SUZUKI Yuko 鈴木優子

Researcher Number	20345812
Other IDs
External Links
Affiliation (Current)	2025: 浜松医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2025: 浜松医科大学, 医学部, 教授 2011 – 2020: 浜松医科大学, 医学部, 准教授 2007 – 2010: Hamamatsu University School of Medicine, 医学部, Assistant Professor 2006: 浜松医科大学, 医学部, 助手 2002: Hamamatsu Univ. Sch. Of Med. Dept. of Physiology Assistant, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Circulatory organs internal medicine / Basic Section 52010:General internal medicine-related / Cardiovascular medicine Except Principal Investigator General physiology / Basic Section 59040:Nutrition science and health science-related / Basic Section 54010:Hematology and medical oncology-related / Basic Section 55060:Emergency medicine-related / Basic Section 56070:Plastic and reconstructive surgery-related / Basic Section 53030:Respiratory medicine-related … More / Cardiovascular surgery / Metabolomics / General physiology / Hematology Less
Keywords	Principal Investigator 可視化解析 / 血管内皮細胞 / 線溶活性 / トロンビン活性 / トロンボモジュリン / 蛍光顕微鏡 / リアルタイムイメージング解析 / 組織型プラスミノゲンアクチベータ / 組織型プラスミノゲンアクチベーター / 線溶抑制機能不全 … More / 止血血栓 / 血栓止血 / 抗凝固薬 / 向凝固薬 / トロンビン / トロンビン活性化線溶阻害因子 / 線溶抑制系 / 抗血栓療法 / 疑似血管モデル / 時空間的制御機構 / 血栓形成溶解 / 線溶 / 直接経口抗凝固薬 / プラスミノゲン集積 / 活性化血小板 / 線溶反応 / トロンビン活性化線溶抑制因子 / トロンビン生成 / 血栓形成 / 血小板 / 線維素溶解（線溶） / 糖鎖 / 定量解析 / 流れずり応力 / tenecteplase / 内皮バリア機能 / プラスミノゲンアクチベータインヒビター１ / 組織プラスミノゲンアクチベータ / 血管トーヌス / プラスミノーゲンアクチベーターインヒビター1 / 反射蛍光顕微鏡 / 組織プラスミノーゲンアクチベーター / プラスミノゲンアクチベーターインヒビター1 / 全反射蛍光顕微鏡 / 開口放出 … More Except Principal Investigator PAI-1 / 血管内皮細胞 / 血小板 / 線溶 / 血管新生 / 内皮細胞 / iPS細胞 / 凝固 / 非侵襲生体光イメージング技術 / 生体代謝活動計測 / 非線形光学顕微鏡 / 血管生理学 / イメージング / 血栓溶解 / トロンボモジュリン / TAFI / ADAMTS13 / GFP / PAI-2 / 脂肪細胞 / 細胞接着 / endothelial cells / iPS cells / 血液凝固 / 線維素溶解(線溶） / 線溶検査法 / 外傷 / 線溶測定法 / 頭部外傷 / antiplasmin / 線溶抵抗性 / α2-Antiplasmin / 線維素溶解現象 / オルガノイドモデル / 創傷治癒 / 線維素溶解反応 / 血栓形成能可視化 / 血管閉塞 / 分子標的薬 / 慢性骨髄性白血病 / 動脈硬化 / 慢性閉塞性肺疾患（COPD） / ヘモダイナミクス / 線維素溶解 / 遺伝子編集 / 凝固線溶系 / 疾患特異的iPS細胞 / 細胞動態機能 / 線溶反応 / 大血管外科学 / 心臓血管外科学 / 生体イメージング / モデル動物 / 大動脈瘤 / 腹部大動脈瘤 / 血管愛内皮細胞 / 血管内皮 / プラスミノゲンアクチベータ / トロンビン活性化線溶阻害因子 / プラスミノゲン / 細胞内代謝 / 細胞分化 / adipocytes / vascular endothelinl cell / platelet / Thrombotic Thrombocytopenic Purpura / vo Willebrand Factor / intra vital confocal microscopy / thrombus formation / von Willebrand因子 / 血栓性血小板減少性紫斑病 / von Willebrand 因子 / 生体内顕微鏡 / 血栓形成 / urokinase / urokinase receptor / cell migration / cell adhesion / ウロキナーゼ / ウロキナーゼ受容体 / 細胞移動 / 血球細胞 / 発生・分化 / 凝固・線溶 / angiogenesis / 血栓 / carboxylpeptidase / plasminogen / 血液レオロジー Less

生体血管ライブイメージングにより解明する血栓形成溶解機構Principal Investigator
- Principal Investigator
  
  鈴木優子
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Hamamatsu University School of Medicine
血流分配を担う血管制御因子の非侵襲生体機能計測
- Principal Investigator
  
  本藏直樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Hamamatsu University School of Medicine
Novel therapeutic strategies for COPD targeting the fibrinolysis inhibitor PAI-1
- Principal Investigator
  
  安井秀樹
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Hamamatsu University School of Medicine
Development of prevention method for tyrosine kinase inhibitor for chronic myeloid leukemia-induced vascular occlusion based on visualization of thrombogenicity
- Principal Investigator
  
  小野孝明
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Hamamatsu University School of Medicine
The role of fibrinolytic function in the angiogenic microenvironment of wound healing using vascularized organoids
- Principal Investigator
  
  佐野秀人
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tokai University
Real-time imaging analysis of hemostatic thrombus stabilization and its failurePrincipal Investigator
- Principal Investigator
  
  鈴木優子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Hamamatsu University School of Medicine
Elucidation of pathophysiology of uncontrolled bleeding due to disruption of spatiotemporal regulation of fibrinolysis by imaging analysis and newly established laboratory test.
- Principal Investigator
  
  浦野哲盟
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Hamamatsu University School of Medicine
Intravital Imaging for Nutrient Regulation in Vascular Endothelial Cells Interconnected with Local Cells Metabolism
- Principal Investigator
  
  Honkura Naoki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Hamamatsu University School of Medicine
Analysis of coagulation and fibrinolytic functions and vascular endothelium-platelet interaction using disease-specific iPS cells
- Principal Investigator
  
  SANO Hideto
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Hamamatsu University School of Medicine
Understanding in spatio-temporal regulation mechanism of thrombus formation and dissolution for realization of appropriate antithrombotic therapyPrincipal Investigator
- Principal Investigator
  
  Suzuki Yuko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Hamamatsu University School of Medicine
Vasa Vasorum in Abdominal Aortic Aneurysm
- Principal Investigator
  
  TANAKA Hiroki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Hamamatsu University School of Medicine
Various reguratory mechanisms of activated-platelet' memberane-based activation of fibrinolysis.
- Principal Investigator
  
  Urano Tetsumei
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Hamamatsu University School of Medicine
The intrinsic roles of human PAI-1 in adipocyte differentiation and function with using patient-derived iPS cells.
- Principal Investigator
  
  Sano Hideto
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Hamamatsu University School of Medicine
Elucidation of intrinsic fibrinolytic activities potentiated vascular endothelial cells and its possibility in prophylaxis of thrombotic diseasePrincipal Investigator
- Principal Investigator
  
  Suzuki Yuko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Hamamatsu University School of Medicine
Role of phosphatidylserine on activated platelets on tissue factor initiated blood coagulation
- Principal Investigator
  
  URANO TETSUMEI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Hamamatsu University School of Medicine
Generation of iPS cells from PAI-1 deficient patient and differentiation into mature cells
- Principal Investigator
  
  SANO Hideto
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Hamamatsu University School of Medicine
Imaging analysis of the role of newly proposed cell surface-associated fibrinolysis mechanism in the regulation of endothelial barrier function.Principal Investigator
- Principal Investigator
  
  SUZUKI Yuko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Hamamatsu University School of Medicine
Imaging analysis of phosphatidylserine-evoked initiation of coagulation cascade on activated platelets surface.
- Principal Investigator
  
  URANO Tetsumei
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Hamamatsu University School of Medicine
Unique secretory dynamics of tissue plasminogen activator and vascular functionPrincipal Investigator
- Principal Investigator
  
  SUZUKI Yuko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Hamamatsu University School of Medicine
Real time imaging analysis of platelets aggregation and thrombus formation under shear stress
- Principal Investigator
  
  URANO Tetsumei
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Hamamatsu University School of Medicine
Real time imaging analysis of molecular interactions of factors involved in fibrinolysis on cell surface to modify cell migration
- Principal Investigator
  
  URANO Tetsumei
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Hamamatsu University School of Medicine

[Book] 新・血栓止血血管学「抗凝固と線溶」2015
- Author(s)
  鈴木優子、他　多数
- Total Pages
  133
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-25461123
[Book] 血栓止血ハンドブック2015
- Author(s)
  鈴木重統、松野一彦、後藤信哉
- Total Pages
  422
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-25461123
[Book] 日本血栓止血学会用語集web版2015
- Author(s)
  鈴木優子、他　多数
- Publisher
  日本血栓止血学会
- Data Source
  KAKENHI-PROJECT-25461123
[Book] 止血・血栓ハンドブック2014
- Author(s)
  浦野哲盟、鈴木優子
- Total Pages
  422
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-24590273
[Book] Annual Review血液20122012
- Author(s)
  鈴木優子
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22590826
[Book] Annual Review 血液2012
- Author(s)
  鈴木優子 (分担執筆)
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22590826
[Journal Article] Evaluation of thrombomodulin/TAFI function in plasma using tPA-induced plasma clot lysis time.2024
- Author(s)
  Tetsumei Urano , Yoshie Sano , Yuji Suzuki , Masahiko Okada , Hideto Sano , Naoki Honkura , Nanami Morooka , Matsuyuki Doi , Yuko Suzuki
- Journal Title
  
  Research and Practice in Thrombosis and Haemostasis (RPTH)
  
  Volume: in press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24431
[Journal Article] Evaluation of fibrinolysis by real time-imaging analysis2023
- Author(s)
  SUZUKI Yuko、URANO Tetsumei
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis
  
  Volume: 34 Issue: 3 Pages: 338-344
- DOI
  10.2491/jjsth.34.338
- ISSN
  0915-7441, 1880-8808
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-22K08153, KAKENHI-PROJECT-23K24431
[Journal Article] Visualization of Domain- and Concentration-Dependent Impact of Thrombomodulin on Differential Regulation of Coagulation and Fibrinolysis2023
- Author(s)
  Mochizuki Liina、Sano Hideto、Honkura Naoki、Masumoto Kazuma、Urano Tetsumei、Suzuki Yuko
- Journal Title
  
  Thrombosis and Haemostasis
  
  Volume: 123 Issue: 01 Pages: 016-026
- DOI
  10.1055/s-0042-1757407
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08153, KAKENHI-PROJECT-20K08710, KAKENHI-PROJECT-23K24431
[Journal Article] Measurement of total PAI-1 and interpretation of results—especially for low PAI-1 values2023
- Author(s)
  IWAKI Takayuki、UMEMURA Kazuo、SUZUKI Yuko、URANO Tetsumei
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis
  
  Volume: 34 Issue: 3 Pages: 304-309
- DOI
  10.2491/jjsth.34.304
- ISSN
  0915-7441, 1880-8808
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-22K08153, KAKENHI-PROJECT-23K24431
[Journal Article] Global fibrinolytic assay (clot lysis assay)2023
- Author(s)
  URANO Tetsumei、SUZUKI Yuko、IWAKI Takayuki
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis
  
  Volume: 34 Issue: 3 Pages: 292-298
- DOI
  10.2491/jjsth.34.292
- ISSN
  0915-7441, 1880-8808
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-22K08153, KAKENHI-PROJECT-23K24431
[Journal Article] What we want to know from the laboratory tests on fibrinolysis2023
- Author(s)
  URANO Tetsumei、SUZUKI Yuko
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis
  
  Volume: 34 Issue: 3 Pages: 286-291
- DOI
  10.2491/jjsth.34.286
- ISSN
  0915-7441, 1880-8808
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-22K08153, KAKENHI-PROJECT-23K24431
[Journal Article] COVID-19 and Thrombosis: Clinical Aspects2022
- Author(s)
  Urano Tetsumei、Yasumoto Atsushi、Yokoyama Kenji、Horiuchi Hisanori、Morishita Eriko、Suzuki Yuko
- Journal Title
  
  Current Drug Targets
  
  Volume: 23 Issue: 17 Pages: 1567-1572
- DOI
  10.2174/1389450123666221005092350
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07391, KAKENHI-PROJECT-22K08153, KAKENHI-PROJECT-23K24431
[Journal Article] Pre-administration of a carboxypeptidase inhibitor enhances tPA-induced thrombolysis in mouse microthrombi: Evidence from intravital imaging analysis2022
- Author(s)
  Mathews Nitty Skariah、Suzuki Yuko、Honkura Naoki、Sano Hideto、Iwashita Toshihide、Urano Tetsumei
- Journal Title
  
  Thrombosis Research
  
  Volume: 210 Pages: 78-86
- DOI
  10.1016/j.thromres.2021.12.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08577, KAKENHI-PROJECT-19K22959, KAKENHI-PROJECT-21H03352, KAKENHI-PROJECT-21K18323, KAKENHI-PROJECT-21K06947, KAKENHI-PROJECT-20K08710
[Journal Article] Demonstration of Three Distinct High-Molecular-Weight Complexes between Plasminogen Activator Inhibitor Type 1 and Tissue-Type Plasminogen Activator2021
- Author(s)
  Ito Tae、Suzuki Yuko、Sano Hideto、Honkura Naoki、Castellino Francis J.、Urano Tetsumei
- Journal Title
  
  Thrombosis and Haemostasis
  
  Volume: 122 Issue: 03 Pages: 336-343
- DOI
  10.1055/a-1508-7919
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08577, KAKENHI-PROJECT-19K22959, KAKENHI-PROJECT-21H03352, KAKENHI-PROJECT-21K18323, KAKENHI-PROJECT-20K08710
[Journal Article] リアルタイムイメージング技術が照らす線溶反応の時空間的制御機構2021
- Author(s)
  鈴木優子
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 32 Pages: 495-503
- NAID
  130008080757
- Data Source
  KAKENHI-PROJECT-19K08577
[Journal Article] Spatiotemporal regulation of thrombus formation and dissolution2020
- Author(s)
  鈴木優子、浦野哲盟
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 61 Issue: 9 Pages: 1349-1357
- DOI
  10.11406/rinketsu.61.1349
- NAID
  130007937061
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-19K08577
[Journal Article] The Role of Animal Models in Elucidating the Etiology and Pathology of Abdominal Aortic Aneurysms: Development of a Novel Rupture Mechanism Model2020
- Author(s)
  Tanaka Hiroki、Zaima Nobuhiro、Kugo Hirona、Yata Tatsuro、Iida Yasunori、Hashimoto Keisuke、Miyamoto Chie、Sasaki Takeshi、Sano Hideto、Suzuki Yuko、Moriyama Tatsuya、Shimizu Hideyuki、Inuzuka Kazunori、Urano Tetsumei、Unno Naoki
- Journal Title
  
  Annals of Vascular Surgery
  
  Volume: 63 Pages: 382-390
- DOI
  10.1016/j.avsg.2019.08.082
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10752, KAKENHI-PROJECT-18K08755, KAKENHI-PROJECT-19K08577, KAKENHI-PROJECT-17H03822, KAKENHI-PROJECT-17K10765, KAKENHI-PROJECT-20K09122
[Journal Article] Activated platelet-based inhibition of fibrinolysis via thrombin-activatable fibrinolysis inhibitor activation system2020
- Author(s)
  Suzuki Yuko、Sano Hideto、Mochizuki Liina、Honkura Naoki、Urano Tetsumei
- Journal Title
  
  Blood Advances
  
  Volume: 4 Issue: 21 Pages: 5501-5511
- DOI
  10.1182/bloodadvances.2020002923
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08577, KAKENHI-PROJECT-20K08710, KAKENHI-PROJECT-19K22959
[Journal Article] Fibrinolysis-resistant carbonylated fibrin detected in thrombi attached to the vascular wall of abdominal aortic aneurysms2020
- Author(s)
  Suzuki Yuko、Tanaka Hiroki、Horinouchi Takahiro、Sano Hideto、Honkura Naoki、Unno Naoki、Miwa Soichi、Urano Tetsumei
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 20728-20728
- DOI
  10.1038/s41598-020-77582-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08577, KAKENHI-PROJECT-20K08710, KAKENHI-PROJECT-19K22959, KAKENHI-PROJECT-18K06697
[Journal Article] Recognition of Plasminogen Activator Inhibitor Type 1 as the Primary Regulator of Fibrinolysis2019
- Author(s)
  Urano T, Suzuki Y, Iwaki T, Sano H, Honkura N, Castellino FJ.
- Journal Title
  
  Curr Drug Targets.
  
  Volume: 20 Issue: 16 Pages: 1695-1701
- DOI
  10.2174/1389450120666190715102510
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10666, KAKENHI-PROJECT-19K08577, KAKENHI-PROJECT-19K22959
[Journal Article] Assessing plasminogen activation potential with global fibrinolytic assays2019
- Author(s)
  Urano Tetsumei、Suzuki Yuko
- Journal Title
  
  Research and Practice in Thrombosis and Haemostasis
  
  Volume: 4 Issue: 1 Pages: 13-15
- DOI
  10.1002/rth2.12293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08577
[Journal Article] G-protein-coupled receptor 40 agonist GW9508 potentiates glucose-stimulated insulin secretion through activation of protein kinase Cα and ε in INS-1 cells2019
- Author(s)
  Hashimoto Takuya、Mogami Hideo、Tsuriya Daisuke、Morita Hiroshi、Sasaki Shigekazu、Kumada Tatsuro、Suzuki Yuko、Urano Tetsumei、Oki Yutaka、Suda Takafumi
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 9 Pages: e0222179-e0222179
- DOI
  10.1371/journal.pone.0222179
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01482, KAKENHI-PROJECT-19K08577
[Journal Article] Hypoperfusion of the aortic wall secondary to degeneration of adventitial vasa vasorum causes abdominal aortic aneurysms2018
- Author(s)
  Tanaka Hiroki、Unno Naoki、Suzuki Yuko、Sano Hideto、Yata Tatsuro、Urano Tetsumei
- Journal Title
  
  Current Drug Targets
  
  Volume: 19 Issue: 11 Pages: 1327-1332
- DOI
  10.2174/1389450119666180122154409
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09411, KAKENHI-PROJECT-17K10751
[Journal Article] Elevated Plasma Levels of LDL Cholesterol Promote Dissecting Thoracic Aortic Aneurysms in Angiotensin II-Induced Mice.2018
- Author(s)
  Tanaka H, Iida Y, Iwaki T, Suzuki Y, Sano H, Miyajima C, Zaima N, Sasaki T, Sumioka A, Hakamata S, Shimizu H, Umemura K, Urano T.
- Journal Title
  
  Ann Vasc Surg.
  
  Volume: 48 Pages: 204-213
- DOI
  10.1016/j.avsg.2017.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10751, KAKENHI-PROJECT-15K09411, KAKENHI-PROJECT-17K10666, KAKENHI-PROJECT-17K10752, KAKENHI-PROJECT-17K10765, KAKENHI-PROJECT-16K08492
[Journal Article] Regulation of Plasminogen Activation on Cell Surfaces and Fibrin.2018
- Author(s)
  Urano T, Castellino FJ, Suzuki Y
- Journal Title
  
  J Thromb Haemost
  
  Volume: 印刷中 Issue: 8 Pages: 1487-1497
- DOI
  10.1111/jth.14157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08492
[Journal Article] Hypoperfusion of the Aortic Wall Secondary to Degeneration of Adventitial Vasa Vasorum Causes Abdominal Aortic Aneurysms.2018
- Author(s)
  Tanaka H, Unno N, Suzuki Y, Sano H, Yata T, Urano T
- Journal Title
  
  Current Drug targets
  
  Volume: 19(11) Pages: 1327-1332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08492
[Journal Article] Mutation in a highly conserved glycine residue in strand 5B of plasminogen activator inhibitor 1 causes polymerization.2017
- Author(s)
  Iwaki T, Nagahashi K, Takano K, Suzuki-Inoue K, Kanayama N, Umemura K, Urano T.
- Journal Title
  
  Thrombosis and Haemostasis
  
  Volume: 117(5) Issue: 05 Pages: 860-869
- DOI
  10.1160/th16-07-0572
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08492, KAKENHI-PROJECT-17K01482, KAKENHI-PROJECT-17K10666
[Journal Article] PC194 Ectopic Expression of Proprotein Convertase Subtilisin Kexin Type 9 by Smooth Muscular Cells Contributes to Aortic Dissection.2017
- Author(s)
  Iida Y, Tanaka H, Urano T, Unno N, Shimizu H.
- Journal Title
  
  J Vasc Surg
  
  Volume: 65(6) Pages: 195-203
- DOI
  10.1016/j.avsg.2017.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08492, KAKENHI-PROJECT-17K10751, KAKENHI-PROJECT-17K10765, KAKENHI-PROJECT-15K09411
[Journal Article] Thrombolytic therapy targeting alpha 2-antiplasmin.2017
- Author(s)
  Urano T, Suzuki Y.
- Journal Title
  
  Circulation
  
  Volume: 135 Issue: 11 Pages: 1021-1023
- DOI
  10.1161/circulationaha.117.026884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08492
[Journal Article] Lysophosphatidylcholine Acyltransferase-3 Expression Is Associated with Atherosclerosis Progression.2017
- Author(s)
  Tanaka H, Zaima N, Sasaki T, Yamamoto N, Inuzuka K, Yata T, Iwaki T, Umemura K, Sano H, Suzuki Y, Urano T, Setou M, Unno N
- Journal Title
  
  J Vasc Res
  
  Volume: 54(4) Issue: 4 Pages: 200-208
- DOI
  10.1159/000473879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08492, KAKENHI-PROJECT-17K10666, KAKENHI-PROJECT-17K10752, KAKENHI-PROJECT-15K09411, KAKENHI-PROJECT-26462104
[Journal Article] Imaging analyses of coagulation-dependent initiation of fibrinolysis on activated platelets and its modification by thrombin-activatable fibrinolysis inhibitor.2017
- Author(s)
  Brzoska T, Suzuki Y, Sano H, Suzuki A, Tanaka H, Urano T
- Journal Title
  
  Thrombosis and Haemostasis
  
  Volume: 7 Issue: 04 Pages: 682-690
- DOI
  10.1160/th16-09-0722
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08492
[Journal Article] Activities of wild-type and variant tissue-type plasminogen activators retained on vascular endothelial cells2016
- Author(s)
  Suzuki Y, Sano H, Tomczyk M, Brzoska T and Urano T
- Journal Title
  
  FEBS Open Bio
  
  Volume: 6 Issue: 5 Pages: 469-476
- DOI
  10.1002/2211-5463.12057
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461123, KAKENHI-PROJECT-15K09411, KAKENHI-PROJECT-16K08492
[Journal Article] Bidirectional functions of thrombin on fibrinolysis: Evidence of thrombin-dependent enhancement of fibrinolysis provided by spontaneous plasma clot lysis.2016
- Author(s)
  Tomczyk M., Suzuki Y., Sano H., Brzoska T., Tanaka H., Urano T.
- Journal Title
  
  Thromb Res.
  
  Volume: 143 Pages: 28-33
- DOI
  10.1016/j.thromres.2016.04.018
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09411, KAKENHI-PROJECT-16K08492
[Journal Article] 線溶系の最新情報と今後の展望2016
- Author(s)
  浦野哲盟、鈴木優子
- Journal Title
  
  臨床血液
  
  Volume: 57 Pages: 333-339
- NAID
  130005145473
- Data Source
  KAKENHI-PROJECT-25461123
[Journal Article] Endogenously Generated Plasmin at the Vascular Wall Injury Site Amplifies Lysine Binding Site-Dependent Plasminogen Accumulation in Microthrombi.2015
- Author(s)
  Brzoska T, Tanaka-Murakami A, Suzuki Y, Sano H, Kanayama N, Urano T.
- Journal Title
  
  PLoSONE
  
  Volume: 10 Issue: 3 Pages: 1371-1371
- DOI
  10.1371/journal.pone.0122196
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590273, KAKENHI-PROJECT-24591420, KAKENHI-PROJECT-25461123, KAKENHI-PROJECT-26860146
[Journal Article] 凝固・線溶系のしくみと血栓形成機序2014
- Author(s)
  浦野哲盟、鈴木優子
- Journal Title
  
  日本臨床
  
  Volume: 72 Pages: 1198-1205
- Data Source
  KAKENHI-PROJECT-24590273
[Journal Article] プラスミノゲンレセプター2014
- Author(s)
  浦野哲盟、鈴木優子
- Journal Title
  
  Annals Review 血液
  
  Volume: 1 Pages: 209-215
- Data Source
  KAKENHI-PROJECT-24590273
[Journal Article] 凝固・線溶系のしくみと血栓形成機序　血栓・塞栓症 ―治療・予防の最新動向―2014
- Author(s)
  浦野哲盟、鈴木優子
- Journal Title
  
  日本臨床
  
  Volume: 72 Pages: 1198-1205
- Data Source
  KAKENHI-PROJECT-25461123
[Journal Article] 凝固線溶系分子による血管内皮細胞機能の維持2014
- Author(s)
  鈴木優子、浦野哲盟
- Journal Title
  
  血液内科
  
  Volume: 69 Pages: 336-342
- Data Source
  KAKENHI-PROJECT-25461123
[Journal Article] 凝固線溶系　プラスミノゲンレセプター2014
- Author(s)
  浦野哲盟、鈴木優子
- Journal Title
  
  Annual Review 血液
  
  Volume: 2014 Pages: 209-215
- Data Source
  KAKENHI-PROJECT-25461123
[Journal Article] 血液凝固における血管内皮細胞と RAS2014
- Author(s)
  鈴木優子、浦野哲盟
- Journal Title
  
  Angiotensin Research
  
  Volume: 11 Pages: 1-6
- Data Source
  KAKENHI-PROJECT-24590273
[Journal Article] 動脈硬化、血栓性疾患発症予防におけるスタチンの特赦な位置付け2013
- Author(s)
  鈴木優子、浦野哲盟
- Journal Title
  
  動脈硬化予防
  
  Volume: 12 Pages: 56-63
- Data Source
  KAKENHI-PROJECT-25461123
[Journal Article] Binding of thrombin-activated platelets to a fibrin scaffold through αIIbβ3evokes phosphatidylserine exposure on their cell surface2013
- Author(s)
  Brzoska T, Suzuki Y, Mogami H, Sano H, Urano T
- Journal Title
  
  PLoS One
  
  Volume: 8(2) Issue: 2 Pages: 55466-55466
- DOI
  10.1371/journal.pone.0055466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590826, KAKENHI-PROJECT-24590273, KAKENHI-PROJECT-24591420, KAKENHI-PROJECT-24604004
[Journal Article] TM5275prolongs secreted tissue plasminogen activator retention and enhancesfibrinolysis on vascular endothelial cells.2013
- Author(s)
  Yasui H, Suzuki Y, Sano H, Suda T, Chida K, Dan T, Miyata T, Urano T
- Journal Title
  
  Thromb Res
  
  Volume: ## Issue: 1 Pages: 100-105
- DOI
  10.1016/j.thromres.2013.04.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590826, KAKENHI-PROJECT-24249033, KAKENHI-PROJECT-24590273, KAKENHI-PROJECT-25461123
[Journal Article] 血液凝固における血管内皮細胞とRASの役割2013
- Author(s)
  鈴木優子、浦野哲盟
- Journal Title
  
  Angiotensin Research
  
  Volume: 11 Pages: 1-6
- Data Source
  KAKENHI-PROJECT-25461123
[Journal Article] 血管内皮の抗血栓作用と線溶関連治療の考え方2013
- Author(s)
  鈴木優子
- Journal Title
  
  Current Therapy
  
  Volume: 31 Pages: 318-323
- Data Source
  KAKENHI-PROJECT-22590826
[Journal Article] 血栓性疾患発症予防におけるスタチンの特殊な位置付け2013
- Author(s)
  鈴木優子、浦野哲盟
- Journal Title
  
  動脈硬化予防
  
  Volume: 12 Pages: 56-63
- Data Source
  KAKENHI-PROJECT-24590273
[Journal Article] 血管内皮の抗血栓作用と線溶関連治療の考え方2013
- Author(s)
  鈴木優子、浦野哲盟
- Journal Title
  
  Current Therapy
  
  Volume: 31 Pages: 318-23
- Data Source
  KAKENHI-PROJECT-22590826
[Journal Article] 血管内皮表面における滞留 tPA惹起線溶活性増幅機構のイメージング解析2012
- Author(s)
  鈴木優子
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 22 Pages: 374-6
- Data Source
  KAKENHI-PROJECT-22590826
[Journal Article] 凝固線溶系：線溶活性低下と血栓症2012
- Author(s)
  鈴木優子、浦野哲盟
- Journal Title
  
  Annual Review 血液
  
  Volume: 2012 Pages: 310-235
- Data Source
  KAKENHI-PROJECT-24590273
[Journal Article] Accelerated fibrinolysis and its propagation on vascular endothelial cells by secreted and retained tPA. J Biomed Biotechnol2012
- Author(s)
  Urano T, Suzuki Y
- Journal Title
  
  J Biomed Biotechnol
  
  Volume: 2012 Pages: 208108-208108
- DOI
  10.1155/2012/208108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590826, KAKENHI-PROJECT-24590273
[Journal Article] 血管内皮細胞上の線溶活性調節機構2012
- Author(s)
  鈴木優子、浦野哲盟
- Journal Title
  
  血液フロンティア
  
  Volume: 21 Pages: 1571-9
- Data Source
  KAKENHI-PROJECT-22590826
[Journal Article] コレステロールと易血栓性2011
- Author(s)
  鈴木優子、浦野哲盟
- Journal Title
  
  循環器内科
  
  Volume: 69 Pages: 170-176
- NAID
  40018756189
- Data Source
  KAKENHI-PROJECT-22590826
[Journal Article] コレステロールと医血栓性2011
- Author(s)
  鈴木優子、浦野哲盟
- Journal Title
  
  循環器内科
  
  Volume: 69 Pages: 170-6
- Data Source
  KAKENHI-PROJECT-22590826
[Journal Article] Parameters related to fibrinolysis and their meanings.2011
- Author(s)
  Urano T, Suzuki Y
- Journal Title
  
  Rinsho Byori.
  
  Volume: 59(7) Pages: 703-8
- NAID
  10029615401
- Data Source
  KAKENHI-PROJECT-22590826
[Journal Article] Novel mechanism of the expression and amplification of cell surface-associated fibrinolytic activity demonstrated by real-time imaging analysis2011
- Author(s)
  Suzuki, Y and Urano T
- Journal Title
  
  Journal Pharmacological Sciences
  
  Volume: 116(1) Pages: 19-24
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] コレステロールと抗血栓効果2011
- Author(s)
  鈴木優子、浦野哲盟
- Journal Title
  
  循環器内科
  
  Volume: 69(2) Pages: 170-176
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] In vivo imaging analysis of the interaction between unusually large von Willebrand factor multimers and platelets on the surface of vascular wall2011
- Author(s)
  Rybaltowski M, Suzuki Y, Mogami H, Chlebinska I, Brzoska T, Tanaka A, Banno F, Miyata T, Urano T
- Journal Title
  
  Pflugers Arch
  
  Volume: 461(6) Issue: 6 Pages: 623-33
- DOI
  10.1007/s00424-011-0958-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590826, KAKENHI-PROJECT-22790923, KAKENHI-PROJECT-23659494
[Journal Article] Life-threatening haemorrhage and prolonged wound healing are remarkable phenotypes manifested by complete PAI-1 deficiency in humans2011
- Author(s)
  Iwaki T, Tanaka A, Miyawaki Y, Suzuki A, Kobayashi T, Takamatsu J, Matsushita T, Umemura K, Urano T, Kojima T, Terao T, Kanayama N
- Journal Title
  
  Journal of Thrombosis and Haemostasis
  
  Volume: 9(6) Pages: 1200-1206
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] 血管内皮細胞上の線溶活性調節機構2011
- Author(s)
  鈴木優子
- Journal Title
  
  血液フロンティア
  
  Volume: 21 Pages: 1571-1579
- Data Source
  KAKENHI-PROJECT-22590826
[Journal Article] Life-threatening hemorrhage and prolonged wound healing are remarkable phenotypes manifested by complete plasminogen activator inhibitor-1 deficiency in humans2011
- Author(s)
  T Iwaki, A Tanaka, Y Miyawaki, A Suzuki, T Kobayashi, J Takamatsu, T Matsushita, K Umemura, T Urano, T Kojima, T Terao, N Kanayama
- Journal Title
  
  J Thromb Haemost
  
  Volume: 9(6) Issue: 6 Pages: 1200-1206
- DOI
  10.1111/j.1538-7836.2011.04288.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524, KAKENHI-PROJECT-22590826, KAKENHI-PROJECT-22591059, KAKENHI-PROJECT-22790247
[Journal Article] Surface-retained tPA is essential for effective fibrinolysis on vascular endothelial cells2011
- Author(s)
  Suzuki Y, Yasui H, Brzoska T, Mogami H, Urano T
- Journal Title
  
  Blood
  
  Volume: 118(11) Issue: 11 Pages: 3182-5
- DOI
  10.1182/blood-2011-05-353912
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590826
[Journal Article] In vivo imaging analysis of the interaction between unusually large von-Willebrand factor multimers and platelets on the surface of vascular wall2011
- Author(s)
  Rybaltowski M, Suzuki Y, Mogami H, Chlebinska I, Brzoska T, Tanaka A, Banno F, Miyata T, Urano T
- Journal Title
  
  Pflugers Arch-Eur J Physiol
  
  Volume: 461(6) Pages: 623-633
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] Novel Situations of Endothelial Injury in Stroke - Mechanisms of Stroke and Strategy of Drug Development: Novel Mechanism of the Expression and Amplification of Cell Surface-Associated Fibrinolytic Activity Demonstrated by Real-Time Imaging Analysis2011
- Author(s)
  Suzuki Y, Urano T
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 116 Issue: 1 Pages: 19-24
- DOI
  10.1254/jphs.10R23FM
- NAID
  10029893747
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590826
[Journal Article] 「技術講座」ユーグロブリンクロット溶解時間(Euglobulin Clot Lysis Time : ECLT)2011
- Author(s)
  浦野哲盟、柴山知子、鈴木優子
- Journal Title
  
  検査と技術
  
  Volume: 39(2) Pages: 86-92
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] Surface-retained tPA is essential for effective fibrinolysis on vascular endothelial cells2011
- Author(s)
  Suzuki Y, Yasui Y, Brzoska T, Mogami H, Urano T
- Journal Title
  
  Blood
  
  Volume: 118(11) Pages: 3182-3185
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] 線溶系検査の意味するところ2011
- Author(s)
  浦野哲盟, 鈴木優子
- Journal Title
  
  臨床病理
  
  Volume: 59(7) Pages: 703-708
- NAID
  10029615401
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] ユーグロブリンクロット溶解時間(Euglobulin Clot Lysis Time : ECLT)2011
- Author(s)
  浦野哲盟、柴山知子、鈴木優子
- Journal Title
  
  検査と技術
  
  Volume: 39(2) Pages: 86-92
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] 血管内皮細胞表面における滞留tPA惹起線溶活性増幅機構のイメージング解析2011
- Author(s)
  鈴木優子
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 22 Pages: 374-376
- NAID
  10031144655
- Data Source
  KAKENHI-PROJECT-22590826
[Journal Article] Novel situations of endothelial injury in stroke--mechanisms of stroke and strategy of drug development: novel mechanism of the expression and amplification of cell surface-associated fibrinolytic activitydemonstrated by real-time imaging analysis2011
- Author(s)
  Suzuki Y, Urano T
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 116(1) Pages: 19-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590826
[Journal Article] 抗血栓療法「凝固線溶系と血栓形成」2010
- Author(s)
  浦野哲盟, 鈴木優子
- Journal Title
  
  治療学
  
  Volume: 44(6) Pages: 17-20
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] GFP強発現ADAMTS13遺伝子欠損マウスの生体内イメージング解析2010
- Author(s)
  浦野哲盟, 鈴木優子, 最上秀夫, 坂野史明
- Journal Title
  
  血栓と循環
  
  Volume: 18(2) Pages: 4-7
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] A novel phospha sugar analogue : synthesis and evaluation of 2, 3-dibromo-3-methyl-1-phenylphospholane 1-oxide as a new class of potential panti-proliterative materials for leukemia cells2009
- Author(s)
  Fujie M, Nakamura S, Asai K, Niimi T, Yamashita J, Kiyofuji K, Shibata K, Suzuki M, Aoshima R, Urano T and Yamashita M
- Journal Title
  
  Heterocyclic Communications
  
  Volume: 15(4) Pages: 273-278
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] Inactivation of plasminogen activator inhibitor type 1 by activated factor XII plays a role in the enhancement of fibrinolysis by contact factors in-vitro2009
- Author(s)
  Tanaka A, Suzuki Y, Sugihara K, Kanayama N, Urano T.
- Journal Title
  
  Life Scineces 85(5/6)
  
  Pages: 220-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] Unique secretory dynamics of tissue plasminogen activator and its modulation by plasminogen activator inhibitor-lin vascular endothelial cells.2009
- Author(s)
  Suzuki Y
- Journal Title
  
  Blood 113
  
  Pages: 470-478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590858
[Journal Article] A technique for monitoring multiple signals with a combination of prism-based total internal reflection fluorescence microscopy and epifluorescence microscopy2009
- Author(s)
  Adachi E, Kazoe Y, Sato Y, Suzuki Y, Urano T, Ueyama T, Saito N, Nikolaev VO, Lohse MJ, Tominaga M, Mogami H
- Journal Title
  
  Pflugers Arch-Eur J Physiol
  
  Volume: 459(1) Pages: 227-34
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] Involvement of platelet activation by P2Y12 receptor in the development of transplant arteriosclerosis in mice2009
- Author(s)
  Yashiro K, Matsumoto Y, Ihara H, Suzuki Y, Kondo K, Urano T, Umemura K.
- Journal Title
  
  Transplantation 87 (3)
  
  Pages: 660-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] E A technique for monitoring multiple signals with a combination of prism-based total internal reflection fluorescence microscopy and epifluorescence microscopy2009
- Author(s)
  Adachi E, Kazoe Y, Sato Y, Suzuki Y, Urano T, Ueyama T, Saito N, Nikolaev VO, Lohse MJ, Tominaga M, Mogami H.
- Journal Title
  
  Pflugers Arch-Eur J Physiol 459(1)
  
  Pages: 227-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] Enhancement of fibrinolysis by gel-filtered platelets and its quenching by cytochalasin B and GPIIb/IIIa antagonists2009
- Author(s)
  Hoki S, Suzuki Y, Umemura K, Urano T
- Journal Title
  
  Pharmacological Reports
  
  Volume: 61(5) Pages: 877-84
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] Involvement of platelet activation by P2Y12 receptor in the development of transplant arteriosclerosis in mice2009
- Author(s)
  Yashiro K, Matsumoto Y, Ihara H, Suzuki Y, Kondo K, Urano T, Umemura K.
- Journal Title
  
  Transplantation 87(3)
  
  Pages: 660-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590858
[Journal Article] Unique secretory dynamics of tissue plasminogen activator and its modulation by plasminogen activator inhibitor-1 in vascular endothelial cells2009
- Author(s)
  Suzuki Y, Mogami H, Ihara Y, Urano T
- Journal Title
  
  Blood
  
  Volume: 113 Pages: 470-478
- NAID
  120005313162
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] Enhancement of fibrinolysis by gel-filtered platelets and its quenching by cytochalasin B and GPIIb/IIIa antagonists2009
- Author(s)
  Hoki S, Suzuki Y, Umemura K, Urano T.
- Journal Title
  
  Pharmacological Reports 61(5)
  
  Pages: 877-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] Inactivation of plasminogen activator inhibitor type 1 by activated factor XII plays a role in the enhancement of fibrinolysis by contact factors in-vitro2009
- Author(s)
  Tanaka A, Suzuki Y, Sugihara K, Kanayama N, Urano T
- Journal Title
  
  Life Scineces
  
  Volume: 85(5/6) Pages: 220-225
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] Unique secretory dynamics of tissue plasminogen activator and its modulation by plasminogen activator inhibitor-1 in vascular endothelial cells2009
- Author(s)
  Suzuki Y, Mogami H, Ihara Y, Urano T.
- Journal Title
  
  Blood 113
  
  Pages: 470-478
- NAID
  120005313162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590858
[Journal Article] Involvement of platelet activation by P2Y12 receptor in the development of transplant arteriosclerosis in mice2009
- Author(s)
  Yashiro K, Matsumoto Y, Ihara H, Suzuki Y, Kondo K, Urano T, Umemura K
- Journal Title
  
  Transplantation
  
  Volume: 87(3) Pages: 660-667
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] 血漿tPA及びPAI-1抗原量測定の意義-新たな知見からの再考察-2007
- Author(s)
  鈴木優子、浦野哲盟
- Journal Title
  
  日本血栓止血学会雑誌、18(3), 247-254, 2007 18(3)
  
  Pages: 247-254
- NAID
  10026114815
- Data Source
  KAKENHI-PROJECT-18590204
[Journal Article] 血漿 tPA 及びPAI-1抗原量測定の意義 -新たな知見からの再考察-2007
- Author(s)
  鈴木優子、浦野哲盟
- Journal Title
  
  日本血栓止血学会雑誌、18(3), 247-254, 2007 18(3)
  
  Pages: 247-254
- NAID
  10026114815
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590204
[Journal Article] 血漿tPA及びPAI-1抗原量測定の意義-新たな知見からの再考察-2007
- Author(s)
  鈴木優子、浦野哲盟
- Journal Title
  
  日本血栓止血学会雑誌 18(3)
  
  Pages: 247-254
- NAID
  10026114815
- Data Source
  KAKENHI-PROJECT-19590858
[Journal Article] Glucagon-Like Peptide 1 Activates Protein Kinase C Through a Ca^<2+>-Dependent Phospholipase C Activation in Insulin-Secreting Cells2006
- Author(s)
  Suzuki Y, Urano T, Zhang H, Saito N, Kojima N, Mogami H
- Journal Title
  
  Journal of Biological Chemistry 281・39
  
  Pages: 28499-28507
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590204
[Journal Article] In vivo imaging analysis of the interaction between unusually large von-Willebrand factor multimers and platelets on the surface of vascular wall.
- Author(s)
  Rybaltowski M, Suzuki Y, Mogami H, Chlebinska I, Brzoska T, Tanaka A, Banno F, Miyata T, Urano T
- Journal Title
  
  Pflugers Arch-Eur J Physiol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] A novel phospha sugar analogue : synthesis and evaluation of 2,3-dibromo-3-methyl-1-phenylphospholane 1-oxide as a new class of potential panti-proliterative materials for leukemia cells
- Author(s)
  Fujie M, Nakamura S, Asai K, Niimi T, Yamashita J, Kiyofuji K, Shibata K, Suzuki M, Aoshima R, Urano T, Yamashita M
- Journal Title
  
  Heterocyclic Communications (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] Novel mechanism of the expression and amplification of cell surface-associated fibrinolytic activity demonstrated by real-time imaging analysis.
- Author(s)
  Suzuki, Y, Urano T
- Journal Title
  
  Journal Pharmacological Sciences
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590230
[Journal Article] Life-threatening haemorrhage and prolonged wound healing are remarkable phenotypes manifested by complete PAI-1 deficiency in humans.
- Author(s)
  Iwaki T, Tanaka A, Miyawaki Y, Suzuki A, Kobayashi T, Takamatsu J, Matsushita T, Umemura K, Urano T, Kojima T, Terao T, Kanayama N.
- Journal Title
  
  Journal of Thrombosis and Haemostasis
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590230
[Patent] 血漿中線溶抵抗性活性の簡易評価法2022
- Inventor(s)
  Yuko Suzuki, Tetsumei Urano
- Industrial Property Rights Holder
  浜松医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-23K24431
[Patent] 血漿中線溶抵抗性活性の評価方法2022
- Inventor(s)
  鈴木優子、浦野哲盟
- Industrial Property Rights Holder
  浜松医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-22K08153
[Patent] 血漿中線溶抵抗活性の評価方法2021
- Inventor(s)
  鈴木優子、浦野哲盟
- Industrial Property Rights Holder
  国立大学法人浜松医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-177098
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19K08577
[Patent] plasminogen activator inhibitor type 1 の Gly397 近傍を標的とした活性阻害分子の発明2014
- Inventor(s)
  浦野哲盟、岩城孝行、鈴木優子、梅村和夫
- Industrial Property Rights Holder
  国立大学法人浜松医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-02-06
- Data Source
  KAKENHI-PROJECT-25461123
[Patent] plasminogen activator inhibitor type 1 の Gly397 近傍を標的とした活性阻害分子の発明2014
- Inventor(s)
  浦野哲盟、岩城孝行、鈴木優子、梅村和夫
- Industrial Property Rights Holder
  国立大学法人浜松医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-021457
- Filing Date
  2014-02-06
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Different impacts of direct thrombin inhibitor and factor Xa inhibitor on activated platelet-initiated plasma clot formation and lysis.2024
- Author(s)
  Yuko Suzuki et al.
- Organizer
  日本生理学会第101回記念大会
- Data Source
  KAKENHI-PROJECT-22K08153
[Presentation] COVID19と血栓止血障害：AMED 委託研究の結果報告を中心として2024
- Author(s)
  浦野哲盟、鈴木優子、森下英理子、本多政夫、木村英晴、堀内久徳、井上克枝、小亀浩市、川島祐介、安本篤史、渥美達也、福原崇介、保田晋助、仲瀬裕志
- Organizer
  日本血栓止血学会標準化委員会シンポジウム
- Data Source
  KAKENHI-PROJECT-23K24431
[Presentation] 新規指定難病申請疾患「出血性線溶異常症」の診断基準について2024
- Author(s)
  鈴木優子　他
- Organizer
  第18回日本血栓止血学会学術標準化委員会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22K08153
[Presentation] PAI-1欠損によるプラスミン活性亢進血管内皮細胞動態について2023
- Author(s)
  佐野秀人, 伊藤昌彦, 鈴木哲朗, 浦野哲盟, 鈴木優子
- Organizer
  日本血栓止血学会
- Data Source
  KAKENHI-PROJECT-23K24431
[Presentation] トロンボモジュリンの異なるドメインと濃度による抗凝固・抗線溶活性能の検討2023
- Author(s)
  鈴木優子, 望月里依奈, 佐野秀人, 諸岡七美, 浦野哲盟, 本藏直樹
- Organizer
  日本血栓止血学会
- Data Source
  KAKENHI-PROJECT-23K24431
[Presentation] プラスミン活性亢進による血管内皮細胞動態への影響について2023
- Author(s)
  佐野秀人 , 伊藤昌彦 , 鈴木哲朗 , 浦野哲盟 , 鈴木優子
- Organizer
  日本生理学会
- Data Source
  KAKENHI-PROJECT-23K24431
[Presentation] 抗凝固薬によるトロンビン活性の分布の変化がTAFIの活性化に影響を与える2023
- Author(s)
  鈴木優子　他
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08153
[Presentation] Coagulation activity-dependent regulation of fibrinolysis on activated platelets2023
- Author(s)
  鈴木優子　他
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-22K08153
[Presentation] 「COVID-19 associated coagulopathyと血栓止血関連検査」COVID-19における線溶活性の捉え方2023
- Author(s)
  鈴木優子　他
- Organizer
  第45回日本血栓止血学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08153
[Presentation] トロンボモジュリンの異なるドメインと濃度による抗凝固・抗線溶活性能の検討2023
- Author(s)
  鈴木優子　他
- Organizer
  第45回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08153
[Presentation] 「COVID-19 associated coagulopathyと血栓止血関連検査」 COVID-19における線溶活性の捉え方2023
- Author(s)
  鈴木優子, 長屋聡美, 森下英理子, 浦野哲盟
- Organizer
  日本血栓止血学会
- Data Source
  KAKENHI-PROJECT-23K24431
[Presentation] 生体顕微鏡を用いたレーザ惹起微小血栓溶解におけるcarboxypeptidase inhibitorの効果2022
- Author(s)
  鈴木優子、Nitty Mathws、佐野秀人、本藏直樹、浦野哲盟
- Organizer
  第44回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08577
[Presentation] Spatiotemporal Regulation of TAFI Activation, Plasminogen Activation, and Fibrinolysis by Thrombin.2022
- Author(s)
  Yuko Suzuki et al.
- Organizer
  Gordon Research Conference: Plasminogen Activation and Extracellular Proteolysis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08153
[Presentation] Spatiotemporal regulation of TAFI activation, plasminogen activation, and fibrinolysis by thrombin2022
- Author(s)
  Yuko Suzuki
- Organizer
  2022 Gordon Research Conference (GRC) on Plasminogen Activation and Extracellular Proteolysis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08577
[Presentation] Imaging analysis of cell-based regulation of fibrinolysis2022
- Author(s)
  Yuko Suzuki, Tetsumei Urano
- Organizer
  2022 Congress of International Society of Fibrinolysis and Proteolysis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24431
[Presentation] 生体顕微鏡を用いたレーザ惹起微小血栓溶解におけるcarboxypeptidase inhibitorの効果.2022
- Author(s)
  鈴木優子　他
- Organizer
  第44回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08153
[Presentation] Imaging analysis of cell-based regulation of fibrinolysis2022
- Author(s)
  Yuko Suzuki, Tetsumei Uranno
- Organizer
  The 3rd Joint Meeting of the International Society of Fibrinolysis and Proteolysis and the Plasminogen Activation Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08577
[Presentation] Real time imaging techniques illminate spatiotemporal regulation of fibrinolysis2021
- Author(s)
  鈴木優子
- Organizer
  第43回日本血栓止血学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08577
[Presentation] 活性化血小板による線維素溶解（線溶）抑制機構2021
- Author(s)
  鈴木優子、望月里衣奈、佐野秀人、本藏直樹、浦野哲盟
- Organizer
  第68回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-19K08577
[Presentation] Spatiotemporal regulation of fibrinolysis via thrombomodulin/thrombin/ TAFI system.2021
- Author(s)
  2.Yuko Suzuki, Hideto Sano, Naoki Honkura, Tetsumei Urano
- Organizer
  第43回日本血栓止血学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08577
[Presentation] 「教育講演」血栓形成溶解の時空間的制御2020
- Author(s)
  鈴木優子
- Organizer
  第82回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08577
[Presentation] 特別企画シンポジウム「次世代リーダーからのメッセージ」血栓形成-溶解機構の時空間的解析2020
- Author(s)
  鈴木優子
- Organizer
  第42回日本血栓止血学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08577
[Presentation] Spatiotemporal regulation of thrombin-activatable fibrinolysis inhibitor (TAFI) activation on activated platelets2020
- Author(s)
  Yuko Suzuki
- Organizer
  Gordon Research Conference; Plasminogen Activation and Extracellular Proteolysis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08577
[Presentation] Modulation of thrombin generation or thrombin activity on activated platelets surface largely affected TAFI-dependent regulation of fibrinolysis.2020
- Author(s)
  Suzuki Y, Sano H, Honkura N, Urano T
- Organizer
  The XXVII Congress of the International Society on Thrombosis and Hemostasis (ISTH),
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08577
[Presentation] トロンビンによるTAFIの活性化を介した線溶阻害作用のリアルタイムイメージング解析2020
- Author(s)
  鈴木優子，佐野秀人, 本藏直樹, 浦野哲盟
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08577
[Presentation] 血栓形成と溶解反応におけるクロストークの時空間的解析2020
- Author(s)
  鈴木優子
- Organizer
  第97回日本生理学会大会（誌上開催）
- Data Source
  KAKENHI-PROJECT-19K08577
[Presentation] Cell surface-modified fibrinolysis; contribution of vascular endothelial cells and platelets2019
- Author(s)
  Suzuki Y, Sano H, Honkura N, Urano T
- Organizer
  The 9th Federation of Asian and Oceanian Physiological Societies Congress (FAOPS2019) in conjunction with the 96th Annual Meeting of the Physiological Society of Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] thrombin-activatable fibrinolysis inhibitor活性化機構の時空間的解析2019
- Author(s)
  鈴木優子
- Organizer
  第41回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08577
[Presentation] 活性化血小板に基づく線溶反応の時空間的解析2019
- Author(s)
  鈴木優子
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08577
[Presentation] Platelet-dependent activation of thrombin-activatable fibrinolysis inhibitor (TAFI)2019
- Author(s)
  Yuko Suzuki
- Organizer
  The XXVII Congress of the International Society on Thrombosis and Haemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08577
[Presentation] Overview of the cross-talk between the coagulation-fibrinolysis System and cellular functions2019
- Author(s)
  Urano T, Suzuki Y
- Organizer
  The 9th Federation of Asian and Oceanian Physiological Societies Congress (FAOPS2019) in conjunction with the 96th Annual Meeting of the Physiological Society of Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] TAFI-dependent inhibition of fibrinolysis by platelets and vascular endothelial cells2018
- Author(s)
  Suzuki Y, Vidal M, Maess M, Sano H, Urano T.
- Organizer
  The 2nd Joint Meeting of ISFP and PA Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] Carbonylation makes fibrin resistant to fibrinolysis: its underlying mechanism and pathological implication.2018
- Author(s)
  Urano T, Sano H, Tanaka H, Suzuki Y
- Organizer
  The 2nd Joint Meeting of ISFP and PA Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] リジン残基のカルボニル化によるフィブリンの溶解抵抗性：修飾機構と生理的意義2018
- Author(s)
  浦野哲盟、佐野秀人、田中宏樹、鈴木優子
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] 線溶系による血栓形成制御と血栓症について2018
- Author(s)
  浦野哲盟、鈴木優子
- Organizer
  第50回日本動脈硬化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] Spatiotemporal analysis of membrane surface-based fibrinolysis on vascular endothelial cells and activated platelets2018
- Author(s)
  Suzuki Y, Sano H, Urano T
- Organizer
  The 10th Congress of Asia Pacific Society of Thrombosis and Hemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] Plasminogen Activator Inhibitor 1 (PAI-1) による線溶活性調節機構とその破綻に伴う病態発現2018
- Author(s)
  浦野哲盟、佐野秀人、田中宏樹、鈴木優子
- Organizer
  第28回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] Regulatory mechanism of the fibrinolytic activity and its related disorders2018
- Author(s)
  Urano T, Suzuki Y, Brzoska T, Sano H.
- Organizer
  2018 Congress on Open Issues in Thrombosis and Hemostasis together with the 9th Russian Conference on Clinical Hemostasiology and Hemorheology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] Vascular endothelial cells derived from human PAI-1 deficient iPS cells reveal physiological functions of PAI-1 in angiogenesis2017
- Author(s)
  Hideto Sano, Yuko Suzuki, Hiroki Tanaka, Takayuki Iwaki, Naohiro Kanayama, Tetsumei Urano
- Organizer
  26th International Society of Thrombosis and Hemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09411
[Presentation] Evaluation of activities of tissue-type plasminogen activators expressed and retained on vascular endothelial cells2016
- Author(s)
  鈴木優子、佐野秀人、田中宏樹、浦野哲盟
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25461123
[Presentation] Tip-cell like behavior in endothelial cells derived from human PAI-1 deficient iPS cells.2016
- Author(s)
  Sano H, Otsu M, Iwaki T, Nagahashi K, Tanaka H, Suzuki Y, Kanayama N, Urano T.
- Organizer
  第24回日本血管生物医学会学術集会
- Place of Presentation
  長崎
- Year and Date
  2016-12-08
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] Plasminogen Activator Inhibitor-1欠損患者iPS細胞由来内皮細胞の機能解析2016
- Author(s)
  佐野秀人、大津真、鈴木優子、田中宏樹、岩城孝行、Brzoska Tomasz、長橋ことみ、金山尚裕、浦野哲盟
- Organizer
  第63回中部日本生理学会
- Place of Presentation
  岡崎
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] 血管内皮細胞と活性化血小板の膜表面により惹起される線維素溶解反応のリアルタイムイメージング解析2016
- Author(s)
  鈴木優子、Brzoska Tomasz、佐野秀人、田中宏樹、浦野哲盟
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] Predominance of tip-cell like behavior in endothelial cells derived from human PAI-1 deficient iPS cells.2016
- Author(s)
  Sano H., Otsu M., Iwaki T., Nagahashi K., Tanaka H., Suzuki Y., Kanayama N., Urano T.
- Organizer
  The 1st Joint Meeting of ISFP and PA Workshop
- Place of Presentation
  Shizuoka Japan
- Year and Date
  2016-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09411
[Presentation] Real-time imaging analysis of membrane surface-triggered fibrinolysis on vascular endothelial cells and activated platelets2016
- Author(s)
  鈴木優子、Brzoska Tomasz，田中宏樹、佐野秀人、浦野哲盟
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-25461123
[Presentation] Functional Analysis of inducible Pluripotent Stem Cell-derived Vascular Endothelial Cells from Plasminogen Activator Inhibitor-1 Deficient Patients.2016
- Author(s)
  Sano H., Otsu M., Iwaki T., Nagahashi K., Tanaka H., Suzuki Y., Kanayama N., Urano T.
- Organizer
  AHA ATVB/PVD Scientific Sessions 2016
- Place of Presentation
  Nashville TN USA
- Year and Date
  2016-05-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09411
[Presentation] ヒトPlasminogen Activator Inhibitor-1（PAI-1）欠損内皮細胞における血管新生の異常2016
- Author(s)
  佐野秀人、鈴木優子、田中宏樹、浦野哲盟、岩城孝行、金山尚裕、高野勝弘
- Organizer
  第21回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] Coagulation-dependent initiation of fibrinolysis takes place on the surface of activated platelets, and is taegeted by TAFI.2016
- Author(s)
  Brzoska T, Suzuki S, Suzuki Y, Sano H, Tomczyk M, Tanaka H, Urano T.
- Organizer
  The 1st Joint Meeting of ISFP and PA Workshop
- Place of Presentation
  静岡
- Year and Date
  2016-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] Functional Analysis of Inducible Pluripotent Stem Cell derived Vascular Endothelial Cells From Plasminogen Activator Inhibitor-1 Deficient Patients.2016
- Author(s)
  Sano H, Suzuki Y,Tanaka H,Iwaki T, Urano T.
- Organizer
  ATVB2016 Scientific Sessions
- Place of Presentation
  Nashville (USA)
- Year and Date
  2016-05-05
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] ヒトPAI-1の内皮間葉移行（EndMT）における機能について2016
- Author(s)
  佐野秀人、大津真、岩城孝行、伊熊ことみ、Tomas Brzoska、田中宏樹、鈴木優子、金山尚裕、浦野哲盟
- Organizer
  第28回日本血栓止血学会学術集会
- Place of Presentation
  奈良
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] Proinflammatory cytokines and matrix metalloproteinases produced by adventitial adipocytes promotes abdominal aortic aneurysm development.2016
- Author(s)
  Tanaka H, Suzuki Y, Sano H, Unnno N, Setou M, Urano T
- Organizer
  The 1st Joint Meeting of ISFP and PA Workshop
- Place of Presentation
  静岡
- Year and Date
  2016-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08492
[Presentation] 血管内皮の抗血栓機能のリアルタイムイメージング解析2015
- Author(s)
  鈴木優子
- Organizer
  第20回静岡健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Year and Date
  2015-10-30
- Invited
- Data Source
  KAKENHI-PROJECT-25461123
[Presentation] 血管内皮細胞表面におけるプラスミノゲンアクチベーター活性の評価2015
- Author(s)
  鈴木優子、佐野秀人、Tomczyk Martyna、Brzoska Tomasz、浦野哲盟
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25461123
[Presentation] Assessment of plasminogen activator activity on vascular endothelial cells2015
- Author(s)
  鈴木優子
- Organizer
  The 9th Aso International Meeting
- Place of Presentation
  南阿蘇
- Year and Date
  2015-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461123
[Presentation] 血管内皮細胞発現tPAによるプラスミン産生ならびに線溶の定量評価と変異型tPAの機能解析2015
- Author(s)
  鈴木優子、Brzoska Tomasz、佐野秀人、浦野哲盟
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25461123
[Presentation] 血管内皮細胞によるプラスミノゲンアクチベータ活性発現調節のリアルタイムイメージング解析2015
- Author(s)
  鈴木優子、佐野秀人、田中宏樹、Brzoska Tomasz、浦野哲盟
- Organizer
  第23回日本血管生物医学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2015-12-10
- Data Source
  KAKENHI-PROJECT-25461123
[Presentation] 血管内皮細胞における組織プラスミノゲンアクチベータの開口放出と細胞表面専用活性発現増幅機構の可視化解析2014
- Author(s)
  鈴木優子、佐野秀人、ブルゾスカ　トーマス、浦野哲盟
- Organizer
  第91回日本生理学会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Regulatory mechanism of the expression of plasmin activity on vascular endothelial cells revealed by imaging technique2014
- Author(s)
  Urano T, Suzuki Y, Iwaki T
- Organizer
  Gordon Research Conferences
- Place of Presentation
  Ventura, LA, USA
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Phosphatidylserine exposure on platelets'surface requires the binding to a rigid fibrin scaffold2014
- Author(s)
  Brzoska T, Suzuki Y, Sano H, Urano T
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  kyoto
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Visualizing plasmin on cell surfaces2014
- Author(s)
  Urano T., Yuko Suzuki
- Organizer
  60th Annual Meeting of Scientific & Standardization Committee of the ISTH
- Place of Presentation
  Milwaukee (USA)
- Year and Date
  2014-06-25
- Invited
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Visualizing plasmin on cell surfaces2014
- Author(s)
  Urano T, Suzuki Y
- Organizer
  60th Annual Meeting of Scientific & Standardization Committee of the ISTH
- Place of Presentation
  Milwaukee
- Year and Date
  2014-06-25
- Data Source
  KAKENHI-PROJECT-25461123
[Presentation] Generation of inducible pluripotent stem (iPS) cells from plasminogen activator inhibitor-1 deficient patient2013
- Author(s)
  Sano H, Otsu M, Iwaki T, Nagahashi K, Suzuki Y, Kanayama N, Urano T
- Organizer
  XIVth International Workshop on Molecular and Cellular Biology of Plasminogen Activation
- Place of Presentation
  University of Notre Dame
- Data Source
  KAKENHI-PROJECT-24591420
[Presentation] Real time imaging of plasminogen binding to platelet-rich micro-thrombus and its effective lysis by tPA infusion in vivo2013
- Author(s)
  Urano T, Tanaka A, Brzoska T, Suzuki Y
- Organizer
  XXIV Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Real time imaging of plasminogen accumulation in platelet-rich micro-thrombus and its effective lysis by tPA infusion in vivo2013
- Author(s)
  Tanaka A, Suzuki Y, Brzoska T, Sano H, Urano T
- Organizer
  XIV International Workshop Molecular and Cellular Biology of Plasminogen Activation
- Place of Presentation
  Univ. of Notre Dame (USA)
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Generation of inducible pluripotent stem(iPS)cells from plasminogen activator inhibitor-1 deficient patient2013
- Author(s)
  Sano H, Otsu M, Iwaki T, Nagahashi K, Suzuki Y, Kanayama N, Urano T
- Organizer
  XIV International Workshop Molecular and Cellular Biology of Plasminogen Activation
- Place of Presentation
  Univ. of Notre Dame (USA)
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] イメージング手技を用いた血管内皮細胞上での線溶活性に対するPAI-1阻害薬TM5275の効果の検討2013
- Author(s)
  安井秀樹、鈴木優子、佐野秀人、Brzoska Tomasz、須田隆文、千田金吾、段孝、宮田敏男、浦野哲盟
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形市
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Real time imaging analysis of secreted-tPA dependent fibrinolytic activity on vascular endothelial cell surface and its enhancement by newly synthesized PAI-1 inhibitor2013
- Author(s)
  Yasui H, Suzuki Y, Brzoska T, Sano H, Suda T, Dan T, Miyata T, Urano T
- Organizer
  XIV International Workshop Molecular and Cellular Biology of Plasminogen Activation
- Place of Presentation
  Univ. of Notre Dame (USA)
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] In vivo 微小局在血栓へのプラスミノーゲン集積の解析2013
- Author(s)
  浦野哲盟、Brzoska Tomasz、田中晶、佐野秀人、鈴木優子
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形市
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Phosphatidylserine exposure on platelets'surface upon binding to rigid fibrin scaffold2013
- Author(s)
  Brzoska T, Suzuki Y, Mogami H, Sano H, Urano T
- Organizer
  XXIV Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] PAI-1欠損症患者の半生2012
- Author(s)
  長橋ことみ, 岩城孝行, 宮脇由理, 鈴木敦夫, 小林隆夫,高松純樹, 松下正, 梅村和夫, 浦野哲盟, 小嶋哲人, 寺尾俊彦, 金山尚裕
- Organizer
  第34回日本血栓止血学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Accelerated fibrinolysis on vascular endothelial cells triggered by membrane-retained secreted tPA2012
- Author(s)
  Suzuki Y, Urano T
- Organizer
  21th International Congress on Fibrinolysis and Proteolysis
- Place of Presentation
  Brighton, England
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] 日本血管生物医学科ジョイントシンポジウム「血管と血液のインターフェイス」:血管内皮細胞による線溶反応の時空間的制御2012
- Author(s)
  鈴木優子
- Organizer
  第34回日本血栓止血学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590826
[Presentation] Phosphatidylserine exposure on platelets' surface upon binding to rigid fibrin scaffold.2012
- Author(s)
  Tomasz Brzoska, 鈴木優子、佐野秀人、浦野哲盟
- Organizer
  第17回　日本病態プロテアーゼ学会学術集会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Accelerated fibrinolysis on vascular endothelial cells triggered by membrane-retained secreted tPA2012
- Author(s)
  Suzuki Y
- Organizer
  21thInternational Congress on Fibrinolysis and Proteolysis
- Place of Presentation
  Brighton. England
- Data Source
  KAKENHI-PROJECT-22590826
[Presentation] Accelerated fibrinolysis on vascular endothelial cells triggered by membrane-retained secreted tPA2012
- Author(s)
  Yuko Suzuki
- Organizer
  21th International Congress on Fibrinolysis and Proteolysis
- Place of Presentation
  Brighton, England
- Data Source
  KAKENHI-PROJECT-22590826
[Presentation] 日本血管生物医学会ジョイントシンポジウム「血管と血液のインターフェース」：血管内皮細胞による線溶反応の時空間的制御2012
- Author(s)
  鈴木優子
- Organizer
  第34回日本血栓止血学会学術集会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-22590826
[Presentation] 活性化血小板表面へのプラスミノーゲンの特異結合と微小局壁在血栓への解析2012
- Author(s)
  浦野哲盟, 田中晶, ブルゾスカ・トーマス, 鈴木優子
- Organizer
  第34回日本血栓止血学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] 血管内皮細胞上の線溶活性発現ポテンシャル維持機構とその破綻2012
- Author(s)
  浦野哲盟、鈴木優子
- Organizer
  第17回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  浜松
- Invited
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Unique secretory mechanism of t-PA and the expression of fibrinolytic activity on vascular endothelial cells.2012
- Author(s)
  Suzuki Y
- Organizer
  XXIIIth Congress of International Society of thrombosis hemostasis
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590826
[Presentation] Unique secretory mechanism of t-PA and the expression of fibrinolytic activity on vascular endothelial cells2011
- Author(s)
  Suzuki Y, Urano T
- Organizer
  XXIIIth Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Kyoto
- Year and Date
  2011-07-28
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] 血管内皮細胞における細胞表面滞留 tpA におよる新たな細胞表面線溶活性発現調節機構2011
- Author(s)
  鈴木優子
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22590826
[Presentation] Spontaneous plasma clot lysis time assay revealed the importance of "coagulation-associated enhancement of fibrinolysis"2011
- Author(s)
  Urano T, Brzoska T, Suzuki Y
- Organizer
  57th Annual Meeting of Scientific & Standardization Committee of the ISTH
- Place of Presentation
  Kyoto Japan
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Membrane-retained secreted tPA triggers cell-associated fibrinolysis on vascular endothelial cells.血管内皮細胞における細胞表面滞留tPAによる新たな細胞表面線溶活性発現調節機構2011
- Author(s)
  Urano T, Suzuki Y
- Organizer
  第89回日本生理学会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Real time imaging of plasminogen binding to platelet-rich micro-thrombus in vivo2011
- Author(s)
  Urano T, Tanaka A, Suzuki Y, Brzoska T, Mogami H
- Organizer
  XXIIIth Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] 血管内皮細胞表面における線溶酵素活性発現-増幅機構2011
- Author(s)
  浦野哲盟, 鈴木優子
- Organizer
  第16回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Real time imaging of plasminogen binding to micro-thrombus in vivo2011
- Author(s)
  Urano T, Tanaka A, Brzoska T, Mogami H, Suzuki Y
- Organizer
  第19回血管生物医学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Mogami H Real time imaging of plasminogen binding to platelet-rich micro-thrombus in vivo2011
- Author(s)
  Urano T, Tanaka A, Suzuki Y, Brzoska T
- Organizer
  57th Annual Meeting of Scientific & Standardization Committee of the ISTH
- Place of Presentation
  Kyoto Japan
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] ECLT shows fibrinolytic potential to be determined by the balance between tPA and PAI-1. What we learned from PAI-1 deficient patients2011
- Author(s)
  Urano T, Suzuki Y
- Organizer
  57th Annual Meeting of Scientific & Standardization Committee of the ISTH
- Place of Presentation
  Kyoto Japan
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Unique secretory mechanism of tPA and expression of fibrinolytic activity on vascular endothelial cells2011
- Author(s)
  Suzuki Y, Urano T
- Organizer
  XXIIIth Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] ECLT shows fibrinolytic potential to be determined by the balance between tPA and PAI-1. What we learned from PAI-1 deficient patients2011
- Author(s)
  Urano T, Suzuki Y
- Organizer
  57th Annual Meeting of Scientific & Standardization Committee of the ISTH
- Place of Presentation
  Kyoto
- Year and Date
  2011-07-22
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Imaging analysis of the interaction between unusually large von-willebrand factor multimers and platelets on vascular endothelial cells in living animals2011
- Author(s)
  Brzoska T, Rybaltowski M, Suzuki Y, Mogami H, Chlebinska I, Tanaka A, Banno F, Miyata T, Urano T
- Organizer
  57th Annual Meeting of Scientific & Standardization Committee of the ISTH
- Place of Presentation
  Kyoto Japan
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] 血管内皮細胞における細胞表面滞留tPAによる新たな細胞表面線溶活性発現調節機構2011
- Author(s)
  鈴木優子
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22590826
[Presentation] Unique secretory mechanism of t-PA and the expression of fibrinolytic activity on vascular endothelial cells2011
- Author(s)
  Suzuki Y.
- Organizer
  XXIII Congress of ISTH
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590826
[Presentation] Spontaneous plasma clot lysis time assay revealed the importance of "coagulation-associated enhancement of fibrinolysis"2011
- Author(s)
  Urano T, Brzoska T, Suzuki Y
- Organizer
  XXIIIth Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Imaging analysis of the interaction between unusually large von-willebr and factor multimers and platelets on vascular endothelial cells in living animals2011
- Author(s)
  Brzoska T, Rybaltowski M, Suzuki Y, Mogami H, Chlebinska I, Tanaka A, Banno F, Miyata T, Urano T
- Organizer
  XXIIIth Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] 血管内皮細胞における細胞表面線溶活性発現機構のイメージング解析2010
- Author(s)
  鈴木優子
- Organizer
  第1回浜松医科学シンポジウム
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-22590826
[Presentation] Intra-vital analyses of plasminogen binding to platelet-rich micro-thrombus2010
- Author(s)
  Tanaka A, Suzuki Y, Urano T
- Organizer
  20th International Congress on Fibrinolysis and Proteolysis
- Place of Presentation
  Amsterdam(The Netherlands)
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] 生体内顕微鏡を用いた微小局在血栓へのプラスミノーゲンの集積の解析2010
- Author(s)
  田中晶, 鈴木優子, 浦野哲盟
- Organizer
  第33回日本血栓止血学会学術集会
- Place of Presentation
  鹿児島
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] In-vivo Imaging Analyses of Platelet Thrombus Formation2010
- Author(s)
  T.Urano, Y.Suzuki, H.Mogami
- Organizer
  The 6th Congress of Asia Pacific Society on Thrombosis and Haemostasis
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] In-vivo Imaging Analyses of Platelet Thrombus Formation2010
- Author(s)
  Urano T, Suzuki Y, Mogami H
- Organizer
  The 6th Congress of Asia Pacific Society on Thrombosis and Haemostasis
- Place of Presentation
  Bali(Indonesia)
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] 線溶系検査の意味するところ2010
- Author(s)
  浦野哲盟, 鈴木優子
- Organizer
  第57回日本臨床検査医学会学術集会
- Place of Presentation
  京王プラザ
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] 血管内皮細胞表面における線溶活性発現-増幅機構のイメージング解析2010
- Author(s)
  鈴木優子
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-22590826
[Presentation] 血栓溶解療法:安全域と治療域の分子指標2010
- Author(s)
  浦野哲盟, 鈴木優子
- Organizer
  第5回日本血栓止血学会学術標準化委員会シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Intra-vital analyses of plasminogen binding to platelet-rich micro-thrombus2010
- Author(s)
  A.Tanaka, Y.Suzuki, T.Urano
- Organizer
  20th International Congress on Fibrinolysis and Proteolysis
- Place of Presentation
  Boston
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Inactivation of PAI-1 by activated Factor XII plays a role in the contact phase dependent enhancement of fibrinolysis2009
- Author(s)
  A.Tanaka, Y.Suzuki, N.Kanayama, T.Urano
- Organizer
  XXIIth Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Boston (USA)
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Dynamics of Platelet-vessel Wall Interactions2009
- Author(s)
  Urano T, Rybaltowski M, Hayashi T, Suzuki Y, Mogami H.
- Organizer
  5th General Assembly Asian Hematology Association
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-19590858
[Presentation] Intra-vital imaging analysis of platelet adhesion to vascular wall in AD AMTS13 KO mice2009
- Author(s)
  Rybaltowski Miroslaw, 鈴木優子, 田中晶, 坂野史明, 宮田敏行, 浦野哲盟
- Organizer
  第32回日本血栓止血学会学術集会
- Place of Presentation
  北九州国際会議場
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Realtime imaging analysis of phosphatidylserine exposure on platelet thrombus using intra-vital confocal microscopy2009
- Author(s)
  T.Urano, M.Rybaltowski, T.Hayashi, Y.Suzuki, H.Mogami
- Organizer
  XXIIth Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Boston (USA)
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Unique secretory dynamics of tissue plasminogen activator and its mod ulation by plasminogen activator inhibitor-1 in vascular endothelial cells. ISTH2011 Memorial Award2009
- Author(s)
  鈴木優子, 浦野哲盟
- Organizer
  第32回日本血栓止血学会学術集会
- Place of Presentation
  北九州国際会議場
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] 血管内皮細胞における線溶活性化因子分泌動態のイメージング解析2009
- Author(s)
  鈴木優子, 浦野哲盟
- Organizer
  第56回中部日本生理学会
- Place of Presentation
  石川県立音楽堂 (金沢)
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Secretagogue-induced multiple signal cross-talk in insuline secreting cells2009
- Author(s)
  H.Mogami, E.Adachi, I.Kojima, N.Saito, Y.Suzuki, T.Urano
- Organizer
  the XXXVI International Congress of Physiological Sciences (IUPS2009)
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] 血漿溶解時間を用いた凝固に伴う線溶活性増強作用の解析2009
- Author(s)
  浦野哲盟, 田中晶, 鈴木優子
- Organizer
  第32回日本血栓止血学会学術集会
- Place of Presentation
  北九州国際会議場
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Secretary dynamics of tPA from vascular endothelial cells and its modification by PAI-12008
- Author(s)
  Suzuki Y, Urano T.
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590858
[Presentation] 血液及び血管内皮から見た血栓症リスクシンポジウム「深部静脈血栓症の病態生理とその予防」2008
- Author(s)
  浦野哲盟、鈴木優子、井原勇人、最上秀夫
- Organizer
  第85回日本生理学会
- Place of Presentation
  東京
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-18590204
[Presentation] 血管内皮細胞におけるtPAの開口放出とその活性発現2008
- Author(s)
  鈴木優子
- Organizer
  第31回日本血栓止血学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-19590858
[Presentation] 血管内皮細胞におけるtPA開口放出とその活性発現2008
- Author(s)
  鈴木優子, 浦野哲盟
- Organizer
  第31回日本血栓止血学会
- Place of Presentation
  大阪
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-19590858
[Presentation] Unique exocytotic dynamics of tissue plasminogen activator(tPA)from vascular endothelial cells(VECs)and its modification by PAI-12008
- Author(s)
  Suzuki Y, Urano T.
- Organizer
  The 5th Congress of the Asian-Pacific Society on Thrombosis and Haemostasis
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-19590858
[Presentation] Fibrinolytic activity on vascular endothelial cells : secretory dynamics of tPA and its modification by PAI-12008
- Author(s)
  Suzuki Y, Urano T.
- Organizer
  第6回血液・血管オルビス
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590858
[Presentation] シンポジウム『深部静脈血栓症の病態生理とその予防』血液及び血管内皮から見た血栓症リスク2008
- Author(s)
  浦野哲盟、鈴木優子、井原勇人、最上秀夫
- Organizer
  第85回日本生理学会
- Place of Presentation
  東京
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590858
[Presentation] 血液及び血管内皮から見た血栓症リスクシンポジウム「深部静脈血栓症の病態生理とその予防」2008
- Author(s)
  浦野哲盟、鈴木優子、井原勇人、最上秀夫
- Organizer
  第85回日本生理学会
- Place of Presentation
  東京
- Year and Date
  2008-03-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590204
[Presentation] 血液及び血管内皮から見た血栓症リスク2007
- Author(s)
  浦野哲盟、鈴木優子、井原勇人、最上秀夫
- Organizer
  第85回日本生理学会、シンポジウム『深部静脈血栓症の病態生理とその予防』
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590858
[Presentation] nique Secretors Dynamics of Tissue Plasminogen Activator(tPA)is Beneficial to Maintain Fibrinolytic Activity on Cell Surface2007
- Author(s)
  Suzuki Y, Ihara H, Mogami H, Urano T
- Organizer
  XIth International Workshop on Molecular & Cellular Biology of Plasminogen Activation
- Place of Presentation
  Stockholm
- Year and Date
  2007-06-17
- Data Source
  KAKENHI-PROJECT-18590204
[Presentation] Unique secretory Dynamics of Tissue Plasminogen Activator(tPA)Is Beneficial to Maintain Fibrinolytic Activity on Cell Surface2007
- Author(s)
  Suzuki Y, Ihara H, Mogami H, Urano T.
- Organizer
  XIth International Workshop on Molecular and Cellular Biology of Plasminogen Activation
- Place of Presentation
  Stockholm
- Year and Date
  2007-06-17
- Data Source
  KAKENHI-PROJECT-19590858
[Presentation] Modification by PAI-1 of slow exocytotic dynamics of tissue plasminogen activator(tPA)and its activity on vascular endothelial cells(VECS)2007
- Author(s)
  T. Urano, Y. Suzuki, H. Ihara, H. Mogami
- Organizer
  XXIth Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Geneva
- Year and Date
  2007-07-09
- Data Source
  KAKENHI-PROJECT-19590858
[Presentation] Unique Secretory Dynamics of Tissue Plasminogen Activator (tPA) is Beneficial to Maintain Fibrinolytic Activity on Cell Surface2007
- Author(s)
  Suzuki, Y., Ihara, H., Mogami, H., Urano, T
- Organizer
  XIth International Workshop on Molecular & Cellular Biology of Plasminogen Activation
- Place of Presentation
  Stockholm
- Year and Date
  2007-06-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590204
[Presentation] 接触因子によるPAI-1不活性化に伴う線溶活性増強機構2007
- Author(s)
  田中晶、鈴木優子、金山尚裕、浦野哲盟
- Organizer
  第30回日本血栓止血学会
- Place of Presentation
  志摩市
- Year and Date
  2007-11-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590204
[Presentation] Modification by PAI-1 of slow exocvtotic dynamics of tissue plasminogen activator (tPA) and its activity on vascular endothelial cells (VECS)2007
- Author(s)
  Urano, T., Suzuki, Y., Ihara, H., Mogami, H
- Organizer
  XXIth Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Geneva
- Year and Date
  2007-07-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590204
[Presentation] Modification by PAI-1 of slow exocytotic dynamics of tissue plasminogen activator(tPA)and its activity on vascular endothelial cells(VECS)2007
- Author(s)
  Urano T, Suzuki Y, Ihara H, Mogami H.
- Organizer
  XXIth Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Geneva
- Year and Date
  2007-07-09
- Data Source
  KAKENHI-PROJECT-18590204
[Presentation] nique Secretory Dynamics of Tissue Plasminogen Activator(tPA)is Beneficial to Maintain Fibrinolytic Activity on Cell Surface2007
- Author(s)
  Suzuki Y, Ihara H, Mogami H, Urano T
- Organizer
  XIth International Workshop on Molecular & Cellular Biology of Plasminogen Activation
- Place of Presentation
  Stockholm
- Year and Date
  2007-06-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590204
[Presentation] Modification by PAI-1 of slow exocytotic dynamics of tissue plasminogen activator (tPA)and its activity on vascular endothelial cells(VECS)2007
- Author(s)
  T.Urano, Y.Suzuki, H.Ihara, H.Mogami
- Organizer
  XXIth Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Geneva
- Year and Date
  2007-02-09
- Data Source
  KAKENHI-PROJECT-19590858
[Presentation] Unique secretory Dynamics of Tissue Plasminogen Activator (tPA)Is Beneficial to Maintain Fibrinolytic Activity on Cell Surface2007
- Author(s)
  Suzuki Y, Ihara H, Mogami H, Urano T.
- Organizer
  Xlth International Workshop on Molecular and Cellular Biology of Plasminogen Activation
- Place of Presentation
  Stockholm
- Year and Date
  2007-06-17
- Data Source
  KAKENHI-PROJECT-19590858
[Presentation] Modification by PAI-1 0f slow exocytotic dynamics of tissue plasminogen activator(tPA)and its activity on vascular endothelial cells(VECS)2007
- Author(s)
  Urano T, Suzuki Y, Ihara H, Mogami H.
- Organizer
  XXIth Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Geneva
- Year and Date
  2007-07-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590204
[Presentation] 生体内顕微鏡を用いた血栓形成時の血小板phosphatidylserine発現の時空間的調節機構の解析シンポジウム「脂質ダイナミズムによる血栓止血反応の制御」2007
- Author(s)
  林忠毅, 最上秀夫, 村上裕介, 鈴木優子、今野弘之, 浦野哲盟
- Organizer
  第30回日本血栓止血学会
- Place of Presentation
  志摩市
- Year and Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-18590204
[Presentation] 生体内顕微鏡を用いた血栓形成時の血小板phosphatidylserine発現の時空間的調節機構の解析シンポジウム「脂質ダイナミズムによる血栓止血反応の制御」2007
- Author(s)
  林忠毅, 最上秀夫, 村上裕介, 鈴木優子、今野弘之, 浦野哲盟
- Organizer
  第30回日本血栓止血学会
- Place of Presentation
  志摩市
- Year and Date
  2007-11-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590204
[Presentation] 開口放出過程の可視化により判明したtPA分子特有の分泌動態と酵素活性発現調節シンポジウム「細胞線溶の新展開」2006
- Author(s)
  鈴木優子、浦野哲盟
- Organizer
  第29回日本血栓止血学会
- Place of Presentation
  宇都宮
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590204
[Presentation] Kinetics of tissue plasminogen activator(tPA)exocytosis from endothelial cells and its modulation by PA inhibitor-1(PAI-1),2006
- Author(s)
  Urano T, Suzuki Y, Ihara H, Mogami H
- Organizer
  The 4th Asian-Pacific Congress on Thrombosis and Hemostasis
- Place of Presentation
  Suzhou, China
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590204
[Presentation] Plasminogen activator inhibitor 1 forms a stable non-acyl enzyme inhibitor complex with tissue plasminogen activator2006
- Author(s)
  T. Yamashita, Q. Dai, H. Ihara, Y. Suzuki, H. Mogami, T. Koide, F. J. Castellino and T. Urano
- Organizer
  18th Congress on Fibrinolysis & Proteolysis
- Place of Presentation
  San Diego
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590204
[Presentation] 全反射蛍光顕微鏡を用いた血管内皮細胞からの組織型プラスミノーゲンアクチベーター開口放出動態のリアルタイム解析2006
- Author(s)
  鈴木優子、井原隼人、浦野哲盟
- Organizer
  第14回日本血管生物医学会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590204
[Presentation] Phosphatidylserine exposure on platelets'surface requires the binding to a rigid fibrin scaffold
- Author(s)
  Tomasz Brzoska, Yuko Suzuki, Hideto Sano, Tetsumei Urano
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  Kyoto
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-25461123
[Presentation] Genenration and differentiation of inducible pluripotent stem (iPS) cells derived from plasminogen activator inhibitor-1 deficient patient
- Author(s)
  Sano H, Otsu M, Iwaki T, Nagahashi K, Suzuki Y, Kanayama N, Urano T
- Organizer
  22nd International Congress on Fibrinolysis and Proteolysis
- Place of Presentation
  フランス、マルセイユ
- Year and Date
  2014-07-06 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-24591420
[Presentation] Regulatory mechanism of fibrinolytic activity in plasma and on vascular endotherial cells(VECS):messages from congenital deficiency cases of plasminogen activator inhibitor Type1(PAI-1) in human
- Author(s)
  Urano T, Suzuki Y, Sano H, Iwaki T.
- Organizer
  The 8th Congress of Asia Pacific Society of Thrombosis and Hemostasis
- Place of Presentation
  Hanoi
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-25461123
[Presentation] 生体内顕微鏡による微小血栓形成とプラスミノーゲン集積の解析
- Author(s)
  浦野哲盟, 田中晶, トーマスブルゾスカ, 鈴木優子, 最上秀夫
- Organizer
  第88回日本生理学会大会
- Place of Presentation
  震災により誌上開催
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] lasminogen Activator Inhibitor-1欠損患者からのiPS細胞樹立
- Author(s)
  佐野秀人、大津真、岩城孝行、長橋ことみ、鈴木優子、金山尚弘、浦野哲盟
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-30 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Generation of inducible pluripotent stem(iPS)cells from plasminogen activator inhibitor-1 deficient patient and differetiation into endothelial cells
- Author(s)
  Hideto Sano, Makoto Otsu, Takayuki Iwaki, Kotomi Nagahashi,Yuko Suzuki, Naohiro Kanayama, Tetsumei Urano
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  Kyoto
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-25461123
[Presentation] Phosphatidylserine exposure on platelets'surface requires the binding to a rigid fibrin scaffold.
- Author(s)
  Tomasz Brzoska, Yuko Suzuki, Hideto Sano, Tetsumei Urano
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  Kyoto
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] PAI-1欠損患者由来iPS細胞を用いた血管内皮細胞機能の解析
- Author(s)
  佐野秀人、大津真、岩城孝行、長橋ことみ、Brzoska Tomasz 、鈴木優子、金山尚裕、浦野哲盟
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府市
- Year and Date
  2015-05-21 – 2015-05-23
- Data Source
  KAKENHI-PROJECT-24591420
[Presentation] Post exocytotic- and cell surface retained- tissue plasminogen activator efficiently initiates fibrin clot lysis on vascular endothelial cells
- Author(s)
  Suzuki Y
- Organizer
  第8回 Aso International Meeting (AIM)
- Place of Presentation
  阿蘇
- Data Source
  KAKENHI-PROJECT-25461123
[Presentation] Generation of inducible pluripotent stem (iPS) cells from plasminogen activator inhibitor-1 deficient patient and differentiation into endothelial cells
- Author(s)
  Sano H, Otsu M, Iwaki T, Nagahashi K, Suzuki Y, Kanayama N, Urano T
- Organizer
  18th International Vascular Biology Meeting
- Place of Presentation
  京都市
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-24591420
[Presentation] リアルタイムイメージイングによる修飾tPAの分泌動態解析
- Author(s)
  鈴木優子　佐野秀人、Tomasz Brzoska、浦野哲盟
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-30 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Endogenously Generated Plasmin at the Vascular Wall Injury Site Amplifies Lysine Binding Site-Dependent Plasminogen Accumulation in Microthrombi.
- Author(s)
  Brzoska Tomasz, Tanaka-Murakami Aki, Suzuki Yuko, Sano Hideto, Kanayama Naohiro, Urano Tetsumei
- Organizer
  第61回中部日本生理学会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-07 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Generation and differentiation of inducible pluripotent stem(IPS)cells derived from plasminogen activator inhibitor-1 deficient patient.
- Author(s)
  Sano Hideto, Otsu Makoto, Iwaki Takayuki, Nagahashi Kotomi, Suzuki Yuko, Kanayama Naohiro, Urano Tetsumei
- Organizer
  22ND International Congress On Fibrinolysis ＆ Proteolysis
- Place of Presentation
  Marseille
- Year and Date
  2014-07-06 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-25461123
[Presentation] 本邦におけるPAI-1 欠損症の2例
- Author(s)
  浦野哲盟、伊熊ことみ、金山尚裕、高野勝弘、尾崎由基男、佐野秀人、鈴木優子、松下正、小嶋哲人、岩城孝行
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] Genenration and differentiation of iPS cells derived from plasminogen activator inhibitor-1 deficient patient
- Author(s)
  Sano H, Otsu M, Iwaki T, Nagahashi K, Brzoska T, Suzuki Y, Kanayama N, Urano T
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-24591420
[Presentation] Generation of inducible pluripotent stem(iPS)cells from plasminogen activator inhibitor-1 deficient patient and differetiation into endothelial cells.
- Author(s)
  Hideto Sano, Makoto Otsu, Takayuki Iwaki, Kotomi Nagahashi,Yuko Suzuki, Naohiro Kanayama, Tetsumei Urano
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  Kyoto
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] 血栓溶解療法:安全域と治療域の分子指標
- Author(s)
  浦野哲盟,鈴木優子
- Organizer
  第5回日本血栓止血学会学術標準化委員会シンポジウム
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Visualization of secretory dynamics of tissue-type plasminogen activator and cell surface-associated fibrinolytic activity on vascular endothelial cells
- Author(s)
  Suzuki Y
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学
- Invited
- Data Source
  KAKENHI-PROJECT-25461123
[Presentation] eneration and differentiation of inducible pluripotent stem(IPS)cells derived from plasminogen activator inhibitor-1 deficient patient.
- Author(s)
  Sano Hideto, Otsu Makoto, Iwaki Takayuki, Nagahashi Kotomi, Suzuki Yuko, Kanayama Naohiro, Urano Tetsumei
- Organizer
  22ND International Congress On Fibrinolysis ＆ Proteolysis
- Place of Presentation
  Marseille (France)
- Year and Date
  2014-07-06 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] 線溶系検査の意味するところ
- Author(s)
  浦野哲盟,鈴木優子
- Organizer
  第57回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-21590230
[Presentation] Regulatory mechanism of fibrinolytic activity in plasma and on vascular endotherial cells(VECS):messages from congenital deficiency cases of plasminogen activator inhibitor Type1(PAI-1) in human
- Author(s)
  Urano T, Suzuki Y, Sano H, Iwaki T.
- Organizer
  The 8th Congress of Asia Pacific Society of Thrombosis and Hemostasis
- Place of Presentation
  Hanoi (Vietnam)
- Year and Date
  2014-10-09 – 2014-10-11
- Invited
- Data Source
  KAKENHI-PROJECT-24590273
[Presentation] リアルタイムイメージイングによる修飾tPAの分泌動態解析
- Author(s)
  鈴木優子　佐野秀人、Tomasz Brzoska、浦野哲盟
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大坂
- Year and Date
  2014-05-30 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-25461123
[Presentation] Plasminogen Activator Inhibitor-1欠損患者からのiPS細胞樹立
- Author(s)
  佐野秀人、大津真、岩城孝行、長橋ことみ、鈴木優子、金山尚弘、浦野哲盟
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24591420

1. URANO Tetsumei (50193967)

# of Collaborated Projects: 15 results

# of Collaborated Products: 199 results
2. SANO Hideto (80623842)

# of Collaborated Projects: 11 results

# of Collaborated Products: 73 results
3. TANAKA Hiroki (50456563)

# of Collaborated Projects: 4 results

# of Collaborated Products: 22 results
4. Honkura Naoki (40518081)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. MOGAMI Hideo (90311604)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
6. 岩城孝行 (70509463)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
7. IHARA Hayato (00223298)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
8. WATANABE Hiroshi (50262803)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. YAMAMOTO Seiji (60144094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 諸岡七美 (40817110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 安井秀樹 (60804937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 須田隆文 (30291397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 乾直輝 (80402254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 小野孝明 (40402276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 今川孝太郎 (50366001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 高橋善明 (50647386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 吉野篤人 (90240332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 森下英理子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 本蔵直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results
20. 佐々木健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 小嶋哲人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 松下正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 熊田竜郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SUZUKI Yuko 鈴木 優子

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生体血管ライブイメージングにより解明する血栓形成溶解機構Principal Investigator

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Real-time imaging analysis of hemostatic thrombus stabilization and its failurePrincipal Investigator

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Understanding in spatio-temporal regulation mechanism of thrombus formation and dissolution for realization of appropriate antithrombotic therapyPrincipal Investigator

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Elucidation of intrinsic fibrinolytic activities potentiated vascular endothelial cells and its possibility in prophylaxis of thrombotic diseasePrincipal Investigator

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SUZUKI Yuko 鈴木優子