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Shimura Masahiko  志村 雅彦

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SHIMURA Masahiko  志村 雅彦

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Researcher Number 20302135
Affiliation (Current) 2025: 東京医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2021 – 2023: 東京医科大学, 医学部, 教授
2013 – 2018: 東京医科大学, 医学部, 教授
2002 – 2003: Tohoku University Hospital, Lecturer, 医学部附属病院, 講師
2002: 東北大学, 医学部附属病院, 助手
2001: 東北大学, 医学部・附属病院, 助手
Review Section/Research Field
Principal Investigator
Ophthalmology / Basic Section 56060:Ophthalmology-related / Ophthalmology
Except Principal Investigator
Ophthalmology / Basic Section 56060:Ophthalmology-related
Keywords
Principal Investigator
糖尿病黄斑浮腫 / 治療プロトコール / サイトカイン / パッチクランプ法 / 内向き整流性カリウムチャネル / 毛様体無色素上皮細胞 / 網膜色素上皮細胞 / 予後 / 治療 / 疫学調査 … More / 生理活性 / 眼科学 / 臨床 / 投与プロトコール / 感受性 / VEGF阻害薬 / Iris pigment epithelium / permeability / Ion channel / Patch clamp recordings / inward rectifier potassium (Kir) channel / Retinal pigment epithelium / 浮遊細胞 / 硝子体手術 / Kir7.1チャネル / 虹彩色素上皮細胞 / イオン透過性 / イオンチャネル / 眼循環圧 / 加齢変化 / 黄斑浮腫 / 糖尿病 / 糖尿病網膜症 / 網膜血流 / 前房水 / 網膜硝子体疾患 / 血流 / クロライドチャネル … More
Except Principal Investigator
黄斑浮腫 / 生物活性因子 / イメージ画像 / 網膜循環障害 / サイトカイン / 重症糖尿病 / 前房フレア / 糖尿病 / 白内障手術 / 硝子体手術 / レーザーフレアセル / 術後炎症 / 糖尿病網膜症 Less
  • Research Projects

    (8 results)
  • Research Products

    (30 results)
  • Co-Researchers

    (6 People)
  •  網膜循環障害に伴う黄斑浮腫のイメージ画像・眼内生物活性因子の網羅的解析

    • Principal Investigator
      野間 英孝
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Tokyo Medical University
  •  Survey on the treatment of diabetic macular edema and prognostic results in JapanPrincipal Investigator

    • Principal Investigator
      Shimura Masahiko
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Tokyo Medical University
  •  網膜静脈閉塞の眼内生物活性因子・経時的解析によるオーダーメード治療の展開

    • Principal Investigator
      野間 英孝
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Tokyo Medical University
  •  Treatment strategy for diabetic macular edema based on clinical and basic researchPrincipal Investigator

    • Principal Investigator
      Shimura Masahiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Tokyo Medical University
  •  Postoperative inflammation of ocular surgery in patients with diabetetes mellitus

    • Principal Investigator
      Yasuda Kanako
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Tokyo Medical University
  •  Individualization of treatment therapy for diabetic macular edema by laser speckle flowgraphyPrincipal Investigator

    • Principal Investigator
      Shimura Masahiko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Tokyo Medical University
  •  網膜色素上皮細胞による網膜下腔イオン環境制御機構の解明Principal Investigator

    • Principal Investigator
      志村 雅彦
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Functional Properties and Regulation of Retinal Pigment EpithelialPrincipal Investigator

    • Principal Investigator
      SHIMURA Masahiko
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University

All 2023 2018 2017 2016 2014 Other

All Journal Article Presentation Other

  • [Journal Article] Clinical preferences and trends of anti-vascular endothelial growth factor treatments for diabetic macular edema in Japan2018

    • Author(s)
      Sugimoto Masahiko、Tsukitome Hideyuki、Okamoto Fumiki、Oshika Tetsuro、Ueda Tetsuo、Niki Masanori、Mitamura Yoshinori、Ishikawa Hiroto、Gomi Fumi、Kitano Shigehiko、Noma Hidetaka、Shimura Masahiko、Sonoda Shozo、Sawada Osamu、Ohji Masahito、Harimoto Kozo、Takeuchi Masaru、Takamura Yoshihiro、Kondo Mineo、Sakamoto Taiji
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 10 Issue: 2 Pages: 475-483

    • DOI

      10.1111/jdi.12929

    • NAID

      120006980552

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09418, KAKENHI-PROJECT-17K19721, KAKENHI-PROJECT-18H02954, KAKENHI-PROJECT-16K11272, KAKENHI-PROJECT-16K11337
  • [Journal Article] Phase II/III Clinical Trial of Sub-Tenon Injection of Triamcinolone Acetonide (WP-0508ST) for Diabetic Macular Edema2018

    • Author(s)
      Ogura Yuichiro、Shimura Masahiko、Iida Tomohiro、Sakamoto Taiji、Yoshimura Nagahisa、Yamada Mie、Ishibashi Tatsuro
    • Journal Title

      Ophthalmologica

      Volume: 241 Issue: 3 Pages: 161-169

    • DOI

      10.1159/000492135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K11272
  • [Journal Article] Aqueous cytokine and growth factor levels indicate response to ranibizumab for diabetic macular oedema2017

    • Author(s)
      Shimura M, Yasuda K, Motohashi R, Kotake O, Noma H
    • Journal Title

      British Journal of Ophthalmology

      Volume: - Issue: 11 Pages: 1518-1523

    • DOI

      10.1136/bjophthalmol-2016-309953

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K11272
  • [Journal Article] Reduction of the frequency of intravitreal bevacizumab by posterior subtenon injection of triamcinolone acetonide in patients with diffuse diabetic macular edema2016

    • Author(s)
      Shimura M, Yasuda K, Minezaki T, Noma H
    • Journal Title

      Jpn J Ophthalmol

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462737
  • [Journal Article] Comparative effects of topical diclofenac and metamethasone on inflammation after vitrectomy and cataract surgery in various vitreoretinal disease2016

    • Author(s)
      32.Yasuda, K., Motohashi, R., Kotake, O., Nakagawa, H., Noma, H. and Shimura, M.
    • Journal Title

      Journal of Ocular Pharmacology and Therapeutics

      Volume: 32 Pages: 677-684

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K10849
  • [Journal Article] Pulse waveform analysis of normal population using laser speckle flowgraphy.2014

    • Author(s)
      Tsuda, S., Kunikata, H., Shimura, M., Kunikata, H., Aizawa, N., Omodaka, K., Shiga, Y., Yasuda, M., Yokoyama, Y. and Nakazawa, T.
    • Journal Title

      Curr Eye Res

      Volume: 39 Issue: 12 Pages: 1207-1215

    • DOI

      10.3109/02713683.2014.905608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462737
  • [Journal Article] Relative flow volume, a novel blood flow index in the human retina derived from laser speckle flowgraphy2014

    • Author(s)
      Shiga T, Shimura M, ......., Nakazawa T
    • Journal Title

      Investigative Ophthalmology & Visual Sciences

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462737
  • [Journal Article] Relationship of skin autofluorescence to severity of retiniopathy in type 2 diabetes2014

    • Author(s)
      Yasuda M, Shimura M, ....Yasuda K,......Nakazawa T.
    • Journal Title

      Current Eye Research

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462737
  • [Presentation] Real-world management of treatment-naive diabetic macular edema after the approval of anti-VEGF therapy in Japan: 2-year visual outcome focusing on the starting year of intervention from STREAT-DME 2 study2023

    • Author(s)
      Shimura M, Kitano S, Sakamoto T on behalf of J-CREST study Group
    • Organizer
      Annual Meeting of ARVO 2023 in New Orleans
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09685
  • [Presentation] Real-world management of treatment-naive diabetic macular edema after the approval of anti-VEGF therapy in Japan: 2-year visual outcome focusing on the starting year of intervention from STREAT-DME 2 study2023

    • Author(s)
      Shimura M, Kitano S, Sakamoto T on behalf of STREAT-DME 2 study group
    • Organizer
      ARVO2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09685
  • [Presentation] わが国における糖尿病黄斑浮腫に対する2年間の治療成績の年度別推移2023

    • Author(s)
      志村雅彦、朝蔭正樹、柳田紘生、安田佳奈子、野間英孝
    • Organizer
      日本糖尿病眼学会総会
    • Data Source
      KAKENHI-PROJECT-21K09685
  • [Presentation] 網膜静脈分枝閉塞症に伴う黄斑浮腫における抗VEGF薬治療後の網膜感度の検討2023

    • Author(s)
      野中椋太, 野間英孝, 安田佳奈子, 佐々木翔太郎, 鳥生知加, 後藤 浩, 志村雅彦
    • Organizer
      第62回日本網膜硝子体学会総会
    • Data Source
      KAKENHI-PROJECT-22K09821
  • [Presentation] 無縫合硝子体手術後の術後眼圧変動についての検討2018

    • Author(s)
      内海卓也、安田佳奈子、志村雅彦
    • Organizer
      2018年日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-15K10849
  • [Presentation] 抗VEGF薬治療に抵抗する糖尿病黄斑浮腫におけるサイトカイン濃度変化2018

    • Author(s)
      野間英孝、安田佳奈子、志村雅彦
    • Organizer
      日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-16K11272
  • [Presentation] 糖尿病黄斑浮腫の病態と治療2017

    • Author(s)
      志村雅彦
    • Organizer
      第72回日本眼科医会生涯教育講座
    • Place of Presentation
      東京都
    • Year and Date
      2017-02-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K11272
  • [Presentation] Role of Soluble Vascular Endothelial Growth Factor Receptor Signaling and Other2016

    • Author(s)
      Noma H, Yasuda K, Shimura M
    • Organizer
      2016 Annual Meeting of Association for Research in Vision and Ophthalmology
    • Place of Presentation
      Seatle
    • Year and Date
      2016-05-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10849
  • [Presentation] Vitreous concentrations of cytokines indicates visual prognosis after vitrectomy in patients with rhegmatogenous retinal detachment2016

    • Author(s)
      Shimura M, Motohashi R, Yasuda K, Noma H
    • Organizer
      2016 Annual Metting of Association for Research in Vision and Ophthalmology
    • Place of Presentation
      Seatle USA
    • Year and Date
      2016-05-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462737
  • [Presentation] Dynamic change of aqueous concentrations of VEGF and its soluble receptors during the treatment of aflibercept in patients with age-related macular degeneration2014

    • Author(s)
      Tanaka A, ...., Yasuda K, Noma H, Shimura M
    • Organizer
      Asscosiation for Research and Vision in Ophthalmology 2014
    • Place of Presentation
      Orland FL, USA
    • Data Source
      KAKENHI-PROJECT-25462737
  • [Presentation] Changes of Arterial and Venous Blood Flow Velocities at Retinal Bifurcations2014

    • Author(s)
      Shimura M, ......, Yasuda K, Noma H.
    • Organizer
      Asscosiation for Research and Vision in Ophthalmology 2014
    • Place of Presentation
      Orland FL, USA.
    • Data Source
      KAKENHI-PROJECT-25462737
  • [Presentation] 硝子体手術の功罪「黄斑浮腫」2014

    • Author(s)
      志村雅彦
    • Organizer
      第118回日本眼科学会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-25462737
  • [Presentation] Efficacy and Safety of Intravitreal Aflibercept for Diabetic Macular Edema:VIVIDDME

    • Author(s)
      Masahiko Shimura
    • Organizer
      Asia Pacific Macula Meeting 2014
    • Place of Presentation
      Singapore
    • Year and Date
      2014-10-10 – 2014-10-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-25462737
  • [Presentation] Dynamic change of aqueous concentrations of cytokines and their receptors during the clinical course of ranibizumab treatment in diabetic macular edema.

    • Author(s)
      Masahiko Shimura
    • Organizer
      Associartion for Research in Vision and Ophthalmology
    • Place of Presentation
      Denver
    • Year and Date
      2015-05-02 – 2015-05-07
    • Data Source
      KAKENHI-PROJECT-25462737
  • [Presentation] Urrent opinion on optimal anti-VEGF for wAMD treatment

    • Author(s)
      Masahiko Shimura
    • Organizer
      2014 Annual Meeting of Taiwan Ophthalmological Scoiety
    • Place of Presentation
      Taipei
    • Year and Date
      2014-12-13 – 2014-12-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-25462737
  • [Presentation] Comaparative evaluation of dynamic change of aqueous concentration of VEGF receptorsa between ranibizumab and aflibercept in patients with wet AMD

    • Author(s)
      Masahiko Shimura
    • Organizer
      American Academy of Ophthalmology 2014
    • Place of Presentation
      Chicago
    • Year and Date
      2014-10-16 – 2014-10-22
    • Data Source
      KAKENHI-PROJECT-25462737
  • [Presentation] Current Treatment Approaches and Unmet medical needs in PCV among Asians

    • Author(s)
      Masahiko Shimura
    • Organizer
      Asia Pacific Macula Meeting 2014
    • Place of Presentation
      Singapore
    • Year and Date
      2014-10-10 – 2014-10-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-25462737
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  • 1.  YASUDA Kanako (70647461)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 13 results
  • 2.  野間 英孝 (80304442)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 3.  YAMAGUCHI Katsuhiro (20200610)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  TOMITA Hiroshi (40302088)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  中澤 徹 (30361075)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  上田 哲生
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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