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MIZUNO Makoto  水野 誠

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… Alternative Names

水野 誠  ミズノ マコト

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Researcher Number 20345515
External Links
Affiliation (based on the past Project Information) *help 2012 – 2018: 愛知県心身障害者コロニー発達障害研究所, 神経制御学部, 主任研究員
2011: 新潟大学, 脳研究所, 特任准教授
2008 – 2010: Niigata University, 超域研究機構, 准教授
2006: 新潟大学, 脳研究所, 助教授
2005: 新潟大学, 超域研究機構, 助教授
2002 – 2004: 新潟大学, 脳研究所, 助手
Review Section/Research Field
Principal Investigator
General pharmacology / Basic Section 48030:Pharmacology-related / Pharmacology in pharmacy / Pathological medical chemistry
Except Principal Investigator
Biological Sciences
Keywords
Principal Investigator
発達障害 / ドパミン / 認知 / 栄養因子 / 大脳皮質 / 炎症 / 社会性行動 / 行動解析 / 脳内炎症 / 活性酵素 … More / 統合失調症 / 活性酸素 / 情動 / 脳内注入 / 行動学 / シクロオキシゲナーゼ / 驚愕反応 / 認知機能 / プロスタグランジン … More
Except Principal Investigator
分子診断 / DNAチップ / 精神疾患 / eEF2キナーゼ / eEF2 / 翻訳伸展 / ニューロン / p70S6K / 4EBP / BDNF / 局所的蛋白合成 / 海馬 / 空間学習 / 翻訳調節 / mTOR / 遺伝子プロファイル / マイクロアレイ / 遺伝子発現 / 単核球 / 総合失調症 / モデル動物 / 神経発達 / 脳栄養因子 / ストレス / 認知行動 / 上皮成長因子 / 統合失調症 / 栄養因子 / 脳発達 / ドパミン / サイトカイン Less
  • Research Projects

    (10 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (9 People)
  •  脳内炎症による行動異常に対する大脳皮質神経細胞移動の関与Principal Investigator

    • Principal Investigator
      水野 誠
    • Project Period (FY)
      2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Institute for Developmental Research, Aichi Human Service Center
  •  Analysis of cognitive behavioral disorders induced by neurotrophic factor in developmental dopaminergic neuronPrincipal Investigator

    • Principal Investigator
      MIZUNO MAKOTO
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pharmacology in pharmacy
    • Research Institution
      Institute for Developmental Research, Aichi Human Service Center
  •  Involvement of prostaglandins in cognitive function induced by brain inflammationPrincipal Investigator

    • Principal Investigator
      MAKOTO MIZUNO
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Institute for Developmental Research, Aichi Human Service Center
  •  Antipsychotic potential of antioxidative agents in animal model for schizophreniaPrincipal Investigator

    • Principal Investigator
      MIZUNO Makoto
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      Niigata University
  •  Regulation of dopaminergic neuron development by trophic factor and neurofunction disorderPrincipal Investigator

    • Principal Investigator
      MIZUNO Makoto
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      Niigata University
  •  局所的mRNA翻訳マシナリーの活性化と脳高次機能

    • Principal Investigator
      武井 延之
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Niigata University
  •  精神疾患の遺伝子発現データベースの構築と分子病態解析

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Niigata University
  •  プロスタグランジンの認知・記憶に対する影響とその生理メカニズムPrincipal Investigator

    • Principal Investigator
      水野 誠
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Niigata University
  •  精神疾患の遺伝子発現データベースの構築と分子病態解析

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Niigata University
  •  脳内サイトカインによる中枢神経機能の制御メカニズム:分子から精神活動へ

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Niigata University

All 2018 2017 2015 2014 2013 2012 2011 2010 2009 2008 2004 Other

All Journal Article Presentation

  • [Journal Article] Rho family GTPases, Rac and Cdc42 control the localization of neonatal dentate granule cells during brain development.2018

    • Author(s)
      Ito H, Morishita R, Mizuno M, Tabata H, Nagata KI.
    • Journal Title

      Hippocampus.

      Volume: Nov Pages: 2-2

    • Data Source
      KAKENHI-PROJECT-15K07989
  • [Journal Article] Biochemical and Morphological Characterization of a Guanine Nucleotide Exchange Factor ARHGEF9 in Mouse Tissues.2018

    • Author(s)
      Ibaraki K, Mizuno M, Aoki H, Niwa A, Iwamoto I, Hara A, Tabata H, Ito H, Nagata KI.
    • Journal Title

      Acta Histochem Cytochem

      Volume: 51 Pages: 119-128

    • NAID

      130007411561

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06908
  • [Journal Article] Biochemical and Morphological Characterization of a Neurodevelopmental Disorder-Related Mono-ADP-Ribosylhydrolase, MACRO Domain Containing 2.2018

    • Author(s)
      Ito H, Morishita R, Mizuno M, Kawamura N, Tabata H, Nagata KI.
    • Journal Title

      Dev Neurosci.

      Volume: 40 Pages: 278-287

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07989
  • [Journal Article] Expression analyses of Phactr1 (phosphatase and actin regulator 1) during mouse brain development.2018

    • Author(s)
      Ito H, Mizuno M, Noguchi K, Morishita R, Iwamoto I, Hara A, Nagata KI.
    • Journal Title

      Neurosci Res.

      Volume: 128 Pages: 50-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07989
  • [Journal Article] Role of a circadian-relevant gene NR1D1 in brain development: possible involvement in the pathophysiology of autism spectrum disorders.2017

    • Author(s)
      Goto M, Mizuno M, Matsumoto A, Yang Z, Jimbo EF, Tabata H, Yamagata T, Nagata KI.
    • Journal Title

      Sci Rep.

      Volume: 7 Pages: 43945-43945

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07989
  • [Journal Article] Expression analyses of Dusp22 (Dual-specificity phosphatase 22) in mouse tissues.2017

    • Author(s)
      Hamada N, Mizuno M, Tomita H, Iwamoto I, Hara A, Nagata KI.
    • Journal Title

      Med Mol Morphol.

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07989
  • [Journal Article] Role of an adaptor protein Lin-7B in brain development: possible involvement in autism spectrum disorders.2015

    • Author(s)
      Mizuno M, Matsumoto A, Hamada N, Ito H, Miyauchi A, Jimbo EF, Momoi MY, Tabata H, Yamagata T, Nagata K.
    • Journal Title

      J Neurochem

      Volume: 132 Issue: 1 Pages: 61-69

    • DOI

      10.1111/jnc.12943

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23590124, KAKENHI-PROJECT-24500386, KAKENHI-PUBLICLY-25123727, KAKENHI-PROJECT-25430046, KAKENHI-PROJECT-26893252, KAKENHI-PUBLICLY-25122722, KAKENHI-PROJECT-24590314, KAKENHI-PROJECT-24390271
  • [Journal Article] Pathological Implications of Oxidative Stress in Patients and Animal Models with Schizophrenia: The Role of Epidermal Growth Factor Receptor Signaling.2015

    • Author(s)
      Nagano T, Mizuno M, Morita K, Nawa H.
    • Journal Title

      Curr Top Behav Neurosci.

      Volume: なし Pages: 1-18

    • Data Source
      KAKENHI-PROJECT-15K07989
  • [Journal Article] LIN7A Depletion Disrupts Cerebral Cortex Development, Contributing to Intellectual Disability in 12q21-Deletion Syndrome.2014

    • Author(s)
      Matsumoto A, Mizuno M, Hamada N, Nozaki Y, Jimbo EF, Momoi MY, Nagata K, Yamagata T.
    • Journal Title

      PLoS One

      Volume: 9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590314
  • [Journal Article] ErbB Inhibitors Ameliorate Behavioral Impairments of An Animal Model for Schizophrenia; Implication of Their Dopamine-Modulatory Actions.2013

    • Author(s)
      Mizuno M, Sotoyama H, Namba H, Shibuya M, Eda T, Wang R, Okubo T, Nagata K,Iwakura Y, Nawa H.
    • Journal Title

      Transl Psychiatry

      Volume: 3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590314
  • [Journal Article] Nawa H Pallidal Hyperdopaminergic Innervation Underlying D2 Receptor-Dependent Behavioral Deficits in the Schizophrenia Animal Model Established by EGF2011

    • Author(s)
      Sotoyama H, Zheng Y, Iwakura Y, Mizuno M, Aizawa M, Shcherbakova K, Wang R, Namba H
    • Journal Title

      PLoS One

      Volume: 6 Pages: 25831-25831

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790245
  • [Journal Article] Activation of mammalian target of rapamycin signaling in spatial learning2010

    • Author(s)
      Qi S, Mizuno M, Yonezawa K, Nawa H, Takei N
    • Journal Title

      Neurosci Res

      Volume: 68 Pages: 88-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790245
  • [Journal Article] The anthraquinone derivative emodin attenuates methamphetamine-induced hyperlocomotion and startle response in rats2010

    • Author(s)
      Mizuno M, Kawamura H, Ishizuka Y, Sotoyama H, Nawa H
    • Journal Title

      Pharmacol Biochem Behav

      Volume: 97 Pages: 392-398

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790245
  • [Journal Article] Antipsychotic potentical of quinazoline ErbB1 inhibitors in a schizophrenia model established with neonatal hippocampal lesioning2010

    • Author(s)
      Mizuno M, Shibuya M, Zheng Y, Sotoyama H, Eda Y, Iwakura Y, Kato T, Takasu K, Nawa H
    • Journal Title

      J Pharmacol Sci

      Volume: 114 Pages: 320-331

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790245
  • [Journal Article] The anthraquinone derivative Emodin ameliorates neurobehavioral deficits of a rodent model for schizophrenia2008

    • Author(s)
      Mizuno M, Kawamura H, Takei N, Nawa H
    • Journal Title

      J Neural Transm 115

      Pages: 521-530

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790203
  • [Journal Article] Common behavioral influences of the ErbB1 ligands transforming growth factor alpha and epiregulin administered to mouse neonates2008

    • Author(s)
      Tsuda N, Mizuno M, Yamanaka T, Komurasaki T, Yoshimoto M, Nawa H
    • Journal Title

      Brain Dev 30

      Pages: 533-543

    • NAID

      10025577732

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790203
  • [Journal Article] Conditioned place preference and locomotor sensitization after repeated administration of cocaine or methamphetamine in rats treated with epidermal growth factor during the neonatal period.2004

    • Author(s)
      Mizuno M, 他3名
    • Journal Title

      Ann N Y Acad Sci. 1025

      Pages: 612-618

    • Data Source
      KAKENHI-PROJECT-13GS0014
  • [Presentation] Antipsychotic potential of thalidomide in immune/inflammatory model for schizophreni2013

    • Author(s)
      Makoto Mizuno, Hiroyuki Nawa, Ko-ichi Nagata
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego Convention Center, San Diego, USA
    • Data Source
      KAKENHI-PROJECT-24590314
  • [Presentation] Antipsychotic potential of antioxidative agents in immune /inflammatory model for schizophrenia2012

    • Author(s)
      水野誠
    • Organizer
      2012年北米神経科学会
    • Place of Presentation
      アメリカ合衆国(ニューオリンズ市)
    • Data Source
      KAKENHI-PROJECT-24590314
  • [Presentation] Antipsychotic potential of thalidomide and lenalidomide in immune/inflammatory models for schizophrenia2011

    • Author(s)
      水野誠、鄭英君、那波宏之
    • Organizer
      Advancing Drug Discovery for Schizophrenia
    • Place of Presentation
      アメリカ合衆国・ニューヨーク
    • Year and Date
      2011-03-09
    • Data Source
      KAKENHI-PROJECT-22790245
  • [Presentation] Antipsychotic potential of thalidomide and lenalidomide in immune/inflammatory models for schizophrenia2011

    • Author(s)
      水野誠
    • Organizer
      Advancing Drug Discovery for Schizophrenia
    • Place of Presentation
      ニューヨーク、アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-22790245
  • [Presentation] Effects of antioxidative agents on behavioral impairments in schizophrenia models2010

    • Author(s)
      水野誠、森田影介、那波宏之
    • Organizer
      第40回北米神経科学会
    • Place of Presentation
      サンディエゴ、アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-22790245
  • [Presentation] Function of EGF receptor signaling in the neonatal hippocampal lesion model of schizophrenia2009

    • Author(s)
      水野誠
    • Organizer
      第52回本神経化学会大会
    • Place of Presentation
      群馬県
    • Data Source
      KAKENHI-PROJECT-20790203
  • [Presentation] Function of EGF receptor signaling in the neonatal hippocampal lesion model of schizophrenia2009

    • Author(s)
      水野誠
    • Organizer
      第39回北米神経科学会
    • Place of Presentation
      シカゴ、アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-20790203
  • [Presentation] Effects of tyrosine kinase inhibitors on behavioral experiments in the neonatal hippocampal lesion model of schizophrenia2008

    • Author(s)
      水野誠、鄭英君、外山英和、那波宏之
    • Organizer
      第38回北米神経科学会
    • Place of Presentation
      ワシントンDC、アメリカ合衆国
    • Data Source
      KAKENHI-PROJECT-20790203
  • [Presentation] Effects of emodin for behavioral impairment in models of schizophrenia2008

    • Author(s)
      水野誠
    • Organizer
      ニューロサイエンス2008
    • Place of Presentation
      ワシントンDC
    • Year and Date
      2008-11-19
    • Data Source
      KAKENHI-PROJECT-20790203
  • [Presentation] Antipsychotic effects of ErbB1 tyrosine kinase inhibitors on behavioral deficits in the neonatal hippocampal lesion model of schizophrenia2008

    • Author(s)
      水野誠、鄭英君、川村宏樹、那波宏之
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      富山県
    • Data Source
      KAKENHI-PROJECT-20790203
  • [Presentation] Antipsychotic potential of antioxidative agents in models for schizophrenia

    • Author(s)
      Makoto Mizuno, Ko-ichi Nagata
    • Organizer
      FENS
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2014-07-05 – 2014-07-09
    • Data Source
      KAKENHI-PROJECT-24590314
  • 1.  那波 宏之 (50183083)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  武井 延之 (70221372)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  高橋 誠 (40323985)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  豊岡 和彦 (90345504)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  柿田 明美 (80281012)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  難波 寿明 (90332650)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  高橋 均 (90206839)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  村竹 辰之 (60311669)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  伊東 秀記
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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