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Hirayama Aki  平山 暁

… Alternative Names

HIRAYAMA Aki  平山 暁

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Researcher Number 20323298
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-5777-4208
Affiliation (Current) 2025: 筑波技術大学, その他部局等, 名誉教授
Affiliation (based on the past Project Information) *help 2009 – 2022: Tsukuba University of Technology, 保健科学部, 教授
2010: 筑波技術大学, 保健科学部, 特任教授
2007 – 2008: Tsukuba University of Technology, Faculty of Health Sceinces, Professor
2006: 筑波大学, 大学院人間総合科学研究科, 講師
2004: 筑波大学, 大学院・人間総合科学研究科, 講師
2001 – 2003: 筑波大学, 臨床医学系, 講師
Review Section/Research Field
Principal Investigator
Kidney internal medicine / Basic Section 52010:General internal medicine-related / Rehabilitation science/Welfare engineering / Kidney internal medicine
Except Principal Investigator
Neurosurgery / Basic Section 56010:Neurosurgery-related / Basic Section 52020:Neurology-related / Medium-sized Section 9:Education and related fields / Applied health science / Kidney internal medicine / General pharmacology
Keywords
Principal Investigator
酸化ストレス / 電子スピン共鳴 / 慢性腎臓病 / ナノ粒子 / 一酸化窒素 / Nrf2 / 東洋医学 / 漢方 / MULTIS / 多種ラジカル消去活性測定(MULTIS) … More / 一酸化窒素合成酵素 / 微小循環 / ライブイメージング / 抗酸化効果 / 補腎剤 / 血流速度 / 細動脈 / 毛細血管 / 桂枝茯苓丸 / 牛車腎気丸 / QOL / 多種ラジカル消去活性(MULTIS) / 運動療法 / 血液透析 / 腎臓リハビリテーション / Oxidative Stress / Angiotensin II Receptor Antagonist / Ca Channel Antagonist / Hypertension / Electron Paramagnetic Resonance Imaging / Electron Paramagnetic Resonance / アンジオテンシンレセプター拮抗薬 / カルシウム拮抗薬 / 高血圧性腎障害 / 高血圧 / 硬化性被嚢性腹膜炎 / 腹膜透析 / ナノメディシン / DDS(Drug Delivery System) / TEMPO / 腎保護薬 / ドラッグデリバリーシステム / 急性腎障害 / phosphatidylcholine hydroperoxide / 糖尿病性腎症 / 虚血再潅流急性腎不全 / スピンプローブ / ESR(EPR)イメージング / フリーラジカル / 抗酸化能 / Nrf2遺伝子欠損マウス / in vivo ESR / ESRイメージング / リポポリサッカライド / Carbamoyl-PROXYL / ループス腎炎 … More
Except Principal Investigator
酸化ストレス / フリーラジカル / 脳梗塞 / 細胞認識性カドヘリンマトリックス / 口腔内間葉組織由来神経系細胞 / 神経再生 / 歯髄 / 細胞保護 / 再生医療 / レドックスナノ粒子 / 神経系細胞 / 歯髄幹細胞 / 認知症 / PETイメージング / タウ / アルツハイマー病 / 社会性 / 自閉症 / 脳血管障害学 / 脳神経外科学 / ナノ粒子化活性酸素消去剤 / 血液脳関門 / 神経血管ユニット保護 / 血栓回収療法 / RNP / 脳保護 / ナノ粒子 / 活性酸素 / 脳保護療法 / 脳虚血再灌流障害 / 透析効率 / 負荷量可変型自転車 / 電動アシスト自転車 / 腎臓リハビリテーション / 血液透析患者 / 慢性腎不全患者 / RCT / 電動式エルゴメータ / 負荷量可変型エルゴメータ / 外来透析 / 生化学検査 / 身体運動機能 / 有効性 / 安全性 / 透析中の電気刺激 / 透析中の運動療法 / 維持透析 / 生化学変化 / 筋力 / 運動耐容能 / 運動様式 / 透析中の運動 / 血液透析 / 慢性腎不全 / 高齢者 / RABBIT MODEL OF LIGHT SHIELDED HEMODIALYSIS / NO OVERPRODUCTION / ENDOTHELIAL NOS / SINGLET OXYGEN / PLASMA LIPID PEROXIDES / DIALYZER / ULTRAVIOLET CUT FILM / LIGHT SHIELDED HEMODIALYSIS / 抗酸化能 / PCOOH / TBARS / 過酸化脂質 / 一酸化窒素 / UVカット透析 / 光遮断血液回路 / ウサギの遮光透析モデル / NO過剰産生 / 内皮型NOS / 1重項酸素 / 血中過酸化脂質 / ダイアライザー / 紫外線除去フィルム / 遮光透析 / 細胞周期 / がん幹細胞 / 電子スピン共鳴 / 癌幹細胞 / 脳腫瘍額 / Radiation / Cell Cycle / Cancer Stem Cell / Electron Spin Resonance / 薬理学 / シグナル伝達 / 循環器・高血圧 / 糖尿病 Less
  • Research Projects

    (15 results)
  • Research Products

    (149 results)
  • Co-Researchers

    (47 People)
  •  Comprehensive PET imaging for oxidative stress and tau to clarify the pathogenesis of Alzheimer's disease

    • Principal Investigator
      Ikawa Masamichi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      University of Fukui
  •  Development of regenerative medicine for ischemic stroke using redox nanoparticles and oral mesenchymal tissue-derived neuronal cells

    • Principal Investigator
      Marushima Aiki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      University of Tsukuba
  •  The bioenergetic dysfunction in ASD focusing on free radicals

    • Principal Investigator
      MATSUZAKI HIDEO
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 9:Education and related fields
    • Research Institution
      University of Fukui
  •  Analysis of antioxidative mechanism of "Hojin-zai", a traditional Kampo medicine, and it application to the new prooxidant therapy.Principal Investigator

    • Principal Investigator
      Hirayama Aki
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Tsukuba University of Technology
  •  Development of neurovascular unit protection therapy for cerebral ischemia-reperfusion injury by redox nanopartices

    • Principal Investigator
      Marushima Aiki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      University of Tsukuba
  •  Effects of a renal rehabilitation exercise program in elderly patients with chronic renal falure

    • Principal Investigator
      Miura Misa
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Tsukuba University of Technology
  •  Renal rehabilitation program oriented to oxidative stress controlPrincipal Investigator

    • Principal Investigator
      Hirayama Aki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Tsukuba University of Technology
  •  Electron spin resonance live imaging for the metabolism and migration of radio-resistant brain tumor cells

    • Principal Investigator
      MORITAKE Takashi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurosurgery
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Development of functional redox nanoparticle for long-term peritoneal dialysisPrincipal Investigator

    • Principal Investigator
      AKI HIRAYAMA
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tsukuba University of Technology
  •  Development of an antioxidative nano-particle for redox sensoring and reno-protectionPrincipal Investigator

    • Principal Investigator
      HIRAYAMA Aki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tsukuba University of Technology
  •  Study on roles of a novel NADPH oxidase isoform in the development of lifestyle related diseases

    • Principal Investigator
      YABE Chihiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Non-invasive Redox Imaging for the Pathophysiological Analysis of Hypertensive Renal Disease and Development of Antioxidative TherapyPrincipal Investigator

    • Principal Investigator
      HIRAYAMA Aki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tsukuba University of Technology
      University of Tsukuba
  •  腎疾患における生体内酸化ストレス動態の非侵襲的画像化解析と抗酸化療法への応用Principal Investigator

    • Principal Investigator
      平山 暁
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      University of Tsukuba
  •  Development of New Method of Hemodialysis Using Light Shielded Dialyzer and Blood Circuit

    • Principal Investigator
      NAGASE Sohji
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      University of Tsukuba
  •  in vivo 3次元ESRによる腎疾患モデル動物の生体内酸化・抗酸化動態解析Principal Investigator

    • Principal Investigator
      平山 暁
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      University of Tsukuba

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

  • [Book] Application of EPR Imaging to the Pathophysiological Analysis of Acute Renal Failure and Antioxidative Effects of Erythropoietin. In The Proceedings of the 12th Biennial Meeting of the Society for Free Radical Research International.2005

    • Author(s)
      Hirayama A.et al.(edited by Boveris A.et al.)
    • Total Pages
      395
    • Publisher
      Medimond S.r.l.(Bologna, Italy)
    • Data Source
      KAKENHI-PROJECT-15790427
  • [Book] 腎とフリーラジカル 第7集・ESRイメージングによる腎抗酸化能変化のin vivo無侵襲定量解析法の確立とエリスロポエチンによる臓器保護効果測定への応用2004

    • Author(s)
      平山 暁 他
    • Total Pages
      190
    • Publisher
      東京医学社・東京
    • Data Source
      KAKENHI-PROJECT-15790427
  • [Journal Article] Regional cortical hypoperfusion and atrophy correlate with striatal dopaminergic loss in Parkinson's disease: a study using arterial spin labeling MR perfusion.2023

    • Author(s)
      Kitazaki Y, Ikawa M, Yamaguchi T, Enomoto S, Shirafuji N, Yamamura O, Tsujikawa T, Okazawa H, Kimura H, Nakamoto Y, Hamano T.
    • Journal Title

      Neuroradiology

      Volume: 65 Issue: 3 Pages: 569-577

    • DOI

      10.1007/s00234-022-03085-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07392, KAKENHI-PROJECT-22K19505, KAKENHI-PROJECT-20K07900, KAKENHI-PROJECT-23K24278
  • [Journal Article] Live-Imaging Analysis of Target Vessels and Nitric Oxide Production Associated with Gosha-Jinki-Gan and Keishi-Bukuryo-Gan: Two Herbal Preparations with Clinically Proven Blood Flow-Improving Effects but with Different Traditional Clinical Indicative Patterns2022

    • Author(s)
      Hirayama Aki、Tomita Tsutomu、Nishida Takashi、Nagano Yumiko
    • Journal Title

      Evidence-Based Complementary and Alternative Medicine

      Volume: 2022 Pages: 1-10

    • DOI

      10.1155/2022/3821345

    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Journal Article] A Ruptured Aneurysm in Aplastic or Twig-like Middle Cerebral Artery: A Case Report with Histological Investigation2022

    • Author(s)
      WATANABE Noriyuki、MARUSHIMA Aiki、HINO Tenyu、MINAMIMOTO Shinya、SATO Masayuki、ITO Yoshiro、HAYAKAWA Mikito、SAKAMOTO Noriaki、ISHIKAWA Eiichi、MATSUMURA Akira、MATSUMARU Yuji
    • Journal Title

      NMC Case Report Journal

      Volume: 9 Issue: 0 Pages: 7-12

    • DOI

      10.2176/jns-nmc.2021-0276

    • NAID

      130008163361

    • ISSN
      2188-4226
    • Year and Date
      2022-12-31
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09450, KAKENHI-PROJECT-20H03787
  • [Journal Article] Cerebral Oxidative Stress in Early Alzheimer’s Disease Evaluated by 64Cu-ATSM PET/MRI: A Preliminary Study2022

    • Author(s)
      Okazawa Hidehiko、Ikawa Masamichi、Tsujikawa Tetsuya、Mori Tetsuya、Makino Akira、Kiyono Yasushi、Nakamoto Yasunari、Kosaka Hirotaka、Yoneda Makoto
    • Journal Title

      Antioxidants

      Volume: 11 Issue: 5 Pages: 1022-1022

    • DOI

      10.3390/antiox11051022

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19505, KAKENHI-PROJECT-20K07900, KAKENHI-PROJECT-23K24278
  • [Journal Article] Antiplatelet Therapy and Periprocedural Risk Factor Analysis for Pipeline Embolization Device Treatment of Unruptured Internal Carotid Artery Aneurysms: A Retrospective, Multicenter Analysis2022

    • Author(s)
      Hosoo Hisayuki、Ishikawa Eiichi、Tsuruta Wataro、Sato Masayuki、Ito Yoshiro、Hayakawa Mikito、Takigawa Tomoji、Marushima Aiki、Suzuki Kensuke、Hyodo Akio、Matsumaru Yuji
    • Journal Title

      World Neurosurgery

      Volume: 157 Pages: e102-e110

    • DOI

      10.1016/j.wneu.2021.09.109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03787
  • [Journal Article] Time-sequential Changes in Antioxidant Profile during Aging Process2022

    • Author(s)
      Hirayama Aki、Nagano Yumiko、Oowada Shigeru、Matsuzaki Hideo
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 180 Pages: s22-s22

    • DOI

      10.1016/j.freeradbiomed.2021.12.042

    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Journal Article] Induced Neural Cells from Human Dental Pulp Ameliorate Functional Recovery in a Murine Model of Cerebral Infarction2021

    • Author(s)
      Matsumura Hideaki、Marushima Aiki、Ishikawa Hiroshi、Toyomura Junko、Ohyama Akihiro、Watanabe Miho、Takaoka Shohei、Bukawa Hiroki、Matsumura Akira、Matsumaru Yuji、Ishikawa Eiichi
    • Journal Title

      Stem Cell Reviews and Reports

      Volume: 18 Issue: 2 Pages: 595-608

    • DOI

      10.1007/s12015-021-10223-w

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09450, KAKENHI-PROJECT-20H03787
  • [Journal Article] Ttansplanted neural lineage cells derived from dental pulp stem cells promote peripheral nerve regeneration2021

    • Author(s)
      Shohei Takaoka, Fumihiko Uchida, Hiroshi Ishikawa, Junko Toyomura, Akihiro Ohyama, Miho Watanabe, Hideki Matsumura, Aiki Marushima, Seiichiro Iizumi, Satoshi Fukuzawa, Naomi Ishibashi-Kanno, Kenji Yamagata, Toru Yanagawa, Yuji Matsumura, Hiroki Bukawa
    • Journal Title

      Hum Cell

      Volume: 35 Issue: 2 Pages: 462-471

    • DOI

      10.1007/s13577-021-00634-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07860, KAKENHI-PROJECT-21K11668, KAKENHI-PROJECT-20H03787
  • [Journal Article] Hemodialysis raises oxidative stress through carbon-centered radicals despite improved biocompatibility2021

    • Author(s)
      Hirayama Aki、Akazaki Satomi、Nagano Yumiko、Ueda Atsushi、Chang-il Lee Masaichi、Aoyagi Kazumasa、Oowada Shigeru、Sato Keizo
    • Journal Title

      Journal of Clinical Biochemistry and Nutrition

      Volume: 69 Issue: 1 Pages: 44-51

    • DOI

      10.3164/jcbn.20-141

    • NAID

      130008060394

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Journal Article] ライブイメージングによる,桃核承気湯,桂枝茯苓丸,当帰芍薬散の微小循環動態への特性評価2020

    • Author(s)
      平山 暁,富田 勉,横田 廣夫,笠巻 祐二,松﨑 靖司,青柳 一正.
    • Journal Title

      日本東洋医学雑誌

      Volume: 71 Pages: 8-17

    • NAID

      130007869073

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Journal Article] VLDL-specific increases of fatty acids in autism spectrum disorder correlate with social interaction.2020

    • Author(s)
      Usui N, Toyoshima M et al.
    • Journal Title

      EBioMedicine

      Volume: 58 Pages: 102917-102917

    • DOI

      10.1016/j.ebiom.2020.102917

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08023, KAKENHI-PROJECT-20K07823, KAKENHI-PROJECT-19H03581, KAKENHI-PROJECT-20H03595, KAKENHI-PROJECT-19K21754, KAKENHI-PROJECT-18K07578
  • [Journal Article] A potential role of fatty acid binding protein 4 in the pathophysiology of autism spectrum disorder.2020

    • Author(s)
      Maekawa M, Ohnishi T, Toyoshima M, Shimamoto-Mitsuyama C, Hamazaki K, Balan S, Wada Y, Esaki K, Takagai S, Tsuchiya KJ, Nakamura K, Iwata Y, Nara T, Iwayama Y, Toyota T, Nozaki Y, Ohba H, Watanabe A, Hisano Y, Matsuoka S, Tsujii M, Mori N, Matsuzaki H, Yoshikawa T.
    • Journal Title

      Brain Communication

      Volume: 2(2) Issue: 2

    • DOI

      10.1093/braincomms/fcaa145

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03581, KAKENHI-PROJECT-20H03595, KAKENHI-PROJECT-19K21754, KAKENHI-PROJECT-18K07578
  • [Journal Article] Simultaneous evaluation of antioxidative serum profiles facilitates the diagnostic screening of autism spectrum disorder in under-6-year-old children2020

    • Author(s)
      Hirayama Aki、Wakusawa Keisuke、Fujioka Toru、Iwata Keiko、Usui Noriyoshi、Kurita Daisuke、Kameno Yosuke、Wakuda Tomoyasu、Takagai Shu、Hirai Takaharu、Nara Takahiro、Ito Hiromu、Nagano Yumiko、Oowada Shigeru、Tsujii Masatsugu、Tsuchiya Kenji J.、Matsuzaki Hideo
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 20602-20602

    • DOI

      10.1038/s41598-020-77328-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07437, KAKENHI-PROJECT-19H03581, KAKENHI-PROJECT-19K21754
  • [Journal Article] Antioxidant nanomedicine with cytoplasmic distribution in neuronal cells shows superior neurovascular protection properties2020

    • Author(s)
      Mujagic Arnela、Marushima Aiki、Nagasaki Yukio、Hosoo Hisayuki、Hirayama Aki、Puentes Sandra、Takahashi Toshihide、Tsurushima Hideo、Suzuki Kensuke、Matsui Hirofumi、Ishikawa Eiichi、Matsumaru Yuji、Matsumura Akira
    • Journal Title

      Brain Research

      Volume: 1743 Pages: 146922-146922

    • DOI

      10.1016/j.brainres.2020.146922

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H05458, KAKENHI-PROJECT-20H03787
  • [Journal Article] Novel neuroprotection using antioxidant nanoparticles in a mouse model of head trauma2020

    • Author(s)
      Takahashi Toshihide、Marushima Aiki、Nagasaki Yukio、Hirayama Aki、Muroi Ai、Puentes Sandra、Mujagic Arnela、Ishikawa Eiichi、Matsumura Akira
    • Journal Title

      Journal of Trauma and Acute Care Surgery

      Volume: - Issue: 5 Pages: 1-1

    • DOI

      10.1097/ta.0000000000002617

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19725, KAKENHI-PROJECT-17K10819, KAKENHI-PROJECT-20H03787
  • [Journal Article] Evaluation of Various Anti-<i>oketsu </i>Kampo Formulae—Tokakujokito,Keishibukuryogan and Tokishakuyakusan—for Microcirculation by Live Imaging2020

    • Author(s)
      HIRAYAMA Aki、TOMITA Tsutomu、YOKOTA Hiroo、KASAMAKI Yuji、MATSUZAKI Yasushi、AOYAGI Kazumasa
    • Journal Title

      Kampo Medicine

      Volume: 71 Issue: 1 Pages: 8-17

    • DOI

      10.3937/kampomed.71.8

    • NAID

      130007869073

    • ISSN
      0287-4857, 1882-756X
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Journal Article] Noninvasive Measurement of [11C]PiB Distribution Volume Using Integrated PET/MRI2020

    • Author(s)
      Okazawa Hidehiko、Ikawa Masamichi、Tsujikawa Tetsuya、Makino Akira、Mori Tetsuya、Kiyono Yasushi、Kosaka Hirotaka
    • Journal Title

      Diagnostics

      Volume: 10 Issue: 12 Pages: 993-993

    • DOI

      10.3390/diagnostics10120993

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07900, KAKENHI-PROJECT-18H02763
  • [Journal Article] Increased plasma lipoprotein lipase activity in males with autism spectrum disorder.2020

    • Author(s)
      Hirai T, Usui N, Iwata K, Miyachi T, Tsuchiya KJ, Xie MJ, Nakamura K, Tsujii M, Sugiyama T, Matsuzaki H*.
    • Journal Title

      Research in Autism Spectrum Disorders

      Volume: 77 Pages: 101630-101630

    • DOI

      10.1016/j.rasd.2020.101630

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03581, KAKENHI-PROJECT-19K21754
  • [Journal Article] Encapsulation of tissue plasminogen activator in pH-sensitive self-assembled antioxidant nanoparticles for ischemic stroke treatment ? Synergistic effect of thrombolysis and antioxidant ?2019

    • Author(s)
      Mei Ting、Kim Ahram、Vong Long Binh、Marushima Aiki、Puentes Sandra、Matsumaru Yuji、Matsumura Akira、Nagasaki Yukio
    • Journal Title

      Biomaterials

      Volume: 215 Pages: 119209-119209

    • DOI

      10.1016/j.biomaterials.2019.05.020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Journal Article] The visualization methods of occluded dural sinus for safe transvenous embolization of dural AVFs2019

    • Author(s)
      Hosoo H, Tsuruta W, Nakai Y, Shiigai M, Sato M, Ito Y, Takigawa T, Marushima A, Ishikawa E, Yamamoto T, Matsumaru Y, Matsumura A.
    • Journal Title

      World Neurosurgery

      Volume: 印刷中 Pages: e337-e345

    • DOI

      10.1016/j.wneu.2019.02.250

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Journal Article] Effectiveness of Near-Infrared Spectroscopy (NIRO-200NX, Pulse Mode) for Risk Management in Carotid Artery Stenting2019

    • Author(s)
      Terakado Toshitsugu、Marushima Aiki、Koyama Yasuaki、Tsuruta Wataro、Takigawa Tomoji、Ito Yoshiro、Hino Tenyu、Sato Masayuki、Hayakawa Mikito、Ishikawa Eiichi、Inoue Yoshiaki、Matsumaru Yuji、Matsumura Akira
    • Journal Title

      World Neurosurgery

      Volume: 131 Pages: e425-e432

    • DOI

      10.1016/j.wneu.2019.07.184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Journal Article] Clinical Characteristics and Endovascular Treatment for Spinal Dural Arteriovenous Fistula in Japan: Japanese Registry of Neuroendovascular Therapy 2 and 32019

    • Author(s)
      TSURUTA Wataro、MATSUMARU Yuji、IIHARA Koji、SATOW Tetsu、SAKAI Nobuyuki、KATSUMATA Masahiro、HOSOO Hisayuki、SATO Masayuki、ITO Yoshiro、MARUSHIMA Aiki、HAYAKAWA Mikito、ISHIKAWA Eiichi、MATSUMURA Akira
    • Journal Title

      Neurol. Med. Chir.(Tokyo)

      Volume: 59 Issue: 12 Pages: 492-497

    • DOI

      10.2176/nmc.st.2018-0218

    • NAID

      130007761491

    • ISSN
      0470-8105, 1349-8029
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Journal Article] Treatment Strategy Based on Plaque Vulnerability and the Treatment Risk Evaluation for Internal Carotid Artery Stenosis2018

    • Author(s)
      ITO Yoshiro、TSURUTA Wataro、NAKAI Yasunobu、TAKIGAWA Tomoji、MARUSHIMA Aiki、MASUMOTO Tomohiko、MATSUMARU Yuji、ISHIKAWA Eiichi、MATSUMURA Akira
    • Journal Title

      Neurol. Med. Chir.(Tokyo)

      Volume: 58 Issue: 5 Pages: 191-198

    • DOI

      10.2176/nmc.oa.2017-0228

    • NAID

      130006734354

    • ISSN
      0470-8105, 1349-8029
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Journal Article] Preliminary in vivo magnetofection data using magnetic calcium phosphate nanoparticles immobilizing DNA and iron oxide nanocrystals2018

    • Author(s)
      Shubhra Quazi T.H.、Oyane Ayako、Nakamura Maki、Puentes Sandra、Marushima Aiki、Tsurushima Hideo
    • Journal Title

      Data in Brief

      Volume: 18 Pages: 1696-1701

    • DOI

      10.1016/j.dib.2018.04.058

    • NAID

      120007128503

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819, KAKENHI-PROJECT-16H03831
  • [Journal Article] 症例 鼻出血で発症した海綿静脈洞部内頚動脈解離性動脈瘤の1例2018

    • Author(s)
      Kino H, Tsuruta W, Ito Y, Takigawa T, Shiigai M, Marushima A, Nakai Y, Yamamoto T, Matsumura A
    • Journal Title

      Neurological Surgery 脳神経外科

      Volume: 46 Issue: 9 Pages: 789-795

    • DOI

      10.11477/mf.1436203815

    • ISSN
      0301-2603, 1882-1251
    • Year and Date
      2018-09-10
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Journal Article] Clinical significance of redox effects of Kampo formulae, a traditional Japanese herbal medicine: comprehensive estimation of multiple antioxidative activities2018

    • Author(s)
      Hirayama Aki、Oowada Shigeru、Ito Hiromu、Matsui Hirofumi、Ueda Atsushi、Aoyagi Kazumasa
    • Journal Title

      Journal of Clinical Biochemistry and Nutrition

      Volume: 62 Issue: 1 Pages: 39-48

    • DOI

      10.3164/jcbn.17-59

    • NAID

      130006301228

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Journal Article] Spinal Cord Infarction in the Region of the Posterior Spinal Artery After Embolization for Vertebral Artery Dissection2018

    • Author(s)
      Tsuruta Wataro、Yamamoto Tetsuya、Ikeda Go、Sato Masayuki、Ito Yoshiro、Takigawa Tomoji、Marushima Aiki、Nakai Yasunobu、Matsumaru Yuji、Matsumura Akira
    • Journal Title

      Operative Neurosurgery

      Volume: 15 Issue: 6 Pages: 701-710

    • DOI

      10.1093/ons/opy026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Journal Article] Exercise Program for Chronic Kidney Disease Improves Pathophysiological Condition with a Shift of Oxidative Stress2017

    • Author(s)
      Hirayama Aki、Miura Misa、Yasuda Go、Nagano Yumiko、Matsui Hirofumi、Hirayama Yoh、Ueda Atsushi、Aoyagi Kazumasa、Kohzuki Masahiro、Oowada Shigeru
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 112 Pages: 131-132

    • DOI

      10.1016/j.freeradbiomed.2017.10.200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Journal Article] Intensive Gait Treatment Using a Robot Suit Hybrid Assistive Limb in Acute Spinal Cord Infarction: Report of Two Cases2017

    • Author(s)
      Watanabe H, Marushima A, Kawamoto H, Kadone H, Ueno T, Shimizu Y, Endo A, Hada Y, Saotome K, Abe T, Yamazaki M, Sankai Y, Ishikawa E, Matsumura A
    • Journal Title

      J Spinal Cord Med

      Volume: 9 Issue: 3 Pages: 1-7

    • DOI

      10.1080/10790268.2017.1372059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Journal Article] 視覚障害学生に対する喀痰吸引モデル使用の経験2017

    • Author(s)
      三浦美佐,上月正博,松下昌之助,平山暁,石塚和重
    • Journal Title

      ロービジョン学会誌

      Volume: 1 Pages: 1-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Journal Article] Training with an Electric Exercise Bike versus a Conventional Exercise Bike during Hemodialysis for Patients with End-stage Renal Disease: A Randomized Clinical Trial2017

    • Author(s)
      Miura M, Yoshizawa R, Oowada S, Hirayama A, Ito O, Kohzuki M, Maeba T.
    • Journal Title

      Progress in Rehabilitation Medicine

      Volume: 2 Issue: 0 Pages: n/a

    • DOI

      10.2490/prm.20170008

    • NAID

      130007042064

    • ISSN
      2432-1354
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H02118, KAKENHI-PROJECT-15K01702, KAKENHI-PROJECT-15K12575
  • [Journal Article] Improving the neurological prognosis following OHCA using real-time evaluation of cerebral tissue oxygenation: a case report2017

    • Author(s)
      Koyama Y, Inoue Y, Hisago S, Marushima A, Hagiya K, Yamasaki Y, Enomoto Y, Shimojo N, Kawano S, Mizutani T
    • Journal Title

      Am J Emerg Med

      Volume: 36 Issue: 2 Pages: 344.e5-344.e7

    • DOI

      10.1016/j.ajem.2017.11.029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819, KAKENHI-PROJECT-17K19787, KAKENHI-PROJECT-17K17623
  • [Journal Article] Combination Therapy with Peritoneal Dialysis and Hemodialysis from the Initiation of Renal Replacement Therapy Preserves Residual Renal Function and Serum Albumin.2017

    • Author(s)
      A Ueda, K Nagai, A Hirayama, C Saito, K Yamagata
    • Journal Title

      Advances in peritoneal dialysis

      Volume: 33 Pages: 74-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Journal Article] Neurovascular Unit Protection From Cerebral Ischemia-Reperfusion Injury by Radical-Containing Nanoparticles in Mice2017

    • Author(s)
      Hosoo H, Marushima A, Nagasaki Y, Hirayama A, Ito H, Puentes S, Mujagic A, Tsurushima H, Tsuruta W, Suzuki K, Matsui H, Matsumaru Y, Yamamoto T, Matsumura
    • Journal Title

      Stroke

      Volume: 48 Issue: 8 Pages: 2238-2247

    • DOI

      10.1161/strokeaha.116.016356

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10819, KAKENHI-PROJECT-25220203, KAKENHI-PROJECT-16K15628
  • [Journal Article] 理学療法士による運動とその効果.CKD患者のサルコペニア・フレイル2016

    • Author(s)
      三浦美佐,平山暁
    • Journal Title

      腎と透析

      Volume: 80.5 Pages: 745-750

    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Journal Article] 2015 国際学会報告2016

    • Author(s)
      三浦美佐,平山 暁,大和田滋,前波輝彦,小川佳子,伊藤 修,上月正博
    • Journal Title

      筑波技術大学テクノレポート

      Volume: 23(2) Pages: 50-53

    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Journal Article] Effects of a renal rehabilitation exercise program in patients with CKD: Controlled trial.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Ito O, Kohzuki M.
    • Journal Title

      F1000 Research

      Volume: 1 Pages: 421-421

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Journal Article] Design and use of silica-containing redox nanoparticles, siRNP for high-performance peritoneal dialysis2014

    • Author(s)
      Yukio Nagasaki, Tatsuya Yaguchi, Takuma Matsumura, Toru Yoshitomi, Yutaka Ikeda, Atsushi Ueda, and Aki Hirayama
    • Journal Title

      Biomaterials Science

      Volume: 2 Issue: 4 Pages: 522-529

    • DOI

      10.1039/c3bm60236b

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J06119, KAKENHI-PROJECT-24591224, KAKENHI-PUBLICLY-25107707, KAKENHI-PROJECT-25220203
  • [Journal Article] ROS-scavenging Nanomedicine for Treatment of Oxidative Stress Injuries2014

    • Author(s)
      Toru Yoshitomi, Yukio Nagasaki
    • Journal Title

      Advanced Healthcare Materials

      Volume: 3 Issue: 8 Pages: 1149-1161

    • DOI

      10.1002/adhm.201300576

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J06119, KAKENHI-PROJECT-24591224, KAKENHI-PROJECT-25220203
  • [Journal Article] Redox-active injectable gel using thermo-responsive nanoscale polyion complex flower micelle for noninvasive treatment of local inflammation.2013

    • Author(s)
      Pua ML, Yoshitomi T, Chonpathompikunlert P, Hirayama A, Nagasaki Y
    • Journal Title

      J Control Release

      Volume: 172 Issue: 3 Pages: 914-920

    • DOI

      10.1016/j.jconrel.2013.10.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591224, KAKENHI-PROJECT-24659920, KAKENHI-PUBLICLY-25107707, KAKENHI-PROJECT-25220203
  • [Journal Article] Newly Synthesized Radical-containing Nanoparticles (RNP)Enhance Neuroprotection after Cerebral Ischemia-reperfusion Injury2011

    • Author(s)
      Aiki Marushima, Hideo Tsurusima, Toru Yoshitomi, Kazuko Toh, Aki Hirayama, Yukio Nagasaki, Akira Matumura
    • Journal Title

      Neurosurgery

      Volume: 68 Issue: 5 Pages: 1418-1426

    • DOI

      10.1227/neu.0b013e31820c02d9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21240050, KAKENHI-PROJECT-21591018, KAKENHI-PROJECT-22800004
  • [Journal Article] The ROS scavenging and renal protective effects of pH-responsive nitroxide radical-containing nanoparticles2011

    • Author(s)
      Toru Yoshitomi, Aki Hirayama, Yukio Nagasaki
    • Journal Title

      Biomaterials

      Volume: 32 Issue: 31 Pages: 8021-8028

    • DOI

      10.1016/j.biomaterials.2011.07.014

    • NAID

      120007137437

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21240050, KAKENHI-PROJECT-21591018, KAKENHI-PROJECT-22659008
  • [Journal Article] Spherical carbon adsorbent (AST-120) protects deterioration of renal function in chronic kidney disease rats through inhibition of reactive oxygen species production from mitochondria and reduction of serum lipid peroxidation2010

    • Author(s)
      Owada S, Maeba T, Sugano Y, Hirayama A, Ueda A, Nagase S, Goto S, Nishijima F, Bannai K, Yamato H
    • Journal Title

      Nephron Exp Nephrol

      Volume: 115(4)

    • Data Source
      KAKENHI-PROJECT-21591018
  • [Journal Article] Development of a pH-Sensitive Reno-Protective Nano-Particle for Relief of Ischemia-Reperfusion Acute Kidney Injury.2010

    • Author(s)
      Hirayama A
    • Journal Title

      Journal of American Society of Nephrology

      Volume: 21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Journal Article] NADPH oxidase isoforms and anti-hypertensive effects of atorvastatin demonstrated in two animal models.2009

    • Author(s)
      Cui W, Matsuno K, Iwata K, Ibi M, Katsuyama M, Kakehi T, Sasaki M, Ikami K, Zhu K, Yabe-Nishimura C.
    • Journal Title

      J Pharmacol Sci 111

      Pages: 260-268

    • NAID

      10026154161

    • Data Source
      KAKENHI-PROJECT-20390071
  • [Journal Article] pH-Sensitive Radical.Containing-Nanoparticle (RNP) for theL-Band-EPR Imaging of Low pH Circumstances2009

    • Author(s)
      Yoshitomi T, Suzuki R, Mamiya T, Matsui H, Hirayama A, Nagasaki Y.
    • Journal Title

      Bioconjugate Chem

      Volume: 20 Pages: 1792-1798

    • Data Source
      KAKENHI-PROJECT-21591018
  • [Journal Article] In vivo imaging of renal redox status during azelnidpine treatments2008

    • Author(s)
      Hirayama A.
    • Journal Title

      Hypertension Research (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Journal Article] In vivo imaging of renal redox status during azelnidpine treatments2008

    • Author(s)
      Hirayama A.
    • Journal Title

      Hypertension Research (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Journal Article] The AP-1 site is essential for the promoter activity of NOX1/NADPH oxidase, a vascular superoxide-producing enzyme : Possible involvement of the ERK1/2-JunB pathway.2008

    • Author(s)
      Cevik MO, Katsuyama M, Kanda S, Kaneko T, Iwata K, Ibi M, Matsuno K, Kakehi T, Cui W, Sasaki M, Yabe-Nishimura C.
    • Journal Title

      Biochem Biophys Res Commun 374

      Pages: 351-355

    • Data Source
      KAKENHI-PROJECT-20390071
  • [Journal Article] Electron paramagnetic resonance imaging of oxidative stress in renal disease.2006

    • Author(s)
      Hirayama A
    • Journal Title

      Nephron Clinical Practice 103

    • Data Source
      KAKENHI-PROJECT-18590878
  • [Journal Article] Renal redox imaging and in vivo analysis during antihypertensive treatments.2006

    • Author(s)
      Hirayama A
    • Journal Title

      Nephrology Dialysis Transplantation 21・Suppl.4

      Pages: 41-42

    • Data Source
      KAKENHI-PROJECT-18590878
  • [Journal Article] In vivo imaging of oxidative stress in ischemia-reperfusion renal injury using electron paramagnetic resonance.2005

    • Author(s)
      Hirayama A. et al.
    • Journal Title

      American Journal of Physiology Renal Physiology 208・3

    • Data Source
      KAKENHI-PROJECT-15790427
  • [Journal Article] Electron paramagnetic resonance imaging of nitric oxide organ distribution in lipopolysuccaride treated mice2003

    • Author(s)
      Hirayama A. et al.
    • Journal Title

      Molecular and Cellular Biochemistry 244・1

      Pages: 63-67

    • Data Source
      KAKENHI-PROJECT-15790427
  • [Journal Article] Oxidative stress during leukocyte absorption apheresis2003

    • Author(s)
      Hirayama A. et al.
    • Journal Title

      Journal of Clinical Apheresis 18・2

      Pages: 61-66

    • Data Source
      KAKENHI-PROJECT-15790427
  • [Journal Article] EPR imaging of reducing activity in Nrf2 transcriptional factor deficient mice.2003

    • Author(s)
      Hirayama A. et al.
    • Journal Title

      Free Radical Biology & Medicine 34・10

      Pages: 1236-1242

    • Data Source
      KAKENHI-PROJECT-15790427
  • [Patent] 自閉症スペクトラム障害の判定方法、自閉症スペクトラム障害の判定用キット及び測定データ取得方法2019

    • Inventor(s)
      平山暁、松﨑秀夫
    • Industrial Property Rights Holder
      平山暁、松﨑秀夫
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Acquisition Date
      2021
    • Data Source
      KAKENHI-PROJECT-19K21754
  • [Patent] 高分子環状ニトロキシドラジカル化合物とシリカの有機―無機ハイブリッド複合体2013

    • Inventor(s)
      長崎幸夫,吉冨 徹,平山 暁他
    • Industrial Property Rights Holder
      長崎幸夫,池田 豊,吉冨 徹,植田敦志,平山 暁,他
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-02-06
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Patent] 高分子環状ニトロキシドラジカル化合物とシリカの有機.無機ハイブリッド複合体2012

    • Inventor(s)
      長崎幸夫,吉冨徹,池田豊,植田敦志,平山暁,矢口達也,山下真代
    • Industrial Property Rights Holder
      国立大学法人筑波大学,国立大学法人筑波技術大学
    • Industrial Property Number
      2012-024460
    • Filing Date
      2012-02-07
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Patent] 高分子環状ニトロキシドラジカル化合物とシリカの有機-無機ハイブリッド複合体2012

    • Inventor(s)
      長崎幸夫, 吉冨徹, 池田豊, 植田敦志, 平山暁, 矢口達也, 山下真代
    • Industrial Property Rights Holder
      長崎幸夫, 吉冨徹, 池田豊, 植田敦志, 平山暁, 矢口達也, 山下真代および国立大学法人筑波大学国立大学法人筑波技術大学
    • Industrial Property Number
      2012-024460
    • Filing Date
      2012-02-07
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Patent] Polymerized cyclic nitro-xide radical compound, and use thereof2010

    • Inventor(s)
      NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSUMUR A, Akira. SUZUKI, Kensuke. TSURUSHIM A, Hideo. MARUSHIMA, Aiki. TOH, Kazuko MIYAMOTO, Daisuke
    • Industrial Property Rights Holder
      NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSUMUR A, Akira. SUZUKI, Kensuke. TSURUSHIM A, Hideo. MARUSHIMA, Aiki. TOH, Kazuko MIYAMOTO, DaisukeおよびUniversity of Tsukuba
    • Filing Date
      2010-11-02
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Patent] Polymerized cyclic nitro-xide radical compound, and use thereof2010

    • Inventor(s)
      NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSUMUR A, Akira. SUZUKI, Kensuke. TSURUSHIM A, Hideo. MARUSHIMA, Aiki. TOH, Kazuko MIYAMOTO, Daisuke
    • Industrial Property Rights Holder
      NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSUMUR A, Akira. SUZUKI, Kensuke. TSURUSHIM A, Hideo. MARUSHIMA, Aiki. TOH, Kazuko MIYAMOTO, DaisukeおよびUniversity of Tsukuba
    • Filing Date
      2010-11-02
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Patent] Polymerized cyclic nitroxide radical compound, and use thereof2009

    • Inventor(s)
      NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSU-MURA, ra. SUZUKI, Kensuke. TSURUSHI-MA, Hideo. MARUSHI-MA, AiKi. TOH, Kazuko. MIYAMOTO, Daisuke
    • Industrial Property Rights Holder
      NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSU-MURA, ra. SUZUKI, Kensuke. TSURUSHI-MA, Hideo. MARUSHI-MA, AiKi. TOH, Kazuko. MIYAMOTO, Daisukeおよび University of Tsukuba
    • Filing Date
      2009-05-11
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Patent] Polymerized cyclic nitroxide radical compound, and use thereof2009

    • Inventor(s)
      NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSUMURA, Akira. SUZUKI, Kensuke. TSURUSHIMA, Hideo. MARUSHIMA, Aiki. TOH, Kazuko. MIYAMOTO, Daisuke
    • Industrial Property Rights Holder
      同左およびUniversity of Tsukuba
    • Filing Date
      2009-05-11
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Patent] Polymerized cyclic nitroxide radical compound, and use thereof2009

    • Inventor(s)
      NAGASAKI Yukio, YOSHITOMI Toru, MATSUI Hirofumi, HIRAYAMA Aki,MAMIYA Takashi, MATSUMURA Akira, SUZUKI Kensuke, TSURUSHIMA Hideo,MARUSHIMA Aiki, TOH Kazuko, MIYAMOTO Daisuke
    • Industrial Property Rights Holder
      NAGASAKI Yukio, YOSHITOMI Toru, MATSUI Hirofumi, HIRAYAMA Aki, MAMIYA Takashi, MATSUMURA Akira, SUZUKI Kensuke, TSURUSHIMA Hideo, MARUSHIMA Aiki, TOH Kazuko, MIYAMOTO Daisuke, University of Tsukuba
    • Filing Date
      2009-05-11
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Regional cortical hypoperfusion and atrophy correlated with dopaminergic loss in Parkinson's disease2022

    • Author(s)
      Ikawa M, Kitazaki Y, Yamaguchi T, Enomoto S, Shirafuji N, Yamamura O, Tsujikawa T, Okazawa H, Kimura H, Nakamoto Y, Hamano T
    • Organizer
      第63回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-20K07900
  • [Presentation] 虚血性脳卒中に対する神経保護薬の研究開発と事業化構想2022

    • Author(s)
      丸島愛樹,長崎幸夫,Arnela Mujagic,渡邉真哉、細尾久幸,秋本大輔、平山暁,石川栄一,松丸祐司
    • Organizer
      第65回日本脳循環代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03787
  • [Presentation] ナノメディシンによる虚血性脳卒中に対する神経保護療法の開発2022

    • Author(s)
      丸島愛樹,長崎幸夫,Arnela Mujagic,平田浩二、渡邉真哉、松村英明、細尾久幸,平山暁,石川栄一,松丸祐司
    • Organizer
      第47回日本脳卒中学会
    • Data Source
      KAKENHI-PROJECT-20H03787
  • [Presentation] 重症虚血性脳卒中のレドックス反応を制御する神経保護薬の開発2022

    • Author(s)
      丸島愛樹,長崎幸夫,Arnela Mujagic,渡邉真哉、細尾久幸,平山暁,石川栄一,松丸祐司
    • Organizer
      第75回日本酸化ストレス学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03787
  • [Presentation] Antioxidant Nanomedicine with Cytoplasmic Distribution in Neuronal Cells Shows Superior Neurovascular Protection Properties for Ischemic Stroke in Mice2021

    • Author(s)
      Arnela Mujagic, Aiki Marushima, Yukio Nagasaki, Hisayuki Hosoo, Aki Hirayama, Sandra Puentes, Toshihide Takahashi Hideo Tsurushima, Kensuke Suzuki, Hirofumi Matsui, Eiichi Ishikawa, Yuji Matsumaru, Akira Matsumura.
    • Organizer
      第34回日本酸化ストレス学会関東支部
    • Data Source
      KAKENHI-PROJECT-20H03787
  • [Presentation] 映像化解析による補腎剤と駆お血剤の血流改善効果の差異の描出-牛車腎気丸と桂枝茯苓丸 における検討-2021

    • Author(s)
      平山 暁、富田 勉、長野由美子、青柳 一正
    • Organizer
      第71回日本東洋医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Presentation] Kamishoyosan ameliorates antioxidative profiles via an oxidative stress-related hormesis pathway.2021

    • Author(s)
      Hirayama A, Nagano Y, Tomita T
    • Organizer
      Japan-Korea Academical Symposium, The 71st Annual Meeting of the Japan Society for Oriental Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Presentation] レドックスナノ粒子による新たな神経保護療法の実用化2021

    • Author(s)
      丸島愛樹、長崎幸夫、Arnela Mujagic、細尾久幸、平山暁、松井裕史、秋本大輔、渡邉真哉、石川栄一、松丸祐司、松村明
    • Organizer
      第74回日本酸化ストレス学会
    • Data Source
      KAKENHI-PROJECT-20H03787
  • [Presentation] レドックスナノ粒子による虚血性脳卒中に対する脳保護療法の開発2020

    • Author(s)
      丸島愛樹、長崎幸夫、Arnela Mujagic、細尾久幸、平山暁、松井裕史、Sandra Puentes、鈴木謙介、石川栄一、松丸祐司、松村明
    • Organizer
      第73回日本酸化ストレス学会、2020.10.6,米子
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03787
  • [Presentation] VLDL-specific increases of fatty acids in autism spectrum disorders correlate with social interaction.2020

    • Author(s)
      Matsuzaki H, Iwata K, Usui N.
    • Organizer
      第63回日本神経化学会、2020年9月10日、WEB開催
    • Data Source
      KAKENHI-PROJECT-19K21754
  • [Presentation] 脳梗塞急性期血栓回収療法におけるレドックスナノ粒子による脳保護療法の開発2020

    • Author(s)
      丸島愛樹,長崎幸夫,Arnela Mujagic,秋本大輔,松村英明,渡邉真哉、平田浩二,後藤正幸, Sandra Puentes,細尾久幸,平山暁,鈴木謙介,石川栄一,松村明,松丸祐司,
    • Organizer
      第63回脳循環代謝学会2020.11.13 横浜, 学会認定シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03787
  • [Presentation] Gut-Kidney Cross-Talk, Uremic Toxin, Oxidative Stress.2019

    • Author(s)
      Hirayama A.
    • Organizer
      The 9th biennial meeting for the Society for Free Radical Research Asia (SFRR Asia 2019)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Presentation] 抗酸化ナノメディシン(RNP)による脳虚血再灌流障害に対する脳保護療法2019

    • Author(s)
      丸島 愛樹、長崎 幸夫、Arnela Mujagic、細尾 久幸、平山 暁、松井 裕史、Sandra Puentes、鈴木 謙介、滝川 知司、石川 栄一、井上 貴昭、松丸 祐司、松村 明
    • Organizer
      第72回日本酸化ストレス学会
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Presentation] 脳梗塞急性期血栓回収療法における抗酸化ナノメディシン(RNP)による脳保護療法の開発2019

    • Author(s)
      丸島愛樹,長崎幸夫,Arnela Mujagic,松村英明,平田浩二,秋本大輔,Sandra Puentes,細尾久幸,平山暁,鈴木謙介,滝川知司,石川栄一,松丸祐司,松村明
    • Organizer
      第62回脳循環代謝学会
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Presentation] Connotation of weak antioxidants/pro-oxidants in the traditional prescriptions of Kampo, Japanese traditional medicine.2019

    • Author(s)
      Hirayama A.
    • Organizer
      The 9th Joint Meeting of the Society of Free Radical Research Australasia and Japan
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Presentation] 脳梗塞急性期再開通療法における新たな脳保護療法のトランスレーショナルリサーチ2019

    • Author(s)
      丸島愛樹、長崎幸夫、細尾久幸、Mei Ting、Arnela Mujagic、松村英明、Sandra Puentes、平山暁、鈴木謙介、滝川知司、石川栄一、井上貴昭、松丸祐司、松村明
    • Organizer
      第78回日本脳神経学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Presentation] Measurement of Multiple Radical Scavenging Activity as a diagnostic method for autism spectrum disorder in children.2019

    • Author(s)
      Matsuzaki H, Hirayama A.
    • Organizer
      The 16th ASMRM and The 19th J-mit
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K21754
  • [Presentation] 生体微小撮影による,各種駆お血剤の微小循環における標的血管と血流増加機序の映像化解析2019

    • Author(s)
      平山 暁,富田 勉,青柳一正
    • Organizer
      第70回日本東洋医学会総会
    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Presentation] 脳梗塞急性期再開通療法における環境応答性ナノ粒子化活性酸素消去剤(RNP)による脳保護療法の開発2018

    • Author(s)
      丸島愛樹、細尾久幸、長崎幸夫、Mujagic A、Puentes S、平山 暁、鈴木謙介、滝川知司、早川幹人、伊藤嘉朗、鶴嶋英夫、松井裕史、石川栄一、井上貴昭、松丸祐司、松村 明
    • Organizer
      第43回日本脳卒中学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Presentation] Neurovascular Unit Protection Using Nitroxide Radicals-containing Nanoparticles (TEMPO-RNP) for Cerebral Ischemia-reperfusion Injury in Mice2018

    • Author(s)
      Hisayuki Hosoo, Aiki Marushima, Yukio Nagasaki, Aki Hirayama, Hiromu Ito, Sandra Puentes, Arnela Mujagic, Hideo Tsurushima, Wataro, Kensuke Suzuki; Hirofumi Matsui, Yuji Matsumaru, Tetsuya Yamamoto, Akira Matsumura
    • Organizer
      International stroke conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Presentation] Long Term Renal Rehabilitation Induces a Significant Shift in Serum Antioxidative Profile.2018

    • Author(s)
      Hirayama A, Ueda A, Miura M, Yasuda G, Nishida A, Hirayama Y, Kohzuki M, Oowada S.
    • Organizer
      Annual Dialysis Conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] ライブイメージング技術の応用による駆お血剤薬理効果定量解析の試み2018

    • Author(s)
      平山 暁,富田 勉,青柳 一正.
    • Organizer
      第75回日本東洋医学会関東甲信越支部学術総会
    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Presentation] ナノ粒子化活性酸素消去剤(RNP)による神経保護療法の実用化を目指した研究開発2018

    • Author(s)
      丸島愛樹、長崎幸夫、Mujagic A、高橋利英、渡部大輔、松村英明、Ting M、Puentes S、細尾久幸、平山暁、鈴木謙介、滝川知司、石川栄一、井上貴昭、松丸祐司、松村 明
    • Organizer
      日本脳神経外科学会第77回学術総会
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Presentation] 脳梗塞急性期血栓回収療法におけるナノ粒子化活性酸素消去剤(RNP)による脳保護療法の開発2018

    • Author(s)
      丸島愛樹、長崎幸夫、Mujagic A、高橋利英、渡部大輔、松村英明、Ting M、Puentes S、細尾久幸、平山 暁、鈴木謙介、滝川知司、石川栄一、井上貴昭、松丸祐司、松村 明
    • Organizer
      第61回日本脳循環代謝学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Presentation] 抗酸化ナノメディシン(RNP)による急性脳主幹動脈閉塞に対する脳保護療法の開発2018

    • Author(s)
      丸島愛樹、長崎幸夫、細尾久幸、Mujagic A、松村英明、渡部大輔、Puentes S、平山 暁、松井裕史、鈴木謙介、滝川知司、早川幹人、佐藤允之、伊藤嘉朗、石川栄一、井上貴昭、松丸祐司、松村 明
    • Organizer
      第33回日本酸化ストレス学会関東支部会
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Presentation] 毛細血管・赤血球の異常を再現したお血類似病態のライブイメージングと,駆お血剤による血流動態及び NO 産生効果の動画解析2018

    • Author(s)
      平山 暁,富田 勉,青柳 一正.
    • Organizer
      第69回日本東洋医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Presentation] ミニシンポジウム 「臨床現場でのESR応用」2018

    • Author(s)
      平山 暁
    • Organizer
      第57回電子スピンサイエンス学会(SEST2018)
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Presentation] Redox nano-particle for peritoneal dialysis solution2017

    • Author(s)
      Hirayama A, Nagasaki Y, Yaguchi T, Matsumura T, Yoshitomi T, Ikeda Y, Ueda A.
    • Organizer
      Annual Dialysis Conference 2017
    • Place of Presentation
      Long Beach Convention Center, Long Beach, CA, USA
    • Year and Date
      2017-03-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] 活性酸素消去剤封入ナノ粒子(RNP)による脳虚血再灌流障害に対するNeurovascular unit保護効果2017

    • Author(s)
      丸島愛樹、細尾久幸、長崎幸夫、平山暁、Sandra Puentes、Arnela Mujagic 、伊藤紘、鶴嶋英夫、鶴田和太郎、鈴木謙介、松井裕史、松丸祐司、山本哲哉、松村明
    • Organizer
      第60回脳循環代謝学会
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Presentation] Exercise program for chronic kidney disease improves pathophysiological condition with a shift of oxidative stress.2017

    • Author(s)
      Hirayama A, Miura M, Yasuda G, Nagano Y, Matsui H, Hirayama Y, Ueda A, Aoyagi K, Kohzuki M, Oowada S.
    • Organizer
      The Society for Redox Biology and Medicine's 24th Annual Meeting (SfRBM 2017)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] 性腎臓病進行抑制のため自宅での電気刺激療法を試みた1症例2017

    • Author(s)
      三浦美佐,斎藤知栄,平山暁,伊藤修,上月正博,山縣邦弘
    • Organizer
      日本腎臓リハビリテーション学会
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] OXIDATIVE STRESS DURING RENAL REHABILITATION2017

    • Author(s)
      Hirayama A, Miura M, Hirayama Y, Nagano Y, Yasuda G, Ueda A, Matsui H, Aoyagi K, Kozuki M, Oowada S.
    • Organizer
      World Conference of Nephrology 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] Effects of a renal rehabilitation exercise program in patients with end-stage renal disease: study protocol for a multicenter controlled trial2016

    • Author(s)
      M. Miura, M. Kohzuki, S. Oowada, Y. Hirayama, O. Ito,A. Hirayama.
    • Organizer
      10th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Year and Date
      2016-05-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] 血液透析中の運動療法または下肢電気刺激は身体機能を改善する:多施設共同治験2016

    • Author(s)
      [3]平山真喜子,吉澤亮,戀塚ゆかり,鈴木志穂,鈴木綾子, 三浦美佐,大和田滋,前波輝彦
    • Organizer
      第 6 回日本腎臓リハビリテーション学会
    • Place of Presentation
      大阪国際会議場, 大阪府
    • Year and Date
      2016-06-09
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] Effects of a renal rehabilitation exercise program in patients with end stage renal disease: study protocol for a multi-center controlled trial.2016

    • Author(s)
      Miura M, Oowada S, Hirayama Y, Hirayama A, Ito O, Kohzuki M.
    • Organizer
      10th Interantional Soceity of Physical and Rehabilitation Medicine World Congress.
    • Place of Presentation
      Kuala Lumpur Convention Centre
    • Year and Date
      2016-05-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] Comparison of electric bike exercise to conventional bicycle training during hemodialysis sessions on physical function in patients with end stage renal disease2016

    • Author(s)
      M Miura , R Yoshizawa, S Oowada, A Hirayama, O Ito, Y Hirayama, M Kohzuki, T Maeba
    • Organizer
      American Society of Nephrology(Kidney Week 2016)
    • Place of Presentation
      Chicago, America
    • Year and Date
      2016-11-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] 透析中の運動療法での高齢透析患者の酸化ストレス消去活性への影響2016

    • Author(s)
      三浦美佐,平山暁, 大和田滋,平山陽,伊藤修,上月正博
    • Organizer
      第 28 回腎とフリーラジカル研究会
    • Place of Presentation
      つくば国際会議場, 茨城県
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] Advantages of nutrition counseling in CKD patients by a professional dietician on the physical or psychological state.2016

    • Author(s)
      Ueda A, Hirayama A, Yamagata K.
    • Organizer
      ASN Kidney Week 2016 Annual Meeting of the American Society of Nephrlogy
    • Place of Presentation
      McCormic Place, Chicago, IL., USA
    • Year and Date
      2016-11-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] Effects of Aerobic Training and Electrical Stimulation to Skeletal Muscles during Hemodialysis for Patients with End-Stage Renal Disease.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Ito O, Kohzuki M.
    • Organizer
      9th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2015-06-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] Multicenter trial of aerobic exercise in maintenance hemodialysis patients : Clinical and biochemical effects.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Ito O, Hirayama Y, Kohzuki M.
    • Organizer
      2015 Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2015-11-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] Effects of a renal rehabilitation exercise program in patients with CKD: Controlled trial.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Ito O, Kohzuki M.
    • Organizer
      52th ERA-EDTA
    • Place of Presentation
      London, England
    • Year and Date
      2015-05-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] 血液透析患者の酸化ストレスは抗酸化力の減弱ではなく変質による2015

    • Author(s)
      平山 暁,植田敦志,大和田滋,永瀬宗重,青柳一正
    • Organizer
      第60回日本透析医学会学術集会
    • Place of Presentation
      みなとみらい,横浜市
    • Year and Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] 血液透析中の運動療法や下肢電気刺激は身体機能を改善する2015

    • Author(s)
      三浦美佐,平山 暁,大和田滋,伊藤 修,上月正博
    • Organizer
      第60回日本透析医学会学術集会
    • Place of Presentation
      みなとみらい,横浜市
    • Year and Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] Oxidative Stress of Chronic Kidney Disease (CKD) Patients Changes in Quality, Not in Quantity.2015

    • Author(s)
      Hirayama A, Oowada S, Ueda A, Aoyagi K.
    • Organizer
      7th Biennial Meeting of Society for Free Radical Research-Asia.
    • Place of Presentation
      Chiang-Mai, Thailand
    • Year and Date
      2015-11-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] Multicenter trial of aerobic exercise in maintenance hemodialysis patients: Clinical and biochemical effects.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Hirayama Y, Ito O, Kohzuki M.
    • Organizer
      2015 ASN
    • Place of Presentation
      San Diego, America
    • Year and Date
      2015-11-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] Design of Nanoparticle therapeutics for ischemia reperfusion injuries.2014

    • Author(s)
      Nagasaki Y, Yoshitomi T, Toh K, Marushima A, Tsurushima H, Suzuki K, Matsumura A, Hirayama A, Sanada S, Yoshida A, Kitakaze M.
    • Organizer
      2nd International Meeting on Ischemia Reperfusion Injury in Transplantation.
    • Place of Presentation
      Poitiers (France)
    • Year and Date
      2014-04-25
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] Preparation and evaluation of silica-containing redox nanoparticle for peritoneal dialysis which aimed at the medical treatment of chronic renal failure2013

    • Author(s)
      Matsumura T, Yaguchi T, Amraon Md, Ikeda Y, Yoshitomi T, Hirayama A, Ueda A, Nagasaki Y
    • Organizer
      Tsukuba International Conference on Materials Science
    • Place of Presentation
      Tsukuba International Congress Center, Tsukuba
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] Uremic toxin indoxyl sulfate induce mitochondrial superoxide leakage.2012

    • Author(s)
      Hirayama A
    • Organizer
      19th Annual Meeting of the Society for Free Radical Biology and Medicine
    • Place of Presentation
      San Diego, CA, USA
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] Novel redox nanotherapy fof renal ischemia reperfusion injury2011

    • Author(s)
      Nagasaki Y, Yoshitomi T, Hirayama A
    • Organizer
      XLVIII ERA-EDTA Congress
    • Place of Presentation
      Prague, Czech Rep
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Application of ESR and Spin Technologies for the Control of Kidney Diseases2011

    • Author(s)
      Hirayama A, Ueda A, Nagase S, Aoyagi K, Owada S
    • Organizer
      International Workshop"Advanced ESR Studies for New Frontiers in Biofunctional Spin Science and Technology"(AEBST 2011)
    • Place of Presentation
      Kobe
    • Year and Date
      2011-11-13
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] 急性腎障害に対するナノ粒子治療の開発シンポジウムJapan Kidney Week 20112011

    • Author(s)
      平山暁,吉富徹,長崎幸夫
    • Organizer
      第55回(社)日本透析医学会学術集会・総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Novel redox nanotherapy fof renal ischemia reperfusion injury2011

    • Author(s)
      Nagasaki Y.
    • Organizer
      XLVIII ERA-EDTA Congress
    • Place of Presentation
      Prague
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Indoxyl sulfate and guanidino succinic acid directly induce mitochondrial superoxide production2011

    • Author(s)
      Hirayama A.
    • Organizer
      XLVIII ERA-EDTA Congress
    • Place of Presentation
      Prague
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] レドックス反応性ナノ粒子による腎虚血再灌流障害の治療第2011

    • Author(s)
      吉冨徹,平山暁,長崎幸夫
    • Organizer
      64回日本酸化ストレス学会学術集会
    • Place of Presentation
      北海道,ルスツ
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] pH応答性TEMPO含有ナノ粒子のマウス急性腎不全モデルに対する保護効果2010

    • Author(s)
      平山暁
    • Organizer
      第22回腎とフリーラジカル研究会
    • Place of Presentation
      町村会館(東京)
    • Year and Date
      2010-10-16
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Design of nitroxyl radicals containing nanoparticle for MR imaging of tumor2010

    • Author(s)
      Yoshitomi T, Matsumoto S, Krishna MC, Matsumoto K, Anzai K, Matsui H, Hirayama A, Nagasaki Y
    • Organizer
      The 37th Annual Meeting and Exposition of the Controlled Release Society
    • Place of Presentation
      Oregon Convention Center, Portland, Oregon, USA.
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Design of pH-sensitive polymeric micelle possessing reduced forms of TEMPO for imaging of ROS2010

    • Author(s)
      Yoshitomi T, Mamiya T, Matsui H, Hirayama A, Nagasaki Y
    • Organizer
      Young Investigator's Award winning presentation
    • Place of Presentation
      Oxygen Club California World Congress, Santa Barbara, CA, USA.
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] 反応性イメージングを目指したニトロキシルラジカル含有ナノ粒子の設計と評価2010

    • Author(s)
      吉冨徹、間宮孝、松井裕史、平山暁、長崎幸夫
    • Organizer
      第26回日本DDS学会学術集会
    • Place of Presentation
      大阪国際交流センター
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Novel Nanosphere Theranostic for Anti-Oxidative Stress2010

    • Author(s)
      Nagasaki Y
    • Organizer
      THE 1st INTERNATIONAL CONFERENCE FOR GREEN TECHNOLOGIES
    • Place of Presentation
      Ajou University, Suwon, Korea
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Development of a pH-Sensitive Reno-Protective Nano-Particle for Relief of Ischemia-Reperfusion Acute Kidney Injury2010

    • Author(s)
      Hirayama A, Yoshitomi T, Owada S, Ueda A, Matsui H, Aoyagi K, Nagasaki Y
    • Organizer
      43rd Annual meeting of the American Society of Nephrology (Renal Week 2010)
    • Place of Presentation
      Denver (abstract in J Am Soc Nephrol)
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Development of a pH-Sensitive Reno-Protective Nano-Particle for Relief of Ischemia-Reperfusion Acute Kidney Injury.2010

    • Author(s)
      Hirayama A
    • Organizer
      43rd Annual meeting of the American Society of Nenhroloev (Renal Week 2010)
    • Place of Presentation
      Colorado Convention Center (Denver, CO)
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Design of redox imaging nanoprobe using nitroxyl radical containing nanoparticle2010

    • Author(s)
      Yoshitomi T, Mamiya T, Matsui H, Hirayama A ,Nagasaki Y
    • Organizer
      SFRBM 2010-17th Annual Meeting of the Society for Free Radical Biology and Medicine
    • Place of Presentation
      Orlando, Florida
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Development of TEMPOL-Containing Nano-Particle for Continuous Superoxide Scavenging and Antihypertension.2009

    • Author(s)
      Hirayama A, Yoshitomi T, Ueda A, Matsui H, Owada S, Aoyagi K, Nagasaki Y
    • Organizer
      42nd Annual meeting of the American Society of Nephrology (Renal Week 2009)
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Healing of Oxidative Stress in Brain on the Occasion of Cerebral Ischemia-Reperfusion.2009

    • Author(s)
      Yoshitomi T, Toh K, Marushima A, Suzuki K, Tsurushima H, Hirayama A, Matsumura A, Nagasaki Y
    • Organizer
      2009 Gordon Research Conference on Biomaterials: Biocompatibility and Tissue Engineering
    • Place of Presentation
      Plymouth (USA)
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] 安定した抗酸化・降圧効果を発揮するナノ粒子化TEMPOの開発2009

    • Author(s)
      平山暁,吉冨徹,植田敦志,青柳一正,長崎幸夫
    • Organizer
      第52回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-03
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] ラジカル含有ナノ粒子を用いた脳虚血-再潅流モデルラットにおける脳梗塞の抑制2009

    • Author(s)
      藤加珠子、吉冨徹、丸島愛樹、鈴木謙介、鶴嶋英夫、平山暁、松村明、長崎幸夫
    • Organizer
      第62回日本酸化ストレス学会学術集会
    • Place of Presentation
      福岡ポスターアワード(優秀演題賞)受賞演題)
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] 生体内ROSの可視化を目指したEPRナノプローブの創製2009

    • Author(s)
      吉冨徹、間宮孝、松井裕史、平山暁、長崎幸夫
    • Organizer
      第62回日本酸化ストレス学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2009-06-11
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Development of TEMPOL-Containing Nano-Particle for Continuous Superoxide Scavenging and Antihypertension2009

    • Author(s)
      Hirayama A
    • Organizer
      42nd Annual meeting of the American Society of Nephrology(Renal Week 2009)
    • Place of Presentation
      San Diego, California, United States of America
    • Year and Date
      2009-10-30
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] TEMPO含有ナノ粒子の開発と生体内動態2009

    • Author(s)
      吉冨徹、平山暁、間宮孝、松井裕史、長崎幸夫
    • Organizer
      第48回電子スピンサイエンス学会年会(SEST2009)
    • Place of Presentation
      神戸
    • Year and Date
      2009-11-12
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Stable Radical-containing Nanoparticles for Anti-oxydative Stress Disease2009

    • Author(s)
      Nagasaki Y
    • Organizer
      FBPS2009
    • Place of Presentation
      Mishima
    • Year and Date
      2009-05-20
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] 血液透析の抗酸化的側面 ワークショップ「透析患者の酸化ストレスUp to date」2007

    • Author(s)
      平山 暁
    • Organizer
      第52回日本透析医学会総会・学術集会
    • Place of Presentation
      大阪
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Presentation] Imbalance of Mitochondrial Superoxide and Intracellular Nitric Oxide in the Hyperproteinuric Phase of Puromycin Nephrosis2007

    • Author(s)
      Hirayama A.
    • Organizer
      40th annual meeting of the American Society of Nephrology
    • Place of Presentation
      San Francisco, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Presentation] Ketsueki Touseki no Kousanka-teki Sokumen (Antioxidataive Effects of Hemodialysis), Workshop: Oxidative Stress in Dialysis Patients, UP to DATE2007

    • Author(s)
      Hirayama A.
    • Organizer
      52nd Annual Meeting of Japanese Society for Dialysis Therapy
    • Place of Presentation
      Osaka
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Presentation] In vivo EPR analysis and imaging of antihypertensive drugs on renal reducing activity2007

    • Author(s)
      Hirayama A.
    • Organizer
      EPR 2007: A Joint Conference of 12th In Vivo EPR Spectroscopy and Imaging 9th International EPR Spin Trapping/ Spin Labeling
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2007-04-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Presentation] Imbalance of Mitochondrial Superoxide and Intracellular Nitric Oxide in the Hyperproteinuric Phase of Puromycin Nephrosis.2007

    • Author(s)
      Hirayama A.
    • Organizer
      40th annual meeting of the American Society of Nephrology
    • Place of Presentation
      サンフランシスコ(米国)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Presentation] In vivo EPR analysis and imaging of antihypertensive drugs on renal reducing activity.2007

    • Author(s)
      Hirayama A.
    • Organizer
      EPR 2007: A Joint Conference of 12th In Vivo EPR Spectroscopy and Imaging 9th International EPR Spin Trapping/Spin Labeling
    • Place of Presentation
      シカゴ(米国)
    • Year and Date
      2007-04-30
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Presentation] Design of redox polymer-silica nanohybrid materials for effective treatment of renal failure.

    • Author(s)
      Matsumura T, Yaguchi T, Yoshitomi T, Ikeda Y, Ueda A, Hirayama A, Nagasaki Y
    • Organizer
      SPSJ International Polymer Conferences 2014
    • Place of Presentation
      EPHOCAL Tsukuba (Tsukuba, Ibaraki, Japan)
    • Year and Date
      2014-12-02 – 2014-12-04
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] 抗炎症性と 老廃物吸着能を併せ持つシリカ含有レドック スナノ粒子の設計腹膜透析へ展開

    • Author(s)
      松村卓馬, 矢口達也,池田 豊, 吉冨 徹,植田敦志,平山 暁,長崎幸夫
    • Organizer
      つくば医 工連携フォーラム2014
    • Place of Presentation
      つくば国際会議場,つくば
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] 高性能な腹膜透析液の開発を目指したシ リカ含有レドックスナノ粒子の作製と評価

    • Author(s)
      松村卓馬、矢口達也、池田 豊 、吉 冨 徹、平山 暁、植田敦志 ,植田敦志 、長崎 幸夫
    • Organizer
      第23回日本MRS年次大会
    • Place of Presentation
      横浜開港記念会館,横浜情報文化センター,波止場会館,万国橋会議センター,横浜
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] Nano-kidney possessing oxidative stress suppression character.

    • Author(s)
      Nagasaki Y, Yaguchi T, Matsumura T, Yoshitomi T, Ikeda Y, Ueda A, Hirayama A.
    • Organizer
      ASN Kidney Week 2014, 2014 Annual Meeting of the American Society of Nephrology.
    • Place of Presentation
      Philadelphia, PA (USA)
    • Year and Date
      2014-11-13 – 2014-11-16
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] Nanotechnology in, vivo: Redox Polymer Therapeutics

    • Author(s)
      Nagasaki Y
    • Organizer
      40th Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Hawaii Convention Center, Honolulu, Hawaii, U.S.A
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] Novel redox polymer therapeutics for antioxidative injuries

    • Author(s)
      Nagasaki Y
    • Organizer
      17th Biennial Meeting of Society for Free Radical Research International (SFRRI 2014)
    • Place of Presentation
      Kyoto International Conference Center, Sakyo-ku, Kyoto
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] Upper Stream Reactions of Oxidative Stress in Hemodialysis Patients.

    • Author(s)
      Hirayama A, Ueda A, Nagase S, Matsui H, Aoyagi K, Owada S.
    • Organizer
      2013 Annual meeting of the American Society of Nephrology (Kidney Week 2013)
    • Place of Presentation
      Georgia World Congress Center, Atlanta, GA, USA
    • Data Source
      KAKENHI-PROJECT-24591224
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    # of Collaborated Products: 30 results
  • 2.  NAGASE Sohji (10189128)
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    # of Collaborated Products: 19 results
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    # of Collaborated Products: 4 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
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    # of Collaborated Products: 9 results
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    # of Collaborated Products: 3 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
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