Yamada Hisakata 山田久方

… Alternative Names

山田久方ヤマダヒサカタ

YAMADA Hisakata 山田久方

Less

Researcher Number	20363369
Other IDs
Affiliation (Current)	2025: 九州大学, 医学研究院, 特任准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 九州大学, 医学研究院, 准教授 2018: 九州大学, 医学研究院, 共同研究員 2016 – 2017: 九州大学, 生体防御医学研究所, 共同研究員 2015: 九州大学, 生体防御医学研究所, 研究員 2008 – 2014: Kyushu University, 生体防御医学研究所, 准教授 … More 2009: 九州大学, 生医研, 准教授 2007: 九州大学, 成体防衛医学研究院, 准教授 2005 – 2006: 九州大学, 生体防御医学研究所, 助教授 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related / 膠原病・アレルギー・感染症内科学 Except Principal Investigator Orthopaedic surgery / Bacteriology (including Mycology) / Thoracic surgery
Keywords	Principal Investigator 関節リウマチ / サイトカイン / T細胞 / リウマチ病学 / 滑膜 / マクロファージ / 免疫学 / リウマチ学 / B細胞 / 実験的関節炎 … More / 自己抗体 / ヘルパーT細胞 / マウス / 関節炎 … More Except Principal Investigator 薬剤反応性 / マイクロアレイ / トランスレーショナルリサーチ / 癌 / 負の選択 / γインターフェロン / キラー活性 / リステリア感染 / HY特異性CD8T細胞 / IL-15 / IL-2 / 腸内細菌 / 炎症性腸疾患 / IL-17 / CD301 / 自然免疫T細胞 / IL-12/IL-15 / 感染防禦 / IFN-gamma / Listeria monocytogenes / CD30L / 自然免疫CD4+T細胞 / 感染免疫 / 免疫寛容 / 免疫寛容誘導 / サイクロフォスファミド / キメリズム / 関節破壊 / 骨吸収 / 関節リウマチ / 慢性炎症 / ナノテクノロジー Less

滑膜常在マクロファージを中心とした関節炎症病態の解析Principal Investigator
- Principal Investigator
  
  山田久方
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kyushu University
Elucidating the pathogenic roles of CD4T cells in rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  Hisakata Yamada
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyushu University
悪性骨軟部腫瘍における薬剤耐性獲得機構の解明
- Principal Investigator
  
  岩本幸英
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyushu University
Investigating T cells helping autoantibody production in rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  YAMADA Hisakata
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kyushu University
The roles of innate T cells in bacterial infection
- Principal Investigator
  
  YOSHIKAI Yasunobu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kyushu University
Experimental organ transplantation: Application of the drug-induced immune tolerance-
- Principal Investigator
  
  TOMITA Yukihiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kyushu University
Regulation of immune responses by IL-15Principal Investigator
- Principal Investigator
  
  HISAKATA Yamada
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyushu University
Development of Nano-treatment for musculoskeletal chronic inflammation
- Principal Investigator
  
  NAKASHIMA Yasuharu
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyushu University
関節炎症性疾患における新規サイトカインレセプターWSX-1の役割Principal Investigator
- Principal Investigator
  
  山田久方
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyushu University

All 2024 2022 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Synovial-tissue resident macrophages play proinflammatory functions in the pathogenesis of RA while maintaining the phenotypes in the steady state2024
- Author(s)
  Kai Kazuhiro、Yamada Hisakata、Tsurui Ryosuke、Sakuraba Koji、Fujimura Kenjiro、Kawahara Shinya、Akasaki Yukio、Tsushima Hidetoshi、Fujiwara Toshifumi、Hara Daisuke、Fukushi Jun-ichi、Sawa Shinichiro、Nakashima Yasuharu
- Journal Title
  
  Immunological Medicine
  
  Volume: - Issue: 2 Pages: 1-10
- DOI
  10.1080/25785826.2023.2300853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16723, KAKENHI-PROJECT-20K22989, KAKENHI-PROJECT-22K09359, KAKENHI-PROJECT-22K09382
[Journal Article] T cells specific for post-translational modifications escape intrathymic tolerance induction2018
- Author(s)
  Raposo B, Merky P, Lundqvist C, Yamada H, Urbonaviciute V, Niaudet C, Viljanen J, Kihlberg J, Kyewski B, Ekwall O, Holmdahl R, Backlund J
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 353-353
- DOI
  10.1038/s41467-017-02763-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10907
[Journal Article] Th1 is the predominant helper T cell subset that produces GM-CSF in the joint of rheumatoid arthritis.2017
- Author(s)
  Yamada H, Haraguchi A, Sakuraba K, Okazaki K, Fukushi JI, Mizu-Uchi H, Akasaki Y, Esaki Y, Kamura S, Fujimura K, Kondo M, Miyahara H, Nakashima Y, Yoshikai Y.
- Journal Title
  
  RMD Open
  
  Volume: 3 Issue: 1 Pages: e000487-e000487
- DOI
  10.1136/rmdopen-2017-000487
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10907, KAKENHI-PLANNED-16H06496
[Journal Article] Activation of the Akt-mTOR and MAPK pathways in dedifferentiated liposarcomas2016
- Author(s)
  Ishii T, Kohashi K, Iura K, Maekawa A, Bekki H, Yamada Y, Yamamoto H, Nabeshima K, Kawashima H, Iwamoto Y, Oda Y
- Journal Title
  
  Tumor Biology
  
  Volume: 37(4) Issue: 4 Pages: 4767-4776
- DOI
  10.1007/s13277-015-4232-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293325, KAKENHI-PROJECT-25293088, KAKENHI-PROJECT-26460435
[Journal Article] Elevated Expression of HSP90 and the Antitumor Effect of an HSP90 Inhibitor via Inactivation of the Akt/mTOR Pathway in Undifferentiated Pleomorphic Sarcoma2015
- Author(s)
  Bekki H, Kohashi K, Maekawa A , Yamada Y, Yamamoto H, Harimaya K, Hakozaki M, Nabeshima K, Iwamoto Y, Oda Y
- Journal Title
  
  BMC Cancer
  
  Volume: 15.804 Pages: 1-11
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293325
[Journal Article] Cancer-testis antigen PRAME and NY-ESO-1 correlates with tumor grade and poor prognosis in myxoid/round cell liposarcoma2015
- Author(s)
  Iura K, Kohashi K, Ishii T, Maekawa A, Yamada Y, Hotokebuchi Y, Yamamoto H, Iwamoto Y, Oda Y
- Journal Title
  
  J Pathol Clin Pract
  
  Volume: 1(3) Issue: 3 Pages: 144-159
- DOI
  10.1002/cjp2.16
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293325
[Journal Article] Successful in vitro culture of synovial explants from rheumatoid arthritis at the air-liquid interface.2015
- Author(s)
  Sakuraba K, Fujimura K, Nakashima Y, Okazaki K, Fukushi JI, Ohishi M, Oyamada A, Esaki Y, Miyahara H, Iwamoto Y, Yoshikai Y, Yamada H.
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: 67 Issue: 4 Pages: 881-892
- DOI
  10.1002/art.39019
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591449, KAKENHI-PROJECT-24791552, KAKENHI-PROJECT-15K20023, KAKENHI-PROJECT-15K20006
[Journal Article] Malignant solitary fibrous tumor with high-grade nuclear atypia: an alternate entity for the undetermined tumor group.2015
- Author(s)
  Yamada Y, Kohashi K; Bekki H, Ishii T, Iura K, Maekawa A, Yamamoto H, Iwamoto Y, Oda Y
- Journal Title
  
  Pathol Res Pract
  
  Volume: 211(2) Issue: 2 Pages: 117-124
- DOI
  10.1016/j.prp.2014.12.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293088, KAKENHI-PROJECT-25293325, KAKENHI-PLANNED-26108010
[Journal Article] ERG and SALL4 expressions in SMARCB1/INI1-deficient tumors: a useful tool for distinguishing epithelioid sarcoma from malignant rhabdoid tumor.2015
- Author(s)
  Kohashi K, Yamada Y, Hotokebuchi Y; Yamamoto H, Taguchi T, Iwamoto Y, Oda Y
- Journal Title
  
  Hum Pathology
  
  Volume: 46(2) Issue: 2 Pages: 225-230
- DOI
  10.1016/j.humpath.2014.10.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293088, KAKENHI-PROJECT-25293325, KAKENHI-PROJECT-26460435, KAKENHI-PROJECT-26462708
[Journal Article] Differential microRNA expression profiles between malignant rhabdoid tumor and epithelioid sarcoma: miR193a-5p is suggested to downregulate SMARCB1 mRNA expression.2014
- Author(s)
  Kohashi K, Yamamoto H, Kumagai R, Yamada Y, Hotokebuchi Y, Taguchi T, Iwamoto Y, Oda Y.
- Journal Title
  
  Mod Pathol
  
  Volume: 未定 Issue: 6 Pages: 832-839
- DOI
  10.1038/modpathol.2013.213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24790352, KAKENHI-PROJECT-25293325
[Journal Article] Activation of the Akt-mTOR pathway and receptor tyrosine kinase in patients with solitary fibrous tumors.2014
- Author(s)
  Yamada Y, Kohashi K, Fushimi F, Takahashi Y, Setsu N, Endo M, Yamamoto H, Tokunaga S, Iwamoto Y, Oda Y.
- Journal Title
  
  Cancer
  
  Volume: 未定 Issue: 6 Pages: 864-876
- DOI
  10.1002/cncr.28506
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24790352, KAKENHI-PROJECT-25293088, KAKENHI-PROJECT-25293325, KAKENHI-PROJECT-25893168, KAKENHI-PROJECT-26460435
[Journal Article] Activation of the Akt/mammalian target of rapamycin pathway in myxofibrosarcomas2014
- Author(s)
  Takahashi Y, Kohashi K, Yamada Y, Endo M, Setsu N, Ishii T, Yamamoto H, Iwamoto Y, Oda Y
- Journal Title
  
  Hum Pathol
  
  Volume: 45(5) Issue: 5 Pages: 984-993
- DOI
  10.1016/j.humpath.2013.12.012
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293088, KAKENHI-PROJECT-25293325, KAKENHI-PROJECT-25893168, KAKENHI-PROJECT-26460435, KAKENHI-PROJECT-26713046
[Journal Article] Phosphorylation of signal transducer and activator of transcription 3 in soft tissue leiomyosarcoma is associated with a better prognosis.2013
- Author(s)
  Setsu N
- Journal Title
  
  International Journal of Cancer
  
  Volume: 132 Issue: 1 Pages: 109-115
- DOI
  10.1002/ijc.27655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390107, KAKENHI-PROJECT-25293325
[Journal Article] Naturally occurring PD-1+ memory phenotype CD8 T cells belong to nonconventional CD8 T cells and are cyclophosphamide-sensitive regulatory T cells.2013
- Author(s)
  Sakuraba K
- Journal Title
  
  Journal of immunology
  
  Volume: 190 Issue: 4 Pages: 1560-1566
- DOI
  10.4049/jimmunol.1202464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790468, KAKENHI-PROJECT-25293325
[Journal Article] Y-box binding protein-1 regulates cell proliferation and is associated with clinical outcomes of osteosarcoma.2013
- Author(s)
  Fujiwara-Okada Y, Matsumoto Y, Fukushi J, Setsu N, Matsuura S, Kamura S, Fujiwara T, Iida K, Hatano M, Nabeshima A, Yamada H, Ono M, Oda Y, Iwamoto Y.
- Journal Title
  
  Br J Cancer
  
  Volume: 108 Issue: 4 Pages: 836-847
- DOI
  10.1038/bjc.2012.579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592192, KAKENHI-PROJECT-25293325
[Journal Article] Prognostic impact of the activation status of the Akt/mTOR pathway in synovial sarcoma.2013
- Author(s)
  Setsu N, Kohashi K, Fushimi F, Endo M, Yamamoto H, Takahashi Y, Yamada Y, Ishii T, Yokoyama K, Iwamoto Y, Oda Y.
- Journal Title
  
  Cancer
  
  Volume: 119 Issue: 19 Pages: 3504-3513
- DOI
  10.1002/cncr.28255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790352, KAKENHI-PROJECT-25293088, KAKENHI-PROJECT-25293325, KAKENHI-PROJECT-25893168
[Journal Article] Hematoma of the ligamentum flavum in the thoracic spine: report of two cases and possible role of the transforming growth factor beta-vascular endothelial growth factor signaling axis in its pathogenesis2013
- Author(s)
  Matsumoto Y, Fujiwara T, Imamura R, Okada Y, Harimaya K, Doi T, Kawaguchi K, Okada S, Yamada Y, Oda Y, Iwamoto Y
- Journal Title
  
  J Orthop Sci
  
  Volume: 18 Issue: 2 Pages: 347-54
- DOI
  10.1007/s00776-011-0150-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390292, KAKENHI-PUBLICLY-23123516, KAKENHI-PROJECT-23650327, KAKENHI-PROJECT-25293325
[Journal Article] Glypican 3 expression in tumors with loss of SMARCB1/INI1 protein expression.2013
- Author(s)
  Kohashi K
- Journal Title
  
  Human Pathology
  
  Volume: 44 Issue: 4 Pages: 526-533
- DOI
  10.1016/j.humpath.2012.06.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390107, KAKENHI-PROJECT-22591980, KAKENHI-PROJECT-23256006, KAKENHI-PROJECT-23592631, KAKENHI-PROJECT-24790352, KAKENHI-PROJECT-25253095, KAKENHI-PROJECT-25293325, KAKENHI-PROJECT-25670744
[Journal Article] Ly6C+ Ly6G- Myeloid-derived suppressor cells play a critical role in the resolution of acute inflammation and the subsequent tissue repair process after spinal cord injury.2013
- Author(s)
  Saiwai H, Kumamaru H, Ohkawa Y, Kubota K, Kobayakawa K, Yamada H, Yokomizo T, Iwamoto Y, Okada S.
- Journal Title
  
  J Neurochem.
  
  Volume: 125 Issue: 1 Pages: 74-88
- DOI
  10.1111/jnc.12135
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116002, KAKENHI-PROJECT-22390292, KAKENHI-PROJECT-23310134, KAKENHI-PROJECT-23650327, KAKENHI-PROJECT-23651195, KAKENHI-PUBLICLY-25110725, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-25293325, KAKENHI-PROJECT-25713053, KAKENHI-PUBLICLY-23114718, KAKENHI-PUBLICLY-23123516
[Journal Article] nnate memory phenotype CD4+ T cells play a role in early protection against infection with Listeria monocytogenes in a CDsoLdependent manner2011
- Author(s)
  Umeda K., Sun X. Guo Y., Yamada H., Shibata K. and Yoshikai Y
- Journal Title
  
  Micrbiol. Immunol
  
  Volume: 55 Pages: 645-56
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Notch-Hesl pathway is required for thedevelopment of ILliproducing y8 T cells2011
- Author(s)
  Shibata K., Yamada H., Sate T., Dejima S., Nakamura M., , Ikawa T., Hara H., Yamasaki S., Kageyama R., Iwakura Y., Kawamoto H., Ton H. and Yoshikai Y.
- Journal Title
  
  Blood
  
  Volume: 118 Pages: 586-93
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] CD30 ligand is a target for a novel biological therapy against allergic rhinitis2011
- Author(s)
  Fuchiwaki T., Sun X., Yamada H., Shibata K Muta H., Podack E. R. Kawauchi H and Yoshikai Y
- Journal Title
  
  Eur. J. Immunol
  
  Volume: 41 Pages: 2947-54
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Preferential Accumulation of Activated Th1 Cells Not Only in Rheumatoid Arthritis But Also in Osteoarthritis Joints.2011
- Author(s)
  Yamada H, Nakashima Y, Okazaki K,Mawatari T, Fukushi JI, Oyamada A, Fujimura K, Iwamoto Y, Yoshikai Y.
- Journal Title
  
  J Rheumatol.[Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] IL-li production by 78 T cells is important for the antitumor effect of Mycobacterium bovis bacillus CalmetteGuerin treatment against bladder cancer2011
- Author(s)
  Takeuchi A., Dejima T., Yamada H., Shibata K., Nakamura R., Eta M., Nakatani T., Naito S., and Yoshikai Y
- Journal Title
  
  Eur. J. Immunol
  
  Volume: 41 Pages: 246-51
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] A protective role of naturally occurring ILliAproducing 76 T cells in the lung at the early stage of systemic candidiasis in mice2011
- Author(s)
  Dejima T., Shibata K., Yamada H., Hara H., Iwakura Y., Naito S. and Yoshikai Y.
- Journal Title
  
  Infect. Immun
  
  Volume: 79 Pages: 4503-10
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Preferential accumulation of activated Thl cells in the joints of rheumatoid arthritis and osteoarthritis2011
- Author(s)
  Yamada H., Nakashima Y., Okazaki K., Mawatari T., Fukushi J, Oyamada A., Fujimura K, Iwamoto Y., and Yoshikai Y.
- Journal Title
  
  J. Rheumatol
  
  Volume: 38 Pages: 1569-75
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] IL-17 production by γδ T cells is important for the antitumor effect of Mycobacterium bovis bacillus Calmette-Guerin treatment against bladder cancer.2011
- Author(s)
  Takeuchi A, Dejima T, Yamada H, Shibata K, Nakamura R, Eto M, Nakatani T, Naito S, Yoshikai Y.
- Journal Title
  
  Eur J Immunol. 41(1)
  
  Pages: 246-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Interleukin-15 is critical in the pathogenesis of influenza A virus-induced acute lung injury.2010
- Author(s)
  Nakamura R, Maeda N, Shibata K, Yamada H, Kase T, Yoshikai Y.
- Journal Title
  
  J Virol. 84(11)
  
  Pages: 5574-5582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Antibody-mediated T-cell reduction or increased levels of chimerism overcome resistance to cyclophosphamide-induced tolerance in NKT-deficient mice.2010
- Author(s)
  Onzuka T, Tomita Y, Okano S, Shimizu I, Yamada H, Yoshikai Y, Tominaga R.
- Journal Title
  
  Scand J Immunol.
  
  Volume: 72 Pages: 106-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] CD30 Ligand Is a Target for a Novel Biological Therapy against Colitis Associated with Th17 Responses2010
- Author(s)
  Sun X, Yamada H, Shibata K, Muta H, Tani K, Podack ER, Iwakura Y, Yoshikai Y.
- Journal Title
  
  J Immunol.
  
  Volume: 185 Pages: 7671-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] CD30 ligand/CD30 plays a critical role in Th17 differentiation in mice.2010
- Author(s)
  Sun X, Yamada H, Shibata K, Muta H, Tani K, Podack ER, Yoshikai Y.
- Journal Title
  
  J Immunol
  
  Volume: 185 Pages: 2222-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] A critical role of CDso ligand in THli differentiation2010
- Author(s)
  Sun X. Yamada H., Shibata K., Muta H., Tani K., Podack E. R. Iwakura Y., and Yoshikai Y
- Journal Title
  
  J. Immunol
  
  Volume: 185 Pages: 2222-30
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Interleukin-ls is critical in the pathogenesis of influenza A virusinduced acute lung injury2010
- Author(s)
  Nakamura R., Maeda N., Shibata K. Yamada H., Kase T. and Yoshikai Y.
- Journal Title
  
  J. viral
  
  Volume: 84 Pages: 5574-82
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Current perspectives on the role of IL-17 in autoimmune disease2010
- Author(s)
  Yamada H
- Journal Title
  
  J Inflam Res.
  
  Volume: 3 Pages: 33-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Selective control of type I IFN induction by the Rae activator DOCK2 during TLRmediated plasmacytoid dendritic cell activation2010
- Author(s)
  otoh K., Tanaka Y., Nishikimi A., Nakamura R., Yamada H., Maeda N., Ishikawa T., Hoshino K., Uru no T., Cao Q, Higashi S., Kawaguchi Y, Enjoji M, Takayanagi, R., Kaisho T. Yoshikai, Y. and Fukui Y.
- Journal Title
  
  J. Exp. Med
  
  Volume: 207 Pages: 721-30
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] The LTB4-BLT1 Axis Mediates Neutrophil Infiltration and Secondary Injury in Experimental Spinal Cord Injury.2010
- Author(s)
  Saiwai H, Ohkawa Y, Yamada H, Kumamaru H, Harada A, Okano H, Yokomizo T, Iwamoto Y, Okada S.
- Journal Title
  
  Am J Pathol.
  
  Volume: 176 Pages: 2352-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Dual specificity phosphatasel6 is a negative regulator of INK activity in T cells2010
- Author(s)
  Tang C., Yamada H., Shibata K., Yoshida S., Wajjwalku W., and Yoshikai Y.
- Journal Title
  
  Microbiol. Immunol
  
  Volume: 54 Pages: 105-11
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] CD30 Ligand Is a Target for a Novel Biological Therapy against Colitis Associated with Th17 Responses.2010
- Author(s)
  Sun X, Yamada H, Shibata K, Muta H, Tani K, Podack ER, Iwakura Y, Yoshikai Y.
- Journal Title
  
  J Immunol. 185(12)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation.2010
- Author(s)
  Gotoh K, Tanaka Y, Nishikimi A, Nakamura R, Yamada H, Maeda N, Ishikawa T, Hoshino K, Uruno T, Cao Q, Higashi S, Kawaguchi Y, Enjoji M, Takayanagi R, Kaisho T, Yoshikai Y, Fukui Y.
- Journal Title
  
  J Exp Med
  
  Volume: 207 Pages: 721-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] IL-17 production by γδ T cells is important for the antitumor effect of Mycobacterium bovis bacillus Calmette-Guerin treatment against bladder cancer.2010
- Author(s)
  Takeuchi A, Dejima T, Yamada H, Shibata K, Nakamura R, Eto M, Nakatani T, Naito S, Yoshikai Y.
- Journal Title
  
  Eur J Immunol.
  
  Volume: 41 Pages: 246-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Current perspectives on the role of IL-17 in autoimmune disease.2010
- Author(s)
  Yamada H.
- Journal Title
  
  J.Inflam Res. 3
  
  Pages: 33-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] The LTB4-BLT1 Axis Mediates Neutrophil Infiltration and Secondary Injury in Experimental Spinal Cord Injury.2010
- Author(s)
  Saiwai H, Ohkawa Y, Yamada H, Kumamaru H, Harada A, Okano H, Yokomizo T, Iwamoto Y, Okada S.
- Journal Title
  
  Am J Pathol. 176(5)
  
  Pages: 2352-2366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] CDso ligand is a target for a novel biological therapy against colitis associated with Th17 responses2010
- Author(s)
  Sun X. Yamada H., Shibata K., Muta H., Tani K., Podack E. R. Iwakura Y. and Yoshikai Y.
- Journal Title
  
  J. Immunol
  
  Volume: 185 Pages: 7671-80
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Interleukin-15 is critical in the pathogenesis of influenza A virus-induced acute lung injury.2010
- Author(s)
  Nakamura R, Maeda N, Shibata K, Yamada H, Kase T, Yoshikai Y.
- Journal Title
  
  J Virol.
  
  Volume: 84 Pages: 5574-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Antibody-Mediated T-cell reduction or increased levels of chimerism overcome resistance to cyclophosph amide-induced tolerance in NKT-deficient mice2010
- Author(s)
  T.Onzuka, Y.Tomita, S.Okano, I.Shimizu, H.Yamada, Y.Yoshikal, R.Tominaga
- Journal Title
  
  Scand J Immunol 72
  
  Pages: 106-117
- Data Source
  KAKENHI-PROJECT-20390371
[Journal Article] Th17 cells and human arthritic diseases.2010
- Author(s)
  Yamada H.
- Journal Title
  
  Nihon Rinsho Meneki Gakkai Kaishi. 33(4)
  
  Pages: 214-221
- NAID
  10027753748
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] CD30 ligand/CD30 plays a critical role in Th17 differentiation in mice.2010
- Author(s)
  Sun X, Yamada H, Shibata K, Muta H, Tani K, Podack ER, Yoshikai Y.
- Journal Title
  
  J Immunol. 185(4)
  
  Pages: 2222-2230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Mechanism of Synergistic Antitumor Effect of Sorafenib and Interferon-α on Treatment of Renal Cell Carcinoma2010
- Author(s)
  Takeuchi A, Eto M, Tatsugami K, Yamada H, Oki T, Kiyoshima K, Yoshikai Y, Naito S.
- Journal Title
  
  J Urol.
  
  Volume: 184 Pages: 2549-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] IL-15 protects antigen-specific CD8+ T cell contraction after Mycobacterium bovis bacillus Calmette-Guerin infection.2009
- Author(s)
  Tang C, Yamada H, Shibata K, Yoshida SI, Wajjwalku W, Yoshikai Y.
- Journal Title
  
  J Leukoc Biol. 86(1)
  
  Pages: 187-194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Protective role of Fas-FasL signaling in lethal infection with herpes simplex virus type 2 in mice.2009
- Author(s)
  Ishikawa T, Yamada H, Oyamada A, Goshima F, Nishiyama Y, Yoshikai Y.
- Journal Title
  
  J Virol. 83(22)
  
  Pages: 11777-11783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Effects of Toll-like receptor agonist on the induction of mixed chimerism in cyclophosphamide-induced tolerance2009
- Author(s)
  T.Onzuka, Y.Tomita, S.Okano, I.Shimizu, H.Yamada, Y.Yoshikai, R.Tominaga
- Journal Title
  
  Scand J Immunol 70
  
  Pages: 423-430
- Data Source
  KAKENHI-PROJECT-20390371
[Journal Article] Donor CD4 T Cells Are Critical in Allogeneic Stem Cell Transplantation against Murine Solid Tumor.2009
- Author(s)
  Kamiryo Y, Eto M, Yamada H, Yajima T, Harano M, Takeuchi A, Tatsugami K, Hamaguchi M, Naito S, Yoshikai Y.
- Journal Title
  
  Cancer Res. 69(12)
  
  Pages: 5151-5158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Tyrosine kinase 2 plays critical roles in the pathogenic CD4 T cell responses for the development of experimental autoimmune encephalomyelitis2009
- Author(s)
  Oyamada A, Ikebe H, Itsumi M, Saiwai H, Okada S, Shimoda K, Iwakura Y, Nakayama K, Iwamoto Y, Yoshikai Y, Yamada H
- Journal Title
  
  J Immunol. 183
  
  Pages: 7539-7546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Direct recognition of mycobacterial cord factor, trehalose dimycolate, by C-type lectin Mincle2009
- Author(s)
  Ishikawa E, Ishikawa T, Morita Y, Toyonaga K, Yamada H, Takeuchi O, Akira S, Kinoshita T, Yoshikai Y, Yamasaki S
- Journal Title
  
  J Exp Med. 206
  
  Pages: 2879-2888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Tyrosine kinase 2 plays critical roles in the pathogenic CD4 T cell responses for the development of experimental autoimmune encephalomyelitis.2009
- Author(s)
  Oyamada A, Ikebe H, Itsumi M, Saiwai H, Okada S, Shimoda K, Iwakura Y, Nakayama K, Iwamoto Y, Yoshikai Y, Yamada H.
- Journal Title
  
  J Immunol. 183(11)
  
  Pages: 7539-7546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Donor CD4 T Cells Are Critical in Allogeneic Stem Cell Transplantation against Murine Solid Tumor2009
- Author(s)
  Kamiryo Y, Eto M, Yamada H, Yajima T, Harano M, Takeuchi A, Tatsugami K, Hamaguchi M, Naito S, Yoshikai Y.
- Journal Title
  
  Cancer Res.
  
  Pages: 5151-5158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Oral administration of xanthan gum enhances antitumor activity through Toll-like receptor 4.2009
- Author(s)
  Takeuchi A, Kamiryou Y, Yamada H, Eto M, Shibata K, Haruna K, Naito S, Yoshikai Y.
- Journal Title
  
  Int Immunopharmacol. 9(13-14)
  
  Pages: 1562-1567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] IL-15 protects antigen-specific CD8+ T cell contraction after Mycobacterium bovis bacillus Calmette-Guerin infection2009
- Author(s)
  Tang C, Yamada H, Shibata K, Yoshida SI, Wajjwalku W, Yoshikai Y.
- Journal Title
  
  J Leukoc Biol. 86
  
  Pages: 187-194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Tyrosine kinase 2 plays critical roles in the pathogenic CD4T cell responses for the development of experimental autoimmune encephalomyelitis2009
- Author(s)
  Oyamada A., et al.
- Journal Title
  
  J. Immunol. 183
  
  Pages: 7539-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Direct recognition of mycobacterial cord factor, trehalose dimycolate, by C-type lectin Mincle.2009
- Author(s)
  Ishikawa E, Ishikawa T, Morita Y, Toyonaga K, Yamada H, Takeuchi O, Akira S, Kinoshita T, Yoshikai Y. Yamasaki S.
- Journal Title
  
  J Exp Med. 206(13)
  
  Pages: 2879-2888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] IL-15 is critical for the maintenance and innate functions of self-specific CD8(+) T cells.2009
- Author(s)
  Itsumi M, Yoshikai Y, Yamada H.
- Journal Title
  
  Eur J Immunol. 39(7)
  
  Pages: 1784-1793
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Oral administration of xanthan gum enhances antitumor activity through Toll-like receptor 42009
- Author(s)
  Takeuchi A., Kamiryou Y., Yamada H., Eta M., Shibata K., Haruna K., Naito S., and Yoshikai Y.
- Journal Title
  
  Int. Immunopharma.
  
  Volume: 9 Pages: 1562-7
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] 炎症と免疫2009
- Author(s)
  柴田健輔., 山田久方, 吉開泰信.
- Journal Title
  
  IL-17とγδ型Tリンパ球
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] IL-15 is critical for the maintenance and innate functions of self-specific CD8(+)T cells2009
- Author(s)
  Itsumi M, Yoshikai Y, Yamada H.
- Journal Title
  
  Eur J Immunol. 39
  
  Pages: 1784-1793
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Effects of lipopolysaccharide on the induction of mixed chimerism in cyclophosphamide-induced tolerance2009
- Author(s)
  Onzuka T, Tomita Y, Shimizu I, Okano S, Yamada H, Yoshikai Y, Tominaga R.
- Journal Title
  
  Scand J Immunol. 70
  
  Pages: 423-430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Tyrosine kinase 2 plays critical roles in the pathogenic CD4 T cell responses for the development of experimental autoimmune encephalomyelitis2009
- Author(s)
  Oyamada A., Ikebe H., Itsumi M., Saiwai H., Okada, S., Shimoda, K., Iwakura, Y., Nakayama, K., Iwamoto, Y., Yoshikai, Y. and Yamada H.
- Journal Title
  
  J. Immuol
  
  Volume: 183 Pages: 7539-46
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Th17 cells in human rheumatoid arthritis.2009
- Author(s)
  Yamada H.
- Journal Title
  
  Nihon Rinsho Meneki Gakkai Kaishi. 32(4)
  
  Pages: 249-255
- NAID
  10026352183
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Direct recognition of mycobacterial cord factor, trehalose dimycolate, by C-type lect in Mincle2009
- Author(s)
  Ishikawa E., Ishikawa T., Marita Y., Toyonaga K., Yamada H., Takeuchi 0., Akira S., Kinoshita T., Yoshikai Y. and Yamasaki S.
- Journal Title
  
  J. Exp. Med
  
  Volume: 206 Pages: 2879-88
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Protective role of Fas-FasL signaling in lethal infection with herpes simplex virus type 2 in mice2009
- Author(s)
  Ishikawa T, Yamada H, Oyamada A, Goshima F, Nishiyama Y, Yoshikai Y.
- Journal Title
  
  J Virol. 83
  
  Pages: 11777-11783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Exogenous IL-15 protects CD8+ T Cell Contraction after BCG vaccination but fails to provide protection against subsequent infection with Mycobacterium tuberculosis2009
- Author(s)
  Tang C., Yamada H., Shibata K., Yoshida S., Wajjwalku W., and Yoshikai Y.
- Journal Title
  
  J. Leuko Biol
  
  Volume: 86 Pages: 187-94
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Donor CD4 T cells are critical in allogeneic stem cell transplantation against murine solid tumor2009
- Author(s)
  Kamiryo Y., , Eta M., Yamada H., Harano M., Yajima T., Harano M., Tatsugami K., Hamaguchi M., Takeuchi A., Naito S., and Yoshikai Y.
- Journal Title
  
  Cancer Research
  
  Volume: 69 Pages: 5151-8
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Protective role of Fas-FasL signaling in lethal infection with herpes simplex virus type 2 in mice2009
- Author(s)
  Ishikawa T., Yamada H., Maeda Y., Goshima F., Nishiyama, Y. and Yoshikai Y.
- Journal Title
  
  J. viral
  
  Volume: 83 Pages: 11777-83
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] L-Is is critical to the maintenance and functions of selfspecific memoryphenotype CD8 T cells2009
- Author(s)
  Itsumi M., Yoshikai Y. and Yamada H
- Journal Title
  
  Eur J. Immunol
  
  Volume: 39 Pages: 1784-93
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Oral administration of xanthan gum enhances antitumor activity through Toll-like receptor 42009
- Author(s)
  Takeuchi A, Kamiryou Y, Yamada H, Eto M, Shibata K, Haruna K, Naito S, Yoshikai Y.
- Journal Title
  
  Int Immunopharmacol 9
  
  Pages: 1562-1567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] A novel role of CD30L/CD30 signaling by T-T cell interaction in Th1 response against mycobacterial infection.2008
- Author(s)
  Tang C, Yamada H, Shibata K, Muta H, Wajjwalku W, Podack ER, Yoshikai Y.
- Journal Title
  
  J Immunol. 181(9)
  
  Pages: 6316-6327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Tyk2-signaling plays an important role in host defense against Escherichia coli through IL-23-induced IL-17 production by gammadelta T cells.2008
- Author(s)
  Nakamura R, Shibata K, Yamada H, Shimoda K, Nakayama K, Yoshikai Y.
- Journal Title
  
  J Immunol. 181(3)
  
  Pages: 2071-2075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.2008
- Author(s)
  Hikosaka Y, Nitta T, Ohigashi I, Yano K, Ishimaru N, Hayashi Y, Matsumoto M, Matsuo K, Penninger JM, Takayanagi H, Yokota Y, Yamada H, Yoshikai Y, Inoue J, Akiyama T, Takahama Y.
- Journal Title
  
  Immunity. 29(3)
  
  Pages: 438-450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Role of the cytokine profiles produced by iNKT cells in the initial phase of cyclophosphamide-induced tolerance2008
- Author(s)
  Onzuka T, Tomita Y, Shimizu I, Okano S, Yamada H, Yoshikai Y, Tominaga R
- Journal Title
  
  Transplantatian 86(9)
  
  Pages: 1301-1310
- Data Source
  KAKENHI-PROJECT-20390371
[Journal Article] Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis.2008
- Author(s)
  Yamada H, Nakashima Y, Okazaki K, Mawatari T, Fukushi JI, Kaibara N, Hori A, Iwamoto Y, Yoshikai Y.
- Journal Title
  
  Ann Rheum Dis. 67(9)
  
  Pages: 1299-1304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Identification of CD25+ gammadelta T cells as fetal thymus-derived naturally occurring IL-17 producers.2008
- Author(s)
  Shibata K, Yamada H, Nakamura R, Sun X, Itsumi M, Yoshikai Y.
- Journal Title
  
  J Immunol. 181(9)
  
  Pages: 5940-5947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Comparative histopathological analysis between tenosynovitis and joint synovitis in rheumatoid arthritis.2008
- Author(s)
  Kaibara N, Yamada H, Shuto T, Nakashima Y, Okazaki K, Miyahara H, Esaki Y, Hirata G, Iwamoto Y
- Journal Title
  
  Histopathology 52
  
  Pages: 856-864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Comparative histopathological analysis between tenosynovitis and joint synovitis in rheumatoid arthritis.2008
- Author(s)
  Kaibara N, Yamada H, Shuto T, Nakashima Y, Okazaki K, Miyahara H, Esaki Y, Hirata G, Iwamoto Y.
- Journal Title
  
  Histopathology. 52(7)
  
  Pages: 856-864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Identification of CD25+ gammadelta T cells as fetal thymus-derived naturally occurring IL-17 producers.2008
- Author(s)
  Shibata K, Yamada H, Nakamura R, Sun X, Itsumi M, Yoshikai Y.
- Journal Title
  
  Journal of Immunology 181
  
  Pages: 5940-5947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Comparative histopathological analysis between tenosynovitis and joint synovitis in rheumatoid arthritis2008
- Author(s)
  Kaibara N, Yamada H, Shuto T, Nakashima Y, Okazaki K, Miyahara H, Esaki Y, Hirata G, Iwamoto Y
- Journal Title
  
  Histopathology 52(7)
  
  Pages: 856-864
- Data Source
  KAKENHI-PROJECT-17591581
[Journal Article] Thl but not Th17 cells predominate in the joints of patients with rheumatoid arthritis2008
- Author(s)
  Yamada H, Nakashima Y, Okazaki K, Mawatari T, Fukushi JI, Kaibara N, Hori A, Iwamoto Y, Yoshikai Y.
- Journal Title
  
  Annals of Rheumatic Disease. 67
  
  Pages: 1299-1304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591783
[Journal Article] Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis2008
- Author(s)
  Yamada H, Nakashima Y, Okazaki K, Mawatari T, Fukushi JI, Kaibara N, Hori A, Iwamoto Y, Yoshikai Y
- Journal Title
  
  Ann Rheum Dis 67(9)
  
  Pages: 1299-1304
- Data Source
  KAKENHI-PROJECT-17591581
[Journal Article] RAにおける手指・足趾関節破壊と生物学的製剤による抑制効果2008
- Author(s)
  中島康晴, 岡崎賢, 馬渡太郎, 福士純一, 山田久方, 小山田亜希子, 岩本幸英, 都留智己
- Journal Title
  
  九州リウマチ 28(2)
  
  Pages: 70-74
- Data Source
  KAKENHI-PROJECT-17591581
[Journal Article] 抗TNF療法の荷重関節に対する効果2007
- Author(s)
  中島康晴, 岡崎賢, 馬渡太郎, 福士純一, 貝原信孝、山田久方, 堀亜希子, 前田健、吉澤誠司,首藤敏秀, 岩本幸英
- Journal Title
  
  リウマチ科 38(5)
  
  Pages: 458-463
- Data Source
  KAKENHI-PROJECT-17591581
[Journal Article] RAにおける関節予後の検討-インフリキシマブとMTX 使用例の比較-
- Author(s)
  中島康晴, 岡崎賢, 馬渡太郎, 福士純一, 山田久方, 堀亜希子, 吉澤誠司, 都留智巳, 首藤敏秀, 岩本幸英
- Journal Title
  
  第52回日本リウマチ学会総会・学術集会, 第17回国際リウマチシンポジウム
- Data Source
  KAKENHI-PROJECT-17591581
[Presentation] ヒト滑膜組織常在性マクロファージは炎症刺激に対して低反応である2022
- Author(s)
  甲斐一広、山田久方、鶴居亮輔、櫻木高秀、櫻庭康司、赤崎幸穂、藤原稔史、津島秀俊、川原慎也、澤新一郎、中島康晴
- Organizer
  第50回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-22K09382
[Presentation] 関節リウマチにおけるGM-CSF産生CD４T細胞サブセットの同定2017
- Author(s)
  山田久方、原口明久、櫻庭康司、岡崎賢、福士純一、水内秀城、赤崎幸穂、江崎幸雄、嘉村聡志、藤村謙次郎、近藤正一、宮原寿明、中島康晴、吉開泰信
- Organizer
  第45回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-16K10907
[Presentation] SMARCB1/INI1蛋白欠失腫瘍群におけるERG, SALL4発現の診断的意義の検討2015
- Author(s)
  孝橋賢一, 山田裕一, 山元英崇, 石井武彰, 井浦国生, 前川　啓, 戸次大史, 大塚　洋, 岩本幸英, 小田義直
- Organizer
  第48回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  サンポートホール高松、かがわ国際会議場（香川）
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-25293325
[Presentation] 脱分化型脂肪肉腫におけるAkt/mTOR pathwayおよびMAPK pathwayの解析2015
- Author(s)
  石井武彰, 孝橋賢一, 井浦国生, 前川　啓, 戸次大史, 山田裕一, 山元英崇, 岩本幸英, 小田義直
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場（愛知）
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-25293325
[Presentation] 未分化多形性肉腫におけるHSP90の発現上昇およびHSP90阻害薬の抗腫瘍効果2015
- Author(s)
  戸次大史, 孝橋賢一, 前川　啓, 山田裕一, 山元英崇, 播广谷勝三, 井浦国生, 大塚　洋, 箱﨑道之, 鍋島和樹, 岩本幸英, 小田義直
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25293325
[Presentation] Successful in vitro culture of synovial explants from rheumatoid arthritis at the air-liquid interface.2014
- Author(s)
  Hisakata Yamada, Koji Sakuraba, Yasunobu Yoshikai
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  京都市
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-24591449
[Presentation] 骨格形成におけるTGF-βシグナルの果たす役割に関する研究2013
- Author(s)
  松延知哉、松本嘉寛、大石正信、岩本幸英、山田吉彦
- Organizer
  第20回BMP研究会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-25293325
[Presentation] 滑膜肉腫におけるAkt/mTOR経路の活性化と臨床病理学的背景の検討2013
- Author(s)
  薛宇孝、孝橋賢一、遠藤誠、山元英崇、髙橋祐介、山田裕一、石井武彰、横山庫一郎、横山良平、岩本幸英、小田義直
- Organizer
  第86回日本整形外科学会学術総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-25293325
[Presentation] 横紋筋肉腫におけるFOXM1発現の検討2013
- Author(s)
  久田正昭、孝橋賢一、中面哲也、三好きな、山田裕一、山元英崇、田口智章、岩本幸英、小田義直
- Organizer
  第46回日本整形外科骨･軟部腫瘍学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25293325
[Presentation] 類上皮肉腫におけるAkt/mTOR経路関連蛋白の発現検討2013
- Author(s)
  孝橋賢一、髙橋祐介、山田裕一、石井武彰、井浦国生、前川啓、山元英崇、岩本幸英、小田義直
- Organizer
  第46回日本整形外科骨･軟部腫瘍学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25293325
[Presentation] Il-21 plays critical roles in the production of pathogenic autoantibodies in a murine model of autoimmune arthritis2012
- Author(s)
  山田久方
- Organizer
  日本免疫学会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24591449
[Presentation] Notchr-Hes1経路は自然発生IL-17産生γδT細胞分化に必要である2011
- Author(s)
  柴田健輔、山田久方、吉開泰信
- Organizer
  第22回日本生体防御学会学術総会
- Place of Presentation
  那覇市
- Data Source
  KAKENHI-PROJECT-21390130
[Presentation] 自然発生IL 17産生γδT細胞活性化におけるCDBOLigandの役割2011
- Author(s)
  孫遜、郭穎、黄銀霞、柴田健輔、山田久方、吉開泰信
- Organizer
  第22回日本生体防御学会学術総会
- Place of Presentation
  那覇市
- Data Source
  KAKENHI-PROJECT-21390130
[Presentation] 自然発生IL 17産生γδT細胞機能制御機構の解析2011
- Author(s)
  中村真隆、柴田健輔、山田久方、吉開泰信
- Organizer
  第22回日本生体防御学会学術総会
- Place of Presentation
  那覇市
- Data Source
  KAKENHI-PROJECT-21390130
[Presentation] Candi da al bi cans感染防御におけるIL-17産生γδT細胞の役割2011
- Author(s)
  出嶋卓、柴田健輔、山田久方、吉開泰信
- Organizer
  第22回日本生体防御学会学術総会
- Place of Presentation
  那覇市
- Data Source
  KAKENHI-PROJECT-21390130
[Presentation] Tyk2 is indispensable for the development of experimental autoimmune disease2010
- Author(s)
  A.Oyamada, Y.Yoshikai, H.Yamada
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸市
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-20591783
[Presentation] Interleukin-15 is critical in the pathogenesis of influenza A virus-induced acute lung injury2010
- Author(s)
  R.Nakamura, N.Maeda, O.Noyori, K.Shibata, H.Yamada, Y.Yoshikai
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸市
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-20591783
[Presentation] マウスコラーゲン誘導性関節炎におけるTyk2の重要性2010
- Author(s)
  小山田亜希子、藤村謙次郎、岩本幸英、吉開泰信、山田久方
- Organizer
  第54回日本リウマチ学会総会・学術集会
- Place of Presentation
  神戸市
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-20591783
[Presentation] Interleukin-15 is critical in the pathogenesis of influenza A virus-induced acute lung injury.2010
- Author(s)
  R.Nakamura, N.Maeda, O.Noyori, K.Shibata, H.Yamada, Y.Yoshikai
- Organizer
  14th International Congress of Immunology.
- Place of Presentation
  神戸市
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-20591783
[Presentation] Preferential accumulation of Th1 cells in the joints of rheumatoid arthritis and osteoarthritis2010
- Author(s)
  H.Yamada, A.Oyamada, Y.Yoshikai
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸市
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-20591783
[Presentation] The basic helix-loop-helix protein HES1は自然発生IL-17産生γδT細胞分化に必要である2010
- Author(s)
  柴田健輔、山田久方、吉開泰信
- Organizer
  第21回日本生体防御学会学術総会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-20591783
[Presentation] Preferential accumulation of Th1 cells in the joints of rheumatoid arthritis and osteoarthritis.2010
- Author(s)
  H.Yamada, A.Oyamada, Y.Yoshikai
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸市
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-20591783
[Presentation] BCG膀胱内注入療法の抗腫瘍効果にはγδT細胞によるIL 17産生が重要である2009
- Author(s)
  武内在雄,山田久方,柴田健輔,吉開泰信
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-21390130
[Presentation] IL-15は自己抗原特異的CD8陽性T細胞の維持と自然免疫機能に重要である2009
- Author(s)
  山田久方、逸見百江、吉開泰信
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪市
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-20591783
[Presentation] 関節リウマチの関節内CD4T細胞サブセットの解析2009
- Author(s)
  山田久方、中島康晴、岡崎賢、馬渡太郎、福士純一、小山田亜希子、岩本幸英
- Organizer
  第53回日本リウマチ学会総会・学術集会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20591783
[Presentation] ヒト関節リウマチとTh17細胞2009
- Author(s)
  山田久方
- Organizer
  第37回日本臨床免疫学会総会
- Place of Presentation
  東京都
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-20591783
[Presentation] IL-15は自己抗原特異的CD8T細胞の維持や機能を制御する2009
- Author(s)
  逸見百江,吉開泰信,山田久方
- Organizer
  第20回日本生体防御学会学術総会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-21390130
[Presentation] IL-15は自己抗原特異的CD8T細胞の維持や機能を制御する2009
- Author(s)
  逸見百江、吉開泰信、山田久方
- Organizer
  第20回日本生体防御学会学術総会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20591783
[Presentation] 自己抗原特異的メモリー型T細胞の骨髄由来細胞による正の選択2008
- Author(s)
  山田久方、逸見百江、吉開泰信
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都市
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-20591783
[Presentation] インフリキシマブによる関節破壊抑制効果の検討2008
- Author(s)
  中島康晴, 岡崎賢, 馬渡太郎, 福士純一, 山田久方, 吉澤誠司, 首藤敏秀, 都留智巳, 岩本幸英
- Organizer
  第37回リウマチの外科研究会
- Year and Date
  2008-08-23
- Data Source
  KAKENHI-PROJECT-17591581
[Presentation] IL-15 is critical to the development and functions of self-specific memory phenotype CD8 T cells2008
- Author(s)
  Momoe Itsumi, Yasunobu Yoshikai, Hisakata Yamada
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都市
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-20591783
[Presentation] インフリキシマブによるRA の荷重関節破壊抑制効果の検討2008
- Author(s)
  中島康晴, 岡崎賢, 馬渡太郎, 福士純一, 山田久方, 堀亜希子, 吉澤誠司, 首藤敏秀, 前田健, 岩本幸英
- Organizer
  第81回日本整形外科学会学術総会
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-17591581
[Presentation] RAにおける関節予後の検討-インフリキシマブとMTX 使用例の比較-2008
- Author(s)
  中島康晴, 岡崎賢, 馬渡太郎, 福士純一, 山田久方, 堀亜希子, 吉澤誠司, 都留智巳, 首藤敏秀, 岩本幸英
- Organizer
  第52回日本リウマチ学会総会・学術集会, 第17回国際リウマチシンポジウム
- Year and Date
  2008-04-23
- Data Source
  KAKENHI-PROJECT-17591581
[Presentation] 生物学的製剤によるRA の関節破壊抑制効果の検討2008
- Author(s)
  中島康晴, 岡崎賢, 馬渡太郎, 福士純一, 山田久方, 堀亜希子, 首藤敏秀, 岩本幸英
- Organizer
  第35 回九州リウマチ学会
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-17591581
[Presentation] 滑膜肉腫臨床検体におけるmelanoma inhibitory activity proteinの発現の検討
- Author(s)
  前川啓, 孝橋賢一, 井浦国生, 石井武彰, 高橋祐介, 山田裕一, 岩本幸英, 小田義直
- Organizer
  第47回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-07-17 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-25293325
[Presentation] IL-21シグナルはコラーゲン誘導関節炎の発症に重要な役割を果たす
- Author(s)
  櫻庭康司、小山田亜希子、藤村謙次郎、橋口智光、岩本幸英、吉開泰信、山田久方
- Organizer
  第57回日本リウマチ学会総会・学術集会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-24591449
[Presentation] 悪性末梢神経鞘腫瘍におけるPTENの発現解析と予後的意義の検討
- Author(s)
  遠藤誠, 薛宇孝, 箱﨑道之, 戸次大史, 井浦国生, 前川啓, 石井武彰, 高橋祐介, 山田裕一, 孝橋賢一, 山元英崇, 松延知哉, 松本嘉寛, 播广谷勝三, 岩本幸英, 小田義直
- Organizer
  第47回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-07-17 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-25293325
[Presentation] 癌精巣抗原 PRAME と NY - ESO - 1 の脂肪肉腫での発現と粘液/円形細胞型脂肪肉腫における臨床病理学的因子との関連
- Author(s)
  井浦国生, 孝橋賢一 , 石井武彰, 前川啓, 山田裕一, 戸次大史, 山元英崇, 遠藤誠, 岩本幸英, 小田義直
- Organizer
  第 73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25293325

1. KATAYAMA Yoshiki (70284528)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. YOSHIKAI Yasunobu (90158402)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NAKASHIMA Yasuharu (10304784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. TOMITA Yukihiro (90180174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. SHBATA Kensuke (50529972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
6. 中島淳博 (10260704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 清水一郎 (70444841)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 岩本幸英 (00213322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
9. 松本嘉寛 (10346794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. 松延知哉 (20543416)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 岡田誠司 (30448435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 福士純一 (40444806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 小田義直 (70291515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
14. KOHASHI Kenichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
15. 吉開康信

# of Collaborated Projects: 0 results

# of Collaborated Products: 27 results
16. 松本和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 山元英崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
18. 櫻庭康司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 横溝岳彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamada Hisakata 山田 久方

山田 久方 ヤマダ ヒサカタ

YAMADA Hisakata 山田 久方

Research Projects

Research Products

Co-Researchers

滑膜常在マクロファージを中心とした関節炎症病態の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating the pathogenic roles of CD4T cells in rheumatoid arthritisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

悪性骨軟部腫瘍における薬剤耐性獲得機構の解明

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigating T cells helping autoantibody production in rheumatoid arthritisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The roles of innate T cells in bacterial infection

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental organ transplantation: Application of the drug-induced immune tolerance-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of immune responses by IL-15Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Nano-treatment for musculoskeletal chronic inflammation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

関節炎症性疾患における新規サイトカインレセプターWSX-1の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Synovial-tissue resident macrophages play proinflammatory functions in the pathogenesis of RA while maintaining the phenotypes in the steady state2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] T cells specific for post-translational modifications escape intrathymic tolerance induction2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Th1 is the predominant helper T cell subset that produces GM-CSF in the joint of rheumatoid arthritis.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of the Akt-mTOR and MAPK pathways in dedifferentiated liposarcomas2016

Author(s)

Journal Title

DOI

Data Source

Yamada Hisakata 山田久方

山田久方ヤマダヒサカタ

YAMADA Hisakata 山田久方