kinoshita takeshi 木下健

… Alternative Names

KINOSHITA TAKESHI 木下健

木下健キノシタタケシ

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Researcher Number	20311681
Other IDs
External Links
Affiliation (Current)	2025: 金沢大学, がん進展制御研究所, 助教
Affiliation (based on the past Project Information) *help	2011 – 2013: 金沢大学, がん進展制御研究所, 助教 2007: 金沢大学, がん研究所, 助教 2006: 金沢大学, がん研究所, 助手 1999 – 2002: 金沢大学, がん研究所, 助手
Review Section/Research Field	Principal Investigator General medical chemistry / Experimental pathology Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 免疫 / シグナル伝達 / がん / 細胞内シグナル伝達 / Bid / Bclファミリー / アポトーシス Except Principal Investigator アポトーシス / 炎症 / Apaf-1様蛋白 … More / 癌 / DNAマイクロアレイ / 生体分子 / シグナル伝達 / AP-1 / ASC / がん分子標的 / リボザイム / VDAC / 単クローン抗体 / チトクロムc / yeast-two-hybrid / DR6リガンド / DR6 / Bid / ミトコンドリア / 好中球 / セリンプロテアーゼ / カスパーゼ / IL-1β / Fasリガンド / 腫瘍拒絶 Less

Identification of a novel role for innate immune sensor NLRPPrincipal Investigator
- Principal Investigator
  
  KINOSHITA TAKESHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kanazawa University
ASC依存性AP-1活性化機構の解明とASCのがん分子標的としての可能性の検討
- Principal Investigator
  
  須田貴司
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
アポトーシス促進因子Bidの制御機構Principal Investigator
- Principal Investigator
  
  木下健
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kanazawa University
アポトーシス制御にかかわる新規蛋白質の探査
- Principal Investigator
  
  須田貴司
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Fasリガンドの炎症誘導作用の分子機構の解析
- Principal Investigator
  
  須田貴司
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kanazawa University

All 2012 2011 2007 2006 Other

All Journal Article Presentation

[Journal Article] Caspase-1 protein induces apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC)-mediated necrosis independently of its catalytic activity2011
- Author(s)
  Motani K., Kushiyama H., Imamura R., Kinoshita, T., Nishiuchi T., Suda T.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 33963-33972
- NAID
  120003479727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590327
[Journal Article] Caspase-1 protein induces apoptosis-associated speck-like protein containing a caspase recruit ment domain(ASC)-mediated necrosis ind ependently of its catalytic activity2011
- Author(s)
  Motani, K., Kushiyama, H., Imamura, R., et. al.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Issue: 39 Pages: 33963-33972
- DOI
  10.1074/jbc.m111.286823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590329, KAKENHI-PUBLICLY-23114505, KAKENHI-PROJECT-23390092, KAKENHI-PROJECT-23590327
[Journal Article] Fas-associated Factor 1 is a negative regulator of PYRIN-containing Apaf-1-like protein 12006
- Author(s)
  Kinoshita Takeshi
- Journal Title
  
  Int.Immunol. 18
  
  Pages: 1701-1706
- NAID
  10018673882
- Data Source
  KAKENHI-PROJECT-18013022
[Presentation] The role of NLRP3 in the induction of cytokine gene expression in tumor cells2012
- Author(s)
  木下健, 今村龍, 須田貴司
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-23590327
[Presentation] NLRP3 mediates NF-B activation and cytokine induction in microbially induced and sterile inflammation2011
- Author(s)
  木下健, 今村龍, 須田貴司
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-23590327
[Presentation] Flagellin刺激下のヒトマクロファージ様細胞株におけるASC非依存的な…2007
- Author(s)
  木下健
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18013022
[Presentation] NLRP3 mediates NF-κB activation and cytokine induction in microbially induced and sterile inflammation
- Author(s)
  Takeshi Kinoshita, Ryu Imamura, Takashi Suda
- Organizer
  第３４回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Data Source
  KAKENHI-PROJECT-23590327
[Presentation] The role for NLRP3 in the induction of cytokine gene expression in tumor cells
- Author(s)
  akeshi Kinoshita, Ryu Imamura, Takashi Suda
- Organizer
  第35回に本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23590327

1. 須田貴司 (70250090)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 今村龍 (10311680)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results

kinoshita takeshi 木下 健

KINOSHITA TAKESHI 木下 健

木下 健 キノシタ タケシ

Research Projects

Research Products

Co-Researchers

Identification of a novel role for innate immune sensor NLRPPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ASC依存性AP-1活性化機構の解明とASCのがん分子標的としての可能性の検討

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

アポトーシス促進因子Bidの制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アポトーシス制御にかかわる新規蛋白質の探査

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Fasリガンドの炎症誘導作用の分子機構の解析

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] Caspase-1 protein induces apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC)-mediated necrosis independently of its catalytic activity2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Caspase-1 protein induces apoptosis-associated speck-like protein containing a caspase recruit ment domain(ASC)-mediated necrosis ind ependently of its catalytic activity2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fas-associated Factor 1 is a negative regulator of PYRIN-containing Apaf-1-like protein 12006

Author(s)

Journal Title

NAID

Data Source

[Presentation] The role of NLRP3 in the induction of cytokine gene expression in tumor cells2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] NLRP3 mediates NF-B activation and cytokine induction in microbially induced and sterile inflammation2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Flagellin刺激下のヒトマクロファージ様細胞株におけるASC非依存的な…2007

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] NLRP3 mediates NF-κB activation and cytokine induction in microbially induced and sterile inflammation

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] The role for NLRP3 in the induction of cytokine gene expression in tumor cells

Author(s)

Organizer

Place of Presentation

Data Source

kinoshita takeshi 木下健

KINOSHITA TAKESHI 木下健

木下健キノシタタケシ