Hasegawa Akiko 長谷川顕子 (山路顕子)

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… Alternative Names

長谷川顕子ハセガワアキコ (ヤマジアキコ)

山路顕子

Yamaji-Hasegawa Akiko 長谷川顕子

長谷川顕子(山路顕子) ハセガワアキコ

HASEGAWA Akiko 長谷川顕子

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Researcher Number	20332314
External Links
Affiliation (Current)	2026: 国立研究開発法人理化学研究所, 脳神経科学研究センター, 専任研究員
Affiliation (based on the past Project Information) *help	2026: 国立研究開発法人理化学研究所, 脳神経科学研究センター, 専任研究員 2022 – 2024: 国立研究開発法人理化学研究所, 脳神経科学研究センター, 専任研究員 2018 – 2020: 国立研究開発法人理化学研究所, 脳神経科学研究センター, 専任研究員 2011 – 2012: 独立行政法人理化学研究所, 小林脂質生物学研究室, 専任研究員 2004 – 2006: 独立行政法人理化学研究所, 辻本細胞生化学研究室, 研究員 2003: 独立行政法人理化学研究所, スフィンゴ脂質機能研究チーム, フロンティア研究員 2001 – 2002: 理化学研究所, スフィンゴ脂質機能研究チーム, 基礎科学特別研究員
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Biological pharmacy / Biological pharmacy Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 変異株 / 脂質解析プローブ / 形質膜 / フリップ・フロップ / ホスファチジルセリン / 脂質輸送 / ライセニン / スフィンゴミエリン / 炎症 / セラミド1リン酸 … More / ガン / 生理活性脂質 / グルコース化脂質 / 生体膜 / 非対称分布 / 脂質動態 / フロップ / フリップ / リン脂質 / 細胞毒性 / ホスホリパーゼ / 細胞死 / 蛍光標識脂質 / 脂質配向性 / 耐性株 / コレステロール / タイトジャンクション / 上皮細胞 / 脂質ラフト / 毒素 / 細胞内輸送 / 特異的プローブ / ラフト … More Except Principal Investigator フリップ-フロップ / 膜結合性毒素 / 膜ドメイン / 脂質プローブ / 脂質ラフト / スフィンゴミエリン / 糖脂質 / 抗ガン剤 / 多剤耐性 / P-糖蛋白質 / リゾビスホスファチジン酸 / コレステロール / 脂質ドメイン / エンドサイトーシス Less

膵臓ガンにおけるセラミド1リン酸を介した細胞間コミュニケーションの分子機構の解明Principal Investigator
- Principal Investigator
  
  長谷川顕子 (山路顕子)
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Institute of Physical and Chemical Research
Development of an analytical probe for ceramide-1-phosphate, a novel bioactive lipid, and its application to pathological researchPrincipal Investigator
- Principal Investigator
  
  Hasegawa Akiko
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Institute of Physical and Chemical Research
Development of probes for glucosylated lipids, novel bioactive lipids, and their application for lipid function analysisPrincipal Investigator
- Principal Investigator
  
  Yamaji-Hasegawa Akiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Institute of Physical and Chemical Research
Analysis of the molecular mechanism of flip-flop that regulates the asymmetric distribution of lipids in the plasma membranesPrincipal Investigator
- Principal Investigator
  
  HASEGAWA Akiko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  The Institute of Physical and Chemical Research
生体膜における脂質配向性を制御するフリップ・フロップの分子機構の解析Principal Investigator
- Principal Investigator
  
  長谷川顕子 (山路顕子)
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The Institute of Physical and Chemical Research
脂質特異的プローブを用いた細胞内脂質の分布と動態の解析
- Principal Investigator
  
  小林俊秀
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
スフィンゴミエリンの細胞内輸送機講と細胞機能への関与の解析Principal Investigator
- Principal Investigator
  
  長谷川顕子 (山路顕子)
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The Institute of Physical and Chemical Research
スフィンゴミエリン特異的プローブを用いたラフト制御機構の解析Principal Investigator
- Principal Investigator
  
  長谷川顕子 (山路顕子)
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The Institute of Physical and Chemical Research

All 2013 2011 2006 2005 Other

All Journal Article Presentation Patent

[Journal Article] Asymmetric distribution of phospholipids in biomembranes2006
- Author(s)
  Akiko Yamaji-Hasegawa et al.
- Journal Title
  
  Biological ＆ Pharmaceutical Bulletin 29 (8)
  
  Pages: 1547-1553
- Data Source
  KAKENHI-PROJECT-17790082
[Journal Article] Asymmetric distribution of phospholipids in biomembranes2006
- Author(s)
  Akiko Yamaji-Hasegawa et al.
- Journal Title
  
  Biological & Pharmaceutical Bulletin (印刷中)
- Data Source
  KAKENHI-PROJECT-17790082
[Journal Article] Fungal metabolite sulfamisterin suppresses sphingolipid synthesis through inhibition of serine palmitoyltransferase2005
- Author(s)
  Akiko Yamaji-Hasegawa et al.
- Journal Title
  
  Biochemistry 44(1)
  
  Pages: 268-277
- Data Source
  KAKENHI-PROJECT-15790063
[Journal Article] 脂質ラフトの多様性2005
- Author(s)
  山路-長谷川顕子
- Journal Title
  
  実験医学(増刊) 23(印刷中)
- Data Source
  KAKENHI-PROJECT-15790063
[Journal Article] 脂質ラフトの多様性2005
- Author(s)
  山路-長谷川顕子, 他
- Journal Title
  
  実験医学 23(6)
  
  Pages: 865-870
- Data Source
  KAKENHI-PROJECT-17790082
[Journal Article] Fungal metabolite sulfamisterin suppresses sphingolipid synthesis through inhibition of serine palmitoyltrnasferase2005
- Author(s)
  Yamaji-Hasegawa A
- Journal Title
  
  Biochemistry 44
  
  Pages: 268-277
- Data Source
  KAKENHI-PROJECT-16044247
[Patent] スフィンゴミエリンの検出方法2005
- Inventor(s)
  小林俊秀, 長谷川顕子
- Industrial Property Rights Holder
  独立行政法人理化学研究所
- Industrial Property Number
  2005-024779
- Filing Date
  2005-02-01
- Data Source
  KAKENHI-PROJECT-15790063
[Presentation] 14-3-3 regulates the transbilayer movement of phosphatidylserine by altering actin assembly2013
- Author(s)
  Akiko Yamaji-Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi
- Organizer
  Lipid-protein interaction. From molecules to cells
- Place of Presentation
  理化学研究所(埼玉)(招待講演)
- Year and Date
  2013-05-24
- Data Source
  KAKENHI-PROJECT-23659047
[Presentation] 細胞形質膜の内外層非対称性を制御するフリップ・フロップ機構2011
- Author(s)
  山路顕子
- Organizer
  理研シンポジウム「第３回　生体分子の分離・解析法の進展　膜タンパク質への応用」(招待講演)
- Place of Presentation
  理化学研究所（埼玉）
- Data Source
  KAKENHI-PROJECT-23659047
[Presentation] 細胞形質膜の内外層非対称性を制御するフリップ・フロップ機構2011
- Author(s)
  山路顕子
- Organizer
  理研シンポジウム「第3回生体分子の分離・解析法の進展膜タンパク質への応用」
- Place of Presentation
  理化学研究所(埼玉)(招待講演)
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-23659047
[Presentation] 14-3-3 regulates the transbilayer movement of phosphatidylserine by altering actin assembly
- Author(s)
  Akiko Yamaji-Hasegawa
- Organizer
  RIKEN symposium "Lipid-protein interaction. From molecules to cells"
- Place of Presentation
  理化学研究所（埼玉）
- Invited
- Data Source
  KAKENHI-PROJECT-23659047

1. 小林俊秀 (60162004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 庄籠秀彦 (80391986)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 石塚玲子 (60342747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 牧野麻美 (20373368)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 村手源英 (30311369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hasegawa Akiko 長谷川 顕子 (山路 顕子)

長谷川 顕子 ハセガワ アキコ (ヤマジ アキコ)

山路 顕子

山路顕子

Yamaji-Hasegawa Akiko 長谷川 顕子

長谷川 顕子(山路顕子) ハセガワ アキコ

HASEGAWA Akiko 長谷川 顕子

Research Projects

Research Products

Co-Researchers

膵臓ガンにおけるセラミド1リン酸を介した細胞間コミュニケーションの分子機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of an analytical probe for ceramide-1-phosphate, a novel bioactive lipid, and its application to pathological researchPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of probes for glucosylated lipids, novel bioactive lipids, and their application for lipid function analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the molecular mechanism of flip-flop that regulates the asymmetric distribution of lipids in the plasma membranesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

生体膜における脂質配向性を制御するフリップ・フロップの分子機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脂質特異的プローブを用いた細胞内脂質の分布と動態の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

スフィンゴミエリンの細胞内輸送機講と細胞機能への関与の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

スフィンゴミエリン特異的プローブを用いたラフト制御機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Asymmetric distribution of phospholipids in biomembranes2006

Author(s)

Journal Title

Data Source

[Journal Article] Asymmetric distribution of phospholipids in biomembranes2006

Author(s)

Journal Title

Data Source

[Journal Article] Fungal metabolite sulfamisterin suppresses sphingolipid synthesis through inhibition of serine palmitoyltransferase2005

Author(s)

Journal Title

Data Source

[Journal Article] 脂質ラフトの多様性2005

Author(s)

Journal Title

Data Source

[Journal Article] 脂質ラフトの多様性2005

Author(s)

Journal Title

Data Source

[Journal Article] Fungal metabolite sulfamisterin suppresses sphingolipid synthesis through inhibition of serine palmitoyltrnasferase2005

Author(s)

Hasegawa Akiko 長谷川顕子 (山路顕子)

長谷川顕子ハセガワアキコ (ヤマジアキコ)

山路顕子

Yamaji-Hasegawa Akiko 長谷川顕子

長谷川顕子(山路顕子) ハセガワアキコ

HASEGAWA Akiko 長谷川顕子