YOSHIMOTO Katsuhiko 吉元勝彦

… Alternative Names

吉元勝彦ヨシモトカツヒコ

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Researcher Number	20271257
Affiliation (based on the past Project Information) *help	2009 – 2012: 杏林大学, 医学部, 講師 2007: 杏林大学, 医学部, 講師
Review Section/Research Field	Except Principal Investigator Metabolomics
Keywords	Except Principal Investigator MCP-1 / 脂肪細胞 / 膵β細胞 / マクロファージ / 酸化ストレス / インスリン分泌 / 2型糖尿病 / アンカップリング / VEGF / 熱ショック蛋白 / サイトカイン / 膵ラ氏島

Elucidation of involved mechanisms for macrophage infiltration into pancreatic islets and of its role on the occurrence of type 2 diabetes.
- Principal Investigator
  
  ISHIDA Hitoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kyorin University
Elucidation of involved mechanisms impaired for insulin secretion due to oxidative stress and macrophages in pancreatic islets of type 2 diabetes.
- Principal Investigator
  
  ISHIDA Hitoshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kyorin University

All 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Induction of mitochondrial uncoupling enhances VEGF120 but reduces MCP-1 release in mature 3T3-L1 adipocytes: possible regulatory mechanism through endogenous ER stress and AMPK-related pathways.2012
- Author(s)
  K. Miyokawa-Gorin *, K. Takahashi *, K. Handa, A. Kitahara, Y. Sumitani, H. Katsuta, T. Tanaka, S. Nishida, K. Yoshimoto, H. Ohno, and H. Ishida.(*equally contributed)
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 419 Pages: 200-205
- Data Source
  KAKENHI-PROJECT-22590993
[Journal Article] Increased bone resorption may play a crucial role in the occurrence of osteopenia in patients with type 2 diabetes: possible involvement of accelerated polyol pathway in its pathogenesis.2008
- Author(s)
  M. Takizawa, K. Suzuki, T. Matsubayashi, M. Kikuyama, H. Suzuki, K. Takahashi, H. Katsuta, J. Mitsuhashi, S. Nishida, S. Yamaguchi, K. Yoshimoto, E. Itagaki, H. Ishida
- Journal Title
  
  Diabetes Res Clin Pract 82
  
  Pages: 119-126
- Data Source
  KAKENHI-PROJECT-19591065
[Journal Article] JNK-and IκB-dependent pathways regulate MCP-1, but not adiponectin, release from artificially hypertrophied 3T3-L1 adipocytes preloaded with palmitate in vitro.2008
- Author(s)
  K. Takahashi, S. Yamaguchi, T. Shimoyama, H. Seki, K. Miyokawa, H. Katsuta, T. Tanaka, K. Yoshimoto, H. Ohno, S. Nagamatsu, H. Ishida
- Journal Title
  
  Am J Physiol 294
- Data Source
  KAKENHI-PROJECT-19591065
[Journal Article] Enhanced release of monocyte chemoattractant protein-1 (MCP-1) by high glucose and free fatty acid and its underlying mechanism in MIN6βcells.2008
- Author(s)
  H. Seki, K. Takahashi, K. Miyokawa, K. Handa, H. Katsuta, S. Yamaguchi, K. Yoshimoto, E. Itagaki, S. Nagamatsu, H. Ishida
- Journal Title
  
  J Kyorin Med Soc 39
  
  Pages: 31-36
- Data Source
  KAKENHI-PROJECT-19591065
[Journal Article] Endogenous oxidative stress, but not ER stress, induces hypoxia-independent VEGF120 release through PI3K-dependent pathways in 3T3-L1 adipocytes.
- Author(s)
  K. Takahashi, K. Miyokawa-Gorin, K. Handa, A. Kitahara, R. Moriya, H. Onuma, Y. Sumitani, T. Tanaka, H. Katsuta, S. Nishida, K. Yoshimoto, H. Ohno and H. Ishida.
- Journal Title
  
  Obesity
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22590993
[Presentation] 温熱処理によるHSP72発現の増強と脂肪細胞由来炎症関連アディポカインの分泌動態の変化について2012
- Author(s)
  高橋和人,北原敦子,五林可織,半田桂子,森谷理恵,小沼裕寿,炭谷由計,田中利明,勝田秀紀,西田進,吉元勝彦,石田均
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590993
[Presentation] 脂肪細胞からのアディポネクチン分泌に及ぼすmitochondrial uncoupling の影響とその制御機構に関わる細胞内情報伝達系の検討2011
- Author(s)
  五林可織,高橋和人,半田桂子,北原敦子,炭谷由計,田中利明,勝田秀紀,西田進,吉元勝彦,板垣英二,石田均
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22590993
[Presentation] Hypoxia- independent VEGF120 secretion is stimulated by increase of endogenous oxidative stress through PI3K-dependent pathways in artificially hypertrophied 3T3-L1 adipocytes: The regulation by distinct mechanism from MCP-1 via JNK and p38 MAPK pathways2010
- Author(s)
  K. Takahashi, S. Yamaguchi, T. Shimoyama, T. Tanaka, K. Miyokawa, K. Handa, H. Katsuta, S. Nishida, K. Yoshimoto, H. Ishida
- Organizer
  14th International Congress of Endocrinology
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-19591065
[Presentation] 脂肪細胞のミトコンドリア内でのmetabolic couplingが細胞機能に果たす役割について2010
- Author(s)
  三代川可織,高橋和人,半田桂子,黒川三知子,森谷理恵,下山達宏,田中利明,勝田秀紀,山口真哉,吉元勝彦,石田均
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-22590993
[Presentation] 肥大化脂肪細胞におけるVEGF120分泌の制御機構について-MCP-1分泌機構との相違-2009
- Author(s)
  高橋和人, 山口真哉, 下山達宏, 田中利明, 三代川可織, 半田桂子, 勝田秀紀, 西田進, 吉元勝彦, 永松信哉, 石田均
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19591065
[Presentation] Glucolipotoxicityによる膵β細胞からのMCP-1分泌の増加と細胞内情報伝達系の関与2008
- Author(s)
  関博之, 高橋和人, 三代川可織, 半田桂子, 勝田秀紀, 下山達宏, 田中利明, 山口真哉, 吉元勝彦, 板垣英二, 永松信哉, 石田均
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591065
[Presentation] 膵β細胞からのMCP-1分泌に及ぼす高濃度グルコースおよび脂肪酸の影響について2007
- Author(s)
  関博之, 高橋和人, 伊藤英介, 勝田秀紀, 田中利明, 下山達宏, 山口真哉, 吉元勝彦, 永松信哉, 石田均
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19591065

1. ISHIDA Hitoshi (80212893)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. NAGAMATSU Shinya (80231489)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. INUKAI Kouichi (20333007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YOSHIMOTO Katsuhiko 吉元 勝彦

吉元 勝彦 ヨシモト カツヒコ

Research Projects

Research Products

Co-Researchers

Elucidation of involved mechanisms for macrophage infiltration into pancreatic islets and of its role on the occurrence of type 2 diabetes.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of involved mechanisms impaired for insulin secretion due to oxidative stress and macrophages in pancreatic islets of type 2 diabetes.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Induction of mitochondrial uncoupling enhances VEGF120 but reduces MCP-1 release in mature 3T3-L1 adipocytes: possible regulatory mechanism through endogenous ER stress and AMPK-related pathways.2012

Author(s)

Journal Title

Data Source

[Journal Article] Increased bone resorption may play a crucial role in the occurrence of osteopenia in patients with type 2 diabetes: possible involvement of accelerated polyol pathway in its pathogenesis.2008

Author(s)

Journal Title

Data Source

[Journal Article] JNK-and IκB-dependent pathways regulate MCP-1, but not adiponectin, release from artificially hypertrophied 3T3-L1 adipocytes preloaded with palmitate in vitro.2008

Author(s)

Journal Title

Data Source

[Journal Article] Enhanced release of monocyte chemoattractant protein-1 (MCP-1) by high glucose and free fatty acid and its underlying mechanism in MIN6βcells.2008

Author(s)

Journal Title

Data Source

[Journal Article] Endogenous oxidative stress, but not ER stress, induces hypoxia-independent VEGF120 release through PI3K-dependent pathways in 3T3-L1 adipocytes.

Author(s)

Journal Title

Data Source

[Presentation] 温熱処理によるHSP72発現の増強と脂肪細胞由来炎症関連アディポカインの分泌動態の変化について2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 脂肪細胞からのアディポネクチン分泌に及ぼすmitochondrial uncoupling の影響とその制御機構に関わる細胞内情報伝達系の検討2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Hypoxia- independent VEGF120 secretion is stimulated by increase of endogenous oxidative stress through PI3K-dependent pathways in artificially hypertrophied 3T3-L1 adipocytes: The regulation by distinct mechanism from MCP-1 via JNK and p38 MAPK pathways2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 脂肪細胞のミトコンドリア内でのmetabolic couplingが細胞機能に果たす役割について2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 肥大化脂肪細胞におけるVEGF120分泌の制御機構について-MCP-1分泌機構との相違-2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Glucolipotoxicityによる膵β細胞からのMCP-1分泌の増加と細胞内情報伝達系の関与2008

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 膵β細胞からのMCP-1分泌に及ぼす高濃度グルコースおよび脂肪酸の影響について2007

Author(s)

Organizer

Place of Presentation

Data Source

YOSHIMOTO Katsuhiko 吉元勝彦

吉元勝彦ヨシモトカツヒコ