BANDO Toshikazu 板東俊和

… Alternative Names

坂東俊和バンドウトシカズ

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Researcher Number	20345284
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2023: 京都大学, 理学研究科, 准教授 2012 – 2016: 京都大学, 理学(系)研究科(研究院), 准教授 2013 – 2014: 京都大学, 理学研究科, 准教授 2012: 京都大学, 大学院・理学研究科, 准教授 2010: 京都大学, 理学研究科, 准教授 … More 2007 – 2010: Kyoto University, 大学院・理学研究科, 准教授 2006: Kyoto University, Graduate School of Science, Professor, 大学院理学研究科, 助教授 2005: 京都大学, 大学院・理学研究科, 助教授 2004: 京都大学, 助手 2003 – 2004: 京都大学, 大学院・理学研究科, 助手 2002: 東京医科歯科大学, 生体材料工学研究所, 助手 Less
Review Section/Research Field	Principal Investigator Living organism molecular science / Basic Section 37030:Chemical biology-related / Chemical biology Except Principal Investigator Living organism molecular science / Chemistry related to living body / Biological Sciences / Medium-sized Section 37:Biomolecular chemistry and related fields / Drug development chemistry / Chemical biology / Carcinogenesis
Keywords	Principal Investigator Py-Imポリアミド / 配列特異的アルキル化 / 塩基配列認識 / 結合性リガンド / DNA構造認識 / DNA配列認識 / DNA塩基配列認識 / 特定遺伝子制御 / Py-Im ポリアミド / 核酸 … More / 合成化学 / 機能性分子 / 生物有機化学 / テロメア配列 / 配列特異的蛍光発色 / 特定遺伝子発現制御 / ピロール-イミダゾールポリアミド / 配列特異的DNAアルキル化 / ピロール・イミダゾールポリアミド / 遺伝子発現制御 … More Except Principal Investigator 遺伝子発現制御 / DNA / 修飾塩基 / Py-Imポリアミド / photoreaction / Z form DNA / 構造解析 / 光反応 / Z型DNA / 遺伝子発現 / DNAナノ構造体 / iPS細胞 / エピジェネティクス / 5-ハロウラシル / 核酸 / ピロールイミダゾールポリアミド / テーラーメード抗がん剤 / 塩基配列認識 / 配列特異的DNAアルキル化 / ピロール-イミダゾールポリアミド / ミトコンドリア / AFM解析 / ヌクレオソーム / 生物有機化学 / ケミカルバイオロジー / G-quadruplex / modified base / structural analysis / 修飾塩某 / DNA四重鎖 / 5-halouracil / B-Z transition / DNA probe / DNA conformation / H abstraction / DNA損傷 / DNAプローブ / DNA構造 / エピゲノム / マルチターゲットな小分子化合物 / DNAベースの治療 / 天然分子を模倣した化合物 / 人口遺伝子スイッチ / 合成生物学 / 小分子 / 細胞リプログラミング / 人工遺伝子スイッチ / 初期化 / 細胞初期化 / エピジェネティックス / 内在性遺伝子の再発現 / 山中因子 / SAHA / リプログラミング / 癌 / エピジェネティク / ヒストン修飾 / がん / ヒストン脱アセチル化酵素阻害剤 / ヒストンアセチル化 / 白血病 / PIポリアミド / DNAアルキル化 / 細胞老化 / テロメア / 光反応性 / 構造機能解析 / 蛋白質 / 配列特異的アルキル化 / コンビナトリアル合成 / DNA塩基配列 / DNAチップ Less

DNA配列や構造を認識する結合性リガンドの開発Principal Investigator
- Principal Investigator
  
  板東俊和
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Kyoto University
Development of molecules that control gene networks and their application to cells
- Principal Investigator
  
  SUGIYAMA Hiroshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Kyoto University
Nature-inspired small molecules for regulation of therapeutically important genes
- Principal Investigator
  
  NAMASIVAYAM Ganesh Pandian
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto University
Control and elucidation of gene expression at a molecular level
- Principal Investigator
  
  SUGIYAMA Hiroshi
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyoto University
The development of novel functional Py-Im polyamide conjugates for sequence-specific gene regulationPrincipal Investigator
- Principal Investigator
  
  Bando Toshikazu
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Kyoto University
Development of programmable small molecules capable of switching ON the transcriptional machinery of pluripotency genes.
- Principal Investigator
  
  NAMASIVAYAM Ganesh Pandian
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical biology
- Research Institution
  Kyoto University
Development of cancer therapy inducing histone acethylation at the specific region of cancer genome
- Principal Investigator
  
  NAGASE Hiroki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Carcinogenesis
- Research Institution
  Chiba Cancer Center (Research Institute)
The development of the functional polyamides to regulate specific DNA-protein structurePrincipal Investigator
- Principal Investigator
  
  BANDO Toshikazu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Kyoto University
Cell-biological analysis of sequence-specific DNA alkylating molecules.
- Principal Investigator
  
  KEN-ICHI Shinohara
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Kyoto University
Chemical Biology of DNA Structure and Functions
- Principal Investigator
  
  SUGIYAMA Hiroshi
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyoto University
生物学的評価を指向したアルキル化ポリアミドの合成研究Principal Investigator
- Principal Investigator
  
  板東俊和
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  Kyoto University
Tailor-made Antitumor Agents based on DNA Sequence
- Principal Investigator
  
  SUGIYAMA Hiroshi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Chemical biology based determination of DNA local structures in vivo
- Principal Investigator
  
  SUGIYAMA Hiroshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  Kyoto University
反応性Py-Imポリアミドによる遺伝子機能解析法の確立Principal Investigator
- Principal Investigator
  
  板東俊和
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  Kyoto University
Photochemical probe of DNA local structures
- Principal Investigator
  
  SUGIYAMA Hiroshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  Kyoto University
DNA塩基配列を正確に読み取るテーラーメード抗がん剤の開発
- Principal Investigator
  
  SUGIYAMA Hiroshi
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
  Tokyo Medical and Dental University

[Book] 基礎ケミカルバイオロジー(化学同人)2011
- Author(s)
  杉山弘, 板東俊和
- Total Pages
  195
- Data Source
  KAKENHI-PROJECT-19205023
[Book] 基礎ケミカルバイオロジー2011
- Author(s)
  杉山弘, 板東俊和
- Total Pages
  195
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-20611008
[Book] 基礎ケミカルバイオロジー2011
- Author(s)
  杉山弘、板東俊和
- Total Pages
  195
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-20611008
[Book] 基礎ケミカルバイオロジー2011
- Author(s)
  杉山弘、板東俊和
- Total Pages
  195
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-19205023
[Journal Article] A cyclic pyrrole-imidazole polyamide reduces pathogenic RNA in CAG/CTG triplet repeat neurological disease models2023
- Author(s)
  Ikenoshita Susumu、Matsuo Kazuya、Yabuki Yasushi、Kawakubo Kosuke、Asamitsu Sefan、Hori Karin、Usuki Shingo、Hirose Yuki、Bando Toshikazu、Araki Kimi、Ueda Mitsuharu、Sugiyama Hiroshi、Shioda Norifumi
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 133 Issue: 22
- DOI
  10.1172/jci164792
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K13857, KAKENHI-PROJECT-22KJ2516, KAKENHI-PROJECT-22K05353, KAKENHI-PROJECT-21K06579, KAKENHI-PROJECT-22K19297, KAKENHI-PROJECT-22KJ1695, KAKENHI-PLANNED-23H03851, KAKENHI-PROJECT-21H04705, KAKENHI-PROJECT-23H00373, KAKENHI-PROJECT-23K24245
[Journal Article] Substitution to hydrophobic linker and formation of host-guest complex enhanced the effect of synthetic transcription factor made of pyrrole-imidazole polyamide.2023
- Author(s)
  Junnosuke Hatanaka and Kaori Hashiya and Toshikazu Bando and Hiroshi Sugiyama
- Journal Title
  
  Bioorganic & medicinal chemistry
  
  Volume: 81 Pages: 117208-117208
- DOI
  10.1016/j.bmc.2023.117208
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05353, KAKENHI-PLANNED-20H05936, KAKENHI-PROJECT-21H04705
[Journal Article] RNA G-quadruplex organizes stress granule assembly through DNAPTP6 in neurons2023
- Author(s)
  Asamitsu Sefan、Yabuki Yasushi、Matsuo Kazuya、Kawasaki Moe、Hirose Yuki、Kashiwazaki Gengo、Chandran Anandhakumar、Bando Toshikazu、Wang Dan Ohtan、Sugiyama Hiroshi、Shioda Norifumi
- Journal Title
  
  Science Advances
  
  Volume: 9 Issue: 8
- DOI
  10.1126/sciadv.ade2035
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06579, KAKENHI-PROJECT-22K05353, KAKENHI-PROJECT-22K19297, KAKENHI-PROJECT-20H03393, KAKENHI-PROJECT-20J00520, KAKENHI-PROJECT-22KJ1695, KAKENHI-PROJECT-22KJ2516, KAKENHI-PROJECT-20K15417, KAKENHI-PUBLICLY-21H00207, KAKENHI-PLANNED-20H05936, KAKENHI-PROJECT-21H04705, KAKENHI-PROJECT-21H02580
[Journal Article] Twelve Colors of Streptavidin-Fluorescent Proteins (SA-FPs): A Versatile Tool to Visualize Genetic Information in Single-Molecule DNA2022
- Author(s)
  Jin Yu、Bae Jaeyoung、Kim Tehee Yurie、Hwang Hyeseung、Kim Taesoo、Yu Myungheon、Oh Hyesoo、Hashiya Kaori、Bando Toshikazu、Sugiyama Hiroshi、Jo Kyubong
- Journal Title
  
  Analytical Chemistry
  
  Volume: 94 Issue: 48 Pages: 16927-16935
- DOI
  10.1021/acs.analchem.2c04344
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05936, KAKENHI-PROJECT-21H04705
[Journal Article] Targeted elimination of mutated mitochondrial DNA by a multi-functional conjugate capable of sequence-specific adenine alkylation2022
- Author(s)
  Hidaka Takuya、Hashiya Kaori、Bando Toshikazu、Pandian Ganesh N.、Sugiyama Hiroshi
- Journal Title
  
  Cell Chemical Biology
  
  Volume: 29 Issue: 4 Pages: 1-6
- DOI
  10.1016/j.chembiol.2021.08.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03349, KAKENHI-PROJECT-22KJ3130, KAKENHI-PROJECT-21H04705, KAKENHI-PLANNED-20H05936
[Journal Article] N-terminal Cationic Modification of Linear Pyrrole-Imidazole Polyamide Improves Its Binding to DNA.2022
- Author(s)
  Junnosuke Hatanaka and Yuki Hirose and Kaori Hashiya and Toshikazu Bando and Hiroshi Sugiyama
- Journal Title
  
  Chembiochem : a European journal of chemical biology
  
  Volume: 23 Issue: 14
- DOI
  10.1002/cbic.202200124
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05353, KAKENHI-PROJECT-22KJ1695, KAKENHI-PLANNED-20H05936, KAKENHI-PROJECT-21H04705
[Journal Article] Application of DNA‐Alkylating Pyrrole‐Imidazole Polyamides for Cancer Treatment2021
- Author(s)
  Maeda Rina、Bando Toshikazu、Sugiyama Hiroshi
- Journal Title
  
  ChemBioChem
  
  Volume: 22 Issue: 9 Pages: 1538-1545
- DOI
  10.1002/cbic.202000752
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04705, KAKENHI-PLANNED-20H05936
[Journal Article] Strong and Specific Recognition of CAG/CTG Repeat DNA (5’‐dWGCWGCW‐3’) by a Cyclic Pyrrole‐Imidazole Polyamide2021
- Author(s)
  Hirose Yuki、Ohno Tomo、Asamitsu Sefan、Hashiya Kaori、Bando Toshikazu、Sugiyama Hiroshi
- Journal Title
  
  ChemBioChem
  
  Volume: 23 Issue: 2
- DOI
  10.1002/cbic.202100533
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20J00520, KAKENHI-PROJECT-20K15417, KAKENHI-PROJECT-22KJ1695, KAKENHI-PROJECT-21H04705, KAKENHI-PLANNED-20H05936
[Journal Article] Advancing small-molecule-based chemical biology with next-generation sequencing technologies2015
- Author(s)
  C. Anandhakumar, S. Kizaki, Ganesh N. Pandian, T. Bando, and H. Sugiyama.
- Journal Title
  
  ChemBioChem
  
  Volume: 16 Issue: 1 Pages: 20-38
- DOI
  10.1002/cbic.201402556
- NAID
  120006460115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670055
[Journal Article] A synthetic transcriptional activator of genes associated with retina in human dermal fibroblasts2015
- Author(s)
  J. Syed, C. Anandhakumar, Ganesh N. Pandian, J. Taniguchi, S. Sato, K. Hashiya, G. Kashiwazaki, T. Bando, and H. Sugiyama
- Journal Title
  
  ChemBioChem
  
  Volume: In press Issue: 10 Pages: 1497-1501
- DOI
  10.1002/cbic.201500140
- NAID
  120005670900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670055, KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-24225005
[Journal Article] A novel detection technique of polyamide binding sites by photo-induced electron transfer in BrU substituted DNA2015
- Author(s)
  Saha, A., Hashiya, F., Kizaki, S., Asamitsu, S., Hashiya, K., Bando, T., Sugiyama, H.
- Journal Title
  
  Chem. Commun.
  
  Volume: 51 Issue: 77 Pages: 14485-14488
- DOI
  10.1039/c5cc05104e
- NAID
  120006462491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-24225005
[Journal Article] Selective Targeting of the KRAS Codon 12 Mutation Sequence by Pyrrole–Imidazole Polyamide seco-CBI Conjugates.2015
- Author(s)
  Taylor RD, Chandran A, Kashiwazaki G, Hashiya K, Bando T, Nagase H and Sugiyama H.
- Journal Title
  
  Chemistry.
  
  Volume: 21 Issue: 42 Pages: 14996-5003
- DOI
  10.1002/chem.201501870
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21737, KAKENHI-ORGANIZER-25112001, KAKENHI-PUBLICLY-26112517, KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-26290060, KAKENHI-PROJECT-24225005
[Journal Article] Integrating epigenetic modulators into NanoScript for enhanced chondrogenesis of stem cells2015
- Author(s)
  S. Patel, T. Pongkulapa, P. Yin, Ganesh N. Pandian, C. Rathnam, T. Bando, T. Vaijayanthi, H. Sugiyama and K-B. Lee.
- Journal Title
  
  Journal of the American Chemical Society (ACS Publications)
  
  Volume: 137 Issue: 14 Pages: 4598-4601
- DOI
  10.1021/ja511298n
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670055, KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-24225005
[Journal Article] Tandem trimer pyrrole-imidazole polyamide probes targeting 18 base pairs in human telomere sequences2015
- Author(s)
  Yusuke Kawamoto, Asuka Sasaki, Kaori Hashiya, Satoru Ide, Toshikazu Bando, Kazuhiro Maeshima, Hiroshi Sugiyama
- Journal Title
  
  Chemical Science
  
  Volume: 6 Issue: 4 Pages: 2307-2312
- DOI
  10.1039/c4sc03755c
- NAID
  120005841416
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23115005, KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-24225005
[Journal Article] A Synthetic DNA-binding Domain Guides Distinct Chromatin-modifying Small Molecules to Activate an Identical Gene Network.2015
- Author(s)
  Han, L., Pandian, G, N., Chandran, A., Sato, S., Taniguchi, J., Kashiwazaki, G., Sawatani, Y., Hashiya, K., Bando, T., Xu, Y., Qian, X., Sugiyama, H.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 54 Issue: 30 Pages: 8700-8703
- DOI
  10.1002/anie.201503607
- NAID
  120006460099
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24225005, KAKENHI-PROJECT-24310155
[Journal Article] Rational design of specific binding hairpin Py-Im polyamides targeting human telomere sequences.2015
- Author(s)
  Guo, C. X ., Kawamoto, Y., Asamitsu, S., Sawatani, Y., Hashiya, K., Bando, T., Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 23 Issue: 4 Pages: 855-860
- DOI
  10.1016/j.bmc.2014.12.025
- NAID
  120005555482
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-24225005
[Journal Article] Preclinical Study of Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Hypertrophic Scars in a Common Marmoset Primate Model.2015
- Author(s)
  Igarashi J, Fukuda N, Inoue T, Nakai S, Saito K, Fujiwara K, Matsuda H, Ueno T, Matsumoto Y, Watanabe T, Nagase H, Bando T Sugiyama H Itoh T Soma M.
- Journal Title
  
  PlosOne.
  
  Volume: 10(5) Issue: 5 Pages: e0125295-e0125295
- DOI
  10.1371/journal.pone.0125295
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-25112001, KAKENHI-PUBLICLY-26112517, KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-26290060, KAKENHI-PROJECT-24225005
[Journal Article] Chemical Modification of a Synthetic Small Molecule Boosts its Biological Efficacy against Pluripotency Genes in Mouse Fibroblast.2014
- Author(s)
  Saha, A.; Pandian, G. N.; Sato, S.; Taniguchi, J.; Kawamoto, Y.; Hashiya, K.; Bando, T.; Sugiyama, H.
- Journal Title
  
  ChemMedChem
  
  Volume: 9 Issue: 10 Pages: 2374-2380
- DOI
  10.1002/cmdc.201402117
- NAID
  120005657928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-26670055, KAKENHI-PROJECT-24225005
[Journal Article] Sequence-Specific DNA Alkylation and Transcriptional Inhibition by Long-Chain Hairpin Pyrrole-Imidazole Polyamide-Chlorambucil Conjugates Targeting CAG/CTG Trinucleotide Repeats.2014
- Author(s)
  Asamitsu, S.; Kawamoto, Y.; Hashiya, F.; Hashiya, K.; Yamamoto, M.; Kizaki, S.; Bando, T.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 22 Issue: 17 Pages: 4646-4657
- DOI
  10.1016/j.bmc.2014.07.019
- NAID
  120005474526
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-24225005
[Journal Article] Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate.2014
- Author(s)
  Hiraoka K, Inoue T, Taylor RD, Watanabe T, Koshikawa N, Yoda H, Shinohara K, Takatori A, Sugimoto H, Maru Y, Denda T, Fujiwara K, Balmain A, Ozaki T, Bando T, Sugiyama H, Nagase H.
- Journal Title
  
  Nat. Commun.
  
  Volume: 6 Issue: 1 Pages: 6706-6706
- DOI
  10.1038/ncomms7706
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-25112001, KAKENHI-PUBLICLY-25134718, KAKENHI-PROJECT-25871150, KAKENHI-PUBLICLY-26112517, KAKENHI-PROJECT-26290060, KAKENHI-PROJECT-15K08412, KAKENHI-PROJECT-26350977, KAKENHI-PROJECT-25461573, KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-24225005
[Journal Article] Sequence-specific DNA Alkylation by Tandem Py-Im Polyamide Conjugates.2014
- Author(s)
  Taylor, R, D.; Kawamoto, Y.; Hashiya, K.; Bando, T.; Sugiyama, H.
- Journal Title
  
  Chem. Asian J.
  
  Volume: 9 Issue: 9 Pages: 2527-2533
- DOI
  10.1002/asia.201402331
- NAID
  120005647509
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-24225005
[Journal Article] Specific Alkylation of Human Telomere Repeat Sequences by a Tandem-Hairpin Motif of Pyrrole-Imidazole Polyamides with Indole-Seco-CBI2014
- Author(s)
  Yamamoto, M.; Bando, T.; Kawamoto, Y.; Taylor, R. D.; Hashiya, K.; Sugiyama, H.
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 25 Issue: 3 Pages: 552-559
- DOI
  10.1021/bc400567m
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-24225005
[Journal Article] Targeted Suppression of EVI1 Oncogene Expression by Sequence-Specific Pyrrole-imidazole Polyamide2014
- Author(s)
  Junetha, S.; Pandian, G, N.; Sato, S.; Taniguchi, J.; Anandhakumar, C.; Hashiya, K.; Bando, T.; Sugiyama, H.
- Journal Title
  
  Chem. Biol.
  
  Volume: 23 Issue: 10 Pages: 1370-1380
- DOI
  10.1016/j.chembiol.2014.07.019
- NAID
  120005512270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-26670055, KAKENHI-PROJECT-24225005
[Journal Article] Distinct DNA-based epigenetic switches trigger differential transcriptional activation in human dermal fibroblasts2014
- Author(s)
  Pandian GN, Nagase H
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 3843-3843
- DOI
  10.1038/srep03843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300344, KAKENHI-PROJECT-24225005, KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-24710261, KAKENHI-PUBLICLY-25134718
[Journal Article] Next-Generation Sequencing Studies Guide the Design of Pyrrole-Imidazole Polyamides with Improved Binding Specifictiy by the Addition of β-alanine.2014
- Author(s)
  Anandhakumar, C.; Li, Y.; Kizaki, S.; Pandian, G. N.; Hashiya, K.; Bando, T.; Sugiyama, H.
- Journal Title
  
  ChemBioChem
  
  Volume: 15 Issue: 18 Pages: 2647-2651
- DOI
  10.1002/cbic.201402497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-26670055, KAKENHI-PROJECT-24225005
[Journal Article] NanoScript: A Nanoparticle-Based Artificial Transcription Factor for Effective Gene Regulation.2014
- Author(s)
  Patel, S.; Jung, D.; Yin, P.; Carlton, P.; Yamamoto, M.; Bando, T.; Sugiyama, H.; Lee, K, B.
- Journal Title
  
  ACS Nano.
  
  Volume: 8 Issue: 9 Pages: 8959-8967
- DOI
  10.1021/nn501589f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-24225005
[Journal Article] Construction and Characterization of Cy3- or Cy5-Conjugated Hairpin Pyrrole / Imidazole Polyamide Binding to DNA in the Nucleosome2014
- Author(s)
  Han, Y-W.; Tsunaka, Y.; Yokota, H.; Matsumoto, T.; Kashiwazaki, G.; Morinaga, H.; Hashiya, K.; Bando, T.; Sugiyama, H.; Harada, Y.
- Journal Title
  
  Biomater. Sci.
  
  Volume: 2 Issue: 3 Pages: 297-307
- DOI
  10.1039/c3bm60202h
- NAID
  120005587835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24225005, KAKENHI-PROJECT-24570182, KAKENHI-PROJECT-25440008
[Journal Article] Identification of a Small Molecule that Turns `ON` the Pluripotency Gene Circuitry in Human Fibroblasts.2014
- Author(s)
  Pandian, G, N.; Sato, S.; Anandhakumar, C.; Taniguchi, J.; Takashima, K.; Syed, J; Han, L.; Saha, A.; Bando, T.; Nagase, H.; Sugiyama, H.
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 9 Issue: 12 Pages: 2729-2736
- DOI
  10.1021/cb500724t
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-26670055, KAKENHI-PROJECT-24225005
[Journal Article] Structural Evaluation of Tandem Hairpin Pyrrole-Imidazole Polyamides Recognizing Human Telomeres.2014
- Author(s)
  Akiyoshi Hirata, Kiyoshi Nokihara, Yusuke Kawamoto, Toshikazu Bando, Asuka Sasaki, Satoru Ide, Kazuhiro Maeshima, Takeshi Kasama, and Hiroshi Sugiyama
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 136 Issue: 32 Pages: 11546-11554
- DOI
  10.1021/ja506058e
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23115005, KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-24225005
[Journal Article] Sequence-Specific DNA Recognition by Dimerized Cysteine Cyclic Pyrrole-Imidazole Polyamides2014
- Author(s)
  Yamamoto, M.; Bando, T.; Morinaga, N.; Kawamoto, Y.; Hashiya, K.; Sugiyama, H.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 20 Issue: 3 Pages: 752-759
- DOI
  10.1002/chem.201302482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24225005, KAKENHI-PROJECT-24310155
[Journal Article] A Synthetic Small Molecule Enforces Targeted Transcriptional Activation of　Germ Cell Genes in a Human Somatic Cell.2013
- Author(s)
  Han L, Pandian GN, Junetha S, Sato S, Anandhakumar C, Taniguchi J, Saha A, Bando T, Nagase H and Sugiyama H.
- Journal Title
  
  Angewandte Chemie
  
  Volume: 52 Issue: 50 Pages: 13410-13413
- DOI
  10.1002/anie.201306766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300344, KAKENHI-PROJECT-24225005, KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-24710261, KAKENHI-PUBLICLY-25134718
[Journal Article] RNA binding properties of novel gene silencing pyrrole-imidazole polyamides.2013
- Author(s)
  Iguchi A, Fukuda N, Takahashi T, Watanabe T, Matsuda H, Nagase H, Bando T, Sugiyama H, Shimizu K.
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: 36 Pages: 1152-1158
- NAID
  130003361484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300344
[Journal Article] Sequence-Specific DNA Alkylation Targeting for Kras Codon 13 Mutation by Pyrrole-Imidazole Polyamide seco-CBI Conjugates2013
- Author(s)
  Taylor RD, Asamitsu S, Takenaka T, Yamamoto M, Hashiya K, Kawamoto Y, Bando T, Nagase H, Sugiyama H
- Journal Title
  
  Chemistry
  
  Volume: 20 Issue: 5 Pages: 1310-1317
- DOI
  10.1002/chem.201303295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300344, KAKENHI-PROJECT-24225005, KAKENHI-PROJECT-24310155
[Journal Article] Solid-Supported DNA for Asymmetric Synthesis: a Stepping-Stone toward Practical Applications2013
- Author(s)
  Han, Y-W.; Kashiwazaki, G.; Morinaga, H.; Matsumoto, T.; Hashiya, K.; Bando, T.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21 Issue: 17 Pages: 5436-5441
- DOI
  10.1016/j.bmc.2013.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24225005, KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-25440008
[Journal Article] RNA binding properties of novel gene silencing pyrrole-imidazole polyamides2013
- Author(s)
  Iguchi A, Fukuda N, Takahashi T, Watanabe T, Matsuda H, Nagase H, Bando T, Sugiyama H, Shimizu K
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 36(7) Pages: 1152-8
- NAID
  130003361484
- Data Source
  KAKENHI-PROJECT-23300344
[Journal Article] Sequence-specific electron injection into DNA from an intermolecular electron donor2013
- Author(s)
  Morinaga H, Takenaka T, Hashiya F, Kizaki S, Hashiya K, Toshikazu B, Sugiyama H.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: (印刷中) Issue: 8 Pages: 4724-4728
- DOI
  10.1093/nar/gkt123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J00177, KAKENHI-PROJECT-24225005, KAKENHI-PROJECT-24310155
[Journal Article] Design of a new fluorescent probe : Pyrrole/Imidazole hairpin polyamides with pyrene conjugation at theirγ-turn2013
- Author(s)
  T. Vaijayanthi, T. Bando, K. Hashiya, Ganesh N. Pandian, et al.
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 21 Pages: 852-855
- NAID
  120005241442
- Data Source
  KAKENHI-PROJECT-24710261
[Journal Article] A Synthetic Small Molecule Enforces T argeted Transcriptional Activation of Germ Cell Genes in a Human Somatic Cell2013
- Author(s)
  Han L, Pandian GN, Junetha S, Sato S, Anandhakumar C, Taniguchi J, Saha A, Bando T, Nagase H and Sugiyama H
- Journal Title
  
  Angewandte Chemie
  
  Volume: 52(50) Pages: 13410-3
- Data Source
  KAKENHI-PROJECT-23300344
[Journal Article] Structural Evaluation of Tandem Hairpin Pyrrole-Imidazole Polyamides Recognizing Human Telomeres.2013
- Author(s)
  Yusuke Kawamoto, Toshikazu Bando, Fukumi Kamada, Yue Li, Kaori Hashiya, Kazuhiro Maeshima, and Hiroshi Sugiyama
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 135 Issue: 44 Pages: 16468-77
- DOI
  10.1021/ja406737n
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23370078, KAKENHI-PROJECT-24225005, KAKENHI-PROJECT-24310155
[Journal Article] Synthesis and Biological Evaluation of a Targeted DNA-Binding Transcriptional Activator with HDAC8 Inhibitory Activity2013
- Author(s)
  Saha, A.; Pandian, G. N.; Sato, S.; Taniguchi, J.; Hashiya, K.; Bando, T.;Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21 Issue: 14 Pages: 4201-4209
- DOI
  10.1016/j.bmc.2013.05.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24225005, KAKENHI-PROJECT-24310155
[Journal Article] Design of a New Fluorescent Probe: Pyrrole/Imidazole Hairpin Polyamides with Pyrene Conjugation at Their γ-Turn2013
- Author(s)
  Vaijayanthi, T.; Bando, T.; Hashiya, K.; Pandian, G. N.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21 Issue: 4 Pages: 852-855
- DOI
  10.1016/j.bmc.2012.12.018
- NAID
  120005241442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24225005
[Journal Article] Binding of hairpin pyrrole and imidazole polyamides to DNA : relationship between torsion angle and association rate constants2012
- Author(s)
  Han YW, Matsumoto T, Yokota H, Kashiwazaki G, Morinaga H, Hashiya K, Bando T, Harada Y, Sugiyama H.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 40 Issue: 22 Pages: 11510-11517
- DOI
  10.1093/nar/gks897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J00177, KAKENHI-PROJECT-23770204, KAKENHI-PROJECT-24225005, KAKENHI-PROJECT-24570182, KAKENHI-PUBLICLY-23118711
[Journal Article] Development of Programmable Small DNA-Binding Molecules with Epigenetic Activity for Induction of Core Pluripotency Genes2012
- Author(s)
  Pandian, G. N.; Ohtsuki, A.; Bando, T.; Sato, S.; Hashiya, K.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 20 Issue: 8 Pages: 2656-2660
- DOI
  10.1016/j.bmc.2012.02.032
- NAID
  120004025596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24225005
[Journal Article] A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblasts2012
- Author(s)
  Pandian GN, Nakano Y, Sato S, Morinaga H, Bando T, Nagase H, Sugiyama H
- Journal Title
  
  Sci Rep
  
  Volume: 2:544 Issue: 1 Pages: 544-544
- DOI
  10.1038/srep00544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J00177, KAKENHI-PROJECT-23300344, KAKENHI-PROJECT-24225005, KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-24710261
[Journal Article] Synthesis of Pyrrole-Imidazole Polyamide Seco-CBI Conjugates with a Vinyl Linker recognizing 7 bp DNA sequence.2012
- Author(s)
  Takagaki, T.; Bando, T.; Sugiyama, H.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 135 Issue: 31 Pages: 13074-13081
- DOI
  10.1021/ja3044294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24225005, KAKENHI-PROJECT-24310155
[Journal Article] Progress and Prospects of Pyrrole-Imidazole Polyamide-Fluorophore Conjugate as Sequence-Selective DNA Probes2012
- Author(s)
  Vaijayanthi, T.; Bando, T.; Pandian, G. N.; Sugiyama, H.
- Journal Title
  
  ChemBioChem
  
  Volume: 13 Issue: 15 Pages: 2170-2185
- DOI
  10.1002/cbic.201200451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24225005
[Journal Article] Sequence-Selective Single-Molecule Alkylation with a Pyrrole-Imidazole Polyamide Visualized in a DNA Nanoscaffold2012
- Author(s)
  T. Yoshidome, M. Endo, G. Kashiwazaki, K. Hidaka, T. Bando, H. Sugiyama
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: 134 Issue: 10 Pages: 4654-4660
- DOI
  10.1021/ja209023u
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21603008, KAKENHI-PROJECT-22310081, KAKENHI-PLANNED-24104002, KAKENHI-PROJECT-24310097, KAKENHI-PROJECT-24310155
[Journal Article] Progress and prospects of pyrrole-imidazole polyamide-fluorophore conjugate as sequence-selective DNA probes2012
- Author(s)
  T. Vaijayanthi, T. Bando, Ganesh N. Pandian et al.
- Journal Title
  
  ChemBioChem
  
  Volume: 13 Pages: 2170-2185
- Data Source
  KAKENHI-PROJECT-24710261
[Journal Article] Comparative Analysis of DNA Alkylation by Conjugates between Pyrrole-Imidazole Hairpin Polyamides and Chlorambucil or seco-CBI.2010
- Author(s)
  Minoshima, M.; Bando, T.; Shinohara, K.; Kashiwazaki, K.; Nishijima, S.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem. vol.18
  
  Pages: 1236-1243
- NAID
  120001887644
- Data Source
  KAKENHI-PROJECT-20710164
[Journal Article] Chiral Wedge Moleculeinhibits Telomerase Activity.2010
- Author(s)
  Shinohara, K., Sannohe,Y., Kaieda, S., Tanaka, K., Osuga, H., Xu, Y., Bando, T., Sugiyama, H.
- Journal Title
  
  J.Am.Chem.Soc. 132
  
  Pages: 3778-3782
- Data Source
  KAKENHI-PROJECT-19205023
[Journal Article] Alkylation of a Human Telomere Sequence by Heterotrimeric Chlorambucil PI Polyamide Conjugates2010
- Author(s)
  Kashiwazaki, G.; Bando, T.; Sugiyama, H.
- Journal Title
  
  Bioorg.Med.Chem.
  
  Volume: 18 Pages: 2887-2893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Chiral Wedge Molecule inhibits Telomerase Activity.2010
- Author(s)
  Shinohara, K.; Sannohe, Y.; Kaieda, S.; Tanaka, K.; Osuga, H.; Xu, Y.; Bando, T.; Sugiyama, H.
- Journal Title
  
  J. Am. Chem Soc. vol.132
  
  Pages: 3778-3782
- Data Source
  KAKENHI-PROJECT-20710164
[Journal Article] Potent Activity against K562 Cells by Polyamide - seco -CBI Conjugates Targeting Histone H4 Genes.2010
- Author(s)
  Minoshima, M.; Chou, J.C.; Lefebvre, S.; Bando, T.; Shinohara, K.; Gottesfeld, J.M.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem. vol.18
  
  Pages: 168-174
- Data Source
  KAKENHI-PROJECT-20710164
[Journal Article] Comparative Analysis of DNA Alkylation by Conjugates between Pyrrole-Imidazole Hairpin Polyamides and Chlorambucil or seco-CBI.2010
- Author(s)
  Minoshima, M., Bando, T., Shinohara, K., Kashiwazaki, K., Nishijima, S., Sugiyama, H.
- Journal Title
  
  Bioorg.Med.Chem. 18
  
  Pages: 1236-1243
- NAID
  120001887644
- Data Source
  KAKENHI-PROJECT-19205023
[Journal Article] Alkylation of a Human Telomere Sequence by Heterotrimeric Chlorambucil PI Polyamide Conjugates.2010
- Author(s)
  Kashiwazaki, G., Bando, T., Shinohara, K., Mioshima, M., Kumamoto, H. Nishijima, S., Sugiyama, H.
- Journal Title
  
  Bioorg med.chem. 18
  
  Pages: 2887-2893
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Cell Permeability of Py-Im Polyamide-Fluorescein Conjugates : Influence of Molecular Size and Py/Im Content.2010
- Author(s)
  Nishijima, S., Shinohara, K., Bando,T., Minoshima, M., Kashiwazaki, G., Sugiyama, H.
- Journal Title
  
  Bioorg.Med.Chem. 18
  
  Pages: 978-983
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Comparative Analysis of DNA Alkylation by Conjugates between Pyrrole-Imidazole Hairpin Polyamides and Chlorambucil or seco-CBI.Bioorg2010
- Author(s)
  Minoshima, M.; Bando, T.; Sugiyama, H.
- Journal Title
  
  Bioorg.Med.Chem.
  
  Volume: 18 Pages: 1236-1243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Potent Activity Against K562 Cells by Polyamide-seco-CBI Conjugates Targeting Histone H4 Genes2010
- Author(s)
  Minoshima, M.; Bando, T.; Sugiyama, H.
- Journal Title
  
  Bioorg.Med.Chem.
  
  Volume: 18 Pages: 168-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Anticancer Activities of Alkylating Pyrrole-Imidazole Polyamides with Specific Sequence Recognition2010
- Author(s)
  Ken-ichi Shinohara, Toshikazu Bando, Hiroshi Sugiyama
- Journal Title
  
  Anti-Cancer Drug 21
  
  Pages: 228-242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710164
[Journal Article] Alkylation of a Human Telomere Sequence by Heterotrimeric Chlorambucil PI Polyamide Conjugates.2010
- Author(s)
  Kashiwazaki, G., Bando, T., Shinohara, K., Mioshima, M., Kumamoto, H., Nishijima, S., Sugiyama, H.
- Journal Title
  
  Bioorg.Med.Chem. 18
  
  Pages: 2887-2893
- Data Source
  KAKENHI-PROJECT-19205023
[Journal Article] Comparative Analysis of DNA Alkylation by Conjugates between Pyrrole-Imidazole Hairpin Polyamides and Chlorambucil or seco-CBI.2010
- Author(s)
  Minoshima,M., Bando, T., Shinohara, K., Kashiwazaki, K., Nishijima, S., Sugiyama, H.
- Journal Title
  
  Bioorg.Med.Chem. 18
  
  Pages: 1236-1243
- NAID
  120001887644
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Chiral wedge molecule inhibits telomerase activity2010
- Author(s)
  Ken-ichi Shinohara, Yuta Sannohe, Shuji Kaieda, Ken-ichi Tanaka, Hideji Osuga, Hidetoshi Tahara, Yan Xu, Takashi Kawase, Toshikazu Bando, Hiroshi
- Journal Title
  
  Journal of the American Chemical Society 132
  
  Pages: 3778-3782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710164
[Journal Article] Alkylation of a Human Telomere Sequence by Heterotrimeric Chlorambucil PI Polyamide Conjugates.2010
- Author(s)
  Kashiwazaki, G.; Bando, T.; Shinohara, K.; Mioshima, M.; Kumamoto, H.; Nishijima, S.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem. vol.18
  
  Pages: 2887-2893
- Data Source
  KAKENHI-PROJECT-20710164
[Journal Article] A Chiral Wedge Molecule Inhibits Telomerase Activity.2010
- Author(s)
  Shinohara, K., Sannohe, Y., Kaieda, S., Tanaka, K., Osuga, H., Tahara, H., Xu, Y., Kawase, T., Bando, T., Sugiyama, H.
- Journal Title
  
  J.Am.Chem.Soc. 132
  
  Pages: 3778-3782
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Potent Activity against K562 Cells by Polyamide-seco-CBI Conjugates Targeting Histone H4 Genes. Bioorg.2010
- Author(s)
  Minoshima, M., Chou, J.C., Lefebvre, S., Bando, T., Shinohara, K., Gottesfeld, J.M., Sugiyama, H.
- Journal Title
  
  Med.Chem. 18
  
  Pages: 168-174
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Alkylation of a human telomere sequence by heterotrimeric chlorambucil PI polyamide conjugates.2010
- Author(s)
  Gengo Kashiwazaki, Toshikazu Bando, Ken-ichi Shinohara, Masafumi Minoshima, Hana Kumamoto, Shigeki Nishijima, Hiroshi Sugiyama
- Journal Title
  
  Bioorganic & Medicinal Chemistry 18
  
  Pages: 2887-2893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710164
[Journal Article] Cell Permeability of Py-Im Polyamide - Fluorescein Conjugates: Influence of Molecular Size and Py/Im Content.2010
- Author(s)
  Nishijima, S; Shinohara, K.; Bando, T.; Minoshima, M.; Kashiwazaki, G.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem. vol.18
  
  Pages: 978-983
- Data Source
  KAKENHI-PROJECT-20710164
[Journal Article] Anticancer Activities of Alkylating Pyrrole-Imidazole Polyamides with Specific Sequence Recognition.2010
- Author(s)
  Shinohara, K.; Bando, T.; Sugiyama, H.
- Journal Title
  
  Anti - Cancer Drug vol.21
  
  Pages: 228-242
- Data Source
  KAKENHI-PROJECT-20710164
[Journal Article] Cooperative alkylation of double-strand human telomere repeat sequences by PI polyamides with 11-base-pair recognition based on a heterotrimeric design2009
- Author(s)
  G.Kashiwazaki, T.Bando^*, et. al.
- Journal Title
  
  Bioorg. Med. Chem. 17
  
  Pages: 1393-1397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Cooperative Alkylation of Double-strand Human Telomere Repeat Sequences by PI Polyamides with 11-Base-pair Recognition Based on a Heterotrimeric Design.2009
- Author(s)
  Kashiwazaki, G. Bando, T.; Shinohara, K.; Minoshima, M.; Nishijima, S.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem. vol.17
  
  Pages: 1393-1397
- Data Source
  KAKENHI-PROJECT-20710164
[Journal Article] Cooperative Alkylation of Double-strand Human Telomere Repeat Sequences by PI Polyamides with 11-Base-pair Recognition Based on a Heterotrimeric Design.2009
- Author(s)
  Kashiwazaki, G.; Bando, T.; Shinohara, K.; Minoshima, M.; Nishijima, S.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem. 17
  
  Pages: 1393-1397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Cooperative Alkylation of Double-strand Human Telomere Repeat Sequences by PI Polyamides with 11-Base-pair Recognition Based on a Heterotrimeric Design2009
- Author(s)
  Kashiwazaki, G. Bando, T. ; Shinohara, K. ; Minoshima, M. ; Nishijima, S. ; Sugiyama, H.
- Journal Title
  
  Bioorganic Medicinal Chemistry 17
  
  Pages: 1393-1397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710164
[Journal Article] Synthesis and Properties of Polyamide - SAHA Conjugate.2009
- Author(s)
  Ohtsuki, A.; Kimura, M.T.; Minoshima, M.; Suzuki, T.; Ikeda, M.; Bando, T.; Nagase, H.; Shinohara, K.; Sugiyama, H.
- Journal Title
  
  Tetrahedron Lett. vol.50
  
  Pages: 7288-7292
- Data Source
  KAKENHI-PROJECT-20710164
[Journal Article] Eukaryotic DNA Polymerases α, β and ε Incorporate Guanine Opposite 2, 2, 4-Triamino-5 (2H) -oxazolone2009
- Author(s)
  K.Kino, T.Bando, et. al.
- Journal Title
  
  ChemBioChem 10
  
  Pages: 2613-2616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Development of a Molecule-Recognized Promoter DNA Sequence for Inhibition of HER2 Expression.2009
- Author(s)
  Suzuki, T.; Asami, Y.; Takahashi, T.; Wang, X.; Watanabe, T.; Bando, T.; Sugiyama, H.; Fukuda, N.; Nagase, H.
- Journal Title
  
  J. Antibiot. 62
  
  Pages: 339-341
- NAID
  10030635628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Cooperative alkylation of double-strand human telomere repeat sequences by PI polyamides with 11-base-pair recognition based on a heterotrimeric design, Bioorg.2009
- Author(s)
  Kashiwazaki, G., Bando, T., Shinohara, K., Minoshima, M., Nishijima, S., Sugiyama, H.
- Journal Title
  
  Med.Chem. 17
  
  Pages: 1393-1397
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Cooperative Alkylation of Double strand Human Telomere Repeat Sequences by PI Polyamides with 11-Base-pair Recognition Based on a Heterotrimeric Design.2009
- Author(s)
  Kashiwazaki, G., Bando, T., Shinohara, K., Minoshima, M., Nishijima, S., Sugiyama, H.
- Journal Title
  
  Bioorg.Med.Chem. 17
  
  Pages: 1393-1397
- Data Source
  KAKENHI-PROJECT-19205023
[Journal Article] Synthesis and Properties of Polyamide-SAHA Conjugate.2009
- Author(s)
  Ohtsuki, A., Kimura, M.T., Minoshima, M., Suzuki, T., Ikeda, M., Bando, T., Nagase, H., Shinohara, K., Sugiyama, H.
- Journal Title
  
  Tetrahedron Lett. 50
  
  Pages: 7288-7292
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Development of a Molecule-Recognized Promoter DNA Sequence for Inhibition of HER2 Expression.2009
- Author(s)
  Suzuki, T., Asami, Y., Takahashi, T., Wang, X., Watanabe, T., Bando, T., Sugiyama, H., Fukuda, N., Nagase, H.
- Journal Title
  
  J.Antibiot. 62
  
  Pages: 339-341
- NAID
  10030635628
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Synthesis and Properties of PI Polyamide-SAHA Conjugate.2009
- Author(s)
  Ohtsuki, A.; Kimura, M.T.; Minoshima, M.; Suzuki, T.; Ikeda, M.; Bando, T.; Nagase, H.; Shinohara, K.; Sugiyama, H.
- Journal Title
  
  Tetrahedron Lett. 50
  
  Pages: 7288-7292
- NAID
  120001741230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Synthesis and Properties of Polyamide-SAHA Conjugate2009
- Author(s)
  A.Ohtsuki, T.Bando, et. al.
- Journal Title
  
  Tetrahedron Lett. 50
  
  Pages: 7288-7292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Perylene-Conjugated Pyrrole Polyamide as a Sequence-Specific Fluorescent Probe.2008
- Author(s)
  Fujimoto, J.; Bando, T.; Minoshima, M.; Kashiwazaki, G.; Nishijima, S.; Shinohara, K.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem. 16
  
  Pages: 9741-9744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Pyrrole-Imidazole hairpin polyamides with high affinity at 5'-CGCG-3' DNA sequence; Influence of cytosine methylation on binding2008
- Author(s)
  Minoshima, M., Bando, T., Sasaki, S., Fujimoto, J., Sugiyama, H.
- Journal Title
  
  Nucleic Acids Res. 36
  
  Pages: 2889-2894
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Perylene-Conjugated Pyrrole Polyamide as a Sequence-Specific Fluorescent Probe2008
- Author(s)
  Fujimoto, J. ; Bando, T. ; Minoshima, M. ; Kashiwazaki, G. ; Nishijima, S. ; Shinohara. K. ; Sugiyama, H.
- Journal Title
  
  Bioorganic & Medicinal Chemistry 16
  
  Pages: 9741-9749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710164
[Journal Article] Sequence-Specific Alkylation by Y-shaped and Tandem Hairpin Pyrrole-Imidazole Polyamides2008
- Author(s)
  Sasaki, S., Bando, T., Minoshima, M., Shinohara, K., Sugiyama, H.
- Journal Title
  
  Chem.Eur.J. 14
  
  Pages: 864-870
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Seauence-Specific Alkylation by Y-shaped and Tandem Hairpin Pyrrole-Imidazole Polyamides2008
- Author(s)
  Sugiyama H.; Bando, T.
- Journal Title
  
  Chem. Eur. J. 18
  
  Pages: 864-870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Detection of Triplet Repeat Sequences in the Double-Stranded DNA using Pyrene-Functionalized Pyrrole-Imidazole Polyamides with Rigid Linkers.2008
- Author(s)
  Fujimoto, J.; Bando, T.; Uchida, S.; Iwasaki, M.; Shinohara, K.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem. 16
  
  Pages: 5899-5907
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Detection of Triplet Repeat Sequences in the Double - Stranded DNA using Pyrene - Functionalized Pyrrole - Imidazole Polyamides with Rigid Linkers.2008
- Author(s)
  Fujimoto, J.; Bando, T.; Minoshima, M.; Uchida, S.; Iwasaki, M.; Shinohara, K.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem. vol.16
  
  Pages: 5899-5907
- Data Source
  KAKENHI-PROJECT-20710164
[Journal Article] Development of Pyrrole-Imidazole Polyamide for Specific Regulation of Human Aurora kinase A and B Gene Expression2008
- Author(s)
  Takahashi, T., Asami, Y., Kitamura, E., Suzuki, T., Wang, X., Igarashi, J., Morohashi, A., Shinojima, Y., Kanou, H., Saito, K., Takasu, T., Nagase, H., Harada, Y., Kuroda, K., Watanabe, T., Kumamoto, S., Aoyama, T., Matsumoto, Y., Bando, T., Sugiyama, H., Yoshida-Noro, C., Fukuda, N., Hayashi, N.
- Journal Title
  
  Chem.Biol. 15
  
  Pages: 829-841
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Requirement of β-alanine components in sequence-specific DNA alkylation by pyrrole-imidazole conjugates with seven-base pair recognition, Bioorg.2008
- Author(s)
  Bando, T., Minoshima, M., Kashiwazaki, G., Shinohara, K., Sasaki, S., Fujimoto, J., Ohtsuki, A., Murakami, M., Nakazono, S., Sugiyama, H.
- Journal Title
  
  Med.Chem. 16
  
  Pages: 2286-2291
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Peryrene-Conjugated Pyrrole polyamides as a Sequence-specific Fluorescent Probe, Bioorg.2008
- Author(s)
  Fujimoto, J., Bando, T., Minoshima,M., Kashiwazaki, G., Nishijima, S., Shinohara, K., Sugiyama, H.
- Journal Title
  
  Med.Chem. 16
  
  Pages: 9741-9744
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Sequence-Specific Alkylation by Y-shaped and Tandem Hairpin Pyrrole-Imidazole Polyamides2008
- Author(s)
  Bando, T.; Sugiyama H.
- Journal Title
  
  Chem. Eur. J. 18
  
  Pages: 864-870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18651107
[Journal Article] Requirement of b-Alanine Components in Sequence-Specific DNA Alkylation by Pyrrole-Imidazole Conjugates with Seven-Base Pair Recognition2008
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  Bioorganic & Medicinal Chemistry 16
  
  Pages: 2286-2291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Pyrrole-Imidazole Hairpin Polyamides with High Affinity at 5'-CGCG-3' DNA Sequence; Influence of Cytosine Methylation on Binding.2008
- Author(s)
  Minoshima, M.: Bando, T.; Sasaki, S.; Fujimoto, J.; Sugiyama, H.
- Journal Title
  
  Nucleic. Acids. Res. 36
  
  Pages: 2889-2894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Perylene - Conjugated Pyrrole Polyamide as a Sequence-Specific Fluorescent Probe.2008
- Author(s)
  Fujimoto, J.; Bando, T.; Minoshima, M.; Kashiwazaki, G.; Nishijima, S.; Shinohara, K.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem. vol.16
  
  Pages: 9741-9744
- Data Source
  KAKENHI-PROJECT-20710164
[Journal Article] Sequence-Specific Alkylation by Y-shaped and Tandem Hairpin Pyrrole-Imidazole Polyamides2008
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  Chem. Eur. J. 18
  
  Pages: 864-870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Requirement of b-Alanine Components in Sequence-Specific DNA Alkylation by Pyrrole-Imidazole Conjugates with Seven-Base Pair Recognition2008
- Author(s)
  Sugiyama H.; Bando, T.
- Journal Title
  
  Bioorgatic & Medicinal Chemistry 16
  
  Pages: 2286-2291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Requirement of β-Alanine Components in Sequence-Specific DNA Alkylation by Pyrrole-Imidazole Conjugates with Seven-Base Pair Recognition.2008
- Author(s)
  Bando, T.; Minoshima, M.; Kashiwazaki, G.; Shinohara, K.; Sasaki, S.; Fujimoto, J.; Ohtsuki, A.; Murakami, M.; Nakazono, S.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem. 16
  
  Pages: 2286-2291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Detection of triplet repeat sequences in double-stranded DNA using pyrene-functionalized pyrrole-imidazole polyamides with rigid linkers, Bioorg.2008
- Author(s)
  Fujimoto, J., Bando, T., Minoshima, M., Uchida, S., Iwasaki, M., Shinohara, K., Sugiyama, H.
- Journal Title
  
  Med.Chem. 16
  
  Pages: 5899-5907
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Sequence-Specific Alkylation by Y-Shaped and Tandem Hairpin Pyrrole-Imidazole Polyamides.2008
- Author(s)
  Sasaki, S., Bando, T., Minoshima, M., Shinohara, K., Sugiyama, H.
- Journal Title
  
  Chem.Eur.J. 18
  
  Pages: 864-870
- Data Source
  KAKENHI-PROJECT-19205023
[Journal Article] Pyrrole-imidazole hairpin polyamides with high affinity at 5'-CGCG-3' DNA sequence ; Influence of cytosine methylation on binding2008
- Author(s)
  Sugiyama H.; Bando, T.
- Journal Title
  
  Nucleic. Acids. Res 36
  
  Pages: 2889-28941
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Perylene-Conjugated Pyrrole Polyamide as a Sequence-Specific Fluorescent Probe2008
- Author(s)
  Bando, T., Sugiyama, H
- Journal Title
  
  Bioorganic & Medicinal Chemistry 16
  
  Pages: 9741-9744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611008
[Journal Article] Requirement of β-Alanine Components in Sequence-Specific DNA Alkylation by Pyrrole-Imidazole Conjugates with Seven-Base Pair Recognition.2008
- Author(s)
  Bando, T., Minoshima, M., Kashiwazaki, G., Shinohara, K., Sasaki, S., Fujimoto, J., Ohtsuki, A., Murakami, M., Nakazono, S., Sugiyama, H.
- Journal Title
  
  Bioorg.Med.Chem. 16
  
  Pages: 2286-2291
- Data Source
  KAKENHI-PROJECT-19205023
[Journal Article] Sequence-Specific Alkylation by Y-shaped and Tandem Hairpin Pyrrole-Imidazole Polyamides.2008
- Author(s)
  Sasaki, S.; Bando, T.; Minoshima, M.; Shinohara, K.; Sugiyama, H.
- Journal Title
  
  Chem. Eur. J. 14
  
  Pages: 864-870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Development of Pyrrole-Imidazole Polyamide for Specific Regulation of Human Aurora Kinase A and B Gene Expression.2008
- Author(s)
  Takahashi, T.; Asami, Y.; Kitamura, E.; Suzuki, T.; Wang, X.; Igarashi, J.; Morohashi, A.; Shinojima, Y.; Kanou, H.; Saito, K.; Takasu, T.; Nagase, H.; Harada, Y.; Kuroda, K.; Watanabe, T.; Kumamoto, S.; Aoyama, T.; Matsumoto, Y.; Bando, T.; Sugiyama, H.; Yoshida-Noro, C.; Fukuda, N.; Hayashi N.
- Journal Title
  
  Chem. Biol. 15
  
  Pages: 829-841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] DNA Alkylation by Pyrrole-Imidazole seco-CBI Conjugates with an Indole Linker: Sequence-Specific DNA Alkylation with Ten-Base-Pair Recognition through Hetelodimer Formation.2007
- Author(s)
  Minoshima, M.; Bando, T.; Sasaki, S.; Shinohara, K.; Shimizu, T.; Fujimoto, J.; Sugiyama, H.
- Journal Title
  
  J. Am. Chem. Soc. 129
  
  Pages: 5384-5390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Detection of CAG Repeat DNA Sequences by Pyrene- Functionalized Pyrrole-Imidazole Polyamides2007
- Author(s)
  Bando, T.; Sugiyama H.
- Journal Title
  
  Bioorg. Med. Chem. 15
  
  Pages: 6937-6942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18651107
[Journal Article] DNA Alkylation by Pyrrole-Imidazole seco-CBI Conjugates with an Indole Linker: Sequence-Specific DNA Alkylation2007
- Author(s)
  Sugiyama H.; Bando, T.
- Journal Title
  
  J. Am. Chem. Soc. 129
  
  Pages: 5384-5390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] DNA Alkylation by Pyrroie-Imidazoie seco-CBI Conjugates with an Indole Linker: Sequence-Specific DNA Alkylation with Ten-Base-Pair Recognition throug Hetelodimer Formation2007
- Author(s)
  Sugiyama H.; Bando, T.
- Journal Title
  
  J. Am. Chem. Soc. 129
  
  Pages: 5384-5390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19205023
[Journal Article] DNA Alkylation by Pyrrole-Imidazole seco-CBI Con jugates with an Indole Linker: Sequence-Specific DNA AIkylation2007
- Author(s)
  Bando, T.; Sugiyama H.
- Journal Title
  
  J. Am. Chem. Soc. 129
  
  Pages: 5384-5390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18651107
[Journal Article] Detection of CAG Repeat DNA Sequences by Pyrene-Functionalized Pyrrole-Imidazole Polyamides.2007
- Author(s)
  Bando, T.;Fujimoto, J.; Minoshima, M.; Shinohara, K.; Sasaki, S.; Kashiwazaki, G.; Mizumura, M.; Sugiyama, H.
- Journal Title
  
  Bioorg. Med. Chem. 15
  
  Pages: 6937-6942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] DNA Alkylation by Pyrrole-Imidazole seco-CBI Conjugates with an Indole Linker : Sequence-Specific DNA Alkylation with Ten-Base-Pair Recognition throug Hetelodimer Formation.2007
- Author(s)
  Minoshima, M., Bando, T., Sasaki, S., Shinohara, K., Shimizu, T., Fujimoto, J., Sugiyama, H.
- Journal Title
  
  J.Am.Chem.Soc. 129
  
  Pages: 5384-5390
- Data Source
  KAKENHI-PROJECT-19205023
[Journal Article] Development of Gene Silencing Pyrrole-Imidazole Polyamide Targeting the TGF-β1 Promoter for Treatment of Progressive Renal Diseases.2006
- Author(s)
  Sugiyama H., Bando, T., N.Fukuda
- Journal Title
  
  J.Am.Soc.Nephr. 17・Feb
  
  Pages: 422-432
- NAID
  10024923283
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Discrimination of Hairpin Polyamides with anα-Substituted-γ-Aminobutyric Acid as a 5'-TG-3' Reader in DNA Minor Groove.2006
- Author(s)
  Zhang, W.; Bando, T.; Sugiyama, H.
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 8766-8776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Synthesis and Biological Properties of Sequence-Specific DNA-Alkylatiog Pyrrole-Imidazole Polyamides2006
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  Acc.Chem.Res. 39・12
  
  Pages: 935-944
- Data Source
  KAKENHI-PROJECT-18651107
[Journal Article] Alkylation of Template Strand of Coding Region Causes Effective Gene Silencing.2006
- Author(s)
  Shinohara, K.; Sasaki, S.; Minoshima, M.; Bando, T.; Sugiyama, H.
- Journal Title
  
  Nucleic Acids Res. 34
  
  Pages: 1189-1195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Efficient DNA Alkylation by a Pyrrole-Imidazole CBI Conjugate with an Indole Linker: Sequence Specific Alkylation with Nine-Base-Pair Recognition.2006
- Author(s)
  Bando, T.; Sasaki, S.; Minoshima, M.; Dohno, C.; Shinohara, K.; Narita, A.; Sugiyama, H.
- Journal Title
  
  Bioconjugate Chem. 17
  
  Pages: 715-720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Antitumor Activity of Sequence-Specific Alkylating Agents: Pyrrole-Imidazole CBI Conjugates with Indole Linker.2006
- Author(s)
  Shinohara, K.; Bando, T.; Sasaki, S.; Sakakibara, Y.; Minoshima, M.; Sugiyama, H.
- Journal Title
  
  Cancer Science. 97
  
  Pages: 219-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Efficient DNA Alkylation by a Pyrrole-Imidazole CBI Conjugate with an Indole Linker : Sequence Specific Alylation with Nine-Base-Pair Recognition2006
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  Bioconjugate Chem. 17・3
  
  Pages: 715-720
- Data Source
  KAKENHI-PROJECT-18651107
[Journal Article] Development of Gene Silencing Pyrrole-Imidazole Polyamide Targeting the TGF-β1 Promoter for Treatment of Progressive Renal Diseases.2006
- Author(s)
  Matsuda, H.; Fukuda, N.; Ueno, T.; Tahira, Y.; Ayame, H.; Zhang, W.; Bando, T.; Sugiyama, H.; Saito, S.; Matsumoto, K.; Mugishima, H.; Serie, K.
- Journal Title
  
  J. Am. Soc. Nephr. 17
  
  Pages: 422-432
- NAID
  10024923283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Development of Gene Silencing Pyrrole-Imidazole Polyamide Targeting the TGF-β1 Promoter for Treatment of Progressive Renal Diseases.2006
- Author(s)
  Bando, T., Sugiyama H., N.Fukuda
- Journal Title
  
  J.Am.Soc.Nephr. 17・Feb
  
  Pages: 422-432
- NAID
  10024923283
- Data Source
  KAKENHI-PROJECT-16681019
[Journal Article] Sequence-Specific Alkylation of Double-Strand Human Telomere Repeat Sequence by Pyrrole-Imidazole Polyamides with Indole Linkers.2006
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  J.Am.Chem.Soc. 128・37
  
  Pages: 12162-12168
- Data Source
  KAKENHI-PROJECT-16681019
[Journal Article] Discrimination Of Hairpin Polyamides witn an Alpna-Substituted-Gamma-Aminobutyric Acid as a 5'-TG-3' Reader in DNA Minor Groove2006
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  J.Am.Chem.Soc. 128・27
  
  Pages: 8766-8776
- Data Source
  KAKENHI-PROJECT-18651107
[Journal Article] Synthesis and Biological Properties of Sequence-Specific DNA-Alkylating Pyrrole-Imidazole Polyamides2006
- Author(s)
  Sugiyama H., Bando, T.
- Journal Title
  
  Acc.Chem.Res. 39・12
  
  Pages: 935-944
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Discrimination of Hairpin Polyamides with an Alpha-Substituted-Gamma-Aminobutyric Acid as a 5'-TG-3' Reader in DNA Minor Groove.2006
- Author(s)
  Sugiyama H., Bando, T.
- Journal Title
  
  J.Am.Chem.Soc. 128・27
  
  Pages: 8766-8776
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Alkylation of template strand of coding region causes effective gene silencing.2006
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  Nucleic Acids Res. 34・4
  
  Pages: 1189-1195
- Data Source
  KAKENHI-PROJECT-18651107
[Journal Article] Antitumor Activity of sequence-specific Alkylating Agents : Pyrrole-imidazole CBI conjugates with Indole linker2006
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  Cancer Science 97・3
  
  Pages: 219-225
- Data Source
  KAKENHI-PROJECT-18651107
[Journal Article] Antitumor Activity of Sequence-specific Alkylating Agents : Pyrrole-imidazole CBI conjugates with Indole linker2006
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  Cancer Science 97・3
  
  Pages: 219-225
- Data Source
  KAKENHI-PROJECT-16681019
[Journal Article] Efficient DNA Alkylation by a Pyrrole-Imidazole CBI Conjugate with an Indole Linker : Sequence Specific Alkylation with Nine-Base-Pair Recognition2006
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  Bioconjugate Chem. 17・3
  
  Pages: 715-720
- Data Source
  KAKENHI-PROJECT-16681019
[Journal Article] Efficient DNA Alkylation by a Pyrrole-Imidazole CBI Conjugate with an Indole Linker : Sequence Specific Alkylation with Nine-Base-Pair Recognition.2006
- Author(s)
  Sugiyama H., Bando, T.
- Journal Title
  
  Bioconjugate Chem. 17・3
  
  Pages: 715-720
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Discrimination or Hairpin Polyamides with an Aipha-Substituted-Gamma-Aminobutyric Acid as a 5'-TG-3' Reader in DNA Minor Grooye2006
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  J.Am.Chem.Soc. 128・27
  
  Pages: 8766-8776
- Data Source
  KAKENHI-PROJECT-16681019
[Journal Article] Sequence-Specific Alkylation of Double-Strand Human Telomere Repeat Sequence by Pyrrole-Imidazole Polyamides with Indole Linkers.2006
- Author(s)
  Sugiyama H., Bando, T.
- Journal Title
  
  J.Am.Chem.Soc. 128・37
  
  Pages: 12162-12168
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Sequence-Specific Alkylation of Double-Strand Human Telomere Repeat Sequence by Pyrrole-Imidazole Polyamides with Indole Linkers.2006
- Author(s)
  Sasaki, S.; Bando, T.; Minoshima, M.; Shimizu, T.; Shinohara, K.; Takaoka, T.; Sugiyama, H.
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 12162-12168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Sequence-Specific AlKylation of Double-Strand Human Telomere Repeat Sequence by Pyrrole-Imidazole Polyamides with Indole Linkers.2006
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  J.Am.Chem.Soc. 128・37
  
  Pages: 12162-12168
- Data Source
  KAKENHI-PROJECT-18651107
[Journal Article] Synthesis and Biological Properties of Sequence-Specific DNA-Alkylating Pyrrole-Imidazole Polyamides2006
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  Acc.Chem.Res. 39・12
  
  Pages: 935-944
- Data Source
  KAKENHI-PROJECT-16681019
[Journal Article] Alkylation of template strand of coding region causes effective gene silencing.2006
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  Nucleic Acids Res. 34・4
  
  Pages: 1189-1195
- Data Source
  KAKENHI-PROJECT-16681019
[Journal Article] Synthetic Pyrrole-Imidazole Polyamide Inhibits Expression of the Human Transforming Growth Factor-β1 Gene.2005
- Author(s)
  Sugiyama H., Bando, T., N.Fukuda
- Journal Title
  
  J.Pharmacol.Exp.Ther. 315・2
  
  Pages: 571-575
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] The Possibility of Sequence-specific DNA Alkylation toward Therapeutic Drugs2005
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  Pharm.Regul.Sci. 36・1
  
  Pages: 1-12
- Data Source
  KAKENHI-PROJECT-16681019
[Journal Article] Synthetic Pyrrole-Imidazole Polyamide Inhibits Expression of the Human Transforming Growth Factor-β1 Gene.2005
- Author(s)
  Bando, T., Sugiyama H., N.Fukuda
- Journal Title
  
  J.Pharmacol.Exp.Ther. 315・2
  
  Pages: 571-575
- Data Source
  KAKENHI-PROJECT-16681019
[Journal Article] Specific Adenine Alkylation by Pyrrole-Imidazole CBI Conjugates2005
- Author(s)
  Sugiyama H., Bando, T.
- Journal Title
  
  J.Am.Chem.Soc. 127・40
  
  Pages: 13890-13895
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Synthetic Pyrrole-Imidazole Polyamide Inhibits Expression of the Human Transforming Growth Factor-β1 Gene.2005
- Author(s)
  Lai, Y. -M.; Fukuda, N.; Ueno, T.; Kishioka, H.; Matsuda, H.; Saito, S.; Matsumoto, K.; Ayame, H.; Bando, T.; Sugiyama, H.; Mugishima, H.; Kim, S. -J.
- Journal Title
  
  J. Pharmacol. Exp. Ther. 315
  
  Pages: 571-575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] The Chemical Biology That Controls DNA Function arid Structure2005
- Author(s)
  Sugiyama H., Bando, T.
- Journal Title
  
  有機合成化学協会誌 63・10
  
  Pages: 1016-1027
- Data Source
  KAKENHI-PROJECT-17201043
[Journal Article] The Chemical Biology That Controls DNA Function and Structure2005
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  有機合成化学協会誌 63・10
  
  Pages: 1016-1027
- NAID
  130000928679
- Data Source
  KAKENHI-PROJECT-16681019
[Journal Article] Specific Adenine Alkylation by Pyrrole-Imidazole CBI Conjugates.2005
- Author(s)
  Bando, T.; Narita, A.; Sasaki, S.; Sugiyama, H.
- Journal Title
  
  J. Am. Chem. Soc. 127
  
  Pages: 13890-13895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] The Chemical Biology That Controls DNA Function and Structure2005
- Author(s)
  Sugiyama H., Bando, T.
- Journal Title
  
  有機合成化学協会誌 63・10
  
  Pages: 1016-1027
- NAID
  130000928679
- Data Source
  KAKENHI-PROJECT-17016033
[Journal Article] Specific Adenine Alkylation by Pyrrole-Imidazole CBI Conjugates2005
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  J.Am.Chem.Soc. 127・40
  
  Pages: 13890-13895
- Data Source
  KAKENHI-PROJECT-16681019
[Journal Article] C-H to N Substitution Dramatically Alters the Sequence-Specific DNA Alkylation, Cytotoxicity, and Expression of Human Cancer Cell Lines2004
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  J.Am.Chem.Soc. 126・11
  
  Pages: 3406-3407
- Data Source
  KAKENHI-PROJECT-13218046
[Journal Article] C-H to N Substitution Dramatically Alters the Sequence-Specific DNA Alkylation, Cytotoxicity, and Expression of Human Cancer Cell Lines2004
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  J.Am.Chem.Soc. 126・11
  
  Pages: 3406-3407
- Data Source
  KAKENHI-PROJECT-16681019
[Journal Article] Enantioselective DNA Alkylation by a Pyrrole-Imidazole S-CBI Conjugate2004
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  J.Am.Chem.Soc. 126・29
  
  Pages: 8948-8955
- Data Source
  KAKENHI-PROJECT-16681019
[Journal Article] Sequence-Specific Gene Silencing in Mammalian Cells by Alkylating Pyrrole-imidazole Polyamides2004
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  J.Am.Chem.Soc. 126・16
  
  Pages: 5113-5118
- Data Source
  KAKENHI-PROJECT-13218046
[Journal Article] Enantioselective DNA Alkylation by a Pyrrole-Imidazole S-CBI Conjugate2004
- Author(s)
  Bando, T., Sugiyama, H.
- Journal Title
  
  J.Am.Chem.Soc. 126・29
  
  Pages: 8948-8955
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15201046
[Journal Article] Enantioselective DNA Alkylation by a Pyrrole-Imidazole S-CBI Conjugate2004
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  J.Am.Chem.Soc. 126・29
  
  Pages: 8948-8955
- Data Source
  KAKENHI-PROJECT-13218046
[Journal Article] Enantioselective DNA Alkylation by a Pyrrole-Imidazole S-CBI Conjugate2004
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  J.Am.Chem.Soc. 126・29
  
  Pages: 8948-8955
- Data Source
  KAKENHI-PROJECT-15201046
[Journal Article] Sequence-Specific Gene Silencing in Mammalian Cells by Alkylating Pyrrole-imidazole Polyamides2004
- Author(s)
  Bando, T., Sugiyama H.
- Journal Title
  
  J.Am.Chem.Soc. 126・16
  
  Pages: 5113-5118
- Data Source
  KAKENHI-PROJECT-16681019
[Journal Article] Synthetic small molecules for epigenetic activation of pluripotent genes in mouse embryonic fibroblasts
- Author(s)
  Pandian GN, Shinohara K, Ohtsuki A, Nakano Y, Minoshima M, Bando T, Nagase H, Yamada Y, Watanabe A, Terada N, Sato S, Morinaga H and Sugiyama H
- Journal Title
  
  ChemBioChem
  
  Volume: 12(18) Pages: 2822-2
- Data Source
  KAKENHI-PROJECT-23300344
[Patent] ドライバーオンコジーンの遺伝子変異を標的にアルキル化する新規アルキル化剤2016
- Inventor(s)
  永瀬浩喜, 杉山弘, 板東俊和
- Industrial Property Rights Holder
  千葉県, 国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-05-10
- Overseas
- Data Source
  KAKENHI-PROJECT-24225005
[Patent] ドライバーオンコジーンの遺伝子変異を標的にアルキル化する新規アルキル化剤2016
- Inventor(s)
  永瀬浩喜, 杉山弘, 板東俊和
- Industrial Property Rights Holder
  千葉県, 国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-04-07
- Overseas
- Data Source
  KAKENHI-PROJECT-24225005
[Patent] 特定遺伝子の発現を活性化するＣＴＢ－ＰＩポリアミドコンジュゲート2015
- Inventor(s)
  杉山　弘, 板東俊和
- Industrial Property Rights Holder
  京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-025715
- Filing Date
  2015-02-12
- Data Source
  KAKENHI-PROJECT-24310155
[Patent] 特定遺伝子の発現を活性化するＣＴＢ－ＰＩポリアミドコンジュゲート2015
- Inventor(s)
  杉山　弘板東俊和
- Industrial Property Rights Holder
  京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-025715
- Filing Date
  2015-02-12
- Data Source
  KAKENHI-PROJECT-24225005
[Patent] ドライバーオンコジーンの遺伝子変異を標的にアルキル化する新規アルキル化剤2013
- Inventor(s)
  永瀬浩喜, 杉山弘, 板東俊和
- Industrial Property Rights Holder
  千葉県および京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-214044
- Filing Date
  2013-10-11
- Data Source
  KAKENHI-PROJECT-23300344
[Patent] ドライバーオンコジーンの遺伝子変異を標的にアルキル化する新規アルキル化剤2013
- Inventor(s)
  永瀬浩喜、杉山弘、板東俊和
- Industrial Property Rights Holder
  千葉県
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-214044
- Filing Date
  2013-10-11
- Data Source
  KAKENHI-PROJECT-23300344
[Patent] 標的遺伝子特異的ヒストン修飾制御剤2011
- Inventor(s)
  永瀬浩喜, 杉山弘, 鈴木司, 板東俊和, 木村真, 大朏彰道
- Industrial Property Rights Holder
  日本大学
- Industrial Property Rights Type
  特許
- Acquisition Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-23300344
[Patent] 標的遺伝子特異的ヒストン修飾制御剤2008
- Inventor(s)
  永瀬浩喜, 板東俊和
- Industrial Property Rights Holder
  学校法人日本大学
- Industrial Property Number
  2008-172795
- Filing Date
  2008-07-01
- Data Source
  KAKENHI-PROJECT-20611008
[Presentation] Synthesis and Evaluation of Pyrrole－Imidazole Polyamide Conjugates with Pyridostatin Analogues2023
- Author(s)
  大賀充陽、板東俊和、杉山弘
- Organizer
  第50回核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05353
[Presentation] Development and evaluation of pyrrole-imidazole polyamide targeting CCTG/CAGG repeats2023
- Author(s)
  小林かれん、畑中淳之介、橋谷かおり、杉山弘、板東俊和
- Organizer
  生体機能関連化学部会若手の会
- Data Source
  KAKENHI-PROJECT-22K05353
[Presentation] Development of pyrrole-imidazole polyamides that target CCTG/CAGG repeat DNA in Myotonic Dystrophy Type 22023
- Author(s)
  小林かれん、畑中淳之介、橋谷かおり、杉山弘、板東俊和
- Organizer
  第50回核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05353
[Presentation] Development of a Novel Synthetic Ligand to Visualize the Mitochondrial G-quadruplex2023
- Author(s)
  野泉燎平、佐々木大輔、大賀充陽、板東俊和、杉山弘
- Organizer
  第50回核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05353
[Presentation] Synthetic transcriptional activator of genes associated with retina in human dermal fibroblasts2015
- Author(s)
  Junetha Syed Jabarulla, Anadhakumar Chandran, Ganesh Namasivayam Pandian, Junichi Taniguchi, Shinsuke Sato, Kaori Hashiya, Gengo Kashiwazaki, Toshikazu Bando, Hirosi Sugiyama
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015 (PACIFICHEM 2015)
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24225005
[Presentation] 小分子化合物によるOct3/4遺伝子発現の活性化2015
- Author(s)
  佐藤慎祐、朝光世煌、Thangavel Vaijayanthi, Namasivayam Ganesh Pandian、谷口純一、Junetha Syed Jabarulla, Anandhakumar Chandran, Tingting Zou, Yulei Wei、橋谷かおり、板東俊和、杉山弘
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会（BMB2015）
- Place of Presentation
  神戸市
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-24225005
[Presentation] Identification of genomic targets of DNA binding small molecules using next generation sequencing2015
- Author(s)
  Anandhakumar Chandran, Rhys Taylor, Junetha Syed Jabarulla, Shinsuke Sato, Gengo Kashiwazaki, Toshikazu Bando, Hiroshi Sugiyama
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015 (PACIFICHEM 2015)
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24225005
[Presentation] 特定遺伝子の発現を制御するPI-ポリアミドの開発2015
- Author(s)
  板東俊和
- Organizer
  日本薬学会第135年会　シンポジウム：中分子創薬研究のフロンティア
- Place of Presentation
  神戸学院大学
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-24310155
[Presentation] エピジェネティック活性を有する小分子化合物を用いた遺伝子発現制御2014
- Author(s)
  谷口純一、Namasivayam Ganesh Pandian、Junetha Syed、佐藤慎祐、Le Han、板東俊和、杉山弘
- Organizer
  日本ケミカルバイオロジー学会第9回年会
- Place of Presentation
  豊中市、大阪大学
- Year and Date
  2014-06-13
- Data Source
  KAKENHI-PROJECT-24225005
[Presentation] Sequence selective electron injection into the DNA using pyrrole imidazole polyamide: a novel approach for determining sequence selectivity2014
- Author(s)
  Abhijit Saha、橋谷文貴、木崎誠一朗、Yue Li、板東俊和、杉山　弘
- Organizer
  第36回日本光医学・光生物学会
- Place of Presentation
  豊中市、大阪大学
- Year and Date
  2014-07-26
- Data Source
  KAKENHI-PROJECT-24225005
[Presentation] 変異型KRAS を標的とした配列特異的アルキル化剤による腫瘍細胞の増殖抑制2013
- Author(s)
  平岡桐子, 井上貴博, 養田裕行, 杉本博一, 篠原憲一, 渡部隆義, 越川信子, 板東俊和, 杉山弘, 尾崎俊文, 永瀬浩喜
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23300344
[Presentation] DNA塩基配列特異性を有する機能性Py-Imポリアミドの開発2013
- Author(s)
  板東俊和
- Organizer
  第２３回アンチセンスシンポジウム
- Place of Presentation
  徳島大学
- Data Source
  KAKENHI-PROJECT-24310155
[Presentation] 変異型KRASを標的とした塩基配列特異的アルキル化剤によるマウス移植ヒト大腸癌の増殖抑制2013
- Author(s)
  ・井上貴博, 平岡桐子, 養田裕行, 杉本博一, 篠原憲一, 渡部隆義, 越川信子, 尾崎俊文, 永瀬浩喜, 坂東俊和, 杉山弘
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23300344
[Presentation] ヒトテロメア配列に特異的に結合するタンデム型ピロール・イミダゾールポリアミドの合成2013
- Author(s)
  河本佑介, 板東俊和, et al
- Organizer
  日本化学会第93春季年会(2013)
- Place of Presentation
  立命館大学びわこくさつキャンパス
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-24310155
[Presentation] 変異型KRAS を標的とした塩基配列特異的アルキル化剤によるマウス移植ヒト大腸癌の増殖抑制2013
- Author(s)
  井上貴博, 平岡桐子, 養田裕行, 杉本博一, 篠原憲一, 渡部隆義, 越川信子, 板東俊和, 杉山弘, 尾崎俊文, 永瀬浩喜
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23300344
[Presentation] 変異型KRASを標的とした塩基配列特異的アルキル化剤による腫瘍細胞の増殖抑制2013
- Author(s)
  ・平岡桐子, 井上貴博, 養田裕行, 杉本博一, 篠原憲一, 渡部隆義, 越川信子, 尾崎俊文, 永瀬浩喜, 板東俊和, 杉山弘
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23300344
[Presentation] ゲノム配列特異的ヒストン修飾変更:がん化メカニズムの探索と治療への応用2012
- Author(s)
  永瀬浩喜、渡部隆義、越川信子、板東俊和、杉山弘
- Organizer
  第７１回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23300344
[Presentation] 小分子化合物によるMEFでの多能性細胞誘導遺伝子のエピジェネティックな活性化2012
- Author(s)
  永瀬浩喜、渡部隆博、越川信子、井上貴博、平岡桐子、板東俊和、杉山弘
- Organizer
  第２６回モロシヌス研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23300344
[Presentation] Target epigenetic regulation at a specific genomic region to induce stem cell like phenotype in neuroblastoma cells.2012
- Author(s)
  Nagase H , Watanabe T, Koshikawa N, Bando T, Sugiyama H.
- Organizer
  44th Congress of the International Society of Paediatric Oncology (SIOP)
- Place of Presentation
  London UK
- Data Source
  KAKENHI-PROJECT-23300344
[Presentation] Target epigenetic regulation at a specific genomic region to induce stem cell like phenotype in nenroblastoma cells2011
- Author(s)
  Hiroki Nagase, Takayoshi Watanabe, Nobuko Koshikawa, Toshikazu Bando, Hiroshi Sugiyama
- Organizer
  The 43^<rd> SIOP meeting第43回国際小児がん学会
- Place of Presentation
  Auckland, New Zealand
- Data Source
  KAKENHI-PROJECT-23300344
[Presentation] 配列特異的アルキル化を可能にする光切断リンカーを導入したPy-Imポリアミド-CBIコンジュゲート2010
- Author(s)
  朴昭映、板東俊和、杉山弘
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20611008
[Presentation] Recognition of Specific DNA Sequences by Pyrrole-Imidazole Polyamides2010
- Author(s)
  板東俊和
- Organizer
  2010International Chemical Congress of Pacific Basin Societies(PACIFICHEM)
- Place of Presentation
  Hawaii, USA, December
- Data Source
  KAKENHI-PROJECT-20611008
[Presentation] PIポリアミド-SAHAコンジュゲートライブラリによる細胞のリプログラミング2010
- Author(s)
  篠原憲一、板東俊和、杉山弘
- Organizer
  日本ケミカルバイオロジー学会第5回年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20611008
[Presentation] Recognition of Specific DNA Sequences by Pyrrole-Imidazole Polyamides2010
- Author(s)
  T.Bando
- Organizer
  2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM)
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-19205023
[Presentation] Recognition of Specific DNA Sequences by Pyrrole-Imidazole Polyamides2010
- Author(s)
  Bando, T.
- Organizer
  2010 International Chemical Congress of Pacific Basin Societies(PACIFICHEM)
- Place of Presentation
  Hawaii
- Data Source
  KAKENHI-PROJECT-20611008
[Presentation] 塩基配列特異的アルキル化能を有する機能性PIポリアミド設計2009
- Author(s)
  板東俊和, 杉山弘
- Organizer
  第28回メディシナルケミストリーシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17016033
[Presentation] PIポリアミドコンジュゲートによる配列特異的DNAアルキル化反応2009
- Author(s)
  板東俊和、蓑島維文、篠原憲一、杉山弘
- Organizer
  第12回がん分子標的治療学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-20611008
[Presentation] 塩基配列特異的アルキル化能を有する機能性PIポリアミド設計2009
- Author(s)
  板東俊和、杉山弘
- Organizer
  第28回メディシナルケミストリーシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20611008
[Presentation] 機能性PIポリアミドの合成とその機能評価2009
- Author(s)
  板東俊和、蓑島維文、柏崎玄伍、西島茂樹、杉山弘
- Organizer
  日本ケミカルバイオロジー学会第4回年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20611008
[Presentation] 機能性PIポリアミドの合成とその機能評価2009
- Author(s)
  板東俊和
- Organizer
  日本ケミカルバイオロジー学会第4回年会
- Place of Presentation
  神戸市産業振興センター
- Data Source
  KAKENHI-PROJECT-20611008
[Presentation] PIポリアミドコンジュゲートによる配列特異的DNAアルキル化反応2009
- Author(s)
  板東俊和, 蓑島維文, 篠原・憲一, 杉山弘
- Organizer
  第12回がん分子標的治療学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-19205023
[Presentation] DNAの配列特異的アルキル化と生物化学的応用2009
- Author(s)
  蓑島維文、板東俊和、篠原憲一、杉山弘
- Organizer
  日本化学会第89春季年会(2009)
- Place of Presentation
  船橋市
- Data Source
  KAKENHI-PROJECT-20611008
[Presentation] 機能性ピロール-イミダゾールポリアミドによる特異的DNA塩基配列の検出2008
- Author(s)
  板東俊和
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-19205023
[Presentation] テロメアを標的とするピロール-イミダゾールポリアミド2008
- Author(s)
  篠原憲一、板東俊和、杉山弘
- Organizer
  第12回がん分子標的治療研究会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20710164
[Presentation] 特定DNA塩基配列を標的とする機能性ポリアミドの開発2008
- Author(s)
  板東俊和, 杉山弘
- Organizer
  薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17016033
[Presentation] テロメアを標的とするピロール-イミダゾールポリアミド2008
- Author(s)
  篠原憲一、蓑島維文、板東俊和、杉山弘
- Organizer
  第12回がん分子標的治療研究会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20611008
[Presentation] 機能性PIポリアミドによる特異的DNA塩基配列確認2008
- Author(s)
  板東俊和
- Organizer
  学術フロンティア報告会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20611008
[Presentation] 機能性ピロールーイミダゾールポリアミドによる特異的DNA塩基配列の検出2008
- Author(s)
  板東俊和
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜市
- Data Source
  KAKENHI-PROJECT-20611008
[Presentation] 特定DNA配列を標的とする機能性ピロールーイミダゾールポリアミドの開発2007
- Author(s)
  板東俊和
- Organizer
  第11回がん分子標的治療研究会総会
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2007-07-06
- Data Source
  KAKENHI-PROJECT-18651107
[Presentation] dna配列を標的とするアルキル化ピロール-イミダゾールポリアミドの開発2006
- Author(s)
  板東俊和, 杉山弘
- Organizer
  第10回がん分子標的治療研究会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17016033
[Presentation] Therapeutic gene modulation using DNA-based transcriptional activators
- Author(s)
  Ganesh N. Pandian, J. Taniguchi, S. Sato, L. Han, S. Junetha, T. Bando, and H. Sugiyama
- Organizer
  Asian International Symposium -Medicinal Chemistry in The 95th Annual Meeting of The Chemical Society of Japan
- Place of Presentation
  Funabashi, Chiba, Japan
- Year and Date
  2015-03-26 – 2015-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-26670055
[Presentation] Alteration of global gene expression in human somatic cells using DNA-based epigenetic switches
- Author(s)
  Ganesh N. Pandian, J. Taniguchi, S. Junetha, S. Sato, L. Han, A. Saha, C. Anandhakumar, T. Bando, and H. Sugiyama
- Organizer
  ISSCR Regional Forum - Global control of stem cells
- Place of Presentation
  Biopolis, Singapore
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-26670055

1. SUGIYAMA Hiroshi (50183843)

# of Collaborated Projects: 11 results

# of Collaborated Products: 102 results
2. NAMASIVAYAN Ganesh Pandian (20625446)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. SHINOHARA Kenichi (70378561)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
4. NAGASE Hiroki (90322073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
5. Suzuki Yuki (50636066)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 渡部隆義 (60526060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. 遠藤政幸 (70335389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. ARIVAZHAGAN RAJENDRAN (90723122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SATO Shinsuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
10. HIDAKA Kumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. EMURA Tomoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HASHIYA Kaori

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
13. KAWAMOTO Yusuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. ASAMITSU Sefan

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. TANIGUCHI Junichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
16. Taylor Rhys D.

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. A. RAJENDRAN

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
18. 伊川正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 篠原隆司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 前島一博

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
21. 矢吹悌

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 齋藤都暁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

BANDO Toshikazu 板東 俊和

坂東 俊和 バンドウ トシカズ

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DNA配列や構造を認識する結合性リガンドの開発Principal Investigator

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The development of novel functional Py-Im polyamide conjugates for sequence-specific gene regulationPrincipal Investigator

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The development of the functional polyamides to regulate specific DNA-protein structurePrincipal Investigator

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生物学的評価を指向したアルキル化ポリアミドの合成研究Principal Investigator

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反応性Py-Imポリアミドによる遺伝子機能解析法の確立Principal Investigator

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BANDO Toshikazu 板東俊和

坂東俊和バンドウトシカズ