MIZUNO Makoto 水野誠

… Alternative Names

水野誠ミズノマコト

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Researcher Number	20345515
External Links
Affiliation (based on the past Project Information) *help	2012 – 2018: 愛知県心身障害者コロニー発達障害研究所, 神経制御学部, 主任研究員 2011: 新潟大学, 脳研究所, 特任准教授 2008 – 2010: Niigata University, 超域研究機構, 准教授 2006: 新潟大学, 脳研究所, 助教授 2005: 新潟大学, 超域研究機構, 助教授 2002 – 2004: 新潟大学, 脳研究所, 助手
Review Section/Research Field	Principal Investigator General pharmacology / Basic Section 48030:Pharmacology-related / Pharmacology in pharmacy / Pathological medical chemistry Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 発達障害 / ドパミン / 認知 / 栄養因子 / 大脳皮質 / 炎症 / 社会性行動 / 行動解析 / 脳内炎症 / 活性酵素 … More / 統合失調症 / 活性酸素 / 情動 / 脳内注入 / 行動学 / シクロオキシゲナーゼ / 驚愕反応 / 認知機能 / プロスタグランジン … More Except Principal Investigator 分子診断 / DNAチップ / 精神疾患 / eEF2キナーゼ / eEF2 / 翻訳伸展 / ニューロン / p70S6K / 4EBP / BDNF / 局所的蛋白合成 / 海馬 / 空間学習 / 翻訳調節 / mTOR / 遺伝子プロファイル / マイクロアレイ / 遺伝子発現 / 単核球 / 総合失調症 / モデル動物 / 神経発達 / 脳栄養因子 / ストレス / 認知行動 / 上皮成長因子 / 統合失調症 / 栄養因子 / 脳発達 / ドパミン / サイトカイン Less

脳内炎症による行動異常に対する大脳皮質神経細胞移動の関与Principal Investigator
- Principal Investigator
  
  水野誠
- Project Period (FY)
  2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Institute for Developmental Research, Aichi Human Service Center
Analysis of cognitive behavioral disorders induced by neurotrophic factor in developmental dopaminergic neuronPrincipal Investigator
- Principal Investigator
  
  MIZUNO MAKOTO
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Institute for Developmental Research, Aichi Human Service Center
Involvement of prostaglandins in cognitive function induced by brain inflammationPrincipal Investigator
- Principal Investigator
  
  MAKOTO MIZUNO
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Institute for Developmental Research, Aichi Human Service Center
Antipsychotic potential of antioxidative agents in animal model for schizophreniaPrincipal Investigator
- Principal Investigator
  
  MIZUNO Makoto
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Niigata University
Regulation of dopaminergic neuron development by trophic factor and neurofunction disorderPrincipal Investigator
- Principal Investigator
  
  MIZUNO Makoto
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Niigata University
局所的mRNA翻訳マシナリーの活性化と脳高次機能
- Principal Investigator
  
  武井延之
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
精神疾患の遺伝子発現データベースの構築と分子病態解析
- Principal Investigator
  
  那波宏之
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
プロスタグランジンの認知・記憶に対する影響とその生理メカニズムPrincipal Investigator
- Principal Investigator
  
  水野誠
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Niigata University
精神疾患の遺伝子発現データベースの構築と分子病態解析
- Principal Investigator
  
  那波宏之
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
脳内サイトカインによる中枢神経機能の制御メカニズム:分子から精神活動へ
- Principal Investigator
  
  那波宏之
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Niigata University

All 2018 2017 2015 2014 2013 2012 2011 2010 2009 2008 2004 Other

All Journal Article Presentation

[Journal Article] Rho family GTPases, Rac and Cdc42 control the localization of neonatal dentate granule cells during brain development.2018
- Author(s)
  Ito H, Morishita R, Mizuno M, Tabata H, Nagata KI.
- Journal Title
  
  Hippocampus.
  
  Volume: Nov Pages: 2-2
- Data Source
  KAKENHI-PROJECT-15K07989
[Journal Article] Biochemical and Morphological Characterization of a Guanine Nucleotide Exchange Factor ARHGEF9 in Mouse Tissues.2018
- Author(s)
  Ibaraki K, Mizuno M, Aoki H, Niwa A, Iwamoto I, Hara A, Tabata H, Ito H, Nagata KI.
- Journal Title
  
  Acta Histochem Cytochem
  
  Volume: 51 Pages: 119-128
- NAID
  130007411561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06908
[Journal Article] Biochemical and Morphological Characterization of a Neurodevelopmental Disorder-Related Mono-ADP-Ribosylhydrolase, MACRO Domain Containing 2.2018
- Author(s)
  Ito H, Morishita R, Mizuno M, Kawamura N, Tabata H, Nagata KI.
- Journal Title
  
  Dev Neurosci.
  
  Volume: 40 Pages: 278-287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07989
[Journal Article] Expression analyses of Phactr1 (phosphatase and actin regulator 1) during mouse brain development.2018
- Author(s)
  Ito H, Mizuno M, Noguchi K, Morishita R, Iwamoto I, Hara A, Nagata KI.
- Journal Title
  
  Neurosci Res.
  
  Volume: 128 Pages: 50-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07989
[Journal Article] Role of a circadian-relevant gene NR1D1 in brain development: possible involvement in the pathophysiology of autism spectrum disorders.2017
- Author(s)
  Goto M, Mizuno M, Matsumoto A, Yang Z, Jimbo EF, Tabata H, Yamagata T, Nagata KI.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Pages: 43945-43945
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07989
[Journal Article] Expression analyses of Dusp22 (Dual-specificity phosphatase 22) in mouse tissues.2017
- Author(s)
  Hamada N, Mizuno M, Tomita H, Iwamoto I, Hara A, Nagata KI.
- Journal Title
  
  Med Mol Morphol.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07989
[Journal Article] Role of an adaptor protein Lin-7B in brain development: possible involvement in autism spectrum disorders.2015
- Author(s)
  Mizuno M, Matsumoto A, Hamada N, Ito H, Miyauchi A, Jimbo EF, Momoi MY, Tabata H, Yamagata T, Nagata K.
- Journal Title
  
  J Neurochem
  
  Volume: 132 Issue: 1 Pages: 61-69
- DOI
  10.1111/jnc.12943
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590124, KAKENHI-PROJECT-24500386, KAKENHI-PUBLICLY-25123727, KAKENHI-PROJECT-25430046, KAKENHI-PROJECT-26893252, KAKENHI-PUBLICLY-25122722, KAKENHI-PROJECT-24590314, KAKENHI-PROJECT-24390271
[Journal Article] Pathological Implications of Oxidative Stress in Patients and Animal Models with Schizophrenia: The Role of Epidermal Growth Factor Receptor Signaling.2015
- Author(s)
  Nagano T, Mizuno M, Morita K, Nawa H.
- Journal Title
  
  Curr Top Behav Neurosci.
  
  Volume: なし Pages: 1-18
- Data Source
  KAKENHI-PROJECT-15K07989
[Journal Article] LIN7A Depletion Disrupts Cerebral Cortex Development, Contributing to Intellectual Disability in 12q21-Deletion Syndrome.2014
- Author(s)
  Matsumoto A, Mizuno M, Hamada N, Nozaki Y, Jimbo EF, Momoi MY, Nagata K, Yamagata T.
- Journal Title
  
  PLoS One
  
  Volume: 9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590314
[Journal Article] ErbB Inhibitors Ameliorate Behavioral Impairments of An Animal Model for Schizophrenia; Implication of Their Dopamine-Modulatory Actions.2013
- Author(s)
  Mizuno M, Sotoyama H, Namba H, Shibuya M, Eda T, Wang R, Okubo T, Nagata K,Iwakura Y, Nawa H.
- Journal Title
  
  Transl Psychiatry
  
  Volume: 3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590314
[Journal Article] Nawa H Pallidal Hyperdopaminergic Innervation Underlying D2 Receptor-Dependent Behavioral Deficits in the Schizophrenia Animal Model Established by EGF2011
- Author(s)
  Sotoyama H, Zheng Y, Iwakura Y, Mizuno M, Aizawa M, Shcherbakova K, Wang R, Namba H
- Journal Title
  
  PLoS One
  
  Volume: 6 Pages: 25831-25831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790245
[Journal Article] Activation of mammalian target of rapamycin signaling in spatial learning2010
- Author(s)
  Qi S, Mizuno M, Yonezawa K, Nawa H, Takei N
- Journal Title
  
  Neurosci Res
  
  Volume: 68 Pages: 88-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790245
[Journal Article] The anthraquinone derivative emodin attenuates methamphetamine-induced hyperlocomotion and startle response in rats2010
- Author(s)
  Mizuno M, Kawamura H, Ishizuka Y, Sotoyama H, Nawa H
- Journal Title
  
  Pharmacol Biochem Behav
  
  Volume: 97 Pages: 392-398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790245
[Journal Article] Antipsychotic potentical of quinazoline ErbB1 inhibitors in a schizophrenia model established with neonatal hippocampal lesioning2010
- Author(s)
  Mizuno M, Shibuya M, Zheng Y, Sotoyama H, Eda Y, Iwakura Y, Kato T, Takasu K, Nawa H
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 114 Pages: 320-331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790245
[Journal Article] The anthraquinone derivative Emodin ameliorates neurobehavioral deficits of a rodent model for schizophrenia2008
- Author(s)
  Mizuno M, Kawamura H, Takei N, Nawa H
- Journal Title
  
  J Neural Transm 115
  
  Pages: 521-530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790203
[Journal Article] Common behavioral influences of the ErbB1 ligands transforming growth factor alpha and epiregulin administered to mouse neonates2008
- Author(s)
  Tsuda N, Mizuno M, Yamanaka T, Komurasaki T, Yoshimoto M, Nawa H
- Journal Title
  
  Brain Dev 30
  
  Pages: 533-543
- NAID
  10025577732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790203
[Journal Article] Conditioned place preference and locomotor sensitization after repeated administration of cocaine or methamphetamine in rats treated with epidermal growth factor during the neonatal period.2004
- Author(s)
  Mizuno M, 他3名
- Journal Title
  
  Ann N Y Acad Sci. 1025
  
  Pages: 612-618
- Data Source
  KAKENHI-PROJECT-13GS0014
[Presentation] Antipsychotic potential of thalidomide in immune/inflammatory model for schizophreni2013
- Author(s)
  Makoto Mizuno, Hiroyuki Nawa, Ko-ichi Nagata
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego Convention Center, San Diego, USA
- Data Source
  KAKENHI-PROJECT-24590314
[Presentation] Antipsychotic potential of antioxidative agents in immune /inflammatory model for schizophrenia2012
- Author(s)
  水野誠
- Organizer
  ２０１２年北米神経科学会
- Place of Presentation
  アメリカ合衆国（ニューオリンズ市）
- Data Source
  KAKENHI-PROJECT-24590314
[Presentation] Antipsychotic potential of thalidomide and lenalidomide in immune/inflammatory models for schizophrenia2011
- Author(s)
  水野誠、鄭英君、那波宏之
- Organizer
  Advancing Drug Discovery for Schizophrenia
- Place of Presentation
  アメリカ合衆国・ニューヨーク
- Year and Date
  2011-03-09
- Data Source
  KAKENHI-PROJECT-22790245
[Presentation] Antipsychotic potential of thalidomide and lenalidomide in immune/inflammatory models for schizophrenia2011
- Author(s)
  水野誠
- Organizer
  Advancing Drug Discovery for Schizophrenia
- Place of Presentation
  ニューヨーク、アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-22790245
[Presentation] Effects of antioxidative agents on behavioral impairments in schizophrenia models2010
- Author(s)
  水野誠、森田影介、那波宏之
- Organizer
  第40回北米神経科学会
- Place of Presentation
  サンディエゴ、アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-22790245
[Presentation] Function of EGF receptor signaling in the neonatal hippocampal lesion model of schizophrenia2009
- Author(s)
  水野誠
- Organizer
  第52回本神経化学会大会
- Place of Presentation
  群馬県
- Data Source
  KAKENHI-PROJECT-20790203
[Presentation] Function of EGF receptor signaling in the neonatal hippocampal lesion model of schizophrenia2009
- Author(s)
  水野誠
- Organizer
  第39回北米神経科学会
- Place of Presentation
  シカゴ、アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-20790203
[Presentation] Effects of tyrosine kinase inhibitors on behavioral experiments in the neonatal hippocampal lesion model of schizophrenia2008
- Author(s)
  水野誠、鄭英君、外山英和、那波宏之
- Organizer
  第38回北米神経科学会
- Place of Presentation
  ワシントンDC、アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-20790203
[Presentation] Effects of emodin for behavioral impairment in models of schizophrenia2008
- Author(s)
  水野誠
- Organizer
  ニューロサイエンス2008
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-20790203
[Presentation] Antipsychotic effects of ErbB1 tyrosine kinase inhibitors on behavioral deficits in the neonatal hippocampal lesion model of schizophrenia2008
- Author(s)
  水野誠、鄭英君、川村宏樹、那波宏之
- Organizer
  第51回日本神経化学会大会
- Place of Presentation
  富山県
- Data Source
  KAKENHI-PROJECT-20790203
[Presentation] Antipsychotic potential of antioxidative agents in models for schizophrenia
- Author(s)
  Makoto Mizuno, Ko-ichi Nagata
- Organizer
  FENS
- Place of Presentation
  Milan, Italy
- Year and Date
  2014-07-05 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-24590314

1. 那波宏之 (50183083)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 武井延之 (70221372)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 高橋誠 (40323985)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 豊岡和彦 (90345504)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 柿田明美 (80281012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 難波寿明 (90332650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 高橋均 (90206839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 村竹辰之 (60311669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 伊東秀記

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIZUNO Makoto 水野 誠

水野 誠 ミズノ マコト

Research Projects

Research Products

Co-Researchers

脳内炎症による行動異常に対する大脳皮質神経細胞移動の関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of cognitive behavioral disorders induced by neurotrophic factor in developmental dopaminergic neuronPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of prostaglandins in cognitive function induced by brain inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Antipsychotic potential of antioxidative agents in animal model for schizophreniaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of dopaminergic neuron development by trophic factor and neurofunction disorderPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

局所的mRNA翻訳マシナリーの活性化と脳高次機能

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

精神疾患の遺伝子発現データベースの構築と分子病態解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

プロスタグランジンの認知・記憶に対する影響とその生理メカニズムPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

精神疾患の遺伝子発現データベースの構築と分子病態解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳内サイトカインによる中枢神経機能の制御メカニズム:分子から精神活動へ

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] Rho family GTPases, Rac and Cdc42 control the localization of neonatal dentate granule cells during brain development.2018

Author(s)

Journal Title

Data Source

[Journal Article] Biochemical and Morphological Characterization of a Guanine Nucleotide Exchange Factor ARHGEF9 in Mouse Tissues.2018

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Biochemical and Morphological Characterization of a Neurodevelopmental Disorder-Related Mono-ADP-Ribosylhydrolase, MACRO Domain Containing 2.2018

Author(s)

Journal Title

Data Source

[Journal Article] Expression analyses of Phactr1 (phosphatase and actin regulator 1) during mouse brain development.2018

Author(s)

Journal Title

MIZUNO Makoto 水野誠

水野誠ミズノマコト