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KUMAGAI Hiroyuki  熊谷 啓之

ORCIDConnect your ORCID iD *help
Researcher Number 20321945
Affiliation (based on the past Project Information) *help 2011: 東北大学, 医学(系)研究科(研究院), 助教
2010 – 2011: 東北大学, 大学院・医学系研究科, 助教
2007: Tohoku University, 先進医工学研究機構, 准教授
2006: 東北大学, 先進医学研究機構, 助教授
2004 – 2006: 東北大学, 先進医工学研究機構, 助教授 … More
2004: 群馬大学, 医学系研究科, 助手
2004: Gunma University, Graduate School of Medicine, Research Associate, 大学院・医学系研究科, 助手
2001 – 2003: 群馬大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Experimental pathology / Circulatory organs internal medicine / Biological Sciences / General pharmacology / General pharmacology
Except Principal Investigator
Biological Sciences / General pharmacology / Cell biology / General pharmacology / Neurochemistry/Neuropharmacology
Keywords
Principal Investigator
血管平滑筋 / 心不全 / 核内移行 / シグナル伝達 / 形質転換 / 収縮力 / ミオシン / 不整脈 / 再生医療 / 筋芽細胞 … More / 再生治療 / 心筋 / 再生医学 / 遺伝子治療 / 分子機序 / 骨化シグナル / 動脈壁硬化 / 動脈硬化 / アクトミオシン / 収縮 / 血管平滑筋細胞 / トロポミオシン / 遊走 / GFP融合 / レトロウイルスベクター / クローニング / 核移行 / 血小板由来増殖因子 / 血小板由来成長因子 … More
Except Principal Investigator
アクチン / ミオシン / ファシン / 平滑筋 / ドレブリン / フィロポディア / migration / Regulation / smooth muscle / Myosin / Actin / 血小板成長因子 / ブレビスタチン / リン酸化 / 循環器・高血圧 / 蛋白質 / 薬理学 / 遊走 / 制御 / drebrin / fascin / actin-binding protein / tropomyosin / actin / アクチン結合蛋白質 / トロポミオシン / down-regulation / myosin light chain kinase / myosin / regulation / Smooth muscle / 遺伝子ノックアウト / ミオシン軽鎖キナーゼ / 収縮制御 / ミオシンV / 成長円錐 / Ca測定 / カプサイシン / 発現 / cDNA / 受容体分布 / バニロイド受容体 Less
  • Research Projects

    (12 results)
  • Research Products

    (8 results)
  • Co-Researchers

    (9 People)
  •  Development of a novel technique for myoblast transplantation that is capable of preventing life-threatening arrhythmias and of dramatically restoring cardiac contractilityPrincipal Investigator

    • Principal Investigator
      KUMAGAI Hiroyuki
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Tohoku University
  •  心不全重症化の分子機序解明と、それに基づく遺伝子治療法開発Principal Investigator

    • Principal Investigator
      熊谷 啓之
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tohoku University
  •  血管平滑筋細胞の遊走につながるシグナル伝達経路の解明Principal Investigator

    • Principal Investigator
      熊谷 啓之
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  カルシウムによる成長円錐運動制御機構の解析(2)

    • Principal Investigator
      石川 良樹
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  A novel regulatory way of smooth muscle contraction

    • Principal Investigator
      KOHAMA Kazuhiro
    • Project Period (FY)
      2004 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General pharmacology
    • Research Institution
      Gunma University
  •  カルシウムによる成長円錐運動制御機構の解析

    • Principal Investigator
      石川 良樹
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  血管平滑筋細胞遊走につながるシグナル伝達経路の解明Principal Investigator

    • Principal Investigator
      熊谷 啓之
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      Tohoku University
      Gunma University
  •  How differential distributions of actin-bindingproteins are formed in living cells.

    • Principal Investigator
      ISHIKAWA Ryoki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Gunma University
  •  神経成長円錐と経路選択:ミオシン-Vの役割を探る(II)

    • Principal Investigator
      ISHIKAWA Ryoki
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  血管平滑筋細胞を収縮型から合成型へ転換させるシグナル伝達経路の解明Principal Investigator

    • Principal Investigator
      熊谷 啓之
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      Gunma University
  •  神経細胞膜の裏打ちをするアクトミオシン系蛋白質は受容体機能の制御因子たり得るか?

    • Principal Investigator
      小浜 一弘
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Gunma University
  •  Smooth muscle regulation

    • Principal Investigator
      KOHAMA Kazuhiro
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General pharmacology
    • Research Institution
      Gunma University

All 2011 2008 2006 2005

All Journal Article Presentation Patent

  • [Journal Article] Intracellular Signal Transduction For Migration and Actin Remodeling In Vascular Smooth Muscle Cells After Sphingosylphosphorylcholine Stimulation2006

    • Author(s)
      Li S., Tanaka H., Wang H-H., Yoshiyama S., Kumagai H., Nakamura A., Brown D-L., Thatcher S-E., Wright G-L., and Kohama K.
    • Journal Title

      Am. J. Physiol. Heart Circ. Physiol 291

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209007
  • [Journal Article] Intracellular signal transduction for migration and actin remodeling in vascular smooth muscle cells after sphingosylphosphorylcholine stimulation.2006

    • Author(s)
      Li, S., Tanaka, H., Wang, H-H., Yoshiyama, S., Kumagai, H., Nakamura, A., Brouwn, D-L., Thatceher, S-E., Wright, G-L., Kohama,K.
    • Journal Title

      Am. J. Physiol. (Heart & Circulatory Physiol.) 291

    • Data Source
      KAKENHI-PROJECT-16209007
  • [Journal Article] Intracellular Signal Transduction For Migration and Actin Remodeling In Vascular Smooth Muscle Cells After Sphingosylphosphorylcholine Stimulation.2006

    • Author(s)
      Li S., Tanaka H., Wang H-H., Yoshiyama S., Kumagai H., Nakamura A., Brown D-L., Thatcher S-E., Wright G-L., and Kohama K.
    • Journal Title

      Am. J. Physiol. Heart Circ. Physiol. 291

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16209007
  • [Journal Article] A common molecular pathogenesis of heart failure.2006

    • Author(s)
      Kumagai, H., et al.
    • Journal Title

      New Trends in Research, Diagnosis, and Treatment (in press)

    • Data Source
      KAKENHI-PROJECT-17049001
  • [Patent] シグナル依存性核内移行蛋白群のクローニング方法2005

    • Inventor(s)
      熊谷 啓之, 豊岡 照彦
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Filing Date
      2005-10-24
    • Data Source
      KAKENHI-PROJECT-17049001
  • [Presentation] 不整脈予防と心収縮力の著明な改善を同時に実現した、新しい筋芽細胞移植法2011

    • Author(s)
      熊谷啓之
    • Organizer
      第33回心筋生検研究会
    • Place of Presentation
      京都大学百周年時計台記念館(京都府)
    • Year and Date
      2011-11-25
    • Data Source
      KAKENHI-PROJECT-22790373
  • [Presentation] 不整脈予防と心収縮力の著明な改善を同時に実現した、新しい筋芽細胞移植法2011

    • Author(s)
      熊谷啓之、高松哲郎、戴平
    • Organizer
      第33回心筋生検研究会
    • Place of Presentation
      京都
    • Year and Date
      2011-11-25
    • Data Source
      KAKENHI-PROJECT-22790373
  • [Presentation] A crucial modulator of BMP signaling that may have roles in the development of IPAH2008

    • Author(s)
      Hiroyuki Kumagai
    • Organizer
      The 1st International Symposium of Pulmonary Hypertension
    • Place of Presentation
      仙台
    • Year and Date
      2008-03-19
    • Data Source
      KAKENHI-PROJECT-18689019
  • 1.  ISHIKAWA Ryoki (20212863)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  KOHAMA Kazuhiro (30101116)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 3 results
  • 3.  NAKAMURA Akio (30282388)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 4.  YOSHIYAMA Shinji (30396650)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  TANAKA Hideyuki (70343085)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  NASU Ritsuko (60383147)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  宮崎 淳一 (80229830)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  大石 一彦 (80203701)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  登坂 雅彦 (40323357)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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