Furukawa Masayuki 古川正幸

… Alternative Names

古川正幸フルカワマサユキ

HURUKAWA Masayuki 古川正幸

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Researcher Number	20359524
Affiliation (Current)	2025: 順天堂大学, 医学部, 先任准教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 順天堂大学, 医学部, 先任准教授 2016: 順天堂大学, 医学部, 先任准教授 2007 – 2015: Juntendo University, 医学部, 准教授 2006 – 2007: 順天堂大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related Except Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related
Keywords	Principal Investigator 中耳炎 / 中耳粘膜肥厚 / JNK / 分子制御 / 急性中耳炎 / 中耳粘膜 / DNA microarray / 中耳腺細胞 / 好酸球性ムチン / 好酸球性中耳炎 … More / otitis media / mucosal hyperplasia / caspase / TUNEL / アポトーシス / 肥厚 / p38 / ｐ３８ / 細菌性中耳炎 / 癒着性中耳炎 / MAP kinase / JNK2 / JNK１ / 中耳炎モデル動物 / DNA array / Haemophilus influenza / Haemophilus influenzae … More Except Principal Investigator 内耳 / 骨破壊 / GJB2 / コルチ器 / Th17細胞 / 線維芽細胞 / 表皮細胞 / 真珠腫性中耳炎 / コネキシン26 / コンブィショナルKOマウス / iPS細胞 / マウス / ips細胞 / 遺伝性難聴 / メタロプロテアーゼ / 中耳真珠腫 / IL-17 / RANKL / SOD / カテプシン / ヒト中耳真珠腫 / アデノ随伴ウイル / アデノウイル / ウイルスベクター / 遺伝子導入 / GJB2遺伝子 / 聴性脳幹反応 / アデノ随伴ウイルスベクター / アデノウイルスベクター / 半規管 / 内リンパ / 蝸牛 / ノックアウトマウス / 難聴 / Cx26 / Deiter細胞 / Deiter細胞Cx26 / 柱細胞 / 細胞骨格 / 電子顕微鏡 / 遺伝子欠失 / 聴性脳幹反応検査 / 優性的阻害効果 / Gjb 遺伝子 / 先天聾 / Brn-4転写因子 / 先天性難聴 / 内耳の再生 / 再生 / 線維細胞 / Brn-4 Less

好酸球中耳炎における好酸球性ムチンの分泌応答とその制御Principal Investigator
- Principal Investigator
  
  古川正幸
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Juntendo University
Investigation of molecular mechanisms of middle ear cholesteatoma by the analysis of gene network involving bone destruction
- Principal Investigator
  
  haruyama takuo
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Juntendo University
p38 enhances middle ear proliferation during bacterial otitis mediaPrincipal Investigator
- Principal Investigator
  
  FURUKAWA Masayuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
The molecular mechanism of mucosal hypertrophy by JNK in middle earPrincipal Investigator
- Principal Investigator
  
  FURUKAWA MASAYUKI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
Promoter and inhibitor factors of bone destruction in human middle ear cholesteatoma
- Principal Investigator
  
  KUSUNOKI Takeshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
難聴遺伝子変異マウスへのiPS細胞移植による難聴レスキュウー
- Principal Investigator
  
  池田勝久
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
Cell therapy and gene therapy for heredity deafness with genetically modified mice
- Principal Investigator
  
  IKEDA Katuhisa
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
Molecular pathogenesis of middle ear mucosal proliferation during bacterial otitis mediaPrincipal Investigator
- Principal Investigator
  
  FURUKAWA Masayuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
Brn4による間葉系幹細胞からの蝸牛線維細胞への分化誘導と難聴の再生医学への応用
- Principal Investigator
  
  中澤詠子
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
Molecular basis of three-dimensional structure resolution using transgenic technology of deafness gene
- Principal Investigator
  
  IKEDA Katuhisa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
Therapy and molecular mechanisms of middle ear mucosal proliferation caused by apoptosis during bacterial otitis mediaPrincipal Investigator
- Principal Investigator
  
  FNRUKAWA Masayuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University

All 2021 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Association Between Earwax-Determinant Genotypes and Acquired Middle Ear Cholesteatoma in a Japanese Population2021
- Author(s)
  Hara Satoshi、Kusunoki Takeshi、Nakagawa Hiroshi、Toyoda Yu、Nojiri Shuko、Kamiya Kazusaku、Furukawa Masayuki、Takata Yusuke、Okada Hiroko、Anzai Takashi、Matsumoto Fumihiko、Ikeda Katsuhisa
- Journal Title
  
  Otolaryngology Head and Neck Surgery
  
  Volume: - Issue: 1 Pages: 139-145
- DOI
  10.1177/01945998211000374
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09356, KAKENHI-PROJECT-18K16858, KAKENHI-PROJECT-18K09388, KAKENHI-PROJECT-21K09566, KAKENHI-PROJECT-21K09589, KAKENHI-PROJECT-18K16857, KAKENHI-PROJECT-20K21662, KAKENHI-PROJECT-21H03089
[Journal Article] Expression of IL-17 and its role in bone destruction in human middle Ear cholesteatoma2010
- Author(s)
  Haruyama T, Furukawa M, Kusunoki T, Onoda J, Ikeda K
- Journal Title
  
  ORL
  
  Volume: 72 Pages: 325-331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592168
[Journal Article] A randomized prospective study of oral levofloxacin vs intravenous flomoxef prophylaxis in postoperative infection after endoscopic sinus surgery.2010
- Author(s)
  Inosita A, Yokoi H, Matsumoto F, Yao T, Kawano K Furukawa M, Ikeda K
- Journal Title
  
  Am J Otolaryngol. 31(5)
  
  Pages: 360-363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591992
[Journal Article] Expression of IL-17 and its role in bone destruction in human middle ear cholesteatoma.2010
- Author(s)
  Furukawa M, Kusunoki T, Onoda J, Ikeda K., Haruyama T
- Journal Title
  
  ORL J Otorhinolaryngol Relat Spec. 72(6)
  
  Pages: 325-331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591992
[Journal Article] Overexpression of GLUT-1 in the invasion front is associated with depth of oral squamous cell carcinoma and prognosis.2010
- Author(s)
  Ohba S, Fujii H, Ito S, Fujimaki, M, Matsumoto F, Furukawa M, Yokoyama J, Kusunoki T, Ikeda K, Hino O
- Journal Title
  
  J Oral Pathol Med. 39(1)
  
  Pages: 74-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591992
[Journal Article] Laryngeal stenosis in epidermolysis bullosa dystrophica.2009
- Author(s)
  Haruyama T, Furukawa M, Matsumoto F, Kawano K, Ikeda K
- Journal Title
  
  Auris Nasus Larynx. 36(1)
  
  Pages: 106-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591992
[Journal Article] Eotaxin-1, -2, and -3 immunoreactivity and protein concentration in the nasal polyps of eosinophilic chronic rhinosinusitis patients.2009
- Author(s)
  Yao T, Kojima Y, Koyanagi A, Yokoi H, Saito T, Kawano K, Furukawa M, Kusunoki T, Ikeda K
- Journal Title
  
  Laryngoscope 119
  
  Pages: 1053-9
- Data Source
  KAKENHI-PROJECT-20390445
[Journal Article] Development of distortion product Otoacoustic emissions in C57BL/6J mice2009
- Author(s)
  Narui Y, Minekawa A, Iizuka T, Furukawa M, Kusunoki T, Koike T, Ikeda K.
- Journal Title
  
  Int J Audiol 48
  
  Pages: 576-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390445
[Journal Article] Overexpression of GLUT-1 in the invasion front is associated with depth of oral squamous cell carcinoma and prognosis.2009
- Author(s)
  Ohba S, Fujii H, Ito S, Fujimaki M, Matsumoto F, Furukawa M, Yokoyama J, Kusunoki T, Ikeda K
- Journal Title
  
  Hino O J Oral Pathol Med.
- Data Source
  KAKENHI-PROJECT-20390445
[Journal Article] Eotaxin-1, -2, and-3 immunoreactivity and protein concentration in the nasal polyps of eosinophilic chronic rhinosinusitis patients.2009
- Author(s)
  Yao T, Kojima Y, Koyanagi A, Yokoi H, Saito T, Kawano K, Furukawa M, Kusunoki T, Ikeda K
- Journal Title
  
  Laryngoscope. 119(6)
  
  Pages: 1053-1059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591992
[Journal Article] Prevention of ultrasonic coagulator-mediated mucoperiosteal flap injury and defects by using a clip manipulation in the resection of the posterior nasal nerve.2009
- Author(s)
  Ikeda K, Yokoi H, Saito T, kawano K, Yao T, Furukawa M, Kusunoki T
- Journal Title
  
  Rhinology. 47(1)
  
  Pages: 45-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591992
[Journal Article] Development of distortion product otoacoustic emissions in C57BL/6J mice.2009
- Author(s)
  Narui Y, Minekawa A, Iizuka T, Furukawa M, Kusunoki T, Koike T, Ikeda K
- Journal Title
  
  Int J Audiol. 48(8)
  
  Pages: 576-581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591992
[Journal Article] Development of distortion product Otoacoustic emissions in C57BL/6J mice.2009
- Author(s)
  Narui Y, Minekawa A, Iizuka T, Furukawa M, Kusunoki T, Koike T, Ikeda K
- Journal Title
  
  Int J Audiol 48
  
  Pages: 576-81
- Data Source
  KAKENHI-PROJECT-20390445
[Journal Article] Postnasal development of the organ of Corti in dominant-negative Gjb2 transgenic mice.2008
- Author(s)
  Inoshita A, Iizuka T, Okamura HO, Minekawa A, Kojima K, Furukawa M, Kusunoki T, Ikeda K
- Journal Title
  
  Neuroscience. 156(4)
  
  Pages: 1039-1047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591992
[Journal Article] Clinical effectiveness of ototopical application of mupirocin ointment in methicillin-resistant Staphylococcus aureus otorrhea.2008
- Author(s)
  Furukawa M, Minekawa A, Haruyama T, Narui Y, Sugita G, Sugita R, Kusunoki T, Ikeda K
- Journal Title
  
  Otol Neurotol. 29(5)
  
  Pages: 676-678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591992
[Journal Article] Postnatal development of the organ of Corti in dominant-negative Gjb2 transgenic mice2008
- Author(s)
  Inoshita A, Iizuka T, Okamura HO, Minekawa A, Kojima K, Furukawa M, Kusunoki T, Ikeda K
- Journal Title
  
  Neuroscience 156
  
  Pages: 1039-1047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390445
[Journal Article] Noninvasive in vivo delivery of transgene via adeno-associated virus into supporting cells of the neonatal mouse cochlea2008
- Author(s)
  Iizuka T, Kanzaki S, Mochizuki H, Inoshita A, Narui Y, Furukawa M, Kusunoki T, Saji M, Ogawa K, Ikeda K
- Journal Title
  
  Hum Gene Ther 19
  
  Pages: 384-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390445
[Journal Article] Jun N-terminal protein kinase enhances middle ear mucosal proliferation during bacterial otitis media.2007
- Author(s)
  Furukawa M, Ebmeyer J, Pak K, Austin DA, Melhus A, Webster NJ, Ryan AF.
- Journal Title
  
  Infection and Immunity. 75
  
  Pages: 2562-2571
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591886
[Journal Article] Webster NJ, Eyan AF. Jun N-terminal protein kinase Jun Nterminal protein kinase enhances middle ear mucosal proliferation during bacterial otitis media.2007
- Author(s)
  Furukawa M, Ebmeyer J, Pak K, Austin DA, Melhus A
- Journal Title
  
  Infection and Immunity 75
  
  Pages: 2562-2571
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591886
[Journal Article] Jun N-terminal protein kinase enhances middle ear mucosal proliferation during bacterial otitis media2007
- Author(s)
  Furukawa M, Ebmeyer J, Pak K, Austin DA, Melhus A, Webster NJ, Ryan AF
- Journal Title
  
  Infection&Immunity 75
  
  Pages: 2562-2571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591886
[Presentation] 外耳道真珠腫と耳垢型　ABCC11遺伝子多型についての検討2021
- Author(s)
  岡田弘子, 楠威志, 原聡, 神谷和作, 高田雄介, 古川正幸, 池田勝久
- Organizer
  第31回日本耳科学会
- Data Source
  KAKENHI-PROJECT-18K09388
[Presentation] Surgical management of myringosclerosis over the whole tympanic membrane in simple underlay myringoplasty2009
- Author(s)
  Masayuki Furukawa, et al
- Organizer
  6^<th> extraordinary international symposium on recent advances in Otitis Media
- Place of Presentation
  Seoul
- Year and Date
  2009-05-07
- Data Source
  KAKENHI-PROJECT-20591992

1. IKEDA Katuhisa (70159614)

# of Collaborated Projects: 8 results

# of Collaborated Products: 17 results
2. KUSUNOKI Takeshi (30248025)

# of Collaborated Projects: 8 results

# of Collaborated Products: 16 results
3. KAMIYA Kazusaku (10374159)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. YOKOI Hidenori (80317487)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
5. KASAI Misato (70549279)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 岡田弘子 (20433774)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MINOWA Osamu (00181967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KOIKE Takuji (10282097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. KAKEHATA Seiji (90261619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MATTUMOTO Fumihiko (70445584)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. haruyama takuo (80549270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 中澤詠子 (60245751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NAKAGAWA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 豊田優

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Furukawa Masayuki 古川 正幸

古川 正幸 フルカワ マサユキ

HURUKAWA Masayuki 古川 正幸

Research Projects

Research Products

Co-Researchers

好酸球中耳炎における好酸球性ムチンの分泌応答とその制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of molecular mechanisms of middle ear cholesteatoma by the analysis of gene network involving bone destruction

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

p38 enhances middle ear proliferation during bacterial otitis mediaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The molecular mechanism of mucosal hypertrophy by JNK in middle earPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Promoter and inhibitor factors of bone destruction in human middle ear cholesteatoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

難聴遺伝子変異マウスへのiPS細胞移植による難聴レスキュウー

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cell therapy and gene therapy for heredity deafness with genetically modified mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular pathogenesis of middle ear mucosal proliferation during bacterial otitis mediaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Brn4による間葉系幹細胞からの蝸牛線維細胞への分化誘導と難聴の再生医学への応用

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular basis of three-dimensional structure resolution using transgenic technology of deafness gene

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Therapy and molecular mechanisms of middle ear mucosal proliferation caused by apoptosis during bacterial otitis mediaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Association Between Earwax-Determinant Genotypes and Acquired Middle Ear Cholesteatoma in a Japanese Population2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of IL-17 and its role in bone destruction in human middle Ear cholesteatoma2010

Author(s)

Journal Title

Furukawa Masayuki 古川正幸

古川正幸フルカワマサユキ

HURUKAWA Masayuki 古川正幸