, 北村繁幸, 佐和章弘, 三宅勝志
- Organizer
  日本薬学会139年会　千葉幕張メッセ　2019年3月20-22日
- Data Source
  KAKENHI-PROJECT-17K08401
[Presentation] 離乳期におけるラット肝CYPおよびaldehyde oxidaseの変動2019
- Author(s)
  杉原数美, 村川晃大, 荒井美幸, 田山剛崇, 清水良, 北村繁幸, 太田茂
- Organizer
  日本薬学会139年会　千葉幕張メッセ　2019年3月20-22日
- Data Source
  KAKENHI-PROJECT-17K08401
[Presentation] Aldehyde oxidase低活性系統マウスでのAOX分子種の発現調節2019
- Author(s)
  津川　成樹、東　沙也香、吉村　彰恵、清水　良、佐能正剛，古武　弥一郎、北村　繁幸、太田　茂，杉原数美
- Organizer
  第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-17K08401
[Presentation] 薬物代謝酵素aldehyde oxidaseにおける概日リズムの検討2019
- Author(s)
  田山剛崇, 喜多智生, 西村さとみ, 前田志津子, 杉原数美, 佐和章弘, 三宅勝志
- Organizer
  第２９回　日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-19K07182
[Presentation] リン系難燃剤のラット肝および小腸カルボキシルエステラーゼに対する阻害効果2018
- Author(s)
  津越幸枝，渡部容子，杉原数美，北村繁幸
- Organizer
  フォーラム2018衛生薬学・環境トキシコロギー　アルカス佐世保　2018年9月10-11日
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] Assessment of inhibitory effects of drugs on mouse and human aldehyde oxidases through in silico, in vitro, and in vivo approaches2018
- Author(s)
  Naoki Takaoka, Seigo Sanoh, Katsuhiro Okuda, Go Sugahara, Ami Yanagi, Yuji Ishida, Chise Tateno, Yoshitaka Tayama, Kazumi Sugihara, Shigeyuki Kitamura, Mami Kurosaki, Mineko Terao, Enrico Garattini, Shigeru Ohta, Yaichiro Kotake
- Organizer
  2018 International Meeting on 22nd MDO and 33rd JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] Sex differences of aldehyde oxidases in mouse liverAssessment of inhibitory effects of drugs on mouse and human aldehyde oxidases through in silico, in vitro, and in vivo approaches2018
- Author(s)
  Kazumi Sugihara, Yoshitaka Tayama, Seigo Sanoh, Shigeyuki Kitamura, Shigeru Ohta
- Organizer
  2018 International Meeting on 22nd MDO and 33rd JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] Assessment of inhibitory effects of drugs on mouse and human aldehyde oxidases through in silico, in vitro, and in vivo approaches.2018
- Author(s)
  Naoki Takaoka, Seigo Sanoh, Katsuhiro Okuda, Go Sugahara, Ami Yanagi, Yuji Ishida, Chise Tateno, Yoshitaka Tayama, Kazumi Sugihara, Shigeyuki Kitamura, Mami Kurosaki, Mineko Terao, Enrico Garattini, Shigeru Ohta, Yaichiro Kotake
- Organizer
  2018 International Meeting on 22nd MDO and 33rd JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08401
[Presentation] Sex differences of aldehyde oxidases in mouse liver2018
- Author(s)
  Kazumi Sugihara, Yoshitaka Tayama, Seigo Sanoh, Shigeyuki Kitamura, Shigeru Ohta
- Organizer
  2018 International Meeting on 22nd MDO and 33rd JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08401
[Presentation] 臭素化難燃剤PBDE類によるAhRの活性化を介したUGT遺伝子発現誘導機構．内受容体PXRおよびCAR転写活性作用を示す甲状腺ホルモン構造類似環境化学物質のスクリーニング2017
- Author(s)
  清水　良，浦丸直人，渡部容子, 太田　茂, 北村繁幸, 杉原数美
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] Strain and sex differences of aldehyde oxidase isozymes in mouse liver2017
- Author(s)
  杉原数美、平本耕一、田坂真希、田山剛崇、佐能正剛、太田茂、北村繁幸
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-17K08401
[Presentation] 医薬品類による環境汚染と環境因子による毒性変動2017
- Author(s)
  杉原数美
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] 塩素消毒処理による医薬品および生活関連化学物質の毒性変動調査2017
- Author(s)
  國澤和憲、岡田達司、堂脇美緒、井上沙也香、清水　良、北村繁幸、太田　茂、杉原数美
- Organizer
  フォーラム2017：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] 薬物代謝酵素アルデヒドオキシダーゼのマウスにおける性差と系統差2017
- Author(s)
  岸沙也香、村川晃大、平本耕一、清水良、佐能正剛、太田茂、北村繁幸、杉原数美
- Organizer
  第56回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-17K08401
[Presentation] 薬物代謝酵素アルデヒドオキシダーゼのマウスにおける性差と系統差2017
- Author(s)
  岸沙也香、村川晃大、平本耕一、清水　良、佐能正剛、太田　茂、北村繁幸、杉原数美
- Organizer
  第56回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] マウス肝アルデヒドオキシダーゼの性特異的発現機序の検討2017
- Author(s)
  内藤祐子，田坂真希，富吉博也，濱﨑千尋，清水　良，佐能正剛，太田　茂，北村繁幸、杉原数美
- Organizer
  第56回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] マウス肝アルデヒド酸化酵素分子種の系統差と性差2017
- Author(s)
  杉原数美, 平本耕一, 田坂真希, 田山剛崇, 佐能正剛, 太田　茂, 北村繁幸
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] マウス肝アルデヒドオキシダーゼの性特異的発現機序の検討2017
- Author(s)
  内藤祐子、田坂真希、富吉博也、濱﨑千尋、清水　良、佐能正剛、太田　茂、北村繁幸、杉原数美
- Organizer
  第56回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-17K08401
[Presentation] リン系難燃剤のラットカルボキシルエステラーゼ活性に対する阻害効果2017
- Author(s)
  津越幸枝，渡部容子，杉原数美，北村繁幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] ロキソプロフェンナトリウム水和物細粒の飛散性に影響を与える因子の検討2016
- Author(s)
  土井えりか、手嶋茂貴、杉原数美、田山剛崇、三宅勝志
- Organizer
  第26回　日本医療薬学会年会
- Place of Presentation
  京都
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-16K08428
[Presentation] ロキソプロフェンナトリウム水和物細粒の飛散性に影響を与える因子の検討2016
- Author(s)
  前田志津子, 土井えりか, 手嶋茂貴, 杉原数美, 田山剛崇, 三宅勝志
- Organizer
  第26回日本医療薬学会年会
- Place of Presentation
  国立京都国際会館（京都市左京区）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-26460247
[Presentation] ラット肝、小腸及び膵臓ミクロソームのフタル酸エステルに対する加水分解活性の基質特異性2016
- Author(s)
  森口恭子，渡部容子，杉原数美，北村繁幸
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] タンニン酸アルブミンの製品間比較～帯電量調査～2016
- Author(s)
  前田志津子, 手嶋茂貴, 田山剛崇, 安原昌子, 寺重隆視, 杉原数美,佐和章弘, 三宅勝志
- Organizer
  日本薬学会第 136年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26460247
[Presentation] Allopurinol代謝に及ぼす投与量の影響2016
- Author(s)
  田山剛崇，杉原数美，三宅勝志，北村繁幸，太田　茂
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 臭素化難燃剤のPBDEおよびその代謝物による肝UGT遺伝子発現への影響2016
- Author(s)
  清水　良，浦丸直人，渡部容子，太田　茂，北村繁幸，杉原数美
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 患者の残薬管理および廃棄活動に関する調査2016
- Author(s)
  杉原数美、前田志津子、田山剛崇、西村和之、太田茂
- Organizer
  日本薬学会第 136年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26460247
[Presentation] リン系難燃剤のラット肝カルボキシルエステラーゼ活性に対する阻害効果2015
- Author(s)
  渡部容子，井上智賀，谷川悠華，浦丸直人，杉原数美，小島弘幸，北村繁幸
- Organizer
  フォーラム2015 衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 先発医薬品と後発医薬品の比較：ロキソプロフェンナトリウム水和物細粒の飛散粉じん量調査2015
- Author(s)
  前田　志津子、土井　えりか、杉原　数美、田山　剛崇、塚本　豊久
- Organizer
  日本薬学会第135年会
- Place of Presentation
  デザイン・クリエイティブセンター神戸（神戸市中央区）
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-26460247
[Presentation] Allopurinol代謝におけるaldehyde oxidase活性の寄与に関する検討2014
- Author(s)
  田山剛崇,杉原数美,三宅勝志,北村繁幸,太田　茂
- Organizer
  日本薬学会　第１３４年回
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25460235
[Presentation] 医薬品類による水環境汚染と生態毒性2013
- Author(s)
  杉原数美ら
- Organizer
  フォーラム2013 衛生薬学・環境トキシコロジー
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 新生児期甲状腺ホルモン撹乱の影響-成体期肝遺伝子発現変化-2013
- Author(s)
  中村直樹, 佐能正剛, 松原加奈, 杉原数美, 浦丸直樹, 北村繁幸, 宮川信一, 井口泰泉, 藤本成明, 太田茂
- Organizer
  フォーラム2013衛生薬学・環境トキシコロジー
- Place of Presentation
  九州大学(福岡)
- Data Source
  KAKENHI-PROJECT-23390030
[Presentation] 新生児期甲状腺ホルモン撹乱の影響-成体期肝遺伝子発現変化-2013
- Author(s)
  中村直樹、佐能正剛、松原加奈、杉原数美、浦丸直人、北村繁幸、宮川信一、井口泰泉、藤本成明、太田茂
- Organizer
  フォーラム2013衛生薬学・環境トキシコロジー
- Place of Presentation
  九州大学（福岡）
- Data Source
  KAKENHI-PROJECT-23390030
[Presentation] Allopurinol 代謝におけるxanthine oxidase および aldehyde oxidaseの関与2013
- Author(s)
  田山武崇, 杉原数美, 三宅勝志, 北村繁幸, 太田茂
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] ヒト肝細胞移植キメラマウスを用いたアロメトリックスケーリングによるヒト体内動態予測性評価2013
- Author(s)
  藤本真美、佐能正剛、成富洋一、佐藤公也、河村章生、堀口彩、杉原数美、北村繁幸、堀江透、立野知世、太田茂
- Organizer
  日本薬物動態学会　第28回年会
- Place of Presentation
  タワーホール船堀(東京）
- Data Source
  KAKENHI-PROJECT-23390030
[Presentation] 穀物によるマウス肝薬物代謝酵素の変動2013
- Author(s)
  清水良, 山口雅史, 浦丸直人, 黒木広明, 北村繁幸, 太田茂, 杉原数美
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] ヒト肝細胞移植キメラマウスを用いたアロメトリックスケーリングによるヒト体内動態予測性評価2013
- Author(s)
  藤本真美, 佐能正剛, 成富洋一, 佐藤公也, 河村章生, 堀口彩, 杉原数美, 北村繁幸, 堀江透, 立野知世, 太田茂
- Organizer
  日本薬物動態学会第28回年会
- Place of Presentation
  タワーホール船堀(東京)
- Data Source
  KAKENHI-PROJECT-23390030
[Presentation] ヒト・マウスにおけるアルデヒドオキシダーゼの代謝活性と基質特異性の比較2013
- Author(s)
  小原裕月, 佐能正剛, 杉原数美, 岸野貴大, 田山武崇, 浦丸直人, 立野知世, 北村繁幸, 太田茂
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Predictability of plasma concentration-time profiles in humans using chimeric mice with humanized liver2013
- Author(s)
  Sanoh S, Fujimoto N, Naritomi Y, Sato K, Kawamura A, Horiguchi A, Sugihara K, Kitamura S, Horie T, Tateno C, Ohta S
- Organizer
  10th International ISSX meeting
- Place of Presentation
  Toronto(Canada)
- Data Source
  KAKENHI-PROJECT-23390030
[Presentation] Sex differences of aldehyde oxidases in mouse liver2013
- Author(s)
  Kazumi Sugihara et al.
- Organizer
  日本薬物動態学会第２８回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] ヒト肝細胞移植キメラマウスにおけるアロメトリックスケーリングを用いたヒト体内動態予測の検証2013
- Author(s)
  藤本真美, 佐能正剛, 成富洋一, 佐藤公也, 河村章生, 堀口彩, 杉原数美, 立野知世, 堀江透, 北村繁幸, 太田茂
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Predictability of plasma concentration-time profiles in humans using chimeric mice with humanized liver2013
- Author(s)
  Sanoh S, Fujimoto M, Naritomi Y, Sato K, Kawamura A, Horiguchi A, Sugihara K, Kitamura S, Horie T, Tateno C, Ohta S.
- Organizer
  10th International ISSX meeting
- Place of Presentation
  Toronto (Canada)
- Data Source
  KAKENHI-PROJECT-23390030
[Presentation] PCB および PBDE の水酸化代謝物のヨードチロシン脱ヨウ素化酵素阻害作用2013
- Author(s)
  山頭征岳, 佐能正剛, 杉原数美, 江尻洋子, 堀江透, 北村繁幸, 太田茂
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] アセトアミノフェンおよびスリンダクの水環境中における光分解物の同定2013
- Author(s)
  川畑公平, 尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Effect of UV irradiation on the ecotoxicity of pharmaceuticals in aquatic environment2012
- Author(s)
  Kawabata K., Ogawa Y., Sugihara K., Sanoh S., Kitamura S., Ohta S.
- Organizer
  The 6th International Congress of Asian Society of Toxicology
- Place of Presentation
  Sendai, Japan
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 水環境中医薬類の太陽光・紫外線による毒性変動2012
- Author(s)
  川畑公平, 尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  第39回日本毒性学会学術年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 食餌がマウス肝薬物代謝酵素に及ぼす影響の1H-NMR メタボローム解析2012
- Author(s)
  杉原数美, 佐光華佳, 田上加苗, 三間昭平, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] ヒト肝細胞移植マウスを用いたイブプロフェンの代謝、血中動態の予測2012
- Author(s)
  佐能正剛、堀口彩、杉原数美、浦丸直人、立野知世、堀江透、北村繁幸、太田茂
- Organizer
  日本薬学会132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23390030
[Presentation] Prediction of human pharmacokinetics by allometric scaling using chimeric mice with humanized liver2012
- Author(s)
  Sanoh S., Naritomi Y., Sato K., Kawamura A., Horiguchi A., Sugihara K., Tateno C., Horie T., Kitamura S., Ohta S
- Organizer
  19th International Symposium on Microsomes and Drug Oxidations 12th European Regional ISSX Meeting
- Place of Presentation
  Noordwijk aan Zee, Netherlands
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 環境化学物質の転写活性化を介した甲状腺ホルモン撹乱作用2012
- Author(s)
  松原加奈, 佐能正剛, 藤本成明, 杉原数美, 北村繁幸, 太田茂
- Organizer
  日本薬学会132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23390030
[Presentation] ヒト肝細胞移植マウスを用いたイブプロフェンの代謝, 血中動態の予測2012
- Author(s)
  佐能正剛, 堀口彩, 杉原数美, 浦丸直人, 立野知世, 堀江透, 北村繁幸, 太田茂
- Organizer
  日本薬学会132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23390030
[Presentation] 食餌がマウス肝薬物代謝酵素に及ぼす影響の1H-NMRメタボローム解析,2012
- Author(s)
  杉原数美ら
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] ヒト・マウス・ヒト肝キメラマウスにおけるアルデヒドオキシダーゼの酵素活性の比較2012
- Author(s)
  小原裕月, 佐能正剛, 杉原数美, 岸野貴大, 田山剛崇, 浦丸直人, 立野知世, 北村繁幸, 太田茂
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 釜山市(大韓民国)の市街地を流域とする温泉川での医薬品汚染調査2012
- Author(s)
  杉原数美、川畑公平、Moon Jeon-Ok, 佐能正剛、北村繁幸、太田茂
- Organizer
  第46回日本水環境学会年会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 62 種生薬エキスの Ah レセプター結合活性の評価2012
- Author(s)
  杉原数美, 渡部容子, 北村繁幸, 原田亜紀子, 太田茂, 山路誠一
- Organizer
  第29回和漢医薬学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 62種生薬エキスのAhレセプター結合活性の評価2012
- Author(s)
  杉原数美ら
- Organizer
  第29回和漢医薬学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 環境科学物質による甲状腺ホルモン撹乱作用の in vitro および in vivo 評価2012
- Author(s)
  松原加奈, 中村直樹, 佐能正剛, 杉原数美, 浦丸直人, 北村繁幸, 宮川信一, 井口泰泉, 藤本成明, 太田茂
- Organizer
  フォーラム 2012 衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] ラット肝細胞スフェロイドにおける蛍光プローブを用いたアセトアミノフェン、ジクロフェナクによる肝毒性評価2012
- Author(s)
  山頭征岳, 佐能正剛, 杉原数美, 江尻洋子, 堀江透, 北村繁幸, 太田茂
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] ヒト肝細胞移植キメラマウスにおけるアロメトリックスケーリングを用いたヒト血中動態予測性の検証2012
- Author(s)
  藤本真美, 佐能正剛, 成富洋一, 佐藤公也, 河村章生, 堀口彩, 杉原数美, 立野知世, 堀江透, 北村繁幸, 太田茂
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 環境化学物質による甲状腺ホルモン撹乱作用のin vitro、in vivo評価2012
- Author(s)
  松原加奈、中村直樹、佐能正剛、杉原数美、浦丸直人、北村繁幸、宮川信一、井口泰泉、藤本成明、太田茂
- Organizer
  フォーラム2012 衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23390030
[Presentation] 環境化学物質による甲状腺ホルモン撹乱作用のin vitro, in vivo 評価2012
- Author(s)
  松原加奈, 中村直樹, 佐能正剛, 杉原数美, 浦丸直樹, 北村繁幸, 宮川信一, 井口泰泉, 藤本成明, 太田茂
- Organizer
  フォーラム2012衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23390030
[Presentation] アセトアミノフェンの水環境中における光分解と光毒性2012
- Author(s)
  川畑公平, 尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  フォーラム 2012 衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] ポテンシャルマップを用いた生活排水流入河川の医薬品汚染濃度予測2011
- Author(s)
  杉原数美、尾川雄一、川畑公平、佐能正剛、北村繁幸、西嶋渉、太田茂
- Organizer
  第45回日本水環境学会年会
- Place of Presentation
  札幌市(北海道大学)
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 釜山市街を流域とする中規模河川の医薬品汚染調査2011
- Author(s)
  杉原数美、川畑公平、Moon Jeon-Ok, 佐能正剛、北村繁幸、太田茂
- Organizer
  フォーラム2011 :衛生薬学・環境トキシコロジーシンポジウム
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 大韓民国釜山市温泉川の医薬品汚染調査2011
- Author(s)
  杉原数美、川畑公平、Mon Jyoun、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市(グランシップ静岡など)
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 釜山市街を流域とする中規模河川の医薬品汚染調査2011
- Author(s)
  杉原数美、川畑公平、Moon Jeon-Ok, 太田茂
- Organizer
  フォーラム2011・衛生薬学・環境トキシコロジーシンポジウム
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 大韓民国釜山市温泉川の医薬品汚染調査2011
- Author(s)
  杉原数美、川畑公平、Mon Jyoun、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 大韓民国釜山市温泉川の医薬品汚染調査2011
- Author(s)
  杉原数美, ら
- Organizer
  第131回日本薬学会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 環境化学物質の甲状腺ホルモン攪乱作用in vitro評価2011
- Author(s)
  松原加奈, 佐能正剛, 藤本成明, 浦丸直人, 杉原数美, 北村繁幸, 太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 紫外線照射による水環境中医薬品類の分解および水生生物への毒性変動調査2011
- Author(s)
  川畑公平、杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 紫外線照射による水環境中医薬品類の分解および水生生物への毒性変動調査2011
- Author(s)
  川畑公平、杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市(グランシップ静岡など)
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 大韓民国釜山市温泉川の医薬品汚染調査2011
- Author(s)
  杉原数美、川畑公平、Mon Jyoun、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市(グランシップ静岡など)
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] Prediction of PK parameters of human using human chimeric mice2011
- Author(s)
 Sanoh S, Horiguchi A, Sugihara K, Tateno C, Horie T, Kitamura S, Ohta S
- Organizer
 17^<th> International Society for the Study of Xenobiotics North American Meeting
- Place of Presentation
 Atlanta, Georgia, USA
- Year and Date
 2011-10-17
- Data Source
 KAKENHI-PROJECT-23390030
[Presentation] ヒト肝キメラマウスを用いたイブプロフェンのキラル変換2011
- Author(s)
  堀口彩, 佐能正剛, 杉原数美, 立野知世, 堀江透, 北村繁幸, 太田茂
- Organizer
  第26回日本薬物動態学会
- Place of Presentation
  広島
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-23390030
[Presentation] Prediction of PK parameters of human using human chimeric mice2011
- Author(s)
  Sanoh S, Horiguchi A, Sugihara K, Tateno C, Horie T, Kitamura S, Ohta S
- Organizer
  17th International Society for the Study of Xenobiotics North American Meeting
- Place of Presentation
  Atlanta, Georgia, USA
- Year and Date
  2011-10-17
- Data Source
  KAKENHI-PROJECT-23390030
[Presentation] 薬物代謝酵素の成長に伴う発達と食餌の影響.Developmental changes of drug-metabolizing enzymes and effect of dietary constituents in rats and mice2011
- Author(s)
  杉原数美, ら
- Organizer
  第26回日本薬物動態学会年会(シンポジュウム)
- Place of Presentation
  広島(招待講演)
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 大韓民国釜山市温泉川の医薬品汚染調査2011
- Author(s)
  杉原数美, 他
- Organizer
  第131回日本薬学会
- Place of Presentation
  静岡市
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] ポテンシャルマップを用いた生活排水流入河川の医薬品汚染濃度予測2011
- Author(s)
  杉原数美、尾川雄一、川畑公平、佐能正剛、北村繁幸、西嶋渉、太田茂
- Organizer
  第45回日本水環境学会年会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 医薬品等の特定汚染源物質による河川汚染濃度予測マップツールの作成2011
- Author(s)
  内田博久, 川畑公平, 尾川雄一, 佐能正剛, 北村繁幸, 太田茂, 杉原数美
- Organizer
  フォーラム2011 :衛生薬学・環境トキシコロジーシンポジウム
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] ヒトおよびラット肝キメラマウスを用いた医薬品の代謝プロファイルの予測2011
- Author(s)
  佐能正剛, 堀口彩, 杉原数美, 立野知世, 堀江透, 北村繁幸, 太田茂
- Organizer
  第38回日本トキシコロジー学会学術年会
- Place of Presentation
  横浜
- Year and Date
  2011-07-11
- Data Source
  KAKENHI-PROJECT-23390030
[Presentation] ポテンシャルマップを用いた生活排水流入河川の医薬品汚染濃度予測2011
- Author(s)
  杉原数美、尾川雄一、川畑公平、佐能正剛、北村繁幸、西嶋渉、太田茂
- Organizer
  第45回日本水環境学会年会
- Place of Presentation
  札幌市(北海道大学)
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 医薬品等の特定汚染源物質による河川汚染濃度予測マップツールの作成2011
- Author(s)
  内田博久, 川畑公平, 尾川雄一, 佐能正剛, 北村繁幸, 太田茂, 杉原数美
- Organizer
  フォーラム2011:衛生薬学・環境トキシコロジーシンポジウム
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 新生仔期ラットへの甲状腺ホルモン様物質曝露による影響評価2011
- Author(s)
  松原加奈, 佐能正剛, 藤本成明, 杉原数美, 北村繁幸, 太田茂
- Organizer
  フォーラム2011衛生薬学・環境トキシコロジー
- Place of Presentation
  金沢
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-23390030
[Presentation] 水環境中医薬品類の紫外線による分解と毒性変動2011
- Author(s)
  川畑公平、杉原数美、太田茂
- Organizer
  フォーラム2011・衛生薬学・環境トキシコロジーシンポジウム
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 紫外線照射による水環境中医薬品類の分解および水生生物への毒性変動調査2011
- Author(s)
  川畑公平、杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市(グランシップ静岡など)
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 環境化学物質の甲状腺ホルモン撹乱作用in vitro評価2011
- Author(s)
  松原加奈, 佐能正剛, 藤本成明, 浦丸直人, 杉原数美, 北村繁幸, 太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市(要旨発表)
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 下水道未整備地域河川での医薬品汚染ポテンシャルマップを用いた汚染予測と流域住民の環境保全意識調査2010
- Author(s)
  秋吉里絵, 古道律子, 宗重美恵子, 杉原数美, 尾川雄一, 川畑公平, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京都(星薬科大学)
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 水環境中医薬品の紫外線による分解物生成と水棲生物毒性変動2010
- Author(s)
  尾川雄一, 杉原数美, 川畑公平, 佐光華佳, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  日本トキシコロジー学会
- Place of Presentation
  宜野湾市(沖縄コンベンションセンター)
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 生活排水流入河川の生活関連物質汚染と流域住民への環境保全意識調査2010
- Author(s)
  秋吉里絵、古道律子、宗重美恵子、尾川雄一、川畑公平、佐能正剛、太田茂、杉原数美
- Organizer
  第49回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  米子市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 水環境中医薬品の紫外線による分解物生成と水棲生物毒性変動2010
- Author(s)
  尾川雄一, 杉原数圭, 川畑公平, 佐光華佳, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  日本トキシコロジー学会
- Place of Presentation
  宜野湾市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010
- Author(s)
  松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京都(星薬科大学)
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 環境化学物質のproteindisulfide isomerase(PDI)への結合による内分泌系に対する影響2010
- Author(s)
  佐能正剛, 松原加奈, 岩瀬恵理, 今岡進, 岡田和嗣, 浦丸直人, 藤本成明, 杉原数美, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生薬学・環境トキシコロジー
- Place of Presentation
  東京
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 水環境中医薬品の紫外線による分解物生成と水棲生物毒性変動2010
- Author(s)
  尾川雄一, 杉原数美, 川畑公平, 佐光華佳, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  日本トキシコロジー学会
- Place of Presentation
  宜野湾市(沖縄コンベンションセンター)
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 生活排水流入河川の生活関連物質汚染と流域住民への環境保全意識調査2010
- Author(s)
  秋吉里絵、古道律子、宗重美恵子、尾川雄一、川畑公平、佐能正剛、太田茂、杉原数美
- Organizer
  第49回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  米子市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] インドネシア・スラバヤ市スラバヤ川の医薬品汚染調査～アイルランガ大学との共同調査～2010
- Author(s)
  杉原数美1, 尾川雄一, 佐光華佳, M.Yuwano, A.H.Syahrani, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京都(星薬科大学)
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 下水道未整備地域河川での医薬品汚染ポテンシャルマップを用いた汚染予測と流域住民の環境保全意識調査2010
- Author(s)
  秋吉里絵, 古道律子, 宗重美恵子, 杉原数美, 尾川雄一, 川畑公平, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京都(星薬科大学)
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] インドネシア・スラバヤ市スラバヤ川の医薬品汚染調査～アイルランガ大学との共同調査～2010
- Author(s)
  杉原数美1, 尾川雄一, 佐光華佳, M.Yuwano, A.H.Syahrani, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京都(星薬科大学)
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 環境中における甲状腺ホルモン撹乱物質のスクリーニング2010
- Author(s)
  佐能正剛, 岩瀬恵理, 松原加奈, 杉原数美, 浦丸直人, 藤本成明, 北村繁幸, 太田茂
- Organizer
  第130回日本薬学会年会
- Place of Presentation
  岡山市
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010
- Author(s)
  松原加奈,佐能正剛,岩瀬恵理,藤本成明,浦丸直人,杉原数美,加藤善久,北村繁幸,太田茂
- Organizer
  フォーラム2010衛生環境トキわシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 生活排水流入モデル河川における医薬品環境負荷予測2010
- Author(s)
  尾川雄一、杉原数美、川畑公平、佐光華佳、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 生活排水流入モデル河川における医薬品環境負荷予測2010
- Author(s)
  尾川雄一、杉原数美、川畑公平、佐光華佳、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 広島県内保険薬局を対象とした医薬品廃棄に関するパイロット調査2010
- Author(s)
  杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 広島県内保険薬局を対象とした医薬品廃棄に関するパイロット調査2010
- Author(s)
  杉原数美, 尾川雄一, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 生活排水流入モデル河川における医薬品環境負荷予測2010
- Author(s)
  尾川雄一、杉原数美、川畑公平、佐光華佳、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 下水道未整備地域河川での医薬品汚染ポテンシャルマップを用いた汚染予測と流域住民の環境保全意識調査,フォーラム2010衛生環境トキシコロジー2010
- Author(s)
  秋吉里絵, 古道律子, 宗重美恵子, 杉原数美, 尾川雄一, 川畑公平, 佐能正剛, 北寸繁太田
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 黒瀬川の水質汚染調査報告2010
- Author(s)
  杉原数美
- Organizer
  平成22年度東広島市公衆衛生協議会総会
- Place of Presentation
  東広島市
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010
- Author(s)
  松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京都(星薬科大学)
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 環境中における甲状腺ホルモン撹乱物質のスクリーニング2010
- Author(s)
  佐能正剛, 岩瀬恵理, 松原加奈, 杉原数美, 浦丸直人, 藤本成明, 北村繁幸, 太田茂
- Organizer
  130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 環境化学物質甲状腺ホルモン作用の高感度レポータージーンアッセイ2010
- Author(s)
  松原加奈, 藤本成明, 佐能正剛, 杉原数美, 北村繁幸, 太田茂
- Organizer
  環境ホルモン学会第13回研究発表会
- Place of Presentation
  東京
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 生活排水流入河川での医薬品による水汚染調査2010
- Author(s)
  杉原数美、尾川雄一、川畑公平、佐光華佳、佐能正剛、太田茂、西嶋渉、北村繁幸
- Organizer
  第44回日本水環境学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 環境化学物質のProtein Disulfide Isomerase(PDI)への結合による内分泌系に対する影響2010
- Author(s)
  佐能正剛, 松原加奈, 岩瀬恵理, 今岡進, 岡田和嗣, 浦丸直人, 藤本成明, 杉原数美, 北村繁幸, 太田茂
- Organizer
  衛生薬学・環境トキシコロジーフォーラム2010
- Place of Presentation
  東京都
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 生活排水流入河川での医薬品による水汚染調査2010
- Author(s)
  杉原数美, 尾川雄一, 川畑公平, 佐光華佳, 佐能正剛, 太田茂, 西嶋渉, 北村繁幸
- Organizer
  第44回日本水環境学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 広島県内保険薬局を対象とした医薬品廃棄に関するパイロット調査2010
- Author(s)
  杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] ,広島県内保険薬局を対象とした医薬品廃棄に関するパイロット調査2010
- Author(s)
  杉原数美、尾川雄一、佐能正剛、北村繁幸,太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 下水道未整備地域河川での医薬品汚染ポテンシャルマップを用いた汚染予測と流域住民の環境保全意識調査2010
- Author(s)
  秋吉里絵,古道律子,宗重美恵子,杉原数美,尾川雄一,川畑公平,佐能正剛,北村繁幸,太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 黒瀬川の水質汚染調査報告2010
- Author(s)
  杉原数美
- Organizer
  平成22年度東広島市公衆衛生協議会総会
- Place of Presentation
  東広島市(福富道の駅)
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] インドネシア・スラバヤ川の医薬品汚染調査-アイルランガ大学との共同調査2010
- Author(s)
  杉原数美, 他
- Organizer
  フォーラム2010:衛生薬学・環境トキシコロギー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 黒瀬川の水質汚染調査報告2010
- Author(s)
  杉原数美
- Organizer
  平成22年度東広島市公衆衛生協議会総会
- Place of Presentation
  東広島市
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010
- Author(s)
  松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] インドネシア・スラバヤ市スラバヤ川の医薬品汚染調査～アイルランガ大学との共同調査～2010
- Author(s)
  杉原数美, 尾川雄一, 佐光華佳, Yuwano, A. H. Syahrani, M.佐能正剛, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 生活排水流入河川の生活関連物質汚染と流域住民への環境保全意識調査2010
- Author(s)
  秋吉里絵、古道律子、宗重美恵子、尾川雄一、川畑公平、佐能正剛、太田茂、杉原数美
- Organizer
  第49回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  米子市(米子コンベンションセンター)
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010
- Author(s)
  松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
- Organizer
  衛生薬学・環境トキシコロジーフォーラム2010
- Place of Presentation
  東京都
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 黒瀬川の水質汚染調査報告2010
- Author(s)
  杉原数美
- Organizer
  平成22年度東広島市公衆衛生協議会総会
- Place of Presentation
  東広島市(福富道の駅)
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 環境化学物質甲状腺ホルモン作用の高感度レポータージーンアッセイ2010
- Author(s)
  松原加奈, 藤本成明, 佐能正剛, 杉原数美, 北村繁幸, 太田茂
- Organizer
  環境ホルモン学会第13回研究発表会
- Place of Presentation
  東京都
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 水環境中医薬品の紫外線による分解物生成と水棲生物毒性変動2010
- Author(s)
  尾川雄一,杉原数美,川畑公平,佐光華佳,佐能正剛,北村繁幸,太田茂
- Organizer
  日本トキシコロジー学会
- Place of Presentation
  宜野湾市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 生活排水流入モデル河川における医薬品環境負荷予測2010
- Author(s)
  尾川雄一, 杉原数美, 川畑公平, 佐光華佳, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] インドネシア・スラバヤ市スラバヤ川の医薬品汚染調査～アイルランガ大学との共同調査～2010
- Author(s)
  杉原数美,尾川雄一,佐光華佳,M.Yuwano, A.H.Syahrani,佐能正剛,北村繁幸,太田茂
- Organizer
  フォーラム2010衛生環境トキわシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010
- Author(s)
  松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生薬学・環境トキシコロジー
- Place of Presentation
  東京
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 生活排水流入河川の生活関連物質汚染と流域住民への環境保全意識調査2010
- Author(s)
  秋吉里絵、古道律子、宗重美恵子、尾川雄一、川畑公平、佐能正剛、太田茂、杉原数美
- Organizer
  第49回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  米子市(米子コンベンションセンター)
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 生活排水流入河川流域の医薬品汚染ポテンシャルマップ-モデル河川黒瀬川での調査-2009
- Author(s)
  杉原数美, 尾川雄一, 佐光華佳, 佐能正剛, 清水良, 北村繁幸, 太田茂
- Organizer
  フォーラム衛生薬学・環境トキシコロジー
- Place of Presentation
  沖縄県宜野湾市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 水環境中医薬品類の紫外線による分解と非意図的生成物の分析2009
- Author(s)
  尾川雄一,杉原数美,佐能正剛,北村繁幸,久保光志,太田茂
- Organizer
  フォーラム衛生薬学・環境トキシコロジー
- Place of Presentation
  宜野湾市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 環境化学物質の甲状腺ホルモン受容体結合活性とその代謝変動2009
- Author(s)
  佐能正剛, 岩瀬恵理, 杉原数美, 加藤善久, 浦丸直人, 藤本成明, 北村繁幸, 太田茂
- Organizer
  環境ホルモン学会第12回研究発表会
- Place of Presentation
  東京
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] ヒト肝キメラマウスを用いたヒト薬物代謝・動態予測2009
- Author(s)
  杉原数美, 井上多恵, 田上千秋, 堀口彩, 佐能正剛, 立野知世, 堀江透, 北村繁幸, 太田茂
- Organizer
  日本薬物動態学会第24回年会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 臭素化難燃剤PBDEの甲状腺ホルモン受容体結合活性の代謝による変動2009
- Author(s)
  岩瀬恵理, 小島弘幸, 杉原数美, 浦丸直人, 藤本成明, 黒木広明, 北村繁幸, 太田茂
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] ヒト肝キメラマウスを用いたヒト薬物代謝・動態予測2009
- Author(s)
  杉原数美, 井上多恵, 田上千秋, 堀口彩, 佐能正剛, 立野知世, 堀江透, 北村繁幸, 太田茂
- Organizer
  日本薬物動態学会第24回年会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] HYDROXYLATED POLYBROMINATED DIPHENYL ETHERS INTERRACT WITH THYROID HORMONE AND ESTROGEN RECEPTORS2009
- Author(s)
  Sugihara K, Kitamura S, Shinohara S, Iwase E, Uramaru N, Shigematsu H, Fujimoto N, Ohta S
- Organizer
  DIOXIN2009
- Place of Presentation
  北京市、中華人民共和国
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 生活排水流入河川流域の医薬品汚染ポテンシャルマップーモデル河川黒瀬川での調査一2009
- Author(s)
  杉原数美, 尾川雄一, 佐光華佳, 佐能正剛, 清水良, 北村繁幸, 太田茂
- Organizer
  フォーラム衛生薬学・環境トキシコロジー
- Place of Presentation
  宜野湾市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 生活排水流入河川流域の医薬品汚染ポテンシャルマップ-モデル河川黒瀬川での調査-2009
- Author(s)
  杉原数美, 尾川雄一, 佐光華佳, 佐能正剛, 清水良, 北村繁幸, 太田茂
- Organizer
  フォーラム衛生薬学・環境トキシコロジー
- Place of Presentation
  沖縄県宜野湾市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 環境化学物質の甲状腺ホルモン受容体結合活性とその代謝変動2009
- Author(s)
  佐能正剛, 岩瀬恵理, 杉原数美, 加藤善久, 浦丸直人, 藤本成明, 北村繁幸, 太田茂
- Organizer
  環境ホルモン学会第12回研究発表会
- Place of Presentation
  東京都
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] HYDROXYLATED POLYBROMINATED DIPHENYL ETHERS INTERRACT WITH THYROID HORMONE AND ESTROGEN RECEPTORS2009
- Author(s)
  Sugihara K, Kitamura S, Shinohara S, Iwase E, Uramaru N, Shigematsu H, Fujimoto N and Ohta S
- Organizer
  DIOXIN2009
- Place of Presentation
  北京市、中華人民共和国
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 生活排水流入河川流域の医薬品汚染ポテンシャルマップ-モデル河川黒瀬川での調査-2009
- Author(s)
  杉原数美,尾川雄一,佐光華佳,佐能正剛,清水良,北村繁幸,太田茂
- Organizer
  フォーラム衛生薬学・環境トキわシコロジー
- Place of Presentation
  宜野湾市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 水環境中医薬品類の紫外線による分解と非意図的生成物の分析2009
- Author(s)
  尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 久保光志, 太田茂
- Organizer
  フォーラム衛生薬学・環境トキシコロジー
- Place of Presentation
  沖縄県宜野湾市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] HYDROXYLATED POL YBROMINATED DIPHENYL ETHERS INTERRACT WITH THYROID HORMONE AND ESTROGEN RECEPTORS2009
- Author(s)
  Sugihara K, Kitamura S, Shinohara S, Iwase E, Uramaru N, Shigematsu H, Fujimoto N, Ohta S
- Organizer
  DIOXIN2009
- Place of Presentation
  北京市、中華人民共和国
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 水環境中医薬品類の紫外線による分解と毒性変動2009
- Author(s)
  尾川雄一,杉原数美,佐能正剛,北村繁幸,久保光志,太田茂
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 水環境中医薬品類の紫外線による分解と非意図的生成物の分析2009
- Author(s)
  尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 久保光志, 太田茂
- Organizer
  フォーラム衛生薬学・環境トキシコロジー
- Place of Presentation
  沖縄県宜野湾市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 生活排水汚染水域の医薬品探索および環境動態の検討2008
- Author(s)
  尾川雄一,杉原数美,佐能正剛,北村繁幸,久保光志,太田茂
- Organizer
  フォーラム2008:衛生薬学・環境トキシコロジー
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 医薬品による環境汚染防止に向けての廃棄方法実態調査2008
- Author(s)
  杉原数美,尾川雄一,佐能正剛,北村繁幸,久保光志,太田茂
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 生活排水流入河川水および下水処理場流入・流出水中の医薬品探索2008
- Author(s)
  尾川雄一,杉原数美,佐能正剛,北村繁幸,久保光志,太田茂
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] Developmental changes of aldehyde oxidase activity in liver cytosol of young ehildren2007
- Author(s)
  Y., Tayama, K., Sugihara, S., Kitamura, S., Ohta
- Organizer
  8th International ISSX Meeting
- Place of Presentation
  Sendai Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] Chimeric mice with humanized liver as a model to predict diazepam metabolism in humans.2007
- Author(s)
  T., Inoue, K., Sugihara, S., Kitamura, H., Ohshita, T., Horie, S., Ohta
- Organizer
  8th International ISSX Meeting
- Place of Presentation
  Sendai Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] Screening of AhR-binding, estrogenic and antiandrogenic activities of benzophenone derivatives used as UV stabilizers and sunscreens2007
- Author(s)
  K., sugihara, S., Shinohara, T., Suzuki, N., Fujimoto, S., Kitamura, S., Ohta
- Organizer
  DIOXIN 2007
- Place of Presentation
  Tokyo Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] A Parkinson's disease-related neurotoxin binds to tubulin.2007
- Author(s)
  Ryuki, Kohta, Yaichiro, Kotake, Shunsuke, Izumi, Kazumi, Sugihara, Takamitsu, Hosoya, Toshiyuki, Hiramatsu, Yuko, Ohtsubo, Hiroko, Koyama, Masaaki, Suzuki, Shigeru, Ohta
- Organizer
  Neuro 2007
- Place of Presentation
  Yokohama
- Year and Date
  2007-09-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390037
[Presentation] In vivo and in vitro metabolism of zaleplon in chimeric mice with humanized liver2007
- Author(s)
  C., Tanoue, K., Sugihara, S., Kitamura, T., Inoue, T., Horie, S., Ohta
- Organizer
  8th, International ISSX Meeting
- Place of Presentation
  Sendai Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] A Parkinson's disease-related neurotoxin binds to tubulin2007
- Author(s)
  Ryuki, Kohta, Yaichiro, Kotake, Shunsuke, Izumi, Kazumi, Sugihara, Takamitsu, Hosoya, Toshiyuki, Hiramatsu, Yuko, Ohtsubo, Hiroko, Koyama, Masaaki, Suzuki, Shigeru, Ohta
- Organizer
  Neuro2007
- Place of Presentation
  Yokohama
- Year and Date
  2007-09-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18406004
[Presentation] Metabolism of carbamate pesticides by liver microsomes and plasma of human and rat2007
- Author(s)
  S., Tange, S., Kitamura, K., Sugihara, S., Ohta
- Organizer
  8th International ISSX Meeting
- Place of Presentation
  Sendai Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] Parabens and phthalates : Their metabolism, AhR ligand activity, estrogenic Activity, and P450-inhibitory activity2007
- Author(s)
  H., Oz-aki, S., Shinohara, S., Tange, K., Sugihara, S., Kitamura, S., Ohta
- Organizer
  DIOXIN 2007
- Place of Presentation
  Tokyo Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] Thyroid hormonal and estrogenic activity of OH-PCB and OH-PBDE in cell culture2007
- Author(s)
  S., Kitamura, T., Suzuki, K., Sugihara, N., Uramaru, H., Kuroki, N., Fujimoto, S., Ohta
- Organizer
  DIOXIN 2007
- Place of Presentation
  Tokyo Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] オス型成長ホルモン曝露がマウス肝癌細胞(Hepa 1-6)のaldehyde oxidasa発現に与える影響
- Author(s)
  藤田裕太郎，長島和也，堀川嫌太，清水　良，北村繁幸，太田　茂，杉原数美
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] Allopurinol代謝に及ぼすaldehyde oxidase活性の影響～ラットin vivoにおける検討～
- Author(s)
  田山剛高，杉原数美，三宅勝志，北村繁幸，太田茂
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 環境中医薬品類の塩素消毒による毒性発現
- Author(s)
  杉原数美，高田　鑑，増田莉奈，大上　凌，小林秀文，清水　良，北村繁幸，太田　茂
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  神戸
- Year and Date
  2014-07-02 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 医薬品の塩素処理による分解と変異原性発現
- Author(s)
  藤田哲孝，泉　哲平，三好晃史，清水　良，小林秀文，北村繁幸，太田　茂，杉原数美
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] Effects of metabolism of UV-absorbers by rat liver microsomes on their nuclear receptor activation.
- Author(s)
  Watanabe Y., Kojima H., Takeuchi S., Uramaru N., Sugihara K., Sanoh S., Ohta S., Kitamura S.
- Organizer
  DIOXIN 2014. The 34th International Symposium on Halogenated Persistent Organic Pollutants,
- Place of Presentation
  Madrid, Spain
- Year and Date
  2014-08-31 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] Characterization of human and mouse PXR- and CAR-mediated transcriptional activation by bisphenol A and its related compounds
- Author(s)
  Kojima H., Sanoh S., Takeuchi S., Sugihara K., Yoshinari K., Kitamura S.
- Organizer
  54th Annual Meeting and ToxExpo (Society of Toxicology)
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2015-03-22 – 2015-03-26
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] レポーターアッセイ系を用いた香粧品香料によるPXR、CAR、PPARおよびAhR活性の評価
- Author(s)
  渡部容子，小島弘幸，浦丸直人，藤本成明，杉原数美，吉成浩一，太田　茂，北村繁幸
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] マウス肝aldehyde oxidase発現への脳下垂体の影響
- Author(s)
  秋本有花，岡嵜明穂，増岡さゆり，濱岡裕美，清水　良，佐能正剛，太田　茂，北村繁幸，杉原数美
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 環境化学物質におけるカエル甲状腺ホルモン作用のアゴニストおよびアンタゴニスト活性
- Author(s)
  佐能正剛，中村直樹，鈴木賢一，柏木啓子，花田秀樹，山本　卓，新海　正，杉原数美，藤本成明，北村繁幸，柏木昭彦，太田　茂
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] Metabolic activation of cis- and trans- permethrine for estrogenic and anti-androgenic activities
- Author(s)
  Sugihara K.,Tange N., Fujimoto N., Uramaru N., Ohta S., Kitamura S.
- Organizer
  DIOXIN 2014. The 34th International Symposium on Halogenated Persistent Organic Pollutants,
- Place of Presentation
  Madrid, Spain
- Year and Date
  2014-08-31 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] アルデヒドオキシダーゼと薬物代謝・安全性研究
- Author(s)
  佐能正剛，田山剛高，杉原数美，北村繁幸，Mineko Terao，Enrico Garattini, 太田　茂
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  神戸
- Year and Date
  2014-07-02 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 薬物代謝酵素aldehyde oxidaseのマウス肝での性差発現と化学物質の影響
- Author(s)
  杉原数美，岡嵜明穂，秋本有花，田山剛高，前田志津子，佐能正剛，北村繁幸，太田　茂
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 香粧品香料のヒトおよびラットPXR、CAR、PPARa、AhRに対するアゴニスト活性
- Author(s)
  渡部容子，小島弘幸，浦丸直人，杉原数美, 吉成浩一, 太田　茂，北村繁幸．
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 核内受容体PXRおよびCAR転写活性に対する甲状腺ホルモン構造類似物質の影響
- Author(s)
  清水　良，渡部容子，浦丸直人，小島弘幸，武内伸治，黒木広明，太田　茂，北村繁幸，杉原数美
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] ラット in vivo におけるallopurinol代謝へのxanthine oxidase およびaldehyde oxidase活性の影響
- Author(s)
  田山剛崇、杉原数美、三宅勝志、北村繁幸、太田　茂
- Organizer
  第24回　日本医療薬学会年回
- Place of Presentation
  名古屋
- Year and Date
  2014-09-27 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-25460235
[Presentation] Allopurinol代謝に及ぼすaldehyde oxidase活性の影響～ラット in vivoにおける検討～
- Author(s)
  田山剛崇、杉原数美、三宅勝志、北村繁幸、太田　茂
- Organizer
  日本薬学会　第135年回
- Place of Presentation
  神戸
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460235

1. OHTA Shigeru (60160503)

# of Collaborated Projects: 21 results

# of Collaborated Products: 153 results
2. KITAMURA Shigeyuki (40136057)

# of Collaborated Projects: 20 results

# of Collaborated Products: 188 results
3. FUJIMOTO Nariaki (40243612)

# of Collaborated Projects: 9 results

# of Collaborated Products: 46 results
4. Tayama Yoshitaka (80389121)

# of Collaborated Projects: 7 results

# of Collaborated Products: 22 results
5. YOSHIHARA Shinichi (00037607)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
6. SANOH Seigo (00552267)

# of Collaborated Projects: 5 results

# of Collaborated Products: 24 results
7. KOTAKE Yaichiro (20335649)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
8. SHIMIZU RYOU (00570491)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
9. NISHIJIMA Wataru (20243602)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
10. KASHIWAGI Akihiko (50106796)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. WATANABE Hiromitu (00034653)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. URAMARU Naoto (90424069)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
13. TANIGUCHI Yoshihiko (30403520)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 渡部容子 (60628056)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
15. KOJIMA Hiroyuki (10414286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. MAEDA SHIZUKO (80435065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. NAKAMURA Shigenobu (30026843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. ARIZONO Koji (70128148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YAMASHITA Keisuke (40166666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TASHIRO Tomoko (50114541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 塚本豊久 (40389101)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. 佐和章弘 (70389104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 岡村友理香 (20645890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
24. 立花研 (10400540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TAKEUCHI Shinji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 今岡進

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 岡田和嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sugihara kazumi 杉原 数美

SUGIHARA Kazumi 杉原 数美

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Study of the effects of PPCPs on plant growth and construction of screening system for endrine disruptors of plantPrincipal Investigator

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Epigenetic regulation of sex-specific gene expression and investigation of the effects of environmental chemicals and drugsPrincipal Investigator

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Study of PPCPs in Eastern Asian countriesPrincipal Investigator

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Sugihara kazumi 杉原数美

SUGIHARA Kazumi 杉原数美