TOMITA Takeshi 富田毅

Researcher Number	20302242
Other IDs	https://orcid.org/0000-0001-6815-2244
External Links
Affiliation (Current)	2024: 信州大学, 学術研究院医学系, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 信州大学, 学術研究院医学系, 准教授 2009 – 2017: Tokyo Women's Medical University, 医学部, 助教 2003: 東北大, 多元物質科学研究所, 助手 2001 – 2003: Institute for Multidisciplinaiy Research for Advanced Materials, Research Associate, 多元物質科学研究所, 助手 2000: 東北大学, 反応化学研究所, 助手
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Functional biochemistry / General medical chemistry / Pathological medical chemistry / Functional biochemistry Except Principal Investigator Basic Section 50010:Tumor biology-related / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Functional biochemistry / Structural biochemistry / Biological Sciences / Biological Sciences
Keywords	Principal Investigator 細胞外RNA / 血清アミロイド / 血清アミロイドA3 / 抗転移細胞 / プルダウンアッセイ / タンパク質核酸相互作用 / タンパク質間相互作用 / SAA3 / ZFC3H1 / mTOC … More / 亜鉛フィンガータンパク質 / MTR4 / C1D / 炎症性サイトカイン / セラストラマイシン / S100A8 / TLR4 / 酸化LDL受容体 / クララ細胞 / 腫瘍転移 / 分子腫瘍学 / PASドメイン / 酸素センサー / 共鳴ラマン分光 / センサーヘムタンパク質 … More Except Principal Investigator ヘム / X線結晶構造解析 / ヘムオキシゲナーゼ / 細胞外RNA / 転移前ソイル / 抗転移細胞 / heme oxygenase / がん転移 / 共鳴ラマン / 反応中間体 / がん転移抑制 / RNA結合タンパク質 / 癌転移 / RNA結合受容体 / メッセンジャ-RNA / 組織特異的 / 転移前土壌 / 抗転移 / 疲弊回復 / NK細胞 / がんの転移 / oxygen activation / Reaction mechanism / X-ray crystallography / Heme / 酸素活性化 / intermediate of enzyme reaction / resonance Raman spectra / X-ray crystal structure / heme / 一酸化炭素 / 共鳴ラマンスペクトル / 結晶化 / 酵素反応中間体 / 増殖因子 / ケモカイン / 癌 / がん / 転移 / TLR / 内因性リガンド / 炎症 / ADAM12 / CCR2 / 自然免疫 / ephrinA1 / CCL2 / S100A8 / SAA3 / TLR4 / 構造生物学 / センサーヘムタンパク質 / 可溶性グアニル酸シクラーゼ / ヘム分解 / 反応解析 / 阻害剤 Less

細胞外RNA受容体ZC3H12Dの細胞内機能解析Principal Investigator
- Principal Investigator
  
  富田毅
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Shinshu University
哺乳類における細胞表面RNA結合タンパク質の解明
- Principal Investigator
  
  中村佐千枝 (平塚佐千枝)
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Shinshu University
細胞外RNAによる抗転移細胞活性化の解明
- Principal Investigator
  
  中村佐千枝 (平塚佐千枝)
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Shinshu University
抗転移細胞で特異的に発現するタンパク質の分子機序解明Principal Investigator
- Principal Investigator
  
  富田毅
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Shinshu University
Anti-metastatic cells in tumor-stimulated organs
- Principal Investigator
  
  Hiratsuka Sachie
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Shinshu University
Biochemical characterization of an inflammation related protein, mTOC (Celastramycin binding protein)Principal Investigator
- Principal Investigator
  
  Tomita Takeshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Shinshu University
  Tokyo Women's Medical University
Serum amyloid A3 and intracellular signaling protein mTOCPrincipal Investigator
- Principal Investigator
  
  Tomita Takeshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Women's Medical University
Roles of oxidized LDL receptor and TLR4 signaling in lung metastasisPrincipal Investigator
- Principal Investigator
  
  TOMITA Takeshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Women's Medical University
Endogenous TLR4 ligands in tumor metastasis.
- Principal Investigator
  
  MARU Yoshiro
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Women's Medical University
Molecular mechanism of serum amyloid signaling in lung metastasisPrincipal Investigator
- Principal Investigator
  
  TOMITA Takeshi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Women's Medical University
二原子分子受容体の作用メカニズムPrincipal Investigator
- Principal Investigator
  
  富田毅
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tohoku University
Following Heme Oxygenase Reaction at Atomic Scale
- Principal Investigator
  
  SAITO Masao
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tohoku University
NO-cGMP系情報伝達システムの分子機構
- Principal Investigator
  
  IKEDA-SAITO Masao
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Structure and Function of heme related proteins involved in intracellular signal transduction
- Principal Investigator
  
  IKEDA-SAITO Masao
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  TOHOKU UNIVERSITY

All 2023 2021 2018 2016 2015 2014 2013 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] 細胞工学2014
- Author(s)
  富田毅、丸義朗
- Publisher
  株式会社　学研メディカル秀潤社
- Data Source
  KAKENHI-PLANNED-21117008
[Journal Article] Suppression of CEBPδ recovers exhaustion in anti-metastatic immune cell2023
- Author(s)
  Chenxue Yin, Masayoshi Kato, Takeshi Tomita, Yibing Han, Sachie Hiratsuka
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 3903-3903
- DOI
  10.1038/s41598-023-30476-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24161
[Journal Article] Extracellular mRNA transported to the nucleus exerts translation-independent function2021
- Author(s)
  Tomita Takeshi、Kato Masayoshi、Mishima Taishi、Matsunaga Yuta、Sanjo Hideki、Ito Ken-ichi、Minagawa Kentaro、Matsui Toshimitsu、Oikawa Hiroyuki、Takahashi Satoshi、Takao Toshifumi、Iwai Noriki、Mino Takashi、Takeuchi Osamu、Maru Yoshiro、Hiratsuka Sachie
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 3655-3655
- DOI
  10.1038/s41467-021-23969-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06577, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-19H03488, KAKENHI-PROJECT-19H03500, KAKENHI-PROJECT-20K06554, KAKENHI-PROJECT-21K06868, KAKENHI-PROJECT-19H03506, KAKENHI-PROJECT-21H02438
[Journal Article] C1D is not directly involved in the repair of UV-damaged DNA but protects cells from oxidative stress by regulating gene expressions in human cell lines.2018
- Author(s)
  Tomita T, Ieguchi K, Takita M, Tsukahara F, Yamada M, Egly JM, Maru Y.
- Journal Title
  
  J Biochem
  
  Volume: 164 Pages: 415-426
- DOI
  10.1093/jb/mvy069
- NAID
  40021789520
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07346, KAKENHI-PROJECT-16K07252
[Journal Article] 肺がんへの転移とS100A82016
- Author(s)
  富田　毅、丸　義朗
- Journal Title
  
  生体の科学
  
  Volume: 67 Pages: 460-461
- Data Source
  KAKENHI-PROJECT-26440063
[Journal Article] Eritoran inhibits S100A8-mediated TLR4/MD-2 activation and tumor growth by changing the immune microenvironment.2016
- Author(s)
  Deguchi A, Tomita T, Ohto U, Takemura K, Kitao A, Akashi-Takamura, S, Miyake K, and Maru Y.
- Journal Title
  
  Oncogene
  
  Volume: 35 Issue: 11 Pages: 1445-1456
- DOI
  10.1038/onc.2015.211
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06842, KAKENHI-PROJECT-26440063, KAKENHI-PROJECT-15K14471, KAKENHI-PLANNED-25104002, KAKENHI-PROJECT-15H04357, KAKENHI-PROJECT-26711002, KAKENHI-PROJECT-15K09491
[Journal Article] Drug Targeting Based on a New Concept-Targeting Against TLR4 as an Example.2015
- Author(s)
  Maru Y, Tomita T, Deguchi A, Ieguchi K, Takita M, Tsukahara F, Takemura K, Kitao A, Gusovsky F.
- Journal Title
  
  Endocr Metab Immune Disord Drug Targets.
  
  Volume: 15 Pages: 83-87
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440063
[Journal Article] Human serum amyloid A3 (SAA3) protein, expressed as a fusion protein with SAA2, binds the oxidized low density lipoprotein receptor.2015
- Author(s)
  Tomita T, Ieguchi K, Sawamura T, Maru Y
- Journal Title
  
  PLoS One
  
  Volume: 10(3) Issue: 3 Pages: e0118835-e0118835
- DOI
  10.1371/journal.pone.0118835
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25122716, KAKENHI-PROJECT-25293063, KAKENHI-PROJECT-25870760, KAKENHI-PROJECT-26440063
[Journal Article] TLR4/MD-2の蛋白質内因性リガンドと癌転移の分子基盤2015
- Author(s)
  富田　毅、丸　義朗
- Journal Title
  
  医学のあゆみ
  
  Volume: 253 Pages: 1099-1103
- Data Source
  KAKENHI-PROJECT-26440063
[Journal Article] ADAM12-cleaved ephrin-A1 contributes to lung metastasis2014
- Author(s)
  Ieguchi K, Tomita T, Omori T, Komatsu A, Deguchi A, Masuda J, Duffy S, Coulthard M, Boyd A, Maru Y
- Journal Title
  
  Oncogene
  
  Volume: 33(17) Pages: 2179-2190
- Data Source
  KAKENHI-PLANNED-21117008
[Journal Article] ADAM12-cleaved ephrin-A1 contributes to lung metastasis.2014
- Author(s)
  Ieguchi K, Tomita T, Omori T, Komatsu A, Deguchi A, Masuda J, Duffy SL, Coulthard MG, Boyd A, Maru Y.
- Journal Title
  
  Oncogene
  
  Volume: 未定 Issue: 17 Pages: 2179-90
- DOI
  10.1038/onc.2013.180
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590347, KAKENHI-PROJECT-24501321, KAKENHI-PUBLICLY-25122716, KAKENHI-PROJECT-25860797, KAKENHI-PROJECT-25870760, KAKENHI-PROJECT-26640079
[Journal Article] ZFC3H1, a Zinc Finger Protein, Modulates IL-8 Transcription by Binding with Celastramycin A, a Potential Immune Suppressor2014
- Author(s)
  Tomita T, Ieguchi K, Coin F, Kato Y, Kikuchi H, Oshima Y, Kurata S, Maru Y
- Journal Title
  
  PLoS One
  
  Volume: 30 Issue: 9 Pages: e108957-e108957
- DOI
  10.1371/journal.pone.0108957
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390014, KAKENHI-PUBLICLY-25122716, KAKENHI-PROJECT-25870760, KAKENHI-PROJECT-26440063
[Journal Article] 臓器連関とがん転移前土壌形成2014
- Author(s)
  富田　毅、丸　義朗
- Journal Title
  
  細胞工学
  
  Volume: 33 Pages: 508-511
- Data Source
  KAKENHI-PROJECT-26440063
[Journal Article] ADAM12-cleaved ephrin-A1 contributes to lung metastasis2014
- Author(s)
  Ieguchi K., TOMITA T., Omori T., Komatsu A., Deguchi A., Masuda J., Duffy S., Coulthard M., Boyd A., Maru Y.
- Journal Title
  
  Oncogene
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-23590347
[Journal Article] Ephrin-A1 expression induced by S100A8 is mediated by the toll-like receptor 42013
- Author(s)
  Ieguchi K, Omori T, Komatsu A, Tomita T, Deguchi A, Maru Y
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 440(4) Pages: 623-629
- Data Source
  KAKENHI-PLANNED-21117008
[Journal Article] Ephrin-A1 expression induced by S100A8 is mediated by the toll-like receptor 42013
- Author(s)
  Ieguchi K., Omori T., Komatsu A., TOMITA T., Deguchi A., Maru Y.
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 440 Pages: 623-629
- Data Source
  KAKENHI-PROJECT-23590347
[Journal Article] Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci2013
- Author(s)
  Hiratsuka S, Ishibashi S, Tomita T, Watanabe A, Tamura SA, Murakami M, Kijima H, Miyake K, Aburatani H, Maru Y
- Journal Title
  
  Nat Commun
  
  Volume: 4 Issue: 1 Pages: 1853-1853
- DOI
  10.1038/ncomms2856
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21117008, KAKENHI-PROJECT-23590386, KAKENHI-PROJECT-23590564, KAKENHI-PROJECT-24221011
[Journal Article] Serum Amyroid A3 binds MD-2 to activates p38 and NF-kB pathway in a MyD88-dependent manner2013
- Author(s)
  Deguchi A, Tomita T, Omori T, Komatsu A, Ohto U, Takahashi S, Tanimura N, Akashi-Takamura S, Miyake K, Maru Y
- Journal Title
  
  J Immunol. 2013
  
  Volume: 191, 4, 2013 Pages: 1856-1864
- Data Source
  KAKENHI-PLANNED-21117008
[Journal Article] Serum amyloid A3 binds MD-2 to activate p38 and NF-κB pathways in a MyD88-dependent manner2013
- Author(s)
  Deguchi A., TOMITA T., Omori T., Komatsu A., Ohto U., Takahashi S., Tanimura N., Akashi-Takamura S., Miyake K., Maru Y.
- Journal Title
  
  J. Immunol
  
  Volume: 191 Pages: 1856-1864
- Data Source
  KAKENHI-PROJECT-23590347
[Journal Article] Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci2013
- Author(s)
  Hiratsuka S, Ishibashi S, Tomita T, Watanabe A, Tamura S, Murakami M, Kijima H, Miyake K, Aburatani H, Maru Y
- Journal Title
  
  Nat Commun
  
  Volume: 4 Pages: 1853-1853
- Data Source
  KAKENHI-PLANNED-21117008
[Journal Article] Ephrin-A1 expression induced by S100A8 is mediated by the toll-like receptor 42013
- Author(s)
  Ieguchi K, Omori T, Komatsu A, Tomita T, Deguchi A, Maru Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 440(4) Issue: 4 Pages: 623-629
- DOI
  10.1016/j.bbrc.2013.09.119
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21117008, KAKENHI-PROJECT-23590347, KAKENHI-PROJECT-24501321, KAKENHI-PUBLICLY-25122716, KAKENHI-PROJECT-25870760
[Journal Article] Serum Amyroid A3 binds MD-2 to activates p38 and NF-kB pathway in a MyD88-dependent manner2013
- Author(s)
  Deguchi A, Tomita T, Omori T, Komatsu A, Ohto U, Takahashi S, Tanimura N, Akashi-Takamura S, Miyake K, Maru Y
- Journal Title
  
  J Immunol
  
  Volume: 191(4) Issue: 4 Pages: 1856-1864
- DOI
  10.4049/jimmunol.1201996
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21117008, KAKENHI-PROJECT-23590347, KAKENHI-PROJECT-23590564, KAKENHI-PROJECT-24501321, KAKENHI-PUBLICLY-25115504, KAKENHI-PUBLICLY-25121709, KAKENHI-PROJECT-25650029
[Journal Article] Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci2013
- Author(s)
  Hiratsuka S., Ishibashi S., TOMITA T., Watanabe A., Akashi-Takamura S., Murakami M., Kijima H., Miyake K., Aburatani H., Maru Y.
- Journal Title
  
  Nat. Commun
  
  Volume: 4 Pages: 1853-1853
- Data Source
  KAKENHI-PROJECT-23590347
[Journal Article] Imbalance of Clara cell-mediated homeostatic inflammation is involved in lung metastasis2011
- Author(s)
  Tomita T., Sakurai Y., Ishibashi S., Maru Y.
- Journal Title
  
  Oncogene
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790330
[Journal Article] FOXA1 plays a role in regulating Secretoglobin 1a1 expression in the absence of CAATT/Enhancer Binding Protein activities in lung in vivo2011
- Author(s)
  Kido T., Tomita T., Okamoto M., Cai Y., Matsumoto Y., Vinson C., Maru Y., Kimura S.
- Journal Title
  
  Am.J.Physiol Lung Cell Mol.Physiol.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790330
[Journal Article] FOXA1 plays a role in regulating secretoglobin 1a1 expression in the absence of CCAAT/enhancer binding protein activities in lung in vivo2011
- Author(s)
  Kido T, Tomita T, Okamoto M, Cai Y, Matsumoto Y, Vinson C, Maru Y, Kimura S
- Journal Title
  
  American Journal of Physiology-Lung Cellular and Molecular Physiology
  
  Volume: 300 Issue: 3 Pages: L441-L452
- DOI
  10.1152/ajplung.00435.2009
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21117008
[Journal Article] Imbalance of Clara cell-mediated homeostatic inflammation is involved in lung metastasis2011
- Author(s)
  Tomita T, Sakurai Y, Ishibashi S, Maru Y
- Journal Title
  
  Oncogene
  
  Volume: 30 Issue: 31 Pages: 3429-3439
- DOI
  10.1038/onc.2011.53
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21117008
[Journal Article] Imbalance of Clara cell-mediated homeostatic inflammation is involved in lung metastasis2011
- Author(s)
  Tomita T, Sakurai Y, Ishibashi S, Maru Y
- Journal Title
  
  Oncogene.
  
  Volume: 30 Pages: 3429-3439
- Data Source
  KAKENHI-PLANNED-21117008
[Journal Article] Imbalance of Clara cell-mediated homeostatic inflammation is involved in lung metastasis.2011
- Author(s)
  Tomita T, Sakurai Y, Ishibashi S, Maru Y.
- Journal Title
  
  Oncogene
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21117008
[Journal Article] FOXA1 plays a role in regulating Secretoglobin 1a1 expression in the absence of CAATT/Enhancer Binding Protein activities in lung in vivo2011
- Author(s)
  Kido T., Tomita T., Okamoto M., Cai Y., Matsumoto Y., Vinson C., Maru Y., Kimura S.
- Journal Title
  
  Am.J.Physiol.Lung Cell Mol.Physiol. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790330
[Journal Article] Imbalance of Clara cell-mediated homeostatic inflammation is involved in lung metastasis2011
- Author(s)
  Tomita T., Sakurai Y., Ishibashi S., Maru Y.
- Journal Title
  
  Oncogene in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790330
[Presentation] 転移前土壌の消失をめざして2021
- Author(s)
  平塚佐千枝、富田　毅
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K06554
[Presentation] Characterization of Celastramycin Binding Protein2015
- Author(s)
  TOMITA T.
- Organizer
  The 3rd Homeostatic Inflammation International Symposium
- Place of Presentation
  東京大学医科学研究所
- Year and Date
  2015-01-29
- Data Source
  KAKENHI-PROJECT-26440063
[Presentation] 肺転移におけるephrin-A1とADAM12の機能解析2013
- Author(s)
  家口勝昭、富田　毅、丸義朗
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590347
[Presentation] 肺転移におけるephrin-A1とADAM12の機能解析2013
- Author(s)
  家口勝昭, 富田毅, 丸義朗
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590347
[Presentation] 肺転移での転移前土壌形成における自然免疫の役割2013
- Author(s)
  富田　毅、平塚佐千枝、丸義朗
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590347
[Presentation] ADAM12-cleaved ephrin-A1 contributes to lung metastasis.2013
- Author(s)
  Ieguchi Katsuaki, Tomita Takeshi, Yoshiro Maru
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜、日本
- Data Source
  KAKENHI-PLANNED-21117008
[Presentation] 肺転移での転移前土壌形成における自然免疫の役割2013
- Author(s)
  富田毅, 平塚佐千枝, 丸義朗
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590347
[Presentation] Imbalance of Clara-cell mediated homeostatic inflammation is involved in lung metastasis2011
- Author(s)
  Tomita T
- Organizer
  第13回TNF国際会議
- Place of Presentation
  淡路市
- Data Source
  KAKENHI-PROJECT-23590347
[Presentation] 肺上皮細胞による自然炎症と転移2011
- Author(s)
  富田　毅、丸　義朗
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590347
[Presentation] lung metastasis and homeostatic inflammation mediated by lung epithelial cells2011
- Author(s)
  富田毅, 丸義朗
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590347
[Presentation] Clara cell regulates organotropism in pulmonary metastasis via S100A8-serum amyloid A3-TLR4 signaling2010
- Author(s)
  Tomita T., Maru Y.
- Organizer
  69^<th> Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21790330
[Presentation] Organ specific resident cells with TLR4 determine organotropism in metastasis2010
- Author(s)
  Tomita T., Sakurai Y., Maru Y.
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-21790330
[Presentation] Organ specific resident cells determine organotropism in metastasis2010
- Author(s)
  Tomita T., Maru Y.
- Organizer
  8th Joint Conference of the American Association for Cancer Research and the Japanese Cancer Association
- Place of Presentation
  ハワイ
- Year and Date
  2010-02-08
- Data Source
  KAKENHI-PROJECT-21790330
[Presentation] Organ specific resident cells with TLR4 determine organotropism in metastasis2010
- Author(s)
  Tomita T., Maru Y.
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-21790330
[Presentation] クララ細胞によるS100A8-SAA3-TLR4を介した肺特異的転移の機構2010
- Author(s)
  富田毅、丸義朗
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21790330
[Presentation] 肺特異的転移におけるクララ細胞の役割2009
- Author(s)
  富田毅、丸義朗
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21790330
[Presentation] 内因性TLR4リガンドによる転移前微小環境の形成
- Author(s)
  出口　敦子、富田　毅、丸　義朗
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26440063
[Presentation] Breakdown of the Eph/ephrin system in vascular endothelial cells causes lung metastasis
- Author(s)
  Ieguchi K., TOMITA T., Maru Y.
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  みやこめっせ京都
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-26440063

1. NAKAMURA Sachie (60313087)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. IKEDA-SAITO Masao (70302239)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. MATSUI Toshitaka (90323120)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 加藤真良 (70402104)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. HIROTSU Shoko (50333901)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 海野昌喜 (10359549)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MARU Yoshiro (00251447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
8. TSUKAHARA Fujiko (40119996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. DEGUCHI Atsuko (10422932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. IEGUCHI Katsuaki (90586348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. TAKITA Morichika (80533455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. FUJII Hiroshi (80228957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SHIRO Yoshitsugu (70183051)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 倉田祥一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 小井川浩之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TOMITA Takeshi 富田 毅

Research Projects

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Co-Researchers

細胞外RNA受容体ZC3H12Dの細胞内機能解析Principal Investigator

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哺乳類における細胞表面RNA結合タンパク質の解明

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細胞外RNAによる抗転移細胞活性化の解明

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抗転移細胞で特異的に発現するタンパク質の分子機序解明Principal Investigator

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Anti-metastatic cells in tumor-stimulated organs

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Biochemical characterization of an inflammation related protein, mTOC (Celastramycin binding protein)Principal Investigator

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Serum amyloid A3 and intracellular signaling protein mTOCPrincipal Investigator

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Roles of oxidized LDL receptor and TLR4 signaling in lung metastasisPrincipal Investigator

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Endogenous TLR4 ligands in tumor metastasis.

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Molecular mechanism of serum amyloid signaling in lung metastasisPrincipal Investigator

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二原子分子受容体の作用メカニズムPrincipal Investigator

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Following Heme Oxygenase Reaction at Atomic Scale

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NO-cGMP系情報伝達システムの分子機構

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TOMITA Takeshi 富田毅