MASUKO Takashi 益子崇

… Alternative Names

益子崇マスコタカシ

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Researcher Number	20339245
Other IDs
Affiliation (based on the past Project Information) *help	2012: 日本大学, 薬学部, 准教授 2011: 日本大学, 薬学部, 講師 2009: Nihon University, 薬学部, 講師 2008: Nihon University, 薬学部, 助教 2005 – 2006: 日本大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator 神経細胞死 / NMDA受容体 / 脳虚血 / アルツハイマー病 / ASIC1a / ビグアニド誘導体 / 酸感受性イオンチャネル / 受容体 / 神経伝達物質 / ポリアミン誘導体 … More / 神経創薬 / Xenopus oocytes / Channel block / Memantine / Cyclophane / NMDA receptor / Alzheimer's disease / グルタミン酸受容体 / 薬理学 / 脳神経疾患 / 神経科学 Less

Research Projects
(3 results)
Research Products
(19 results)

The nerve cell protection effect by the biguanide derivativesPrincipal Investigator
- Principal Investigator
  
  MASUKO Takashi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Nihon University
A study on nerve cell protection effect of the polyamine derivativesPrincipal Investigator
- Principal Investigator
  
  MASUKO Takashi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Nihon University
シクロファン及びその誘導体による神経細胞保護効果に関する研究Principal Investigator
- Principal Investigator
  
  益子崇
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Nihon University

All 2013 2012 2011 2010 2009 2007 Other

All Journal Article Presentation

[Journal Article] Antagonism of NMDA receptors by butanesulfonyl-homospermine guanidine and neuroprotective effects in in vitro and in vivo2012
- Author(s)
  Takashi Masuko, Toyofumi Suzuki, Muneharu Miyake, Kuniko Kusama-Eguchi, Yasuo Kizawa, Kazuo Tomono, Keiko Kashiwagi, Kazuei Igarashi, Tadashi Kusama
- Journal Title
  
  Neuroscience Letters
  
  Volume: 506 Pages: 251-255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700452
[Journal Article] Neuroprotection by tosyl-polyamine derivatives through the inhibition of ionotropic glutamate receptors.2009
- Author(s)
  MASUKO T., NAMIKI R., NEMOTO Y., MIYAKE M., KIZAWA Y., SUZUKI T., KASHIWAGI K., IGARASHI K., KUSAMA T.
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 331(2)
  
  Pages: 522-530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700340
[Journal Article] Neuroprotection by tosyl-polyamine derivatives througy the inhibition of ionotropic gtutamate receptors.2009
- Author(s)
  Masuko T., et al.
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 331
  
  Pages: 522-530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700340
[Journal Article] Cyclophane and acyclic cyclophane : Novel channel blockers of N-methyl-D-aspartate receptor2007
- Author(s)
  Masuko T., Nagaoka H., Miyake M., Metori K., Kizawa Y., Kashiwagi K., Igarashi K., Kusama T.
- Journal Title
  
  Neurochemistry international 50
  
  Pages: 443-449
- Data Source
  KAKENHI-PROJECT-17700358
[Presentation] グルタミン酸受容体及び酸感受性イオンチャネルに対するピラジン及びアルキルを有するビグアニド誘導体の阻害効果2013
- Author(s)
  益子崇、小原尋乃、栗原弘紀、佐藤明日香、佐美三和昌、鈴木優生、三宅宗晴、鈴木豊史、伴野和夫、草間-江口國子、木澤靖夫、草間貞
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-23700452
[Presentation] Inhibitory effects of new synthesized biguanide derivatives with pyrazine and alkyl groups to both NMDAR and ASIC1a activities2013
- Author(s)
  益子崇、三宅宗晴、鈴木豊史、伴野和夫、草間-江口國子、木澤靖夫、草間貞
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-23700452
[Presentation] Biguanide derivatives with pyrazine and benzene groups: new synthesized dual channel blockers with both potent NMDAR and ASIC1a inhibitory activities.2012
- Author(s)
  Takashi MASUKO, Muneharu MIYAKE, Toyofumi SUZUKI, Kazuo TOMONO, Kuniko KUSAMA-EGUCHI, Yasuo KIZAWA, Tadashi KUSAMA
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23700452
[Presentation] ピラジンとベンゼンを有する新規合成ビグアニド誘導体による酸感受性イオンチャンネル及びグルタミン酸受容体の阻害作用2012
- Author(s)
  益子　崇、三宅宗晴、鈴木豊史、草間ー江口國子、伴野和夫、木澤靖夫、草間　貞
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23700452
[Presentation] Biguanide derivatives with pyrazine and benzene groups: new synthesized dual channel blockers with both potent NMDAR and ASIC1a inhibitory activities2012
- Author(s)
  益子崇、三宅宗晴、鈴木豊史、伴野和夫、草間-江口國子、木澤靖夫、草間貞
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-23700452
[Presentation] ピラジンとベンゼンを有する新規合成ビグアニド誘導体による酸感受性イオンチャネル及びグルタミン酸受容体の阻害作用2012
- Author(s)
  益子崇、三宅宗晴、鈴木豊史、草間-江口國子、木澤靖夫、草間貞
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23700452
[Presentation] ピラジンを有するビグアニド誘導体の酸感受性イオンチャンネル及びグルタミン酸受容体に対する影響2011
- Author(s)
  益子　崇、三宅宗晴、鈴木豊史、伴野和夫、草間國子、木澤靖夫、草間　貞
- Organizer
  第125回日本薬理学会関東部会
- Place of Presentation
  船橋
- Data Source
  KAKENHI-PROJECT-23700452
[Presentation] 酸感受性イオンチャンネル及びNMDA受容体に対するビグアニド誘導体の阻害作用2011
- Author(s)
  益子　崇、三宅宗晴、鈴木豊史、伴野和夫、草間國子、木澤靖夫、草間　貞
- Organizer
  第13回応用薬理シンポジウム
- Place of Presentation
  船橋
- Data Source
  KAKENHI-PROJECT-23700452
[Presentation] Neuroprotective properties of butanesulfonyl-polyamine with guanidine group in different models of ischemia, in vitor and vivo.2010
- Author(s)
  吉田周平、益子崇、鈴木豊史、三宅宗晴、草間-江口國子、木澤靖夫、伴野和夫、草間貞
- Organizer
  第83回日本藥理学会
- Place of Presentation
  大阪
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-20700340
[Presentation] Neuroprotective properties of butanesulfonyl-polyamine with guanidint group in different mobels of ischemia, in vitro and in vivo.2010
- Author(s)
  益子崇
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-20700340
[Presentation] Neuincaubacrion by polyamine derivatives via mhibilim of Nmethyr-D-aspartate receptors2009
- Author(s)
  益子崇
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-20700340
[Presentation] Neuroprotection by polyaminederivatives via inhibition of N-methyl-D-aspartate receptors.2009
- Author(s)
  益子崇、並木里絵、根本雄太、三宅宗晴、草間-江口國子、木澤靖夫、柏木敬子、五十嵐一衛、草間貞
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-20700340
[Presentation] ポリアミン誘導体によるNMDA受容体活性阻害を介した脳保護効果2009
- Author(s)
  益子崇、鈴木豊史、並木里絵、長岡裕樹、宮崎由美子、三宅宗晴、草間國子、木澤靖夫、柏木敬子、五十嵐一衛、伴野和夫、草間貞
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-20700340
[Presentation] グルタミン酸受容体及び酸感受性イオンチャネルに対するピラジン及びアルキルを有するビグアニド誘導体の阻害効果
- Author(s)
  益子　崇
- Organizer
  日本薬学会133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23700452
[Presentation] Inhibitory effects of new synthesized biguanide derivatives with pyrazine and alkyl groups to both NMDAR and ASIC1a activities.
- Author(s)
  益子　崇
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23700452

MASUKO Takashi 益子 崇

益子 崇 マスコ タカシ

Research Projects

Research Products

The nerve cell protection effect by the biguanide derivativesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study on nerve cell protection effect of the polyamine derivativesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

シクロファン及びその誘導体による神経細胞保護効果に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Antagonism of NMDA receptors by butanesulfonyl-homospermine guanidine and neuroprotective effects in in vitro and in vivo2012

Author(s)

Journal Title

Data Source

[Journal Article] Neuroprotection by tosyl-polyamine derivatives through the inhibition of ionotropic glutamate receptors.2009

Author(s)

Journal Title

Data Source

[Journal Article] Neuroprotection by tosyl-polyamine derivatives througy the inhibition of ionotropic gtutamate receptors.2009

Author(s)

Journal Title

Data Source

[Journal Article] Cyclophane and acyclic cyclophane : Novel channel blockers of N-methyl-D-aspartate receptor2007

Author(s)

Journal Title

Data Source

[Presentation] グルタミン酸受容体及び酸感受性イオンチャネルに対するピラジン及びアルキルを有するビグアニド誘導体の阻害効果2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Inhibitory effects of new synthesized biguanide derivatives with pyrazine and alkyl groups to both NMDAR and ASIC1a activities2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Biguanide derivatives with pyrazine and benzene groups: new synthesized dual channel blockers with both potent NMDAR and ASIC1a inhibitory activities.2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] ピラジンとベンゼンを有する新規合成ビグアニド誘導体による酸感受性イオンチャンネル及びグルタミン酸受容体の阻害作用2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Biguanide derivatives with pyrazine and benzene groups: new synthesized dual channel blockers with both potent NMDAR and ASIC1a inhibitory activities2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ピラジンとベンゼンを有する新規合成ビグアニド誘導体による酸感受性イオンチャネル及びグルタミン酸受容体の阻害作用2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ピラジンを有するビグアニド誘導体の酸感受性イオンチャンネル及びグルタミン酸受容体に対する影響2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 酸感受性イオンチャンネル及びNMDA受容体に対するビグアニド誘導体の阻害作用2011

Author(s)

Organizer

MASUKO Takashi 益子崇

益子崇マスコタカシ