KATSUSHI Kurosu 黒須克志

Researcher Number	20291106
Affiliation (based on the past Project Information) *help	2013: 千葉大学, 大学院医学研究院, 講師 2011 – 2013: 千葉大学, 医学部附属病院, 講師 2010 – 2011: 千葉大学, 医学部・附属病院, 講師 2007 – 2009: Chiba University, Graduate School, Dept Respirol, Assistant Prof 2006: Chiba University, Graduate School of Medicine・Department of Respirology, Assistant Professor, 大学院医学研究院, 助手 2002 – 2005: 千葉大学, 大学院・医学研究院, 助手 2003: Chiba University, Graduate School of Medicine, Assistant
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine / Respiratory organ internal medicine
Keywords	Principal Investigator 自己抗体 / 間質性肺炎 / SEREX法 / CD4 positive lymphocyte / idiopathic pulmonary fibrosis / SEREX / CD4陽性T細胞 / 特発性肺線維症 / 肺線維症 / autoantibody … More / 急性増悪 / autoantibodies / Vβ chain / 自己抗原 / Vβ鎖 / 細胞内サイトカインアッセイ / ELISPOT解析 … More Except Principal Investigator siRNA / cDNA microarray / Ku70 / caspase-3 / VEGF / COPD / シスプラチン / 細胞周期 / アポトーシス / 肺癌 / Cell cycle / Multi-modality therapy / Radiotherapy / Gene expression / Cisplatin / がん / 放射線 / 抗がん剤 / マイクロアレイ / マルチモダリティー治療 / 放射線治療 / 遺伝子発現 / obesity / leptin / visceral fat accumulation / hypoxemia / sleep apnea syndrome / 内蔵肥満 / 肥満 / レプチン / 内臓肥満 / 低酸素血症 / 睡眠時無呼吸症候群 / lung cancer / gene therapy / chemosensitivity / radiosensitivity / antisense oligonucleotide / DNA repair gene / 遺伝子治療 / 抗癌剤感受性 / 放射線感受性 / アンチセンス / DNA修復遺伝子 / endothelial cell / mouse / apoptosis / smoking / emphysema / 血管内皮細胞 / Caspase-3 / マウス / 喫煙 / 肺気腫 / 細胞株 / 癌幹細胞 / ゲフィチニブ / メトホルミン / 腫瘍学 / 非閉塞性肺疾患 / 呼吸器感染症 / 肺線維症 / 非閉塞性肺疾患癌 Less

特発性肺線維症急性増悪特異的自己抗体を用いた病態制御機構の解明と臨床応用Principal Investigator
- Principal Investigator
  
  黒須克志
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University
A novel therapy for lung cancer targeting cancer stem cells.
- Principal Investigator
  
  TAKIGUCHI Yuichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University
Analysis of individual difference of an epidermal growth factor receptor downstream signal system
- Principal Investigator
  
  SAKAIDA Emiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University
Peptdes and antbodes therapy by acute exacerbaton of idiopathic pumonary fbross-reated autoantgensPrincipal Investigator
- Principal Investigator
  
  KUROSU Katsushi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University
Analysis of autoantibodies associated with patients of idiopathic pulmonary fibrosisPrincipal Investigator
- Principal Investigator
  
  KATSUSHI Kurosu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University
Screening and validation of target molecules involved in mechanism of multi-modality therapy
- Principal Investigator
  
  TAKIGUCHI Yuichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University
Identification of Annexin 1 as a Novel Autoantigen in Acute Exacerbation of Idiopathic Pulmonary FibrosisPrincipal Investigator
- Principal Investigator
  
  KUROSU Katsushi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University
GENETIC PREDISPOSITION, INFLAMMATION, INTERMITTENT HYPOXIA AND CARDIOVASCULAR COMPLICATIONS IN SLEEP APNEA SYNDROME
- Principal Investigator
  
  TATSUMI Koichiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University
SEREX ANALYSIS OF IPF PATIENS : DEMONSTRATION OF SOME AUTOANTIGENS REACTED WITH CD4 POSITIVE T CELLS IN BRONCHOALVEOLAR LAVAGE FLUIDSPrincipal Investigator
- Principal Investigator
  
  KUROSU Katsushi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University
ROLE OF APOPTOSIS IN EMPHYSEMA
- Principal Investigator
  
  KASAHARA Yasunori
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University
Increase in chemo-and radiotherapy and cancer gene therapy by means of suppression of DNA repair genes
- Principal Investigator
  
  TAKIGUCHI Yuichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University

All 2013 2012 2011 2010 2009 2008 2005 2004

All Journal Article Presentation Patent

[Journal Article] Effect of metformin on residual cells after chemotherapy in a human lung adenocarcinoma cell line.2013
- Author(s)
  Kitazono, S., Takiguchi, Y., Ashinuma, H., Saito-Kitazono, M., Kitamura, A., Chiba, T., Sakaida, E., Sekine, I., Tada, Y., Kurosu, K., Sakao, S., Tanabe, N., Iwama, A., Yokosuka, O. and Tatsumi, K.
- Journal Title
  
  Int. J. Oncol.
  
  Volume: 43 Issue: 6 Pages: 1846-1854
- DOI
  10.3892/ijo.2013.2120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-23689039
[Journal Article] Interaction and cross-resistance of cisplatin and pemetrexed in malignant pleural mesothelioma cell lines2012
- Author(s)
  Kitazono-Saitoh M, Takiguchi Y, Sakaida E, Sekine I, Tanabe N, et al
- Journal Title
  
  Oncology Reports
  
  Volume: 28(1) Pages: 33-40
- DOI
  10.3892/or.2012.1799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590850, KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-24591185
[Journal Article] Feasibility of cytological diagnosis of sarcoidosis with endobronchial US-guided transbronchial aspiration2012
- Author(s)
  Kitamura, A., Takiguchi, Y., Kurosu, K., Takigawa, N., Saegusa, F., Hiroshima, K., Nakajima, T., Tanabe, N., Nakatani, Y., Yoshino, I. and Tatsumi, K.
- Journal Title
  
  Sarcoidosis, Vasculitis, And Diffuse Lung Diseases
  
  Volume: 29 Pages: 82-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591136
[Journal Article] Antiproliferative action of metformin in human lung cancer cell lines2012
- Author(s)
  Ashinuma H, Takiguchi Y, Sakaida E, Sekine I, et al
- Journal Title
  
  Oncology Reports
  
  Volume: 28(1) Pages: 8-14
- DOI
  10.3892/or.2012.1763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590850, KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-23689039
[Journal Article] Antiproliferative action of metformin in human lung cancer cell lines2012
- Author(s)
  H Ashinuma, Y Takiguchi, S Kitazono, M Kitazono-Saitoh, A Kitamura, T Chiba, Y Tada, K Kurosu, E Sakaida, I Sekine, N Tanabe, A Iwama, O Yokosuka, K Tatsumi
- Journal Title
  
  Oncology Reports
  
  Volume: in press Issue: 5 Pages: 2118-2126
- DOI
  10.3892/or_xxxxxxxx
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-20K06424
[Journal Article] Feasibility of cytological diagnosis of sarcoidosis with endobronchial US-guided transbronchial aspiration2012
- Author(s)
  Kitamura A, Takiguchi Y, Kurosu K, Tanabe N, Nakatani Y, Yoshino I, et al
- Journal Title
  
  Sarcoidosis, Vasculitis, And Diffuse Lung Diseases: Official Journal Of WASOG / World Association Of Sarcoidosis And Other Granulomatous Disorders
  
  Volume: 29(2) Pages: 82-89
- Data Source
  KAKENHI-PROJECT-22590850
[Journal Article] Characterization of myofibroblasts in chronic thromboembolic pulmonary hypertension2011
- Author(s)
  Maruoka, Sakao, Kantake, Tanabe
- Journal Title
  
  Int J Cardiol
  
  Volume: 159 Issue: 2 Pages: 119-127
- DOI
  10.1016/j.ijcard.2011.02.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590849, KAKENHI-PROJECT-23591136
[Journal Article] Identification of annexin 1 as a novel autoantigen in acute exacerbation of idiopathic pulmonary fibrosis2008
- Author(s)
  Kurosu K, Takiguchi Y, Okada O, Yumoto N, Seiichiro Sakao, Yuji Tada, Yasunori Kasahara, Nobuhiro Tanabe, Koichiro Tatsumi, Michael Weiden, WilliamN Rom, Takayuki Kuriyama
- Journal Title
  
  J. Immunol 181
  
  Pages: 756-767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590882
[Journal Article] Identification of annexin 1 as a novel autoantigen inacute exacerbation of idiopathic pulmonary fibrosis.2008
- Author(s)
  Kurosu K, Takiguchi Y, Okada O, et al.
- Journal Title
  
  J. Immunol. 181
  
  Pages: 756-767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590882
[Journal Article] T.BCL-6 Mutations in Pulmonary Lymphoproliferative Disorders : Demonstration of an Aberrant Immunological Reaction in HIV-Related Lymphoid Interstitial Pneumonia.2004
- Author(s)
  K Kurosu, Weiden MD, Takiguchi Y, Rom WN, N Yumoto, Jaishree J, Nakata K, Y, Kasahara, N Tanabe, K Tatsumi, Mikata A, T Kuriyama
- Journal Title
  
  J.Immunol 172
  
  Pages: 7116-7122
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590798
[Journal Article] BCL-6 Mutations in Pulmonary Lymphoproliferative Disorders2004
- Author(s)
  K.KUROSU, et al.
- Journal Title
  
  J.Immunology 172
  
  Pages: 7116-7122
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590798
[Patent] 特発性肺線維症の検出マーカー及びキット2005
- Inventor(s)
  黒須克志, 栗山喬之
- Industrial Property Rights Holder
  千葉大学
- Industrial Property Number
  2005-078252
- Filing Date
  2005-03-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590780
[Presentation] Anti-proliferative action of metformin on various types of human lung cancer cell lines2012
- Author(s)
  Hironori Ashinuma, Yuichi Takiguchi,Satoru Kitazono, Miyako Kitazono-Saitoh, Atsushi Kitamura, Yuji Tada, Katsushi Kurosu, Emiko Sakaida, Ikuo Sekine, Nobuhiro Tanabe, Koichiro Tatsumi
- Organizer
  American Association for Cancer Research 2012 Annual Meeting
- Place of Presentation
  Chicago, IL. USA
- Data Source
  KAKENHI-PROJECT-22590850
[Presentation] Effects of metformin on a non-small cell lung cancer cell line with an EGFR mutation2012
- Author(s)
  Satoru Kitazono, Yuichi Takiguchi, Hironori Ashinuma, Miyako Kitazono, Atsushi Kitamura, Yuji Tada, Katsushi Kurosu, Emiko Sakaida, Ikuo Sekine, Koichiro Tatsumi
- Organizer
  American Association for Cancer Research 2012Annual Meeting
- Place of Presentation
  Chicago, IL. USA
- Data Source
  KAKENHI-PROJECT-22590850
[Presentation] Genome-wide cDNA microarray screening of genes related to pemetrexed resistance in mesothelioma cell lines2012
- Author(s)
  Sekine I, Kitazono-Saitoh M, Kurimoto R, Sakaida E, Tada Y, Kurosu K, Tatsumi K, Takiguchi Y
- Organizer
  Paper presented at : 5th Asia Pacific Lung Cancer Conference (APLCC)
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-23591136
[Presentation] Interaction andcross-resistance of cisplatin and pemetrexed in malignant pleural mesothelioma cell lines2012
- Author(s)
  Miyako Kitazono, Yuichi Takiguchi, Satoru Kitazono, Hironori Ashinuma, Atsushi Kitamura, Yuji Tada, Katsushi Kurosu, Emiko Sakaida, Ikuo Sekine, Nobuhiro Tanabe, Masatoshi Tagawa, Koichiro Tatsumi
- Organizer
  American Association for Cancer Research 2012 Annual Meeting
- Place of Presentation
  Chicago, IL. USA
- Data Source
  KAKENHI-PROJECT-22590850
[Presentation] 特発性肺線維症急性増悪における抗アネキシン1抗体の関与について2010
- Author(s)
  黒須克志, 滝口裕一, 黒田文伸, 坂尾誠一郎, 多田裕司, 笠原靖紀, 田邊信宏, 巽浩一郎
- Organizer
  日本内科学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2010-04-09
- Data Source
  KAKENHI-PROJECT-21590982
[Presentation] 特発性肺線維症急性増悪特異的抗アネキシン1抗体の検討2009
- Author(s)
  黒須克志, 滝口裕一, 湯本典夫, 岡田修, 黒田文伸, 坂尾誠一郎, 多田裕司, 笠原靖紀, 田邊信宏, 栗山喬之, 巽浩一郎
- Organizer
  日本呼吸器学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-21590982
[Presentation] 特発性肺線維症急性増悪特異的抗アネキシン1抗体の検討2009
- Author(s)
  黒須克志、滝口裕一、湯本典夫、岡田修、坂尾誠一郎、多田裕次、笠原靖紀、田邊信宏、栗山喬之、巽浩一郎
- Organizer
  日本呼吸器学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-19590882
[Presentation] 特発性肺線維症急性増悪における抗アネキシン1抗体の関与について2008
- Author(s)
  黒須克志、滝口裕一、湯本典夫、岡田修、坂尾誠一郎、多田裕次、笠原靖紀、田邊信宏、栗山喬之、巽浩一郎
- Organizer
  日本呼吸器学会総会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2008-06-17
- Data Source
  KAKENHI-PROJECT-19590882
[Presentation] 突発性肺線維症急性増悪における抗アネキシン1抗体の関与について2008
- Author(s)
  黒須克志
- Organizer
  日本呼吸器学会総会
- Place of Presentation
  神戸国際センター
- Data Source
  KAKENHI-PROJECT-19590882

1. TATSUMI Koichiro (10207061)

# of Collaborated Projects: 10 results

# of Collaborated Products: 13 results
2. TAKIGUCHI Yuuichi (30272321)

# of Collaborated Projects: 9 results

# of Collaborated Products: 17 results
3. KURIYAMA Takayuki (20009723)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
4. TANABE Nobuhiro (40292700)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
5. KASAHARA Yasunori (60343092)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TADA Yuji (50344990)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. SAKAIDA Emiko (60422218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. SAKAO Seiichiro (80431740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. SEKI Naohiko (50345013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HIROSHIMA Kenzo (80218833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KATSUSHI Kurosu 黒須 克志

Research Projects

Research Products

Co-Researchers

特発性肺線維症急性増悪特異的自己抗体を用いた病態制御機構の解明と臨床応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A novel therapy for lung cancer targeting cancer stem cells.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of individual difference of an epidermal growth factor receptor downstream signal system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Peptdes and antbodes therapy by acute exacerbaton of idiopathic pumonary fbross-reated autoantgensPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of autoantibodies associated with patients of idiopathic pulmonary fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Screening and validation of target molecules involved in mechanism of multi-modality therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of Annexin 1 as a Novel Autoantigen in Acute Exacerbation of Idiopathic Pulmonary FibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

GENETIC PREDISPOSITION, INFLAMMATION, INTERMITTENT HYPOXIA AND CARDIOVASCULAR COMPLICATIONS IN SLEEP APNEA SYNDROME

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

SEREX ANALYSIS OF IPF PATIENS : DEMONSTRATION OF SOME AUTOANTIGENS REACTED WITH CD4 POSITIVE T CELLS IN BRONCHOALVEOLAR LAVAGE FLUIDSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ROLE OF APOPTOSIS IN EMPHYSEMA

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Increase in chemo-and radiotherapy and cancer gene therapy by means of suppression of DNA repair genes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effect of metformin on residual cells after chemotherapy in a human lung adenocarcinoma cell line.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interaction and cross-resistance of cisplatin and pemetrexed in malignant pleural mesothelioma cell lines2012

Author(s)

Journal Title

DOI

Data Source

KATSUSHI Kurosu 黒須克志