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OKU Naohisa  奥 尚久

ORCIDConnect your ORCID iD *help
Researcher Number 20363286
Affiliation (based on the past Project Information) *help 2003 – 2005: Kochi Medical School, Department of Oral Surgery, Research Associate, 医学部附属病院, 助手
Review Section/Research Field
Principal Investigator
Pathobiological dentistry/Dental radiology
Except Principal Investigator
Surgical dentistry / 病態科学系歯学(含放射線系歯学)
Keywords
Principal Investigator
Metastasis / Invasion / Laminin-5 γ2 chain / Claudin-1 / Tight junction / MMP-2 / Laminin-5 γ2鎖 / siRNA / 口腔扁平上皮癌 / 転移 … More / 浸潤 / Laminin-5γ2鎖 / クローディン / タイトジャンクション … More
Except Principal Investigator
Mn-SOD / Peptide 2 / β-catenin / claudin / occludin / tight junction / reactive oxygen species / invasion / oral cancer / 活性酵素 / β-カテニン / クラウジン / オクルジン / タイトジャンクション / 活性酸素 / 浸潤 / 口腔癌 / neutrophils / aspergillosis / candidiasis / cytochrome P450 / β-defensin / α-defensin / antimicrobial peptide / カンジタ症 / チトクロームp450 / Peptide2 / 好中球 / アスペルギルス症 / カンジダ症 / チトクロームP450 / β-ディフェンシン / α-ディフェンシン / 抗菌ペプタイド Less
  • Research Projects

    (3 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (7 People)
  •  Attempt of suppression of oral cancer invasion by overexpression of tight and adherens junction constitution proteinsPrincipal Investigator

    • Principal Investigator
      OKU Naohisa
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Kochi University
  •  Biological investigation of antimicrobial peptides for the regulation of fungal infections

    • Principal Investigator
      UETA Eisaku
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Kochi Medical School
  •  Basic investigation on moledules which regulate the sensitivity of oral squamous cell carcinoma (cells) to chemo-radio-immunotherapy

    • Principal Investigator
      OSAKI Tokio
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kochi Medical School

All 2006 Other

All Journal Article

  • [Journal Article] Tight Junction Protein Claudin-1 Enhances the Invasive Activity of Oral Squamous Cell Carcinoma Cells by Promoting Cleavage of Laminin-5γ2 Chain via Matrix Metalloproteinase-2 and Membrance-type Matrix Metalloproteinase-12006

    • Author(s)
      奥 尚久
    • Journal Title

      Cancer Research 60・10

      Pages: 5251-5257

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591886
  • [Journal Article] Tight junction protein claudin-1 enhances the invasive activity of oral squamous cell carcinoma cells by promoting cleavage of laminin-5 γ2 chain via matrix metalloproteinase-2 and membrane-type matrix metallo-proteinase-12006

    • Author(s)
      NAOHISA OKU
    • Journal Title

      Cancer Research 60-10

      Pages: 5251-5257

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591886
  • [Journal Article] Tight junction protein claudin-1 enhances the invasive activity of oral squamous cell carcinoma cells by promoting cleavage of laminin-5 γ2 chain via matrix metalloproteinase-2 and membrane-type matrix metalloproteinase-1

    • Author(s)
      奥 尚久
    • Journal Title

      Cancer Research (印刷中)

    • Data Source
      KAKENHI-PROJECT-16591886
  • 1.  UETA Eisaku (10203431)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  KAMATANI Takaaki (00315003)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  SASABE Eri (40363288)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  YAMAMOTO Tetsuya (00200824)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  OSAKI Toki (70031995)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  木村 剛 (10294836)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  立石 善久 (20372732)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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