Re Myeong 李明鎭

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LEE Myeongjin 李明鎭

李明鎮リミヨンジン

李明鎭リミヨンジン

LEE Myeong Jin 李明鎮

LEE Miyojin 李明鎮

LIEE Jin 李明鎮

LEE Myeong jin 李明鎮

LEE Myeong jim 李明鎭

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Researcher Number	20273766
Other IDs
Affiliation (Current)	2022: 大手前大学, 健康栄養学部, 教授
Affiliation (based on the past Project Information) *help	2011: 神戸大学, 大学院・医学研究科, 非常勤講師 2009 – 2011: Kobe University, 医学研究科, 非常勤講師 2007: Kobe University, Graduate School of Medicine, Assistant professor 2007: Kobe University, Graduate School of Medicine, Assistant professor 2005 – 2007: Kobe University, Graduate School of Medicine, Assistant professor, 医学系研究科, 講師 … More 2006: Kobe University, Graduate School of Medicine, Assistant professor, 大学院医学系研究科, 講師 2002 – 2004: Kobe University Graduate School of medicine Lecturer, 大学院・医学系研究科, 講師 2002: 神戸大学, 医学系研究科, 講師 2001: 神戸大学, 大学院・医学系研究科, 助手 1996 – 2000: 神戸大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Hygiene / Public health/Health science / Pediatrics / Hygiene / Public health/Health science Except Principal Investigator Hygiene / Pediatrics / Pediatrics / Public health/Health science
Keywords	Principal Investigator 日本人 / 韓国人 / 選択的スプライシング / カドミウム / G71R / Cd / ZNF265 / HOXB8 / BRCA1 / BRCA2 … More / 東アジア / メチレンテトラヒドロ葉酸還元酵素 / 遺伝子変異 / Hardy-Weinberg equilibrium / 神経芽腫 / 予後決定因子 / Rab15 / レチノイン酸 / がん幹細胞 / 自然消退 / Rab / 細胞極性 / 内分泌攪乱物質 / マイクロフィジオメトリーアッセイ法 / MCF-7細胞 / β-エストラジオール / エストロゲン受容体(α型) / 内分泌撹乱物質 / M1WT3細胞 / carbachol / endocrine disruptor / Microphysiometer System / MCF-7 cell / β-estradiol / estrogen receptor α / cadmium / 発がん性化学物質 / ホメオボックス遺伝子 / スプライシング関連因子 / 重金属 / Carcinogenic compound / Alternative splicing / Cadmium / Homeobox gene / Spliceosomal protein / 乳がん / UGT1A1遺伝子 / -3279 T>G / UGT遺伝子 / Japanese / Korean / breast cancer / UGT1A1 gene / -3279T>G / スプライシング関連蛋白 / SMN遺伝子 / HOX遺伝子 / in vitroスプライシング / splicing related protein / SMN gene / HOX gene … More Except Principal Investigator 脊髄性筋萎縮症 / spinal muscular atrophy / ADAMTS-1 / カドミウム / subtractive suppressive hybridization / cadmium / スプライシング / SMN1遺伝子 / SMN2遺伝子 / hnRNP C1 / C2 / ペプチド核酸 / the SMN1 gene / the SMN2 gene / ジストロフィン / リンパ球 / プロモーター / 化学物質 / 紫外線 / クロロホルム / 遺伝子転写産物 / 内因性レトロウイルス関連遺伝子 / トリハロメタン / トロンボスポンジン / げっ歯類C型レトロウイルス / 発癌 / chemicals / ultraviolet ray / chloroform / mRNA / endogenous murine leukemia virus / アルツハイマー病 / アルミニウム / トロンビン / ERAB蛋白 / Alzheimer's disease / aluminum / thrombin / ERAB / 内分泌撹乱物質 / Subtractive suppressive hybridization / イタイイタイ病 / エストロゲン受容体 / 内分泌攪乱物質 / endocline disruptor / itai-itai disease / estrogen receptor / polymorphism / メッセンジャーRNA前躯体 / スプライシング促進配列 / dsx遺伝子 / ミニ遺伝子 / 抗SMN抗体 / メッセンジャーRNA前駆体 / SMN蛋白 / 可変スプライシング / pre-mRNA / splicing / splicing enhancer sequences / the dsx gene / mini-gene / anti-SMN antibody / in vitroスプライシング / in vitro splicing assay / peptide nucleic acid / エクソン特異的スプライシング促進化合物 / バルプロ酸 / ヒストン脱アセチル化酵素阻害剤 / 転写効率 / スプライシング効率 / エクソン7 / 遺伝子変異 / Tudorドメイン / thetic exon-specific splicing activator / valproic acid Less

Role of Rab family small G proteins in determining the prognosis of neuroblastoma patientsPrincipal Investigator
- Principal Investigator
  
  LEE Myeongjin
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
Research on splicing mechanism using a metal which disrupts splicing reactionPrincipal Investigator
- Principal Investigator
  
  LEE Myeong Jin
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kobe University
Development of Therapy for Spinal Muscular Atrophy Based on the Spliring Modulation Technology
- Principal Investigator
  
  NISHIO Hisahide
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
The effect of UGT gene mutation on breast cancer and osteoporosis in Japanese and KoreanPrincipal Investigator
- Principal Investigator
  
  LEE Myeong Jin
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Public health/Health science
- Research Institution
  Kobe University
Research on the effect of carcinogenic chemical compounds on alternative splicingPrincipal Investigator
- Principal Investigator
  
  LEE Myeong Jin
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kobe University
Development of a new treatment with splicing modulators for spinal muscular atrophy
- Principal Investigator
  
  NSIHIO Hisahide
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
Screening system for chemicals attacking pre-mRNA splicing machinery in cells
- Principal Investigator
  
  NISHIO Hisahide
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kobe University Graduate School of medicine
Detection of endocrine disruptor effect using Microphysiometer SystemPrincipal Investigator
- Principal Investigator
  
  LEE Myeong jin
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kobe University
アルツハイマー病アミロイド・ベーター蛋白の毒性発現の抑制機構(メタロチオネイン及びその類似蛋白とアルミニウムの影響)
- Principal Investigator
  
  SUMINO Kimiaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kobe University
Molecular biological studies on environmental chemical pollutants interfering with endocrine systems
- Principal Investigator
  
  NISHIO Hisahide
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Public health/Health science
- Research Institution
  Kobe University
東アジア諸国の成人病関連遺伝子変異に関する研究Principal Investigator
- Principal Investigator
  
  李明鎭
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Public health/Health science
- Research Institution
  Kobe University
リンパ球特異的に発現するL-ジストロフィンの発現制御機構に関する研究
- Principal Investigator
  
  NISHIO Hisahide
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kobe University
Molecular Biological Analysis of Cells and Tissues from Animals Exposed to Chemicals and Ultraviolet Rays
- Principal Investigator
  
  SUMINO Kimiaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kobe University

All 2012 2011 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Epigallocatechin gallate inhibits sphere formation of neuroblastoma BE(2)-C cells2012
- Author(s)
  Nishimura N, Hartomo TB, Pham TVH, Lee MJ, Yamamoto T, Morikawa S, Hasegawa D, Takeda H, Kawasaki K, Kosaka Y, Yamamoto N, Kubokawa I, Mori T, Yanai T, Hayakawa A, Takeshima Y, Iijima K, Matsuo M, Nishio H
- Journal Title
  
  Environ. Health Prev. Med
  
  Volume: 17 Pages: 246-251
- NAID
  10030617244
- Data Source
  KAKENHI-PROJECT-21591361
[Journal Article] Rab15 alternative splicing is altered in spheres of neuroblastoma cells2012
- Author(s)
  Pham TVH, Hartomo TB, Lee MJ, Hasegawa D, Ishida T, Kawasaki K, Kosaka Y, Yamamoto T, Morikawa S, Yamamoto N, Kubokawa I, Mori T, Yanai T, Hayakawa A, Takeshima Y, Iijima K, Matsuo M, Nishio H and Nishimura N
- Journal Title
  
  Oncol. Rep
  
  Volume: 27 Pages: 2045-2049
- Data Source
  KAKENHI-PROJECT-21591361
[Journal Article] Rab15 expression correlates with retinoic acid-induced differentiation of neuroblastoma cells2011
- Author(s)
  Nishimura N, Pham TVH, Hartomo TB, Lee MJ, Hasegawa D, Takeda H, Kawasaki K, Kosaka Y, Yamamoto T, Morikawa S, Yamamoto N, Kubokawa I, Mori T, Yanai T, Hayakawa A, Takeshima Y, Nishio H and Matsuo M
- Journal Title
  
  Oncol. Rep
  
  Volume: 26 Pages: 145-151
- Data Source
  KAKENHI-PROJECT-21591361
[Journal Article] Hypomutability at the Polyadenine Tract in SMN Intron 3 Shows the Invariability of the a-SMN Protein Structure2008
- Author(s)
  Gunadi, Sasongko, TH, Yusoff, S, Lee, MJ, Nishioka, E, Matsuo, M, Nishio, H
- Journal Title
  
  Ann Hum Genet 72(2)
  
  Pages: 288-291
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] SMN2 and NAP gene dosages in Vietnamese patients with spinal muscular atrophy2008
- Author(s)
  Van, Khanh, TV, Teguh, Haryo, Sasongko, Dang, Diem Hong , Nguyen, Thi, Hoan, Vu, Chi, Dung, Myeongn Jin Lee , Gunadi, Indra, Sari, Kusuma, Harahap, Yasuhiro, Takeshima, Masafumi, Matsuo, Hisahide, Nishio
- Journal Title
  
  Pediatr Int (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] Hypomutability at the Polyadenine Tract in SMN Intron 3 Shows the Invariability of the a-SMN Protein Structure.2008
- Author(s)
  Gunadi, Sasongko TH, Yusoff S, Lee MJ, Nishioka E, matsuo M, Nishio H.
- Journal Title
  
  Ann Hum Genet. 72
  
  Pages: 288-291
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] SMN2 and NAIP gene dosages in Vietnamese patients with spinal muscular atrophy.2008
- Author(s)
  Van Khanh TV, Teguh Haryo Sasongko, Dang Diem Hong, Nguyen Thi Hoan, Vu Chi Dung, Myeong Jin Lee, Gunadi, Indra Sari Kusumma Harahap, Yasuhiro Takeshima, Masafumi Matsuo and Hisahide Nishio.
- Journal Title
  
  Pediatrics International (in press)
- NAID
  10025343726
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins.2007
- Author(s)
  Kotani T, Sutomo R, Sasongko TH, Sadewa AH, Gunadi, Minato T, Fujii E, Endo S, Lee MJ, Ayaki H, Harada Y, Matsuo M, Nishio H.
- Journal Title
  
  J Neurol. 80
  
  Pages: 624-630
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins2007
- Author(s)
  Kotani, T, Sutomo, R, Sasongko, TH, Sadewa, AH, Gunadi, Minato, T,Fujii, E, Endo, S, Lee, MJ, Ayaki, H, Harada, Y, Matsuo, M, Nishio, H
- Journal Title
  
  J Neurol 254(5)
  
  Pages: 624-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] A novel mutation at the N-terminal of SMN Tudor domain inhibits its interaction with target proteins.2007
- Author(s)
  Kotani T, Sutomo R, Sasongko TH, Sadewa AH, Gunadi, Minato T, Fujii E, Endo S, Lee MJ, Ayaki H, Harada Y, Matsuo M, Nishio H.
- Journal Title
  
  J Neurol. 254
  
  Pages: 624-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion2006
- Author(s)
  Lee, MJ, Ayaki, H, Goji, J, Kitamura, K, Nishio, H
- Journal Title
  
  Arch Toxicol 80(10)
  
  Pages: 638-43
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion2006
- Author(s)
  Myeong Jin, Lee
- Journal Title
  
  Archives of Toxicology (Epub ahead of print)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590475
[Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion.2006
- Author(s)
  Lee MJ, Ayaki H, Goji J, Kitamura K, Nishio
- Journal Title
  
  Arch Toxicol. 80
  
  Pages: 638-643
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591151
[Journal Article] Cadmium restores in vitro splicing activity inhibited by zinc-depletion.2006
- Author(s)
  Myeong Jin Lee
- Journal Title
  
  Arch Toxicol (Epub ahead of print)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590475
[Journal Article] Cadmium exposure induces expression of the HOXB8 gene in COS-7 cells
- Author(s)
  Kanako, Nakagawa, Myeong, Jin Lee, Naokom Sasaki, Chiyo, Hayashi, Hisahide, Nishio
- Journal Title
  
  Toxicology in Vitro (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590556
[Presentation] A novel mutation at N-terminal of SMN tudor domain inhibits its interaction with target proteins.2006
- Author(s)
  Nishio H, Lee MJ, Kotani T, Sutomo R, interaction with target proteins. Nishio H, Lee MJ, Kotani T, Sutomo R, Sadewa AH, Sasongko TH, Gunadi, Matsuo M.
- Organizer
  The American Society of Human Genetics 56th Annual Meeting,
- Place of Presentation
  New Orleans
- Year and Date
  2006-11-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591151
[Presentation] A novel mutation at N-terminal of SMN tudor domain inhibits its interaction with target proteins2006
- Author(s)
  Nishio, H, Lee, MJ, Kotani, T, Sutomo, R, Sadewa, AH, Sasongko, TH, Gunadi
- Organizer
  The American Society of Human Genetics 56th Annual Meeting
- Place of Presentation
  New Orleans, Louisiana
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591151

1. NISHIO Hisahide (80189258)

# of Collaborated Projects: 13 results

# of Collaborated Products: 15 results
2. AYAKI Hitoshi (80222701)

# of Collaborated Projects: 6 results

# of Collaborated Products: 5 results
3. SUMINO Kimiaki (90030832)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. MATSUO Masafumi (10157266)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TAKESIMA Ysuhiro (40281141)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. NISHIMURA Noriyuki (00322719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 西本啓介 (00362773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Re Myeong 李 明鎭

LEE Myeongjin 李 明鎭

李 明鎮 リ ミヨンジン

李 明鎭 リ ミヨンジン

LEE Myeong Jin 李 明鎮

LEE Miyojin 李 明鎮

LIEE Jin 李 明鎮

LEE Myeong jin 李 明鎮

LEE Myeong jim 李 明鎭

Research Projects

Research Products

Co-Researchers

Role of Rab family small G proteins in determining the prognosis of neuroblastoma patientsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on splicing mechanism using a metal which disrupts splicing reactionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Therapy for Spinal Muscular Atrophy Based on the Spliring Modulation Technology

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of UGT gene mutation on breast cancer and osteoporosis in Japanese and KoreanPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on the effect of carcinogenic chemical compounds on alternative splicingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a new treatment with splicing modulators for spinal muscular atrophy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Screening system for chemicals attacking pre-mRNA splicing machinery in cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Detection of endocrine disruptor effect using Microphysiometer SystemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アルツハイマー病アミロイド・ベーター蛋白の毒性発現の抑制機構(メタロチオネイン及びその類似蛋白とアルミニウムの影響)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular biological studies on environmental chemical pollutants interfering with endocrine systems

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

東アジア諸国の成人病関連遺伝子変異に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

リンパ球特異的に発現するL-ジストロフィンの発現制御機構に関する研究

Principal Investigator

Re Myeong 李明鎭

LEE Myeongjin 李明鎭

李明鎮リミヨンジン

李明鎭リミヨンジン

LEE Myeong Jin 李明鎮

LEE Miyojin 李明鎮

LIEE Jin 李明鎮

LEE Myeong jin 李明鎮

LEE Myeong jim 李明鎭