ochi hirofumi 越智博文

… Alternative Names

Ochi Hirofumi 越智博文

OCHI Hirofumi 越智博文

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Researcher Number	20325442
Other IDs
External Links
Affiliation (Current)	2025: 愛媛大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 愛媛大学, 医学系研究科, 教授 2019 – 2021: 愛媛大学, 医学系研究科, 准教授 2018: 愛媛大学, 医学系研究科, 講師 2009: 九大, 大学病院, 講師 2008: Kyushu University, 大学病院, 講師 … More 2007: Kyushu University, 大学病院, 助教 2003: 九州大学, 医学部付属病院, 講師 2003: Kyushu University, Department of Neurology, Assistant Prof., 大学病院, 講師 2002: University Hospital, Instructor, 医学部附属病院, 講師 Less
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related / Neurology Except Principal Investigator Neurology
Keywords	Principal Investigator 多発性硬化症 / 個別化治療 / 疾患活動性 / 免疫モニタリング / NfL / GFAP / 濾胞性ヘルパーT細胞 / IL6 / B細胞 / 補体 … More / 末梢性ヘルパーT細胞 / 末梢血濾胞性ヘルパーT細胞 / アストロサイト / AQP4抗体 / 視神経脊髄炎 / IL-10 / Toll様受容体 / Toll様受容体４ / リポ多糖結合タンパク質 / HMGB1 / リポ多糖結合蛋白質 / リポ多糖 / IL10 / 制御性B細胞 / Toll様受容体4 / 脳由来神経栄養因子 / TGF-β / 免疫調節性細胞 / 神経病態免疫学 … More Except Principal Investigator SEREX / hsp105 / Th1 / 多発性硬化症 / transgenic mouse / HLA class II / opticospinal / multiple sclerosis / HSP105 / トランスジェニックマウス / HLAクラスII / 視神経脊髄型 / allergic conjunctivitis / intracellular cytokine / autoimmune disease / Th2 balance / apoptosis / allergy / thymus / myasthenia gravis / アレルギー性結膜炎 / 細胞内サイトカイン / 自己免疫疾患 / Th2バランス / アポトーシス / アレルギー / 胸腺 / 重症筋無力症 / 血漿型PAF-AH / 遺伝子多型 / ミエロパチー / 脊髄炎 / アトピー素因 Less

Immunological monitoring of neuromyelitis optica activity via peripheral blood circulating follicular helper T cellPrincipal Investigator
- Principal Investigator
  
  Ochi Hirofumi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Ehime University
Novel therapy for multiple sclerosis via induction of regulatory B cells targeting Toll-like receptorPrincipal Investigator
- Principal Investigator
  
  Ochi Hirofumi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Ehime University
末梢血単球の機能制御による多発性硬化症の新規治療法開発に関する研究Principal Investigator
- Principal Investigator
  
  越智博文
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Novel therapeutic approach for multiple sclerosis using TGF-β-positive regulatory T cellPrincipal Investigator
- Principal Investigator
  
  OCHI Hirofumi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
アトピー素因を伴う脊髄炎・ミエロパチーにおける疾患感受性遺伝子の検索
- Principal Investigator
  
  KIRA Jun-ichi
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Development of an animal model of opticospinal form of multiple sclerosis using the HLA-DP5 transgenic mice.
- Principal Investigator
  
  KIRA Jun-ichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
STUDY OF ALLERGIC REACTION IN PATHOGENESIS OF MYASTHENIA GRAVIS
- Principal Investigator
  
  MURAI Hiroyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  KYUSHU UNIVERSITY

All 2022 2021 2009 2008 2007

All Journal Article Presentation

[Journal Article] Association of cerebrospinal inflammatory profile with radiological features in newly diagnosed treatment-naive patients with multiple sclerosis2022
- Author(s)
  Ashida Shinji, Kondo Takayuki, Fujii Chihiro, Hamatani Mio, Mizuno Toshiki, Ochi Hirofumi
- Journal Title
  
  Frontiers in Neurology
  
  Volume: 13 Pages: 1012857-1012857
- DOI
  10.3389/fneur.2022.1012857
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07463, KAKENHI-PROJECT-19K16923
[Journal Article] Radiological and Laboratory Features of Multiple Sclerosis Patients With Immunosuppressive Therapy: A Multicenter Retrospective Study in Japan2021
- Author(s)
  Ashida Shinji、Ochi Hirofumi、Hamatani Mio、Fujii Chihiro、Nishigori Ryusei、Kawamura Kazuyuki、Matsumoto Sadayuki、Nakagawa Masanori、Takahashi Ryosuke、Mizuno Toshiki、Kondo Takayuki
- Journal Title
  
  Frontiers in Neurology
  
  Volume: 12 Pages: 749406-749406
- DOI
  10.3389/fneur.2021.749406
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07463
[Journal Article] Hypercomplementemia at relapse in patients with anti-aquaporin-4 antibody2009
- Author(s)
  Doi H, Matsushita T, Isobe N, Matsuoka T, Minohara M, Ochi H, Kira J
- Journal Title
  
  Mult Scler 15(3)
  
  Pages: 304-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590995
[Journal Article] Research Committee of Neuroimmunological Diseases. Temporal changes and geographical differences in multiple sclerosis phenotypes in Japanese : nationwide survey results over 30 years2009
- Author(s)
  Osoegawa M, Kira J, FukazawaT, Fujihara K, Kikuchi S, Matsui M, Kohriyama T, Sobue G, Yamamura T, Itoyama Y, Saida T, Sakata K, Ochi H, Matsuoka T
- Journal Title
  
  Mult Scler 15(2)
  
  Pages: 159-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590995
[Journal Article] Association of the HLA- DPB1*0501 allele with anti-aquaporin-4 antibody positivity in Japanese patients with idiopathic central nervous system demyelinating disorders2009
- Author(s)
  Matsushita T, Matsuoka T, Isobe N, Kawano Y, Minohara M, Shi N, Nishimura Y, Ochi H, Kira J.
- Journal Title
  
  Tissue Antigens 73(2)
  
  Pages: 171-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590995
[Journal Article] Intrathecal upregulation of IFN-gamma and MIP-lbeta in juvenile muscular atrophy of the distal upper extremity2008
- Author(s)
  Tanaka M, Ishizu T, Ochi H, Kawano Y, Ohyagi Y, Kira J
- Journal Title
  
  J Neurol Sci 275(1-2)
  
  Pages: 74-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590995
[Journal Article] Distinct CSF cytokine/chemokine profiles in atopic myelitis and othercauses of myelitis.2008
- Author(s)
  Tanaka M, Matsushita T, Tateishi T, Ochi H, et al
- Journal Title
  
  Neurology 71
  
  Pages: 974-981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590995
[Journal Article] Intrathecal upregulation of IFN-gamma and MlP-1beta in juvenile muscular atrophy of the distal upper extremity2008
- Author(s)
  Tanaka M, Ishizu T, Ochi H, et al
- Journal Title
  
  J Neurol Sci. 275
  
  Pages: 74-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590995
[Journal Article] New immunosuppressive approaches : oral administration of CD3-specificantibody to treat autoimmunity.2008
- Author(s)
  Ochi H, Abraham M, Ishikawa H., et al
- Journal Title
  
  J Neurol Sci. 274
  
  Pages: 9-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590995
[Journal Article] New immunosuppressive approaches : oral administration of CD3-specific antibody to treat autoimmunity2008
- Author(s)
  Ochi H, Abraham M, Ishikawa H, Frenkel D, Yang K, Basso A, Wu H, Chen ML, Gandhi R, Miller A, Maron R, Weiner HL.
- Journal Title
  
  J Neurol Sci 274(1-2)
  
  Pages: 9-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590995
[Journal Article] Heterogeneity and continuum of multiple sclerosis in Japanese according to magnetic resonance imaging findings2008
- Author(s)
  Matsuoka T, Matsushita T, Osoegawa M, Ochi H, Kawano Y, Mihara F, Ohyagi Y, Kira J
- Journal Title
  
  J Neurol Sci 266(1-2)
  
  Pages: 115-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590995
[Journal Article] Distinct CSF cytokine/chemokine profiles in atopic myelitis and other causes of myelitis2008
- Author(s)
  Tanaka M, Matsushita T, Tateishi T, Ochi H, Kawano Y, Mei FJ, Minohara M, Murai H, Kira JI
- Journal Title
  
  Neurology 71(13)
  
  Pages: 974-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590995
[Journal Article] Inhibition of autoimmune diabetes by oral administration of anti-CD3 monoclonal antibody2007
- Author(s)
  Ishikawa H, Ochi H, Chen ML, Frenkel D, Maron R, Weiner HL
- Journal Title
  
  Diabetes 56(8)
  
  Pages: 2103-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590995
[Journal Article] Inhibition of autoimmune diabetes by oral administration of anti-CD3 monoclonal antibody2007
- Author(s)
  Ishikawa H, Ochi H, et. al.
- Journal Title
  
  Diabetes 56(8)
  
  Pages: 2103-2109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590995
[Journal Article] Heterogeneity of aquaporin-4 autoimmunity and spinal cord lesions in multiple sclerosis in Japanese2007
- Author(s)
  Matsuoka T, Matsushita T, Kawano Y, Osoegawa M, Ochi H, Ishizu T, Minohara M, Kikuchi H, Mihara F, Ohyagi Y, Kira J.
- Journal Title
  
  Brain 130
  
  Pages: 1206-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590995
[Presentation] 末梢血免疫担当細胞におけるbrain derived neurotrophic factor(BDNF)産生能と多発性硬化症(MS)病態との関連2009
- Author(s)
  吉村怜、越智博文、松岡健、松下拓也、河野祐治、三野原元澄、吉良潤一
- Organizer
  第21回日本神経免疫学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590995
[Presentation] 末梢血免疫担当細胞におけるbrain derived neurotrophic factor (BDNF)産生能と多発性硬化症(MS)病態との関連.2009
- Author(s)
  吉村怜, 越智博文, 松岡健, ほか
- Organizer
  第21回日本神経免疫学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590995
[Presentation] 通常型多発性硬化症の病態機序と治療多発性硬化症(MS)病態へのbrain derived neurotrophic factor(BDNF)の関与2008
- Author(s)
  吉村怜、越智博文、松岡健、松下拓也、河野祐治、三野原元澄、吉良潤一
- Organizer
  第20回日本神経免疫学会学術集会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-19590995
[Presentation] 腸管免疫と全身免疫のクロストークからみた実験的自己免疫性脳脊髄炎の制御2007
- Author(s)
  越智博文、吉良潤一、Weiner Howard
- Organizer
  第19回日本神経免疫学会学術集会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-19590995
[Presentation] 経口抗CD3抗体による実験的自己免疫性脳脊髄炎の抑制2007
- Author(s)
  越智博文、吉良潤一、Weiner Howard
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19590995
[Presentation] New immunosuppressive approaches2007
- Author(s)
  Ochi H.
- Organizer
  European Charcot Foundation Symposium 2007
- Place of Presentation
  Fiuggi,Italy
- Year and Date
  2007-11-30
- Data Source
  KAKENHI-PROJECT-19590995
[Presentation] New immunosuppressive aproaches2007
- Author(s)
  Ochi H
- Organizer
  European Charcot Foundation Symposium 2007
- Place of Presentation
  Fiuggi, Italy
- Year and Date
  2007-11-30
- Data Source
  KAKENHI-PROJECT-19590995

1. KIRA Jun-ichi (40183305)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. MURAI Hiroyuki (80325464)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 小副川学 (60380614)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. 藤井ちひろ (00516065)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. NISHIMURA Yasuharu (10156119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 菊池仁志 (60322765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 岡田洋一郎 (10808356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 濱谷美緒 (20890809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 芦田真士 (60884202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

ochi hirofumi 越智 博文

Ochi Hirofumi 越智 博文

OCHI Hirofumi 越智 博文

Research Projects

Research Products

Co-Researchers

Immunological monitoring of neuromyelitis optica activity via peripheral blood circulating follicular helper T cellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel therapy for multiple sclerosis via induction of regulatory B cells targeting Toll-like receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

末梢血単球の機能制御による多発性硬化症の新規治療法開発に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel therapeutic approach for multiple sclerosis using TGF-β-positive regulatory T cellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アトピー素因を伴う脊髄炎・ミエロパチーにおける疾患感受性遺伝子の検索

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of an animal model of opticospinal form of multiple sclerosis using the HLA-DP5 transgenic mice.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

STUDY OF ALLERGIC REACTION IN PATHOGENESIS OF MYASTHENIA GRAVIS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Association of cerebrospinal inflammatory profile with radiological features in newly diagnosed treatment-naive patients with multiple sclerosis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Radiological and Laboratory Features of Multiple Sclerosis Patients With Immunosuppressive Therapy: A Multicenter Retrospective Study in Japan2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hypercomplementemia at relapse in patients with anti-aquaporin-4 antibody2009

Author(s)

Journal Title

Data Source

[Journal Article] Research Committee of Neuroimmunological Diseases. Temporal changes and geographical differences in multiple sclerosis phenotypes in Japanese : nationwide survey results over 30 years2009

Author(s)

Journal Title

Data Source

[Journal Article] Association of the HLA- DPB1*0501 allele with anti-aquaporin-4 antibody positivity in Japanese patients with idiopathic central nervous system demyelinating disorders2009

Author(s)

Journal Title

Data Source

[Journal Article] Intrathecal upregulation of IFN-gamma and MIP-lbeta in juvenile muscular atrophy of the distal upper extremity2008

Author(s)

Journal Title

Data Source

[Journal Article] Distinct CSF cytokine/chemokine profiles in atopic myelitis and othercauses of myelitis.2008

Author(s)

Journal Title

Data Source

[Journal Article] Intrathecal upregulation of IFN-gamma and MlP-1beta in juvenile muscular atrophy of the distal upper extremity2008

Author(s)

ochi hirofumi 越智博文

Ochi Hirofumi 越智博文

OCHI Hirofumi 越智博文